[ { "uniprot_canonical_ac": "Q03043-1", "uniprot_id": "KGP24_DROME", "mass": 121341.0, "length": 1088, "protein_name": "cGMP-dependent protein kinase, isozyme 2 forms cD4/T1/T3A/T3B", "gene_name": "for", "organism": "Fruit fly", "refseq_name": "foraging, isoform A", "refseq_ac": "NP_477487", "gene_names_uniprotkb": "for; 142251_at; BcDNA:GM08338; CG10033; DG2; Dg2; Dmel\\CG10033; Dmel_CG10033; For; PGK2; PKG2; PKG; Pkg24A; Pkg2; anon-WO0140519.260; anon-WO02059370.47; dg2; l(2)06860", "gene_names_refseq": "142251_at; BcDNA:GM08338; CG10033; DG2; Dg2; Dmel\\CG10033; FOR/PKG; For; PKG2; PKG; Pkg24A; Pkg2; anon-WO0140519.260; anon-WO02059370.47; dg2; for; l(2)06860", "protein_names_uniprotkb": "cGMP-dependent protein kinase, isozyme 2 forms cD4/T1/T3A/T3B; 2.7.11.12; Foraging protein; cGK", "protein_names_refseq": "CG10033-PA; for-PA; foraging, isoform A", "tax_id": 7227, "disease": "hypertension (Disease Ontology:DOID:10763); thoracic aortic aneurysm (Disease Ontology:DOID:14004); epilepsy (Disease Ontology:DOID:1826); impotence (Disease Ontology:DOID:1875); hypogonadism (Disease Ontology:DOID:1924); allergic rhinitis (Disease Ontology:DOID:4481); obesity (Disease Ontology:DOID:9970)", "pathway": " (dme:Dmel_CG10033); (R-DME-1474151); (R-DME-392517); (R-DME-9648002)", "pathway_count": 4, "publication_count": 14, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;18327897;25589440;26109356;26109357;2732245", "class_list": "", "function": "", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 7, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "A4V042;Q24304;Q9I7Q1;Q9VQT2", "ec_number_list": "2.7.11.17;2.7.11.1;2.7.11.13;2.7.11.24;2.7.11.22;1.1.1.153;2.7.11.21;3.6.5.2;5.6.1.8;2.7.11.11;2.7.11.23;4.2.3.12;2.7.12.1;2.7.11.25;2.7.11.12;2.7.12.2;2.7.10.2;2.7.11.39", "go_molecular_function": "GO:0004692 cGMP-dependent protein kinase activity;GO:0005524 ATP binding;GO:0030553 cGMP binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005886 plasma membrane", "go_biological_process": "GO:0046959 habituation;GO:0032095 regulation of response to food;GO:0007614 short-term memory;GO:0008016 regulation of heart contraction;GO:0007631 feeding behavior", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "Q03043-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P22810-1", "uniprot_id": "HMOC_DROME", "mass": 55187.0, "length": 542, "protein_name": "Homeotic protein ocelliless", "gene_name": "oc", "organism": "Fruit fly", "refseq_name": "ocelliless, isoform C", "refseq_ac": "NP_001014727", "gene_names_uniprotkb": "oc; CG12154; Dmel\\CG12154; Dmel_CG12154; OC; Oc; Otd; Otx; l(1)7Ff; l(1)8Ac; oc2; orthodenticle; ort; otd; uvi", "gene_names_refseq": "CG12154; Dmel\\CG12154; OC; Oc; Otd; Otx; l(1)7Ff; l(1)8Ac; oc2; oc; orthodenticle; ort; otd; uvi", "protein_names_uniprotkb": "Homeotic protein ocelliless; Protein orthodenticle", "protein_names_refseq": "CG12154-PC; oc-PC; ocelliless, isoform C; ocelliless; orthodentical; orthodenticle; uvi-insensitive", "tax_id": 7227, "disease": "combined pituitary hormone deficiency 6 (Disease Ontology:DOID:0061022); Leber congenital amaurosis 7 (Disease Ontology:DOID:0110333); cone-rod dystrophy 2 (Disease Ontology:DOID:0111005); syndromic microphthalmia 5 (Disease Ontology:DOID:0111806); retinal degeneration (Disease Ontology:DOID:8466)", "pathway": " (dme:Dmel_CG12154)", "pathway_count": 1, "publication_count": 14, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;12967559;16110336;17569856;17569867;1979296;25589440;26109356;26109357;8575625", "class_list": "", "function": "Transcriptional regulator involved in pattern formation and cell determination in the embryonic CNS and larval imaginal disks. Also later in development to coordinate the expression of regulatory and structural genes required for photoreceptor cell fate in the ocelli. Has a dual role in the terminal differentiation of subtypes of photoreceptors by regulating rhodopsin (rh) expression: essential for establishing the expression of rh genes in the pale subset of ommatidia as well as repressing Rh6 in outer photoreceptors., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q59E69;Q6NNU8;Q9W3D0", "ec_number_list": "", "go_molecular_function": "GO:0042803 protein homodimerization activity;GO:0046982 protein heterodimerization activity;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0007399 nervous system development;GO:0010628 positive regulation of gene expression", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "P22810-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q4V622-1", "uniprot_id": "CCH2R_DROME", "mass": 53531.0, "length": 489, "protein_name": "Neuropeptide CCHamide-2 receptor", "gene_name": "CCHa2-R", "organism": "Fruit fly", "refseq_name": "CCHamide-2 receptor, isoform B", "refseq_ac": "NP_001163060", "gene_names_uniprotkb": "CCHa2-R; CCH2aR; CCHa2R; CCHa2r; CCHamide-2 R; CG14593; CG14594; Dmel\\CG14593; Dmel_CG14593; anon-WO0131005.23", "gene_names_refseq": "CCH2aR; CCHa2-R; CCHa2R; CCHa2r; CCHamide-2 R; CG14593; CG14594; Dmel\\CG14593; anon-WO0131005.23", "protein_names_uniprotkb": "Neuropeptide CCHamide-2 receptor", "protein_names_refseq": "CCHa2-R-PB; CCHamide-2 receptor, isoform B; CCHamide-2 receptor; CG14593-PB", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG14593)", "pathway_count": 1, "publication_count": 15, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;21110953;23293632;24098432;25589440;26020940;26109356;26109357", "class_list": "", "function": "Receptor for the neuropeptide CCHamide-2., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 4, "predicted_n_glycosites": 3, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "A1Z6J7;A9UJU7;E1JGY1", "ec_number_list": "", "go_molecular_function": "GO:0008188 neuropeptide receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway;GO:0007218 neuropeptide signaling pathway", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "Q4V622-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9NII1-1", "uniprot_id": "ADAR_DROME", "mass": 74114.0, "length": 669, "protein_name": "Double-stranded RNA-specific editase Adar", "gene_name": "Adar", "organism": "Fruit fly", "refseq_name": "adenosine deaminase acting on RNA, isoform I", "refseq_ac": "NP_001245469", "gene_names_uniprotkb": "Adar; ADAR1; ADAR; CG12598; Dmel\\CG12598; Dmel_CG12598; EG:BACN35H14.1; adar; adr; cg12598; dADAR; dAdar; dadar; hypnos-2", "gene_names_refseq": "ADAR1; ADAR; Adar; CG12598; Dmel\\CG12598; EG:BACN35H14.1; adar; adr; cg12598; dADAR; dAdar; dadar; hypnos-2", "protein_names_uniprotkb": "Double-stranded RNA-specific editase Adar; 3.5.4.-; Adenosine deaminase that act on RNA; Pre-mRNA adenosine deaminase; RNA-editing deaminase 1; RNA-editing enzyme 1; dADAR; dsRNA adenosine deaminase", "protein_names_refseq": "Adar-PI; CG12598-PI; adenosine deaminase acting on RNA, isoform I; adenosine deaminase acting on rna; adenosine deaminases acting on RNA; hypnos-2; hypoxia, anoxia, sensitive 2", "tax_id": 7227, "disease": "transient cerebral ischemia (Disease Ontology:DOID:224); amyotrophic lateral sclerosis (Disease Ontology:DOID:332); obesity (Disease Ontology:DOID:9970)", "pathway": " (dme:Dmel_CG12598); (R-DME-75102); (R-DME-77042)", "pathway_count": 3, "publication_count": 16, "publication_id_list": "10731132;10731137;10917596;10966106;11254668;12537568;12537572;12537573;12537574;12756328;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "Has A-to-I RNA editing activity on extended dsRNA: edits RNA-binding protein Rnp4F. A-to-I editing of pre-mRNAs acts predominantly through nervous system targets to affect adult nervous system integrity, function and behavior. Essential for adaptation to environmental stresses, such as oxygen deprivation, and for the prevention of premature neuronal degeneration, through the editing of ion channels as targets., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "M9NEQ7;M9NFQ6;M9NGI0;O96834;Q8IRX2;Q8MSQ9;Q9BJ37;Q9NII2;Q9W562;X2JHZ2", "ec_number_list": "3.5.4.-;3.5.4.4;3.5.4.37", "go_molecular_function": "GO:0008251 tRNA-specific adenosine deaminase activity;GO:0046872 metal ion binding;GO:0003725 double-stranded RNA binding;GO:0003726 double-stranded RNA adenosine deaminase activity;GO:0003723 RNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005730 nucleolus;GO:0005737 cytoplasm", "go_biological_process": "GO:0008049 male courtship behavior;GO:0006396 RNA processing;GO:0006397 mRNA processing;GO:0006979 response to oxidative stress;GO:0007283 spermatogenesis", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "Q9NII1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q8SY41-1", "uniprot_id": "BCAS3_DROME", "mass": 117535.0, "length": 1122, "protein_name": "Breast carcinoma-amplified sequence 3 homolog", "gene_name": "rudhira", "organism": "Fruit fly", "refseq_name": "rudhira, isoform D", "refseq_ac": "NP_001245631", "gene_names_uniprotkb": "rudhira; CG1905; CG32662; CG32663; CG43154; DRudh; Dmel\\CG43154; Dmel_CG43154; Drudh; Rudh; anon-EST:Liang-2.41; clone 2.41", "gene_names_refseq": "CG1905; CG32662; CG32663; CG43154; DRudh; Dmel\\CG43154; Drudh; Rudh; anon-EST:Liang-2.41; clone 2.41; rudhira", "protein_names_uniprotkb": "Breast carcinoma-amplified sequence 3 homolog; DRudh; Protein rudhira", "protein_names_refseq": "CG43154-PD; rudhira, isoform D; rudhira-PD", "tax_id": 7227, "disease": "Hengel-Maroofian-Schols syndrome (Disease Ontology:DOID:0070408); breast cancer (Disease Ontology:DOID:1612)", "pathway": " (dme:Dmel_CG43154)", "pathway_count": 1, "publication_count": 18, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16099728;16110336;17372656;17569856;17569867;18060846;18327897;18355807;25589440;26109356;26109357;40245499", "class_list": "", "function": "Regulates macropinocytosis in pericardial cells., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 7, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 7, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 7, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 2, "glyco_site_count": 8, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0042594 response to starvation;GO:0006914 autophagy;GO:0044351 macropinocytosis", "synthesized_glycan_count": 0, "hit_score": 2.7, "record_id": "Q8SY41-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P34021-1", "uniprot_id": "ECR_DROME", "mass": 93853.0, "length": 878, "protein_name": "Ecdysone receptor", "gene_name": "EcR", "organism": "Fruit fly", "refseq_name": "ecdysone receptor, isoform G", "refseq_ac": "NP_001163061", "gene_names_uniprotkb": "EcR; CG1765; CG8347; DEcR; Dhr23; DmEcR; Dmel\\CG1765; Dmel_CG1765; ECR-C; ECR; EcR-A; EcR-B1; EcR-B; EcR1b; EcRA; EcRB-1; EcRB1; EcRB; EcRC; EcdR; Ecr1B; EcrB1; Ecr; NR1H1; USP; Usp; anon-WO0229075.1; dECR; dmEcR; ecr; lie; ms(2)06410; ms(2)42A; snt", "gene_names_refseq": "CG1765; CG8347; DEcR; Dhr23; DmEcR; Dmel\\CG1765; ECR-C; ECR; EcR-A; EcR-B1; EcR-B; EcR1b; EcRA; EcRB-1; EcRB1; EcRB; EcRC; EcR; EcdR; Ecr1B; EcrB1; Ecr; NR1H1; USP; Usp; anon-WO0229075.1; dECR; dmEcR; ecr; lie; ms(2)06410; ms(2)42A; snt", "protein_names_uniprotkb": "Ecdysone receptor; 20-hydroxy-ecdysone receptor; 20E receptor; EcRH; Ecdysteroid receptor B1; Nuclear receptor subfamily 1 group H member 1", "protein_names_refseq": "CG1765-PG; EcR-PG; Ecdysone-R; ecdyson receptor 1b; ecdysone receptor complex; ecdysone receptor, isoform G; ecdysone-Receptor; ecdysteroid receptor; ecdysterone receptor; long island expressway; male sterile(2)42A; snaggletooth", "tax_id": 7227, "disease": "metabolic dysfunction and alcohol associated liver disease (Disease Ontology:DOID:0070508); pre-eclampsia (Disease Ontology:DOID:10591); carotid stenosis (Disease Ontology:DOID:13001); atherosclerosis (Disease Ontology:DOID:1936); coronary artery disease (Disease Ontology:DOID:3393); cerebral infarction (Disease Ontology:DOID:3526); ovarian hyperstimulation syndrome (Disease Ontology:DOID:5425); myocardial infarction (Disease Ontology:DOID:5844); cerebrovascular disease (Disease Ontology:DOID:6713); abdominal aortic aneurysm (Disease Ontology:DOID:7693); type 2 diabetes mellitus (Disease Ontology:DOID:9352); obesity (Disease Ontology:DOID:9970)", "pathway": " (dme:Dmel_CG1765); (R-DME-159418); (R-DME-383280); (R-DME-4090294); (R-DME-8866427); (R-DME-9029569); (R-DME-9623433)", "pathway_count": 7, "publication_count": 20, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;14603321;15996653;16110336;17569856;17569867;1913820;25589440;26109356;26109357;28366641;30293839;8223281;8247157;8324824", "class_list": "", "function": "Receptor for ecdysone (PubMed:1913820, PubMed:30293839). Binds to ecdysone response elements (ECRES) following ecdysone-binding, and recruitment of a complex containing the histone methyltransferase trr; leads to transcriptional activation of target genes (PubMed:1913820, PubMed:30293839)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 12, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q0E9N8;Q6AWL4;Q8SY10;Q95TS4;Q9V9K8", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0005102 signaling receptor binding;GO:0008270 zinc ion binding;GO:0042803 protein homodimerization activity;GO:0046982 protein heterodimerization activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0030425 dendrite;GO:0090575 RNA polymerase II transcription regulator complex;GO:0008230 ecdysone receptor holocomplex", "go_biological_process": "GO:0040034 regulation of development, heterochronic;GO:0043457 regulation of cellular respiration;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 2.1, "record_id": "P34021-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q24048-1", "uniprot_id": "ATPB2_DROME", "mass": 37283.0, "length": 323, "protein_name": "Sodium/potassium-transporting ATPase subunit beta-2", "gene_name": "nrv2", "organism": "Fruit fly", "refseq_name": "nervana 2, isoform F", "refseq_ac": "NP_001014475", "gene_names_uniprotkb": "nrv2; 42kDa; CG9261; Dmel\\CG9261; Dmel_CG9261; K-ATPase; K[+] ATPase; K[+]-ATPase; K[+]ATPase; NEST:bs13c10; NaK ATPase; Na; Nrv2.2; Nrv2; Nrv; ecta; l(2)SH0329; l(2)SH2 0329; l(2)k04223; l(2)k13315; nrv2.2", "gene_names_refseq": "42kDa; CG9261; Dmel\\CG9261; K-ATPase; NEST:bs13c10; NaK ATPase; Na[+]/K[+] ATPase; Na[+]/K[+]-ATPase; Na[+]/K[+]ATPase; Na; Nrv2.2; Nrv2; Nrv; ecta; l(2)SH0329; l(2)SH2 0329; l(2)k04223; l(2)k13315; nrv2.2; nrv2", "protein_names_uniprotkb": "Sodium/potassium-transporting ATPase subunit beta-2; Protein nervana 2; Sodium/potassium-dependent ATPase subunit beta-2", "protein_names_refseq": "CG9261-PF; Na+/K+ ATPase; Na,K-ATPase beta-subunit; Na[+]/K[+] ATPase; ectatic; nervana 2, isoform F; nervana 2; nervana2; nirvana2; nirvana; nrv2-PF", "tax_id": 7227, "disease": "autoimmune gastritis (Disease Ontology:DOID:0040090); sensorineural hearing loss (Disease Ontology:DOID:10003); stomach cancer (Disease Ontology:DOID:10534); essential hypertension (Disease Ontology:DOID:10825); epilepsy (Disease Ontology:DOID:1826); atrophic gastritis (Disease Ontology:DOID:8929); obesity (Disease Ontology:DOID:9970)", "pathway": " (dme:Dmel_CG9261); (R-DME-210991); (R-DME-2173795)", "pathway_count": 3, "publication_count": 16, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;17893096;25589440;26109356;26109357;7540667;7777518;9648860", "class_list": "", "function": "This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane., [UniProtKB, PubMed, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 1, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 1, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 1, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 7, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "Q24047;Q9VM84;Q9VM85", "ec_number_list": "", "go_molecular_function": "GO:0001671 ATPase activator activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0030424 axon;GO:0005890 sodium:potassium-exchanging ATPase complex;GO:0005918 septate junction", "go_biological_process": "GO:0006812 monoatomic cation transport;GO:0006883 intracellular sodium ion homeostasis;GO:0007605 sensory perception of sound;GO:0030007 intracellular potassium ion homeostasis;GO:0036376 sodium ion export across plasma membrane", "synthesized_glycan_count": 0, "hit_score": 1.8, "record_id": "Q24048-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P54733-1", "uniprot_id": "CCNE_DROME", "mass": 77221.0, "length": 709, "protein_name": "G1/S-specific cyclin-E", "gene_name": "CycE", "organism": "Fruit fly", "refseq_name": "cyclin E, isoform A", "refseq_ac": "NP_476959", "gene_names_uniprotkb": "CycE; 3938; BG:DS07108.3; CDI7; CG3938; CYCE; Cdi7; CyE-1; Cyc E; Cyc-E; CycEI; CyclE; Cyc; CyeE; D-CycE; DmCycE; DmcycE; DmcyclinE; Dmel\\CG3938; Dmel_CG3938; br37; cdi7; cycE; cyclin E; cyclin-E; cyclinE; cycline; dCycE; dm-cycE; fond; l(2)05206; l(2)35Dd; l(2)br37; l(2)k02514; l(2)k02602; l(2)k05007; l35Dd", "gene_names_refseq": "3938; BG:DS07108.3; CDI7; CG3938; CYCE; Cdi7; CyE-1; Cyc E; Cyc-E; CycEI; CycE; CyclE; Cyc; CyeE; D-CycE; DmCycE; DmcycE; DmcyclinE; Dmel\\CG3938; br37; cdi7; cycE; cyclin E; cyclin-E; cyclinE; cycline; dCycE; dm-cycE; fond; l(2)05206; l(2)35Dd; l(2)br37; l(2)k02514; l(2)k02602; l(2)k05007; l35Dd", "protein_names_uniprotkb": "G1/S-specific cyclin-E; DmCycE", "protein_names_refseq": "CG3938-PA; CycE-PA; Cyclin-dependent kinase interactor 7; cyclin E, isoform A; cyclin E; cyclin-E; cyclinE; cycline E; dCyclinE; fondue", "tax_id": 7227, "disease": "castration-resistant prostate carcinoma (Disease Ontology:DOID:0080909); prostate cancer (Disease Ontology:DOID:10283); hypertension (Disease Ontology:DOID:10763); urinary bladder cancer (Disease Ontology:DOID:11054); breast cancer (Disease Ontology:DOID:1612); cancer (Disease Ontology:DOID:162); breast adenocarcinoma (Disease Ontology:DOID:3458); liver cancer (Disease Ontology:DOID:3571); lung non-small cell carcinoma (Disease Ontology:DOID:3908); ovarian carcinoma (Disease Ontology:DOID:4001); renal cell carcinoma (Disease Ontology:DOID:4450); hepatocellular carcinoma (Disease Ontology:DOID:684); cervix uteri carcinoma in situ (Disease Ontology:DOID:8991)", "pathway": " (dme:Dmel_CG3938); (R-DME-1538133); (R-DME-187577); (R-DME-2559586); (R-DME-6804116); (R-DME-69017); (R-DME-69200); (R-DME-69202); (R-DME-69231); (R-DME-69563)", "pathway_count": 10, "publication_count": 17, "publication_id_list": "10471707;10731132;11565033;12537568;12537569;12537572;12537573;12537574;16110336;17431409;17569856;17569867;18327897;25589440;26109356;26109357;8187637", "class_list": "", "function": "Essential for the control of the cell cycle at the G1/S (start) transition. Targeted by archipelago for degradation by the SFC ubiquitin ligase complex., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 9, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 13, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q24479;Q95RP5;Q9V3B3;Q9V456", "ec_number_list": "", "go_molecular_function": "GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005815 microtubule organizing center;GO:0097134 cyclin E1-CDK2 complex", "go_biological_process": "GO:0042127 regulation of cell population proliferation;GO:0043065 positive regulation of apoptotic process;GO:0007422 peripheral nervous system development;GO:0000082 G1/S transition of mitotic cell cycle;GO:0006275 regulation of DNA replication", "synthesized_glycan_count": 0, "hit_score": 1.8, "record_id": "P54733-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9NB04-1", "uniprot_id": "PATJ_DROME", "mass": 92852.0, "length": 871, "protein_name": "Patj homolog", "gene_name": "Patj", "organism": "Fruit fly", "refseq_name": "patj, isoform C", "refseq_ac": "NP_477342", "gene_names_uniprotkb": "Patj; BcDNA:LD22238; CG12021; D-Patj; DLT; DPATJ; DPatj; Dlt; Dmel\\CG12021; Dmel_CG12021; Dpatj; PATJ; PaTJ; PatJ; dPATJ; dPatj; dlt:discs lost; dlt; dpatj; patj", "gene_names_refseq": "BcDNA:LD22238; CG12021; D-Patj; DLT; DPATJ; DPatj; Dlt; Dmel\\CG12021; Dpatj; PATJ; PaTJ; PatJ; Patj/Dlt; Patj; dPATJ; dPatj; dlt:discs lost; dlt; dpatj; patj", "protein_names_uniprotkb": "Patj homolog", "protein_names_refseq": "CG12021-PC; Patj-PC; discs lost; discslost; patj, isoform C", "tax_id": 7227, "disease": "hydrocephalus (Disease Ontology:DOID:10908)", "pathway": " (dme:Dmel_CG12021); (R-DME-983168)", "pathway_count": 2, "publication_count": 21, "publication_id_list": "10102271;10731132;11076972;11740560;12537568;12537569;12537572;12537573;12537574;12900452;14667407;16110336;17569856;17569867;18327897;25589440;26109356;26109357;33925313;37086384;40245499", "class_list": "", "function": "Involved in cell polarity establishment. Probably participates in the assembly, positioning and maintenance of adherens junctions via its interaction with the SAC complex., [UniProtKB, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 6, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 6, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 6, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 1, "glyco_site_count": 7, "binding_glycan_count": 0, "secondary_ac_list": "Q9UA56;Q9XZ35", "ec_number_list": "", "go_molecular_function": "GO:0017020 myosin phosphatase regulator activity;GO:0005080 protein kinase C binding;GO:0032033 myosin II light chain binding", "go_cellular_component": "GO:0045179 apical cortex;GO:0005635 nuclear envelope;GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0005912 adherens junction", "go_biological_process": "GO:0016332 establishment or maintenance of polarity of embryonic epithelium;GO:0045494 photoreceptor cell maintenance;GO:0007043 cell-cell junction assembly;GO:0034332 adherens junction organization;GO:0034334 adherens junction maintenance", "synthesized_glycan_count": 0, "hit_score": 2.9, "record_id": "Q9NB04-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q24207-1", "uniprot_id": "BOULE_DROME", "mass": 24682.0, "length": 228, "protein_name": "Protein boule", "gene_name": "bol", "organism": "Fruit fly", "refseq_name": "boule, isoform G", "refseq_ac": "NP_001286992", "gene_names_uniprotkb": "bol; BOL; BcDNA:AT13332; Bol; Boule; CG4727; CG4760; Dmel\\CG4760; Dmel_CG4760; lincRNA.485; ms(3)07272", "gene_names_refseq": "BOL; BcDNA:AT13332; Bol; Boule; CG4727; CG4760; Dmel\\CG4760; bol; lincRNA.485; ms(3)07272", "protein_names_uniprotkb": "Protein boule", "protein_names_refseq": "CG4760-PG; bol-PG; boule, isoform G; boule", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG4760)", "pathway_count": 1, "publication_count": 17, "publication_id_list": "10559904;10731132;12499397;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;23209437;25589440;26109356;26109357;8657280;9882490", "class_list": "", "function": "RNA-binding protein that plays a central role in spermatogenesis. Required for meiotic entry and germline differentiation, at the transition between G2 and M phases of meiosis I. Acts by regulating translation of specific mRNAs, possibly by binding to their 3'-UTR. Essential for translation of twine (twe) mRNA. Required for the expression of various genes such as CG6784, CG17210, CG15841 scpr-B, scpr-C, and rho-6., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q8T472;Q9VSU4;Q9VSU5", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding;GO:0003729 mRNA binding;GO:0008494 translation activator activity;GO:0003730 mRNA 3'-UTR binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0043204 perikaryon", "go_biological_process": "GO:0006417 regulation of translation;GO:0030154 cell differentiation;GO:0070935 3'-UTR-mediated mRNA stabilization;GO:0045948 positive regulation of translational initiation;GO:0045924 regulation of female receptivity", "synthesized_glycan_count": 0, "hit_score": 1.8, "record_id": "Q24207-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P39413-1", "uniprot_id": "AEF1_DROME", "mass": 33782.0, "length": 308, "protein_name": "Adult enhancer factor 1", "gene_name": "Aef1", "organism": "Fruit fly", "refseq_name": "adult enhancer factor 1, isoform B", "refseq_ac": "NP_524200", "gene_names_uniprotkb": "Aef1; AEF-1; AEF1; CG5683; Dmel\\CG5683; Dmel_CG5683; aef1", "gene_names_refseq": "AEF-1; AEF1; Aef1; CG5683; Dmel\\CG5683; aef1", "protein_names_uniprotkb": "Adult enhancer factor 1; AEF-1", "protein_names_refseq": "Adh enhancer factor 1; Aef1-PB; CG5683-PB; adult enhancer factor 1, isoform B", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG5683)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;1508206;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "Transcriptional repressor that binds specifically to fat body-specific enhancers, namely the adult ADH enhancer (AAE) and the enhancer that controls yolk protein gene expression., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q0E8C4;Q9VP37", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "P39413-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P15364-1", "uniprot_id": "AMAL_DROME", "mass": 36387.0, "length": 333, "protein_name": "Protein amalgam", "gene_name": "Ama", "organism": "Fruit fly", "refseq_name": "amalgam, isoform A", "refseq_ac": "NP_476579", "gene_names_uniprotkb": "Ama; AMA; BG:DS00276.6; CG2198; CT7244; Dmel\\CG2198; Dmel_CG2198; M109; ama", "gene_names_refseq": "AMA; Ama; BG:DS00276.6; CG2198; CT7244; Dmel\\CG2198; M109; ama", "protein_names_uniprotkb": "Protein amalgam", "protein_names_refseq": "Ama-PA; CG2198-PA; amalgam shotgun; amalgam, isoform A; amalgam", "tax_id": 7227, "disease": "primary open angle glaucoma (Disease Ontology:DOID:1070); hypertension (Disease Ontology:DOID:10763); uterine fibroid (Disease Ontology:DOID:13223); ovary epithelial cancer (Disease Ontology:DOID:2152); ovarian cancer (Disease Ontology:DOID:2394); congestive heart failure (Disease Ontology:DOID:6000)", "pathway": " (dme:Dmel_CG2198)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357;3141062", "class_list": "", "function": "", "predicted_glycosites": 4, "predicted_n_glycosites": 3, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 6, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "Q9V3A5", "ec_number_list": "", "go_molecular_function": "GO:0048018 receptor ligand activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005886 plasma membrane;GO:0098552 side of membrane", "go_biological_process": "GO:0060252 positive regulation of glial cell proliferation;GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway;GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0035633 maintenance of blood-brain barrier;GO:1903977 positive regulation of glial cell migration", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "P15364-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P22058-1", "uniprot_id": "CPD1_DROME", "mass": 37000.0, "length": 355, "protein_name": "Chromosomal protein D1", "gene_name": "D1", "organism": "Fruit fly", "refseq_name": "D1 chromosomal protein, isoform A", "refseq_ac": "NP_524286", "gene_names_uniprotkb": "D1; CG9745; Dmel\\CG9745; Dmel_CG9745; EP(3)0473; HMGI; RE69409; dD1; dHMGx", "gene_names_refseq": "CG9745; D1; Dmel\\CG9745; EP(3)0473; HMGI; RE69409; dD1; dHMGx", "protein_names_uniprotkb": "Chromosomal protein D1", "protein_names_refseq": "CG9745-PA; D1 chromosomal protein, isoform A; D1-PA; chromosomal protein D1", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG9745)", "pathway_count": 1, "publication_count": 15, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17372656;17569856;17569867;18327897;2542275;25589440;26109356;26109357", "class_list": "", "function": "This satellite DNA-associated protein is a double-stranded DNA binding protein specific for tracts of pure at DNA. It may play a role in organizing the higher-order structure of euchromatin as well as heterochromatin., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 26, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q24215;Q8SX69;Q9VHH3", "ec_number_list": "", "go_molecular_function": "GO:0003680 minor groove of adenine-thymine-rich DNA binding;GO:0003696 satellite DNA binding;GO:0003677 DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0000792 heterochromatin;GO:0000786 nucleosome;GO:0005700 polytene chromosome", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "P22058-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P49071-1", "uniprot_id": "MAPK2_DROME", "mass": 41401.0, "length": 359, "protein_name": "MAP kinase-activated protein kinase 2", "gene_name": "MAPk-Ak2", "organism": "Fruit fly", "refseq_name": "MAP kinase activated protein-kinase-2, isoform E", "refseq_ac": "NP_001188547", "gene_names_uniprotkb": "MAPk-Ak2; CG3086; DmMAPKAPK-2; Dmel\\CG3086; Dmel_CG3086; MAPKAPK-2; MAPKAP; MK2; dMK2", "gene_names_refseq": "CG3086; DmMAPKAPK-2; Dmel\\CG3086; MAPKAPK-2; MAPKAP; MAPk-Ak2; MK2; dMK2", "protein_names_uniprotkb": "MAP kinase-activated protein kinase 2; 2.7.11.1; MAPK-activated protein kinase 2; MAPKAP kinase 2; MAPKAPK-2", "protein_names_refseq": "CG3086-PE; MAP kinase activated protein kinase-2; MAP kinase activated protein-kinase-2, isoform E; MAP kinase-activated protein kinase 2; MAPk-Ak2-PE", "tax_id": 7227, "disease": "patterned macular dystrophy 3 (Disease Ontology:DOID:0060865)", "pathway": " (dme:Dmel_CG3086); (R-DME-171007); (R-DME-199920); (R-DME-2559580); (R-DME-3371453); (R-DME-4420097); (R-DME-450302); (R-DME-450385); (R-DME-450513)", "pathway_count": 9, "publication_count": 12, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357;7590268", "class_list": "", "function": "Its physiological substrate seems to be the small heat shock protein (HSP27/HSP25)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9W480", "ec_number_list": "2.7.11.17;2.7.11.1;2.7.11.13;2.7.11.24;2.7.11.22;2.7.12.2;2.7.11.21;5.6.1.8;3.6.4.-;2.7.11.11;2.7.11.23;2.7.12.1;2.7.11.25;2.7.11.12;2.7.10.2;2.3.2.27;2.7.11.39", "go_molecular_function": "GO:0009931 calcium-dependent protein serine/threonine kinase activity;GO:0004672 protein kinase activity;GO:0005516 calmodulin binding;GO:0005524 ATP binding;GO:0051019 mitogen-activated protein kinase binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0035556 intracellular signal transduction;GO:0009651 response to salt stress;GO:0045793 positive regulation of cell size;GO:0046328 regulation of JNK cascade;GO:1902957 negative regulation of mitochondrial electron transport, NADH to ubiquinone", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "P49071-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9NBW1-1", "uniprot_id": "FRIZ4_DROME", "mass": 77490.0, "length": 705, "protein_name": "Frizzled-4", "gene_name": "fz4", "organism": "Fruit fly", "refseq_name": "frizzled 4, isoform A", "refseq_ac": "NP_511068", "gene_names_uniprotkb": "fz4; CG4626; DFz4; Dfz4; Dm Fz4; Dmel\\CG4626; Dmel_CG4626; Fz4; anon-WO0170980.10; anon-WO0170980.11", "gene_names_refseq": "CG4626; DFz4; Dfz4; Dm Fz4; Dmel\\CG4626; Fz4; anon-WO0170980.10; anon-WO0170980.11; fz4", "protein_names_uniprotkb": "Frizzled-4; dFz4", "protein_names_refseq": "CG4626-PA; Frizzled4; frizzled 4, isoform A; frizzled 4; fz4-PA", "tax_id": 7227, "disease": "exudative vitreoretinopathy (Disease Ontology:DOID:0050535); Norrie disease (Disease Ontology:DOID:0060844); exudative vitreoretinopathy 1 (Disease Ontology:DOID:0111412); prostate carcinoma in situ (Disease Ontology:DOID:8634)", "pathway": " (dme:Dmel_CG4626)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. Required to coordinate the cytoskeletons of epidermal cells to produce a parallel array of cuticular hairs and bristles., [UniProtKB]", "predicted_glycosites": 4, "predicted_n_glycosites": 4, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "Q9W3S2", "ec_number_list": "", "go_molecular_function": "GO:0004888 transmembrane signaling receptor activity;GO:0004930 G protein-coupled receptor activity;GO:0017147 Wnt-protein binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0016020 membrane", "go_biological_process": "GO:0007165 signal transduction;GO:0060070 canonical Wnt signaling pathway;GO:0035567 non-canonical Wnt signaling pathway;GO:0016055 Wnt signaling pathway", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "Q9NBW1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P27619-1", "uniprot_id": "DYN_DROME", "mass": 97809.0, "length": 877, "protein_name": "Dynamin", "gene_name": "shi", "organism": "Fruit fly", "refseq_name": "shibire, isoform H", "refseq_ac": "NP_001036278", "gene_names_uniprotkb": "shi; CG18102; DNM3; DYN; Ddyn3; Ddyn4; Ddyn; Dmel\\CG18102; Dmel_CG18102; Dynamin; Dyn; Shibire; Shi; Vps1; anon-WO0153538.12; anon-WO0153538.13; anon-WO0153538.14; dDyn; dynamin; dyn; l(1)VII; l(1)shi; shibere; shib; shu", "gene_names_refseq": "CG18102; DNM3; DYN; Ddyn3; Ddyn4; Ddyn; Dmel\\CG18102; Dynamin; Dyn; Shibire; Shi; Vps1; anon-WO0153538.12; anon-WO0153538.13; anon-WO0153538.14; dDyn; dynamin; dyn; l(1)VII; l(1)shi; shibere; shib; shi; shu", "protein_names_uniprotkb": "Dynamin; 3.6.5.5; Protein shibire; dDyn", "protein_names_refseq": "CG18102-PH; dynamin; shi-PH; shibere; shibire, isoform H; shibire; shibiri", "tax_id": 7227, "disease": "lethal congenital contracture syndrome (Disease Ontology:DOID:0060558); developmental and epileptic encephalopathy 31B (Disease Ontology:DOID:0070376); developmental and epileptic encephalopathy 31A (Disease Ontology:DOID:0080437); Charcot-Marie-Tooth disease dominant intermediate B (Disease Ontology:DOID:0110197); centronuclear myopathy 1 (Disease Ontology:DOID:0111223); Alzheimer's disease (Disease Ontology:DOID:10652); microcytic anemia (Disease Ontology:DOID:11252); centronuclear myopathy (Disease Ontology:DOID:14717); generalized epilepsy (Disease Ontology:DOID:1827); cystic kidney disease (Disease Ontology:DOID:2975); myopathy (Disease Ontology:DOID:423); collagen disease (Disease Ontology:DOID:854)", "pathway": " (dme:Dmel_CG18102); (R-DME-190873); (R-DME-196025); (R-DME-3928665); (R-DME-432720); (R-DME-432722); (R-DME-437239); (R-DME-8856828)", "pathway_count": 8, "publication_count": 14, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;1674590;17569856;17569867;1828536;18327897;25589440;26109356;26109357", "class_list": "", "function": "Microtubule-associated force-producing protein which is involved in the production of microtubule bundles and which is able to bind and hydrolyze GTP. Implicated in endocytic protein sorting., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 12, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q0KHS4;Q9VXM2", "ec_number_list": "3.6.5.5;3.6.5.2;3.6.5.-;3.1.3.56;2.7.10.1;3.6.4.-;3.6.5.3;3.1.22.1;2.3.2.27", "go_molecular_function": "GO:0003779 actin binding;GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0008017 microtubule binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005874 microtubule;GO:0005886 plasma membrane;GO:0031594 neuromuscular junction;GO:0045202 synapse", "go_biological_process": "GO:0048172 regulation of short-term neuronal synaptic plasticity;GO:0006897 endocytosis;GO:0007612 learning;GO:0007613 memory;GO:0030198 extracellular matrix organization", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "P27619-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9TW27-1", "uniprot_id": "Q9TW27_DROME", "mass": 44642.0, "length": 410, "protein_name": "DISCO interacting protein 1, isoform D", "gene_name": "DIP1", "organism": "Fruit fly", "refseq_name": "DISCO interacting protein 1, isoform D", "refseq_ac": "NP_728449", "gene_names_uniprotkb": "DIP1; CG17686; Dmel\\CG17686; Dmel_CG17686; TO34; TO67; UbxBP1; clot 10495; clot 2020; dip1a; dip1; klt", "gene_names_refseq": "CG17686; DIP1; Dmel\\CG17686; TO34; TO67; UbxBP1; clot 10495; clot 2020; dip1a; dip1; klt", "protein_names_uniprotkb": "DISCO interacting protein 1, isoform D", "protein_names_refseq": "CG17686-PD; DIP1-PD; DISCO interacting protein 1, isoform D; Disco-interacting protein 1; Disconnected-interacting protein 1; disconnected interacting protein 1; klett; ultrabithorax binding protein 1", "tax_id": 7227, "disease": "", "pathway": " (R-DME-203927); (R-DME-426486); (R-DME-9833482)", "pathway_count": 3, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003725 double-stranded RNA binding;GO:0097157 pre-mRNA intronic binding;GO:0035197 siRNA binding;GO:0070883 pre-miRNA binding;GO:0106222 lncRNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0016604 nuclear body;GO:0016442 RISC complex;GO:0070578 RISC-loading complex", "go_biological_process": "GO:0051607 defense response to virus;GO:0010468 regulation of gene expression;GO:0098586 cellular response to virus;GO:0030422 siRNA processing;GO:1990261 pre-mRNA catabolic process", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9TW27-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P40795-1", "uniprot_id": "FOG_DROME", "mass": 78251.0, "length": 730, "protein_name": "Protein folded gastrulation", "gene_name": "fog", "organism": "Fruit fly", "refseq_name": "folded gastrulation, isoform B", "refseq_ac": "NP_001033860", "gene_names_uniprotkb": "fog; 114; CG9559; CR41108; CR41109; CR41110; Dmel\\CG9559; Dmel_CG9559; Fog; M67; l(1)114; l(1)16-3-190; l(1)20Ba; l114", "gene_names_refseq": "114; CG9559; CR41108; CR41109; CR41110; Dmel\\CG9559; Fog; M67; fog; l(1)114; l(1)16-3-190; l(1)20Ba; l114", "protein_names_uniprotkb": "Protein folded gastrulation", "protein_names_refseq": "CG9559-PB; fog-PB; folded gastrulation, isoform B; folded gastrulation", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG9559)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357;8137424", "class_list": "", "function": "Coordinates cell shape changes during formation of the ventral furrow and invagination of the posterior midgut primordium, by inducing apical constriction of cells in spatially and temporally defined manners. Could function as a secreted signal to initiate apical constriction by acting as a ligand for an unidentified G protein-coupled receptor, which in turn activates the G protein alpha subunit encoded by concertina, in neighboring cells. Such an intracellular pathway would ultimately induce contraction of the apical actin-myosin network. In the ventral furrow, fog appears to ensure that all the cells initiate constriction within several minutes of each other. In the posterior midgut invagination, fog appears to direct the ordered progression of constriction initiations out from a central region and also to delimit the peripheral extent of this spreading., [UniProtKB, PubMed]", "predicted_glycosites": 9, "predicted_n_glycosites": 8, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 9, "binding_glycan_count": 0, "secondary_ac_list": "Q9VR71", "ec_number_list": "", "go_molecular_function": "GO:0001664 G protein-coupled receptor binding;GO:0048018 receptor ligand activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005737 cytoplasm", "go_biological_process": "GO:0040034 regulation of development, heterochronic;GO:0021782 glial cell development;GO:0007186 G protein-coupled receptor signaling pathway;GO:0007399 nervous system development;GO:0016331 morphogenesis of embryonic epithelium", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "P40795-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P29776-1", "uniprot_id": "ETS6_DROME", "mass": 51802.0, "length": 475, "protein_name": "DNA-binding protein D-ETS-6", "gene_name": "Ets21C", "organism": "Fruit fly", "refseq_name": "Ets at 21C, isoform C", "refseq_ac": "NP_001285547", "gene_names_uniprotkb": "Ets21C; CG2914; D-Ets-6; D-Ets6; D-ets-6; Dmel\\CG2914; Dmel_CG2914; ETS-6; ETS6; Ets21c; Ets6; Ets; ets21C; ets21c", "gene_names_refseq": "CG2914; D-Ets-6; D-Ets6; D-ets-6; Dmel\\CG2914; ETS6; Ets21C; Ets21c; Ets6; Ets; ets21C; ets21c", "protein_names_uniprotkb": "DNA-binding protein D-ETS-6", "protein_names_refseq": "CG2914-PC; Ets at 21C, isoform C; Ets21C-PC", "tax_id": 7227, "disease": "limb ischemia (Disease Ontology:DOID:0050852); thrombocytopenia (Disease Ontology:DOID:1588); blood platelet disease (Disease Ontology:DOID:2218); systemic scleroderma (Disease Ontology:DOID:418)", "pathway": " (dme:Dmel_CG2914); (R-DME-2559585)", "pathway_count": 2, "publication_count": 12, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;1577186;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "Q9VPQ9", "ec_number_list": "", "go_molecular_function": "GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0043565 sequence-specific DNA binding;GO:0003700 DNA-binding transcription factor activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0030154 cell differentiation;GO:0042742 defense response to bacterium", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "P29776-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P15278-1", "uniprot_id": "FAS3_DROME", "mass": 55884.0, "length": 508, "protein_name": "Fasciclin-3", "gene_name": "Fas3", "organism": "Fruit fly", "refseq_name": "fasciclin 3, isoform F", "refseq_ac": "NP_001286039", "gene_names_uniprotkb": "Fas3; CG5803; Dmel\\CG5803; Dmel_CG5803; FAS III; FAS3; FASIII; Fas III; Fas-3; Fas-III; FasIII; FascIII; Fas; fas III; fas-III; fas3; fasIII; fascIII", "gene_names_refseq": "CG5803; Dmel\\CG5803; FAS III; FAS3; FASIII; Fas III; Fas-3; Fas-III; Fas3; FasIII; FascIII; Fas; fas III; fas-III; fas3; fasIII; fascIII", "protein_names_uniprotkb": "Fasciclin-3; FAS III; Fasciclin III", "protein_names_refseq": "CG5803-PF; Fas3-PF; Fasciclin-3; Fasciclin-III; Fasciclin3; FasciclinIII; FsciclinIII; fascicilin III; fasciclin 3, isoform F; fasciclin 3; fasciclin III; fasciclin; fascilin III; fasiciclin III; fasicilin III; fasiclin III", "tax_id": 7227, "disease": "autism spectrum disorder (Disease Ontology:DOID:0060041); cleft lip-palate-ectodermal dysplasia syndrome (Disease Ontology:DOID:0060773); prostate cancer (Disease Ontology:DOID:10283); Charcot-Marie-Tooth disease (Disease Ontology:DOID:10595); ectodermal dysplasia (Disease Ontology:DOID:2121); malignant astrocytoma (Disease Ontology:DOID:3069); breast carcinoma (Disease Ontology:DOID:3459); lung adenocarcinoma (Disease Ontology:DOID:3910); cleft palate (Disease Ontology:DOID:674); hepatocellular carcinoma (Disease Ontology:DOID:684); retinoblastoma (Disease Ontology:DOID:768); psoriasis (Disease Ontology:DOID:8893); cervix uteri carcinoma in situ (Disease Ontology:DOID:8991); cleft lip (Disease Ontology:DOID:9296); type 2 diabetes mellitus (Disease Ontology:DOID:9352); obesity (Disease Ontology:DOID:9970)", "pathway": " (dme:Dmel_CG5803); (R-DME-418990); (R-DME-420597)", "pathway_count": 3, "publication_count": 15, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;2509076;25589440;26109356;26109357;37041188;40245499", "class_list": "", "function": "Mediates cell adhesion in a Ca(2+)-independent manner (PubMed:2509076). It plays a role in axon outgrowth, guidance and fasciculation of the developing nervous system (PubMed:2509076). Function in neurons is essential for adult survival, and is important for climbing behavior and activity (PubMed:37041188)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 16, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "Q8SXX9;Q9VJ89", "ec_number_list": "", "go_molecular_function": "GO:0098631 cell adhesion mediator activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005912 adherens junction;GO:0031594 neuromuscular junction;GO:0055037 recycling endosome;GO:0005920 smooth septate junction", "go_biological_process": "GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0007413 axonal fasciculation;GO:0007411 axon guidance;GO:0008039 synaptic target recognition", "synthesized_glycan_count": 0, "hit_score": 1.8, "record_id": "P15278-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q8MSX1-1", "uniprot_id": "ENC_DROME", "mass": 188663.0, "length": 1818, "protein_name": "Protein encore", "gene_name": "enc", "organism": "Fruit fly", "refseq_name": "encore, isoform D", "refseq_ac": "NP_001097496", "gene_names_uniprotkb": "enc; BB129; CG10847; Dmel\\CG10847; Dmel_CG10847; Enc; fs(3)63F-64A", "gene_names_refseq": "BB129; CG10847; Dmel\\CG10847; Enc; enc; fs(3)63F-64A", "protein_names_uniprotkb": "Protein encore", "protein_names_refseq": "CG10847-PD; enc-PD; encore, isoform D; encore", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG10847)", "pathway_count": 1, "publication_count": 17, "publication_id_list": "10731132;11044391;11879639;12537568;12537569;12537572;12537573;12537574;14623823;16110336;17569856;17569867;18327897;25589440;26109356;26109357;9428416", "class_list": "", "function": "Required for the regulation of germline mitosis, karyosome formation, and establishment of dorsoventral (DS) polarity of the egg and embryo. Involved in proper grk mRNA localization and translation in the oocyte. May control germline mitosis by facilitating the cyclin E (CycE) proteolysis by the SCF-ubiquitin-proteasome complex., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A8JNK0;B6IDK9;Q5BIH9;Q7KV61;Q9NGQ6;Q9VZM1", "ec_number_list": "", "go_molecular_function": "GO:0003676 nucleic acid binding", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0048477 oogenesis;GO:0007282 cystoblast division;GO:0048134 germ-line cyst formation;GO:0007293 germarium-derived egg chamber formation;GO:0007294 germarium-derived oocyte fate determination", "synthesized_glycan_count": 0, "hit_score": 1.8, "record_id": "Q8MSX1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P48610-1", "uniprot_id": "KARG_DROME", "mass": 39866.0, "length": 356, "protein_name": "Arginine kinase 1", "gene_name": "Argk1", "organism": "Fruit fly", "refseq_name": "arginine kinase 1, isoform G", "refseq_ac": "NP_001097556", "gene_names_uniprotkb": "Argk1; AK-1; AK1; AK; ARK; ArgK; Argk; CG32031; CG4929; CG5173; Dmel\\CG32031; Dmel_CG32031; KARG; argK; argk", "gene_names_refseq": "AK-1; AK1; AK; ARK; ArgK; Argk1; Argk; CG32031; CG4929; CG5173; Dmel\\CG32031; KARG; argK; argk", "protein_names_uniprotkb": "Arginine kinase 1; 2.7.3.3", "protein_names_refseq": "Argk1-PG; CG32031-PG; arginine kinase 1, isoform G; arginine kinase; insect intestinal mucin iim22", "tax_id": 7227, "disease": "left ventricular failure (Disease Ontology:DOID:0051064); status epilepticus (Disease Ontology:DOID:1824)", "pathway": " (dme:Dmel_CG32031)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q8IQB9;Q8IQC0;Q8T0S2;Q9VST5;Q9VST6", "ec_number_list": "2.7.3.3", "go_molecular_function": "GO:0004111 creatine kinase activity;GO:0005524 ATP binding;GO:0016301 kinase activity;GO:0004054 arginine kinase activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0005615 extracellular space;GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005829 cytosol", "go_biological_process": "GO:0046314 phosphocreatine biosynthetic process;GO:0016310 phosphorylation", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "P48610-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q8IA42-1", "uniprot_id": "GALT4_DROME", "mass": 74040.0, "length": 644, "protein_name": "N-acetylgalactosaminyltransferase 4", "gene_name": "Pgant4", "organism": "Fruit fly", "refseq_name": "polypeptide N-Acetylgalactosaminyltransferase 4, isoform B", "refseq_ac": "NP_001137779", "gene_names_uniprotkb": "Pgant4; CG31956; CG8845b; CG8845; Dmel\\CG31956; Dmel_CG31956; pgant4", "gene_names_refseq": "CG31956; CG8845b; CG8845; Dmel\\CG31956; Pgant4; pgant4", "protein_names_uniprotkb": "N-acetylgalactosaminyltransferase 4; 2.4.1.41; Protein-UDP acetylgalactosaminyltransferase 4; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 4; pp-GaNTase 4", "protein_names_refseq": "CG31956-PB; Pgant4-PB; polypeptide GalNAc transferase 4; polypeptide N-Acetylgalactosaminyltransferase 4, isoform B", "tax_id": 7227, "disease": "depressive disorder (Disease Ontology:DOID:1596)", "pathway": " (dme:Dmel_CG31956); (R-DME-913709)", "pathway_count": 2, "publication_count": 15, "publication_id_list": "10731132;11925450;12537568;12537572;12537573;12537574;12829714;16110336;16251381;17569856;17569867;22157008;25589440;26109356;26109357", "class_list": "", "function": "Glycopeptide transferase involved in O-linked oligosaccharide biosynthesis, which catalyzes the transfer of an N-acetyl-D-galactosamine residue to an already glycosylated peptide. In contrast to other proteins of the family, it does not act as a peptide transferase that transfers GalNAc onto serine or threonine residue on the protein receptor, but instead requires the prior addition of a GalNAc on a peptide before adding additional GalNAc moieties. Some peptide transferase activity is however not excluded, considering that its appropriate peptide substrate may remain unidentified. Prefers the diglycosylated Muc5AC-3/13 as substrate., [UniProtKB, PubMed]", "predicted_glycosites": 5, "predicted_n_glycosites": 5, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "Q8IQ11", "ec_number_list": "2.4.1.-;2.4.1.41", "go_molecular_function": "GO:0046872 metal ion binding;GO:0030246 carbohydrate binding;GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity;GO:0016757 glycosyltransferase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005794 Golgi apparatus;GO:0005795 Golgi stack", "go_biological_process": "GO:0006493 protein O-linked glycosylation;GO:0016266 protein O-linked glycosylation via N-acetyl-galactosamine;GO:0051047 positive regulation of secretion;GO:0033363 secretory granule organization", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "Q8IA42-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q24120-1", "uniprot_id": "CAPU_DROME", "mass": 113864.0, "length": 1059, "protein_name": "Protein cappuccino", "gene_name": "capu", "organism": "Fruit fly", "refseq_name": "cappuccino, isoform A", "refseq_ac": "NP_476966", "gene_names_uniprotkb": "capu; CG15420; CG3399; Capu; Dmel\\CG3399; Dmel_CG3399; capp", "gene_names_refseq": "CG15420; CG3399; Capu; Dmel\\CG3399; capp; capu", "protein_names_uniprotkb": "Protein cappuccino", "protein_names_refseq": "CG3399-PA; cappuccino, isoform A; cappuccino; cappucino; capu-PA", "tax_id": 7227, "disease": "alcohol dependence (Disease Ontology:DOID:0050741); autosomal recessive intellectual developmental disorder 47 (Disease Ontology:DOID:0081211)", "pathway": " (dme:Dmel_CG3399)", "pathway_count": 1, "publication_count": 14, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;19633175;21730168;25589440;26109356;26109357;7590229", "class_list": "", "function": "Acts as an actin nucleation factor and promotes assembly of actin filaments together with spir. May play a role in intracellular vesicle transport along actin fibers, providing a novel link between actin cytoskeleton dynamics and intracellular transport., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 6, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q9VQV8", "ec_number_list": "", "go_molecular_function": "GO:0003779 actin binding;GO:0008017 microtubule binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005884 actin filament;GO:0005938 cell cortex;GO:0030659 cytoplasmic vesicle membrane", "go_biological_process": "GO:0007015 actin filament organization;GO:0015031 protein transport;GO:0030036 actin cytoskeleton organization;GO:0045010 actin nucleation;GO:0048477 oogenesis", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "Q24120-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q02870-1", "uniprot_id": "ERCC3_DROME", "mass": 90348.0, "length": 798, "protein_name": "General transcription and DNA repair factor IIH helicase/translocase subunit XPB", "gene_name": "hay", "organism": "Fruit fly", "refseq_name": "haywire, isoform B", "refseq_ac": "NP_001137931", "gene_names_uniprotkb": "hay; CG8019; DhR25; DhXPB; DmXPB; Dmel\\CG8019; Dmel_CG8019; ERCC3; Hay; TFIIH; XPB; Xpb; hay; hwr; i50; ms(3)nc2; nc2", "gene_names_refseq": "CG8019; DhR25; DhXPB; DmXPB; Dmel\\CG8019; ERCC3; Hay; TFIIH; XPB; Xpb/hay; Xpb; hay; hwr; i50; ms(3)nc2; nc2", "protein_names_uniprotkb": "General transcription and DNA repair factor IIH helicase/translocase subunit XPB; 5.6.2.4; ATP-dependent DNA helicase hay; DNA 3'-5' helicase/translocase XPB; DNA excision repair protein haywire; ERCC-3 homolog protein; ERCC3Dm; TFIIH subunit XPB", "protein_names_refseq": "CG8019-PB; hay-PB; haywire, isoform B; haywire", "tax_id": 7227, "disease": "xeroderma pigmentosum (Disease Ontology:DOID:0050427); xeroderma pigmentosum group B (Disease Ontology:DOID:0110850); trichothiodystrophy (Disease Ontology:DOID:0111866); photosensitive trichothiodystrophy 2 (Disease Ontology:DOID:0111869); Alzheimer's disease (Disease Ontology:DOID:10652); asphyxia neonatorum (Disease Ontology:DOID:11088); Down syndrome (Disease Ontology:DOID:14250); Cockayne syndrome (Disease Ontology:DOID:2962); lung non-small cell carcinoma (Disease Ontology:DOID:3908); colorectal cancer (Disease Ontology:DOID:9256)", "pathway": " (dme:Dmel_CG8019); (R-DME-112382); (R-DME-113418); (R-DME-5696395); (R-DME-5696400); (R-DME-674695); (R-DME-6781823); (R-DME-6782135); (R-DME-6782210); (R-DME-6796648); (R-DME-72086); (R-DME-73772); (R-DME-73776); (R-DME-73779); (R-DME-75953); (R-DME-75955); (R-DME-76042); (R-DME-77075)", "pathway_count": 18, "publication_count": 14, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;1454518;1458540;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "ATP-dependent 3'-5' DNA helicase/translocase; binds dsDNA rather than ssDNA, unzipping it in a translocase rather than classical helicase activity. Component of the general transcription and DNA repair factor IIH (TFIIH) core complex. When complexed to CDK-activating kinase (CAK), involved in RNA transcription by RNA polymerase II. The ATPase activity of XPB/ERCC3, but not its helicase activity, is required for DNA opening; it may wrap around the damaged DNA wedging it open, causing localized melting and twisting that allows XPD/ERCC2 helicase to anchor. The ATP-dependent helicase activity of XPB/ERCC3 may be required for promoter escape. Also involved in transcription-coupled nucleotide excision repair (NER) of damaged DNA. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. The structure of the TFIIH transcription complex differs from the NER-TFIIH complex; large movements by XPD/ERCC2 and XPB/ERCC3 are stabilized by XPA., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 10, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q1LZ27;Q2PJB4;Q960M8;Q9VTA2", "ec_number_list": "3.6.4.13;7.2.2.-;3.6.4.-;2.7.11.22;2.7.11.23;2.7.7.6;3.6.4.10;2.4.2.-;2.4.2.30;3.6.4.6;3.6.4.12;2.7.11.1;5.6.2.4;3.1.-.-;5.6.2.5;2.7.4.3;5.6.2.3;3.6.1.15;5.2.1.8;2.7.7.7;3.1.11.-;6.5.1.1;2.1.1.56;3.-.-.-;5.6.1.1;3.4.19.12;3.1.3.16;3.6.-.-;5.6.2.-;3.4.-.-", "go_molecular_function": "GO:0043138 3'-5' DNA helicase activity;GO:0003677 DNA binding;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0004386 helicase activity", "go_cellular_component": "GO:0097550 transcription preinitiation complex;GO:0005634 nucleus;GO:0005675 transcription factor TFIIH holo complex;GO:0000112 nucleotide-excision repair factor 3 complex", "go_biological_process": "GO:0009411 response to UV;GO:0006366 transcription by RNA polymerase II;GO:0006367 transcription initiation at RNA polymerase II promoter;GO:0006289 nucleotide-excision repair;GO:0001111 RNA polymerase II promoter clearance", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "Q02870-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P83099-1", "uniprot_id": "KPC4_DROME", "mass": 76333.0, "length": 671, "protein_name": "Putative protein kinase C delta type homolog", "gene_name": "Pkcdelta", "organism": "Fruit fly", "refseq_name": "protein kinase C delta, isoform D", "refseq_ac": "NP_001138191", "gene_names_uniprotkb": "Pkcdelta; CG10524; CG11245; CG42349; Dmel\\CG42349; Dmel_CG42349; PKCdelta; PKCd; delta PKC; mfd", "gene_names_refseq": "CG10524; CG11245; CG42349; Dmel\\CG42349; PKCdelta; PKCd; Pkcdelta; delta PKC; mfd", "protein_names_uniprotkb": "Putative protein kinase C delta type homolog; 2.7.11.13", "protein_names_refseq": "CG42349-PD; Pkcdelta-PD; myofibrillar defect; protein kinase C delta, isoform D; protein kinase C delta", "tax_id": 7227, "disease": "stroke (Disease Ontology:DOID:0051061); muscular disease (Disease Ontology:DOID:0080000); autoimmune lymphoproliferative syndrome type 3 (Disease Ontology:DOID:0110119); portal hypertension (Disease Ontology:DOID:10762); hypertension (Disease Ontology:DOID:10763); hyperinsulinism (Disease Ontology:DOID:2018); brain ischemia (Disease Ontology:DOID:2316); prostate adenocarcinoma (Disease Ontology:DOID:2526); restrictive cardiomyopathy (Disease Ontology:DOID:397); retinal detachment (Disease Ontology:DOID:5327); steatotic liver disease (Disease Ontology:DOID:9452); obesity (Disease Ontology:DOID:9970)", "pathway": " (dme:Dmel_CG42349); (R-DME-111465); (R-DME-111933); (R-DME-114508); (R-DME-1250196); (R-DME-1489509); (R-DME-202424); (R-DME-2029485); (R-DME-2871837); (R-DME-373752); (R-DME-450520); (R-DME-5218921); (R-DME-5607764); (R-DME-6798695); (R-DME-9648002)", "pathway_count": 15, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 12, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q5BIE9;Q9VYN2", "ec_number_list": "2.7.11.17;2.7.11.1;2.7.11.13;2.7.11.24;3.5.2.17;3.2.1.17;3.2.1.31;2.7.11.22;3.4.22.-;3.5.3.1;2.7.11.21;3.6.5.2;5.6.1.8;2.7.11.11;2.7.11.23;2.7.11.-;2.7.11.16;2.7.12.1;2.7.11.25;2.7.11.12;1.1.1.205;2.7.12.2;3.6.4.6;1.16.3.1;3.2.1.-;3.4.19.9;3.5.1.26;2.7.10.2;5.3.99.3;3.2.1.23;6.3.4.21;4.6.1.19;3.2.1.51;3.5.4.4;2.7.11.39;2.7.1.91;1.11.2.-;2.4.1.1;1.6.2.2", "go_molecular_function": "GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0008270 zinc ion binding;GO:0004687 myosin light chain kinase activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0035556 intracellular signal transduction;GO:0060361 flight", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "P83099-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P28286-1", "uniprot_id": "5HT2B_DROME", "mass": 67530.0, "length": 617, "protein_name": "5-hydroxytryptamine receptor 2B", "gene_name": "5-HT1B", "organism": "Fruit fly", "refseq_name": "5-hydroxytryptamine (serotonin) receptor 1B, isoform E", "refseq_ac": "NP_001137708", "gene_names_uniprotkb": "5-HT1B; 5-HT-dro2B; 5-HT1BDro; 5-HT1b; 5-HT[1B]Dro; 5-HT[[1BDro]]; 5-HT[[1B]]DRO; 5-HT[[1B]]Dro; 5-HT[[1B]]; 5-HT[[dro2B]]; 5-HT; 5HT-1B; 5HT-R2B; 5HT-dro2B; 5HT-dro[[2B]]; 5HT1B-R; 5HT1B; 5HT1b; 5HTR1B; 5htdro2b; CG15113; CG30126; DRO2B; Dm5-HT1B; Dm5-HT[[1B]]; Dm5HTdro2B; Dmel\\CG15113; Dmel_CG15113; HT1B; d5-HT1B", "gene_names_refseq": "5-HT-dro2B; 5-HT1BDro; 5-HT1B; 5-HT1b; 5-HT[1B]Dro; 5-HT[[1BDro]]; 5-HT[[1B]]DRO; 5-HT[[1B]]Dro; 5-HT[[1B]]; 5-HT[[dro2B]]; 5-HT; 5HT-1B; 5HT-R2B; 5HT-dro2B; 5HT-dro[[2B]]; 5HT1B-R; 5HT1B; 5HT1b; 5HTR1B; 5htdro2b; CG15113; CG30126; DRO2B; Dm5-HT1B; Dm5-HT[[1B]]; Dm5HTdro2B; Dmel\\CG15113; HT1B; d5-HT1B", "protein_names_uniprotkb": "5-hydroxytryptamine receptor 2B; 5-HT receptor 1B; 5-HT receptor 2B; 5-hydroxytryptamine receptor 1B; Serotonin receptor 1B; Serotonin receptor 2B", "protein_names_refseq": "5-HT1B-PE; 5-hydroxytryptamine (serotonin) receptor 1B, isoform E; CG15113-PE; drosophila serotonin receptor 1B; serotonin receptor 1B; serotonin receptor 2B", "tax_id": 7227, "disease": "alcohol dependence (Disease Ontology:DOID:0050741); nicotine dependence (Disease Ontology:DOID:0050742); withdrawal disorder (Disease Ontology:DOID:0060001); Alzheimer's disease (Disease Ontology:DOID:10652); antisocial personality disorder (Disease Ontology:DOID:10939); attention deficit hyperactivity disorder (Disease Ontology:DOID:1094); conduct disorder (Disease Ontology:DOID:12995); generalized anxiety disorder (Disease Ontology:DOID:14320); Parkinson's disease (Disease Ontology:DOID:14330); major depressive disorder (Disease Ontology:DOID:1470); alcohol use disorder (Disease Ontology:DOID:1574); depressive disorder (Disease Ontology:DOID:1596); anxiety disorder (Disease Ontology:DOID:2030); substance abuse (Disease Ontology:DOID:302); panic disorder (Disease Ontology:DOID:594); cocaine abuse (Disease Ontology:DOID:809); subacute delirium (Disease Ontology:DOID:8645)", "pathway": " (dme:Dmel_CG15113); (R-DME-390666)", "pathway_count": 2, "publication_count": 13, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;1310937;15611167;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins which inhibit adenylate cyclase., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 4, "predicted_n_glycosites": 4, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 17, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "A8E6N2;B7YZK9;C0PV72;Q059D0;Q5MRS0;Q5MRY0;Q5MS20;Q5MS32;Q5MS65;Q5MS79;Q5MS95;Q5MSA8;Q5MSB9;Q5MSC3;Q5MSC5;Q5MSC6;Q5MSD0;Q5MSD8;Q5MSE2;Q5MSF4;Q5MSG4;Q5MSH7;Q5MSV8;Q5MSW1;Q5MSW3;Q5MSX1;Q5MSX4;Q5MSX6;Q5MSX8;Q5MSY0;Q5MSY1;Q5MSY6;Q5MSY7;Q5MSZ2;Q5MSZ3;Q5MSZ4;Q5MSZ6;Q5MSZ7;Q5MT00;Q5MT01;Q5MT02;Q5MT07;Q5MT08;Q5MT10;Q5MT11;Q5MT12;Q5MT24;Q5MT25;Q5MT26;Q5MT27;Q5MT32;Q5MT34;Q5MT37;Q5MT38;Q5MT48;Q5MT57;Q5MT58;Q5MT65;Q5MT69;Q5MT71;Q5MT78;Q5MTA0;Q5MTC0;Q5MTC7;Q5MTD4;Q5MTE0;Q5MTE1;Q5MTE2;Q5MTE5;Q5MTE8;Q9V8Q3", "ec_number_list": "", "go_molecular_function": "GO:0004993 G protein-coupled serotonin receptor activity;GO:0030594 neurotransmitter receptor activity;GO:0008227 G protein-coupled amine receptor activity;GO:0001586 Gi/o-coupled serotonin receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane;GO:0030425 dendrite;GO:0045202 synapse", "go_biological_process": "GO:0007187 G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007268 chemical synaptic transmission;GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway;GO:0007210 serotonin receptor signaling pathway;GO:0007208 phospholipase C-activating serotonin receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "P28286-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P28750-1", "uniprot_id": "EXU_DROME", "mass": 57975.0, "length": 532, "protein_name": "Maternal protein exuperantia", "gene_name": "exu", "organism": "Fruit fly", "refseq_name": "exuperantia, isoform D", "refseq_ac": "NP_001163218", "gene_names_uniprotkb": "exu; CG8994; Dmel\\CG8994; Dmel_CG8994; Exu; bs30h09.y1; exu1", "gene_names_refseq": "CG8994; Dmel\\CG8994; Exu; bs30h09.y1; exu1; exu", "protein_names_uniprotkb": "Maternal protein exuperantia", "protein_names_refseq": "CG8994-PD; exu-PD; exuperantia, isoform D; exuperantia; exuperentia", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG8994)", "pathway_count": 1, "publication_count": 17, "publication_id_list": "10662770;10731132;11546740;12537568;12537569;12537572;12537573;12537574;16110336;1752438;1756733;17569856;17569867;18327897;25589440;26109356;26109357", "class_list": "", "function": "Ensures the proper localization of the mRNA of the bicoid gene to the anterior regions of the oocyte thus playing a fundamental role in the establishment of the polarity of the oocyte. May bind the bcd mRNA., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A4UZR1;Q9V967", "ec_number_list": "", "go_molecular_function": "GO:0042803 protein homodimerization activity;GO:0003727 single-stranded RNA binding;GO:0003723 RNA binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0000932 P-body;GO:0036464 cytoplasmic ribonucleoprotein granule;GO:0071011 precatalytic spliceosome", "go_biological_process": "GO:0007283 spermatogenesis;GO:0000398 mRNA splicing, via spliceosome;GO:0008595 anterior/posterior axis specification, embryo;GO:0007300 ovarian nurse cell to oocyte transport;GO:0045450 bicoid mRNA localization", "synthesized_glycan_count": 0, "hit_score": 1.8, "record_id": "P28750-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P32865-1", "uniprot_id": "GPRK1_DROME", "mass": 80566.0, "length": 700, "protein_name": "G protein-coupled receptor kinase 1", "gene_name": "Gprk1", "organism": "Fruit fly", "refseq_name": "G protein-coupled receptor kinase 1, isoform A", "refseq_ac": "NP_001036438", "gene_names_uniprotkb": "Gprk1; CG40129; CT4320; Dmel\\CG40129; Dmel_CG40129; GPRK1; Gprk-1; RK; Rok; gprk1", "gene_names_refseq": "CG40129; CT4320; Dmel\\CG40129; GPRK1; Gprk-1; Gprk1; RK; Rok; gprk1", "protein_names_uniprotkb": "G protein-coupled receptor kinase 1; 2.7.11.16", "protein_names_refseq": "CG40129-PA; G protein-coupled receptor kinase 1, isoform A; Gprk1-PA; rhodopsin kinase", "tax_id": 7227, "disease": "limb ischemia (Disease Ontology:DOID:0050852); portal hypertension (Disease Ontology:DOID:10762); hypertension (Disease Ontology:DOID:10763); toxic shock syndrome (Disease Ontology:DOID:14115); Parkinson's disease (Disease Ontology:DOID:14330); hypothyroidism (Disease Ontology:DOID:1459); impotence (Disease Ontology:DOID:1875); opiate dependence (Disease Ontology:DOID:2559); bipolar disorder (Disease Ontology:DOID:3312); pituitary adenoma (Disease Ontology:DOID:3829); hyperglycemia (Disease Ontology:DOID:4195); liver cirrhosis (Disease Ontology:DOID:5082); congestive heart failure (Disease Ontology:DOID:6000); rheumatoid arthritis (Disease Ontology:DOID:7148); bacterial pneumonia (Disease Ontology:DOID:874)", "pathway": " (dme:Dmel_CG40129); (R-DME-111933); (R-DME-416476); (R-DME-418555); (R-DME-5635838)", "pathway_count": 5, "publication_count": 12, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;1662381;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "Specifically phosphorylates the activated forms of G protein-coupled receptors., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 15, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "B5RJK1;Q4V555;Q7PLS9", "ec_number_list": "2.7.11.13;2.7.11.-;2.7.11.16;2.7.11.1", "go_molecular_function": "GO:0005524 ATP binding;GO:0001664 G protein-coupled receptor binding;GO:0004703 G protein-coupled receptor kinase activity;GO:0035091 phosphatidylinositol binding;GO:0050254 rhodopsin kinase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane", "go_biological_process": "GO:0045880 positive regulation of smoothened signaling pathway;GO:0007186 G protein-coupled receptor signaling pathway;GO:0007603 phototransduction, visible light;GO:0009966 regulation of signal transduction;GO:0016060 negative regulation of phospholipase C-activating phototransduction signaling pathway", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "P32865-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P29673-1", "uniprot_id": "APTE_DROME", "mass": 52053.0, "length": 469, "protein_name": "Protein apterous", "gene_name": "ap", "organism": "Fruit fly", "refseq_name": "apterous, isoform C", "refseq_ac": "NP_001163058", "gene_names_uniprotkb": "ap; AP; Apt; Ap; CG8376; Dmel\\CG8376; Dmel_CG8376; LIM; S-2a; Xa; blt; neuro; trw", "gene_names_refseq": "AP; Apt; Ap; CG8376; Dmel\\CG8376; LIM; S-2a; Xa; ap; blt; neuro; trw", "protein_names_uniprotkb": "Protein apterous", "protein_names_refseq": "APTEROUS; CG8376-PC; ap-PC; apterous, isoform C; apteroys; neuromuscular; no-wings; tornwing; xasta", "tax_id": 7227, "disease": "depressive disorder (Disease Ontology:DOID:1596)", "pathway": " (dme:Dmel_CG8376)", "pathway_count": 1, "publication_count": 22, "publication_id_list": "10488341;10488342;10731132;10751171;12537568;12537569;12537572;12537573;12537574;1349545;1524829;16110336;17569856;17569867;20040493;25589440;26109356;26109357;9334334;9744867;9806924;9843490", "class_list": "", "function": "Transcription factor that regulates expression of genes by directly binding to enhancer elements (PubMed:9806924). Cooperates with Chi/Chip and Bx/Beadex during wing imaginal discs dorso-ventral compartmentalization and wing margin formation; Chi activates transcription factor activity by mediating dimerization while Bx interferes with this interaction (PubMed:10488342, PubMed:9843490). Regulates expression of Bx in wing imaginal discs in an autoregulatory negative feedback loop (PubMed:9744867). Involved in expression of FMRFamide-related peptides in neuroendocrine Tv neurons (PubMed:9806924). Required for the normal development of the wing and halter imaginal disks (PubMed:10488341)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q8T9D4;Q9V9H5", "ec_number_list": "", "go_molecular_function": "GO:0046872 metal ion binding;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677 DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0007399 nervous system development;GO:0010628 positive regulation of gene expression;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0007517 muscle organ development", "synthesized_glycan_count": 0, "hit_score": 2.3, "record_id": "P29673-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9NFZ3-1", "uniprot_id": "GBGE_DROME", "mass": 8398.0, "length": 72, "protein_name": "Guanine nucleotide-binding protein subunit gamma-e", "gene_name": "Ggamma30A", "organism": "Fruit fly", "refseq_name": "G protein gamma subunit 30A, isoform H", "refseq_ac": "NP_001162918", "gene_names_uniprotkb": "Ggamma30A; CG18511; CG3694; CG43733; Dmel\\CG3694; Dmel_CG3694; G-gamma30A; GNG gene like; G[[gamma30A]]; G[[gamma]]; Galpha30A; Ggamma[[e]]; Ggammae; Ggamma; lincRNA.S701", "gene_names_refseq": "CG18511; CG3694; CG43733; Dmel\\CG3694; G-gamma30A; GNG gene like; G[[gamma30A]]; G[[gamma]]; Galpha30A; Ggamma30A; Ggamma[[e]]; Ggammae; Ggamma; lincRNA.S701", "protein_names_uniprotkb": "Guanine nucleotide-binding protein subunit gamma-e; Ggamma(e)", "protein_names_refseq": "CG3694-PH; G protein gamma subunit 30A, isoform H; G protein gamma30A; G protein subunit gamma at 30A; Ggamma30A-PH", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG3694); (R-DME-1296041); (R-DME-418594); (R-DME-418597); (R-DME-428930); (R-DME-8964616); (R-DME-997272)", "pathway_count": 7, "publication_count": 14, "publication_id_list": "10608815;10731132;12537568;12537569;12537572;12537573;12537574;15205461;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A4V0H1;Q95RZ3;Q9VLD3", "ec_number_list": "", "go_molecular_function": "GO:0031681 G-protein beta-subunit binding;GO:0046982 protein heterodimerization activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0030424 axon;GO:0005834 heterotrimeric G-protein complex;GO:0016028 rhabdomere", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway;GO:0007601 visual perception;GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway;GO:0007602 phototransduction;GO:0050909 sensory perception of taste", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "Q9NFZ3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P92208-1", "uniprot_id": "JNK_DROME", "mass": 43027.0, "length": 372, "protein_name": "Stress-activated protein kinase JNK", "gene_name": "bsk", "organism": "Fruit fly", "refseq_name": "basket, isoform F", "refseq_ac": "NP_001162930", "gene_names_uniprotkb": "bsk; BSK; Basket; Bsk; CG5680; D-JNK; D-junk; DJNK; DmJNK; Dmel\\CG5680; Dmel_CG5680; JAK; JNK; Jak; Jnk; Junk; P-JNK; SAPKa; SAPK; bsk; dJNK; dJnk; dNJNK; jnk (bsk); jnk; p-JNK; pJNK", "gene_names_refseq": "BSK; Basket; Bsk; CG5680; D-JNK; D-junk; DBSK/JNK; DJNK/bsk; DJNK; DmJNK; Dmel\\CG5680; JAK; JNK/SAPK; JNK; Jak; Jnk; Junk; P-JNK; SAPK/JNK; SAPKa; bsk/JNK; bsk; dJNK; dJnk; dNJNK; jnk (bsk); jnk; p-JNK; pJNK", "protein_names_uniprotkb": "Stress-activated protein kinase JNK; 2.7.11.24; Protein basket; dJNK", "protein_names_refseq": "CG5680-PF; JNK; JUN kinase; Jun N-terminal kinase; Jun NH2-terminal kinase; Jun-N terminal kinase; Jun-kinase; basket, isoform F; basket; bsk-PF; c-Jun N-terminal kinase; c-Jun aminoterminal kinase; c-Jun-N-terminal kinase; pJNK", "tax_id": 7227, "disease": "colorectal adenoma (Disease Ontology:DOID:0050860); colorectal adenocarcinoma (Disease Ontology:DOID:0050861); stroke (Disease Ontology:DOID:0051061); pre-malignant neoplasm (Disease Ontology:DOID:0060071); metabolic dysfunction-associated steatotic liver disease (Disease Ontology:DOID:0080208); Parkinsonism (Disease Ontology:DOID:0080855); Alzheimer's disease (Disease Ontology:DOID:10652); hypertension (Disease Ontology:DOID:10763); Parkinson's disease (Disease Ontology:DOID:14330); alcohol use disorder (Disease Ontology:DOID:1574); rectal benign neoplasm (Disease Ontology:DOID:1984); chronic mucocutaneous candidiasis (Disease Ontology:DOID:2058); brain ischemia (Disease Ontology:DOID:2316); chronic obstructive pulmonary disease (Disease Ontology:DOID:3083); pancreatic adenocarcinoma (Disease Ontology:DOID:4074); anti-basement membrane glomerulonephritis (Disease Ontology:DOID:4780); myocardial infarction (Disease Ontology:DOID:5844); hepatocellular carcinoma (Disease Ontology:DOID:684); abdominal aortic aneurysm (Disease Ontology:DOID:7693); colorectal cancer (Disease Ontology:DOID:9256); type 2 diabetes mellitus (Disease Ontology:DOID:9352)", "pathway": " (dme:Dmel_CG5680); (R-DME-193648); (R-DME-209397); (R-DME-209409); (R-DME-209425); (R-DME-209459); (R-DME-2559580); (R-DME-2871796); (R-DME-450321); (R-DME-450341); (R-DME-9007892)", "pathway_count": 11, "publication_count": 35, "publication_id_list": "10028968;10433922;10572048;10731132;10903185;11784101;11865058;12537568;12537569;12537572;12537573;12537574;16110336;17192257;1749429;17569856;17569867;18456458;1922387;20035736;22227521;25589440;25594180;25836674;26109356;26109357;28396149;31704968;37138087;7816143;8137421;8946915;8946916;9224720;9472024", "class_list": "", "function": "Mitogen-activated protein kinase and key component of the c-Jun N-terminal kinase (JNK) pathway which phosphorylate and activate transcription factors involved in a wide range of biological processes including response to various stresses, cellular proliferation, differentiation and migration, and regulation of cell shape (PubMed:10433922, PubMed:11784101, PubMed:22227521, PubMed:25594180, PubMed:28396149, PubMed:37138087, PubMed:8946915, PubMed:9224720). Responds to activation by environmental stress by phosphorylating a number of transcription factors, primarily components of AP-1 such as Jra and also the transcriptional repressor aop, and thus regulates transcriptional activity (PubMed:9224720). Component of the immune response activated by bacterial infection, and is involved in wound healing and in dorsal closure, a morphogenetic movement during embryogenesis (PubMed:10433922, PubMed:11784101, PubMed:8946915, PubMed:9224720). Functions in the systematic response to wounding acting downstream of the Hayan-phenoloxidase PPO1 cascade (PubMed:22227521). During epidermal wound healing involved in cellular polarization by inducing the translocation of sktl and mys/integrin beta to the trailing edge (PubMed:31704968). Exhibits cytoprotective activity in neuronal cells in response to wounding to the integument (PubMed:22227521). Controls the expression of a phosphatase, puckered, at the edges of wounded epidermal tissue and in the dorsal epithelium during dorsal closure (PubMed:10433922, PubMed:11784101). Regulates the activity of SREBP in neurons and thereby the accumulation of lipids in glia (PubMed:25594180). Plays a role in positively regulating the expression of DIP2 independently of AP-1, thereby ensuring proper axon guidance in mushroom bodies (PubMed:28396149). In enterocytes and differentiating progenitors of the gut that are experiencing inorganic phosphate (Pi) deficiency, activated by Cka to induce nearby progenitor cells to proliferate and form new absorptive cells, probably helping the organism to cope with the nutrient deficiency by maximizing absorption of dietary Pi (PubMed:37138087)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]; Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, and thus regulates transcriptional activity., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 21, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "O01366;Q94542", "ec_number_list": "2.7.11.17;2.7.11.1;2.7.11.13;2.7.11.24;2.7.11.22;2.7.12.2;2.7.11.21;5.6.1.8;2.7.11.11;2.7.11.23;3.6.5.2;2.7.12.1;2.7.11.25;2.7.11.12;2.7.10.2;2.7.11.39", "go_molecular_function": "GO:0004672 protein kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0004705 JUN kinase activity;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0030424 axon", "go_biological_process": "GO:1903689 regulation of wound healing, spreading of epidermal cells;GO:0006979 response to oxidative stress;GO:0008284 positive regulation of cell population proliferation;GO:0010628 positive regulation of gene expression;GO:0019731 antibacterial humoral response", "synthesized_glycan_count": 0, "hit_score": 3.6, "record_id": "P92208-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P98149-1", "uniprot_id": "DIF_DROME", "mass": 73935.0, "length": 667, "protein_name": "Dorsal-related immunity factor Dif", "gene_name": "Dif", "organism": "Fruit fly", "refseq_name": "Dorsal-related immunity factor, isoform D", "refseq_ac": "NP_001162999", "gene_names_uniprotkb": "Dif; 6794; CG6794; DIF; Dif2; Dmel\\CG6794; Dmel_CG6794; NF-KB; NF-kappaB; NFkappaB; dif", "gene_names_refseq": "6794; CG6794; DIF; Dif2; Dif; Dmel\\CG6794; NF-KB; NF-kappaB; NFkappaB; dif", "protein_names_uniprotkb": "Dorsal-related immunity factor Dif", "protein_names_refseq": "CG6794-PD; Dif-PD; Dorsal-like immunity factor; Dorsal-related immunity factor, isoform D; Dorsal-related transcription factor; dorsal related immunity factor; dorsal-related immunity factor", "tax_id": 7227, "disease": "alcohol dependence (Disease Ontology:DOID:0050741); obstructive sleep apnea (Disease Ontology:DOID:0050848); oral squamous cell carcinoma (Disease Ontology:DOID:0050866); lymphoma (Disease Ontology:DOID:0060058); ductal carcinoma in situ (Disease Ontology:DOID:0060074); colitis (Disease Ontology:DOID:0060180); mastoiditis (Disease Ontology:DOID:0060322); immunodeficiency 92 (Disease Ontology:DOID:0061062); metabolic dysfunction and alcohol associated liver disease (Disease Ontology:DOID:0070508); Parkinsonism (Disease Ontology:DOID:0080855); acute necrotizing pancreatitis (Disease Ontology:DOID:0080998); immunodeficiency 53 (Disease Ontology:DOID:0111992); bacterial infectious disease (Disease Ontology:DOID:104); otitis media (Disease Ontology:DOID:10754); hypertension (Disease Ontology:DOID:10763); cholesteatoma of middle ear (Disease Ontology:DOID:10964); urinary bladder cancer (Disease Ontology:DOID:11054); prostatic hypertrophy (Disease Ontology:DOID:11132); prediabetes syndrome (Disease Ontology:DOID:11716); primary biliary cholangitis (Disease Ontology:DOID:12236); uveitis (Disease Ontology:DOID:13141); renovascular hypertension (Disease Ontology:DOID:1591); breast cancer (Disease Ontology:DOID:1612); pancreatic cancer (Disease Ontology:DOID:1793); status epilepticus (Disease Ontology:DOID:1824); epilepsy (Disease Ontology:DOID:1826); arteriosclerosis (Disease Ontology:DOID:2349); prostate adenocarcinoma (Disease Ontology:DOID:2526); transitional cell carcinoma (Disease Ontology:DOID:2671); laryngeal squamous cell carcinoma (Disease Ontology:DOID:2876); atopic dermatitis (Disease Ontology:DOID:3310); lung non-small cell carcinoma (Disease Ontology:DOID:3908); renal cell carcinoma (Disease Ontology:DOID:4450); liver cirrhosis (Disease Ontology:DOID:5082); ureteral obstruction (Disease Ontology:DOID:5199); kidney disease (Disease Ontology:DOID:557); pulmonary hypertension (Disease Ontology:DOID:6432); muscular atrophy (Disease Ontology:DOID:767); end stage renal disease (Disease Ontology:DOID:783); prostate carcinoma in situ (Disease Ontology:DOID:8634); cervix uteri carcinoma in situ (Disease Ontology:DOID:8991); steatotic liver disease (Disease Ontology:DOID:9452); encephalitis (Disease Ontology:DOID:9588); obesity (Disease Ontology:DOID:9970)", "pathway": " (dme:Dmel_CG6794); (R-DME-1169091); (R-DME-1810476); (R-DME-202424); (R-DME-209400); (R-DME-209406); (R-DME-209560); (R-DME-214842); (R-DME-214844); (R-DME-214869); (R-DME-2871837); (R-DME-3134963); (R-DME-445989); (R-DME-4755510); (R-DME-5607764); (R-DME-5621575); (R-DME-9020702); (R-DME-933542); (R-DME-9860927); (R-DME-9958825)", "pathway_count": 20, "publication_count": 35, "publication_id_list": "10072384;10197979;10369678;10660298;10731132;10843389;11532919;12456640;12537568;12537569;12537572;12537573;12537574;12973300;16110336;17032737;17569856;17569867;18000549;21576362;25477468;25589440;26109356;26109357;7705656;7859742;8242747;8808632;8948598;9025065;9367441;9405646;9405661;9553105;9990853", "class_list": "", "function": "Mediates an immune response in larvae (PubMed:8242747). DIF binds to the kappa-B consensus sequence 5'-GGRNNYYCC-3', located in the enhancer region of the immunity gene CECA1 (PubMed:8242747). Involved in the melanization immune response to bacterial challenge, possibly by acting in a Toll signaling pathway that down-regulates Spn27A in response to infection (PubMed:12456640). Part of a signaling pathway involving NF-kappa-B (rel) and Toll-related receptors, that functions in the apoptosis of unfit cells during cell competition (PubMed:25477468). May be part of a NF-kappa-B and Tollo signaling cascade that regulates development of the peripheral nervous system (PubMed:18000549)., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 44, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q1LYZ5;Q8MT54;Q9VJE2", "ec_number_list": "", "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006954 inflammatory response;GO:0006955 immune response;GO:0010628 positive regulation of gene expression;GO:0045087 innate immune response", "synthesized_glycan_count": 0, "hit_score": 3.6, "record_id": "P98149-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P15007-1", "uniprot_id": "ENO_DROME", "mass": 54310.0, "length": 500, "protein_name": "Enolase", "gene_name": "Eno", "organism": "Fruit fly", "refseq_name": "enolase, isoform F", "refseq_ac": "NP_001162853", "gene_names_uniprotkb": "Eno; BEST:LD15491; CG17654; CT32526; DmENO; Dmel\\CG17654; Dmel_CG17654; ENOA; Eno2; T18; anon-WO0153538.76; eno", "gene_names_refseq": "BEST:LD15491; CG17654; CT32526; DmENO; Dmel\\CG17654; ENOA; Eno2; Eno; T18; anon-WO0153538.76; eno", "protein_names_uniprotkb": "Enolase; 2-phospho-D-glycerate hydro-lyase; 2-phosphoglycerate dehydratase; 4.2.1.11", "protein_names_refseq": "CG17654-PF; Eno-PF; enolase, isoform F; enolase; phosphopyruvate hydratase", "tax_id": 7227, "disease": "Parkinsonism (Disease Ontology:DOID:0080855); prostate cancer (Disease Ontology:DOID:10283); Alzheimer's disease (Disease Ontology:DOID:10652); hypertension (Disease Ontology:DOID:10763); urinary bladder cancer (Disease Ontology:DOID:11054); migraine without aura (Disease Ontology:DOID:12783); toxic shock syndrome (Disease Ontology:DOID:14115); aortic valve stenosis (Disease Ontology:DOID:1712); neuroendocrine carcinoma (Disease Ontology:DOID:1800); breast carcinoma (Disease Ontology:DOID:3459); brain disease (Disease Ontology:DOID:936)", "pathway": " (dme:Dmel_CG17654); (R-DME-70171); (R-DME-70263)", "pathway_count": 3, "publication_count": 16, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17379620;17569856;17569867;2106662;25589440;26109356;26109357;26235423;8500545", "class_list": "", "function": "Enzyme of the glycolytic pathway (Probable). Glycolysis is essential in glial cells but not in neurons; neurons rely on the citric acid cycle for their energy needs, and on lactate and alanine secreted into the hemolymph by glial cells to fuel it (PubMed:26235423)., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 11, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A4UZY9;A5XD39;A5XD43;B9EQS7;C0PV73;Q8IPX8;Q8MT10;Q9VQ38", "ec_number_list": "4.2.1.11", "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0004634 phosphopyruvate hydratase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0000015 phosphopyruvate hydratase complex", "go_biological_process": "GO:0006094 gluconeogenesis;GO:0042593 glucose homeostasis;GO:0006096 glycolytic process;GO:0061621 canonical glycolysis", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "P15007-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q24248-1", "uniprot_id": "ARA_DROME", "mass": 75422.0, "length": 717, "protein_name": "Homeobox protein araucan", "gene_name": "ara", "organism": "Fruit fly", "refseq_name": "araucan, isoform A", "refseq_ac": "NP_524045", "gene_names_uniprotkb": "ara; Ara; CG10571; Dmel\\CG10571; Dmel_CG10571; IRO-C; Iro-C; IroC; Iro; iro-C; iro", "gene_names_refseq": "Ara; CG10571; Dmel\\CG10571; IRO-C; Iro-C; IroC; Iro; ara; iro-C; iro", "protein_names_uniprotkb": "Homeobox protein araucan", "protein_names_refseq": "CG10571-PA; ara-PA; aracucan; araucan, isoform A; araucan; auracan; iroquis complex; iroquois gene complex; iroquois-complex", "tax_id": 7227, "disease": "congestive heart failure (Disease Ontology:DOID:6000)", "pathway": " (dme:Dmel_CG10571)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;18327897;25589440;26109356;26109357;8620542", "class_list": "", "function": "Controls proneural and vein forming genes. Positive transcriptional controller of AC-SC (achaete-scute). May act as an activator that interacts with the transcriptional complex assembled on the AC and SC promoters and participates in transcription initiation., [UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "Q9VTZ9", "ec_number_list": "", "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677 DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0045893 positive regulation of DNA-templated transcription;GO:0030182 neuron differentiation", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "Q24248-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P29555-1", "uniprot_id": "ABDA_DROME", "mass": 62410.0, "length": 590, "protein_name": "Homeobox protein abdominal-A", "gene_name": "abd-A", "organism": "Fruit fly", "refseq_name": "abdominal A, isoform C", "refseq_ac": "NP_001163632", "gene_names_uniprotkb": "abd-A; ABD-A; Abd A; Abd-A; AbdA; Abda; BX-C; CG10325; Cbxd; DmabdA; Dmabda; Dmel\\CG10325; Dmel_CG10325; Fab-3; Fab-4; Fub; Hab; Uab; abd A; abd-a; abdA; abd_a; abda; iab-2; iab-3; iab-4; iab-5; iab2; iab3; iab4; iab; l(3)89Ec", "gene_names_refseq": "ABD-A; Abd A; Abd-A; AbdA; Abda; BX-C; CG10325; Cbxd; DmabdA; Dmabda; Dmel\\CG10325; Fab-3; Fab-4; Fub; Hab; Uab; abd A; abd-A; abd-a; abdA; abd_a; abda; iab-2; iab-3; iab-4; iab-5; iab2; iab3; iab4; iab; l(3)89Ec", "protein_names_uniprotkb": "Homeobox protein abdominal-A", "protein_names_refseq": "Abdominal-A; CG10325-PC; Front-ultraabdominal; abd-A-PC; abdominal A, isoform C; abdominal A; abdominalA; contrabithoraxoid; hyperabdominal; infra-abdominal 2; infra-abdominal 3; infra-abdominal 4; infraabdominal", "tax_id": 7227, "disease": "leukemia (Disease Ontology:DOID:1240)", "pathway": " (dme:Dmel_CG10325)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;1979297;25589440;26109356;26109357;7667301", "class_list": "", "function": "Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Required for segmental identity of the second through eighth abdominal segments. Once a pattern of abd-A expression is turned on in a given parasegment, it remains on the more posterior parasegment, so that the complex pattern of expression is built up in the successive parasegments. Appears to repress expression of Ubx whenever they appear in the same cell, but abd-A is repressed by Abd-B only in the eight and ninth abdominal segments., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q5U161;Q9VER1", "ec_number_list": "", "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0000987 cis-regulatory region sequence-specific DNA binding;GO:0043565 sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005667 transcription regulator complex;GO:0090575 RNA polymerase II transcription regulator complex;GO:0005704 polytene chromosome band", "go_biological_process": "GO:0048806 genitalia development;GO:0007501 mesodermal cell fate specification;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0007399 nervous system development;GO:0007507 heart development", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "P29555-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P27781-1", "uniprot_id": "CUP9_DROME", "mass": 15260.0, "length": 159, "protein_name": "Pupal cuticle protein Edg-91", "gene_name": "Edg91", "organism": "Fruit fly", "refseq_name": "Ecdysone-dependent gene 91, isoform A", "refseq_ac": "NP_524390", "gene_names_uniprotkb": "Edg91; CG7539; Dmel\\CG7539; Dmel_CG7539; EDG-91; EDG91", "gene_names_refseq": "CG7539; Dmel\\CG7539; EDG-91; EDG91; Edg91", "protein_names_uniprotkb": "Pupal cuticle protein Edg-91; Ecdysone-dependent protein 91", "protein_names_refseq": "CG7539-PA; Ecdysone-dependent gene 91, isoform A; Edg91-PA", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG7539)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;1713868;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "Component of the pupal cuticle., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9VEI1", "ec_number_list": "", "go_molecular_function": "GO:0008011 structural constituent of pupal chitin-based cuticle", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "P27781-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P54367-1", "uniprot_id": "KC1A_DROME", "mass": 39535.0, "length": 337, "protein_name": "Casein kinase I isoform alpha", "gene_name": "CkIalpha", "organism": "Fruit fly", "refseq_name": "casein kinase ialpha, isoform D", "refseq_ac": "NP_001162737", "gene_names_uniprotkb": "CkIalpha; CG2028; CK I; CK1alpha; CK1a; CK1; CKI alpha; CKIalpha; CKIa; CKI; Ck1alpha; Ck1a; CkI alpha; CkIa; Dmel\\CG2028; Dmel_CG2028; PKA-C; anon-WO03040301.93; anon-WO03040301.95; ck1alpha; ck1a; ckIalpha; ckI; dmCK1; dmckI; l(1)G0492", "gene_names_refseq": "CG2028; CK I; CK1alpha; CK1a; CK1; CKI alpha; CKIalpha; CKIa; CKI; Ck1alpha; Ck1a; CkI alpha; CkIalpha; CkIa; Dmel\\CG2028; PKA-C; anon-WO03040301.93; anon-WO03040301.95; ck1alpha; ck1a; ckIalpha; ckI; dmCK1; dmckI; l(1)G0492", "protein_names_uniprotkb": "Casein kinase I isoform alpha; 2.7.11.1; CKI-alpha; DmCK1", "protein_names_refseq": "CG2028-PD; CkIalpha-PD; caesin kinase I alpha; casein kinase 1alpha; casein kinase I; casein kinase ialpha, isoform D; casein kinase ialpha; casein kinase-1", "tax_id": 7227, "disease": "Alzheimer's disease (Disease Ontology:DOID:10652); inclusion body myositis (Disease Ontology:DOID:3429)", "pathway": " (dme:Dmel_CG2028); (R-DME-195253); (R-DME-196299); (R-DME-209155); (R-DME-209159); (R-DME-209190); (R-DME-209214); (R-DME-209360); (R-DME-209396); (R-DME-209413); (R-DME-209440); (R-DME-209461); (R-DME-432553); (R-DME-5610785); (R-DME-5635838); (R-DME-69601)", "pathway_count": 16, "publication_count": 85, "publication_id_list": "10073940;10102270;10196136;10409506;10421629;10457025;10458606;10477300;10557210;10731132;10825151;10838083;10846164;11090136;11336703;11430804;11440719;11912487;11914126;11927557;11955435;11955436;12000790;12122057;12231619;12432393;12442174;12447397;12537568;12537569;12537572;12537573;12537574;12563262;12636921;12663920;12781135;12944510;14636582;14636583;14731402;14759367;14966281;15063184;15300262;15459103;15563523;15592457;15598741;15616566;15691767;15875013;16041759;16110336;16299518;16319317;16326393;16386907;16410523;16630821;17077139;17418796;17569856;17569867;17925225;18593878;18815259;22095083;25589440;25723539;26109356;26109357;7481773;8596938;8600384;8832407;8898207;8906787;8906794;8938123;8990193;9215627;9482888;9601642;9674431", "class_list": "", "function": "Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. Can phosphorylate a large number of proteins. Negative regulator of wg signaling (PubMed:22095083). Phosphorylates arm directly or indirectly and stimulates its degradation which prevents inappropriate wg signaling (PubMed:11927557, PubMed:11955436, PubMed:22095083). Phosphorylates smo which promotes its accumulation at the cell surface and its signaling activity in response to hh (PubMed:15616566). Together with dco, regulates proteolytic processing of ci by phosphorylating it, which promotes its binding to slmb, the F-box recognition component of the SCF(slmb) E3 ubiquitin-protein ligase required for ci processing (PubMed:16326393). Inhibits condensin II interphase activity by promoting degradation of the Cap-H2 regulatory subunit and limiting the levels of chromatin-bound Cap-H2 which regulates interphase chromosome organization (PubMed:25723539)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A4V4D3;Q0KHT2;Q9VYK2", "ec_number_list": "2.7.11.17;2.7.11.1;2.7.11.13;2.7.11.24;2.7.11.22;2.7.11.21;5.6.1.8;2.7.11.11;3.1.3.48;2.7.11.23;3.1.3.16;2.3.2.23;2.7.11.-;2.7.11.16;2.7.12.1;2.7.11.26;2.7.11.25;2.7.11.12;2.7.12.2;2.7.10.2;3.4.19.-;5.6.1.5;3.4.19.12;2.7.11.39", "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0030877 beta-catenin destruction complex", "go_biological_process": "GO:0045880 positive regulation of smoothened signaling pathway;GO:0006281 DNA repair;GO:0007165 signal transduction;GO:0090090 negative regulation of canonical Wnt signaling pathway;GO:0042593 glucose homeostasis", "synthesized_glycan_count": 0, "hit_score": 8.6, "record_id": "P54367-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q8IR79-1", "uniprot_id": "LIMK1_DROME", "mass": 139304.0, "length": 1257, "protein_name": "LIM domain kinase 1", "gene_name": "LIMK1", "organism": "Fruit fly", "refseq_name": "LIM domain kinase 1, isoform E", "refseq_ac": "NP_001162733", "gene_names_uniprotkb": "LIMK1; CG1848; D-LIMK1; D-Limk; DLIMK1; DLIMK; Dlimk; Dmel\\CG1848; Dmel_CG1848; LIM-kinase 1; LIMK-1; LIMK; LimK1; LimK; Limk1; Limk; agn; ag; dLIMK1; dLIMK; l(1)11Af; limK1; limk1; limk; ts398", "gene_names_refseq": "CG1848; D-LIMK1; D-Limk; DLIMK1; DLIMK; Dlimk; Dmel\\CG1848; LIM-kinase 1; LIMK-1; LIMK1; LIMK; LimK1; LimK; Limk1; Limk; agn; ag; dLIMK1; dLIMK; l(1)11Af; limK1; limk1; limk; ts398", "protein_names_uniprotkb": "LIM domain kinase 1; 2.7.11.1; LIMK-1; dLIMK", "protein_names_refseq": "CG1848-PE; LIM Kinase1; LIM domain kinase 1, isoform E; LIM domain protein kinase; LIM kinase 1; LIM-DOMAIN KINASE; LIM-kinase 1; LIM-kinase1; LIMK1-PE; Lim kinase; agnostic; im kinase", "tax_id": 7227, "disease": "Williams-Beuren syndrome (Disease Ontology:DOID:1928)", "pathway": " (dme:Dmel_CG1848); (R-DME-2029482); (R-DME-399954); (R-DME-5627123)", "pathway_count": 4, "publication_count": 18, "publication_id_list": "10731132;11027607;12537568;12537569;12537572;12537573;12537574;14972681;15220930;15572110;15657426;16110336;17372656;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "Protein kinase which regulates actin filament dynamics. Phosphorylates and inactivates the actin binding/depolymerizing factor tsr/cofilin, thereby stabilizing the actin cytoskeleton. Modulation of actin cytoskeleton dynamics may be essential for imaginal disk morphogenesis and axon guidance., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q8IR78;Q9GV18;Q9GV19;Q9VYL6", "ec_number_list": "2.7.11.1;2.7.11.17;2.7.11.13;2.7.11.24;2.7.11.22;2.7.11.21;5.6.1.8;2.7.11.11;2.7.11.23;2.7.12.1;2.7.11.25;2.7.11.12;2.7.12.2;2.7.10.2;2.7.11.39", "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0032154 cleavage furrow;GO:0030496 midbody", "go_biological_process": "GO:0030036 actin cytoskeleton organization;GO:0007560 imaginal disc morphogenesis;GO:0050770 regulation of axonogenesis;GO:0048749 compound eye development;GO:0051124 synaptic assembly at neuromuscular junction", "synthesized_glycan_count": 0, "hit_score": 1.9, "record_id": "Q8IR79-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q0E940-1", "uniprot_id": "EIF3B_DROME", "mass": 80441.0, "length": 690, "protein_name": "Eukaryotic translation initiation factor 3 subunit B", "gene_name": "eIF3b", "organism": "Fruit fly", "refseq_name": "eukaryotic translation initiation factor 3 subunit b, isoform B", "refseq_ac": "NP_611228", "gene_names_uniprotkb": "eIF3b; CG4878; Dmel\\CG4878; Dmel_CG4878; EIF3B; SN2-6; cg4878; eIF3 S9; eIF3-S9; eIF3-s9; eIF3B; eIF3", "gene_names_refseq": "CG4878; Dmel\\CG4878; EIF3B; SN2-6; cg4878; eIF3 S9; eIF3-S9; eIF3-s9; eIF3B; eIF3b; eIF3", "protein_names_uniprotkb": "Eukaryotic translation initiation factor 3 subunit B; Eukaryotic translation initiation factor 3 subunit 9; eIF3b", "protein_names_refseq": "CG4878-PB; eIF3-S9; eIF3b-PB; eukaryotic translation initiation factor 3 subunit b, isoform B; suppressor of NA9 2-6", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG4878); (R-DME-156827); (R-DME-72649); (R-DME-72689); (R-DME-72695); (R-DME-72702)", "pathway_count": 6, "publication_count": 14, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17392269;17569856;17569867;23716590;25589440;26109356;26109357", "class_list": "", "function": "Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome., [UniProtKB, UniProtKB]; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation., [UniProtKB, HAMAP, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "C0PUW0;Q8MR84", "ec_number_list": "", "go_molecular_function": "GO:0003729 mRNA binding;GO:0003743 translation initiation factor activity;GO:0031369 translation initiation factor binding;GO:0003723 RNA binding", "go_cellular_component": "GO:0005829 cytosol;GO:0016282 eukaryotic 43S preinitiation complex;GO:0033290 eukaryotic 48S preinitiation complex;GO:0005852 eukaryotic translation initiation factor 3 complex", "go_biological_process": "GO:0006413 translational initiation;GO:0006446 regulation of translational initiation;GO:0001732 formation of cytoplasmic translation initiation complex;GO:0030707 follicle cell of egg chamber development", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "Q0E940-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q94529-1", "uniprot_id": "GS1_DROME", "mass": 25785.0, "length": 231, "protein_name": "Probable pseudouridine-5'-phosphatase", "gene_name": "Gs1l", "organism": "Fruit fly", "refseq_name": "GS1-like, isoform A", "refseq_ac": "NP_477228", "gene_names_uniprotkb": "Gs1l; 19864674; CG15441; Dmel\\CG15441; Dmel_CG15441; GS1l; gs1-like", "gene_names_refseq": "19864674; CG15441; Dmel\\CG15441; GS1l; Gs1l; gs1-like", "protein_names_uniprotkb": "Probable pseudouridine-5'-phosphatase; 3.1.3.96; 5'-PsiMPase; GS1-like protein; Pseudouridine-5'-monophosphatase", "protein_names_refseq": "CG15441-PA; GS1-like protein; GS1-like, isoform A; GS1like; Gs1l-PA", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG15441); (R-DME-73614)", "pathway_count": 2, "publication_count": 12, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357;9055824", "class_list": "", "function": "Dephosphorylates pseudouridine 5'-phosphate, a potential intermediate in rRNA degradation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "O02536;Q494L7;Q9VR01", "ec_number_list": "3.1.3.96", "go_molecular_function": "GO:0046872 metal ion binding;GO:0016791 phosphatase activity;GO:1990738 pseudouridine 5'-phosphatase activity", "go_cellular_component": "", "go_biological_process": "GO:0009117 nucleotide metabolic process;GO:0042060 wound healing", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "Q94529-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q960V3-1", "uniprot_id": "MILT_DROME", "mass": 120649.0, "length": 1122, "protein_name": "Trafficking kinesin-binding protein milt", "gene_name": "milt", "organism": "Fruit fly", "refseq_name": "milton, isoform E", "refseq_ac": "NP_001245928", "gene_names_uniprotkb": "milt; 2L6; CG13777; CG31630; CG43227; Dmel\\CG43227; Dmel_CG43227; Milton; Milt; anon-WO0153538.19; dmilton; l(2)k04704", "gene_names_refseq": "2L6; CG13777; CG31630; CG43227; Dmel\\CG43227; Milton; Milt; anon-WO0153538.19; dmilton; l(2)k04704; milt", "protein_names_uniprotkb": "Trafficking kinesin-binding protein milt; Protein milton", "protein_names_refseq": "CG43227-PE; milt-PE; milton, isoform E; milton", "tax_id": 7227, "disease": "developmental and epileptic encephalopathy 68 (Disease Ontology:DOID:0112204); Huntington's disease (Disease Ontology:DOID:12858); neurodegenerative disease (Disease Ontology:DOID:1289); Stiff-Person syndrome (Disease Ontology:DOID:13366)", "pathway": " (dme:Dmel_CG43227); (R-DME-9013419); (R-DME-9013425)", "pathway_count": 3, "publication_count": 19, "publication_id_list": "10731132;12495622;12537568;12537569;12537572;12537573;12537574;16110336;16717129;16887820;17372656;17569856;17569867;18327897;22425156;24995978;25589440;26109356;26109357", "class_list": "", "function": "Required for kinesin-mediated axonal transport of mitochondria to nerve terminals (PubMed:12495622, PubMed:16717129, PubMed:16887820). The oocyte acquires the majority of its mitochondria by competitive bidirectional transport along microtubules mediated by the Milton adapter. Mitochondria enter the young oocyte en mass from interconnected germ cells to generate the large aggregate known as the Balbiani body (PubMed:16887820). Milt and Miro form an essential protein complex that links Khc to mitochondria for light chain-independent, anterograde transport of mitochondria (PubMed:16717129)., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "Q0E8S6;Q8SWX2;Q95NI8", "ec_number_list": "", "go_molecular_function": "GO:0030674 protein-macromolecule adaptor activity;GO:0017022 myosin binding", "go_cellular_component": "GO:0005739 mitochondrion;GO:0031410 cytoplasmic vesicle;GO:1904115 axon cytoplasm", "go_biological_process": "GO:0030382 sperm mitochondrion organization;GO:0006605 protein targeting;GO:0048311 mitochondrion distribution;GO:0047496 vesicle transport along microtubule;GO:0051654 establishment of mitochondrion localization", "synthesized_glycan_count": 0, "hit_score": 2.0, "record_id": "Q960V3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q7K237-1", "uniprot_id": "C1GLT_DROME", "mass": 44323.0, "length": 388, "protein_name": "Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1", "gene_name": "C1GalTA", "organism": "Fruit fly", "refseq_name": "core 1 galactosyltransferase A, isoform B", "refseq_ac": "NP_609258", "gene_names_uniprotkb": "C1GalTA; C1GALT1; C1GalT1; C1beta3GalT1; CG9520; Dmel\\CG9520; Dmel_CG9520; anon-WO0144478.18; dC1GalT1; dC1GalT; dC1beta3GalT1", "gene_names_refseq": "C1GALT1; C1GalT1; C1GalTA; C1beta3GalT1; CG9520; Dmel\\CG9520; anon-WO0144478.18; dC1GalT1; dC1GalT; dC1beta3GalT1", "protein_names_uniprotkb": "Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1; 2.4.1.122; C1GalT1; Core 1 O-glycan T-synthase; Core 1 UDP-galactose:N-acetylgalactosamine-alpha-R beta 1,3-galactosyltransferase 1; Core 1 beta1,3-galactosyltransferase 1; Core 1 beta3-Gal-T1", "protein_names_refseq": "C1GalTA-PB; CG9520-PB; core 1 beta1,3-galactosyltransferase; core 1 galactosyltransferase A, isoform B", "tax_id": 7227, "disease": "autoimmune disease of blood (Disease Ontology:DOID:0060050)", "pathway": " (dme:Dmel_CG9520); (R-DME-913709)", "pathway_count": 2, "publication_count": 15, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;18985719;25589440;26109356;26109357;31719620;35504880", "class_list": "", "function": "Glycosyltransferase that generates the core 1 O-glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins., [UniProtKB, PubMed, PubMed, PubMed, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 6, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A4V0G7", "ec_number_list": "2.4.1.122", "go_molecular_function": "GO:0030145 manganese ion binding;GO:0042803 protein homodimerization activity;GO:0000166 nucleotide binding;GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity;GO:0048531 beta-1,3-galactosyltransferase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0016020 membrane", "go_biological_process": "GO:0021551 central nervous system morphogenesis;GO:1902037 negative regulation of hematopoietic stem cell differentiation;GO:0007528 neuromuscular junction development;GO:0016266 protein O-linked glycosylation via N-acetyl-galactosamine;GO:0009247 glycolipid biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "Q7K237-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q7JZB4-1", "uniprot_id": "GMPPB_DROME", "mass": 40448.0, "length": 369, "protein_name": "Mannose-1-phosphate guanylyltransferase catalytic subunit beta", "gene_name": "Gmppb", "organism": "Fruit fly", "refseq_name": "GDP-mannose pyrophosphorylase B, isoform D", "refseq_ac": "NP_001189177", "gene_names_uniprotkb": "Gmppb; CG1129; Dmel\\CG1129; Dmel_CG1129", "gene_names_refseq": "CG1129; Dmel\\CG1129; Gmppb", "protein_names_uniprotkb": "Mannose-1-phosphate guanylyltransferase catalytic subunit beta; 2.7.7.13; GDP-mannose pyrophosphorylase B; GTP-mannose-1-phosphate guanylyltransferase beta", "protein_names_refseq": "CG1129-PD; GDP-mannose pyrophosphorylase B, isoform D; Gmppb-PD", "tax_id": 7227, "disease": "autosomal recessive limb-girdle muscular dystrophy type 2T (Disease Ontology:DOID:0110294); congenital muscular dystrophy-dystroglycanopathy type A14 (Disease Ontology:DOID:0111233); muscular dystrophy-dystroglycanopathy (Disease Ontology:DOID:0112374); muscular dystrophy-dystroglycanopathy type B14 (Disease Ontology:DOID:0112377)", "pathway": " (dme:Dmel_CG1129); (R-DME-446205)", "pathway_count": 2, "publication_count": 13, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;15952742;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "Catalytic subunit of the GMPPA-GMPPB mannose-1-phosphate guanylyltransferase complex (By similarity). Catalyzes the formation of GDP-mannose, an essential precursor of glycan moieties of glycoproteins and glycolipids (By similarity). Can catalyze the reverse reaction in vitro (By similarity). Together with GMPPA regulates GDP-alpha-D-mannose levels (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.7.13", "go_molecular_function": "GO:0004475 mannose-1-phosphate guanylyltransferase (GTP) activity;GO:0005525 GTP binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0120508 GDP-mannose pyrophosphorylase complex", "go_biological_process": "GO:0009298 GDP-mannose biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "Q7JZB4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q86DS1-1", "uniprot_id": "F10A2_DROME", "mass": 41037.0, "length": 377, "protein_name": "Hsc70-interacting protein 2", "gene_name": "HIP-R", "organism": "Fruit fly", "refseq_name": "Hsc/Hsp70-interacting protein related, isoform D", "refseq_ac": "NP_001014719", "gene_names_uniprotkb": "HIP-R; CG2947; Dmel\\CG2947; Dmel_CG2947; Hip; anon-EST:fe1A9", "gene_names_refseq": "CG2947; Dmel\\CG2947; HIP-R; Hip; anon-EST:fe1A9", "protein_names_uniprotkb": "Hsc70-interacting protein 2; HIP-replacement", "protein_names_refseq": "CG2947-PD; HIP-R-PD; Hsc/Hsp70-interacting protein related, isoform D; anon-fast-evolving-1A9", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG2947); (dme:Dmel_CG32789); (R-DME-3371453)", "pathway_count": 3, "publication_count": 14, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17372656;17569856;17569867;19333534;25589440;26109356;26109357", "class_list": "", "function": "One HIP oligomer binds the ATPase domains of at least two HSC70 molecules dependent on activation of the HSC70 ATPase by HSP40. Stabilizes the ADP state of HSC70 that has a high affinity for substrate protein. Through its own chaperone activity, it may contribute to the interaction of HSC70 with various target proteins., [UniProtKB, UniProtKB]; One HIP oligomer binds the ATPase domains of at least two Hsc70 molecules dependent on activation of the Hsc70 ATPase by Hsp40. Stabilizes the ADP state of Hsc70 that has a high affinity for substrate protein. Through its own chaperone activity, it may contribute to the interaction of Hsc70 with various target proteins (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "C0L9I4;C0L9I8;Q86DR2;Q86DR3;Q86DR4;Q86DR5;Q86DR6;Q86DR7;Q86DR8;Q86DR9;Q86DS0;Q86DS2;Q86DS3;Q8IRT4", "ec_number_list": "", "go_molecular_function": "GO:0046983 protein dimerization activity;GO:0051087 protein-folding chaperone binding;GO:0031072 heat shock protein binding;GO:0030544 Hsp70 protein binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0032991 protein-containing complex;GO:1902494 catalytic complex", "go_biological_process": "GO:0006457 protein folding", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "Q86DS1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q8IMC6-1", "uniprot_id": "ASATR_DROME", "mass": 138828.0, "length": 1262, "protein_name": "Tau-tubulin kinase homolog Asator", "gene_name": "Asator", "organism": "Fruit fly", "refseq_name": "asator, isoform E", "refseq_ac": "NP_726576", "gene_names_uniprotkb": "Asator; CG11533; CK I; CKI-like; Dmel\\CG11533; Dmel_CG11533", "gene_names_refseq": "Asator; CG11533; CK I; CKI-like; Dmel\\CG11533", "protein_names_uniprotkb": "Tau-tubulin kinase homolog Asator; 2.7.11.1", "protein_names_refseq": "Asator-PE; CG11533-PE; asator, isoform E", "tax_id": 7227, "disease": "spinocerebellar ataxia 11 (Disease Ontology:DOID:0050961)", "pathway": " (dme:Dmel_CG11533)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;19890914;25589440;26109356;26109357", "class_list": "", "function": "Probable serine/threonine protein kinase., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q8IMC5", "ec_number_list": "2.7.11.17;2.7.11.1;2.7.11.13;2.7.11.24;2.7.11.22;2.7.11.21;5.6.1.8;2.7.11.11;2.7.11.23;2.7.12.1;2.7.11.25;2.7.11.12;2.7.12.2;2.7.10.2;2.7.11.39", "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005819 spindle", "go_biological_process": "GO:0007165 signal transduction", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "Q8IMC6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P91685-1", "uniprot_id": "GRM_DROME", "mass": 108486.0, "length": 976, "protein_name": "Metabotropic glutamate receptor", "gene_name": "mGluR", "organism": "Fruit fly", "refseq_name": "metabotropic glutamate receptor, isoform B", "refseq_ac": "NP_001259076", "gene_names_uniprotkb": "mGluR; CAA67993.1_Dr; CG11144; DmGlu-A; DmGlu-RA; DmGluAR; DmGluA; DmGluRA; DmGluR[[A]]; DmGluR; DmGlu[[A]]R; Dmel\\CG11144; Dmel_CG11144; FBgn0019985; Glu-RA; GluRA; GluR; dmGluRA; mGLuR; mGluRA; mGlurA", "gene_names_refseq": "CAA67993.1_Dr; CG11144; DmGlu-A; DmGlu-RA; DmGluAR; DmGluA; DmGluRA; DmGluR[[A]]; DmGluR; DmGlu[[A]]R; Dmel\\CG11144; FBgn0019985; Glu-RA; GluR; dmGluRA; mGLuR; mGluRA; mGluR; mGlurA", "protein_names_uniprotkb": "Metabotropic glutamate receptor; DmGluRA", "protein_names_refseq": "CG11144-PB; mGluR-PB; mGluRA; metabotropic glutamate receptor, isoform B; metabotropic glutamate receptor", "tax_id": 7227, "disease": "schizophrenia (Disease Ontology:DOID:5419); heroin dependence (Disease Ontology:DOID:9976)", "pathway": " (dme:Dmel_CG11144); (R-DME-418594); (R-DME-420499)", "pathway_count": 3, "publication_count": 15, "publication_id_list": "10731132;10821630;11536189;12537568;12537572;12537573;12537574;16110336;17569856;17569867;17893096;25589440;26109356;26109357;8824309", "class_list": "", "function": "G protein-coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors., [UniProtKB, PubMed, PubMed]; G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors., [UniProtKB, UniProtKB]", "predicted_glycosites": 6, "predicted_n_glycosites": 6, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 1, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 1, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 1, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 7, "binding_glycan_count": 0, "secondary_ac_list": "Q9V485", "ec_number_list": "", "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0015485 cholesterol binding;GO:0016595 glutamate binding;GO:0001641 group II metabotropic glutamate receptor activity;GO:0008066 glutamate receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane;GO:0045121 membrane raft;GO:0038038 G protein-coupled receptor homodimeric complex", "go_biological_process": "GO:0008049 male courtship behavior;GO:0072553 terminal button organization;GO:0007528 neuromuscular junction development;GO:0007612 learning;GO:0007614 short-term memory", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "P91685-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q05825-1", "uniprot_id": "ATPB_DROME", "mass": 54108.0, "length": 505, "protein_name": "ATP synthase subunit beta, mitochondrial", "gene_name": "ATPsynbeta", "organism": "Fruit fly", "refseq_name": "ATP synthase, beta subunit, isoform D", "refseq_ac": "NP_001284719", "gene_names_uniprotkb": "ATPsynbeta; ATP syn-beta; ATP-B; ATP-syn-B; ATP-syn-beta; ATP-synbeta; ATP5B; ATP5F1B; ATP5beta; ATPB; ATPase beta; ATPase-beta; ATPasebeta; ATPsyn b; ATPsyn-beta; ATPsyn-b; ATPsyn; ATP; CG11154; Comp V beta; Dmel\\CG11154; Dmel_CG11154; beta-ATPase; complex Vbeta; dATP5B", "gene_names_refseq": "ATP syn-beta; ATP-B; ATP-syn-B; ATP-syn-beta; ATP-synbeta; ATP5B; ATP5F1B; ATP5beta; ATPB; ATPase beta; ATPase-beta; ATPasebeta; ATPsyn b; ATPsyn-beta; ATPsyn-b; ATPsynbeta; ATPsyn; ATP; CG11154; Comp V beta; Dmel\\CG11154; beta-ATPase; complex Vbeta; dATP5B", "protein_names_uniprotkb": "ATP synthase subunit beta, mitochondrial; 7.1.2.2", "protein_names_refseq": "ATP synthase beta chain; ATP synthase beta subunit; ATP synthase beta-subunit; ATP synthase subunit beta, mitochondrial; ATP synthase subunits beta; ATP synthase, beta subunit, isoform D; ATP synthase-beta; ATPsynbeta-PD; CG11154-PD; F0/F1 ATP synthase beta; F1ATP synthase; H+-ATPase beta subunit; beta-F1-ATPase; complex V beta; mitochondrial ATPsynbeta", "tax_id": 7227, "disease": "cardiomyopathy (Disease Ontology:DOID:0050700); polycystic ovary syndrome (Disease Ontology:DOID:11612); transient cerebral ischemia (Disease Ontology:DOID:224); type 2 diabetes mellitus (Disease Ontology:DOID:9352); obesity (Disease Ontology:DOID:9970)", "pathway": " (dme:Dmel_CG11154); (R-DME-1268020); (R-DME-163210); (R-DME-8949613); (R-DME-9837999)", "pathway_count": 5, "publication_count": 14, "publication_id_list": "10071211;10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357;8373413", "class_list": "", "function": "Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Subunits alpha and beta form the catalytic core in F(1). Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits., [UniProtKB]; Produces ATP from ADP in the presence of a proton gradient across the membrane., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9V494", "ec_number_list": "2.7.1.23;1.1.1.40;1.1.1.38;1.1.1.39;1.2.4.2;1.1.1.35;1.1.1.-;1.1.1.62;1.1.1.51;1.1.1.53;2.3.1.37;3.5.3.1;7.1.2.2;1.4.1.3;2.7.11.2;2.7.11.-;1.2.4.1;3.4.21.53;7.1.1.2;6.2.1.4;3.4.24.-;4.98.1.1;1.-.-.-;1.1.1.239;1.1.1.37;2.5.1.39;4.2.1.3;3.4.21.92;5.6.2.3;1.2.1.3;6.1.1.5;1.8.1.4;1.3.8.1;1.3.8.5;1.1.1.41;2.3.1.-;2.8.3.5;2.3.-.-;2.3.1.9;4.2.1.2;2.3.3.16;5.3.3.21", "go_molecular_function": "GO:0005524 ATP binding;GO:0046933 proton-transporting ATP synthase activity, rotational mechanism", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane;GO:0045259 proton-transporting ATP synthase complex", "go_biological_process": "GO:0015986 proton motive force-driven ATP synthesis;GO:0042776 proton motive force-driven mitochondrial ATP synthesis", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "Q05825-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q8MQI6-1", "uniprot_id": "ELOF1_DROME", "mass": 9565.0, "length": 82, "protein_name": "Transcription elongation factor 1 homolog", "gene_name": "BcDNA:RE67573", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform C", "refseq_ac": "NP_001104426", "gene_names_uniprotkb": "BcDNA:RE67573; CG40228; Dmel\\CG40228; Dmel_CG40228", "gene_names_refseq": "BcDNA:RE67573; CG40228; Dmel\\CG40228", "protein_names_uniprotkb": "Transcription elongation factor 1 homolog", "protein_names_refseq": "CG40228-PC; uncharacterized protein, isoform C", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG40228)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A8Y556;A8Y557;Q7PL43", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000993 RNA polymerase II complex binding", "go_cellular_component": "GO:0008023 transcription elongation factor complex;GO:0005634 nucleus", "go_biological_process": "GO:0006368 transcription elongation by RNA polymerase II;GO:0006351 DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "Q8MQI6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q8T079-1", "uniprot_id": "GLYR1_DROME", "mass": 65252.0, "length": 602, "protein_name": "Cytokine-like nuclear factor N-PAC", "gene_name": "Ndf", "organism": "Fruit fly", "refseq_name": "Nucleosome-destabilizing factor, isoform C", "refseq_ac": "NP_001285791", "gene_names_uniprotkb": "Ndf; BEST:GH19401; BEST:LD22483; BEST:LD29743; CG4747; Dm_AI388468; Dmel\\CG4747; Dmel_CG4747; LD29743; NDF; dNDF", "gene_names_refseq": "BEST:GH19401; BEST:LD22483; BEST:LD29743; CG4747; Dm_AI388468; Dmel\\CG4747; LD29743; NDF; Ndf; dNDF", "protein_names_uniprotkb": "Cytokine-like nuclear factor N-PAC; Glyoxylate reductase 1 homolog; NPAC; Nuclear protein NP60 homolog; Nucleosome-destabilizing factor; Putative oxidoreductase GLYR1 homolog", "protein_names_refseq": "CG4747-PC; Ndf-PC; Nucleosome-destabilizing factor, isoform C; nucleosome-destabilizing factor", "tax_id": 7227, "disease": "atrioventricular septal defect (Disease Ontology:DOID:0050651)", "pathway": " (dme:Dmel_CG4747)", "pathway_count": 1, "publication_count": 15, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;18327897;23295261;25589440;26109356;26109357;29759984", "class_list": "", "function": "Nucleosome-destabilizing factor that is recruited to genes during transcriptional activation and colocalizes with a subset of trimethylated 'Lys-36' histone H3 (H3K36me3)-enriched regions (PubMed:23295261, PubMed:29759984). Binds DNA (in vitro) (PubMed:29759984). Facilitates Pol II transcription through nucleosomes (PubMed:29759984). Facilitates male-specific lethal (MSL) histone acetyltransferase complex targeting to active genes on the X chromosome (PubMed:23295261). Stimulates the acetylation of 'Lys-56' of nucleosomal histone H3 (H3K56ac) by nej (PubMed:29759984). May have oxidoreductase activity (By similarity)., [UniProtKB, UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9VL51", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0003682 chromatin binding;GO:0051287 NAD binding;GO:0031491 nucleosome binding;GO:0050661 NADP binding", "go_cellular_component": "GO:0000785 chromatin;GO:0005705 polytene chromosome interband;GO:0005694 chromosome", "go_biological_process": "GO:0009047 dosage compensation by hyperactivation of X chromosome;GO:0140673 transcription elongation-coupled chromatin remodeling", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "Q8T079-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P48593-1", "uniprot_id": "E631_DROME", "mass": 21995.0, "length": 193, "protein_name": "Calcium-binding protein E63-1", "gene_name": "Eip63F-1", "organism": "Fruit fly", "refseq_name": "Ecdysone-induced protein 63F 1, isoform A", "refseq_ac": "NP_524902", "gene_names_uniprotkb": "Eip63F-1; 63F-1; CBP12; CG15855; Ca[2+] binding protein; Dmel\\CG15855; Dmel_CG15855; E63-1; E63F; Eip63-1; Eip63F1; Eip63Fa; eip63F-1", "gene_names_refseq": "63F-1; CBP12; CG15855; Ca[2+] binding protein; Dmel\\CG15855; E63-1; E63F; Eip63-1; Eip63F-1; Eip63F1; Eip63Fa; eip63F-1", "protein_names_uniprotkb": "Calcium-binding protein E63-1", "protein_names_refseq": "CG15855-PA; Ecdysone-induced protein 63F 1, isoform A; Eip63F-1-PA", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG15855); (R-DME-6798695)", "pathway_count": 2, "publication_count": 12, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357;7671827", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9I7T4;Q9VZL0", "ec_number_list": "", "go_molecular_function": "GO:0005509 calcium ion binding;GO:0030234 enzyme regulator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005886 plasma membrane", "go_biological_process": "GO:0000226 microtubule cytoskeleton organization", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "P48593-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q8SXX4-1", "uniprot_id": "CAPON_DROME", "mass": 77280.0, "length": 698, "protein_name": "Capon-like protein", "gene_name": "CG34272", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform B", "refseq_ac": "NP_729509", "gene_names_uniprotkb": "CG34272; BcDNA:RE71517; BcDNA:RE71585; CG14178; CG17357; CG3179; CG32048; CG42673; Dm_3L:44995; Dmel\\CG42673; Dmel_CG42673", "gene_names_refseq": "BcDNA:RE71517; BcDNA:RE71585; CG14178; CG17357; CG3179; CG32048; CG34272; CG42673; Dm_3L:44995; Dmel\\CG42673", "protein_names_uniprotkb": "Capon-like protein", "protein_names_refseq": "CG42673-PB; uncharacterized protein, isoform B", "tax_id": 7227, "disease": "nephrotic syndrome type 22 (Disease Ontology:DOID:0112268); sciatic neuropathy (Disease Ontology:DOID:11446); Duchenne muscular dystrophy (Disease Ontology:DOID:11723); depressive disorder (Disease Ontology:DOID:1596); congestive heart failure (Disease Ontology:DOID:6000)", "pathway": " (dme:Dmel_CG42673)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "10731132;12505997;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "Putative adapter protein., [UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "Q9VT10;Q9VT12", "ec_number_list": "", "go_molecular_function": "GO:0050998 nitric-oxide synthase binding", "go_cellular_component": "GO:0098978 glutamatergic synapse", "go_biological_process": "GO:0098974 postsynaptic actin cytoskeleton organization", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "Q8SXX4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P37193-1", "uniprot_id": "ADXH1_DROME", "mass": 19734.0, "length": 172, "protein_name": "Adrenodoxin-like protein 1, mitochondrial", "gene_name": "Fdx1", "organism": "Fruit fly", "refseq_name": "ferredoxin 1, isoform B", "refseq_ac": "NP_001189075", "gene_names_uniprotkb": "Fdx1; BcDNA:RH67819; CG4205; Dmel\\CG4205; Dmel_CG4205; Fdxh", "gene_names_refseq": "BcDNA:RH67819; CG4205; Dmel\\CG4205; Fdx1; Fdxh", "protein_names_uniprotkb": "Adrenodoxin-like protein 1, mitochondrial; Ferredoxin-1", "protein_names_refseq": "CG4205-PB; Fdx1-PB; ferredoxin 1, isoform B; ferredoxin", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG4205); (R-DME-1362409); (R-DME-2395516)", "pathway_count": 3, "publication_count": 14, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;25589440;25628335;26109356;26109357;3123699", "class_list": "", "function": "Required for ecdysteroidogenesis in the prothoracic gland which is necessary for larval to pupal transition., [UniProtKB, PubMed, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q8MYT2;Q9VSW8", "ec_number_list": "", "go_molecular_function": "GO:0009055 electron transfer activity;GO:0046872 metal ion binding;GO:0051537 2 iron, 2 sulfur cluster binding", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0016226 iron-sulfur cluster assembly;GO:0006694 steroid biosynthetic process;GO:0006744 ubiquinone biosynthetic process;GO:0022900 electron transport chain;GO:0044571 [2Fe-2S] cluster assembly", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "P37193-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q24142-1", "uniprot_id": "HR78_DROME", "mass": 65393.0, "length": 601, "protein_name": "Nuclear hormone receptor HR78", "gene_name": "Hr78", "organism": "Fruit fly", "refseq_name": "Hormone-receptor-like in 78, isoform E", "refseq_ac": "NP_001189151", "gene_names_uniprotkb": "Hr78; CG7199; DHR78; Dhr78; Dmel\\CG7199; Dmel_CG7199; F; HR78; Hr78D; NR2D1", "gene_names_refseq": "CG7199; DHR78; Dhr78; Dmel\\CG7199; HR78; Hr78D; Hr78; NR2D1; XR78E/F", "protein_names_uniprotkb": "Nuclear hormone receptor HR78; Nuclear receptor XR78E/F; Nuclear receptor subfamily 2 group D member 1; dHR78", "protein_names_refseq": "CG7199-PE; Hormone-receptor-like in 78, isoform E; Hr78-PE; X receptor at 78E/F", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG7199); (R-DME-383280); (R-DME-9940951)", "pathway_count": 3, "publication_count": 16, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;14599492;16110336;17569856;17569867;18327897;25589440;26109356;26109357;7479823;7479849", "class_list": "", "function": "Binds to direct repeats of the sequence 5'-AGGTCA-3'. Inhibits the ecdysone response. Plays an essential role in regulating molting of the tracheal cuticle during larval development., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A4V288;Q24108;Q8IPT4;Q9VP28", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0004879 nuclear receptor activity;GO:0003700 DNA-binding transcription factor activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0030154 cell differentiation;GO:0050829 defense response to Gram-negative bacterium;GO:0006355 regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "Q24142-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q02280-1", "uniprot_id": "KCNAE_DROME", "mass": 126371.0, "length": 1174, "protein_name": "Potassium voltage-gated channel protein eag", "gene_name": "eag", "organism": "Fruit fly", "refseq_name": "ether a go-go, isoform A", "refseq_ac": "NP_511158", "gene_names_uniprotkb": "eag; CG10952; CIKE; Dmel\\CG10952; Dmel_CG10952; EAG; Eag", "gene_names_refseq": "CG10952; CIKE; Dmel\\CG10952; EAG; Eag; eag", "protein_names_uniprotkb": "Potassium voltage-gated channel protein eag; Ether-a-go-go protein", "protein_names_refseq": "CG10952-PA; eag-PA; ether a go-go, isoform A; ether-a go-go; ether-a-go-go; ether-a-gogo", "tax_id": 7227, "disease": "colorectal adenocarcinoma (Disease Ontology:DOID:0050861); developmental and epileptic encephalopathy (Disease Ontology:DOID:0112202); epilepsy (Disease Ontology:DOID:1826); renal cell carcinoma (Disease Ontology:DOID:4450); hepatocellular carcinoma (Disease Ontology:DOID:684)", "pathway": " (dme:Dmel_CG10952); (R-DME-1296072)", "pathway_count": 2, "publication_count": 16, "publication_id_list": "10731132;10934243;11517334;11980904;12537568;12537572;12537573;12537574;15901771;16110336;17569856;17569867;1840699;25589440;26109356;26109357", "class_list": "", "function": "Structural component of a potassium channel. Mediates the potassium permeability of membranes; potassium current is regulated by CaMKII and CASK. Has a role in growth of the perineurial glial layer of the larval peripheral nerve., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 5, "predicted_n_glycosites": 3, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "Q9VXZ6", "ec_number_list": "", "go_molecular_function": "GO:0044325 transmembrane transporter binding;GO:0005249 voltage-gated potassium channel activity;GO:0022843 voltage-gated monoatomic cation channel activity;GO:0005516 calmodulin binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0008076 voltage-gated potassium channel complex;GO:0034702 monoatomic ion channel complex;GO:0016020 membrane", "go_biological_process": "GO:0007611 learning or memory;GO:0007612 learning;GO:0042391 regulation of membrane potential;GO:0008016 regulation of heart contraction;GO:0006813 potassium ion transport", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "Q02280-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q8MQJ9-1", "uniprot_id": "BRAT_DROME", "mass": 110366.0, "length": 1037, "protein_name": "Protein brain tumor", "gene_name": "brat", "organism": "Fruit fly", "refseq_name": "brain tumor, isoform F", "refseq_ac": "NP_001286083", "gene_names_uniprotkb": "brat; BRAT; Brat; CG10719; Cf; Dmel\\CG10719; Dmel_CG10719; E60; anon-37CDa; fs(2)ltoPM43; l(2)37Cf; l(2)E60; l(2)brat; lincRNA.S1565", "gene_names_refseq": "BRAT; Brat; CG10719; Cf; Dmel\\CG10719; E60; anon-37CDa; brat; fs(2)ltoPM43; l(2)37Cf; l(2)E60; l(2)brat; lincRNA.S1565", "protein_names_uniprotkb": "Protein brain tumor", "protein_names_refseq": "CG10719-PF; brain tumor, isoform F; brain tumor; brain tumour; brat-PF", "tax_id": 7227, "disease": "neurodegenerative disease (Disease Ontology:DOID:1289); brain cancer (Disease Ontology:DOID:1319); cancer (Disease Ontology:DOID:162)", "pathway": " (dme:Dmel_CG10719)", "pathway_count": 1, "publication_count": 24, "publication_id_list": "10731132;10949924;11274060;11807032;12537568;12537569;12537572;12537573;12537574;14561773;16110336;16120803;16564014;17569856;17569867;18342578;18528333;22143802;24550111;24990993;25589440;26109356;26109357;38225354", "class_list": "", "function": "A NHL-domain family protein that functions as a translational repressor to inhibit cell proliferation (PubMed:11274060). Plays a central role in translation repression of hb mRNA by being recruited by nanos (nos) and pum to the Nanos Response Element (NRE), a 16 bp sequence in the hb mRNA 3'-UTR (PubMed:11274060). Probably recruited by other proteins to repress translation of other mRNAs in other tissues (PubMed:11274060). Negatively regulates expression of Myc in a 3'-UTR dependent manner in both neural progenitor and epithelial cells (PubMed:24990993). Regulates expression of mei-P26, possibly at transcriptional level (PubMed:24990993). Involved in the regulation of ribosomal RNA synthesis and cell growth (PubMed:11807032). Participates in abdominal segmentation and imaginal disk development (PubMed:11274060). During neuroblast division, segregates asymmetrically and inhibits self-renewal of one of the two daughter cells (PubMed:16564014). Together with the asymmetrically segregating transcription factor prospero ensures that the daughter cell will stop growing, exit the cell cycle, and differentiate into neurons possibly by modulating the function of dm in ganglion mother cells (GMC) (PubMed:11807032, PubMed:16564014). Restricts developmental potential of type II intermediary neuronal progenitor (INP) cells playing a role in proliferation and maturation of the neuroblasts (PubMed:14561773, PubMed:18342578, PubMed:22143802, PubMed:24550111)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 8, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A4V0U9;Q0E8P2;Q2XXZ6;Q8MR02;Q9U633;Q9U634;Q9U635;Q9U636;Q9Y1W4", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0030371 translation repressor activity;GO:0003730 mRNA 3'-UTR binding;GO:0045182 translation regulator activity", "go_cellular_component": "GO:0045180 basal cortex;GO:0045179 apical cortex;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0043025 neuronal cell body", "go_biological_process": "GO:0014016 neuroblast differentiation;GO:0007402 ganglion mother cell fate determination;GO:0006417 regulation of translation;GO:0008285 negative regulation of cell population proliferation;GO:0010629 negative regulation of gene expression", "synthesized_glycan_count": 0, "hit_score": 2.5, "record_id": "Q8MQJ9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P33438-1", "uniprot_id": "GLT_DROME", "mass": 118749.0, "length": 1026, "protein_name": "Glutactin", "gene_name": "Glt", "organism": "Fruit fly", "refseq_name": "glutactin, isoform D", "refseq_ac": "NP_001245946", "gene_names_uniprotkb": "Glt; CG9280; CT26441; Dmel\\CG9280; Dmel_CG9280; glt", "gene_names_refseq": "CG9280; CT26441; Dmel\\CG9280; Glt; glt", "protein_names_uniprotkb": "Glutactin", "protein_names_refseq": "CG9280-PD; Glt-PD; glutactin, isoform D; glutactin", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG9280)", "pathway_count": 1, "publication_count": 15, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;2108864;25589440;26109356;26109357;33925313;40245499", "class_list": "", "function": "Not known. Binds calcium ions., [UniProtKB]", "predicted_glycosites": 4, "predicted_n_glycosites": 4, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 2, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 2, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 2, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "A4V0G5;Q9VLJ3", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005615 extracellular space;GO:0005604 basement membrane;GO:0031983 vesicle lumen;GO:0005576 extracellular region", "go_biological_process": "GO:0098542 defense response to other organism;GO:0008045 motor neuron axon guidance;GO:0016201 synaptic target inhibition;GO:0042381 hemolymph coagulation", "synthesized_glycan_count": 0, "hit_score": 1.9, "record_id": "P33438-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P48608-1", "uniprot_id": "DIA_DROME", "mass": 123171.0, "length": 1091, "protein_name": "Protein diaphanous", "gene_name": "dia", "organism": "Fruit fly", "refseq_name": "diaphanous, isoform E", "refseq_ac": "NP_001260640", "gene_names_uniprotkb": "dia; 38E.16; CG1768; DIA; Diaphanous; Dias; Dia; Dmel\\CG1768; Dmel_CG1768; l(2)k07135; ms(2)04138", "gene_names_refseq": "38E.16; CG1768; DIA; Diaphanous; Dias; Dia; Dmel\\CG1768; dia; l(2)k07135; ms(2)04138", "protein_names_uniprotkb": "Protein diaphanous", "protein_names_refseq": "CG1768-PE; dia-PE; diaphanous, isoform E; diaphanous", "tax_id": 7227, "disease": "autosomal dominant auditory neuropathy 1 (Disease Ontology:DOID:0060690); primary ovarian insufficiency 2A (Disease Ontology:DOID:0080858); autosomal dominant nonsyndromic deafness 1 (Disease Ontology:DOID:0110541); sensorineural hearing loss (Disease Ontology:DOID:10003); microcephaly (Disease Ontology:DOID:10907); congenital dyserythropoietic anemia (Disease Ontology:DOID:1338); primary ovarian insufficiency (Disease Ontology:DOID:5426)", "pathway": " (dme:Dmel_CG1768); (R-DME-5663220); (R-DME-6785631); (R-DME-6798695); (R-DME-8980692); (R-DME-9013149); (R-DME-9013406); (R-DME-9013423); (R-DME-9035034)", "pathway_count": 9, "publication_count": 14, "publication_id_list": "10731132;10751177;12537568;12537572;12537573;12537574;16110336;17569856;17569867;23853710;25589440;26109356;26109357;7821209", "class_list": "", "function": "Required for cytokinesis in both mitosis and meiosis. Has a role in actin cytoskeleton organization and is essential for many, if not all, actin-mediated events involving membrane invagination. May serve as a mediator between signaling molecules and actin organizers at specific phases of the cell cycle. Possible component of the contractile ring or may control its function., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 7, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q5BI26;Q9VIJ7", "ec_number_list": "", "go_molecular_function": "GO:0003779 actin binding;GO:0005546 phosphatidylinositol-4,5-bisphosphate binding;GO:0031267 small GTPase binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005856 cytoskeleton;GO:0005938 cell cortex;GO:0045177 apical part of cell;GO:0016324 apical plasma membrane", "go_biological_process": "GO:0032507 maintenance of protein location in cell;GO:0007015 actin filament organization;GO:0030036 actin cytoskeleton organization;GO:0090303 positive regulation of wound healing;GO:0007605 sensory perception of sound", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "P48608-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q7KU24-1", "uniprot_id": "CHD1_DROME", "mass": 211828.0, "length": 1883, "protein_name": "ATP-dependent chromatin remodeler Chd1", "gene_name": "Chd1", "organism": "Fruit fly", "refseq_name": "Chromodomain-helicase-DNA-binding protein 1, isoform A", "refseq_ac": "NP_477197", "gene_names_uniprotkb": "Chd1; 2; CG3733; CHD-1; CHD1; DmCHD1; Dmel\\CG3733; Dmel_CG3733; chd1; dCHD1; dChd1; l(2)23Cd", "gene_names_refseq": "2; CG3733; CHD-1; CHD1; Chd1; DmCHD1; Dmel\\CG3733; chd1; dCHD1; dChd1; l(2)23Cd", "protein_names_uniprotkb": "ATP-dependent chromatin remodeler Chd1; 3.6.4.-; Chd-1; Chromo domain-containing protein 1", "protein_names_refseq": "CG3733-PA; Chd1-PA; Chromodomain-helicase-DNA-binding protein 1, isoform A; Chromodomain-helicase-DNA-binding protein; chromo-ATPase/helicase-DNA-binding domain; chromo-ATPase/helicase-DNA-binding protein 1; lethal (2) 23Cd", "tax_id": 7227, "disease": "CHARGE syndrome (Disease Ontology:DOID:0050834); autism spectrum disorder (Disease Ontology:DOID:0060041); myoclonic-atonic epilepsy (Disease Ontology:DOID:0060475); castration-resistant prostate carcinoma (Disease Ontology:DOID:0080909); developmental and epileptic encephalopathy 94 (Disease Ontology:DOID:0081325); prostate cancer (Disease Ontology:DOID:10283); epilepsy (Disease Ontology:DOID:1826)", "pathway": " (dme:Dmel_CG3733); (R-DME-9943411)", "pathway_count": 2, "publication_count": 17, "publication_id_list": "10199952;10731132;12537568;12537572;12537573;12537574;15643425;16110336;17351630;17569856;17569867;17717186;18202396;25589440;26109356;26109357;8692958", "class_list": "", "function": "ATP-dependent chromatin-remodeling factor which functions as substrate recognition component of the transcription regulatory histone acetylation (HAT) complex SAGA. Regulates polymerase II transcription. Also required for efficient transcription by RNA polymerase I, and more specifically the polymerase I transcription termination step. Regulates negatively DNA replication. Not only involved in transcription-related chromatin remodeling, but also required to maintain a specific chromatin configuration across the genome (By similarity). Involved in assembly of active chromatin. Required for maintaining open chromatin and pluripotency in embryonic stem cells and is important for wing development and fertility. Is essential for the incorporation of histone H3.3 and assembly of paternal chromatin. Required for replication-independent nucleosome assembly in the decondensing male pronucleus., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 7, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "Q24376;Q9VQJ9", "ec_number_list": "3.6.4.13;7.2.2.-;3.6.4.-;3.6.4.10;3.6.4.6;3.6.4.12;5.6.2.4;5.6.2.5;2.7.4.3;5.6.2.3;3.1.-.-;3.6.1.15;3.-.-.-;5.6.1.1;2.7.11.1;3.6.-.-;5.6.2.-", "go_molecular_function": "GO:0003677 DNA binding;GO:0003682 chromatin binding;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0042393 histone binding", "go_cellular_component": "GO:0005634 nucleus;GO:0000785 chromatin;GO:0005703 polytene chromosome puff;GO:0005705 polytene chromosome interband;GO:0005694 chromosome", "go_biological_process": "GO:0034728 nucleosome organization;GO:0006351 DNA-templated transcription;GO:0048477 oogenesis;GO:0007476 imaginal disc-derived wing morphogenesis;GO:0035041 sperm DNA decondensation", "synthesized_glycan_count": 0, "hit_score": 1.8, "record_id": "Q7KU24-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q05201-1", "uniprot_id": "EYA_DROME", "mass": 80657.0, "length": 766, "protein_name": "Protein phosphatase eya", "gene_name": "eya", "organism": "Fruit fly", "refseq_name": "eyes absent, isoform B", "refseq_ac": "NP_523492", "gene_names_uniprotkb": "eya; 24582246; BcDNA:LD16029; CG9554; CLIFT; CLI; Clift; Dmel\\CG9554; Dmel_CG9554; EY2-1; EYA; Eya; Eyes absent; cli[eya]; cli; dEYA; del1; eay; ey-2; eya", "gene_names_refseq": "24582246; BcDNA:LD16029; CG9554; CLIFT; CLI; Clift; Dmel\\CG9554; EY2-1; EYA; Eya; Eyes absent; cli/eya; cli[eya]; cli; dEYA; del1; eay; ey-2; eya", "protein_names_uniprotkb": "Protein phosphatase eya; 3.1.3.48; Developmental protein eyes absent; Protein Clift", "protein_names_refseq": "CG9554-PB; Eye absent; Eyes-absent; clift; delayed gonad formation 1; eya-PB; eyeless 2; eyes absent, isoform B; eyes absent", "tax_id": 7227, "disease": "branchiootic syndrome 1 (Disease Ontology:DOID:0061209); dilated cardiomyopathy 1J (Disease Ontology:DOID:0110440); autosomal dominant nonsyndromic deafness 10 (Disease Ontology:DOID:0110542); branchiootorenal syndrome 1 (Disease Ontology:DOID:0111423); sensorineural hearing loss (Disease Ontology:DOID:10003); otitis media (Disease Ontology:DOID:10754); dilated cardiomyopathy (Disease Ontology:DOID:12930); branchiootorenal syndrome (Disease Ontology:DOID:14702); eye disease (Disease Ontology:DOID:5614); congestive heart failure (Disease Ontology:DOID:6000); mitochondrial myopathy (Disease Ontology:DOID:699)", "pathway": " (dme:Dmel_CG9554); (R-DME-5693565)", "pathway_count": 2, "publication_count": 17, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;14628052;14628053;16110336;17569856;17569867;25589440;26109356;26109357;8431945;9428512;9428513", "class_list": "", "function": "Tyrosine phosphatase thought to play a role in transcription regulation during organogenesis through its intrinsic protein phosphatase activity (PubMed:14628052, PubMed:14628053). The phosphatase activity was shown in vitro. Appears to function together with So and Dac in eye development (PubMed:9428512, PubMed:9428513). Required for the survival of eye progenitor cells at a critical stage in morphogenesis (PubMed:8431945)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 5, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 11, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q961V4;Q9VMC1", "ec_number_list": "3.1.3.16;3.1.3.48;3.1.3.-;3.1.3.2;2.7.11.1;3.1.3.27;2.3.1.48;3.6.-.-", "go_molecular_function": "GO:0003713 transcription coactivator activity;GO:0046872 metal ion binding;GO:0004721 phosphoprotein phosphatase activity;GO:0004726 non-membrane spanning protein tyrosine phosphatase activity;GO:0004725 protein tyrosine phosphatase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0048749 compound eye development;GO:0006351 DNA-templated transcription;GO:0007283 spermatogenesis;GO:0010628 positive regulation of gene expression;GO:0030154 cell differentiation", "synthesized_glycan_count": 0, "hit_score": 1.8, "record_id": "Q05201-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q24093-1", "uniprot_id": "ABHD2_DROME", "mass": 45402.0, "length": 398, "protein_name": "Abhydrolase domain-containing protein 2", "gene_name": "Hydr2", "organism": "Fruit fly", "refseq_name": "alpha/beta hydrolase2, isoform B", "refseq_ac": "NP_001245852", "gene_names_uniprotkb": "Hydr2; C24; CG3488; CT11757; DMU29170; Dmel\\CG3488; Dmel_CG3488; HYDR2; anon-23Da; anon-23D; c24; cg3488", "gene_names_refseq": "C24; CG3488; CT11757; DMU29170; Dmel\\CG3488; HYDR2; Hydr2; anon-23Da; anon-23D; c24; cg3488", "protein_names_uniprotkb": "Abhydrolase domain-containing protein 2; 3.1.1.-", "protein_names_refseq": "CG3488-PB; Hydr2-PB; alpha/beta hydrolase2, isoform B", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG3488)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;12612838;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9VQM6", "ec_number_list": "", "go_molecular_function": "GO:0016298 lipase activity;GO:0047372 monoacylglycerol lipase activity;GO:0008126 acetylesterase activity", "go_cellular_component": "GO:0036126 sperm flagellum;GO:0097524 sperm plasma membrane;GO:0016020 membrane", "go_biological_process": "GO:0006629 lipid metabolic process;GO:0046464 acylglycerol catabolic process;GO:0043401 steroid hormone receptor signaling pathway;GO:0048240 sperm capacitation;GO:0051793 medium-chain fatty acid catabolic process", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "Q24093-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P45447-1", "uniprot_id": "E78C_DROME", "mass": 94747.0, "length": 862, "protein_name": "Ecdysone-induced protein 78C", "gene_name": "Eip78C", "organism": "Fruit fly", "refseq_name": "Ecdysone-induced protein 78C, isoform D", "refseq_ac": "NP_001246862", "gene_names_uniprotkb": "Eip78C; CG18023; DR-78; Dmel\\CG18023; Dmel_CG18023; E78A; E78B; E78D; E78; EIP78C; Eip 78C; Eip78D; Eip78c; Eip78; NR1E1; anon-WO0172774.42; anon-WO0172774.44; dE78; eip78c", "gene_names_refseq": "CG18023; DR-78; Dmel\\CG18023; E78A; E78B; E78D; E78; EIP78C; Eip 78C; Eip78C; Eip78D; Eip78c; Eip78; NR1E1; anon-WO0172774.42; anon-WO0172774.44; dE78; eip78c", "protein_names_uniprotkb": "Ecdysone-induced protein 78C; DR-78; Nuclear receptor subfamily 1 group E member 1", "protein_names_refseq": "CG18023-PD; Ecdysone-induced protein 78C, isoform D; Eip78C-PD; ecdysone induced protein 78C; nuclear hormone receptor", "tax_id": 7227, "disease": "atrioventricular septal defect (Disease Ontology:DOID:0050651)", "pathway": " (dme:Dmel_CG18023)", "pathway_count": 1, "publication_count": 14, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357;8241283;8402914;8878682", "class_list": "", "function": "Induces the early late puff 78C which triggers puparium formation and development., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "O18395;O18396;Q7KTW8;Q8IPT7;Q9NBW8;Q9NBW9;Q9VP64", "ec_number_list": "", "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0008270 zinc ion binding;GO:0043565 sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045892 negative regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "P45447-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q24312-1", "uniprot_id": "EWG_DROME", "mass": 77763.0, "length": 733, "protein_name": "DNA-binding protein Ewg", "gene_name": "ewg", "organism": "Fruit fly", "refseq_name": "erect wing, isoform G", "refseq_ac": "NP_001014707", "gene_names_uniprotkb": "ewg; CG3114; Dmel\\CG3114; Dmel_CG3114; EC3; EG:BACR37P7.7; EWG; Ewg; NRF-1; l(1)1Ag; l(1)DA659; l(1)EC3f; l(1)EC3; l(1)VA720; l[EC3]", "gene_names_refseq": "CG3114; Dmel\\CG3114; EC3; EG:BACR37P7.7; EWG; Ewg; NRF-1; ewg; l(1)1Ag; l(1)DA659; l(1)EC3f; l(1)EC3; l(1)VA720; l[EC3]", "protein_names_uniprotkb": "DNA-binding protein Ewg; Protein erect wing", "protein_names_refseq": "CG3114-PG; erect wing, isoform G; erect wings; ewg-PG", "tax_id": 7227, "disease": "Huntington's disease (Disease Ontology:DOID:12858)", "pathway": " (dme:Dmel_CG3114)", "pathway_count": 1, "publication_count": 15, "publication_id_list": "10330140;10731132;10731137;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357;8388540", "class_list": "", "function": "May function as a positive regulator of transcription in developing and differentiated neurons, regulating common aspects of neuronal differentiation and maintenance. Requirement in the CNS may be higher than in the peripheral system. Vital for development of the indirect flight muscles., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A4V3R8;Q59E73;Q59E74;Q59E75;Q59E76;Q59E77;Q8SXJ1;Q9NF76;Q9W5G8;Q9W5G9", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003700 DNA-binding transcription factor activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0007417 central nervous system development;GO:0007517 muscle organ development;GO:0090263 positive regulation of canonical Wnt signaling pathway", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "Q24312-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q7KW14-1", "uniprot_id": "CCDCX_DROME", "mass": 134461.0, "length": 1234, "protein_name": "Coiled-coil domain-containing protein CG32809", "gene_name": "CG3737; CG3783; CG3791; EG:73D1.1; EG:9D2.2", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform D", "refseq_ac": "NP_569934", "gene_names_uniprotkb": "CG3737; CG3783; CG3791; EG:73D1.1; EG:9D2.2; CG32809; CG3737; CG3783; CG3791; Dmel\\CG32809; Dmel_CG32809; EG:171E4.3; EG:73D1.1; EG:9D2.2", "gene_names_refseq": "CG32809; CG3737; CG3783; CG3791; Dmel\\CG32809; EG:171E4.3; EG:73D1.1; EG:9D2.2", "protein_names_uniprotkb": "Coiled-coil domain-containing protein CG32809", "protein_names_refseq": "CG32809-PD; uncharacterized protein, isoform D", "tax_id": 7227, "disease": "cocaine dependence (Disease Ontology:DOID:9975)", "pathway": " (dme:Dmel_CG32809)", "pathway_count": 1, "publication_count": 14, "publication_id_list": "10731132;10731137;12537568;12537569;12537572;12537573;12537574;16110336;17018572;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "O46062;O76897;O76919;Q8MR25;Q95R31;Q9W566", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "Q7KW14-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9U4H5-1", "uniprot_id": "TM2D3_DROME", "mass": 31364.0, "length": 284, "protein_name": "TM2 domain-containing protein almondex", "gene_name": "amx", "organism": "Fruit fly", "refseq_name": "almondex, isoform B", "refseq_ac": "NP_001245591", "gene_names_uniprotkb": "amx; BcDNA:GH02974; CG12127; Dmel\\CG12127; Dmel_CG12127; fs(1)amx", "gene_names_refseq": "BcDNA:GH02974; CG12127; Dmel\\CG12127; amx; fs(1)amx", "protein_names_uniprotkb": "TM2 domain-containing protein almondex; Beta-amyloid peptide binding-like protein amx; TM2D3; dBBP-like protein; dBLP", "protein_names_refseq": "CG12127-PB; almondex, isoform B; amx-PB", "tax_id": 7227, "disease": "Alzheimer's disease (Disease Ontology:DOID:10652)", "pathway": " (dme:Dmel_CG12127)", "pathway_count": 1, "publication_count": 17, "publication_id_list": "10731132;10731138;12537568;12537572;12537573;12537574;14595834;16110336;17569856;17569867;18331889;25589440;26109356;26109357;27764101;31782145;34905536", "class_list": "", "function": "Positive regulator of Notch signaling during lateral inhibition and boundary formation (PubMed:14595834, PubMed:18331889, PubMed:34905536). Interacts with Notch signaling at the membrane, at the level of gamma-secretase-mediated S3 cleavage (PubMed:18331889, PubMed:34905536). May regulate Notch signaling by regulating the subcellular localization of N/Notch in a context dependent manner (PubMed:31782145, PubMed:34905536). Maternal neurogenic factor involved in Notch signaling-dependent mesectodermal and neuroectodermal specification during early embryogenesis (PubMed:14595834, PubMed:18331889, PubMed:31782145, PubMed:34905536). Functions cooperatively with bisc/TM2D1 and amrt/TM2D2 (PubMed:34905536). Required for maintenance of neuronal function (PubMed:34905536). Involved in imaginal specification of eyes and wings (PubMed:18331889)., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 6, "predicted_n_glycosites": 6, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 6, "binding_glycan_count": 0, "secondary_ac_list": "Q9W361", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane;GO:0031982 vesicle;GO:0016020 membrane", "go_biological_process": "GO:0046331 lateral inhibition;GO:0007219 Notch signaling pathway;GO:0045747 positive regulation of Notch signaling pathway;GO:0007400 neuroblast fate determination;GO:0007498 mesoderm development", "synthesized_glycan_count": 0, "hit_score": 1.8, "record_id": "Q9U4H5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P32870-1", "uniprot_id": "CYA1_DROME", "mass": 248824.0, "length": 2248, "protein_name": "Adenylate cyclase 1", "gene_name": "Adcy1", "organism": "Fruit fly", "refseq_name": "rutabaga, isoform A", "refseq_ac": "NP_511156", "gene_names_uniprotkb": "Adcy1; AC; Ac12F; CG9533; Dmel\\CG9533; Dmel_CG9533; EP1603; RUT; Rut-AC; Rut; dADCY1; rut", "gene_names_refseq": "AC; Ac12F; CG9533; Dmel\\CG9533; EP1603; RUT; Rut-AC; Rut; dADCY1; rut", "protein_names_uniprotkb": "Adenylate cyclase 1; 4.6.1.1; ATP pyrophosphate-lyase; Ca(2+)/calmodulin-responsive adenylate cyclase; Protein rutabaga", "protein_names_refseq": "CG9533-PA; RUTABAGA; adenylyl cyclase; rut-PA; rutabaga, isoform A; rutabage", "tax_id": 7227, "disease": "autosomal recessive nonsyndromic deafness 44 (Disease Ontology:DOID:0110501); alcohol use disorder (Disease Ontology:DOID:1574)", "pathway": " (dme:Dmel_CG9533); (R-DME-163615); (R-DME-170660); (R-DME-170670); (R-DME-418597); (R-DME-5610787)", "pathway_count": 6, "publication_count": 13, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;1739965;17569856;17569867;21368057;25589440;26109356;26109357", "class_list": "", "function": "This is a membrane-bound, calmodulin-sensitive adenylyl cyclase. Inactivation of this cyclase leads to a learning and memory defect., [UniProtKB, PubMed]", "predicted_glycosites": 4, "predicted_n_glycosites": 2, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "Q9TWA7;Q9VY17", "ec_number_list": "4.6.1.1", "go_molecular_function": "GO:0004016 adenylate cyclase activity;GO:0005516 calmodulin binding;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane;GO:0045202 synapse", "go_biological_process": "GO:0006171 cAMP biosynthetic process;GO:0006979 response to oxidative stress;GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007274 neuromuscular synaptic transmission;GO:0007528 neuromuscular junction development", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "P32870-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P16914-1", "uniprot_id": "ELAV_DROME", "mass": 50817.0, "length": 483, "protein_name": "Protein elav", "gene_name": "elav", "organism": "Fruit fly", "refseq_name": "embryonic lethal abnormal vision, isoform B", "refseq_ac": "NP_001014713", "gene_names_uniprotkb": "elav; 44C11; 9F8A9; CG4262; Dmel\\CG4262; Dmel_CG4262; EC7; EG:65F1.2; ELAV; ELav; END1-2; ElaV; Elav-9F8A9; Elav; dHuR; elav-1; elav-2; elav-3; fliJ; l(1)1Be; l(1)EC7; l(1)G0031; l(1)G0319; weg", "gene_names_refseq": "44C11; 9F8A9; CG4262; Dmel\\CG4262; EC7; EG:65F1.2; ELAV; ELav; END1-2; ElaV; Elav-9F8A9; Elav; dHuR; elav-1; elav-2; elav-3; elav; fliJ; l(1)1Be; l(1)EC7; l(1)G0031; l(1)G0319; weg", "protein_names_uniprotkb": "Protein elav; Embryonic lethal abnormal visual protein", "protein_names_refseq": "CG4262-PB; elav-PB; embryonic lethal abnormal vision, isoform B; embryonic lethal abnormal vision; embryonic lethal abnormal visual system; embryonic lethal, abnormal vision; embryonically lethal abnormal vision; weniger", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG4262); (R-DME-450520)", "pathway_count": 2, "publication_count": 14, "publication_id_list": "10731132;10731137;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357;3144044", "class_list": "", "function": "Required for the proper development and maintenance of neurons presumably by affecting RNA metabolism., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q7K7L9;Q9V3F6", "ec_number_list": "", "go_molecular_function": "GO:0000900 mRNA regulatory element binding translation repressor activity;GO:0003723 RNA binding;GO:0003729 mRNA binding;GO:0008266 poly(U) RNA binding;GO:0140517 protein-RNA adaptor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0015030 Cajal body;GO:1990904 ribonucleoprotein complex", "go_biological_process": "GO:0009792 embryo development ending in birth or egg hatching;GO:0007399 nervous system development;GO:0007417 central nervous system development;GO:0007281 germ cell development;GO:0031441 negative regulation of mRNA 3'-end processing", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "P16914-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P14785-1", "uniprot_id": "CCNA_DROME", "mass": 56152.0, "length": 491, "protein_name": "G2/mitotic-specific cyclin-A", "gene_name": "CycA", "organism": "Fruit fly", "refseq_name": "cyclin A, isoform A", "refseq_ac": "NP_524030", "gene_names_uniprotkb": "CycA; 02; 05; 06; 07; 13; 16; 23; 24; 34; CG5940; CLD3; CYCA; CYCLIN A; Cyc A; CyclinA; DmcycA; Dmel\\CG5940; Dmel_CG5940; S(rux)3B; anon-WO0140519.128; cycA; cyclin A; dCycA; hari; l(3)03946; l(3)183; l(3)68Ea; l(3)j3C8; l(3)neo114; l(3)rsg11; rsg11", "gene_names_refseq": "0033/02; 0040/24; 0046/23; 0104/07; 0245/34; 0521/06; 0545/13; 1329/16; 1449/05; CG5940; CLD3; CYCA; CYCLIN A; Cyc A; CycA; CyclinA; DmcycA; Dmel\\CG5940; S(rux)3B; anon-WO0140519.128; cycA; cyclin A; dCycA; hari; l(3)03946; l(3)183; l(3)68Ea; l(3)j3C8; l(3)neo114; l(3)rsg11; rsg11", "protein_names_uniprotkb": "G2/mitotic-specific cyclin-A", "protein_names_refseq": "CG5940-PA; CycA-PA; cyclin A, isoform A; cyclin A; cyclin-A; cyclinA; rose-gespleten region interval 11; suppressor of rux 3B", "tax_id": 7227, "disease": "prostate cancer (Disease Ontology:DOID:10283); embryonal carcinoma (Disease Ontology:DOID:3308); myocardial infarction (Disease Ontology:DOID:5844); acute myeloid leukemia (Disease Ontology:DOID:9119)", "pathway": " (dme:Dmel_CG5940); (R-DME-1538133); (R-DME-174184); (R-DME-176408); (R-DME-187577); (R-DME-2559582); (R-DME-2559586); (R-DME-5689880); (R-DME-5693607); (R-DME-6804116); (R-DME-6804756); (R-DME-68911); (R-DME-68949); (R-DME-69017); (R-DME-69273); (R-DME-69478); (R-DME-69563); (R-DME-69656); (R-DME-75035)", "pathway_count": 19, "publication_count": 17, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;1332913;16110336;17431409;17569856;17569867;25589440;2564167;2564316;26109356;26109357;28484036", "class_list": "", "function": "Essential for the control of the cell cycle at the G2/M (mitosis) transition. Interacts with the Cdk1 and Cdk2 protein kinases to form MPF. G2/M cyclins accumulate steadily during G2 and are abruptly destroyed at mitosis., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 3, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q8IGR7;Q9VTP6;Q9VTP7", "ec_number_list": "", "go_molecular_function": "GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0045202 synapse;GO:0005815 microtubule organizing center", "go_biological_process": "GO:0000278 mitotic cell cycle;GO:0000082 G1/S transition of mitotic cell cycle;GO:0007096 regulation of exit from mitosis;GO:0007088 regulation of mitotic nuclear division;GO:2000738 positive regulation of stem cell differentiation", "synthesized_glycan_count": 0, "hit_score": 1.8, "record_id": "P14785-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P48451-1", "uniprot_id": "CANB1_DROME", "mass": 19341.0, "length": 170, "protein_name": "Calcineurin subunit B type 1", "gene_name": "CanB", "organism": "Fruit fly", "refseq_name": "calcineurin B, isoform B", "refseq_ac": "NP_001245531", "gene_names_uniprotkb": "CanB; BcDNA:RH11383; CANB1; CG4209; CNB1; CNB; CaNB; CaN; Can; CnB; Dmel\\CG4209; Dmel_CG4209; canB-4F; canB; dCnB1", "gene_names_refseq": "BcDNA:RH11383; CG4209; CNB; CaNB; CaN; CanB; Can; CnB; Dmel\\CG4209; canB-4F; canB; dCnB1", "protein_names_uniprotkb": "Calcineurin subunit B type 1; Protein phosphatase 2B regulatory subunit 1", "protein_names_refseq": "CG4209-PB; Calcineurin1; CanB-PB; calcineurin B, isoform B; calcineurin B", "tax_id": 7227, "disease": "traumatic brain injury (Disease Ontology:DOID:0081292); Alzheimer's disease (Disease Ontology:DOID:10652); dilated cardiomyopathy (Disease Ontology:DOID:12930); schizophrenia (Disease Ontology:DOID:5419)", "pathway": " (dme:Dmel_CG4209)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;1331060;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "Calcineurin is a calcium-binding and calmodulin-binding protein found in all cells from yeast to mammals, and a calcium-dependent, calmodulin-stimulated protein phosphatase., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9W4D0", "ec_number_list": "", "go_molecular_function": "GO:0005516 calmodulin binding;GO:0005509 calcium ion binding;GO:0019902 phosphatase binding;GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity", "go_cellular_component": "GO:0008021 synaptic vesicle;GO:0005955 calcineurin complex", "go_biological_process": "GO:0097720 calcineurin-mediated signaling;GO:0030431 sleep;GO:0016192 vesicle-mediated transport;GO:0007269 neurotransmitter secretion", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "P48451-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q24270-1", "uniprot_id": "CAC1D_DROME", "mass": 293753.0, "length": 2669, "protein_name": "Voltage-dependent calcium channel type D subunit alpha-1", "gene_name": "Ca-alpha1D", "organism": "Fruit fly", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Ca-alpha1D; A1D; BG:DS02795.1; CAD; CG4894; Ca-Alpha1D; Ca-_1D; Ca-a1D; Ca-alpha1; Ca-alphaID; Ca-alpha[[1]]D; Ca1D; Ca_alpha1D; Caalpha1D; D-type Ca[2+]; DmCa1D; DmCa1alpha1; Dmca1D; Dmel\\CG4894; Dmel_CG4894; DroCa1; alpha1D; alpha1; ca-alpha1D; ca-alpha1d; caID; cad; dmca1D; l(2)35Fa; l35Fa", "gene_names_refseq": "", "protein_names_uniprotkb": "Voltage-dependent calcium channel type D subunit alpha-1; DmCa1D", "protein_names_refseq": "", "tax_id": 7227, "disease": "congenital stationary night blindness (Disease Ontology:DOID:0050534); Aland Island eye disease (Disease Ontology:DOID:0050630); alcohol dependence (Disease Ontology:DOID:0050741); Timothy syndrome (Disease Ontology:DOID:0060173); neurodevelopmental disorder with hypotonia, language delay, and skeletal defects with or without seizures (Disease Ontology:DOID:0070536); congenital myopathy 18 (Disease Ontology:DOID:0081350); Brugada syndrome 3 (Disease Ontology:DOID:0110220); long QT syndrome 8 (Disease Ontology:DOID:0110649); congenital stationary night blindness 2A (Disease Ontology:DOID:0110871); X-linked cone-rod dystrophy 3 (Disease Ontology:DOID:0111007); sciatic neuropathy (Disease Ontology:DOID:11446); Duchenne muscular dystrophy (Disease Ontology:DOID:11723); hypokalemic periodic paralysis (Disease Ontology:DOID:14452); congenital heart disease (Disease Ontology:DOID:1682); schizophrenia (Disease Ontology:DOID:5419); malignant hyperthermia (Disease Ontology:DOID:8545); type 2 diabetes mellitus (Disease Ontology:DOID:9352)", "pathway": " (dme:Dmel_CG4894); (R-DME-422356); (R-DME-5576892); (R-DME-5576893)", "pathway_count": 4, "publication_count": 16, "publication_id_list": "10471707;10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357;7869089;9502794;9539432", "class_list": "", "function": "Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. Encodes a dihydropyridine- and diltiazem-sensitive current in larval body wall muscle. Vital for embryonic development., [UniProtKB, PubMed, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 4, "predicted_n_glycosites": 2, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 17, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "Q8IP23;Q8IP24;Q8IP25;Q95U73;Q9V3P7", "ec_number_list": "", "go_molecular_function": "GO:0046872 metal ion binding;GO:0005245 voltage-gated calcium channel activity;GO:0008331 high voltage-gated calcium channel activity", "go_cellular_component": "GO:0016323 basolateral plasma membrane;GO:0016324 apical plasma membrane;GO:0005891 voltage-gated calcium channel complex", "go_biological_process": "GO:0042045 epithelial fluid transport;GO:0006936 muscle contraction;GO:0016322 neuron remodeling;GO:0019722 calcium-mediated signaling;GO:0006816 calcium ion transport", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "Q24270-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q03019-1", "uniprot_id": "TWINE_DROME", "mass": 48320.0, "length": 426, "protein_name": "Cdc25-like protein phosphatase twine", "gene_name": "twe", "organism": "Fruit fly", "refseq_name": "twine, isoform B", "refseq_ac": "NP_001260491", "gene_names_uniprotkb": "twe; BG:DS02740.1; CG4965; Cdc25; Dmel\\CG4965; Dmel_CG4965; TWINE; Twe; cdc25; l(2)35Fh; mat(2)syn-A; mat(2)synHB5; mat(2)syn[HB5]; twn", "gene_names_refseq": "BG:DS02740.1; CG4965; Cdc25; Dmel\\CG4965; TWINE; Twe; cdc25; l(2)35Fh; mat(2)syn-A; mat(2)synHB5; mat(2)syn[HB5]; twe; twn", "protein_names_uniprotkb": "Cdc25-like protein phosphatase twine; 3.1.3.48", "protein_names_refseq": "CG4965-PB; twe-PB; twine, isoform B; twine", "tax_id": 7227, "disease": "endometrial hyperplasia (Disease Ontology:DOID:0080365); autosomal recessive polycystic kidney disease (Disease Ontology:DOID:0110861); prostate cancer (Disease Ontology:DOID:10283); urinary bladder cancer (Disease Ontology:DOID:11054); endometrial cancer (Disease Ontology:DOID:1380); vulva squamous cell carcinoma (Disease Ontology:DOID:2101); breast carcinoma (Disease Ontology:DOID:3459); cervical cancer (Disease Ontology:DOID:4362)", "pathway": " (dme:Dmel_CG4965); (R-DME-156711); (R-DME-176187); (R-DME-5625740); (R-DME-5689880); (R-DME-69200); (R-DME-69202); (R-DME-69273); (R-DME-69601); (R-DME-69656); (R-DME-75035)", "pathway_count": 11, "publication_count": 15, "publication_id_list": "10471707;10731132;12537568;12537569;12537572;12537573;12537574;1286615;1606618;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "Required during meiosis. Regulates the transition from the extended G2 phase to the onset of the first meiotic division., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 8, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9V454", "ec_number_list": "2.7.11.1;2.7.11.13;3.1.3.16;3.1.3.48;2.7.11.24;2.7.11.22;2.7.11.23;3.1.3.-;2.7.11.21;3.1.3.2;2.7.11.26;3.1.3.27;3.4.26.1;3.4.19.-;5.6.1.5;3.4.19.12", "go_molecular_function": "GO:0004725 protein tyrosine phosphatase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005819 spindle", "go_biological_process": "GO:0007283 spermatogenesis;GO:0010971 positive regulation of G2/M transition of mitotic cell cycle;GO:0051301 cell division;GO:0000086 G2/M transition of mitotic cell cycle;GO:0007140 male meiotic nuclear division", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "Q03019-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q6WV16-1", "uniprot_id": "GALT6_DROME", "mass": 76972.0, "length": 666, "protein_name": "N-acetylgalactosaminyltransferase 6", "gene_name": "Pgant6", "organism": "Fruit fly", "refseq_name": "polypeptide N-Acetylgalactosaminyltransferase 6, isoform C", "refseq_ac": "NP_001261342", "gene_names_uniprotkb": "Pgant6; CG2103; Dmel\\CG2103; Dmel_CG2103; pgant6", "gene_names_refseq": "CG2103; Dmel\\CG2103; Pgant6; pgant6", "protein_names_uniprotkb": "N-acetylgalactosaminyltransferase 6; 2.4.1.41; Protein-UDP acetylgalactosaminyltransferase 6; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 6; pp-GaNTase 6", "protein_names_refseq": "CG2103-PC; Pgant6-PC; polypeptide GalNAc transferase 6; polypeptide N-Acetylgalactosaminyltransferase 6, isoform C", "tax_id": 7227, "disease": "depressive disorder (Disease Ontology:DOID:1596)", "pathway": " (dme:Dmel_CG2103); (R-DME-913709)", "pathway_count": 2, "publication_count": 16, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;12829714;16110336;16251381;17569856;17569867;20807760;22157008;25589440;26109356;26109357", "class_list": "", "function": "Glycopeptide transferase involved in O-linked oligosaccharide biosynthesis, which catalyzes the transfer of an N-acetyl-D-galactosamine residue to an already glycosylated peptide (PubMed:12829714). In contrast to other proteins of the family, it does not act as a peptide transferase that transfers GalNAc onto serine or threonine residue on the protein receptor, but instead requires the prior addition of a GalNAc on a peptide before adding additional GalNAc moieties (PubMed:12829714). Some peptide transferase activity is however not excluded, considering that its appropriate peptide substrate may remain unidentified (PubMed:12829714). Prefers the diglycosylated Muc5AC-3/13 as substrate (PubMed:12829714). Might have a role in protein O-glycosylation in the Golgi and thereby in establishing and/or maintaining a proper secretory apparatus structure (PubMed:20807760)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 4, "predicted_n_glycosites": 4, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "Q0E8I9;Q95R40;Q9VZX5", "ec_number_list": "2.4.1.-;2.4.1.41", "go_molecular_function": "GO:0046872 metal ion binding;GO:0030246 carbohydrate binding;GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0005795 Golgi stack", "go_biological_process": "GO:0006493 protein O-linked glycosylation;GO:0016266 protein O-linked glycosylation via N-acetyl-galactosamine", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "Q6WV16-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P48603-1", "uniprot_id": "CAPZB_DROME", "mass": 31363.0, "length": 276, "protein_name": "F-actin-capping protein subunit beta", "gene_name": "cpb", "organism": "Fruit fly", "refseq_name": "capping protein beta, isoform B", "refseq_ac": "NP_001259877", "gene_names_uniprotkb": "cpb; ANCP-BETA; CAPB_DROME; CG17158; CP-beta; CPB; CP; Cap2; CapZbeta; CapZ; CpB; Cpbeta; Cpb; Dmel\\CG17158; Dmel_CG17158; J; bnd; cpbeta", "gene_names_refseq": "CAPB_DROME; CG17158; CP-beta; CPB; CP; Cap2; CapZbeta; CapZ; CpB; Cpbeta; Cpb; Dmel\\CG17158; J; bnd; cpbeta; cpb", "protein_names_uniprotkb": "F-actin-capping protein subunit beta", "protein_names_refseq": "CG17158-PB; CP beta subunit; Capping-protein-beta; F-actin capping protein; actin capping protein beta; actin-capping protein; ancpbeta; burned; capping protein beta, isoform B; capping proteinbeta; capping proteins beta; cpb-PB", "tax_id": 7227, "disease": "dementia (Disease Ontology:DOID:1307); cleft palate (Disease Ontology:DOID:674)", "pathway": " (dme:Dmel_CG17158)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357;8682865", "class_list": "", "function": "F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments., [UniProtKB, UniProtKB, UniProtKB, PubMed, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9VQ33", "ec_number_list": "", "go_molecular_function": "GO:0046982 protein heterodimerization activity;GO:0051015 actin filament binding;GO:0003779 actin binding", "go_cellular_component": "GO:0015629 actin cytoskeleton;GO:0008290 F-actin capping protein complex;GO:0005869 dynactin complex;GO:0071203 WASH complex;GO:0005737 cytoplasm", "go_biological_process": "GO:0030832 regulation of actin filament length;GO:0007015 actin filament organization;GO:0000902 cell morphogenesis;GO:0030036 actin cytoskeleton organization;GO:0051016 barbed-end actin filament capping", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "P48603-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q27268-1", "uniprot_id": "DX39B_DROME", "mass": 48652.0, "length": 424, "protein_name": "ATP-dependent RNA helicase WM6", "gene_name": "Hel25E", "organism": "Fruit fly", "refseq_name": "helicase at 25E, isoform A", "refseq_ac": "NP_723089", "gene_names_uniprotkb": "Hel25E; CG7269; Dbp25F; DmRH4; Dmel\\CG7269; Dmel_CG7269; HEL25E; HEL; Hel; UAP56; Uap56; WM6; Wm6; dHel25E; hel25E; hel; jf26; l(2)25Eb; l(2)gdh-12; l(2)gdh12; l(2)jf26; l(2)k11511; sz; uap56", "gene_names_refseq": "CG7269; Dbp25F; DmRH4; Dmel\\CG7269; HEL25E; HEL; Hel25E; Hel; UAP56; Uap56; WM6; Wm6; dHel25E; hel25E; hel; jf26; l(2)25Eb; l(2)gdh-12; l(2)gdh12; l(2)jf26; l(2)k11511; sz; uap56", "protein_names_uniprotkb": "ATP-dependent RNA helicase WM6; 3.6.4.13; DEAD box protein UAP56; Dmrnahel; HEL/UAP56", "protein_names_refseq": "CG7269-PA; Hel25E-PA; RNA helicase; helicase at 25E, isoform A; lethal(2)25Eb", "tax_id": 7227, "disease": "type 1 diabetes mellitus (Disease Ontology:DOID:9744)", "pathway": " (dme:Dmel_CG7269); (R-DME-159236); (R-DME-72163); (R-DME-9013418)", "pathway_count": 4, "publication_count": 16, "publication_id_list": "10731132;11696332;12537568;12537569;12537572;12537573;12537574;12743041;16110336;17569856;17569867;25589440;26109356;26109357;7808417;9215899", "class_list": "", "function": "Required for mRNA export out of the nucleus. Probable RNA helicase that may regulate entry into mitosis by down-regulating the expression of other genes whose activity may be rate-limiting for entry into mitosis during embryogenesis. Binds to salivary gland chromosomes and modifies position effect variegation. Promotes an open chromatin structure that favors transcription during development by regulating the spread of heterochromatin., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q540X0;Q9VMQ1", "ec_number_list": "3.6.4.13;7.2.2.-;3.6.4.-;2.7.7.6;3.6.4.10;3.6.4.6;3.6.4.12;5.6.2.4;5.6.2.5;2.7.4.3;5.6.2.3;3.1.-.-;2.7.11.1;3.6.1.15;5.2.1.8;3.-.-.-;5.6.1.1;3.6.-.-;5.6.2.-", "go_molecular_function": "GO:0003729 mRNA binding;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0034584 piRNA binding;GO:0003724 RNA helicase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0016607 nuclear speck;GO:0005681 spliceosomal complex;GO:0000346 transcription export complex;GO:0043186 P granule", "go_biological_process": "GO:0006338 chromatin remodeling;GO:0006406 mRNA export from nucleus;GO:0000398 mRNA splicing, via spliceosome;GO:0034587 piRNA processing;GO:0000381 regulation of alternative mRNA splicing, via spliceosome", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "Q27268-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q960N3-1", "uniprot_id": "CORT_DROME", "mass": 55575.0, "length": 483, "protein_name": "Protein cortex", "gene_name": "cort", "organism": "Fruit fly", "refseq_name": "cortex, isoform B", "refseq_ac": "NP_001260144", "gene_names_uniprotkb": "cort; CG11330; Cort; Dmel\\CG11330; Dmel_CG11330; cor", "gene_names_refseq": "CG11330; Cort; Dmel\\CG11330; cort; cor", "protein_names_uniprotkb": "Protein cortex", "protein_names_refseq": "CG11330-PB; cdc20-like; cort-PB; cortex, isoform B; cortex", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG11330)", "pathway_count": 1, "publication_count": 18, "publication_id_list": "10683177;10731132;10924478;11252055;12537568;12537569;12537572;12537573;12537574;16110336;17251266;17569856;17569867;18020708;24019759;25589440;26109356;26109357", "class_list": "", "function": "Female meiosis-specific activator of the anaphase promoting complex/cyclosome (APC/C) (PubMed:17251266, PubMed:18020708). Required for the completion of meiosis in oocytes (PubMed:10683177, PubMed:10924478, PubMed:11252055, PubMed:17251266, PubMed:18020708). Activates the ubiquitin ligase activity and substrate specificity of APC/C and triggers the sequential degradation of mitotic cyclins in meiosis (PubMed:17251266, PubMed:18020708). Promotes the ubiquitination and degradation of CycA early in meiosis I and the degradation of CycB and CycB3 after egg activation (PubMed:18020708). Promotes degradation of mtrm at the oocyte-to-embryo transition (PubMed:24019759)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 3, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9VMA1", "ec_number_list": "", "go_molecular_function": "GO:0010997 anaphase-promoting complex binding;GO:1990757 ubiquitin ligase activator activity;GO:0097027 ubiquitin-protein transferase activator activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005680 anaphase-promoting complex", "go_biological_process": "GO:0007147 female meiosis II;GO:0045143 homologous chromosome segregation;GO:0007144 female meiosis I;GO:0007143 female meiotic nuclear division;GO:0031145 anaphase-promoting complex-dependent catabolic process", "synthesized_glycan_count": 0, "hit_score": 1.9, "record_id": "Q960N3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q24180-1", "uniprot_id": "DEAF1_DROME", "mass": 61598.0, "length": 576, "protein_name": "Deformed epidermal autoregulatory factor 1", "gene_name": "Deaf1", "organism": "Fruit fly", "refseq_name": "deformed epidermal autoregulatory factor-1, isoform D", "refseq_ac": "NP_001262069", "gene_names_uniprotkb": "Deaf1; CG8567; DEAF-1; DEAF1; Deaf-1; Dmel\\CG8567; Dmel_CG8567; deaf1; l(3)76BDv", "gene_names_refseq": "CG8567; DEAF-1; DEAF1; Deaf-1; Deaf1; Dmel\\CG8567; deaf1; l(3)76BDv", "protein_names_uniprotkb": "Deformed epidermal autoregulatory factor 1; Protein DEAF-1", "protein_names_refseq": "CG8567-PD; Deaf1-PD; deaf-1; deformed epidermal autoregulatory factor-1, isoform D; deformed epidermal autoregulatory factor-1", "tax_id": 7227, "disease": "Vulto-van Silfout-de Vries syndrome (Disease Ontology:DOID:0070054)", "pathway": " (dme:Dmel_CG8567)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357;8617243", "class_list": "", "function": "Transcription factor that binds the homeotic Deformed (Dfd) response element. High affinity binding sites contain at least 1 TTCG motif surrounded by additional TCG sequences. May be involved in the selective action of Dfd on these sites without binding directly to the Dfd protein. Requirement of DEAF1 activity may be a common feature of enhancers targeted by Dfd., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0008270 zinc ion binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0043565 sequence-specific DNA binding;GO:0003677 DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005700 polytene chromosome", "go_biological_process": "GO:0009792 embryo development ending in birth or egg hatching;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0050776 regulation of immune response;GO:0045893 positive regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "Q24180-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P35554-1", "uniprot_id": "FTN_DROME", "mass": 20656.0, "length": 182, "protein_name": "Flightin", "gene_name": "fln", "organism": "Fruit fly", "refseq_name": "flightin, isoform B", "refseq_ac": "NP_001262084", "gene_names_uniprotkb": "fln; CG7445; Dmel\\CG7445; Dmel_CG7445; FTN; Fln; Ftn; mp27", "gene_names_refseq": "CG7445; Dmel\\CG7445; Fln; Ftn; fln; mp27", "protein_names_uniprotkb": "Flightin; Muscle protein 27", "protein_names_refseq": "CG7445-PB; flightin, isoform B; flightin; fln-PB", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG7445)", "pathway_count": 1, "publication_count": 14, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;17912596;25589440;26109356;26109357;8486738", "class_list": "", "function": "Possibly involved in the regulation of flight muscles contraction, possibly by modulating actin-myosin interaction., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9VW65", "ec_number_list": "", "go_molecular_function": "GO:0008307 structural constituent of muscle;GO:0097493 structural molecule activity conferring elasticity", "go_cellular_component": "GO:0031672 A band;GO:0005863 striated muscle myosin thick filament", "go_biological_process": "GO:0071688 striated muscle myosin thick filament assembly;GO:0045214 sarcomere organization;GO:0007527 adult somatic muscle development;GO:0014703 oscillatory muscle contraction", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "P35554-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P19967-1", "uniprot_id": "CYB5R_DROME", "mass": 50355.0, "length": 436, "protein_name": "Cytochrome b5-related protein", "gene_name": "Cyt-b5-r", "organism": "Fruit fly", "refseq_name": "cytochrome b5-related, isoform B", "refseq_ac": "NP_001260514", "gene_names_uniprotkb": "Cyt-b5-r; CG13279; Cyt-b5; Cyt-b; Cytb5r; Cytb5; Cytb; Dmel\\CG13279; Dmel_CG13279; TU-36B; TU36B", "gene_names_refseq": "CG13279; Cyt-b5-r; Cyt-b5; Cyt-b; Cytb5r; Cytb5; Cytb; Dmel\\CG13279; TU-36B; TU36B", "protein_names_uniprotkb": "Cytochrome b5-related protein; Protein TU-36B", "protein_names_refseq": "CG13279-PB; Cyt-b5-r-PB; cytochrome b5-related, isoform B", "tax_id": 7227, "disease": "discrete subaortic stenosis (Disease Ontology:DOID:5804); congestive heart failure (Disease Ontology:DOID:6000); type 1 diabetes mellitus (Disease Ontology:DOID:9744)", "pathway": " (dme:Dmel_CG13279)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;2549511;25589440;26109356;26109357", "class_list": "", "function": "May play a role in muscle cell metabolism., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9VJI2", "ec_number_list": "", "go_molecular_function": "GO:0046872 metal ion binding;GO:0020037 heme binding;GO:0062076 acyl-CoA (8-3)-desaturase activity;GO:0016491 oxidoreductase activity", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0006629 lipid metabolic process", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "P19967-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q6NP60-1", "uniprot_id": "MOX12_DROME", "mass": 84741.0, "length": 760, "protein_name": "MOXD1 homolog 2", "gene_name": "olf413", "organism": "Fruit fly", "refseq_name": "olf413, isoform C", "refseq_ac": "NP_001262204", "gene_names_uniprotkb": "olf413; CG12673; CG14461; CG7495; CR33185; Dmel\\CG12673; Dmel_CG12673; Olf413", "gene_names_refseq": "CG12673; CG14461; CG7495; CR33185; Dmel\\CG12673; Olf413; olf413", "protein_names_uniprotkb": "MOXD1 homolog 2", "protein_names_refseq": "CG12673-PC; olf413, isoform C; olf413-PC", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG12673)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 4, "predicted_n_glycosites": 4, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "Q9GTU8;Q9VNV6", "ec_number_list": "", "go_molecular_function": "GO:0005507 copper ion binding;GO:0004500 dopamine beta-monooxygenase activity;GO:0004836 tyramine-beta hydroxylase activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0030667 secretory granule membrane", "go_biological_process": "GO:0042420 dopamine catabolic process;GO:0006589 octopamine biosynthetic process;GO:0042421 norepinephrine biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "Q6NP60-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9V3D5-1", "uniprot_id": "DYRK2_DROME", "mass": 79609.0, "length": 722, "protein_name": "Dual specificity tyrosine-phosphorylation-regulated kinase 2", "gene_name": "Dyrk2", "organism": "Fruit fly", "refseq_name": "Dual-specificity tyrosine phosphorylation-regulated kinase 2, isoform D", "refseq_ac": "NP_001033906", "gene_names_uniprotkb": "Dyrk2; BG:DS01523.3; CG4551; DYRK2; DYRK; Dm2; DmDyrk2; Dmel\\CG4551; Dmel_CG4551; dDYRK2; smi35A", "gene_names_refseq": "BG:DS01523.3; CG4551; DYRK2; DYRK; Dm2; DmDyrk2; Dmel\\CG4551; Dyrk2; dDYRK2; smi35A", "protein_names_uniprotkb": "Dual specificity tyrosine-phosphorylation-regulated kinase 2; 2.7.12.1; Protein smell impaired at 35A; dDyrk2", "protein_names_refseq": "CG4551-PD; Dual-specificity tyrosine phosphorylation-regulated kinase 2, isoform D; Dyrk2-PD; dual specificity tyrosine phosphorylation-regulated kinase; smell impaired 35A", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG4551)", "pathway_count": 1, "publication_count": 15, "publication_id_list": "10471707;10731132;12537568;12537569;12537572;12537573;12537574;12786602;16110336;17569856;17569867;18327897;25589440;26109356;26109357", "class_list": "", "function": "In vitro; can phosphorylate exogenous substrates on Ser and Thr residues. May have a physiological role in development being involved in cellular growth and differentiation., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 4, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A4V0P7;Q8T0L9", "ec_number_list": "2.7.11.17;2.7.11.1;2.7.11.13;2.7.11.24;2.7.10.1;2.7.11.22;2.7.11.21;2.7.10.2;5.6.1.8;2.7.11.11;2.7.11.23;2.7.12.1;2.7.11.25;2.7.11.12;2.7.12.2;2.7.11.39", "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0004713 protein tyrosine kinase activity;GO:0005524 ATP binding;GO:0004712 protein serine/threonine/tyrosine kinase activity;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005856 cytoskeleton", "go_biological_process": "GO:0042048 olfactory behavior;GO:0007608 sensory perception of smell;GO:0009416 response to light stimulus;GO:0030177 positive regulation of Wnt signaling pathway", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "Q9V3D5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P49858-1", "uniprot_id": "CNI_DROME", "mass": 16931.0, "length": 144, "protein_name": "Protein cornichon", "gene_name": "cni", "organism": "Fruit fly", "refseq_name": "cornichon, isoform C", "refseq_ac": "NP_001260495", "gene_names_uniprotkb": "cni; BG:DS02740.13; CG5855; Cni; Dmel\\CG5855; Dmel_CG5855; IV; anon-35Fe; spnG", "gene_names_refseq": "BG:DS02740.13; CG5855; Cni; Dmel\\CG5855; IV; anon-35Fe; cni; spnG", "protein_names_uniprotkb": "Protein cornichon", "protein_names_refseq": "CG5855-PC; cni-PC; cornichon, isoform C; cornichon; spindle-G", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG5855); (R-DME-204005); (R-DME-5694530)", "pathway_count": 3, "publication_count": 14, "publication_id_list": "10471707;10731132;12537568;12537572;12537573;12537574;16110336;16396907;17569856;17569867;25589440;26109356;26109357;7540118", "class_list": "", "function": "Acts as a cargo receptor necessary for the transportation of gurken (grk) to a transitional endoplasmic reticulum (tER) site and promotes its incorporation into coat protein complex II (COPII) vesicles. Associated with gurken, produces a signal received by torpedo resulting in a signaling pathway that first establishes posterior follicle cell fates and normal localization of the anterior and posterior determinants, later they act in a signaling event inducing dorsal follicle cell fates and regulating the dorsal-ventral pattern of egg and embryo., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A4V0S2;Q53XF2;Q9V423", "ec_number_list": "", "go_molecular_function": "GO:0005102 signaling receptor binding", "go_cellular_component": "GO:0030134 COPII-coated ER to Golgi transport vesicle;GO:0005789 endoplasmic reticulum membrane;GO:0016020 membrane", "go_biological_process": "GO:0015031 protein transport;GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0009952 anterior/posterior pattern specification;GO:0016192 vesicle-mediated transport;GO:0007310 oocyte dorsal/ventral axis specification", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "P49858-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q8IRC7-1", "uniprot_id": "AWH_DROME", "mass": 31032.0, "length": 275, "protein_name": "LIM/homeobox protein Awh", "gene_name": "Awh", "organism": "Fruit fly", "refseq_name": "arrowhead, isoform A", "refseq_ac": "NP_523907", "gene_names_uniprotkb": "Awh; Awh; CG1072; Dmel\\CG1072; Dmel_CG1072; awh; l(3)63Ea; l(3)64Ea; l(3)SH9; l63Ea", "gene_names_refseq": "Awh; CG1072; Dmel\\CG1072; awh; l(3)63Ea/Awh; l(3)63Ea; l(3)64Ea; l(3)SH9; l63Ea", "protein_names_uniprotkb": "LIM/homeobox protein Awh; Protein arrowhead", "protein_names_refseq": "Awh-PA; CG1072-PA; arrowhead, isoform A; arrowhead; lethal(3)63Ea", "tax_id": 7227, "disease": "depressive disorder (Disease Ontology:DOID:1596)", "pathway": " (dme:Dmel_CG1072)", "pathway_count": 1, "publication_count": 15, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;18327897;20040493;25589440;26109356;26109357;9331336", "class_list": "", "function": "Probable transcription factor (Probable). Required for the establishment of a subset of imaginal tissues: the abdominal histoblasts and the salivary gland imaginal rings (PubMed:9331336). Together with Chi/chip regulates eye differentiation at the ventral eye-antennal boundary (PubMed:20040493)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 3, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "O18547;Q1LYZ6;Q8SZ10;Q9VZM0", "ec_number_list": "", "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0046872 metal ion binding;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677 DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0048749 compound eye development;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0006355 regulation of DNA-templated transcription;GO:0030182 neuron differentiation", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "Q8IRC7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q09024-1", "uniprot_id": "IMPL2_DROME", "mass": 29895.0, "length": 267, "protein_name": "Neural/ectodermal development factor IMP-L2", "gene_name": "ImpL2", "organism": "Fruit fly", "refseq_name": "Ecdysone-inducible gene L2, isoform D", "refseq_ac": "NP_001261409", "gene_names_uniprotkb": "ImpL2; CG15009; CG46460; CT34862; Dmel\\CG15009; Dmel\\CG46460; Dmel_CG15009; Dmel_CG46460; GH28; IMP-L2; IMPL2; Imp-12; Imp-L2; ImpL-2; Impl2; imp-L2; impL2; impl2", "gene_names_refseq": "CG15009; CT34862; Dmel\\CG15009; GH28; IMP-L2; IMPL2; Imp-12; Imp-L2; ImpL-2; ImpL2; Impl2; imp-L2; impL2; impl2", "protein_names_uniprotkb": "Neural/ectodermal development factor IMP-L2", "protein_names_refseq": "CG15009-PD; Ecdysone-inducible gene L2, isoform D; ImpL2-PD; ecdysone-inducible gene L2; imaginal morphogenesis protein-late 2; neural and ectodermal development factor", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG15009); (R-DME-1474228); (R-DME-210991); (R-DME-216083); (R-DME-428542); (R-DME-433692); (R-DME-9749641)", "pathway_count": 7, "publication_count": 13, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357;8306886", "class_list": "", "function": "Essential developmental role during embryogenesis, in particular the normal development of the nervous system. May be involved in some aspect of cell adhesion., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q6NLN1;Q7KV52;Q95SU7;Q9VZF7", "ec_number_list": "", "go_molecular_function": "GO:0098632 cell-cell adhesion mediator activity;GO:0043559 insulin binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005886 plasma membrane;GO:0030424 axon;GO:0005576 extracellular region", "go_biological_process": "GO:0046627 negative regulation of insulin receptor signaling pathway;GO:0010888 negative regulation of lipid storage;GO:0042594 response to starvation;GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules;GO:0046628 positive regulation of insulin receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "Q09024-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P55965-1", "uniprot_id": "BYN_DROME", "mass": 72117.0, "length": 697, "protein_name": "T-related protein", "gene_name": "byn", "organism": "Fruit fly", "refseq_name": "brachyenteron, isoform B", "refseq_ac": "NP_524031", "gene_names_uniprotkb": "byn; Bra; Byn; CG7260; D-TRA; D-Trg; DTrg; Dm-BYN; Dmel\\CG7260; Dmel_CG7260; Tra; Trg; apro; dm-Trg; trg", "gene_names_refseq": "Bra; Byn; CG7260; D-TRA; D-Trg; DTrg; Dm-BYN; Dmel\\CG7260; Tra; Trg; apro; byn/apro; byn; dm-Trg; trg", "protein_names_uniprotkb": "T-related protein; Protein brachyenteron; Trp", "protein_names_refseq": "CG7260-PB; T related antigen; T-related gene; aproctous; brachyenteron, isoform B; brachyenteron; brachyury; byn-PB", "tax_id": 7227, "disease": "alcohol dependence (Disease Ontology:DOID:0050741); neural tube defect (Disease Ontology:DOID:0080074); adrenocorticotropic hormone deficiency (Disease Ontology:DOID:0080150); inherited metabolic disorder (Disease Ontology:DOID:655)", "pathway": " (dme:Dmel_CG7260)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357;7958884", "class_list": "", "function": "Required for the specification of the hindgut and anal pads., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q9VTQ7", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0042803 protein homodimerization activity;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003700 DNA-binding transcription factor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0000785 chromatin", "go_biological_process": "GO:0001708 cell fate specification;GO:0007442 hindgut morphogenesis;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0045944 positive regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "P55965-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P48423-1", "uniprot_id": "GAP1_DROME", "mass": 132087.0, "length": 1163, "protein_name": "GTPase-activating protein", "gene_name": "RasGAP1", "organism": "Fruit fly", "refseq_name": "Ras GTPase activating protein 1, isoform A", "refseq_ac": "NP_524014", "gene_names_uniprotkb": "RasGAP1; CG6721; Dmel\\CG6721; Dmel_CG6721; FBpp0076097; GAP1; GAP; Gap 1; Gap1; Gap; Ras-GAP; RasGAP; RasGap1; gap1; gap; mip; rI533; rasGAP; sxt", "gene_names_refseq": "CG6721; Dmel\\CG6721; FBpp0076097; GAP1; GAP; Gap 1; Gap1; Gap; Ras-GAP; RasGAP1; RasGAP; RasGap1; gap1; gap; mip; rI533; rasGAP; sxt", "protein_names_uniprotkb": "GTPase-activating protein; Ras GTPase-activating protein 1", "protein_names_refseq": "CG6721-PA; GTPase activating protein 1; GTPase activating protein1; GTPase-activating protein 1; Ras GTPase activating protein 1, isoform A; RasGAP1-PA; more inner photoreceptors; seven extra; sextra", "tax_id": 7227, "disease": "aplastic anemia (Disease Ontology:DOID:12449); Noonan syndrome (Disease Ontology:DOID:3490)", "pathway": " (dme:Dmel_CG6721); (R-DME-5658442)", "pathway_count": 2, "publication_count": 14, "publication_id_list": "10089881;10731132;12537568;12537569;12537572;12537573;12537574;1547500;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "Inhibitory regulator of the Ras-cyclic AMP pathway. May function as a negative regulator of Ras85D/Ras1 in the sev signaling pathway. Acts cell autonomously in cone cell precursors as a negative regulator of R7 photoreceptor cell determination., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A4V1S6;Q6NP17;Q9VT58", "ec_number_list": "", "go_molecular_function": "GO:0005096 GTPase activator activity;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0035556 intracellular signal transduction;GO:1902531 regulation of intracellular signal transduction;GO:0045792 negative regulation of cell size;GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway;GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "P48423-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q94899-1", "uniprot_id": "CSN2_DROME", "mass": 51527.0, "length": 444, "protein_name": "COP9 signalosome complex subunit 2", "gene_name": "alien", "organism": "Fruit fly", "refseq_name": "alien, isoform D", "refseq_ac": "NP_001260276", "gene_names_uniprotkb": "alien; Alien; BcDNA:LD10463; CG9556; CH2; CSN2; Csn2; DCH2; Dch2; Dmel\\CG9556; Dmel_CG9556; csn2", "gene_names_refseq": "Alien; BcDNA:LD10463; CG9556; CH2; CSN2; Csn2; DCH2; Dch2; Dmel\\CG9556; alien; csn2", "protein_names_uniprotkb": "COP9 signalosome complex subunit 2; Alien protein; Dch2; Signalosome subunit 2", "protein_names_refseq": "CG9556-PD; COP9 complex homolog subunit 2; alien, isoform D; alien-PD; d-Alien; drosophila COP9 signalosome homolog 2", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG9556); (R-DME-5696394); (R-DME-6781823); (R-DME-8856825); (R-DME-8951664); (R-DME-9013422)", "pathway_count": 6, "publication_count": 16, "publication_id_list": "10531038;10731132;12426099;12537568;12537569;12537572;12537573;12537574;12737805;16110336;17569856;17569867;25589440;26109356;26109357;8817453", "class_list": "", "function": "Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of the SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF. The CSN complex plays an essential role in oogenesis and embryogenesis and is required for proper photoreceptor R cell differentiation and promote lamina glial cell migration or axon targeting. It also promotes Ubl-dependent degradation of cyclin E (CycE) during early oogenesis., [UniProtKB, PubMed, UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A4V0G9;Q8MSX8;Q9V3Z0", "ec_number_list": "", "go_molecular_function": "GO:0003714 transcription corepressor activity;GO:0016922 nuclear receptor binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0008180 COP9 signalosome;GO:0008231 repressor ecdysone receptor complex", "go_biological_process": "GO:0045892 negative regulation of DNA-templated transcription;GO:0050821 protein stabilization;GO:0007281 germ cell development;GO:0000338 protein deneddylation;GO:0048140 male germ-line cyst encapsulation", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "Q94899-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q04691-1", "uniprot_id": "FBP1_DROME", "mass": 119663.0, "length": 1029, "protein_name": "Fat-body protein 1", "gene_name": "Fbp1", "organism": "Fruit fly", "refseq_name": "Fat body protein 1, isoform A", "refseq_ac": "NP_524065", "gene_names_uniprotkb": "Fbp1; CG17285; DmeFBP1; Dmel\\CG17285; Dmel_CG17285; FBP-1; FBP1; FbP1; Fbp-1; LP07910p; P1; fbp-1; fbp1", "gene_names_refseq": "CG17285; DmeFBP1; Dmel\\CG17285; FBP-1; FBP1; FbP1; Fbp-1; Fbp1; LP07910p; P1; fbp-1; fbp1", "protein_names_uniprotkb": "Fat-body protein 1; P1 protein", "protein_names_refseq": "1; CG17285-PA; Fat body protein 1, isoform A; Fat body protein; Fbp1-PA; Protein-1; fat body protein 1; fat body protein-1; fat body protein1", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG17285)", "pathway_count": 1, "publication_count": 14, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;1696317;17569856;17569867;25589440;26109356;26109357;8293980", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q86PB6;Q8IQL4;Q9VUD0", "ec_number_list": "", "go_molecular_function": "GO:0045735 nutrient reservoir activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0097009 energy homeostasis", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "Q04691-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q24533-1", "uniprot_id": "DICH_DROME", "mass": 40212.0, "length": 382, "protein_name": "SOX domain-containing protein dichaete", "gene_name": "D", "organism": "Fruit fly", "refseq_name": "dichaete, isoform B", "refseq_ac": "NP_001261830", "gene_names_uniprotkb": "D; CG5893; DM10; DM23; DM33; DM36; DM63; Dic; Dmel\\CG5893; Dmel_CG5893; SOX70D; SOX70; SOXB2.1; SOXDP; Sox B2-1; Sox70D; Sox70; Sry-rDM10; Sry-rDM23; Sry-rDM33; Sry-rDM36; Sry-rDM63; d; fish; l(3)LG9; loD", "gene_names_refseq": "CG5893; DM10; DM23; DM33; DM36; DM63; Dic; Dmel\\CG5893; D; SOX70D; SOX70; SOXB2.1; SOXDP; Sox B2-1; Sox70D; Sox70; Sry-rDM10; Sry-rDM23; Sry-rDM33; Sry-rDM36; Sry-rDM63; d; fish; l(3)LG9; loD", "protein_names_uniprotkb": "SOX domain-containing protein dichaete; Protein fish-hook", "protein_names_refseq": "CG5893-PB; D-PB; Fish-Hook; Sox box protein 70D; Sry-related DM10; Sry-related DM23; Sry-related DM33; Sry-related DM36; Sry-related DM63; dichaete, isoform B; dichaete; dicheate; fish hook; lethal of dichaete", "tax_id": 7227, "disease": "tongue squamous cell carcinoma (Disease Ontology:DOID:0050865); oral squamous cell carcinoma (Disease Ontology:DOID:0050866); traumatic brain injury (Disease Ontology:DOID:0081292); X-linked panhypopituitarism (Disease Ontology:DOID:0111779); syndromic microphthalmia 3 (Disease Ontology:DOID:0111801); nasal cavity cancer (Disease Ontology:DOID:10811); hydrocephalus (Disease Ontology:DOID:10908); lesion of sciatic nerve (Disease Ontology:DOID:12528); alcohol use disorder (Disease Ontology:DOID:1574); breast cancer (Disease Ontology:DOID:1612); squamous cell carcinoma (Disease Ontology:DOID:1749); melanoma (Disease Ontology:DOID:1909); transient cerebral ischemia (Disease Ontology:DOID:224); multiple sclerosis (Disease Ontology:DOID:2377); transitional cell carcinoma (Disease Ontology:DOID:2671); cholangiocarcinoma (Disease Ontology:DOID:4947); congestive heart failure (Disease Ontology:DOID:6000); retinal degeneration (Disease Ontology:DOID:8466); oral cavity cancer (Disease Ontology:DOID:8618)", "pathway": " (dme:Dmel_CG5893); (R-DME-3769402)", "pathway_count": 2, "publication_count": 13, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357;8951062;8951082", "class_list": "", "function": "Essential for segmentation and CNS development. May modulate the actions of other transcription factors, including gap and pair-rule proteins., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 19, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A2VED6;Q8MSP8;Q9VUD4", "ec_number_list": "", "go_molecular_function": "GO:0008301 DNA binding, bending;GO:0003677 DNA binding;GO:0003700 DNA-binding transcription factor activity;GO:0042802 identical protein binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0007442 hindgut morphogenesis;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006357 regulation of transcription by RNA polymerase II;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0006355 regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "Q24533-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q8ITC7-1", "uniprot_id": "CAPAR_DROME", "mass": 54005.0, "length": 477, "protein_name": "Neuropeptides capa receptor", "gene_name": "CapaR", "organism": "Fruit fly", "refseq_name": "capability receptor, isoform B", "refseq_ac": "NP_996140", "gene_names_uniprotkb": "CapaR; CAP2B-R; CAPA-R; CG14575; Capa R; Dm CG14575; Dmel\\CG14575; Dmel_CG14575; PVKr; capaR", "gene_names_refseq": "CAP2B-R; CAPA-R; CG14575; Capa R; CapaR; Dm CG14575; Dmel\\CG14575; PVKr; capaR", "protein_names_uniprotkb": "Neuropeptides capa receptor; Cap2b receptor; Capability receptor", "protein_names_refseq": "CAPA receptor; CG14575-PB; CapaR-PB; capa peptide receptor; capability receptor, isoform B", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG14575)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "10731132;12177421;12459185;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "Acts as a receptor for the neuropeptides CAP-1 and CAP-2, but not CAP-3. Probably a component of signal transduction pathway that leads to Malpighian tubule fluid secretion in response to these ligands., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "Q9VP15", "ec_number_list": "", "go_molecular_function": "GO:0008188 neuropeptide receptor activity;GO:0001607 neuromedin U receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane;GO:0016323 basolateral plasma membrane", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway;GO:0007218 neuropeptide signaling pathway;GO:0007589 body fluid secretion;GO:0051928 positive regulation of calcium ion transport;GO:0071465 cellular response to desiccation", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "Q8ITC7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q03751-1", "uniprot_id": "DNJC5_DROME", "mass": 26897.0, "length": 249, "protein_name": "DnaJ homolog subfamily C member 5 homolog", "gene_name": "Csp", "organism": "Fruit fly", "refseq_name": "cysteine string protein, isoform F", "refseq_ac": "NP_001287144", "gene_names_uniprotkb": "Csp; CG6395; CSP32; CSP; Cys; D-CSP; D.M.CSP; DCSP-1; DNAJC5; Dcsp; Dmel\\CG6395; Dmel_CG6395; MAB ab49; ab49; anon-WO02059370.50; csp29; csp32; csp; dCSP-2; dCSPalpha; l(3)03988", "gene_names_refseq": "CG6395; CSP32; CSP; Csp; Cys; D-CSP; D.M.CSP; DCSP-1; DNAJC5; DSP/DNAJC5; Dcsp; Dmel\\CG6395; MAB ab49; ab49; anon-WO02059370.50; csp29; csp32; csp; dCSP-2; dCSPalpha; l(3)03988", "protein_names_uniprotkb": "DnaJ homolog subfamily C member 5 homolog; Cysteine string protein", "protein_names_refseq": "CG6395-PF; Csp-PF; cystein string protein; cysteine string protein 3; cysteine string protein, isoform F; cysteine-string protein", "tax_id": 7227, "disease": "neuronal ceroid lipofuscinosis 4 (Disease Ontology:DOID:0110720); neuronal ceroid lipofuscinosis (Disease Ontology:DOID:14503)", "pathway": " (dme:Dmel_CG6395); (R-DME-6798695); (R-DME-888590)", "pathway_count": 3, "publication_count": 17, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;18327897;2129171;25589440;26109356;26109357;8310297;8601435;9799436", "class_list": "", "function": "May have an important role in presynaptic function., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D0IQJ8;O61664;O61665;Q95TD7;Q9VNV1", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane;GO:0043195 terminal bouton;GO:0008021 synaptic vesicle;GO:0061176 type Ib terminal bouton;GO:0061177 type Is terminal bouton", "go_biological_process": "GO:0070050 neuron cellular homeostasis;GO:0006457 protein folding;GO:0006887 exocytosis;GO:0016079 synaptic vesicle exocytosis;GO:1900073 regulation of neuromuscular synaptic transmission", "synthesized_glycan_count": 0, "hit_score": 1.8, "record_id": "Q03751-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P39736-1", "uniprot_id": "BX42_DROME", "mass": 61157.0, "length": 547, "protein_name": "Puff-specific protein Bx42", "gene_name": "Bx42", "organism": "Fruit fly", "refseq_name": "Bx42, isoform B", "refseq_ac": "NP_001259370", "gene_names_uniprotkb": "Bx42; BX42; Bx-42; CG8264; Dmel\\CG8264; Dmel_CG8264; SKIP; Skip; bx42", "gene_names_refseq": "BX42; Bx-42; Bx42; CG8264; Dmel\\CG8264; SKIP; Skip; bx42", "protein_names_uniprotkb": "Puff-specific protein Bx42", "protein_names_refseq": "Bx42, isoform B; Bx42-PB; CG8264-PB; Ski-interacting protein", "tax_id": 7227, "disease": "sciatic neuropathy (Disease Ontology:DOID:11446); breast cancer (Disease Ontology:DOID:1612); pancreatic cancer (Disease Ontology:DOID:1793); breast carcinoma (Disease Ontology:DOID:3459); hepatocellular carcinoma (Disease Ontology:DOID:684)", "pathway": " (dme:Dmel_CG8264); (R-DME-2173795); (R-DME-350054); (R-DME-72163)", "pathway_count": 4, "publication_count": 14, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;1424996;16110336;17569856;17569867;18327897;25589440;26109356;26109357", "class_list": "", "function": "May play a role in chromatin structure and function., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9W390", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding", "go_cellular_component": "GO:0000785 chromatin;GO:0071013 catalytic step 2 spliceosome;GO:0071011 precatalytic spliceosome;GO:0000974 Prp19 complex;GO:0005681 spliceosomal complex", "go_biological_process": "GO:0000398 mRNA splicing, via spliceosome;GO:0035214 eye-antennal disc development;GO:0001700 embryonic development via the syncytial blastoderm", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "P39736-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q27294-1", "uniprot_id": "CAZ_DROME", "mass": 38839.0, "length": 399, "protein_name": "RNA-binding protein cabeza", "gene_name": "caz", "organism": "Fruit fly", "refseq_name": "cabeza, isoform B", "refseq_ac": "NP_523365", "gene_names_uniprotkb": "caz; BcDNA:GM09207; CG3606; Cabeza; Caz; Dmel\\CG3606; Dmel_CG3606; EWSR1; P19; Pen19; SARFH; Sarfh; TFIID; anon-Pen19; cas; dFUS; l(1)5g11; p19; pen19", "gene_names_refseq": "BcDNA:GM09207; CG3606; Cabeza; Caz; Dmel\\CG3606; EWSR1; P19; Pen19; SARFH; Sarfh; TFIID; anon-Pen19; cas; caz; dFUS; l(1)5g11; p19; pen19", "protein_names_uniprotkb": "RNA-binding protein cabeza; P19; Sarcoma-associated RNA-binding fly homolog", "protein_names_refseq": "CG3606-PB; Sarcoma-associated RNA-binding fly homolog; cabeza, isoform B; cabeza; caz-PB; lethal (1) 5g11", "tax_id": 7227, "disease": "amyotrophic lateral sclerosis type 6 (Disease Ontology:DOID:0060198); essential tremor 4 (Disease Ontology:DOID:0111431); sarcoma (Disease Ontology:DOID:1115); neurodegenerative disease (Disease Ontology:DOID:1289); amyotrophic lateral sclerosis (Disease Ontology:DOID:332); Ewing sarcoma (Disease Ontology:DOID:3369); chondrosarcoma (Disease Ontology:DOID:3371); liposarcoma (Disease Ontology:DOID:3382); frontotemporal dementia (Disease Ontology:DOID:9255)", "pathway": " (dme:Dmel_CG3606); (R-DME-674695); (R-DME-6804756); (R-DME-72163); (R-DME-72203); (R-DME-73776); (R-DME-73779); (R-DME-75953); (R-DME-76042); (R-DME-9770562)", "pathway_count": 10, "publication_count": 15, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357;3031652;7623847;7708500", "class_list": "", "function": "May participate in a function common to the expression of most genes transcribed by RNA polymerase II., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 9, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q24445;Q8T3M2;Q9VXI4", "ec_number_list": "", "go_molecular_function": "GO:0003682 chromatin binding;GO:0003723 RNA binding;GO:0003729 mRNA binding;GO:0008270 zinc ion binding;GO:0003712 transcription coregulator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0071013 catalytic step 2 spliceosome;GO:0005669 transcription factor TFIID complex", "go_biological_process": "GO:0048749 compound eye development;GO:0008344 adult locomotory behavior;GO:0051124 synaptic assembly at neuromuscular junction;GO:0006355 regulation of DNA-templated transcription;GO:0006367 transcription initiation at RNA polymerase II promoter", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "Q27294-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P20228-1", "uniprot_id": "DCE_DROME", "mass": 57819.0, "length": 510, "protein_name": "Glutamate decarboxylase", "gene_name": "Gad1", "organism": "Fruit fly", "refseq_name": "glutamic acid decarboxylase 1, isoform D", "refseq_ac": "NP_001261396", "gene_names_uniprotkb": "Gad1; CG14994; DGAD1; DGad1; Dm-GDC; Dmel\\CG14994; Dmel_CG14994; GAD-1; GAD1; GAD[[1]]; GAD; Gad; Glb; dGad1; dgad1; gad1; gad; l(3)64An; l(3)SH10", "gene_names_refseq": "CG14994; DGAD1; DGad1; Dm-GDC; Dmel\\CG14994; GAD-1; GAD1; GAD[[1]]; GAD; Gad1; Gad; Glb; dGad1; dgad1; gad1; gad; l(3)64An; l(3)SH10", "protein_names_uniprotkb": "Glutamate decarboxylase; 4.1.1.15; GAD", "protein_names_refseq": "CG14994-PD; GABA synthetase; Gad1-PD; glutamate decarboxylase; glutamatic acid decarboxylase; glutamic acid decarboxylase 1, isoform D; glutamic acid decarboxylase 1; glutamic acid decarboxylase-1; vesicular glutamic acid decarboxylase", "tax_id": 7227, "disease": "spastic cerebral palsy (Disease Ontology:DOID:0050669); alcohol dependence (Disease Ontology:DOID:0050741); withdrawal disorder (Disease Ontology:DOID:0060001); autism spectrum disorder (Disease Ontology:DOID:0060041); developmental and epileptic encephalopathy 89 (Disease Ontology:DOID:0112223); gestational diabetes (Disease Ontology:DOID:11714); alcohol use disorder (Disease Ontology:DOID:1574); drug psychosis (Disease Ontology:DOID:1742); epilepsy (Disease Ontology:DOID:1826); anxiety disorder (Disease Ontology:DOID:2030); transient cerebral ischemia (Disease Ontology:DOID:224); morphine dependence (Disease Ontology:DOID:2560); bipolar disorder (Disease Ontology:DOID:3312); schizophrenia (Disease Ontology:DOID:5419); amphetamine abuse (Disease Ontology:DOID:670); colorectal cancer (Disease Ontology:DOID:9256); diabetes mellitus (Disease Ontology:DOID:9351); type 1 diabetes mellitus (Disease Ontology:DOID:9744); heroin dependence (Disease Ontology:DOID:9976)", "pathway": " (dme:Dmel_CG14994); (R-DME-888568); (R-DME-888590)", "pathway_count": 3, "publication_count": 14, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;1689376;17569856;17569867;24241395;25589440;26109356;26109357", "class_list": "", "function": "Catalyzes the production of GABA., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 19, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A4V1G1;Q9VZI7", "ec_number_list": "4.1.1.-;4.1.1.15;4.1.-.-", "go_molecular_function": "GO:0030170 pyridoxal phosphate binding;GO:0004351 glutamate decarboxylase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0007528 neuromuscular junction development;GO:0007416 synapse assembly;GO:0009612 response to mechanical stimulus;GO:0008355 olfactory learning;GO:0006538 L-glutamate catabolic process", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "P20228-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P54362-1", "uniprot_id": "AP3D_DROME", "mass": 114846.0, "length": 1034, "protein_name": "AP-3 complex subunit delta", "gene_name": "g", "organism": "Fruit fly", "refseq_name": "garnet, isoform B", "refseq_ac": "NP_524785", "gene_names_uniprotkb": "g; AP-3delta; AP3delta; CG10986; CG11197; Dmel\\CG10986; Dmel_CG10986; apl5; cg11197; delta; l(1)Mc19", "gene_names_refseq": "AP-3delta; AP3delta; CG10986; CG11197; Dmel\\CG10986; apl5; cg11197; delta; g; l(1)Mc19", "protein_names_uniprotkb": "AP-3 complex subunit delta; Delta adaptin subunit of AP-3; Delta-adaptin; Garnet protein", "protein_names_refseq": "AP-3, delta subunit; CG10986-PB; adaptor protein complex 3, delta subunit; g-PB; garnet, isoform B; garnet; lethal(1)Mc19; salmon", "tax_id": 7227, "disease": "Hermansky-Pudlak syndrome 1 (Disease Ontology:DOID:0060539); Hermansky-Pudlak syndrome 2 (Disease Ontology:DOID:0060540); platelet storage pool deficiency (Disease Ontology:DOID:2223); Hermansky-Pudlak syndrome (Disease Ontology:DOID:3753)", "pathway": " (dme:Dmel_CG10986)", "pathway_count": 1, "publication_count": 15, "publication_id_list": "10659786;10731132;12537568;12537572;12537573;12537574;16110336;17372656;17569856;17569867;18327897;25589440;26109356;26109357;9303295", "class_list": "", "function": "May be a coat protein involved in the formation of specialized structures like pigment granules., [UniProtKB]; Part of the AP-3 complex, an adapter-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes (By similarity)., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "O16015;O45031;Q9VY96", "ec_number_list": "", "go_molecular_function": "GO:0140312 cargo adaptor activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005798 Golgi-associated vesicle;GO:0005829 cytosol;GO:0043195 terminal bouton;GO:0005770 late endosome", "go_biological_process": "GO:0008057 eye pigment granule organization;GO:0006897 endocytosis;GO:0007220 Notch receptor processing;GO:0016192 vesicle-mediated transport;GO:0006726 eye pigment biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "P54362-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q24255-1", "uniprot_id": "BARH1_DROME", "mass": 56083.0, "length": 544, "protein_name": "Homeobox protein B-H1", "gene_name": "B-H1", "organism": "Fruit fly", "refseq_name": "BarH1, isoform A", "refseq_ac": "NP_523387", "gene_names_uniprotkb": "B-H1; B-H; BH1; Bar H1; Bar-H1; BarHI; BarH; Barh1; Bar; CG5529; Dmel\\CG5529; Dmel_CG5529; bar-h1; barH1; barh1", "gene_names_refseq": "B-H1; B-H; BH1; Bar H1; Bar-H1; BarHI; BarH; Barh1; Bar; CG5529; Dmel\\CG5529; bar-h1; barH1; barh1", "protein_names_uniprotkb": "Homeobox protein B-H1; Homeobox protein BarH1", "protein_names_refseq": "B-H1-PA; Bar-H1; BarH1, isoform A; CG5529-PA", "tax_id": 7227, "disease": "oral squamous cell carcinoma (Disease Ontology:DOID:0050866); triple-receptor negative breast cancer (Disease Ontology:DOID:0060081); stomach cancer (Disease Ontology:DOID:10534); Alzheimer's disease (Disease Ontology:DOID:10652); high grade glioma (Disease Ontology:DOID:3070); colorectal cancer (Disease Ontology:DOID:9256)", "pathway": " (dme:Dmel_CG5529)", "pathway_count": 1, "publication_count": 17, "publication_id_list": "10068639;10648235;10731132;12537568;12537569;12537572;12537573;12537574;1346120;1350558;16110336;1674606;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "B-H1 and B-H2 are regulated by members of the wg signaling pathway; wg and dpp. B-H1 and B-H2 are coexpressed and functionally required in R1 and R6 receptor cells and primary pigment cells for normal eye development. Coexpression is also required for the fate determination of external sensory organs, formation of notal microchaetae, formation of presutural macrochaetae, antennal development and for distal leg morphogenesis; segmentation and specification of tarsal segments 3-5., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 6, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q9VX54", "ec_number_list": "", "go_molecular_function": "GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0008052 sensory organ boundary specification;GO:0008057 eye pigment granule organization;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006357 regulation of transcription by RNA polymerase II;GO:0045892 negative regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 1.8, "record_id": "Q24255-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P15370-1", "uniprot_id": "EGON_DROME", "mass": 39561.0, "length": 373, "protein_name": "Protein embryonic gonad", "gene_name": "eg", "organism": "Fruit fly", "refseq_name": "eagle, isoform A", "refseq_ac": "NP_524206", "gene_names_uniprotkb": "eg; CG7383; Dmel\\CG7383; Dmel_CG7383; EGON; Egl; Egon; Eg; NR0A3; T1; eag; egl; egon; spry; spy", "gene_names_refseq": "CG7383; Dmel\\CG7383; EGON; Egl; Egon; Eg; NR0A3; T1; eag; egl; egon; eg; spy", "protein_names_uniprotkb": "Protein embryonic gonad; Nuclear receptor subfamily 0 group A member 3; Protein eagle; Protein spready", "protein_names_refseq": "CG7383-PA; T1 transcription unit; eagle, isoform A; eagle; eg-PA; embryonic gonad; spready", "tax_id": 7227, "disease": "prostate cancer (Disease Ontology:DOID:10283); Alzheimer's disease (Disease Ontology:DOID:10652); osteoporosis (Disease Ontology:DOID:11476); vitiligo (Disease Ontology:DOID:12306); breast cancer (Disease Ontology:DOID:1612); melanoma (Disease Ontology:DOID:1909); arteriosclerosis (Disease Ontology:DOID:2349); Leydig cell tumor (Disease Ontology:DOID:2696); endometriosis (Disease Ontology:DOID:289); lymphangioleiomyomatosis (Disease Ontology:DOID:3319); coronary artery disease (Disease Ontology:DOID:3393); breast carcinoma (Disease Ontology:DOID:3459); lung non-small cell carcinoma (Disease Ontology:DOID:3908); systemic scleroderma (Disease Ontology:DOID:418); macular degeneration (Disease Ontology:DOID:4448); myocardial infarction (Disease Ontology:DOID:5844); migraine (Disease Ontology:DOID:6364); pulmonary hypertension (Disease Ontology:DOID:6432); sporadic breast cancer (Disease Ontology:DOID:8029); osteoarthritis (Disease Ontology:DOID:8398); in situ carcinoma (Disease Ontology:DOID:8719); type 2 diabetes mellitus (Disease Ontology:DOID:9352)", "pathway": " (dme:Dmel_CG7383); (R-DME-1251985); (R-DME-3371497); (R-DME-383280); (R-DME-5625886); (R-DME-5689880); (R-DME-5689896); (R-DME-8931987); (R-DME-8939211); (R-DME-8940973); (R-DME-9009391); (R-DME-9018519); (R-DME-9841251)", "pathway_count": 13, "publication_count": 13, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;2555153;25589440;26109356;26109357;8625804", "class_list": "", "function": "May play a critical role in development of the progeny of eagle-positive neuroblasts., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 22, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q0IGS4;Q9VNY0", "ec_number_list": "", "go_molecular_function": "GO:0034056 estrogen response element binding;GO:0008270 zinc ion binding;GO:0004879 nuclear receptor activity;GO:0003700 DNA-binding transcription factor activity;GO:0043565 sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0000785 chromatin", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0030154 cell differentiation;GO:0006355 regulation of DNA-templated transcription;GO:0007417 central nervous system development", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "P15370-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q24337-1", "uniprot_id": "ER_DROME", "mass": 12188.0, "length": 104, "protein_name": "Protein enhancer of rudimentary", "gene_name": "e(r)", "organism": "Fruit fly", "refseq_name": "enhancer of rudimentary, isoform C", "refseq_ac": "NP_001259363", "gene_names_uniprotkb": "e(r); CG1871; Dmel\\CG1871; Dmel_CG1871; ER_DROME; ER", "gene_names_refseq": "CG1871; Dmel\\CG1871; ER_DROME; ER; e(r)", "protein_names_uniprotkb": "Protein enhancer of rudimentary", "protein_names_refseq": "CG1871-PC; e(r)-PC; enhancer of rudimentary, isoform C", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG1871)", "pathway_count": 1, "publication_count": 14, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357;7896098;9074495", "class_list": "", "function": "Acts as an enhancer of the rudimentary gene. Has a role in pyrimidine biosynthesis and the cell cycle., [UniProtKB, PubMed, PubMed, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A4V463;Q9W3B1", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006221 pyrimidine nucleotide biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "Q24337-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P13706-3", "uniprot_id": "GPDA_DROME", "mass": 39329.0, "length": 360, "protein_name": "Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic", "gene_name": "Gpdh1", "organism": "Fruit fly", "refseq_name": "Glycerol-3-phosphate dehydrogenase 1, isoform E", "refseq_ac": "NP_001260111", "gene_names_uniprotkb": "Gpdh1; CG9042; Gpdh", "gene_names_refseq": "CG9042; DROGPDHA; DmG3PDH; Dmel\\CG9042; G3PDH; G3pdh; GAPDH; GPDA; GPDH-1; GPDH1; GPDH; GPD; Gdh; Gpdh1; Gpdh; Gpd; alpha-GPDH-1; alpha-GPDH; alpha-GPD; alpha-Gpdh; alphaGPDH; alphaGpdh-1; alphaGpdh; alphaGpd; dGpdh; gpdh-1; gpdh; sn-Gpdh", "protein_names_uniprotkb": "Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic; 1.1.1.8; GPD-C; GPDH-C", "protein_names_refseq": "5' gene; Alpha-Glycerophosphate dehydrogenase; CG9042-PE; Glycerol-3-phosphate dehydrogenase 1, isoform E; Gpdh1-PE; alpha glycerophosphate dehydrogenase 1; alpha-glycerol phosphate dehydrogenase; alpha-glycerol-3-phosphate dehydrogenase; glycerol 3 phosphate dehydrogenase; glycerophosphate dehydrogenase; sn-glycerol 3-phosphate dehydrogenase; sn-glycerol-3-phosphate dehydrogenase", "tax_id": 7227, "disease": "Brugada syndrome 2 (Disease Ontology:DOID:0110219)", "pathway": " (dme:Dmel_CG9042); (R-DME-1483166)", "pathway_count": 2, "publication_count": 10, "publication_id_list": "10731132;12537569;12537572;2500660;2511555;2839508;3755720;7633467;7993372;8094564", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "B5RIM9;M9PC43;M9PET0;Q27590;Q27925;Q95077;Q95TV4;Q9VML0", "ec_number_list": "1.1.1.8", "go_molecular_function": "GO:0042803 protein homodimerization activity;GO:0051287 NAD binding;GO:0047952 glycerol-3-phosphate dehydrogenase [NAD(P)+] activity;GO:0141152 glycerol-3-phosphate dehydrogenase (NAD+) activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0030018 Z disc;GO:0031430 M band", "go_biological_process": "GO:0006650 glycerophospholipid metabolic process;GO:0046167 glycerol-3-phosphate biosynthetic process;GO:0006127 glycerol-3-phosphate shuttle;GO:0006641 triglyceride metabolic process;GO:0006096 glycolytic process", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "P13706-3", "record_type": "protein" }, { "uniprot_canonical_ac": "P14484-1", "uniprot_id": "CUPP_DROME", "mass": 20633.0, "length": 184, "protein_name": "Pupal cuticle protein", "gene_name": "Pcp", "organism": "Fruit fly", "refseq_name": "pupal cuticle protein", "refseq_ac": "NP_476673", "gene_names_uniprotkb": "Pcp; CG3440", "gene_names_refseq": "CG3440; DMCPGART; DmelPcp; Dmel\\CG3440; Gart; PCP-Gart; Pcpgart; Pcp", "protein_names_uniprotkb": "Pupal cuticle protein", "protein_names_refseq": "CG3440-PA; Pcp-PA; gart intron gene; gart intronic gene; pupal cuticle protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG3440)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "10731132;12537572;3079672;3123310", "class_list": "", "function": "Component of the cuticle of the pupa of fruit fly., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A8WHK2;Q9VM52", "ec_number_list": "", "go_molecular_function": "GO:0008010 structural constituent of chitin-based larval cuticle;GO:0008011 structural constituent of pupal chitin-based cuticle", "go_cellular_component": "GO:0062129 chitin-based extracellular matrix", "go_biological_process": "GO:0040003 chitin-based cuticle development;GO:0046529 imaginal disc fusion, thorax closure", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P14484-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P15425-1", "uniprot_id": "CYPR_DROME", "mass": 26351.0, "length": 237, "protein_name": "Peptidyl-prolyl cis-trans isomerase, rhodopsin-specific isozyme", "gene_name": "ninaA", "organism": "Fruit fly", "refseq_name": "neither inactivation nor afterpotential A", "refseq_ac": "NP_476656", "gene_names_uniprotkb": "ninaA; CG3966", "gene_names_refseq": "CG3966; Dmel\\CG3966; NINAA; NinaA; ninA; ninaA", "protein_names_uniprotkb": "Peptidyl-prolyl cis-trans isomerase, rhodopsin-specific isozyme; 5.2.1.8; PPIase; Rotamase", "protein_names_refseq": "CG3966-PA; either inactivation nor afterpotential A; neither inactivation nor after potential; neither inactivation nor afterpotential A; ninaA-PA", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG3966)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "10731132;12537572;1644830;1707759;2493138;2664782;33925313", "class_list": "", "function": "PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Acts on the folding of rhodopsin RH1 and RH2 (but not RH3) and is required for visual transduction., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 1, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 1, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 1, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q9VPV0", "ec_number_list": "5.2.1.8", "go_molecular_function": "GO:0016018 cyclosporin A binding;GO:0003755 peptidyl-prolyl cis-trans isomerase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005788 endoplasmic reticulum lumen;GO:0016020 membrane;GO:0005789 endoplasmic reticulum membrane;GO:0031410 cytoplasmic vesicle", "go_biological_process": "GO:0007601 visual perception;GO:0006457 protein folding;GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress;GO:0006491 N-glycan processing;GO:0006458 'de novo' protein folding", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "P15425-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P16395-1", "uniprot_id": "ACM1_DROME", "mass": 86623.0, "length": 805, "protein_name": "Muscarinic acetylcholine receptor DM1", "gene_name": "mAChR-A", "organism": "Fruit fly", "refseq_name": "muscarinic acetylcholine Receptor, A-type, isoform B", "refseq_ac": "NP_523844", "gene_names_uniprotkb": "mAChR-A; AcrC; CG4356; mAcR-60C", "gene_names_refseq": "Acr60C; AcrC; CG4356; DM1; Dm-mAChR-A; Dm1; Dmel\\CG4356; mAChR A; mAChR-1; mAChR-A1; mAChR-A; mAChR; mAcR-60C; mAcR60C; mAcR; mAchR", "protein_names_uniprotkb": "Muscarinic acetylcholine receptor DM1", "protein_names_refseq": "A-type mAChR; CG4356-PB; mAChR-A-PB; muscarinic acetylcholine Receptor, A-type, isoform B; muscarinic acetylcholine receptor 60C; muscarinic acetylcholine receptor; muscarinic receptor", "tax_id": 7227, "disease": "Lambert-Eaton myasthenic syndrome (Disease Ontology:DOID:0050214); small cell carcinoma (Disease Ontology:DOID:0050685); nicotine dependence (Disease Ontology:DOID:0050742); megacystis-microcolon-intestinal hypoperistalsis syndrome (Disease Ontology:DOID:0060610); prune belly syndrome (Disease Ontology:DOID:0060889); Chagas disease (Disease Ontology:DOID:12140); major depressive disorder (Disease Ontology:DOID:1470); alcohol use disorder (Disease Ontology:DOID:1574); depressive disorder (Disease Ontology:DOID:1596); cannabis dependence (Disease Ontology:DOID:1849); asthma (Disease Ontology:DOID:2841); chronic obstructive pulmonary disease (Disease Ontology:DOID:3083); bipolar disorder (Disease Ontology:DOID:3312); bladder disease (Disease Ontology:DOID:365); pulmonary fibrosis (Disease Ontology:DOID:3770); myasthenia gravis (Disease Ontology:DOID:437); schizophrenia (Disease Ontology:DOID:5419); congestive heart failure (Disease Ontology:DOID:6000); heroin dependence (Disease Ontology:DOID:9976)", "pathway": " (dme:Dmel_CG4356); (R-DME-390648); (R-DME-390650); (R-DME-418594); (R-DME-8856825); (R-DME-8856828)", "pathway_count": 6, "publication_count": 6, "publication_id_list": "10731132;12537572;23604020;2507354;2510174;7550280", "class_list": "", "function": "The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover. May have a role in the processing of olfactory and mechanosensory signals; regulation of neurosecretion., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 4, "predicted_n_glycosites": 3, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 19, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "G4LU59;M9NHK8;M9NKN3;Q1ECB8;Q8MLP2;Q9W180", "ec_number_list": "", "go_molecular_function": "GO:0016907 G protein-coupled acetylcholine receptor activity;GO:0008227 G protein-coupled amine receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane;GO:0030425 dendrite;GO:0045202 synapse;GO:0045211 postsynaptic membrane", "go_biological_process": "GO:0007197 adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway;GO:0007213 G protein-coupled acetylcholine receptor signaling pathway;GO:0007187 G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007268 chemical synaptic transmission;GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P16395-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P16548-1", "uniprot_id": "A95EF_DROME", "mass": 5405.0, "length": 52, "protein_name": "Accessory gland-specific peptide 95EF", "gene_name": "Acp95EF", "organism": "Fruit fly", "refseq_name": "accessory gland protein 95EF", "refseq_ac": "NP_524898", "gene_names_uniprotkb": "Acp95EF; CG17924; MSP316; Mst95E", "gene_names_refseq": "Acp95EF; Acp; CG17924; DTA-D; DTA-E; Dmel\\CG17924; Mst95E; Mst95F; mst 316; mst(3)ag-3; mst-3; mst316F; mst316", "protein_names_uniprotkb": "Accessory gland-specific peptide 95EF; Male accessory gland secretory protein 316", "protein_names_refseq": "Acp95EF-PA; CG17924-PA; accessory gland protein 95EF; accessory gland-specific peptide 95EF", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG17924)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "10731132;12537572;2109712", "class_list": "", "function": "This protein may be a precursor of secreted proteins and peptide hormones., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A8E717;A8E740;Q9VCB0", "ec_number_list": "", "go_molecular_function": "GO:0005179 hormone activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0007320 insemination;GO:0007618 mating", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "P16548-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P16909-1", "uniprot_id": "18C_DROME", "mass": 24472.0, "length": 215, "protein_name": "Histone-like protein 18C", "gene_name": "Mst77F", "organism": "Fruit fly", "refseq_name": "Male-specific transcript 77F", "refseq_ac": "NP_524188", "gene_names_uniprotkb": "Mst77F; 18c; CG3354; anon-77F", "gene_names_refseq": "18c; CG3354; Dmel\\CG3354; MST77F; Mst77F; Mst77f; R1-18c; ms(3)nc3; mst77F; nc3", "protein_names_uniprotkb": "Histone-like protein 18C", "protein_names_refseq": "CG3354-PA; Male-specific transcript 77F; Mst77F-PA; male sterile (3) nc3", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG3354)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "10731132;12537572;3215511", "class_list": "", "function": "Not known. Encoded in the intron of cAMP-dependent protein kinase regulatory chain type I., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q86NM1;Q9VPA8", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0036126 sperm flagellum;GO:0000785 chromatin", "go_biological_process": "GO:0035092 sperm DNA condensation", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "P16909-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P16912-1", "uniprot_id": "KAPC3_DROME", "mass": 65407.0, "length": 583, "protein_name": "cAMP-dependent protein kinase catalytic subunit 3", "gene_name": "Pka-C3", "organism": "Fruit fly", "refseq_name": "protein kinase, cAMP-dependent, catalytic subunit 3, isoform A", "refseq_ac": "NP_524097", "gene_names_uniprotkb": "Pka-C3; CG6117; DC2", "gene_names_refseq": "5-23; CG6117; DC2; Dmel\\CG6117; Dpck; PKA C3; PKA-C-3; PKA-C3; PKAC3; PKA; Pk72A; Pk?5; Pka-C3; pka-C3", "protein_names_uniprotkb": "cAMP-dependent protein kinase catalytic subunit 3; 2.7.11.1; Protein kinase DC2", "protein_names_refseq": "CG6117-PA; Pka-C3-PA; Protein-kinase-like-72A; cAMP-activated protein kinase A; cAMP-dependent protein kinase 3; protein kinase, cAMP-dependent, catalytic subunit 3, isoform A", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG6117)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "10731132;12537569;12537572;3215511;8601490", "class_list": "", "function": "Does not have an essential role in development., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q86BP5;Q8MSN9;Q9VUV5", "ec_number_list": "2.7.11.17;2.7.11.1;2.7.11.13;2.7.11.24;2.7.11.22;2.7.11.21;5.6.1.8;2.7.11.11;2.7.11.23;2.7.12.1;2.7.11.25;2.7.11.12;2.7.12.2;2.7.10.2;2.7.11.39", "go_molecular_function": "GO:0005524 ATP binding;GO:0004691 cAMP-dependent protein kinase activity;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005829 cytosol;GO:0005952 cAMP-dependent protein kinase complex", "go_biological_process": "GO:0007155 cell adhesion;GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007476 imaginal disc-derived wing morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P16912-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P17336-1", "uniprot_id": "CATA_DROME", "mass": 57150.0, "length": 506, "protein_name": "Catalase", "gene_name": "Cat", "organism": "Fruit fly", "refseq_name": "catalase", "refseq_ac": "NP_536731", "gene_names_uniprotkb": "Cat; CG6871", "gene_names_refseq": "CAT1; CATA; CAT; CG6871; CT21282; Cat-A; CatA; Cat; DMCATHPO; DROCATHPO; DmCAT; Dmel\\CG6871; U00145; bs36h11.y1; catalase; cat; dCAT; dCat", "protein_names_uniprotkb": "Catalase; 1.11.1.6", "protein_names_refseq": "CATHPO; CG6871-PA; Cat-PA; SOD; catalase; cytosolic catalase", "tax_id": 7227, "disease": "pterygium (Disease Ontology:DOID:0002116); chronic venous insufficiency (Disease Ontology:DOID:0050853); colitis (Disease Ontology:DOID:0060180); alcohol-associated liver disease (Disease Ontology:DOID:0070658); colorectal carcinoma (Disease Ontology:DOID:0080199); Graves ophthalmopathy (Disease Ontology:DOID:0081120); sensorineural hearing loss (Disease Ontology:DOID:10003); osteonecrosis (Disease Ontology:DOID:10159); Raynaud disease (Disease Ontology:DOID:10300); pneumoconiosis (Disease Ontology:DOID:10316); retinitis pigmentosa (Disease Ontology:DOID:10584); otitis media (Disease Ontology:DOID:10754); hypertension (Disease Ontology:DOID:10763); gastric ulcer (Disease Ontology:DOID:10808); essential hypertension (Disease Ontology:DOID:10825); sciatic neuropathy (Disease Ontology:DOID:11446); bronchopulmonary dysplasia (Disease Ontology:DOID:11650); optic neuritis (Disease Ontology:DOID:1210); tympanosclerosis (Disease Ontology:DOID:1214); vitiligo (Disease Ontology:DOID:12306); Graves' disease (Disease Ontology:DOID:12361); newborn respiratory distress syndrome (Disease Ontology:DOID:12716); Huntington's disease (Disease Ontology:DOID:12858); neurodegenerative disease (Disease Ontology:DOID:1289); dilated cardiomyopathy (Disease Ontology:DOID:12930); proliferative diabetic retinopathy (Disease Ontology:DOID:13207); background diabetic retinopathy (Disease Ontology:DOID:13208); Behcet's disease (Disease Ontology:DOID:13241); angle-closure glaucoma (Disease Ontology:DOID:13550); cholestasis (Disease Ontology:DOID:13580); hypothyroidism (Disease Ontology:DOID:1459); alcohol use disorder (Disease Ontology:DOID:1574); depressive disorder (Disease Ontology:DOID:1596); keratosis (Disease Ontology:DOID:161); cystitis (Disease Ontology:DOID:1679); pancreatic cancer (Disease Ontology:DOID:1793); melanoma (Disease Ontology:DOID:1909); brain ischemia (Disease Ontology:DOID:2316); nephrosis (Disease Ontology:DOID:2527); acatalasia (Disease Ontology:DOID:2582); pseudoxanthoma elasticum (Disease Ontology:DOID:2738); asthma (Disease Ontology:DOID:2841); laryngeal squamous cell carcinoma (Disease Ontology:DOID:2876); familial Mediterranean fever (Disease Ontology:DOID:2987); chronic obstructive pulmonary disease (Disease Ontology:DOID:3083); breast adenocarcinoma (Disease Ontology:DOID:3458); toxic encephalopathy (Disease Ontology:DOID:3602); gastric adenocarcinoma (Disease Ontology:DOID:3717); pulmonary fibrosis (Disease Ontology:DOID:3770); papillary thyroid carcinoma (Disease Ontology:DOID:3969); ureteral obstruction (Disease Ontology:DOID:5199); retinal disease (Disease Ontology:DOID:5679); myocardial infarction (Disease Ontology:DOID:5844); nephrolithiasis (Disease Ontology:DOID:585); congestive heart failure (Disease Ontology:DOID:6000); fibromyalgia (Disease Ontology:DOID:631); acne (Disease Ontology:DOID:6543); amphetamine abuse (Disease Ontology:DOID:670); hepatocellular carcinoma (Disease Ontology:DOID:684); end stage renal disease (Disease Ontology:DOID:783); hyperthyroidism (Disease Ontology:DOID:7998); scabies (Disease Ontology:DOID:8295); cataract (Disease Ontology:DOID:83); lung disease (Disease Ontology:DOID:850); bacterial pneumonia (Disease Ontology:DOID:874); seborrheic dermatitis (Disease Ontology:DOID:8741); psoriasis (Disease Ontology:DOID:8893); diabetic retinopathy (Disease Ontology:DOID:8947); cutaneous leishmaniasis (Disease Ontology:DOID:9111); pemphigus (Disease Ontology:DOID:9182); lichen planus (Disease Ontology:DOID:9201); phenylketonuria (Disease Ontology:DOID:9281); type 2 diabetes mellitus (Disease Ontology:DOID:9352); steatotic liver disease (Disease Ontology:DOID:9452); stomatitis (Disease Ontology:DOID:9637); senile cataract (Disease Ontology:DOID:9669); neovascular inflammatory vitreoretinopathy (Disease Ontology:DOID:9719)", "pathway": " (dme:Dmel_CG6871); (R-DME-3299685); (R-DME-6798695); (R-DME-9033241)", "pathway_count": 4, "publication_count": 8, "publication_id_list": "10731132;12537569;12537572;15952742;2362827;30802236;8500545;8660653", "class_list": "", "function": "Catalyzes the degradation of hydrogen peroxide (H(2)O(2)) generated by peroxisomal oxidases to water and oxygen, thereby protecting cells from the toxic effects of hydrogen peroxide., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 77, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9VVT1", "ec_number_list": "2.3.1.42;2.4.1.186;5.4.2.7;5.4.2.-;1.1.3.15;3.2.1.31;1.1.1.42;6.2.1.3;2.4.2.1;2.7.11.24;2.7.1.40;4.1.2.13;2.7.4.6;2.4.2.7;3.6.5.-;1.11.1.6;3.4.24.56;5.3.1.9;2.7.1.11;1.1.1.205;3.4.22.-;3.6.4.12;1.14.13.39;1.3.3.6;3.6.4.6;1.16.3.1;2.7.1.35;2.3.2.5;3.4.24.-;2.3.2.27;2.7.1.1;5.2.1.8;3.4.19.-;1.11.1.24;5.6.1.5;5.4.2.11;5.4.2.4;2.3.-.-;2.3.1.137;3.2.1.23;3.6.1.5;3.6.4.13;2.3.1.7;5.1.99.4;3.3.2.6;2.3.1.176;2.3.1.16;2.3.1.155;3.5.4.5;4.1.3.4;1.4.3.3;1.-.-.-;2.7.11.22;2.7.11.23;1.1.1.184;4.2.1.24;5.4.2.2;3.4.-.-;1.11.2.-;5.3.3.8;3.4.21.-;2.4.1.25;3.2.1.33;2.7.1.-;2.6.1.44;5.3.3.21;3.5.4.6;2.3.2.26", "go_molecular_function": "GO:0046872 metal ion binding;GO:0020037 heme binding;GO:0004096 catalase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005777 peroxisome;GO:0005782 peroxisomal matrix;GO:0005829 cytosol;GO:0016008 major mitochondrial derivative", "go_biological_process": "GO:0048167 regulation of synaptic plasticity;GO:0042542 response to hydrogen peroxide;GO:0003007 heart morphogenesis;GO:0042744 hydrogen peroxide catabolic process;GO:0072593 reactive oxygen species metabolic process", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "P17336-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P17644-1", "uniprot_id": "ACH2_DROME", "mass": 65506.0, "length": 576, "protein_name": "Acetylcholine receptor subunit alpha-like 2", "gene_name": "nAChRalpha2", "organism": "Fruit fly", "refseq_name": "nicotinic acetylcholine receptor alpha2, isoform A", "refseq_ac": "NP_524482", "gene_names_uniprotkb": "nAChRalpha2; Acr96Ab; AcrE; CG6844; nAcRalpha-96Ab; sad", "gene_names_refseq": "Acr96Ab; AcrE; CG6844-PA; CG6844; D[a2]; Da2; Dalpha2/SAD; Dalpha2; Dalpha; Dmalpha2; Dmel\\CG6844; SAD; alpha2; alpha[[2]]; da2; nAChR Dalpha2; nAChR-alpha96Ab; nAChRa2; nAChRalpha-96A; nAChRalpha2; nAChR; nAcRalpha-96Ab; nAcRs; nAchRalpha-96Ab; nAcr96Ab; sad", "protein_names_uniprotkb": "Acetylcholine receptor subunit alpha-like 2; Nicotinic acetylcholine receptor alpha 2", "protein_names_refseq": "CG6844-PA; Dalpha2 nicotimic acetylcholine receptor; Dalpha2; SAD; drosophila alpha-like subunit 2; nAChRalpha2-PA; nicotinic acetylcholine receptor alpha 96Ab; nicotinic acetylcholine receptor alpha subunit gene at 96AB; nicotinic acetylcholine receptor alpha-2; nicotinic acetylcholine receptor alpha2, isoform A; second alpha-like subunit of drosophila", "tax_id": 7227, "disease": "nicotine dependence (Disease Ontology:DOID:0050742); autosomal dominant nocturnal frontal lobe epilepsy 1 (Disease Ontology:DOID:0060682); autosomal dominant nocturnal frontal lobe epilepsy 4 (Disease Ontology:DOID:0060685); congenital myasthenic syndrome 4A (Disease Ontology:DOID:0110678); congenital myasthenic syndrome 4C (Disease Ontology:DOID:0110679); Alzheimer's disease (Disease Ontology:DOID:10652); Lewy body dementia (Disease Ontology:DOID:12217); alcohol use disorder (Disease Ontology:DOID:1574); depressive disorder (Disease Ontology:DOID:1596); asthma (Disease Ontology:DOID:2841); congenital myasthenic syndrome (Disease Ontology:DOID:3635)", "pathway": " (dme:Dmel_CG6844); (R-DME-629587); (R-DME-629594); (R-DME-629597); (R-DME-6798695)", "pathway_count": 5, "publication_count": 6, "publication_id_list": "10731132;12537569;12537572;1697262;2114015;2117557", "class_list": "", "function": "After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane., [UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 11, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "Q0KI18;Q9VC73", "ec_number_list": "", "go_molecular_function": "GO:0004888 transmembrane signaling receptor activity;GO:0022848 acetylcholine-gated monoatomic cation-selective channel activity;GO:1904315 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential;GO:0005231 excitatory extracellular ligand-gated monoatomic ion channel activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005892 acetylcholine-gated channel complex;GO:0045202 synapse;GO:0045211 postsynaptic membrane;GO:0043005 neuron projection", "go_biological_process": "GO:0007271 synaptic transmission, cholinergic;GO:0042391 regulation of membrane potential;GO:0007268 chemical synaptic transmission;GO:0034220 monoatomic ion transmembrane transport;GO:0098655 monoatomic cation transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P17644-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P17719-1", "uniprot_id": "DYR_DROME", "mass": 20775.0, "length": 182, "protein_name": "Dihydrofolate reductase", "gene_name": "Dhfr", "organism": "Fruit fly", "refseq_name": "dihydrofolate reductase, isoform B", "refseq_ac": "NP_001036720", "gene_names_uniprotkb": "Dhfr; CG14887", "gene_names_refseq": "CG14887; DHFR; Dhfr; Dmel\\CG14887; dhfr", "protein_names_uniprotkb": "Dihydrofolate reductase; 1.5.1.3", "protein_names_refseq": "CG14887-PB; Dhfr-PB; dihydrofolate reductase, isoform B; dihydrofolate reductase", "tax_id": 7227, "disease": "cancer (Disease Ontology:DOID:162); acute lymphoblastic leukemia (Disease Ontology:DOID:9952)", "pathway": " (dme:Dmel_CG14887); (R-DME-196757)", "pathway_count": 2, "publication_count": 5, "publication_id_list": "10731132;12537572;14526388;2116172;8195153", "class_list": "", "function": "By interacting with vestigial (vg), may control genes involved in DNA replication., [UniProtKB]; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A4V302;Q9VEU4", "ec_number_list": "1.5.1.3", "go_molecular_function": "GO:0004146 dihydrofolate reductase activity;GO:0050661 NADP binding", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0046654 tetrahydrofolate biosynthetic process;GO:0006260 DNA replication;GO:0006730 one-carbon metabolic process;GO:0046655 folic acid metabolic process;GO:0046452 dihydrofolate metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P17719-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P17886-1", "uniprot_id": "CRN_DROME", "mass": 84262.0, "length": 702, "protein_name": "Protein crooked neck", "gene_name": "crn", "organism": "Fruit fly", "refseq_name": "crooked neck", "refseq_ac": "NP_477118", "gene_names_uniprotkb": "crn; CG3193", "gene_names_refseq": "62D9.a; CG18842; CG3193; Crn; Dmel\\CG3193; EG:30B8.1; N10; N5; RC63; crn; l(1)2Fa; l(1)2; l(1)CRN; l(1)N7; l(1)crn; l30; yok", "protein_names_uniprotkb": "Protein crooked neck", "protein_names_refseq": "CG3193-PA; crn-PA; crooked neck; yolky", "tax_id": 7227, "disease": "basal cell carcinoma (Disease Ontology:DOID:2513)", "pathway": " (dme:Dmel_CG3193); (R-DME-72163)", "pathway_count": 2, "publication_count": 7, "publication_id_list": "10502111;10731132;10731137;12163015;12537569;12537572;2044955", "class_list": "", "function": "May be involved in pre-mRNA splicing process (PubMed:12163015, PubMed:2044955). Involved in embryonic neurogenesis and cell rearrangement during Malpighian tubule morphogenesis (PubMed:10502111, PubMed:2044955)., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "O46071;Q24283", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0016607 nuclear speck;GO:0071013 catalytic step 2 spliceosome;GO:0071011 precatalytic spliceosome", "go_biological_process": "GO:0000398 mRNA splicing, via spliceosome;GO:0000245 spliceosomal complex assembly;GO:0008366 axon ensheathment;GO:0008347 glial cell migration;GO:0000381 regulation of alternative mRNA splicing, via spliceosome", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P17886-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P18091-3", "uniprot_id": "ACTN_DROME", "mass": 106373.0, "length": 917, "protein_name": "Alpha-actinin, sarcomeric", "gene_name": "Actn", "organism": "Fruit fly", "refseq_name": "alpha actinin, isoform D", "refseq_ac": "NP_001188532", "gene_names_uniprotkb": "Actn; CG4376; fliA; l(1)2Cb", "gene_names_refseq": "ACTN; Actn; CG4376; CT14163; CT14232; Dmel\\CG4376; EG:133E12.1; GA17; HM-29; actn; alpha-actinin; alphaActn; fliA; l(1)2Cb; l(1)EA82; y", "protein_names_uniprotkb": "Alpha-actinin, sarcomeric; F-actin cross-linking protein", "protein_names_refseq": "Actn-PD; Alpha-actinin; CG4376-PD; a-actinin; alpha actinin, isoform D; flightless A; flightless-A; lethal(1)2cb", "tax_id": 7227, "disease": "arrhythmogenic right ventricular cardiomyopathy (Disease Ontology:DOID:0050431); congenital myopathy 8 (Disease Ontology:DOID:0081342); dilated cardiomyopathy 1AA (Disease Ontology:DOID:0110428); platelet-type bleeding disorder 15 (Disease Ontology:DOID:0111053); focal segmental glomerulosclerosis 1 (Disease Ontology:DOID:0111128); focal segmental glomerulosclerosis (Disease Ontology:DOID:1312)", "pathway": " (dme:Dmel_CG4376); (R-DME-114608); (R-DME-438066); (R-DME-446388); (R-DME-9013418); (R-DME-9035034)", "pathway_count": 6, "publication_count": 7, "publication_id_list": "10731132;10731137;12537569;12537572;1734023;17353360;2112549", "class_list": "", "function": "F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 6, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "F0JAG6;M9MS06;M9PGA7;O46044;O46045;Q24370;Q8T024;Q9W536;Q9W537", "ec_number_list": "", "go_molecular_function": "GO:0003779 actin binding;GO:0051015 actin filament binding;GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005925 focal adhesion;GO:0030054 cell junction;GO:0030018 Z disc;GO:0030864 cortical actin cytoskeleton", "go_biological_process": "GO:0030036 actin cytoskeleton organization;GO:0051017 actin filament bundle assembly;GO:0045214 sarcomere organization;GO:0055001 muscle cell development", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P18091-3", "record_type": "protein" }, { "uniprot_canonical_ac": "P18106-4", "uniprot_id": "FER_DROME", "mass": 150263.0, "length": 1325, "protein_name": "Tyrosine-protein kinase Fer", "gene_name": "FER", "organism": "Fruit fly", "refseq_name": "FER tyrosine kinase, isoform A", "refseq_ac": "NP_524288", "gene_names_uniprotkb": "FER; CG8874; Fps85D; HD-179; fps", "gene_names_refseq": "CG8874; DFER; DFer; Dfer; Dfps; Dm FPS; DmHD-179; Dmel\\CG8874; FER; FPS; Fer; FpS95D; Fps85D; HD-179; dFer; dfer; dfps 85D; dfps85D; dfps; fer; fps85D; fps", "protein_names_uniprotkb": "Tyrosine-protein kinase Fer; 2.7.10.2", "protein_names_refseq": "CG8874-PA; FER ortholog; FER tyrosine kinase, isoform A; FER-PA; Fps oncogene analog", "tax_id": 7227, "disease": "esophagus squamous cell carcinoma (Disease Ontology:DOID:3748); lung adenocarcinoma (Disease Ontology:DOID:3910); hepatocellular carcinoma (Disease Ontology:DOID:684)", "pathway": " (dme:Dmel_CG8874)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "10731132;12537572;16831834;1898762;9038371;9731193", "class_list": "", "function": "Tyrosine-protein kinase which is required during embryogenesis for formation of the actin cable in leading edge cells of the dorsal epidermis and for the timely progression of dorsal closure. May play a role in regulation of adherens junctions and cell adhesion through phosphorylation of the beta-catenin arm., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q27576;Q86P62;Q8INP1;Q8INP2;Q9TYI1;Q9VHE7;Q9VHE8", "ec_number_list": "2.7.10.1;2.7.10.2;2.7.12.1;2.7.12.2;2.7.11.22;2.7.11.1", "go_molecular_function": "GO:0004713 protein tyrosine kinase activity;GO:0004715 non-membrane spanning protein tyrosine kinase activity;GO:0005524 ATP binding;GO:0005543 phospholipid binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005912 adherens junction;GO:0031234 extrinsic component of cytoplasmic side of plasma membrane", "go_biological_process": "GO:0051017 actin filament bundle assembly;GO:0007411 axon guidance;GO:0007391 dorsal closure;GO:0007394 dorsal closure, elongation of leading edge cells;GO:0046664 dorsal closure, amnioserosa morphology change", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P18106-4", "record_type": "protein" }, { "uniprot_canonical_ac": "P18167-1", "uniprot_id": "ESTP_DROME", "mass": 61054.0, "length": 544, "protein_name": "Esterase P", "gene_name": "Est-P", "organism": "Fruit fly", "refseq_name": "esterase P", "refseq_ac": "NP_788501", "gene_names_uniprotkb": "Est-P; CG17148; EstP", "gene_names_refseq": "CG17148; Dmel\\CG17148; EST-5; EST7; ESTP; Est-5; Est-7; Est-P; Est7; EstP; PsiEst-6; est-P; psiEst-6; yEst-6; yEst6", "protein_names_uniprotkb": "Esterase P; 3.1.1.1; Carboxylesterase-P; Carboxylic-ester hydrolase P; Est-P", "protein_names_refseq": "CG17148-PA; Est-P-PA; esterase P", "tax_id": 7227, "disease": "alcohol dependence (Disease Ontology:DOID:0050741); stroke (Disease Ontology:DOID:0051061); Hirschsprung's disease (Disease Ontology:DOID:10487); stomach cancer (Disease Ontology:DOID:10534); Alzheimer's disease (Disease Ontology:DOID:10652); Huntington's disease (Disease Ontology:DOID:12858); Parkinson's disease (Disease Ontology:DOID:14330); epilepsy (Disease Ontology:DOID:1826); cannabis dependence (Disease Ontology:DOID:1849); multiple sclerosis (Disease Ontology:DOID:2377); gastrointestinal system cancer (Disease Ontology:DOID:3119); liver cancer (Disease Ontology:DOID:3571); myasthenia gravis (Disease Ontology:DOID:437); hepatocellular carcinoma (Disease Ontology:DOID:684); subacute delirium (Disease Ontology:DOID:8645); colorectal cancer (Disease Ontology:DOID:9256); bacterial meningitis (Disease Ontology:DOID:9470); type 1 diabetes mellitus (Disease Ontology:DOID:9744); drug dependence (Disease Ontology:DOID:9974); heroin dependence (Disease Ontology:DOID:9976)", "pathway": " (dme:Dmel_CG17148)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "10731132;12537572;2105433", "class_list": "", "function": "", "predicted_glycosites": 4, "predicted_n_glycosites": 4, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 20, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "Q32KD6;Q9VTV0", "ec_number_list": "3.1.1.1", "go_molecular_function": "GO:0017171 serine hydrolase activity;GO:0106435 carboxylesterase activity", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "P18167-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P18486-1", "uniprot_id": "DHAPP_DROME", "mass": 57021.0, "length": 510, "protein_name": "3,4-dihydroxyphenylacetaldehyde synthase", "gene_name": "amd", "organism": "Fruit fly", "refseq_name": "alpha methyl dopa-resistant, isoform A", "refseq_ac": "NP_476592", "gene_names_uniprotkb": "amd; CG10501; l(2)amd", "gene_names_refseq": "AMD-r; CG10501; CG17345; Dmel\\CG10501; X04695; amd; fAMD; l(2)37Bk; l(2)amd alpha-methyldopa hypersensitive; l(2)amd[H]; l(2)amd", "protein_names_uniprotkb": "3,4-dihydroxyphenylacetaldehyde synthase; 4.1.1.107; AMD-r protein; Alpha-methyldopa resistant protein; DHPAA synthase; DOPAL synthase", "protein_names_refseq": "3,4-dihydroxyphenylacetaldehyde synthase; CG10501-PA; DHPA synthase; DHPAA synthase; alpha methyl dopa-resistant, isoform A; alpha methyl dopa; alpha-methotrexate deficient; alpha-methyl dopa resistant; amd-PA; dopa decarboxylase; transcription unit No. 1", "tax_id": 7227, "disease": "nicotine dependence (Disease Ontology:DOID:0050742); aromatic L-amino acid decarboxylase deficiency (Disease Ontology:DOID:0090123); portal hypertension (Disease Ontology:DOID:10762); nephrotic syndrome (Disease Ontology:DOID:1184); Parkinson's disease (Disease Ontology:DOID:14330); hyperinsulinism (Disease Ontology:DOID:2018); bipolar disorder (Disease Ontology:DOID:3312); inherited metabolic disorder (Disease Ontology:DOID:655); end stage renal disease (Disease Ontology:DOID:783)", "pathway": " (dme:Dmel_CG10501)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "10731132;12537572;21283636;29037755;29155013;3021571;7729591", "class_list": "", "function": "Catalyzes the decarboxylation-oxidative deamination of L-3,4-dihydroxyphenylalanine (L-DOPA) to 3,4-dihydroxylphenylacetaldehyde (DHPAA) (PubMed:21283636). Involved in cuticle development (Probable). Probably responsible for the protein cross-linking during the development of flexible cuticles (PubMed:21283636)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 9, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9VIZ8;Q9VIZ9", "ec_number_list": "4.1.1.107", "go_molecular_function": "GO:0030170 pyridoxal phosphate binding;GO:0004058 aromatic-L-amino-acid decarboxylase activity;GO:0016831 carboxy-lyase activity;GO:0042302 structural constituent of cuticle;GO:0106425 3,4-dihydroxyphenylacetaldehyde synthase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0042335 cuticle development;GO:0006584 catecholamine metabolic process;GO:0006520 amino acid metabolic process;GO:0019752 carboxylic acid metabolic process;GO:0040003 chitin-based cuticle development", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P18486-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P18488-1", "uniprot_id": "EMS_DROME", "mass": 53391.0, "length": 494, "protein_name": "Homeotic protein empty spiracles", "gene_name": "ems", "organism": "Fruit fly", "refseq_name": "empty spiracles", "refseq_ac": "NP_731868", "gene_names_uniprotkb": "ems; CG2988; E4", "gene_names_refseq": "CG2988; Dmel\\CG2988; E4; EMS; Ems; W13; ant; ems", "protein_names_uniprotkb": "Homeotic protein empty spiracles", "protein_names_refseq": "CG2988-PA; antenna; empty spiracles; empty spiracle; empty-spiracles; ems-PA", "tax_id": 7227, "disease": "colorectal adenocarcinoma (Disease Ontology:DOID:0050861); stomach cancer (Disease Ontology:DOID:10534); lung squamous cell carcinoma (Disease Ontology:DOID:3907); lung adenocarcinoma (Disease Ontology:DOID:3910); esophagus adenocarcinoma (Disease Ontology:DOID:4914); malignant pleural mesothelioma (Disease Ontology:DOID:7474); colorectal cancer (Disease Ontology:DOID:9256)", "pathway": " (dme:Dmel_CG2988)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "10731132;12537572;1376248;2576012", "class_list": "", "function": "Acts as a homeotic selector gene controlling antennal and mandibular segment identity., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 7, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q5BIB4;Q9VFQ1", "ec_number_list": "", "go_molecular_function": "GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0007409 axonogenesis;GO:0030154 cell differentiation;GO:0007420 brain development;GO:0048813 dendrite morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P18488-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P19107-1", "uniprot_id": "ARRB_DROME", "mass": 45029.0, "length": 401, "protein_name": "Phosrestin-1", "gene_name": "Arr2", "organism": "Fruit fly", "refseq_name": "arrestin 2", "refseq_ac": "NP_523976", "gene_names_uniprotkb": "Arr2; ArrB; CG5962", "gene_names_refseq": "49; AH; ARR2; Arr-2; Arr2; ArrB-ml; ArrB; Arr; Beta-Arrestin; CG5962; DAII; DmArrestin-2; Dmel\\CG5962; Dro.-Arr.II; PRI; arr2; arr", "protein_names_uniprotkb": "Phosrestin-1; 49 kDa arrestin-like protein; Arrestin-2; Arrestin-B; Phosrestin I", "protein_names_refseq": "49kD arrestin homolog; Arr2-PA; Arrestin-2; Beta-Arrestin; CG5962-PA; arrestin 2; arrestin B; arrestin-like protein; arrestin2; phosrestin I; phosrestin-1", "tax_id": 7227, "disease": "alcohol dependence (Disease Ontology:DOID:0050741); sensorineural hearing loss (Disease Ontology:DOID:10003); portal hypertension (Disease Ontology:DOID:10762); hypertension (Disease Ontology:DOID:10763); major depressive disorder (Disease Ontology:DOID:1470); drug psychosis (Disease Ontology:DOID:1742); brain infarction (Disease Ontology:DOID:3454); hepatocellular carcinoma (Disease Ontology:DOID:684); type 2 diabetes mellitus (Disease Ontology:DOID:9352)", "pathway": " (dme:Dmel_CG5962); (R-DME-418555); (R-DME-432720); (R-DME-432722); (R-DME-5674135); (R-DME-5689880); (R-DME-8856825); (R-DME-8856828); (R-DME-9839389)", "pathway_count": 9, "publication_count": 7, "publication_id_list": "10731132;12537572;1905538;2158671;36994075;8185954;8316831", "class_list": "", "function": "Regulates photoreceptor cell deactivation (PubMed:36994075, PubMed:8316831). Arr1 and Arr2 proteins are mediators of rhodopsin inactivation and are essential for the termination of the phototransduction cascade (PubMed:8316831). Involved in regulating normal cycles of per nuclear accumulation in brain circadian neurons and thus is important for normal circadian behavior (PubMed:36994075). In the dark, functions with Arr1 to promote the formation of cytosolic Bdbt foci, which are required for dco localization to photoreceptor nuclei where it phosphorylates and activates degradation of per (PubMed:36994075)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 9, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q9VSN6", "ec_number_list": "", "go_molecular_function": "GO:0001664 G protein-coupled receptor binding;GO:0002046 opsin binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0016028 rhabdomere;GO:0016029 subrhabdomeral cisterna", "go_biological_process": "GO:0007165 signal transduction;GO:0007600 sensory perception;GO:0007601 visual perception;GO:0045494 photoreceptor cell maintenance;GO:0002031 G protein-coupled receptor internalization", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P19107-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P20009-1", "uniprot_id": "DLL_DROME", "mass": 35262.0, "length": 327, "protein_name": "Homeotic protein distal-less", "gene_name": "Dll", "organism": "Fruit fly", "refseq_name": "Distal-less, isoform A", "refseq_ac": "NP_523857", "gene_names_uniprotkb": "Dll; BR; Ba; CG3629", "gene_names_refseq": "2.7; Art; Ba; BcDNA:LP01770; CG3629; DLL; Dll; Dmel\\CG3629; E(Arp); En(Arp); dll; l(2)01092; l(2)387", "protein_names_uniprotkb": "Homeotic protein distal-less; Protein brista", "protein_names_refseq": "CG3629-PA; Distal-less, isoform A; Distall-less; Dll-PA; brista; distal-less; distalless; distallless; enhancer of Arp", "tax_id": 7227, "disease": "orofacial cleft 15 (Disease Ontology:DOID:0080408); split hand-foot malformation 1 (Disease Ontology:DOID:0090021); split hand-foot malformation 1 with sensorineural hearing loss (Disease Ontology:DOID:0090024); amelogenesis imperfecta type 4 (Disease Ontology:DOID:0110053); trichodontoosseous syndrome (Disease Ontology:DOID:0111565)", "pathway": " (dme:Dmel_CG3629)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "10731132;12537569;12537572;1358457;2564639;9303541;9778507", "class_list": "", "function": "Transcription factor that plays a role in larval and adult appendage development. Specifies the identity of ventral appendages (including legs and antennae) and suppresses dorsal appendage development. Involved in patterning the distal-proximal limb axis. May control the adhesive properties of cells during limb morphogenesis. Also has a secondary role in the normal patterning of the wing margin., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "Q7KVF4;Q8MZ41;Q9W0Z8;Q9W0Z9", "ec_number_list": "", "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0010092 specification of animal organ identity;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0010629 negative regulation of gene expression;GO:0030154 cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P20009-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P20348-1", "uniprot_id": "JANA_DROME", "mass": 15220.0, "length": 135, "protein_name": "Sex-regulated protein janus-A", "gene_name": "janA", "organism": "Fruit fly", "refseq_name": "janus A, isoform B", "refseq_ac": "NP_788762", "gene_names_uniprotkb": "janA; CG7933", "gene_names_refseq": "BcDNA:AT12574; CG7933; Dmel\\CG7933; Jan; Y; jan A; janA; janus; jan", "protein_names_uniprotkb": "Sex-regulated protein janus-A", "protein_names_refseq": "CG7933-PB; janA-PB; janus A, isoform B; janus", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG7933)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "10731132;12537569;12537572;2503707", "class_list": "", "function": "JanA and janB regulate somatic sex differentiation., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A4V3M6;Q8T475;Q9VAB6", "ec_number_list": "", "go_molecular_function": "GO:0101006 protein histidine phosphatase activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0030154 cell differentiation;GO:0007548 sex differentiation", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P20348-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P20439-1", "uniprot_id": "CCNB_DROME", "mass": 59256.0, "length": 530, "protein_name": "G2/mitotic-specific cyclin-B", "gene_name": "CycB", "organism": "Fruit fly", "refseq_name": "cyclin B, isoform A", "refseq_ac": "NP_726244", "gene_names_uniprotkb": "CycB; CG3510", "gene_names_refseq": "2g; 3510; CG3510; CYC-B; CYCB; CYCLIN B; Cyc B; CycB; Cycb; Cyclin B1; DmcycB; Dmel\\CG3510; chr2R:18312808..18312907; cyc B; cyc-B; cycB; cycb; cyclin B; cyclinB1; cyclinB; mAbF2F4", "protein_names_uniprotkb": "G2/mitotic-specific cyclin-B", "protein_names_refseq": "CG3510-PA; CycB PRE/TRE element; CycB-PA; Cyclin-B; cyclin B, isoform A; cyclin B1; cyclinB; dCyclinB", "tax_id": 7227, "disease": "prostate cancer (Disease Ontology:DOID:10283); breast cancer (Disease Ontology:DOID:1612); ovary epithelial cancer (Disease Ontology:DOID:2152); prostate adenocarcinoma (Disease Ontology:DOID:2526); endometrial carcinoma (Disease Ontology:DOID:2871); cervical cancer (Disease Ontology:DOID:4362); renal cell carcinoma (Disease Ontology:DOID:4450); in situ carcinoma (Disease Ontology:DOID:8719)", "pathway": " (dme:Dmel_CG3510); (R-DME-174048); (R-DME-176408); (R-DME-176412); (R-DME-176417); (R-DME-2500257); (R-DME-2565942); (R-DME-2995383); (R-DME-3301854); (R-DME-4419969); (R-DME-6804114); (R-DME-68875); (R-DME-69273); (R-DME-69478); (R-DME-75035); (R-DME-8878166)", "pathway_count": 16, "publication_count": 9, "publication_id_list": "10731132;12537569;12537572;1451670;17372656;18327897;2139805;2142452;2564167", "class_list": "", "function": "Essential for the control of the cell cycle at the G2/M (mitosis) transition., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 8, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q0E8Y2;Q8MME2;Q9I7V2;Q9TYH6;Q9TYH7;Q9V3F4", "ec_number_list": "", "go_molecular_function": "GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0051233 spindle midzone;GO:0000775 chromosome, centromeric region;GO:0005815 microtubule organizing center", "go_biological_process": "GO:0007079 mitotic chromosome movement towards spindle pole;GO:0008608 attachment of spindle microtubules to kinetochore;GO:0000086 G2/M transition of mitotic cell cycle;GO:0000082 G1/S transition of mitotic cell cycle;GO:0000281 mitotic cytokinesis", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P20439-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P20477-1", "uniprot_id": "GLNA1_DROME", "mass": 44396.0, "length": 399, "protein_name": "Glutamine synthetase 1, mitochondrial", "gene_name": "Gs1", "organism": "Fruit fly", "refseq_name": "glutamine synthetase 1, isoform D", "refseq_ac": "NP_001162839", "gene_names_uniprotkb": "Gs1; CG2718", "gene_names_refseq": "CG2718; Dmel\\CG2718; GS1; GSI; Gs1; GsI; fs(2)P52; fs(2)throng; gs-m; gsI; l(2)21Bc; mt-gs; thg", "protein_names_uniprotkb": "Glutamine synthetase 1, mitochondrial; 6.3.1.2; GS-m; Glutamate--ammonia ligase 1", "protein_names_refseq": "CG2718-PD; Glutamate-ammonia ligase; Gs1-PD; glutamine synthase 1; glutamine synthetase 1, isoform D; glutamine synthetase 1; glutamine synthetase I; glutamine synthetase-1; mitochondrial glutamine synthetase; throng", "tax_id": 7227, "disease": "congenital glutamine deficiency (Disease Ontology:DOID:0070544); developmental and epileptic encephalopathy 116 (Disease Ontology:DOID:0070545); Alzheimer's disease (Disease Ontology:DOID:10652); primary open angle glaucoma (Disease Ontology:DOID:1070); heart disease (Disease Ontology:DOID:114); Huntington's disease (Disease Ontology:DOID:12858); epilepsy (Disease Ontology:DOID:1826); transient cerebral ischemia (Disease Ontology:DOID:224); temporal lobe epilepsy (Disease Ontology:DOID:3328); middle cerebral artery infarction (Disease Ontology:DOID:3525); liver disease (Disease Ontology:DOID:409); liver cirrhosis (Disease Ontology:DOID:5082); schizophrenia (Disease Ontology:DOID:5419); diabetic retinopathy (Disease Ontology:DOID:8947); obesity (Disease Ontology:DOID:9970)", "pathway": " (dme:Dmel_CG2718); (R-DME-210455); (R-DME-8964539)", "pathway_count": 3, "publication_count": 11, "publication_id_list": "10731132;12537569;12537572;1969491;19755423;2897195;2907404;31941072;6190476;7896146;8937983", "class_list": "", "function": "Glutamine synthetase, a component of the Glutamate-Glutamine Cycle (GGC) (PubMed:31941072). May also indirectly stimulate production of asparagine from aspartic acid (PubMed:31941072). May be involved in glutamine induced megamitochondrial formation in response to stress conditions (PubMed:19755423). Promotes cell survival by promoting autophagy (PubMed:31941072). Plays an essential role during embryogenesis, probably as a source of L-glutamine for downstream biosynthetic pathways (PubMed:8937983)., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 15, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A4UZX3;E1JHQ1;O96770;Q9VPK0", "ec_number_list": "6.3.1.2", "go_molecular_function": "GO:0005524 ATP binding;GO:0004356 glutamine synthetase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion", "go_biological_process": "GO:0006909 phagocytosis;GO:0006542 glutamine biosynthetic process;GO:1901704 L-glutamine biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "P20477-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P22465-1", "uniprot_id": "ANX10_DROME", "mass": 35706.0, "length": 321, "protein_name": "Annexin B10", "gene_name": "AnxB10", "organism": "Fruit fly", "refseq_name": "annexin B10, isoform B", "refseq_ac": "NP_001162804", "gene_names_uniprotkb": "AnxB10; AnnX; CG9579", "gene_names_refseq": "ANXB10; AnnB10; AnnX; Annx; Ann; AnxB10; CG9579; Dmel\\CG9579; annexin; anxX", "protein_names_uniprotkb": "Annexin B10; Annexin X; Annexin-10", "protein_names_refseq": "AnxB10-PB; CG9579-PB; annexin B10, isoform B; annexin X; dAnnexin X", "tax_id": 7227, "disease": "cryptorchidism (Disease Ontology:DOID:11383); hypothyroidism (Disease Ontology:DOID:1459); glomerulonephritis (Disease Ontology:DOID:2921); pancreatic ductal carcinoma (Disease Ontology:DOID:3587); cholangiocarcinoma (Disease Ontology:DOID:4947); myocardial infarction (Disease Ontology:DOID:5844); hepatocellular carcinoma (Disease Ontology:DOID:684); hyperthyroidism (Disease Ontology:DOID:7998); Wilson disease (Disease Ontology:DOID:893)", "pathway": " (dme:Dmel_CG9579); (R-DME-114608); (R-DME-6798695); (R-DME-9860927)", "pathway_count": 4, "publication_count": 6, "publication_id_list": "10731132;12537569;12537572;15952742;2141610;7710691", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 9, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "E1JJR8;E8NH50;Q27586;Q9W5W5", "ec_number_list": "", "go_molecular_function": "GO:0005509 calcium ion binding;GO:0005544 calcium-dependent phospholipid binding;GO:0001786 phosphatidylserine binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0016020 membrane;GO:0012506 vesicle membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P22465-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P22469-1", "uniprot_id": "Z600_DROME", "mass": 10530.0, "length": 90, "protein_name": "Protein Z600", "gene_name": "Z600", "organism": "Fruit fly", "refseq_name": "Z600", "refseq_ac": "NP_524083", "gene_names_uniprotkb": "Z600; CG17962; frs", "gene_names_refseq": "3.2; CG17962; DMZ60MEX; Dmel\\CG17962; Frs; Z600; frs; z600", "protein_names_uniprotkb": "Protein Z600; Protein Fruhstart", "protein_names_refseq": "CG17962-PA; Z600-PA; Z600; fruhstart; frustart", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG17962)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "10731132;10850494;12537572;12919679;17431409;18327897;2125289;2478402;2497054", "class_list": "", "function": "Cell cycle regulator that is involved in modulating and adjusting cell proliferation according to the requirements of the developmental program (PubMed:10850494, PubMed:12919679, PubMed:17431409). Interacts with mitotic Cdk1-cyclin complexes to inhibit mitotic entry at the G2/M transition (PubMed:17431409). Likely to function by binding to the hydrophobic patch of cyclins to interfere with the interaction between the complex and certain Cdk1 substrates (PubMed:17431409). At the mid-blastula transition, involved in the cell cycle arrest in G2 of cycle 14 by delaying mitosis and thus reducing cell proliferation allowing cell fate specification and morphogenesis to take place (PubMed:12919679). Acts downstream or in parallel to the checkpoint regulator grp which is also required for the cell cycle pause at cycle 14 (PubMed:12919679). During gastrulation, delays mitosis in the ventral region of the embryonic mesoderm thus allowing invagination to be completed before cell division takes place (PubMed:10850494, PubMed:12919679, PubMed:17431409)., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0JQ32;Q4V3M0;Q9VUP1", "ec_number_list": "", "go_molecular_function": "GO:0030332 cyclin binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0051301 cell division;GO:0045839 negative regulation of mitotic nuclear division;GO:0007369 gastrulation;GO:0010972 negative regulation of G2/M transition of mitotic cell cycle;GO:0007370 ventral furrow formation", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P22469-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P22809-1", "uniprot_id": "BAGP_DROME", "mass": 41993.0, "length": 382, "protein_name": "Homeobox protein bagpipe", "gene_name": "bap", "organism": "Fruit fly", "refseq_name": "bagpipe", "refseq_ac": "NP_732637", "gene_names_uniprotkb": "bap; CG7902; NK3; bgp", "gene_names_refseq": "BAP; Bag; Bap1; Bap; CG7902; Dmel\\CG7902; NK-3; NK3; Nkx3.2; bag; bap; bgp; dNK-3; nk-3", "protein_names_uniprotkb": "Homeobox protein bagpipe; Homeobox protein NK-3", "protein_names_refseq": "CG7902-PA; bagpipe; bap-PA", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG7902)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "10731132;12537572;15126403;2573058;7774017;8101173", "class_list": "", "function": "Involved in the determination of cell fates in the dorsal mesoderm., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q24254;Q6UJA4;Q6UJA5;Q6UJA8;Q6UJA9;Q6UJB1;Q6UJB2;Q9VDA6", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0043565 sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0001710 mesodermal cell fate commitment;GO:0006357 regulation of transcription by RNA polymerase II;GO:0030154 cell differentiation;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0007498 mesoderm development", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P22809-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P22815-1", "uniprot_id": "BOSS_DROME", "mass": 99950.0, "length": 896, "protein_name": "Protein bride of sevenless", "gene_name": "boss", "organism": "Fruit fly", "refseq_name": "bride of sevenless", "refseq_ac": "NP_542440", "gene_names_uniprotkb": "boss; CG8285", "gene_names_refseq": "BOSS; Boss; Bos; CG8285; Dmel\\CG8285; F; X55887; boss", "protein_names_uniprotkb": "Protein bride of sevenless", "protein_names_refseq": "CG8285-PA; F transcript; boss-PA; bride of sevenless", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG8285)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "10731132;12537572;1857416;2276620;24554766", "class_list": "", "function": "Acts as a ligand for sevenless tyrosine-kinase receptor during eye development., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 3, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 3, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 3, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "Q9VBJ5", "ec_number_list": "", "go_molecular_function": "GO:0005118 sevenless binding;GO:0001640 adenylate cyclase inhibiting G protein-coupled glutamate receptor activity;GO:0048018 receptor ligand activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0035997 rhabdomere microvillus membrane", "go_biological_process": "GO:0055088 lipid homeostasis;GO:0007601 visual perception;GO:0042593 glucose homeostasis;GO:0009749 response to glucose;GO:0007465 R7 cell fate commitment", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P22815-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P22817-1", "uniprot_id": "IDE_DROME", "mass": 113684.0, "length": 990, "protein_name": "Insulin-degrading enzyme", "gene_name": "Ide", "organism": "Fruit fly", "refseq_name": "insulin degrading metalloproteinase", "refseq_ac": "NP_524182", "gene_names_uniprotkb": "Ide; CG5517", "gene_names_refseq": "CG5517; Dmel\\CG5517; IDE; Ide; dIDE; dIde; dide; dlde; ide", "protein_names_uniprotkb": "Insulin-degrading enzyme; 3.4.24.56; Insulin protease; Insulinase; Insulysin", "protein_names_refseq": "CG5517-PB; Ide-PB; insulin degrading enzyme; insulin degrading metalloproteinase; insulin-degrading enzyme", "tax_id": 7227, "disease": "diabetic encephalopathy (Disease Ontology:DOID:0050850); metabolic dysfunction-associated steatotic liver disease (Disease Ontology:DOID:0080208); Alzheimer's disease (Disease Ontology:DOID:10652); type 2 diabetes mellitus (Disease Ontology:DOID:9352)", "pathway": " (dme:Dmel_CG5517); (R-DME-5689880); (R-DME-9033241)", "pathway_count": 3, "publication_count": 5, "publication_id_list": "10731132;12537569;12537572;2126597;3139025", "class_list": "", "function": "Can cleave insulin and TGF-alpha., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "B9EQR9;Q86MR2;Q95S06;Q9VPG8", "ec_number_list": "2.3.1.42;1.1.3.15;1.1.1.42;6.2.1.3;3.1.1.29;1.11.1.6;3.4.24.56;1.14.13.39;1.3.3.6;3.6.5.-;2.3.-.-;2.3.1.137;2.3.1.7;5.1.99.4;2.3.1.176;2.3.1.16;2.3.1.155;4.1.3.4;1.4.3.3;1.-.-.-;1.1.1.184;2.3.2.27;5.3.3.8;3.4.21.-;2.6.1.44;3.4.19.12;5.3.3.21", "go_molecular_function": "GO:0004222 metalloendopeptidase activity;GO:0008237 metallopeptidase activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005777 peroxisome;GO:0005829 cytosol;GO:0005886 plasma membrane", "go_biological_process": "GO:0046627 negative regulation of insulin receptor signaling pathway;GO:0006508 proteolysis;GO:0050829 defense response to Gram-negative bacterium;GO:0043171 peptide catabolic process;GO:0051603 proteolysis involved in protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P22817-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P22979-1", "uniprot_id": "HSP6C_DROME", "mass": 22180.0, "length": 199, "protein_name": "Heat shock protein 67B3", "gene_name": "Hsp67Bc", "organism": "Fruit fly", "refseq_name": "heat shock gene 67Bc", "refseq_ac": "NP_523994", "gene_names_uniprotkb": "Hsp67Bc; CG4190", "gene_names_refseq": "CG4190; Dm-HSP67Bc; Dmel18.0; Dmel\\CG4190; HSP67BC; HSP67Bc; HSP67; HSPB8; Hsp-G3; Hsp67BC; Hsp67Bc; HspB8; Hspg3; gene 3; gene-3; gene3; gene5; hsp67Bc; hsp67B; hsp67bc; small hsp locus 67B", "protein_names_uniprotkb": "Heat shock protein 67B3; Heat shock 18 kDa protein", "protein_names_refseq": "CG4190-PA; Hsp67Bc-PA; gene 3; heat shock gene 67Bc", "tax_id": 7227, "disease": "adult-onset myofibrillar myopathy 2A (Disease Ontology:DOID:0080093); infantile-onset myofibrillar myopathy-2B (Disease Ontology:DOID:0080309); Charcot-Marie-Tooth disease axonal type 2L (Disease Ontology:DOID:0110174); cataract 16 multiple types (Disease Ontology:DOID:0110250); cataract 9 multiple types (Disease Ontology:DOID:0110266); dilated cardiomyopathy 1II (Disease Ontology:DOID:0110450); autosomal dominant distal hereditary motor neuronopathy 2 (Disease Ontology:DOID:0111206); macular degeneration (Disease Ontology:DOID:4448); cataract (Disease Ontology:DOID:83); ocular hypertension (Disease Ontology:DOID:9282); galactosemia (Disease Ontology:DOID:9870)", "pathway": " (dme:Dmel_CG4190); (R-DME-3371571)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "10731132;12537572;3123699", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 11, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q4V3R7;Q9VSW9", "ec_number_list": "", "go_molecular_function": "GO:0051082 unfolded protein binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0010506 regulation of autophagy;GO:0006457 protein folding;GO:0006446 regulation of translational initiation;GO:0009408 response to heat;GO:0042026 protein refolding", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "P22979-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P23572-1", "uniprot_id": "CDK1_DROME", "mass": 34439.0, "length": 297, "protein_name": "Cyclin-dependent kinase 1", "gene_name": "Cdk1", "organism": "Fruit fly", "refseq_name": "Cyclin-dependent kinase 1", "refseq_ac": "NP_476797", "gene_names_uniprotkb": "Cdk1; CG5363; cdc2", "gene_names_refseq": "5363; CDC2; CDCDm; CDK1/CDC2; CDK1; CG5363; Cdc2; Cdk-1; Cdk1; Dcdc2; Dm cdc2; DmCdc2; DmCdk1; Dmcdc2; Dmel\\CG5363; cdc2Dm; cdc2; cdc; cdk1; dCdk1; group 4; l(2)31Eh", "protein_names_uniprotkb": "Cyclin-dependent kinase 1; 2.7.11.22; 2.7.11.23; CDK1; Cell division control protein 2 homolog; Cell division protein kinase 1; p34 protein kinase", "protein_names_refseq": "CG5363-PA; Cdk1-PA; Cyclin-dependent kinase 1; cdc2 kinase; cell division control; cyclin dependent kinase; cyclin-dependent kinase; protein 2", "tax_id": 7227, "disease": "urinary bladder cancer (Disease Ontology:DOID:11054); breast cancer (Disease Ontology:DOID:1612); cancer (Disease Ontology:DOID:162); transitional cell carcinoma (Disease Ontology:DOID:2671); gallbladder adenocarcinoma (Disease Ontology:DOID:3500); cervical cancer (Disease Ontology:DOID:4362); hepatocellular carcinoma (Disease Ontology:DOID:684)", "pathway": " (dme:Dmel_CG5363); (R-DME-110056); (R-DME-174048); (R-DME-174184); (R-DME-176408); (R-DME-176412); (R-DME-176417); (R-DME-2500257); (R-DME-2565942); (R-DME-2995383); (R-DME-3301854); (R-DME-4419969); (R-DME-6804114); (R-DME-68875); (R-DME-69273); (R-DME-69478); (R-DME-75035); (R-DME-8878166); (R-DME-9833482)", "pathway_count": 19, "publication_count": 21, "publication_id_list": "10731132;11882391;12537569;12537572;15581871;15589158;15591787;16951084;17431409;18327897;18824564;2120044;2120045;23316440;24214341;27170181;29167465;29746464;31979075;8223248;8405984", "class_list": "", "function": "Plays a key role in the control of the eukaryotic cell cycle (PubMed:15581871, PubMed:2120044). Required for entry into S-phase and mitosis (PubMed:15581871, PubMed:2120044, PubMed:29746464). In embryos, promotes the release of Rif1 from chromatin during mid-blastula transition (PubMed:29746464). p34 is a component of the kinase complex that phosphorylates the repetitive C-terminus of RNA polymerase II (PubMed:2120044)., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 7, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 7, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0ANT1;Q86FT5;Q86FT6;Q86FT7;Q86FT8;Q86FT9;Q9TX68;Q9TX69;Q9TX70;Q9TX71;Q9TX72;Q9TX73;Q9TX74;Q9VKX5", "ec_number_list": "2.3.2.-;2.7.11.17;2.7.11.1;2.7.11.13;2.7.11.24;2.7.11.22;2.7.11.21;5.6.1.8;2.7.11.11;3.1.3.48;2.7.11.23;2.3.2.23;2.7.12.1;2.7.10.2;2.7.11.25;2.7.11.12;2.7.12.2;3.4.19.-;5.6.1.5;3.4.21.-;2.3.2.24;2.7.11.39", "go_molecular_function": "GO:0004672 protein kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0004693 cyclin-dependent protein serine/threonine kinase activity;GO:0008353 RNA polymerase II CTD heptapeptide repeat kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0000307 cyclin-dependent protein kinase holoenzyme complex;GO:0045169 fusome", "go_biological_process": "GO:0030174 regulation of DNA-templated DNA replication initiation;GO:0000086 G2/M transition of mitotic cell cycle;GO:0032880 regulation of protein localization;GO:0000082 G1/S transition of mitotic cell cycle;GO:0007140 male meiotic nuclear division", "synthesized_glycan_count": 0, "hit_score": 2.2, "record_id": "P23572-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P23779-1", "uniprot_id": "CYTL_DROME", "mass": 13437.0, "length": 126, "protein_name": "Cystatin-like protein", "gene_name": "Cys", "organism": "Fruit fly", "refseq_name": "Cystatin-like", "refseq_ac": "NP_476856", "gene_names_uniprotkb": "Cys; CG8050", "gene_names_refseq": "BcDNA:RH72992; CG8050; Cys; Dmel\\CG8050; anon-EST:Liang-2.34; clone 2.34; cys", "protein_names_uniprotkb": "Cystatin-like protein", "protein_names_refseq": "CG8050-PA; Cys-PA; Cystatin-like; cystatin", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG8050)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "10731132;12537569;12537572;1701398", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q8SZN3;Q9VFI2", "ec_number_list": "", "go_molecular_function": "GO:0004869 cysteine-type endopeptidase inhibitor activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0007320 insemination", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P23779-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P25028-1", "uniprot_id": "FSYA_DROME", "mass": 77726.0, "length": 696, "protein_name": "Mitosis initiation protein fs(1)Ya", "gene_name": "fs(1)Ya", "organism": "Fruit fly", "refseq_name": "female sterile (1) young arrest", "refseq_ac": "NP_477493", "gene_names_uniprotkb": "fs(1)Ya; CG2707", "gene_names_refseq": "CG2707; Dmel\\CG2707; EG:95B7.4; YA; Ya; fs(1)73; fs(1)M12; fs(1)Y2; fs(1)Y[a]; fs(1)Ya", "protein_names_uniprotkb": "Mitosis initiation protein fs(1)Ya", "protein_names_refseq": "CG2707-PA; female sterile (1) young arrest; fs(1)Ya-PA; young arrest", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG2707)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "10731132;10731137;12537569;12537572;18327897;1986869", "class_list": "", "function": "Cell cycle-dependent nuclear envelope component required for embryonic mitosis., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q8T057;Q9W4W0;Q9W4W1", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005635 nuclear envelope;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005652 nuclear lamina", "go_biological_process": "GO:0000278 mitotic cell cycle;GO:0051301 cell division;GO:0006260 DNA replication;GO:0006325 chromatin organization;GO:0030261 chromosome condensation", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P25028-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P25162-1", "uniprot_id": "ACH4_DROME", "mass": 60140.0, "length": 519, "protein_name": "Acetylcholine receptor subunit beta-like 2", "gene_name": "nAChRbeta2", "organism": "Fruit fly", "refseq_name": "nicotinic acetylcholine receptor beta2, isoform A", "refseq_ac": "NP_524483", "gene_names_uniprotkb": "nAChRbeta2; Acr96Ac; AcrF; CG6798; SBD; nAcRbeta-96", "gene_names_refseq": "Acr96Ac; AcrF; CG6798; Dbeta2; Dmel\\CG6798; EMS2; SBD; beta2; beta[[2]]; nACR beta 96A; nACRbeta; nAChR-beta96A; nAChRbeta2; nAChR; nAcRbeta-96A; nAcRbeta; nAcRs; nAcr96Ac; sbd", "protein_names_uniprotkb": "Acetylcholine receptor subunit beta-like 2; Nicotinic acetylcholine receptor beta 2", "protein_names_refseq": "CG6798-PA; Dbeta2; SBD; nAChRbeta2-PA; nicotinic acetylcholine receptor beta 96A; nicotinic acetylcholine receptor beta2, isoform A; nicotinic acetylcholine receptor beta2; second beta-like subunit of drosophila", "tax_id": 7227, "disease": "alcohol dependence (Disease Ontology:DOID:0050741); nicotine dependence (Disease Ontology:DOID:0050742); autosomal dominant nocturnal frontal lobe epilepsy 4 (Disease Ontology:DOID:0060685); congenital myasthenic syndrome 4A (Disease Ontology:DOID:0110678); congenital myasthenic syndrome 4C (Disease Ontology:DOID:0110679); lung cancer (Disease Ontology:DOID:1324); Parkinson's disease (Disease Ontology:DOID:14330); major depressive disorder (Disease Ontology:DOID:1470); alcohol use disorder (Disease Ontology:DOID:1574); depressive disorder (Disease Ontology:DOID:1596); asthma (Disease Ontology:DOID:2841); chronic obstructive pulmonary disease (Disease Ontology:DOID:3083); bipolar disorder (Disease Ontology:DOID:3312); congenital myasthenic syndrome (Disease Ontology:DOID:3635); esophagus squamous cell carcinoma (Disease Ontology:DOID:3748); lung squamous cell carcinoma (Disease Ontology:DOID:3907); lung non-small cell carcinoma (Disease Ontology:DOID:3908); lung adenocarcinoma (Disease Ontology:DOID:3910); lung large cell carcinoma (Disease Ontology:DOID:4556); lung small cell carcinoma (Disease Ontology:DOID:5409); cocaine abuse (Disease Ontology:DOID:809); nasopharynx carcinoma (Disease Ontology:DOID:9261); cocaine dependence (Disease Ontology:DOID:9975)", "pathway": " (dme:Dmel_CG6798); (R-DME-629587); (R-DME-629594); (R-DME-629597); (R-DME-6798695)", "pathway_count": 5, "publication_count": 6, "publication_id_list": "10731132;12537569;12537572;12907802;2121539;9109505", "class_list": "", "function": "After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane., [UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 1, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 23, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "O18403;Q8IMW6;Q8SXP7;Q9VC71", "ec_number_list": "", "go_molecular_function": "GO:0004888 transmembrane signaling receptor activity;GO:0022848 acetylcholine-gated monoatomic cation-selective channel activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005892 acetylcholine-gated channel complex;GO:0045202 synapse;GO:0045211 postsynaptic membrane;GO:0043005 neuron projection", "go_biological_process": "GO:0007271 synaptic transmission, cholinergic;GO:0042391 regulation of membrane potential;GO:0007268 chemical synaptic transmission;GO:0034220 monoatomic ion transmembrane transport;GO:0017085 response to insecticide", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P25162-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P25932-1", "uniprot_id": "ESCA_DROME", "mass": 51963.0, "length": 470, "protein_name": "Protein escargot", "gene_name": "esg", "organism": "Fruit fly", "refseq_name": "escargot", "refseq_ac": "NP_476600", "gene_names_uniprotkb": "esg; CG3758; flg", "gene_names_refseq": "4B7; BG01042; BG:DS07851.7; CG3758; Dmel\\CG3758; Esg; br43; dgl; esg; flg; l(2)07082; l(2)35Ce; l(2)4B7; l(2)br43; l(2)esg; l35Ce; shof; wiz", "protein_names_uniprotkb": "Protein escargot; Protein fleabag", "protein_names_refseq": "CG3758-PA; D.m.Escargot; Fusion-1; double glazed; escargot; esg-PA; esgargot; fleabag; shut off; wizard", "tax_id": 7227, "disease": "piebaldism (Disease Ontology:DOID:3263); Waardenburg syndrome (Disease Ontology:DOID:9258)", "pathway": " (dme:Dmel_CG3758)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10471707;10562554;10731132;11902678;12537569;12537572;1571289;7958894;8375329;8620833;9012491", "class_list": "", "function": "Transcription factor that can both stimulate and repress transcription. Binds to the consensus DNA sequence 5'-A/GCAGGTG-3'. Regulates cell motility and adhesion during tracheal morphogenesis by stimulating transcription of the DE-cadherin gene shg at branch tips, thereby promoting tracheal tube fusion. Maintains diploidy in imaginal cells by inhibiting the transcription of genes required for endoreplication. Required for development of the genital disk and acts as an intrinsic determinant of wing cell fate. The somatic protein is required for maintenance of male germ cells. Acts with other members of the snail protein family to control embryonic central nervous system development., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q8SYF2;Q9V3E1", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0001708 cell fate specification;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0035094 response to nicotine;GO:0045944 positive regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "P25932-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P26019-1", "uniprot_id": "DPOLA_DROME", "mass": 169903.0, "length": 1488, "protein_name": "DNA polymerase alpha catalytic subunit", "gene_name": "PolA1", "organism": "Fruit fly", "refseq_name": "DNA polymerase alpha subunit 1", "refseq_ac": "NP_536736", "gene_names_uniprotkb": "PolA1; CG6349; DNApol-alpha180; DNApol-alpha; POLA", "gene_names_refseq": "183 kDa pol alpha; AAB24152; CG6349; Ctf4-polalpha; DNA Pol-alpha180; DNA Polalpha-180; DNA pol alpha; DNA polalpha; DNA polymerase alpha 180 kD; DNA-Polalpha; DNApol-alpha180; DNApol-alpha; DNApolalpha180; DNApolalpha; DNApola; DNApol; DmPolalpha; Dmel\\CG6349; Dmpol alpha; E(mus304); POLA; POlalpha 180kDa; Pol alpha; Pol-alpha180; PolA1; Polalpha 180KDa; Polalpha180; Polalpha; Pol; dpolalphap180; dpolalpha; pol alpha; polalphap180; polalpha", "protein_names_uniprotkb": "DNA polymerase alpha catalytic subunit; 2.7.7.7; 3'-5' exodeoxyribonuclease; 3.1.11.-", "protein_names_refseq": "180 kDa subunit of DNA polymerase alpha; 180 kDa subunit of polymerase-primase; 182-kDa polymerase subunit; CG6349-PA; DNA pol 180; DNA polymerase 180K; DNA polymerase alpha 148,000 alpha subunit; DNA polymerase alpha 180 kD; DNA polymerase alpha 180-kDa subunit; DNA polymerase alpha 180kD subunit; DNA polymerase alpha 180kD; DNA polymerase alpha 182,000 alpha subunit; DNA polymerase alpha subunit 1; DNA polymerase-alpha p180 subunit; DNA polymerase-primase 180 kda subunit; DNA-polymerase alpha; DNApol-alpha180; PolA1-PA; enhancer of mus304", "tax_id": 7227, "disease": "X-linked reticulate pigmentary disorder (Disease Ontology:DOID:0111834); Van Esch-O'Driscoll syndrome (Disease Ontology:DOID:0111840)", "pathway": " (dme:Dmel_CG6349); (R-DME-113501); (R-DME-68952); (R-DME-68962); (R-DME-69091); (R-DME-69166); (R-DME-69183)", "pathway_count": 7, "publication_count": 15, "publication_id_list": "10731132;11493638;12537569;12537572;1429896;18327897;1923767;3112771;3129427;6403945;6409898;6773966;6806812;7592543;9858578", "class_list": "", "function": "Catalytic subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis (PubMed:6403945, PubMed:6409898, PubMed:6773966, PubMed:6806812, PubMed:9858578). During the S phase of the cell cycle, the DNA polymerase alpha complex (composed of a catalytic subunit PolA1, an accessory subunit PolA2 and two primase subunits, the catalytic subunit Prim1 and the regulatory subunit Prim2) is recruited to DNA at the replicative forks (PubMed:6409898, PubMed:6773966, PubMed:6806812, PubMed:9858578). The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands (By similarity). These primers are initially extended by the polymerase alpha catalytic subunit and subsequently transferred to polymerase delta and polymerase epsilon for processive synthesis on the lagging and leading strand, respectively (By similarity). In addition to polymerase activity, exhibits 3' to 5' exonuclease activity (PubMed:3112771, PubMed:3129427)., [UniProtKB, UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "O77034;Q8T992;Q9VD90", "ec_number_list": "2.7.7.7;2.7.11.22;2.7.11.23;3.1.11.-;3.6.4.12;2.7.7.-;3.1.-.-;5.6.2.4", "go_molecular_function": "GO:0003688 DNA replication origin binding;GO:0003887 DNA-directed DNA polymerase activity;GO:0008296 3'-5'-DNA exonuclease activity;GO:0003682 chromatin binding;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005658 alpha DNA polymerase:primase complex;GO:0005634 nucleus", "go_biological_process": "GO:0006272 leading strand elongation;GO:0006273 lagging strand elongation;GO:0045004 DNA replication proofreading;GO:0006270 DNA replication initiation;GO:1902975 mitotic DNA replication initiation", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "P26019-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P27780-1", "uniprot_id": "CUP8_DROME", "mass": 20365.0, "length": 188, "protein_name": "Pupal cuticle protein Edg-84A", "gene_name": "Edg84A", "organism": "Fruit fly", "refseq_name": "Ecdysone-dependent gene 84A", "refseq_ac": "NP_524247", "gene_names_uniprotkb": "Edg84A; CG2345; EDG-84A", "gene_names_refseq": "BG:DS00004.8; CG2345; DM-EDG84; DmelEDG84A; Dmel\\CG2345; EDG-84A; EDG-84; EDG84A; EDG84; Edg84A; Edg84; cc1", "protein_names_uniprotkb": "Pupal cuticle protein Edg-84A", "protein_names_refseq": "CG2345-PA; Ecdysone-dependent gene 84A; Edg84A-PA; cuticle cluster 1; cuticle-like cluster; ecdysone-dependent gene-84A-1", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG2345)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "10731132;12537572;1713868", "class_list": "", "function": "Component of the cuticle of the pupa of fruit fly., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9VI43", "ec_number_list": "", "go_molecular_function": "GO:0008010 structural constituent of chitin-based larval cuticle;GO:0008011 structural constituent of pupal chitin-based cuticle", "go_cellular_component": "GO:0031012 extracellular matrix;GO:0062129 chitin-based extracellular matrix", "go_biological_process": "GO:0040003 chitin-based cuticle development", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "P27780-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P28285-1", "uniprot_id": "5HT2A_DROME", "mass": 89521.0, "length": 834, "protein_name": "5-hydroxytryptamine receptor 2A", "gene_name": "5-HT1A", "organism": "Fruit fly", "refseq_name": "5-hydroxytryptamine (serotonin) receptor 1A, isoform B", "refseq_ac": "NP_725849", "gene_names_uniprotkb": "5-HT1A; 5HT-R2A; CG16720", "gene_names_refseq": "5-HT-1a; 5-HT-dro2A; 5-HT1ADro; 5-HT1A; 5-HT1a; 5-HT[1A]Dro; 5-HT[[1ADro]]; 5-HT[[1A]]DRO; 5-HT[[1A]]; 5-HT; 5HT-1A; 5HT-R2A; 5HT-dro2A; 5HT-drp[[2A]]; 5HT1A; 5HT1a; 5HT[[1ADro]]; 5HT; 5htdro2a; CG16720; DRO2A; Dm5-HT1A; Dm5-HT[[1A]]; Dm5HTdro2A; Dmel\\CG16720; HT1A; d5-HT1A", "protein_names_uniprotkb": "5-hydroxytryptamine receptor 2A; 5-HT receptor 2A; Serotonin receptor 2A", "protein_names_refseq": "5-HT1A-PB; 5-hydroxytryptamine (serotonin) receptor 1A, isoform B; CG16720-PB; serotonin receptor 1A; serotonin receptor 2A; serotonin-receptor-2A", "tax_id": 7227, "disease": "alcohol dependence (Disease Ontology:DOID:0050741); nicotine dependence (Disease Ontology:DOID:0050742); withdrawal disorder (Disease Ontology:DOID:0060001); Alzheimer's disease (Disease Ontology:DOID:10652); antisocial personality disorder (Disease Ontology:DOID:10939); attention deficit hyperactivity disorder (Disease Ontology:DOID:1094); conduct disorder (Disease Ontology:DOID:12995); generalized anxiety disorder (Disease Ontology:DOID:14320); Parkinson's disease (Disease Ontology:DOID:14330); major depressive disorder (Disease Ontology:DOID:1470); alcohol use disorder (Disease Ontology:DOID:1574); depressive disorder (Disease Ontology:DOID:1596); anxiety disorder (Disease Ontology:DOID:2030); substance abuse (Disease Ontology:DOID:302); panic disorder (Disease Ontology:DOID:594); cocaine abuse (Disease Ontology:DOID:809); subacute delirium (Disease Ontology:DOID:8645)", "pathway": " (dme:Dmel_CG16720); (R-DME-390666)", "pathway_count": 2, "publication_count": 4, "publication_id_list": "10731132;12537572;1310937;15611167", "class_list": "", "function": "This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins which inhibit adenylate cyclase., [UniProtKB]", "predicted_glycosites": 9, "predicted_n_glycosites": 8, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 17, "glyco_site_count": 9, "binding_glycan_count": 0, "secondary_ac_list": "Q0E921;Q4QQC9;Q5MTE9;Q5MTF1;Q5MTF2;Q5MTF3;Q5MTF8;Q5MTF9;Q5MTG0;Q5MTG1;Q5MTG2;Q5MTG3;Q5MTG4;Q5MTG6;Q5MTG9;Q5MTH1;Q5MTH2;Q5MTH5;Q5MTH6;Q5MTH7;Q5MTH9;Q5MTI0;Q5MTI1;Q5MTI4;Q5MTI6;Q5MTI7;Q5MTI8;Q5MTJ0;Q5MTJ4;Q5MTJ5;Q5MTJ6;Q5MTJ9;Q5MTK5;Q5MTL1;Q5MTL5;Q5MTL6;Q5MTM2;Q5MTM5;Q5MTM8;Q5MTN6;Q5MTQ1;Q5MTQ4;Q5MTR1;Q5MTR3;Q5MTR6;Q5MTR8;Q5MTS1;Q5MTT8;Q5MTV6;Q5MTV7;Q5MTV9;Q5MTW8;Q5MTX2;Q5MTX7;Q5MTY3;Q5MTY7;Q5MTY8;Q5MTY9;Q5MTZ0;Q5MTZ6;Q5MUJ0;Q5MUK2;Q5MUK5;Q5MUK8;Q5MUL0;Q5MUL2;Q5MUL5;Q5MUM3;Q5MUM7;Q5MUM9;Q5MUN0;Q5MUN1;Q5MUN2;Q5MUP0;Q5MUP5;Q5MUP6;Q5MUP7;Q5MUP8;Q5MUQ1;Q5MUQ6;Q5MUQ7;Q5MUQ8;Q5MUQ9;Q5MUR1;Q5MUR2;Q5MUR3;Q5MUR4;Q5MUR5;Q5MUT3;Q5MUT4;Q5MUT7;Q5MUT9;Q5MUU2;Q5MUU5;Q5MUU6;Q5MUV4;Q5MUV5;Q5MUV8;Q5MUV9;Q5MUW3;Q5MUW4;Q5MUW7;Q5MUX4;Q5MUX6;Q5MUY1;Q5MUY3;Q5MV05;Q5MV06;Q5MV07;Q5MV08;Q5MV13;Q5MV14;Q5MV15;Q5MV26;Q5MV30;Q9V8Q9", "ec_number_list": "", "go_molecular_function": "GO:0004993 G protein-coupled serotonin receptor activity;GO:0030594 neurotransmitter receptor activity;GO:0008227 G protein-coupled amine receptor activity;GO:0001586 Gi/o-coupled serotonin receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane;GO:0030425 dendrite;GO:0045202 synapse", "go_biological_process": "GO:0008049 male courtship behavior;GO:0002121 inter-male aggressive behavior;GO:0045187 regulation of circadian sleep/wake cycle, sleep;GO:0007187 G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007268 chemical synaptic transmission", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P28285-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P29829-1", "uniprot_id": "GBB2_DROME", "mass": 38336.0, "length": 346, "protein_name": "Guanine nucleotide-binding protein subunit beta-2", "gene_name": "Gbeta76C", "organism": "Fruit fly", "refseq_name": "G protein beta subunit 76C", "refseq_ac": "NP_523720", "gene_names_uniprotkb": "Gbeta76C; CG8770; Gb76C; Gbetae; Gbe", "gene_names_refseq": "CG8770; DGqbeta; Dmel\\CG8770; G[[beta76C]]; G[[beta]]e; G[[beta]]; G[q]; Galpha76C; Gbeta76C; Gbeta76c; Gbeta[[e]]; Gbeta_76C; Gbetae; Gbeta{e}; Gbeta; Gbe; Gqbetae; Gqbeta; eGbeta; eye Gbeta; gbe", "protein_names_uniprotkb": "Guanine nucleotide-binding protein subunit beta-2", "protein_names_refseq": "CG8770-PA; G protein beta subunit 76C; G protein beta-subunit 76C; G[[beta]] eye; Gbeta76C-PA; guanine nucleotide regulatory protein beta subunit", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG8770); (R-DME-1296041); (R-DME-418594); (R-DME-418597); (R-DME-428930); (R-DME-6814122); (R-DME-8964616); (R-DME-997272)", "pathway_count": 8, "publication_count": 5, "publication_id_list": "10608815;10731132;12537569;12537572;1910788", "class_list": "", "function": "Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9VW29", "ec_number_list": "", "go_molecular_function": "GO:0046982 protein heterodimerization activity;GO:0016004 phospholipase activator activity;GO:0030159 signaling receptor complex adaptor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0030424 axon;GO:0005834 heterotrimeric G-protein complex;GO:0016028 rhabdomere", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway;GO:0007601 visual perception;GO:0007602 phototransduction;GO:0045879 negative regulation of smoothened signaling pathway;GO:0016059 negative regulation of opsin-mediated signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P29829-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P29844-1", "uniprot_id": "BIP_DROME", "mass": 72261.0, "length": 656, "protein_name": "Endoplasmic reticulum chaperone BiP", "gene_name": "Hsc70-3", "organism": "Fruit fly", "refseq_name": "heat shock protein 70 cognate 3, isoform E", "refseq_ac": "NP_001285139", "gene_names_uniprotkb": "Hsc70-3; CG4147; Hsc3", "gene_names_refseq": "A4V4C4_DROME; BIP; BiP; Bip; CG1579; CG4147; Dmel\\CG4147; GRP78; GRP87/Bip; Grp78; HSC-70; HSC3; HSC70-3; HSC70; HSP70er1; HSP70; HSP7C_DROME; HSPA5; Hsc-3; Hsc-70-3; Hsc3-BiP/GRP78; Hsc3p; Hsc3; Hsc70-3; Hsc70.3; Hsc70; Hsc73; Hsp-c3; anon-WO0138581.7; bip; dBiP; dBip; dhsc70; dmHsc72; grp78; hsc3; hsc70-3; hsc70; hsc72; l(1)G0102; l(1)G0111; l(1)G0292; l(1)G0341; l(1)G0407; l(1)G0466", "protein_names_uniprotkb": "Endoplasmic reticulum chaperone BiP; 3.6.4.10; 78 kDa glucose-regulated protein homolog; BiP; Binding-immunoglobulin protein homolog; GRP-78 homolog; Heat shock 70 kDa protein cognate 3; Heat shock protein cognate 72", "protein_names_refseq": "70 kDa heat shock protein, endoplasmic reticulum 1; CG4147-PE; GRP78; Hsc70-3-PE; glucose-regulated protein 78kD/binding immunoglobulin protein; heat shock 70-kDa protein cognate 3; heat shock cognate protein 3; heat shock protein 70 cognate 3, isoform E; heat shock protein cognate 3; heat shock protein cognate 70-3; heat shock protein cognate 72; heat-shock cognate 70-3; immunoglobulin binding protein", "tax_id": 7227, "disease": "inflammatory bowel disease (Disease Ontology:DOID:0050589); metabolic dysfunction-associated steatohepatitis (Disease Ontology:DOID:0080547); dopamine beta-hydroxylase deficiency (Disease Ontology:DOID:0090145); post-traumatic stress disorder (Disease Ontology:DOID:2055); transient cerebral ischemia (Disease Ontology:DOID:224); high grade glioma (Disease Ontology:DOID:3070); ureteral obstruction (Disease Ontology:DOID:5199); rheumatoid arthritis (Disease Ontology:DOID:7148); steatotic liver disease (Disease Ontology:DOID:9452)", "pathway": " (dme:Dmel_CG4147); (R-DME-3371453)", "pathway_count": 2, "publication_count": 6, "publication_id_list": "10731132;12537572;15952742;25395623;29089387;8514184", "class_list": "", "function": "Endoplasmic reticulum chaperone that plays a key role in protein folding and quality control in the endoplasmic reticulum lumen. Involved in the correct folding of proteins and degradation of misfolded proteins (By similarity). Acts as a key repressor of the unfolded protein response (UPR) (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 9, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A4V4C4;Q86NM3;Q9VYU2;Q9VYU3", "ec_number_list": "2.3.2.-;3.6.4.13;7.2.2.-;3.6.4.-;3.6.4.10;3.6.4.6;3.6.4.12;5.6.2.4;5.6.2.5;2.7.4.3;5.6.2.3;3.1.-.-;3.6.1.15;3.4.21.-;3.-.-.-;5.6.1.1;2.7.11.1;3.6.-.-;5.6.2.-", "go_molecular_function": "GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0031072 heat shock protein binding;GO:0015450 protein-transporting ATPase activity;GO:0044183 protein folding chaperone", "go_cellular_component": "GO:0034663 endoplasmic reticulum chaperone complex;GO:0005615 extracellular space;GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005783 endoplasmic reticulum", "go_biological_process": "GO:0046621 negative regulation of organ growth;GO:0030431 sleep;GO:0035194 regulatory ncRNA-mediated post-transcriptional gene silencing;GO:0030968 endoplasmic reticulum unfolded protein response;GO:0036503 ERAD pathway", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P29844-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P31007-2", "uniprot_id": "DLG1_DROME", "mass": 106673.0, "length": 970, "protein_name": "Disks large 1 tumor suppressor protein", "gene_name": "dlg1", "organism": "Fruit fly", "refseq_name": "discs large 1, isoform K", "refseq_ac": "NP_001096955", "gene_names_uniprotkb": "dlg1; CG1725; l(1)dlg1", "gene_names_refseq": "11; CG1725; CG1730; CPD; DLG-A; DLG1; DLG; Discs Large; Discs-large; Dlg-A; Dlg1; DlgA; DlgS97; Dlg; Dmel\\CG1725; Drodlg; PSD-95; PSD95; SAP97; anon-EST:Posey93; anon-WO03040301.258; anon-WO03040301.260; anon-WO03040301.268; d. lg.-1; dlg-1; dlg-A; dlg1; dlgA; dlgS97; dlg; l(1)10Bf; l(1)G0276; l(1)G0342; l(1)G0456; l(1)G19; l(1)L11; l(1)bwn; l(1)d.lg-1; l(1)d.lg.-1; l(1)discs large; l(1)dlg-1; l(1)dlg1; l(1)dlg; l(1)l.pr.-2; l(1)lpr-2; misb", "protein_names_uniprotkb": "Disks large 1 tumor suppressor protein; Dlg", "protein_names_refseq": "CG1725-PK; Disc-Large; Discs-large 1; Discs-large; disc large; disclarge; discs large 1, isoform K; discs large 1; discslarge; disk large; dlg1-PK; lethal(1)benign wing imaginal disc neoplasm; lethal(1)discs large; lethal(1)discs-large; lethal(2)discs large", "tax_id": 7227, "disease": "non-syndromic X-linked intellectual disability (Disease Ontology:DOID:0050776); developmental disorder of mental health (Disease Ontology:DOID:0060037); autism spectrum disorder (Disease Ontology:DOID:0060041); benign neoplasm (Disease Ontology:DOID:0060072); chromosome 3q29 microdeletion syndrome (Disease Ontology:DOID:0060419); autosomal dominant intellectual developmental disorder 62 (Disease Ontology:DOID:0061035); non-syndromic X-linked intellectual disability 90 (Disease Ontology:DOID:0112041); Alzheimer's disease (Disease Ontology:DOID:10652); Parkinson's disease (Disease Ontology:DOID:14330); cancer (Disease Ontology:DOID:162); Williams-Beuren syndrome (Disease Ontology:DOID:1928); invasive ductal carcinoma (Disease Ontology:DOID:3008); carcinoma (Disease Ontology:DOID:305); temporal lobe epilepsy (Disease Ontology:DOID:3328); kidney disease (Disease Ontology:DOID:557); cervix uteri carcinoma in situ (Disease Ontology:DOID:8991)", "pathway": " (dme:Dmel_CG1725); (R-DME-438066); (R-DME-451308); (R-DME-5625900); (R-DME-6794361); (R-DME-8849932)", "pathway_count": 6, "publication_count": 8, "publication_id_list": "10731132;10884224;12537569;12537572;12657668;1651169;18327897;24768049", "class_list": "", "function": "During embryonic development, some isoforms are essential for proper neuronal differentiation and organization. Required for cell polarity; maintenance of apicobasal polarity. Plays a critical role at septate junctions in cellular growth control during larval development. The presence of a guanylate kinase domain suggests involvement in cellular adhesion as well as signal transduction to control cellular proliferation., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 16, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A4V4A8;A4V4B0;A8JUR9;A8JUS0;C7LAH6;Q7KV38;Q7KV39;Q7KV40;Q7YXH8;Q8SY37;Q8T0C6;Q95TF5;Q9VYZ4;Q9VYZ5;Q9VYZ6", "ec_number_list": "", "go_molecular_function": "GO:0004385 GMP kinase activity;GO:0019901 protein kinase binding", "go_cellular_component": "GO:0045179 apical cortex;GO:0005856 cytoskeleton;GO:0005886 plasma membrane;GO:0005938 cell cortex;GO:0016323 basolateral plasma membrane", "go_biological_process": "GO:0008049 male courtship behavior;GO:0001708 cell fate specification;GO:0051294 establishment of spindle orientation;GO:0007165 signal transduction;GO:0007399 nervous system development", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P31007-2", "record_type": "protein" }, { "uniprot_canonical_ac": "P32027-1", "uniprot_id": "CROC_DROME", "mass": 54517.0, "length": 508, "protein_name": "Fork head domain-containing protein crocodile", "gene_name": "croc", "organism": "Fruit fly", "refseq_name": "crocodile", "refseq_ac": "NP_524202", "gene_names_uniprotkb": "croc; CG5069; FD1; FD78E", "gene_names_refseq": "CG5069; Croc; Dm-FoxC; Dmel\\CG5069; Dmfd1; FD1; FoxC; croc; fd1; fd78E", "protein_names_uniprotkb": "Fork head domain-containing protein crocodile; FKH protein FD1", "protein_names_refseq": "CG5069-PA; FD1 transcription unit; croc-PA; crocodile; forkhead domain 78E", "tax_id": 7227, "disease": "ptosis (Disease Ontology:DOID:0060260); anterior segment dysgenesis 3 (Disease Ontology:DOID:0080608); Axenfeld-Rieger syndrome type 3 (Disease Ontology:DOID:0110122); lymphedema-distichiasis syndrome (Disease Ontology:DOID:0111509); nephritis (Disease Ontology:DOID:10952); buphthalmos (Disease Ontology:DOID:11211); Axenfeld-Rieger syndrome (Disease Ontology:DOID:14686); glaucoma (Disease Ontology:DOID:1686); invasive ductal carcinoma (Disease Ontology:DOID:3008); lymphedema (Disease Ontology:DOID:4977); eyelid disease (Disease Ontology:DOID:530); congestive heart failure (Disease Ontology:DOID:6000); type 2 diabetes mellitus (Disease Ontology:DOID:9352); obesity (Disease Ontology:DOID:9970)", "pathway": " (dme:Dmel_CG5069)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "10731132;12537572;1356269;7489720", "class_list": "", "function": "Required for the establishment of head structures. Required to function as an early patterning gene in the anterior-most blastoderm head segment anlage and for the establishment of a specific head skeletal structure that derives from the non-adjacent intercalary segment at a later stage of embryogenesis. Binds the consensus DNA sequence 5'-[AG]TAAA[TC]A-3'., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 14, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9VP32", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0030154 cell differentiation;GO:0009653 anatomical structure morphogenesis;GO:0007380 specification of segmental identity, head", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P32027-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P32029-1", "uniprot_id": "FD5_DROME", "mass": 31013.0, "length": 271, "protein_name": "Fork head domain-containing protein FD5", "gene_name": "fd96Cb", "organism": "Fruit fly", "refseq_name": "forkhead domain 96Cb", "refseq_ac": "NP_524496", "gene_names_uniprotkb": "fd96Cb; CG11922; FD5", "gene_names_refseq": "CG11922; Dm-FoxB2; Dmel\\CG11922; Dmfd5; FD5; FoxB; fd5; fd96Cb", "protein_names_uniprotkb": "Fork head domain-containing protein FD5", "protein_names_refseq": "CG11922-PA; fd96Cb-PA; forkhead domain 96Cb", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG11922)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "10731132;12537572;1356269", "class_list": "", "function": "Involved in development during embryogenesis., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q0IGQ4;Q9VBY0", "ec_number_list": "", "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0030154 cell differentiation;GO:0009653 anatomical structure morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "P32029-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P32234-1", "uniprot_id": "128UP_DROME", "mass": 41132.0, "length": 368, "protein_name": "Guanylate binding protein 128up", "gene_name": "128up", "organism": "Fruit fly", "refseq_name": "upstream of RpIII128", "refseq_ac": "NP_536733", "gene_names_uniprotkb": "128up; CG8340; GBP; GTP-bp", "gene_names_refseq": "128up; CG8340; Dmel\\CG8340; GBP; GTP-bp; Gtp-bp; X71866", "protein_names_uniprotkb": "Guanylate binding protein 128up; GTP-binding protein; Protein upstream of RpIII128", "protein_names_refseq": "128up-PA; CG8340-PA; upstream of RpIII128", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG8340); (R-DME-9629569)", "pathway_count": 2, "publication_count": 5, "publication_id_list": "10731132;12537572;35410347;8104141;8121394", "class_list": "", "function": "Catalyzes the conversion of GTP to GDP through hydrolysis of the gamma-phosphate bond in GTP (By similarity). Dfd/deformed is required to activate 128up in maxillary segment cells., [UniProtKB, PubMed, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9V648", "ec_number_list": "", "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0002181 cytoplasmic translation", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P32234-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P33450-1", "uniprot_id": "FAT_DROME", "mass": 564791.0, "length": 5147, "protein_name": "Cadherin-related tumor suppressor", "gene_name": "ft", "organism": "Fruit fly", "refseq_name": "fat", "refseq_ac": "NP_477497", "gene_names_uniprotkb": "ft; CG3352", "gene_names_refseq": "79/18; CG3352; CT11259; Dm Fat; Dmel\\CG3352; FT; Fat; Ft; ft; l(2)24Da; l(2)79/18; l(2)fat; l(2)fd; l(2)ft; l(2)gd-1; l(2)gd-l; l(2)gd2; l(2)k07918", "protein_names_uniprotkb": "Cadherin-related tumor suppressor; Protein fat", "protein_names_refseq": "CG3352-PA; fat; floppy-discs; ft-PA; giant discs 2; giant-discs-1", "tax_id": 7227, "disease": "Hennekam syndrome (Disease Ontology:DOID:0060366); Van Maldergem syndrome 2 (Disease Ontology:DOID:0080586); neurodegenerative disease (Disease Ontology:DOID:1289); carcinoma (Disease Ontology:DOID:305); obesity (Disease Ontology:DOID:9970)", "pathway": " (dme:Dmel_CG3352); (R-DME-350379); (R-DME-390023); (R-DME-390150)", "pathway_count": 4, "publication_count": 32, "publication_id_list": "10490098;10731132;11893338;12015972;12506006;12537572;12540853;12642492;12756182;12941274;12941693;14502295;15240556;15548581;16687445;16735478;16980976;16996265;17174922;18327897;18555784;18635802;18804371;18849982;19540118;19574458;1959133;19710173;20434335;23667559;25107277;25215488", "class_list": "", "function": "Involved in regulation of planar cell polarity in the compound eye where it is required for correct specification of the R3 and R4 photoreceptor cells by regulating Fz activity in the R3/R4 precursor cells (PubMed:11893338). This is likely to occur through creation of an ft gradient so that the equatorial R3/R4 precursor cell has a higher level of ft function than its polar neighbor (PubMed:15548581). Also required for planar cell polarity of wing hairs (PubMed:12540853, PubMed:15240556). Mediates heterophilic cell adhesion in vitro and is required to stabilize ds on the cell surface (PubMed:15240556). Involved in regulation of eye imaginal disk size (PubMed:23667559). Upstream component of the Hippo pathway where it is likely to act as a cell surface receptor involved in regulation of tissue size and is required for the localization and stability of ex (PubMed:16996265). Probably acts as a cell surface receptor for ds (PubMed:20434335)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]; Regulates mitochondrial electron transport chain integrity and promotes oxidative phosphorylation., [UniProtKB, PubMed]", "predicted_glycosites": 40, "predicted_n_glycosites": 38, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 3, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 40, "binding_glycan_count": 0, "secondary_ac_list": "Q9VQX5", "ec_number_list": "", "go_molecular_function": "GO:0005509 calcium ion binding;GO:0045296 cadherin binding", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005886 plasma membrane;GO:0005912 adherens junction;GO:0016324 apical plasma membrane;GO:0016327 apicolateral plasma membrane", "go_biological_process": "GO:0046621 negative regulation of organ growth;GO:0007409 axonogenesis;GO:0008285 negative regulation of cell population proliferation;GO:0010629 negative regulation of gene expression;GO:0030855 epithelial cell differentiation", "synthesized_glycan_count": 0, "hit_score": 3.3, "record_id": "P33450-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P35381-1", "uniprot_id": "ATPA_DROME", "mass": 59422.0, "length": 552, "protein_name": "ATP synthase subunit alpha, mitochondrial", "gene_name": "blw", "organism": "Fruit fly", "refseq_name": "bellwether", "refseq_ac": "NP_726243", "gene_names_uniprotkb": "blw; ATPSYN-ALPHA; CG3612", "gene_names_refseq": "A2(2nd)27; ATP syn-alpha; ATP5A; ATP5F1A; ATP5alpha; ATP5a; ATPA_DROME; ATPA; ATPsyn-alpha; ATPsyn-a; ATPsynalpha; Atp5a; Blw; C-V-alpha; C-Va; CG3612; CValpha; CxV; Dmel\\CG3612; blw; dATP5A; l(2)01410; l(2)03972; l(2)59ABa; l(2)k00212; ms(2)01504; ms(2)Pry58F", "protein_names_uniprotkb": "ATP synthase subunit alpha, mitochondrial; Protein bellwether", "protein_names_refseq": "ATP SYNTHASE ALPHA; ATP VDRC synthase F1F0; ATP synthase alpha chain; ATP synthase alpha subunit of complex V; ATP synthase subunit alpha; ATP synthase subunits alpha; ATP synthase, alpha subunit; ATP synthase, subunit alpha; ATP synthetase alpha chain; CG3612-PA; COMPLEX V: alpha chain; F0/F1 ATP synthase alpha; alpha subunit of ATP synthase; alpha subunit of the mitochondrial F[[1]]F[[0]] ATPase; alpha-ATP synthase; alpha-subunit of ATP synthase; bellweather; bellwether; blw-PA; colibri; complex V alpha; complex Va; complex valpha subunit; mitochondrial ATP synthase alpha subunit; mitochondrial ATP synthase subunit B; mitochondrial ATP synthase subunit alpha of complex V; mitochondrial ATPase complex V-subunit alpha", "tax_id": 7227, "disease": "mitochondrial complex V (ATP synthase) deficiency nuclear type 4A (Disease Ontology:DOID:0070461); mitochondrial complex V (ATP synthase) deficiency nuclear type 4B (Disease Ontology:DOID:0070462); metabolic dysfunction-associated steatotic liver disease (Disease Ontology:DOID:0080208); combined oxidative phosphorylation deficiency 22 (Disease Ontology:DOID:0111498); Alzheimer's disease (Disease Ontology:DOID:10652); hypertension (Disease Ontology:DOID:10763); pulmonary hypertension (Disease Ontology:DOID:6432); vascular dementia (Disease Ontology:DOID:8725)", "pathway": " (dme:Dmel_CG3612); (R-DME-163210); (R-DME-8949613); (R-DME-9837999)", "pathway_count": 4, "publication_count": 4, "publication_id_list": "10731132;12537572;8500545;9540069", "class_list": "", "function": "Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Subunits alpha and beta form the catalytic core in F(1). Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits. Subunit alpha does not bear the catalytic high-affinity ATP-binding sites (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 8, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q53YF5;Q94512;Q9W1Z7", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0043531 ADP binding;GO:0046933 proton-transporting ATP synthase activity, rotational mechanism", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane;GO:0045259 proton-transporting ATP synthase complex", "go_biological_process": "GO:0019915 lipid storage;GO:0015986 proton motive force-driven ATP synthesis;GO:0022900 electron transport chain", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P35381-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P36192-1", "uniprot_id": "DEFI_DROME", "mass": 10190.0, "length": 92, "protein_name": "Defensin", "gene_name": "Def", "organism": "Fruit fly", "refseq_name": "defensin", "refseq_ac": "NP_523672", "gene_names_uniprotkb": "Def; CG1385", "gene_names_refseq": "143607_at; CG1385; DEF; DIM 26; Def; Dfn; Dmel\\CG1385; defensin; def", "protein_names_uniprotkb": "Defensin", "protein_names_refseq": "CG1385-PA; Def-PA; defencin; defensin precursor; defensin; definsin", "tax_id": 7227, "disease": "neurodegenerative disease (Disease Ontology:DOID:1289)", "pathway": " (dme:Dmel_CG1385)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "10731132;12537572;12716986;16510152;8168509", "class_list": "", "function": "Responsible for the anti Gram-positive activity of immune hemolymph. Expressed in the absence of immune challenge during metamorphosis., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q4V3H2;Q867E6;Q867G6;Q86BV6;Q86BV7;Q9V5F5", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0019731 antibacterial humoral response;GO:0045087 innate immune response;GO:0050830 defense response to Gram-positive bacterium;GO:0009617 response to bacterium;GO:0042742 defense response to bacterium", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P36192-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P36951-1", "uniprot_id": "HYI_DROME", "mass": 29093.0, "length": 264, "protein_name": "Putative hydroxypyruvate isomerase", "gene_name": "Gip", "organism": "Fruit fly", "refseq_name": "GIP-like", "refseq_ac": "NP_511106", "gene_names_uniprotkb": "Gip; CG2227", "gene_names_refseq": "CG2227; Dmel\\CG2227; GIP; Gip; T15; gene C", "protein_names_uniprotkb": "Putative hydroxypyruvate isomerase; 5.3.1.22; GIP-like protein; Transient receptor potential locus C protein", "protein_names_refseq": "CG2227-PA; GIP-like; Gip-PA; glyoxylate-induced protein; hydroxypyruvate isomerase", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG2227)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "10731132;12537569;12537572;3118483", "class_list": "", "function": "Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9W2W4", "ec_number_list": "5.3.1.22", "go_molecular_function": "GO:0008903 hydroxypyruvate isomerase activity", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "GO:0046487 glyoxylate metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P36951-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P38040-1", "uniprot_id": "GBG1_DROME", "mass": 8130.0, "length": 70, "protein_name": "Guanine nucleotide-binding protein subunit gamma-1", "gene_name": "Ggamma1", "organism": "Fruit fly", "refseq_name": "G protein gamma subunit 1, isoform C", "refseq_ac": "NP_523662", "gene_names_uniprotkb": "Ggamma1; CG8261; G1", "gene_names_refseq": "CG8261; D-G[[gamma]]1; Dmel\\CG8261; G protein gamma; GNG13; G[[gamma1]]; G[[gamma]]; Gbetagamma; Gg1; Ggamma-1; Ggamma1; Ggamma; bro4; dg1alpha; ggamma1; l(2)k08017", "protein_names_uniprotkb": "Guanine nucleotide-binding protein subunit gamma-1", "protein_names_refseq": "CG8261-PC; G protein Gg1; G protein gamma 1; G protein gamma subunit 1, isoform C; G protein gamma1; G protein subunit gamma1; G-protein gamma subunit 1; Ggamma1-PC", "tax_id": 7227, "disease": "obesity (Disease Ontology:DOID:9970)", "pathway": " (dme:Dmel_CG8261)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "10731132;12537569;12537572;1372898", "class_list": "", "function": "Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A4UZ90;Q540Y8;Q9V4Z3", "ec_number_list": "", "go_molecular_function": "GO:0031681 G-protein beta-subunit binding", "go_cellular_component": "GO:0005834 heterotrimeric G-protein complex", "go_biological_process": "GO:0010470 regulation of gastrulation;GO:0007186 G protein-coupled receptor signaling pathway;GO:0035050 embryonic heart tube development;GO:0055059 asymmetric neuroblast division;GO:0043519 regulation of myosin II filament organization", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P38040-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P40794-1", "uniprot_id": "BNK_DROME", "mass": 33566.0, "length": 303, "protein_name": "Protein bottleneck", "gene_name": "bnk", "organism": "Fruit fly", "refseq_name": "bottleneck", "refseq_ac": "NP_524604", "gene_names_uniprotkb": "bnk; CG1480", "gene_names_refseq": "Bnk; CG1480; Dmel\\CG1480; bnk", "protein_names_uniprotkb": "Protein bottleneck", "protein_names_refseq": "CG1480-PA; bnk-PA; bottleneck", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG1480)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "10731132;12537572;8402919", "class_list": "", "function": "Acts as a regulator of the microfilament network governing cellularization of the embryo. Determines the timing of a key conformational transition in the cortical microfilament network: the proper coordination of membrane invagination and basal closure of the cells. To do this, bnk possibly physically links neighboring contractile units of the early cycle 14 microfilament network in a manner that prevents basal constriction until the proper stage has been reached. Bnk together with nullo and Sry-alpha may provide auxiliary functions, by acting both to stabilize a large and dynamic microfilament structure and regulate its functions., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9VA03", "ec_number_list": "", "go_molecular_function": "GO:0005546 phosphatidylinositol-4,5-bisphosphate binding;GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding;GO:0051015 actin filament binding", "go_cellular_component": "GO:0005884 actin filament", "go_biological_process": "GO:0061572 actin filament bundle organization;GO:0007015 actin filament organization;GO:0051017 actin filament bundle assembly;GO:0016476 regulation of embryonic cell shape;GO:0110069 syncytial embryo cellularization", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "P40794-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P40807-1", "uniprot_id": "DCOR1_DROME", "mass": 44195.0, "length": 394, "protein_name": "Ornithine decarboxylase 1", "gene_name": "Odc1", "organism": "Fruit fly", "refseq_name": "ornithine decarboxylase 1", "refseq_ac": "NP_477052", "gene_names_uniprotkb": "Odc1; CG8721", "gene_names_refseq": "CG8721; Dmel\\CG8721; Odc-1; Odc1; dodc1", "protein_names_uniprotkb": "Ornithine decarboxylase 1; 4.1.1.17; ODC", "protein_names_refseq": "CG8721-PA; Odc1-PA; ornithine decarboxylase 1; ornithine decarboxylase-1", "tax_id": 7227, "disease": "atrichia with papular lesions (Disease Ontology:DOID:0060689); pneumocystosis (Disease Ontology:DOID:11339); esophagus squamous cell carcinoma (Disease Ontology:DOID:3748); liver cirrhosis (Disease Ontology:DOID:5082); hepatocellular carcinoma (Disease Ontology:DOID:684)", "pathway": " (dme:Dmel_CG8721); (R-DME-350562); (R-DME-351143)", "pathway_count": 3, "publication_count": 4, "publication_id_list": "10731132;12537569;12537572;8329117", "class_list": "", "function": "Catalyzes the first and rate-limiting step of polyamine biosynthesis that converts ornithine into putrescine, which is the precursor for the polyamines, spermidine and spermine. Polyamines are essential for cell proliferation and are implicated in cellular processes, ranging from DNA replication to apoptosis., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9V352", "ec_number_list": "4.1.1.17", "go_molecular_function": "GO:0004586 ornithine decarboxylase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0033387 putrescine biosynthetic process from arginine, via ornithine", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P40807-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P41572-1", "uniprot_id": "6PGD_DROME", "mass": 52491.0, "length": 481, "protein_name": "6-phosphogluconate dehydrogenase, decarboxylating", "gene_name": "Pgd", "organism": "Fruit fly", "refseq_name": "phosphogluconate dehydrogenase, isoform B", "refseq_ac": "NP_001259175", "gene_names_uniprotkb": "Pgd; CG3724", "gene_names_refseq": "6-PGD; 6-Pgd; 6-pgd; 6PGDH; 6PGD; 6Pgdh; 6Pgd; 6pgdh; A7; CG3724; DmG6PDH; Dmel\\CG3724; EG:87B1.4; N1; PGD; Pdg; Pgd; l(1)2Dc; l(1)2De; l(1)A7; l(1)G0385; l(1)N1; l(1)N3[90]; l(1)Pgd-A; l(1)Pgd; l35; pgd", "protein_names_uniprotkb": "6-phosphogluconate dehydrogenase, decarboxylating; 1.1.1.44", "protein_names_refseq": "6-phosphogluconate dehydrogenase; CG3724-PB; NADP-6 phosphogluconate dehydrogenase; Pgd-PB; phosphogluconate dehydrogenase, isoform B; phosphogluconate dehydrogenase", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG3724); (R-DME-71336)", "pathway_count": 2, "publication_count": 6, "publication_id_list": "10731132;10731137;12537569;12537572;1765265;25855066", "class_list": "", "function": "Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "M9PIS3;Q9W519", "ec_number_list": "1.1.1.44", "go_molecular_function": "GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity;GO:0050661 NADP binding", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0009051 pentose-phosphate shunt, oxidative branch;GO:0042593 glucose homeostasis;GO:0019521 D-gluconate metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P41572-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P42281-1", "uniprot_id": "ACBP_DROME", "mass": 9557.0, "length": 86, "protein_name": "Acyl-CoA-binding protein homolog", "gene_name": "Acbp2", "organism": "Fruit fly", "refseq_name": "Acyl-CoA binding protein 2, isoform B", "refseq_ac": "NP_523952", "gene_names_uniprotkb": "Acbp2; CG8627; Dbi", "gene_names_refseq": "ACBP; Acbp2; BcDNA:RH39533; CG8627; DBI; Dbi; DmDBI; Dmel\\CG8627; anon-WO0172774.131; dbi", "protein_names_uniprotkb": "Acyl-CoA-binding protein homolog; ACBP; DBI; Diazepam-binding inhibitor homolog", "protein_names_refseq": "Acbp2-PB; Acyl-CoA binding protein 2, isoform B; CG8627-PB; Diazepam-binding inhibitor; acyl-CoA binding protein; acyl-CoA-binding protein; diazepam binding inhibitor; diazepam-binding protein; endozepine", "tax_id": 7227, "disease": "alcohol dependence (Disease Ontology:DOID:0050741); cardiovascular system disease (Disease Ontology:DOID:1287); morphine dependence (Disease Ontology:DOID:2560)", "pathway": " (dme:Dmel_CG8627); (R-DME-77289)", "pathway_count": 2, "publication_count": 4, "publication_id_list": "10731132;12537569;12537572;7935415", "class_list": "", "function": "Binds medium- and long-chain acyl-CoA esters with very high affinity and may function as an intracellular carrier of acyl-CoA esters (By similarity). May be involved in energy metabolism in a manner that depends on the substrate used for energy production. Dbi and its metabolites are involved in the regulation of multiple biological processes., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A4V1K8;Q9VS23", "ec_number_list": "", "go_molecular_function": "GO:0000062 fatty-acyl-CoA binding", "go_cellular_component": "", "go_biological_process": "GO:0006631 fatty acid metabolic process;GO:0019915 lipid storage;GO:0042049 intracellular acyl-CoA homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P42281-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q867Z4-1", "uniprot_id": "LOLA4_DROME", "mass": 105812.0, "length": 970, "protein_name": "Longitudinals lacking protein, isoforms F/I/K/T", "gene_name": "lola", "organism": "Fruit fly", "refseq_name": "longitudinals lacking, isoform F", "refseq_ac": "NP_724952", "gene_names_uniprotkb": "lola; CG12052", "gene_names_refseq": "BEST:LD03274; BTB-IV; BcDNA:LD17006; BcDNA:RH31485; BtbIV; CG12052; CG18376; CG18378; CG18379; CG18380; CG18381; CG30012; CG30013; CG30014; Dmel\\CG12052; LD03274; LOLA; Lola; NEST:bs06a08; bs06a08.y1; btb; eyeful; fus7; l(2)00642; l(2)s3697; lola; sw59", "protein_names_uniprotkb": "Longitudinals lacking protein, isoforms F/I/K/T", "protein_names_refseq": "BTB-protein-IV; CG12052-PF; SGP cluster fusion defects 7; bumper-to-bumper; eyeful; e; lola-PF; longitudinal lacking; longitudinals absent; longitudinals lacking, isoform F; longitudinals lacking; longitudinals-lacking; misguided", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG12052)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "10731132;11880341;12537569;12537572;12538650;12853139;12897787;14522953;18327897;33925313;40245499;8050351", "class_list": "", "function": "Putative transcription factor required for axon growth and guidance in the central and peripheral nervous systems. Repels CNS axons away from the midline by promoting the expression of the midline repellent sli and its receptor robo., [UniProtKB, PubMed, PubMed, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 11, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "A4UZC3;Q867F7;Q867K2;Q867T0;Q86BC3;Q8MKX6;Q8MZH5", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0003700 DNA-binding transcription factor activity;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0007409 axonogenesis;GO:0016199 axon midline choice point recognition;GO:0006355 regulation of DNA-templated transcription;GO:0045893 positive regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "Q867Z4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P42287-1", "uniprot_id": "GRK_DROME", "mass": 33280.0, "length": 295, "protein_name": "Protein gurken", "gene_name": "grk", "organism": "Fruit fly", "refseq_name": "gurken", "refseq_ac": "NP_476568", "gene_names_uniprotkb": "grk; CG17610", "gene_names_refseq": "CG17610; CT32746; Dmel\\CG17610; GRK; Grk; Gurken; grk; s-Grk", "protein_names_uniprotkb": "Protein gurken", "protein_names_refseq": "CG17610-PA; Gurken/epidermal growth factor; grk-PA; gurken", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG17610)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "10731132;10790337;12537569;12537572;16396907;7691414", "class_list": "", "function": "Critical for defining the anterior-posterior and dorsal-ventral axes of the egg. May signal directly to dorsal follicle cells through the receptor torpedo (top). During oogenesis this signaling pathway instructs follicle cells to follow a dorsal pathway of development rather than the default ventral pathway., [UniProtKB, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "Q9VLL2", "ec_number_list": "", "go_molecular_function": "GO:0005154 epidermal growth factor receptor binding;GO:0048018 receptor ligand activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005886 plasma membrane", "go_biological_process": "GO:0007166 cell surface receptor signaling pathway;GO:0007173 epidermal growth factor receptor signaling pathway;GO:0009952 anterior/posterior pattern specification;GO:0048263 determination of dorsal identity;GO:0008070 maternal determination of dorsal/ventral axis, ovarian follicular epithelium, germ-line encoded", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P42287-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P45437-1", "uniprot_id": "COPB_DROME", "mass": 107407.0, "length": 964, "protein_name": "Coatomer subunit beta", "gene_name": "betaCOP", "organism": "Fruit fly", "refseq_name": "coat protein (coatomer) beta", "refseq_ac": "NP_523400", "gene_names_uniprotkb": "betaCOP; CG6223", "gene_names_refseq": "BcDNA.GH09317; BcDNA:GH09317; Bcop; Beta Cop; BetaCop; CG6223; COPI; Dmel\\CG6223; bcop; beta COP; beta-COP; beta-CopII; beta-Cop; betaCOP; betaCop", "protein_names_uniprotkb": "Coatomer subunit beta; Beta-COP; Beta-coat protein", "protein_names_refseq": "CG6223-PA; COPI beta subunit; beta coatomer protein; beta-coatomer protein; betaCOP-PA; betaCop; coat protein (coatomer) beta", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG6223); (R-DME-6798695); (R-DME-6807878); (R-DME-6811434)", "pathway_count": 4, "publication_count": 10, "publication_id_list": "10731132;10953008;11533661;12537569;12537572;16169286;16452979;19067489;40245499;8127899", "class_list": "", "function": "The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. Required for limiting lipid storage in lipid droplets., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q9VWV7;Q9Y116", "ec_number_list": "", "go_molecular_function": "GO:0005198 structural molecule activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005794 Golgi apparatus;GO:0030126 COPI vesicle coat", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0050829 defense response to Gram-negative bacterium;GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0006890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum;GO:0010883 regulation of lipid storage", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "P45437-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P45884-1", "uniprot_id": "ATTA_DROME", "mass": 23239.0, "length": 224, "protein_name": "Attacin-A", "gene_name": "AttA", "organism": "Fruit fly", "refseq_name": "Attacin-A", "refseq_ac": "NP_523745", "gene_names_uniprotkb": "AttA; CG10146", "gene_names_refseq": "AHA; ATT; Att A; Att-A; AttA; AttaA; Attacin A; AttacinA; Att; BcDNA:LP05763; CG10146; Dmel\\CG10146; anon-WO0140519.5; att A; attA; attacin; att", "protein_names_uniprotkb": "Attacin-A", "protein_names_refseq": "AttA-PA; Attacin-A precursor; Attacin-A; CG10146-PA; attacin A; attacinA; attackin", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG10146)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "10731132;10767526;12537572;16510152;7742836", "class_list": "", "function": "Hemolymph antibacterial protein., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9V750", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0019731 antibacterial humoral response;GO:0045087 innate immune response;GO:0050829 defense response to Gram-negative bacterium;GO:0050830 defense response to Gram-positive bacterium;GO:0006959 humoral immune response", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P45884-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P45888-1", "uniprot_id": "ARP2_DROME", "mass": 45282.0, "length": 399, "protein_name": "Actin-related protein 2", "gene_name": "Arp2", "organism": "Fruit fly", "refseq_name": "Actin-related protein 2, isoform B", "refseq_ac": "NP_001097001", "gene_names_uniprotkb": "Arp2; Actr14D; Arp14D; CG9901", "gene_names_refseq": "ARP14D; ARP2; Actr14D; Arp14D; Arp14d; Arp2; CG9901; Dmel\\CG9901; arp2", "protein_names_uniprotkb": "Actin-related protein 2; Actin-like protein 14D; Actin-like protein 2", "protein_names_refseq": "Actin-related protein 14 Da; Actin-related protein 14D; Actin-related protein 2, isoform B; Arp14D; Arp2-PB; CG9901-PB", "tax_id": 7227, "disease": "colorectal carcinoma (Disease Ontology:DOID:0080199); lung disease (Disease Ontology:DOID:850)", "pathway": " (dme:Dmel_CG9901); (R-DME-2029482); (R-DME-3928662); (R-DME-5663213); (R-DME-6798695); (R-DME-8856828)", "pathway_count": 6, "publication_count": 4, "publication_id_list": "10731132;12537569;12537572;8064864", "class_list": "", "function": "Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A8JV17;F0JAK9;Q9VXF3", "ec_number_list": "", "go_molecular_function": "GO:0003779 actin binding;GO:0005200 structural constituent of cytoskeleton;GO:0005524 ATP binding", "go_cellular_component": "GO:0005884 actin filament;GO:0005938 cell cortex;GO:0015629 actin cytoskeleton;GO:0005885 Arp2/3 protein complex", "go_biological_process": "GO:0072553 terminal button organization;GO:0007015 actin filament organization;GO:0030032 lamellipodium assembly;GO:0035313 wound healing, spreading of epidermal cells;GO:0034314 Arp2/3 complex-mediated actin nucleation", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P45888-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P45889-1", "uniprot_id": "ACTZ_DROME", "mass": 42719.0, "length": 376, "protein_name": "Actin-related protein 1", "gene_name": "Arp1", "organism": "Fruit fly", "refseq_name": "Actin-related protein 1", "refseq_ac": "NP_524331", "gene_names_uniprotkb": "Arp1; Actr87C; Arp87C; CG6174", "gene_names_refseq": "ARP1; ARP87C; Actr87C; Arp-1; Arp1; Arp87C; Arp87c; Arp; CG6174; Dmel\\CG6174; arp-1; arp1; gdl; grid", "protein_names_uniprotkb": "Actin-related protein 1; Actin-like protein 1; Actin-like protein 87C", "protein_names_refseq": "Actin-related protein 1; Actin-related protein 87C; Arp1-PA; CG6174-PA; actin related protein 1; gridlock", "tax_id": 7227, "disease": "Down syndrome (Disease Ontology:DOID:14250); colon cancer (Disease Ontology:DOID:219)", "pathway": " (dme:Dmel_CG6174); (R-DME-3371497); (R-DME-6798695); (R-DME-6807878); (R-DME-6811436)", "pathway_count": 5, "publication_count": 5, "publication_id_list": "10731132;12537569;12537572;40245499;8064864", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 2, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q9VG37", "ec_number_list": "", "go_molecular_function": "GO:0005200 structural constituent of cytoskeleton;GO:0005524 ATP binding", "go_cellular_component": "GO:0005869 dynactin complex;GO:1904115 axon cytoplasm", "go_biological_process": "GO:0008090 retrograde axonal transport;GO:0000278 mitotic cell cycle;GO:0007018 microtubule-based movement;GO:0008089 anterograde axonal transport;GO:0019896 axonal transport of mitochondrion", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P45889-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P45891-1", "uniprot_id": "ACTY_DROME", "mass": 42030.0, "length": 376, "protein_name": "Actin-like protein 53D", "gene_name": "Arp53D", "organism": "Fruit fly", "refseq_name": "Actin-related protein 53D", "refseq_ac": "NP_477037", "gene_names_uniprotkb": "Arp53D; Actr53D; CG5409", "gene_names_refseq": "ARP53D; Actr53D; Arp53D; ArpG; Arp_G; CG5409; Dmel\\CG5409; arp53D; arp5", "protein_names_uniprotkb": "Actin-like protein 53D", "protein_names_refseq": "Actin-related protein 53D; Arp53D-PB; CG5409-PB", "tax_id": 7227, "disease": "spermatogenic failure 86 (Disease Ontology:DOID:0070585); aortic dissection (Disease Ontology:DOID:0080685); Baraitser-Winter syndrome 1 (Disease Ontology:DOID:0081112); congenital myopathy 2B (Disease Ontology:DOID:0081339); congenital myopathy 2C (Disease Ontology:DOID:0081340); autosomal dominant nonsyndromic deafness 20 (Disease Ontology:DOID:0110550); nemaline myopathy 3 (Disease Ontology:DOID:0110927); spermatogenic failure 53 (Disease Ontology:DOID:0112279); intestinal atresia (Disease Ontology:DOID:10486); male infertility (Disease Ontology:DOID:12336); Moyamoya disease (Disease Ontology:DOID:13099); patent ductus arteriosus (Disease Ontology:DOID:13832); thoracic aortic aneurysm (Disease Ontology:DOID:14004); bladder urothelial carcinoma (Disease Ontology:DOID:4006)", "pathway": " (dme:Dmel_CG5409); (R-DME-445355); (R-DME-8980692); (R-DME-9764561); (R-DME-9913351); (R-DME-9958825)", "pathway_count": 6, "publication_count": 4, "publication_id_list": "10731132;12537572;34282725;8064864", "class_list": "", "function": "Required for optimal embryo development, particularly under heat stress conditions (PubMed:34282725). Also appears to have a role in negatively regulating spermatocyte cyst development (PubMed:34282725). Under heat stress conditions, required for the correct organization and migration of nuclei during early embryogenesis, and therefore possibly functions by regulating embryonic actin networks during the heat stress response (PubMed:34282725)., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 14, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9V7T9", "ec_number_list": "", "go_molecular_function": "GO:0005200 structural constituent of cytoskeleton;GO:0005524 ATP binding", "go_cellular_component": "GO:0015629 actin cytoskeleton;GO:0045169 fusome", "go_biological_process": "GO:0007286 spermatid development;GO:0040019 positive regulation of embryonic development", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P45891-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P46415-1", "uniprot_id": "ADHX_DROME", "mass": 40389.0, "length": 379, "protein_name": "Alcohol dehydrogenase class-3", "gene_name": "Fdh", "organism": "Fruit fly", "refseq_name": "formaldehyde dehydrogenase", "refseq_ac": "NP_524310", "gene_names_uniprotkb": "Fdh; CG6598; ODH; gfd", "gene_names_refseq": "ADHX_DROME; ADHX; CG6598; Dmel\\CG6598; Fdh; GSNOR; ODH; Odh; fdh; gfd/odh; gfd; odh", "protein_names_uniprotkb": "Alcohol dehydrogenase class-3; 1.1.1.-; 1.1.1.1; 1.1.1.284; 1.1.1.73; Alcohol dehydrogenase class-III; FALDH; FDH; GSH-FDH; Glutathione-dependent formaldehyde dehydrogenase; Octanol dehydrogenase; S-(hydroxymethyl)glutathione dehydrogenase", "protein_names_refseq": "ADH; CG6598-PA; Fdh-PA; formaldehyde dehydrogenase; glutathione-dependent formaldehyde dehydrogenase; octanol dehydrogenase", "tax_id": 7227, "disease": "alcohol dependence (Disease Ontology:DOID:0050741); late onset Parkinson's disease (Disease Ontology:DOID:0060892); AMED syndrome (Disease Ontology:DOID:0080952); cholestasis (Disease Ontology:DOID:13580); Parkinson's disease (Disease Ontology:DOID:14330); alcohol use disorder (Disease Ontology:DOID:1574); pancreatic cancer (Disease Ontology:DOID:1793); asthma (Disease Ontology:DOID:2841)", "pathway": " (dme:Dmel_CG6598); (R-DME-211935); (R-DME-2161541); (R-DME-5365859); (R-DME-71384)", "pathway_count": 5, "publication_count": 5, "publication_id_list": "10731132;12537569;12537572;7957234;8197167", "class_list": "", "function": "Class-III ADH is remarkably ineffective in oxidizing ethanol, but it readily catalyzes the oxidation of long-chain primary alcohols and the oxidation of S-(hydroxymethyl) glutathione., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 8, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9VGV2", "ec_number_list": "1.1.1.1;1.1.1.-;1.1.1.284;1.1.1.73", "go_molecular_function": "GO:0004022 alcohol dehydrogenase (NAD+) activity;GO:0008270 zinc ion binding;GO:0051903 S-(hydroxymethyl)glutathione dehydrogenase [NAD(P)+] activity;GO:0004552 octanol dehydrogenase (NAD+) activity;GO:0080007 S-nitrosoglutathione reductase (NADH) activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0008542 visual learning;GO:0046294 formaldehyde catabolic process;GO:0006066 alcohol metabolic process;GO:0080164 regulation of nitric oxide metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P46415-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P46863-1", "uniprot_id": "KL61_DROME", "mass": 121163.0, "length": 1066, "protein_name": "Kinesin-like protein Klp61F", "gene_name": "Klp61F", "organism": "Fruit fly", "refseq_name": "Kinesin-like protein at 61F", "refseq_ac": "NP_476818", "gene_names_uniprotkb": "Klp61F; CG9191; KLP2", "gene_names_refseq": "6345; CG9191-PA; CG9191; DmKLP61F; DmKRP130; DmKlp61F; Dmel\\CG9191; KIF 8; KIF11; KLP2; KLP61F; KLP61f; KLP61; KRP130; KRP[[(130)]]; KRP[[130]]; Kin-5; Kin5; Klp 61F; Klp2; Klp61F/KRP130; Klp61F; Klp61f; Krp130; klp61F; klp61f; l(3)07012; l(3)6D283; l(3)Klp61F; urcn; urc", "protein_names_uniprotkb": "Kinesin-like protein Klp61F; Bipolar kinesin KRP-130", "protein_names_refseq": "CG9191-PA; Kinesin-like protein at 61F; Kinesin-related protein-130kD; Kinesin8B; Klp61F-PA; kinesin-5 motor; kinesin-5s; kinesin-5; kinesin-like protein; urchin", "tax_id": 7227, "disease": "microcephaly with or without chorioretinopathy, lymphedema, or mental retardation (Disease Ontology:DOID:0060349)", "pathway": " (dme:Dmel_CG9191); (R-DME-983189)", "pathway_count": 2, "publication_count": 19, "publication_id_list": "10469596;10731132;12537569;12537572;17372656;18327897;18678711;19062285;19158379;1924306;19285086;19800237;23857769;24714498;8227131;8538794;8589456;8918872;9885249", "class_list": "", "function": "Important role in mitotic dividing cells (PubMed:8227131). Microtubule motor required for spindle body separation (PubMed:8918872). Slow plus-end directed microtubule motor capable of cross-linking and sliding apart antiparallel microtubules, thereby pushing apart the associated spindle poles during spindle assembly and function (PubMed:19062285, PubMed:8589456, PubMed:8918872). Forms cross-links between microtubules within interpolar microtubule bundles (PubMed:19158379, PubMed:9885249). Contributes to the length of the metaphase spindle, maintains the prometaphase spindle by antagonizing Ncd, drives anaphase B, and also contributes to normal chromosome congression, kinetochore spacing, and anaphase A rates (PubMed:19158379). Displays microtubule-stimulated ATPase activity (PubMed:8589456). Required for normal fusome organization (PubMed:10469596). Required in non-mitotic cells for transport of secretory proteins from the Golgi complex to the cell surface (PubMed:23857769)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 7, "reported_mutagensis": 10, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q8T0A6;Q9W0I8", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0008017 microtubule binding;GO:0008574 plus-end-directed microtubule motor activity;GO:0003774 cytoskeletal motor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0005819 spindle", "go_biological_process": "GO:0000278 mitotic cell cycle;GO:0051301 cell division;GO:0090307 mitotic spindle assembly;GO:0042998 positive regulation of Golgi to plasma membrane protein transport;GO:0007018 microtubule-based movement", "synthesized_glycan_count": 0, "hit_score": 2.0, "record_id": "P46863-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P48596-1", "uniprot_id": "GCH1_DROME", "mass": 35541.0, "length": 324, "protein_name": "GTP cyclohydrolase 1", "gene_name": "Pu", "organism": "Fruit fly", "refseq_name": "punch, isoform C", "refseq_ac": "NP_523801", "gene_names_uniprotkb": "Pu; CG9441", "gene_names_refseq": "CG9441; DGTPCH; Dmel\\CG9441; GCH1; GTPCH; GTPC; Gch1; Gr; Pu; l(2)57Cf; p[Gr]; upi", "protein_names_uniprotkb": "GTP cyclohydrolase 1; 3.5.4.16; GTP cyclohydrolase I; GTP-CH-I; Protein punch", "protein_names_refseq": "CG9441-PC; GTP cyclohydrolase I isoform c; GTP cyclohydrolase; Pu-PC; grape; punch, isoform C; punch; unpigmented", "tax_id": 7227, "disease": "Parkinsonism (Disease Ontology:DOID:0080855); dopa-responsive dystonia (Disease Ontology:DOID:0090043); BH4-deficient hyperphenylalaninemia B (Disease Ontology:DOID:0112225); portal hypertension (Disease Ontology:DOID:10762); hypertension (Disease Ontology:DOID:10763); sickle cell anemia (Disease Ontology:DOID:10923); sciatic neuropathy (Disease Ontology:DOID:11446); diabetic angiopathy (Disease Ontology:DOID:11713); primary biliary cholangitis (Disease Ontology:DOID:12236); dilated cardiomyopathy (Disease Ontology:DOID:12930); transient cerebral ischemia (Disease Ontology:DOID:224); bipolar disorder (Disease Ontology:DOID:3312); middle cerebral artery infarction (Disease Ontology:DOID:3525); cerebral infarction (Disease Ontology:DOID:3526); pulmonary fibrosis (Disease Ontology:DOID:3770); liver cirrhosis (Disease Ontology:DOID:5082); intestinal disease (Disease Ontology:DOID:5295); dystonia (Disease Ontology:DOID:543); myocardial infarction (Disease Ontology:DOID:5844); congestive heart failure (Disease Ontology:DOID:6000); type 2 diabetes mellitus (Disease Ontology:DOID:9352)", "pathway": " (dme:Dmel_CG9441); (R-DME-1474151)", "pathway_count": 2, "publication_count": 5, "publication_id_list": "10731132;12537569;12537572;3080426;8262960", "class_list": "", "function": "Isoform B is required for eye pigment production, Isoform C may be required for normal embryonic development and segment pattern formation., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 21, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q6TY66;Q6TY71;Q6TY73;Q6TY74;Q6TY78;Q960S4;Q9W2J9;Q9W2K1;Q9Y0C8", "ec_number_list": "3.5.4.16", "go_molecular_function": "GO:0005525 GTP binding;GO:0008270 zinc ion binding;GO:0003934 GTP cyclohydrolase I activity;GO:0060308 GTP cyclohydrolase I regulator activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0046654 tetrahydrofolate biosynthetic process;GO:0006729 tetrahydrobiopterin biosynthetic process;GO:0009880 embryonic pattern specification;GO:0048067 cuticle pigmentation;GO:0006728 pteridine biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P48596-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P48609-1", "uniprot_id": "CDK5_DROME", "mass": 33180.0, "length": 294, "protein_name": "Cyclin-dependent kinase 5 homolog", "gene_name": "Cdk5", "organism": "Fruit fly", "refseq_name": "Cyclin-dependent kinase 5", "refseq_ac": "NP_477080", "gene_names_uniprotkb": "Cdk5; CG8203", "gene_names_refseq": "CDK5; CG8203; Cdk5; DmCdk5; Dmel\\CG8203; cdk5", "protein_names_uniprotkb": "Cyclin-dependent kinase 5 homolog; 2.7.11.22; Cell division protein kinase 5", "protein_names_refseq": "CG8203-PA; Cdk5-PA; Cyclin-dependent kinase 5", "tax_id": 7227, "disease": "lissencephaly (Disease Ontology:DOID:0050453); lissencephaly 7 with cerebellar hypoplasia (Disease Ontology:DOID:0112231); Alzheimer's disease (Disease Ontology:DOID:10652); trigeminal neuralgia (Disease Ontology:DOID:12098); depressive disorder (Disease Ontology:DOID:1596); epilepsy (Disease Ontology:DOID:1826); transient cerebral ischemia (Disease Ontology:DOID:224); brain ischemia (Disease Ontology:DOID:2316); vascular dementia (Disease Ontology:DOID:8725)", "pathway": " (dme:Dmel_CG8203); (R-DME-6804756); (R-DME-9841922)", "pathway_count": 3, "publication_count": 6, "publication_id_list": "10731132;12537569;12537572;30217452;7805863;8930898", "class_list": "", "function": "Probably involved in the control of the cell cycle. Interacts with D1 and D3-type G1 cyclins. Possible regulator of neuronal differentiation and/or development (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 9, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q94878;Q9V7D8", "ec_number_list": "2.7.11.17;2.7.11.1;2.7.11.13;2.7.11.24;2.3.1.48;2.7.11.22;2.7.11.21;5.6.1.8;2.7.11.11;2.7.11.23;2.7.12.1;2.7.11.25;2.7.11.12;2.7.12.2;3.5.1.98;2.7.10.2;2.3.1.286;2.7.11.39", "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0004693 cyclin-dependent protein serine/threonine kinase activity;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0016533 protein kinase 5 complex;GO:0000307 cyclin-dependent protein kinase holoenzyme complex", "go_biological_process": "GO:0007409 axonogenesis;GO:0008344 adult locomotory behavior;GO:0051301 cell division;GO:0051402 neuron apoptotic process;GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P48609-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P49258-1", "uniprot_id": "CALL_DROME", "mass": 17015.0, "length": 148, "protein_name": "Calmodulin-related protein 97A", "gene_name": "Acam", "organism": "Fruit fly", "refseq_name": "androcam, isoform B", "refseq_ac": "NP_001163737", "gene_names_uniprotkb": "Acam; And; CG17769; Camr97A", "gene_names_refseq": "ACaM; Acam; And; CG17769; CalB; Camr97A; Dmel\\CG17769", "protein_names_uniprotkb": "Calmodulin-related protein 97A; Protein androcam", "protein_names_refseq": "Acam-PB; CG17769-PB; Calmodulin-related 97A; androcalmodulin; androcam, isoform B; androcam", "tax_id": 7227, "disease": "cancer (Disease Ontology:DOID:162)", "pathway": " (dme:Dmel_CG17769); (R-DME-6798695)", "pathway_count": 2, "publication_count": 4, "publication_id_list": "10731132;12537569;12537572;7980384", "class_list": "", "function": "May be involved in calcium-mediated signal transduction., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "E1JIY2;Q9VBL9", "ec_number_list": "", "go_molecular_function": "GO:0005509 calcium ion binding;GO:0030234 enzyme regulator activity;GO:0070855 myosin VI head/neck binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0031476 myosin VI complex;GO:0070865 investment cone", "go_biological_process": "GO:0030048 actin filament-based movement;GO:0000226 microtubule cytoskeleton organization", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P49258-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P49866-1", "uniprot_id": "HNF4_DROME", "mass": 76388.0, "length": 704, "protein_name": "Transcription factor HNF-4 homolog", "gene_name": "Hnf4", "organism": "Fruit fly", "refseq_name": "hepatocyte nuclear factor 4, isoform D", "refseq_ac": "NP_001097126", "gene_names_uniprotkb": "Hnf4; CG9310; DmHNF4; Dmel\\CG9310; Dmel_CG9310; HNF-4(D); HNF-4; HNF4alpha; HNF4; Hnf-4h; Hnf-4; NHF4; NR2A4; dHNF-4; dHNF4; dHnf4; hnf4", "gene_names_refseq": "CG9310; DmHNF4; Dmel\\CG9310; HNF-4(D); HNF-4; HNF4alpha; HNF4; Hnf-4h; Hnf-4; Hnf4; NHF4; NR2A4; dHNF-4; dHNF4; dHnf4; hnf4", "protein_names_uniprotkb": "Transcription factor HNF-4 homolog; Nuclear receptor subfamily 2 group A member 4; dHNF4", "protein_names_refseq": "CG9310-PD; Hnf4-PD; hepatocyte nuclear factor 4 homologue; hepatocyte nuclear factor 4, isoform D", "tax_id": 7227, "disease": "maturity-onset diabetes of the young (Disease Ontology:DOID:0050524); Fanconi renotubular syndrome 4 (Disease Ontology:DOID:0080760); maturity-onset diabetes of the young type 1 (Disease Ontology:DOID:0111099); Fanconi syndrome (Disease Ontology:DOID:1062); familial combined hyperlipidemia (Disease Ontology:DOID:13809); glaucoma (Disease Ontology:DOID:1686); liver cirrhosis (Disease Ontology:DOID:5082); hepatocellular carcinoma (Disease Ontology:DOID:684); type 2 diabetes mellitus (Disease Ontology:DOID:9352); hypoglycemia (Disease Ontology:DOID:9993)", "pathway": " (dme:Dmel_CG9310); (R-DME-383280)", "pathway_count": 2, "publication_count": 13, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;19254568;25589440;26109356;26109357;8440243", "class_list": "", "function": "Transcriptionally controlled transcription factor. Important for the differentiation of various specialized cell types that arise from both endoderm and mesoderm. May have a role in early gut formation. Plays an essential role in lipid catabolism, regulating lipid mobilization and beta-oxidation in response to nutrient deprivation., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 10, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A8DYX8;C5WLN3;Q8IGG2;Q8IPF2;Q9VLI7;Q9VLI8", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0003707 nuclear steroid receptor activity;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0004879 nuclear receptor activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0034440 lipid oxidation;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0030154 cell differentiation;GO:0032869 cellular response to insulin stimulus", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "P49866-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P52029-1", "uniprot_id": "G6PI_DROME", "mass": 62339.0, "length": 558, "protein_name": "Glucose-6-phosphate isomerase", "gene_name": "Pgi", "organism": "Fruit fly", "refseq_name": "phosphoglucose isomerase, isoform A", "refseq_ac": "NP_523663", "gene_names_uniprotkb": "Pgi; CG8251", "gene_names_refseq": "CG8251; DmG6PI; Dmel\\CG8251; GPI; Gpi; PGI; Pgi; gpi; pgi", "protein_names_uniprotkb": "Glucose-6-phosphate isomerase; 5.3.1.9; GPI; PGI; PHI; Phosphoglucose isomerase; Phosphohexose isomerase", "protein_names_refseq": "CG8251-PA; Glucose-6-phosphate isomerase; Pgi-PA; glucose phosphate isomerase; phosphoglucoisomerase; phosphoglucose isomerase, isoform A; phosphoglucose isomerase", "tax_id": 7227, "disease": "congenital nonspherocytic hemolytic anemia 4 (Disease Ontology:DOID:0051005); intellectual disability (Disease Ontology:DOID:1059); heart disease (Disease Ontology:DOID:114); Parkinson's disease (Disease Ontology:DOID:14330); congenital nonspherocytic hemolytic anemia (Disease Ontology:DOID:2861); neuromuscular disease (Disease Ontology:DOID:440); congenital hemolytic anemia (Disease Ontology:DOID:589); acute myeloid leukemia (Disease Ontology:DOID:9119); acute lymphoblastic leukemia (Disease Ontology:DOID:9952)", "pathway": " (dme:Dmel_CG8251); (R-DME-5628897); (R-DME-6798695); (R-DME-70171); (R-DME-70263)", "pathway_count": 5, "publication_count": 3, "publication_id_list": "10731132;12537569;12537572", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 9, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A4UZ93;Q0E9F0;Q27868;Q27870;Q9V4Z8", "ec_number_list": "2.4.1.186;5.4.2.7;5.4.2.-;3.2.1.31;1.1.1.42;2.4.2.1;2.7.11.24;2.7.1.40;4.1.2.13;2.7.4.6;2.4.2.7;3.6.5.-;1.11.1.6;5.3.1.9;2.7.1.11;1.1.1.205;3.4.22.-;3.6.4.12;3.6.4.6;1.16.3.1;2.7.1.35;2.3.2.5;3.4.24.-;2.3.2.27;2.7.1.1;5.2.1.8;3.4.19.-;1.11.1.24;5.6.1.5;5.4.2.11;5.4.2.4;3.2.1.23;3.6.1.5;3.6.4.13;3.3.2.6;3.5.4.5;2.7.11.22;2.7.11.23;4.2.1.24;5.4.2.2;3.4.-.-;1.11.2.-;2.4.1.25;3.2.1.33;2.7.1.-;3.5.4.6;2.3.2.26", "go_molecular_function": "GO:0004347 glucose-6-phosphate isomerase activity;GO:0097367 carbohydrate derivative binding;GO:0048029 monosaccharide binding", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0006094 gluconeogenesis;GO:0042593 glucose homeostasis;GO:0006096 glycolytic process;GO:0061621 canonical glycolysis;GO:0006002 fructose 6-phosphate metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "P52029-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P53501-1", "uniprot_id": "ACT3_DROME", "mass": 41835.0, "length": 376, "protein_name": "Actin-57B", "gene_name": "Act57B", "organism": "Fruit fly", "refseq_name": "actin 57B", "refseq_ac": "NP_523800", "gene_names_uniprotkb": "Act57B; CG10067", "gene_names_refseq": "ACT3; Act57A; Act57B; Act57b; Act57; Actin-57B; Actin; ArpE; BEST:RE38067; CG10067; CG30294; C; Dmel\\CG10067; M; T10; act 57A; act57A; act57B; act57b; actin-57B; actin; anon-EST:CL2c12; chr2R:16452771..16452966", "protein_names_uniprotkb": "Actin-57B; 3.6.4.-", "protein_names_refseq": "Act57B-PA; Actin-57B; CG10067-PA; F-actin; actin 57B; actin57B", "tax_id": 7227, "disease": "metabolic dysfunction-associated steatotic liver disease (Disease Ontology:DOID:0080208); Baraitser-Winter syndrome 1 (Disease Ontology:DOID:0081112); Baraitser-Winter syndrome 2 (Disease Ontology:DOID:0081113); hypertrophic cardiomyopathy 11 (Disease Ontology:DOID:0110317); autosomal dominant nonsyndromic deafness 20 (Disease Ontology:DOID:0110550); intestinal atresia (Disease Ontology:DOID:10486); hand, foot and mouth disease (Disease Ontology:DOID:10881); hypertrophic cardiomyopathy (Disease Ontology:DOID:11984); Moyamoya disease (Disease Ontology:DOID:13099); patent ductus arteriosus (Disease Ontology:DOID:13832); thoracic aortic aneurysm (Disease Ontology:DOID:14004); thrombocytopenia (Disease Ontology:DOID:1588); temporal lobe epilepsy (Disease Ontology:DOID:3328)", "pathway": " (dme:Dmel_CG10067); (R-DME-114608); (R-DME-9035034)", "pathway_count": 3, "publication_count": 6, "publication_id_list": "10731132;12537572;22116028;30526847;6263481;9344535", "class_list": "", "function": "Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells., [UniProtKB]; Multiple isoforms are involved in various cellular functions such as cytoskeleton structure, cell mobility, chromosome movement and muscle contraction., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 13, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9W2Q0", "ec_number_list": "3.6.4.13;7.2.2.-;3.6.4.-;3.6.5.2;3.6.4.10;3.6.4.6;3.6.4.12;5.6.2.4;5.6.2.5;1.15.1.1;2.7.4.3;5.6.2.3;3.1.-.-;3.6.1.15;3.1.3.95;3.-.-.-;5.6.1.1;2.7.11.1;3.6.-.-;5.6.2.-", "go_molecular_function": "GO:0005200 structural constituent of cytoskeleton;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0015629 actin cytoskeleton", "go_biological_process": "GO:0000281 mitotic cytokinesis;GO:0050807 regulation of synapse organization;GO:0030723 ovarian fusome organization", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P53501-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P53624-1", "uniprot_id": "MA1A1_DROME", "mass": 74966.0, "length": 667, "protein_name": "Mannosyl-oligosaccharide alpha-1,2-mannosidase IA", "gene_name": "alpha-Man-Ia", "organism": "Fruit fly", "refseq_name": "alpha-Mannosidase class I a, isoform P", "refseq_ac": "NP_001259402", "gene_names_uniprotkb": "alpha-Man-Ia; CG17809; CG18799; CG32682; CG32684; CG42275; DM-GI; Dmel\\CG42275; Dmel_CG42275; MA12; MAN-1; Man'ase; ManI; a-Man-Ia; alpha-Man-1; alpha-Man-I; alpha-Man-la; alpha-Man-l; alpha-man-1; alphaMan1a; dManI; dMas-1; mas-1; mas1", "gene_names_refseq": "CG17809; CG18799; CG32682; CG32684; CG42275; DM-GI; Dmel\\CG42275; MA12; MAN-1; Man'ase; ManI; a-Man-Ia; alpha-Man-1; alpha-Man-Ia; alpha-Man-I; alpha-Man-la; alpha-Man-l; alphaMan1a; dManI; dMas-1; mas-1; mas1", "protein_names_uniprotkb": "Mannosyl-oligosaccharide alpha-1,2-mannosidase IA; 3.2.1.113; Man(9)-alpha-mannosidase; Mannosidase-1", "protein_names_refseq": "CG42275-PP; alpha 1,2 mannosidase; alpha mannosidase I; alpha-1,2-mannosidase I; alpha-D-mannosidase; alpha-Man-Ia-PP; alpha-Mannosidase class I a, isoform P; alpha-mannosidase; alpha1,2-,mannosidase; mannosidase 1", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG42275); (R-DME-964827)", "pathway_count": 2, "publication_count": 12, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357;7729592", "class_list": "", "function": "Involved in the maturation of Asn-linked oligosaccharides. Progressively trim alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce Man(5)GlcNAc(2)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A4V480;M9PH54;P53625;Q9W2W6;Q9W2W7", "ec_number_list": "3.2.1.-;3.2.1.113", "go_molecular_function": "GO:0005509 calcium ion binding;GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005783 endoplasmic reticulum;GO:0012505 endomembrane system;GO:0016020 membrane", "go_biological_process": "GO:0005975 carbohydrate metabolic process;GO:0036503 ERAD pathway;GO:1904381 Golgi apparatus N-glycan mannose trimming", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "P53624-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P54269-1", "uniprot_id": "CAUP_DROME", "mass": 73668.0, "length": 693, "protein_name": "Homeobox protein caupolican", "gene_name": "caup", "organism": "Fruit fly", "refseq_name": "caupolican", "refseq_ac": "NP_524046", "gene_names_uniprotkb": "caup; CG10605", "gene_names_refseq": "CG10605; Caup; Dmel\\CG10605; IRO-C; Iro-C; IroC; Iro; caup; iro-C; iro", "protein_names_uniprotkb": "Homeobox protein caupolican", "protein_names_refseq": "CG10605-PA; caup-PA; cauplican; caupolican; iroquis complex; iroquois gene complex; iroquois-complex", "tax_id": 7227, "disease": "congestive heart failure (Disease Ontology:DOID:6000)", "pathway": " (dme:Dmel_CG10605)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "10731132;12537569;12537572;8620542", "class_list": "", "function": "Controls proneural and vein forming genes. Positive transcriptional controller of ac-sc (achaete-scute). May act as an activator that interacts with the transcriptional complex assembled on the ac and sc promoters and participates in transcription initiation., [UniProtKB, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "Q5BIH8;Q5U1A6;Q8MR03;Q9VU00", "ec_number_list": "", "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0007346 regulation of mitotic cell cycle;GO:0030182 neuron differentiation", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P54269-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P54352-2", "uniprot_id": "EAS_DROME", "mass": 56842.0, "length": 495, "protein_name": "Ethanolamine kinase", "gene_name": "eas", "organism": "Fruit fly", "refseq_name": "easily shocked, isoform F", "refseq_ac": "NP_001245706", "gene_names_uniprotkb": "eas; CG3525", "gene_names_refseq": "CG3525; Dmel\\CG3525; EP770; EtnK; PC80; RE10142; RH11; ala; eas", "protein_names_uniprotkb": "Ethanolamine kinase; 2.7.1.82; EK; Protein easily shocked", "protein_names_refseq": "CG3525-PF; alpha lobes absent; alpha-lobe absent; eas-PF; easily shocked, isoform F; easily shocked; easily-shocked; ethanolamine kinase", "tax_id": 7227, "disease": "heart conduction disease (Disease Ontology:DOID:10273); epilepsy (Disease Ontology:DOID:1826)", "pathway": " (dme:Dmel_CG3525); (R-DME-1483213)", "pathway_count": 2, "publication_count": 6, "publication_id_list": "10731132;12537569;12537572;17372656;18327897;7923374", "class_list": "", "function": "Highly specific for ethanolamine phosphorylation. May be a rate-controlling step in phosphatidylethanolamine biosynthesis., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "C8VV66;M9NEJ9;M9NGH8;Q1RL01;Q540Y9;Q86B51;Q8IR20;Q9VXI7;X2JFQ7", "ec_number_list": "2.7.1.82", "go_molecular_function": "GO:0005524 ATP binding;GO:0004103 choline kinase activity;GO:0004305 ethanolamine kinase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0046959 habituation;GO:0007638 mechanosensory behavior;GO:0008306 associative learning;GO:0001666 response to hypoxia;GO:0007420 brain development", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P54352-2", "record_type": "protein" }, { "uniprot_canonical_ac": "P54353-1", "uniprot_id": "DOD_DROME", "mass": 18377.0, "length": 166, "protein_name": "Putative peptidyl-prolyl cis-trans isomerase dodo", "gene_name": "dod", "organism": "Fruit fly", "refseq_name": "dodo", "refseq_ac": "NP_523428", "gene_names_uniprotkb": "dod; CG17051", "gene_names_refseq": "CG17051; Dmel\\CG17051; Pin1; dod", "protein_names_uniprotkb": "Putative peptidyl-prolyl cis-trans isomerase dodo; 5.2.1.8; PPIase dodo; Rotamase dodo", "protein_names_refseq": "CG17051-PA; dod-PA; dodo; drosophila pin1", "tax_id": 7227, "disease": "Alzheimer's disease (Disease Ontology:DOID:10652); secondary hyperparathyroidism (Disease Ontology:DOID:12466); asthma (Disease Ontology:DOID:2841)", "pathway": " (dme:Dmel_CG17051); (R-DME-6804756); (R-DME-6811555)", "pathway_count": 3, "publication_count": 4, "publication_id_list": "10731132;12537572;8552658;9520435", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "C6TP71;O61344;Q9VRH1", "ec_number_list": "5.2.1.8;2.7.11.1", "go_molecular_function": "GO:0003755 peptidyl-prolyl cis-trans isomerase activity;GO:0140297 DNA-binding transcription factor binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol", "go_biological_process": "GO:1904059 regulation of locomotor rhythm;GO:0031398 positive regulation of protein ubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P54353-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P54358-1", "uniprot_id": "DPOD1_DROME", "mass": 124905.0, "length": 1092, "protein_name": "DNA polymerase delta catalytic subunit", "gene_name": "PolD1", "organism": "Fruit fly", "refseq_name": "DNA polymerase delta subunit 1", "refseq_ac": "NP_524099", "gene_names_uniprotkb": "PolD1; CG5949; DNApol-delta; DNApolD1; PolD", "gene_names_refseq": "5949; CAA61369; CG5949; DNA Pol Delta; DNA pol delta; DNApol-delta; Dm Poldelta; Dmel\\CG5949; Pol delta125; PolD1; Poldelta 125KDa; Poldelta125KDa; Poldelta; dnapol delta; l(3)72Ac; polD", "protein_names_uniprotkb": "DNA polymerase delta catalytic subunit; 2.7.7.7; 3'-5' exodeoxyribonuclease; 3.1.11.-", "protein_names_refseq": "CG5949-PA; DNA polymerase delta subunit 1; DNA polymerase delta; DNA polymerase-delta; DNA-polymerase-delta; DNApol-delta; PolD1-PA; lethal (3) 72Ac", "tax_id": 7227, "disease": "immunodeficiency 120 (Disease Ontology:DOID:0061086); colorectal cancer (Disease Ontology:DOID:9256)", "pathway": " (dme:Dmel_CG5949); (R-DME-69166); (R-DME-69183)", "pathway_count": 3, "publication_count": 9, "publication_id_list": "10731132;12537569;12537572;1360647;17087725;31100062;7907087;8415662;8543168", "class_list": "", "function": "As the catalytic component of the DNA polymerase delta complex, plays a crucial role in high fidelity genome replication, including lagging strand synthesis, DNA recombination and repair (By similarity). Exhibits both DNA polymerase and 3'- to 5'-exonuclease activities (PubMed:1360647, PubMed:7907087, PubMed:8415662). Required at the nucleus of rapidly dividing embryonic cells to activate genome replication during the earliest cell cycles (PubMed:31100062). Likely to require the presence of accessory proteins PolD2 and PolD3 for full activity (PubMed:31100062)., [UniProtKB, UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9VUW8", "ec_number_list": "2.7.7.7;3.1.11.-;2.7.7.-;3.1.-.-;3.6.4.12", "go_molecular_function": "GO:0003887 DNA-directed DNA polymerase activity;GO:0008296 3'-5'-DNA exonuclease activity;GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0051539 4 iron, 4 sulfur cluster binding", "go_cellular_component": "GO:0043625 delta DNA polymerase complex;GO:0005634 nucleus;GO:0005654 nucleoplasm", "go_biological_process": "GO:0006297 nucleotide-excision repair, DNA gap filling;GO:0006287 base-excision repair, gap-filling;GO:0045004 DNA replication proofreading;GO:0006261 DNA-templated DNA replication", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P54358-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P54360-1", "uniprot_id": "FOJO_DROME", "mass": 65490.0, "length": 583, "protein_name": "Extracellular serine/threonine protein kinase four-jointed", "gene_name": "fj", "organism": "Fruit fly", "refseq_name": "four-jointed", "refseq_ac": "NP_477483", "gene_names_uniprotkb": "fj; CG10917", "gene_names_refseq": "CG10917; Dmel\\CG10917; FJ; Fjx1; Fj; fj", "protein_names_uniprotkb": "Extracellular serine/threonine protein kinase four-jointed; 2.7.11.1", "protein_names_refseq": "CG10917-PA; fj-PA; four jointed; four-jointed", "tax_id": 7227, "disease": "obesity (Disease Ontology:DOID:9970)", "pathway": " (dme:Dmel_CG10917)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "10607560;10731132;11566858;12537569;12537572;14757640;18635802;7555705;8606003", "class_list": "", "function": "Golgi serine/threonine protein kinase required for intermediate growth in the proximal-distal axis. Phosphorylates specific residues within extracellular cadherin domains of Fat (ft) and Dachsous (ds) as they transit through the Golgi (PubMed:18635802). Acts in ommatidial polarity determination as a secondary signal downstream of Notch, JAK/STAT and wingless. Also necessary for the initiation, up-regulation or maintenance of Notch ligand, Serrate (Ser) expression in legs, thereby participating in a feedback loop with N signaling. Sufficient for joint formation and growth in the leg (PubMed:10607560, PubMed:11566858, PubMed:14757640, PubMed:7555705, PubMed:8606003)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 4, "predicted_n_glycosites": 3, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "Q24176;Q8SZ37;Q9V8E3", "ec_number_list": "2.7.11.17;2.7.11.1;2.7.11.13;2.7.11.24;2.7.11.22;2.7.11.21;5.6.1.8;2.7.11.11;2.7.11.23;2.7.12.1;2.7.11.25;2.7.11.12;2.7.12.2;2.7.10.2;2.7.11.39", "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0017147 Wnt-protein binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005576 extracellular region;GO:0005737 cytoplasm;GO:0005886 plasma membrane", "go_biological_process": "GO:0006468 protein phosphorylation;GO:0007219 Notch signaling pathway;GO:0007267 cell-cell signaling;GO:0016055 Wnt signaling pathway;GO:0043393 regulation of protein binding", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P54360-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P54397-1", "uniprot_id": "FKB39_DROME", "mass": 39344.0, "length": 357, "protein_name": "39 kDa FK506-binding nuclear protein", "gene_name": "Fkbp39", "organism": "Fruit fly", "refseq_name": "FK506-binding protein 39kD", "refseq_ac": "NP_524364", "gene_names_uniprotkb": "Fkbp39; CG6226; FK506-bp1", "gene_names_refseq": "CG6226; Dmel\\CG6226; FK506-bp1; FK506bp1; FKBP39; FKbp39; Fkbp39; IFK506-bp1; fkbp39", "protein_names_uniprotkb": "39 kDa FK506-binding nuclear protein; 5.2.1.8; PPIase; Peptidyl-prolyl cis-trans isomerase; Rotamase", "protein_names_refseq": "CG6226-PA; FK506 binding protein-1; FK506-binding protein 1; FK506-binding protein 39kD; FK506-binding protein of 39 kDa; Fkbp39-PA", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG6226)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "10731132;12537569;12537572;17372656;18327897;7538962", "class_list": "", "function": "PPIases accelerate the folding of proteins. May function in a signal transduction cascade during early development., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9VF88", "ec_number_list": "5.2.1.8", "go_molecular_function": "GO:0003690 double-stranded DNA binding;GO:0005528 FK506 binding;GO:0003755 peptidyl-prolyl cis-trans isomerase activity;GO:0070594 juvenile hormone response element binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005730 nucleolus;GO:0000785 chromatin;GO:0000792 heterochromatin", "go_biological_process": "GO:0010507 negative regulation of autophagy;GO:0016242 negative regulation of macroautophagy;GO:0035626 juvenile hormone mediated signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P54397-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P56544-1", "uniprot_id": "ACYP1_DROME", "mass": 13697.0, "length": 120, "protein_name": "Acylphosphatase-1", "gene_name": "Acyp", "organism": "Fruit fly", "refseq_name": "acylphosphatase, isoform B", "refseq_ac": "NP_001285916", "gene_names_uniprotkb": "Acyp; ACPDro; AcPDro; AcP; BG:DS00180.1; CG16870; Dmel\\CG16870; Dmel_CG16870", "gene_names_refseq": "ACPDro; AcPDro; Acyp; BG:DS00180.1; CG16870; Dmel\\CG16870", "protein_names_uniprotkb": "Acylphosphatase-1; 3.6.1.7; AcPDro; Acylphosphate phosphohydrolase 1", "protein_names_refseq": "Acyp-PB; CG16870-PB; acylphosphatase, isoform B; acylphosphatase", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG16870)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "10471707;10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357;9744795", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9V3K1", "ec_number_list": "3.6.1.7", "go_molecular_function": "GO:0003998 acylphosphatase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "P56544-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P58950-1", "uniprot_id": "GR10A_DROME", "mass": 48392.0, "length": 408, "protein_name": "Gustatory receptor 10a", "gene_name": "Gr10a", "organism": "Fruit fly", "refseq_name": "gustatory receptor 10a", "refseq_ac": "NP_727523", "gene_names_uniprotkb": "Gr10a; CG32664", "gene_names_refseq": "CG32664; Dmel\\CG32664; GR10a; Gr10B1; Gr10a; gr10a", "protein_names_uniprotkb": "Gustatory receptor 10a", "protein_names_refseq": "CG32664-PB; Gr10a-PB; gustatory receptor 10B1; gustatory receptor 10a", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG32664)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "10731132;11257221;11516643;12537572;17167414;22031876", "class_list": "", "function": "Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A1C3K6", "ec_number_list": "", "go_molecular_function": "GO:0015276 ligand-gated monoatomic ion channel activity;GO:0008527 taste receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane;GO:0030424 axon;GO:0030425 dendrite;GO:0043025 neuronal cell body", "go_biological_process": "GO:0007165 signal transduction;GO:0034220 monoatomic ion transmembrane transport;GO:0050909 sensory perception of taste", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P58950-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P58952-1", "uniprot_id": "GR22C_DROME", "mass": 44407.0, "length": 383, "protein_name": "Putative gustatory receptor 22c", "gene_name": "Gr22c", "organism": "Fruit fly", "refseq_name": "gustatory receptor 22c", "refseq_ac": "NP_722732", "gene_names_uniprotkb": "Gr22c; CG31929", "gene_names_refseq": "CG31929; Dmel\\CG31929; GR22c; GRLU.6; Gr22c; Gr2940.3; GrLU6; LU.6", "protein_names_uniprotkb": "Putative gustatory receptor 22c", "protein_names_refseq": "CG31929-PA; Gr22c-PA; gustatory receptor 22c; gustatory receptor 2940.3; gustatory receptor LU.6", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG31929)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "10731132;11516643;12537572;15210117", "class_list": "", "function": "Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0015276 ligand-gated monoatomic ion channel activity;GO:0008527 taste receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane;GO:0030424 axon;GO:0030425 dendrite;GO:0043025 neuronal cell body", "go_biological_process": "GO:0007165 signal transduction;GO:0034220 monoatomic ion transmembrane transport;GO:0050909 sensory perception of taste", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P58952-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P58954-1", "uniprot_id": "GR22F_DROME", "mass": 44422.0, "length": 378, "protein_name": "Putative gustatory receptor 22f", "gene_name": "Gr22f", "organism": "Fruit fly", "refseq_name": "gustatory receptor 22f", "refseq_ac": "NP_722729", "gene_names_uniprotkb": "Gr22f; CG31932", "gene_names_refseq": "22B.1; CG31932; Dmel\\CG31932; GR22B.1; GR22b1; GR22f; Gr22B1; Gr22f", "protein_names_uniprotkb": "Putative gustatory receptor 22f", "protein_names_refseq": "CG31932-PA; Gr22f-PA; gustatory receptor 22B.1; gustatory receptor 22f", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG31932)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "10731132;11516643;12537572;15202999", "class_list": "", "function": "Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0015276 ligand-gated monoatomic ion channel activity;GO:0008527 taste receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane;GO:0030424 axon;GO:0030425 dendrite;GO:0043025 neuronal cell body", "go_biological_process": "GO:0007165 signal transduction;GO:0034220 monoatomic ion transmembrane transport;GO:0050909 sensory perception of taste", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P58954-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P58957-1", "uniprot_id": "G39AB_DROME", "mass": 44517.0, "length": 381, "protein_name": "Gustatory and pheromone receptor 39a, isoform C", "gene_name": "Gr39a", "organism": "Fruit fly", "refseq_name": "gustatory receptor 39a, isoform C", "refseq_ac": "NP_724330", "gene_names_uniprotkb": "Gr39a; CG31622; GR39D.2", "gene_names_refseq": "39D.2a; 39D.2b; 39D.2c; 39D.2d; 39D.2; 39D2a; 39D2b; 39D2c; 39D2d; CG31622; Dmel\\CG31622; GR39D.2; GR39a; Gr39D2A; Gr39D2a; Gr39D2b; Gr39D2c; Gr39D2d; Gr39a.a; Gr39a.b; Gr39a.c; Gr39a.d; Gr39aA; Gr39aB; Gr39aC; Gr39aD; Gr39a; gene Y; l(2)k05106", "protein_names_uniprotkb": "Gustatory and pheromone receptor 39a, isoform C", "protein_names_refseq": "CG31622-PC; Gr39a-PC; gustatory receptor 39D.2; gustatory receptor 39a, isoform C; lethal (2) k05106", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG31622)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "10710312;10731132;11516643;12537572;21416142;22031876", "class_list": "", "function": "Gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates. Plays a role in sustaining courtship behavior in males, possibly through the reception of a stimulating arrestant pheromone., [UniProtKB, PubMed, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008527 taste receptor activity;GO:0015276 ligand-gated monoatomic ion channel activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane;GO:0030424 axon;GO:0030425 dendrite;GO:0043025 neuronal cell body", "go_biological_process": "GO:0008049 male courtship behavior;GO:0007165 signal transduction;GO:0050909 sensory perception of taste;GO:0034220 monoatomic ion transmembrane transport;GO:0007635 chemosensory behavior", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P58957-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P58960-1", "uniprot_id": "GR39B_DROME", "mass": 42334.0, "length": 369, "protein_name": "Putative gustatory receptor 39b", "gene_name": "Gr39b", "organism": "Fruit fly", "refseq_name": "gustatory receptor 39b", "refseq_ac": "NP_724336", "gene_names_uniprotkb": "Gr39b; CG31620; GR39D.1", "gene_names_refseq": "39D.1; 39D1; CG31620; Dmel\\CG31620; GR39D.1; GR39b; Gr39D1; Gr39b", "protein_names_uniprotkb": "Putative gustatory receptor 39b", "protein_names_refseq": "CG31620-PA; Gr39b-PA; gustatory receptor 39D.1; gustatory receptor 39b", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG31620)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "10710312;10731132;11516643;12537572;21870111;22031876", "class_list": "", "function": "Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates (By similarity). Has also atypical sensory function in organ not limited to conventional taste sensing like abdominal ganglions., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0015276 ligand-gated monoatomic ion channel activity;GO:0008527 taste receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane;GO:0030424 axon;GO:0030425 dendrite;GO:0043025 neuronal cell body", "go_biological_process": "GO:0008049 male courtship behavior;GO:0007165 signal transduction;GO:0034220 monoatomic ion transmembrane transport;GO:0007635 chemosensory behavior;GO:0050909 sensory perception of taste", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P58960-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P81641-1", "uniprot_id": "AMYB_DROME", "mass": 53780.0, "length": 494, "protein_name": "Alpha-amylase B", "gene_name": "Amy-d", "organism": "Fruit fly", "refseq_name": "amylase distal", "refseq_ac": "NP_523768", "gene_names_uniprotkb": "Amy-d; AmyB; CG17876", "gene_names_refseq": "AMY; Amy d; Amy(d); Amy-D; Amy-distal; Amy-d; Amy1; Amy3; Amy6; AmyB; AmyD; Amy; CG17876; Dmel\\CG17876; alpha-AMY; alphaAmy; amy-d; amyB(3); amy", "protein_names_uniprotkb": "Alpha-amylase B; 1,4-alpha-D-glucan glucanohydrolase; 3.2.1.1", "protein_names_refseq": "Amy-d-PA; Amylase-B; CG17876-PA; alpha-amylase distal; amylase distal", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG17876); (R-DME-189085)", "pathway_count": 2, "publication_count": 6, "publication_id_list": "10731132;11156987;12537572;1616481;3024105;8536971", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q27578;Q27581;Q27585;Q27882;Q27885;Q27897;Q5BIJ9;Q8WP56;Q95NK4;Q969D1;Q9BH39;Q9BH72;Q9BPS5;Q9BPS6;Q9BPS7;Q9BPS8;Q9BPT0;Q9BPT1;Q9BPT2;Q9BPT3;Q9V7Z0", "ec_number_list": "3.2.1.1", "go_molecular_function": "GO:0005509 calcium ion binding;GO:0004556 alpha-amylase activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0005975 carbohydrate metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P81641-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P82384-1", "uniprot_id": "LCP9_DROME", "mass": 10237.0, "length": 92, "protein_name": "Larval cuticle protein 9", "gene_name": "Lcp9", "organism": "Fruit fly", "refseq_name": "larval cuticle protein 9", "refseq_ac": "NP_523854", "gene_names_uniprotkb": "Lcp9; CG16914", "gene_names_refseq": "CG16914; DmelLcp9; Dmel\\CG16914; LCP9; LCPX; Lcp9; lcp9", "protein_names_uniprotkb": "Larval cuticle protein 9; Larval cuticle protein IX", "protein_names_refseq": "CG16914-PA; Lcp9-PA; larval cuticle protein 9", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG16914)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "10731132;12537572;9654737", "class_list": "", "function": "Component of the cuticle of the larva., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9W109", "ec_number_list": "", "go_molecular_function": "GO:0008010 structural constituent of chitin-based larval cuticle", "go_cellular_component": "GO:0005576 extracellular region;GO:0062129 chitin-based extracellular matrix", "go_biological_process": "GO:0008363 larval chitin-based cuticle development;GO:0040003 chitin-based cuticle development", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "P82384-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P82713-1", "uniprot_id": "CP392_DROME", "mass": 62375.0, "length": 538, "protein_name": "Probable cytochrome P450 309a2", "gene_name": "Cyp309a2", "organism": "Fruit fly", "refseq_name": "cytochrome P450 309a2", "refseq_ac": "NP_608689", "gene_names_uniprotkb": "Cyp309a2; CG18559", "gene_names_refseq": "309a2; CG18559; Cyp309a2; Dmel\\CG18559", "protein_names_uniprotkb": "Probable cytochrome P450 309a2; 1.14.-.-; CYPCCCIXA2", "protein_names_refseq": "CG18559-PA; Cyp309a2-PA; cytochrome P450 309a2", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG18559)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "10731132;12537569;12537572", "class_list": "", "function": "May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q8T422;Q9VQD3", "ec_number_list": "", "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0004497 monooxygenase activity;GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "P82713-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P83100-1", "uniprot_id": "MK14C_DROME", "mass": 41969.0, "length": 356, "protein_name": "Putative mitogen-activated protein kinase 14C", "gene_name": "p38c", "organism": "Fruit fly", "refseq_name": "p38c MAP kinase", "refseq_ac": "NP_996277", "gene_names_uniprotkb": "p38c; CG33338", "gene_names_refseq": "CG33338; Dmel\\CG33338; Dp38c; Mpk2B; P38c; P38; dMPK2B; dp38c; p38MAPK; p38[MAPK]; p38c; p38", "protein_names_uniprotkb": "Putative mitogen-activated protein kinase 14C; 2.7.11.24; MAP kinase 14C; MAP kinase p38c; MAPK 14C", "protein_names_refseq": "CG33338-PA; Mpk2B; p38c MAP kinase; p38c-PA", "tax_id": 7227, "disease": "Parkinson's disease (Disease Ontology:DOID:14330)", "pathway": " (dme:Dmel_CG33338); (R-DME-168638); (R-DME-171007); (R-DME-198753); (R-DME-2559580); (R-DME-4420097); (R-DME-450302); (R-DME-450341); (R-DME-525793); (R-DME-5675221); (R-DME-69601)", "pathway_count": 11, "publication_count": 2, "publication_id_list": "10731132;12537572", "class_list": "", "function": "Kinase involved in a signal transduction pathway., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A8E6X5", "ec_number_list": "2.7.11.17;2.7.11.1;2.7.11.13;2.7.11.24;2.7.11.22;2.7.12.2;2.7.11.21;2.7.10.2;5.6.1.8;2.7.11.11;3.1.3.48;2.7.11.23;3.6.5.2;2.7.12.1;2.7.11.25;2.7.11.12;2.3.2.27;2.7.11.39", "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0004707 MAP kinase activity;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0035556 intracellular signal transduction;GO:0009617 response to bacterium;GO:0010883 regulation of lipid storage;GO:0038066 p38MAPK cascade;GO:1902882 regulation of response to oxidative stress", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "P83100-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P83102-1", "uniprot_id": "DYRK3_DROME", "mass": 92740.0, "length": 828, "protein_name": "Putative dual specificity tyrosine-phosphorylation-regulated kinase 3 homolog", "gene_name": "Dyrk3", "organism": "Fruit fly", "refseq_name": "Dual-specificity tyrosine phosphorylation-regulated kinase 3, isoform A", "refseq_ac": "NP_001033810", "gene_names_uniprotkb": "Dyrk3; CG40478", "gene_names_refseq": "BcDNA:RE60792; CG40478; DDYRK3; DYRK3; Dm3; DmDyrk3; Dmel\\CG40478; Dyrk3; FBtr0100406", "protein_names_uniprotkb": "Putative dual specificity tyrosine-phosphorylation-regulated kinase 3 homolog; 2.7.12.1", "protein_names_refseq": "CG40478-PA; Dual-specificity tyrosine phosphorylation-regulated kinase 3, isoform A; Dyrk3-PA; unknown-telomeric-protein-gene", "tax_id": 7227, "disease": "Down syndrome (Disease Ontology:DOID:14250)", "pathway": " (dme:Dmel_CG40478); (R-DME-6804756)", "pathway_count": 2, "publication_count": 4, "publication_id_list": "10731132;12537569;12537572;18327897", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A4V144;Q2PDL5;Q5LJP2;Q8MT39;Q9Y1N4", "ec_number_list": "2.7.11.17;2.7.11.1;2.7.11.13;2.7.11.24;2.7.10.1;2.7.11.22;2.7.11.21;2.7.10.2;5.6.1.8;2.7.11.11;2.7.11.23;2.7.12.1;2.7.11.25;2.7.11.12;2.7.12.2;2.7.11.39", "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0004713 protein tyrosine kinase activity;GO:0005524 ATP binding;GO:0004712 protein serine/threonine/tyrosine kinase activity;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005856 cytoskeleton", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P83102-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P83292-1", "uniprot_id": "G23A_DROME", "mass": 43587.0, "length": 374, "protein_name": "Gustatory receptor 23a", "gene_name": "Gr23a", "organism": "Fruit fly", "refseq_name": "gustatory receptor 23a, isoform C", "refseq_ac": "NP_523459", "gene_names_uniprotkb": "Gr23a; CG15396; GR23A.1", "gene_names_refseq": "23A.1a; 23A1.b; 23A1a; 23A1b; CG15396; Dmel\\CG15396; GR23A.1; GR23a; Gr23A1a; Gr23A1b; Gr23a.a; Gr23a.b; Gr23aA; Gr23aB; Gr23a", "protein_names_uniprotkb": "Gustatory receptor 23a", "protein_names_refseq": "CG15396-PC; Gr23a-PC; gustatory receptor 23A.1; gustatory receptor 23a, isoform C", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG15396)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "10710312;10731132;11516643;12537572;22031876", "class_list": "", "function": "Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q4V3K4;Q9VQE7", "ec_number_list": "", "go_molecular_function": "GO:0015276 ligand-gated monoatomic ion channel activity;GO:0008527 taste receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane;GO:0030424 axon;GO:0030425 dendrite;GO:0043025 neuronal cell body", "go_biological_process": "GO:0008049 male courtship behavior;GO:0007165 signal transduction;GO:0034220 monoatomic ion transmembrane transport;GO:0007635 chemosensory behavior;GO:0050909 sensory perception of taste", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P83292-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P83295-1", "uniprot_id": "GR64C_DROME", "mass": 48889.0, "length": 419, "protein_name": "Gustatory receptor for sugar taste 64c", "gene_name": "Gr64c", "organism": "Fruit fly", "refseq_name": "gustatory receptor 64c, isoform B", "refseq_ac": "NP_001246610", "gene_names_uniprotkb": "Gr64c; CG32256", "gene_names_refseq": "CG14986; CG32256; Dmel64c; Dmel\\CG32256; GR64c; Gr64c; Gr64; gr64c", "protein_names_uniprotkb": "Gustatory receptor for sugar taste 64c", "protein_names_refseq": "CG32256-PB; Gr64c-PB; gustatory receptor 64c, isoform B", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG32256)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "10731132;11516643;12537572;14608037;17715294;23850280", "class_list": "", "function": "One of the few identified sugar gustatory receptors identified so far and which promotes the starvation-induced increase of feeding motivation., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9VZJ7", "ec_number_list": "", "go_molecular_function": "GO:0015276 ligand-gated monoatomic ion channel activity;GO:0033041 sweet taste receptor activity;GO:0008527 taste receptor activity;GO:0170023 ionotropic sweet taste receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane", "go_biological_process": "GO:0007165 signal transduction;GO:0034220 monoatomic ion transmembrane transport;GO:0050909 sensory perception of taste;GO:0050916 sensory perception of sweet taste", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P83295-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P83296-1", "uniprot_id": "GR64E_DROME", "mass": 52530.0, "length": 451, "protein_name": "Gustatory receptor for sugar taste 64e", "gene_name": "Gr64e", "organism": "Fruit fly", "refseq_name": "gustatory receptor 64e, isoform A", "refseq_ac": "NP_728923", "gene_names_uniprotkb": "Gr64e; CG14988; CG32258; CG33157; DmGr64e; Dmel64e; Dmel\\CG32258; Dmel_CG32258; GR64e; Gr64A2; Gr64; gr64e", "gene_names_refseq": "CG14988; CG32258; CG33157; DmGr64e; Dmel64e; Dmel\\CG32258; GR64e; Gr64A2; Gr64e; Gr64; gr64e", "protein_names_uniprotkb": "Gustatory receptor for sugar taste 64e", "protein_names_refseq": "CG32258-PA; Gr64e-PA; gustatory receptor 64A2; gustatory receptor 64e, isoform A", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG32258)", "pathway_count": 1, "publication_count": 17, "publication_id_list": "10731132;11516643;12537568;12537569;12537572;12537573;12537574;14608037;16110336;17569856;17569867;17715294;22057190;23850280;25589440;26109356;26109357", "class_list": "", "function": "One of the few identified sugar gustatory receptors identified so far and which promotes the starvation-induced increase of feeding motivation. confers responsiveness to glycerol and is required for feeding preference for beer and other sources that have fermenting yeast., [UniProtKB, PubMed, PubMed, PubMed]; Plays a role in the sugar gustatory response., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q8IRC5;Q9VZJ5", "ec_number_list": "", "go_molecular_function": "GO:0015276 ligand-gated monoatomic ion channel activity;GO:0033041 sweet taste receptor activity;GO:0170023 ionotropic sweet taste receptor activity;GO:0008527 taste receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007165 signal transduction;GO:0034220 monoatomic ion transmembrane transport;GO:0050916 sensory perception of sweet taste", "synthesized_glycan_count": 0, "hit_score": 1.8, "record_id": "P83296-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P83869-1", "uniprot_id": "DSO2_DROME", "mass": 4995.0, "length": 46, "protein_name": "Daisho2", "gene_name": "Dso2", "organism": "Fruit fly", "refseq_name": "Daisho2", "refseq_ac": "NP_001033962", "gene_names_uniprotkb": "Dso2; CG33990; IM14", "gene_names_refseq": "CG33990; DIM 14; DIM14; Dmel\\CG33990; Dso2; IM14; dso2; im14", "protein_names_uniprotkb": "Daisho2; DIM-14; DIM4; Immune-induced peptide 14", "protein_names_refseq": "CG33990-PA; Daisho2; Dso2-PA; immune induced molecule 14", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG33990)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "10731132;12537572;14645501;32038657;9736738", "class_list": "", "function": "Peptide which plays a role in the humoral immune response to a subset of filamentous fungi, including F.oxysporum and F.verticillioides., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D1Z361;Q2PE21", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0019731 antibacterial humoral response;GO:0019732 antifungal humoral response;GO:0045087 innate immune response;GO:0009617 response to bacterium", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P83869-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P84029-1", "uniprot_id": "CYC2_DROME", "mass": 11735.0, "length": 108, "protein_name": "Cytochrome c-2", "gene_name": "Cyt-c-p", "organism": "Fruit fly", "refseq_name": "cytochrome c proximal, isoform B", "refseq_ac": "NP_001285984", "gene_names_uniprotkb": "Cyt-c-p; CG17903; CYC2; CYC; CYTC2; Cyct-c-p; Cyt C; Cyt c; Cyt-c-P; Cyt-c2; Cyt-c; CytC-2; CytC; Cytc-p; Cytc; DC4; DMc01; Dmel\\CG17903; Dmel_CG17903; P84029; cyt c-p; cyt c; cyt-c-p; cyt-c2; cyt.c; cytC-p; cytochrome c; dCyt.C-p; dc4; l(2)k13905; pDMc01", "gene_names_refseq": "CG17903; CYC2; CYC; Cyct-c-p; Cyt C; Cyt c; Cyt-c-P; Cyt-c-p; Cyt-c2; Cyt-c; CytC-2; CytC; Cytc-p; Cytc; DC4; DMc01; Dmel\\CG17903; P84029; cyt c-p; cyt c; cyt-c-p; cyt-c2; cyt.c; cytC-p; cytochrome c; dCyt.C-p; dc4; l(2)k13905; pDMc01", "protein_names_uniprotkb": "Cytochrome c-2; Cytochrome c-proximal", "protein_names_refseq": "CG17903-PB; Cyt-c-p-PB; Cytochrome-c-proximal; cytochrome c DC4; cytochrome c proximal, isoform B; cytochrome c proximal; cytochrome c; cytochrome-c-p; lethal (2) k13905", "tax_id": 7227, "disease": "Huntington's disease (Disease Ontology:DOID:12858); thrombocytopenia (Disease Ontology:DOID:1588); pancreatic cancer (Disease Ontology:DOID:1793); lung squamous cell carcinoma (Disease Ontology:DOID:3907); lung non-small cell carcinoma (Disease Ontology:DOID:3908); hyperglycemia (Disease Ontology:DOID:4195); cholangiocarcinoma (Disease Ontology:DOID:4947)", "pathway": " (dme:Dmel_CG17903); (R-DME-111457); (R-DME-111458); (R-DME-111459); (R-DME-111461); (R-DME-3299685); (R-DME-5620971); (R-DME-5628897); (R-DME-611105); (R-DME-9627069); (R-DME-9707564)", "pathway_count": 11, "publication_count": 14, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357;2984675;2987802;3029051", "class_list": "", "function": "Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 7, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "P00033;P00034;Q9VJJ3", "ec_number_list": "", "go_molecular_function": "GO:0009055 electron transfer activity;GO:0046872 metal ion binding;GO:0020037 heme binding", "go_cellular_component": "GO:0005758 mitochondrial intermembrane space;GO:0005739 mitochondrion;GO:0005829 cytosol", "go_biological_process": "GO:0006123 mitochondrial electron transport, cytochrome c to oxygen;GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c;GO:0006119 oxidative phosphorylation;GO:0022904 respiratory electron transport chain", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "P84029-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P84345-1", "uniprot_id": "ATP8_DROME", "mass": 6365.0, "length": 53, "protein_name": "ATP synthase protein 8", "gene_name": "mt:ATPase8", "organism": "Fruit fly", "refseq_name": "ATP synthase F0 subunit 8", "refseq_ac": "YP_009047269", "gene_names_uniprotkb": "mt:ATPase8; ATP8; ATPase8; Mtatp8", "gene_names_refseq": "ATP8; mt:ATPase8", "protein_names_uniprotkb": "ATP synthase protein 8; A6L; F-ATPase subunit 8", "protein_names_refseq": "ATP synthase F0 subunit 8", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG34072)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "10903372;11298822;18296276;18727704;6408489;8825764", "class_list": "", "function": "Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "B2L9S1;B6E0P5;P03932", "ec_number_list": "", "go_molecular_function": "GO:0015078 proton transmembrane transporter activity", "go_cellular_component": "GO:0005743 mitochondrial inner membrane;GO:0045259 proton-transporting ATP synthase complex", "go_biological_process": "GO:0015986 proton motive force-driven ATP synthesis;GO:0042776 proton motive force-driven mitochondrial ATP synthesis", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P84345-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P91615-1", "uniprot_id": "ADHR_DROME", "mass": 30274.0, "length": 272, "protein_name": "Alcohol dehydrogenase-related 31 kDa protein", "gene_name": "Adhr", "organism": "Fruit fly", "refseq_name": "Adh-related, isoform B", "refseq_ac": "NP_001027272", "gene_names_uniprotkb": "Adhr; 3'ORF; ADHR; ADH[r]; Adh-dup; Adh[r]; BG:DS01486.9; CG32954; CG3484; Dmel\\CG3484; Dmel_CG3484", "gene_names_refseq": "3'ORF; ADHR; ADH[r]; Adh-dup; Adh[r]; Adhr; BG:DS01486.9; CG32954; CG3484; Dmel\\CG3484", "protein_names_uniprotkb": "Alcohol dehydrogenase-related 31 kDa protein", "protein_names_refseq": "Adh related; Adh-related, isoform B; Adhr-PB; CG3484-PB; alcohol dehydrogenase related; alcohol dehydrogenase-related", "tax_id": 7227, "disease": "inflammatory bowel disease (Disease Ontology:DOID:0050589); primary hypertrophic osteoarthropathy (Disease Ontology:DOID:14283); colon carcinoma (Disease Ontology:DOID:1520); carcinoma (Disease Ontology:DOID:305); prolactinoma (Disease Ontology:DOID:5394); growth hormone secreting pituitary adenoma (Disease Ontology:DOID:6255); pulmonary hypertension (Disease Ontology:DOID:6432); peptic ulcer disease (Disease Ontology:DOID:750)", "pathway": " (dme:Dmel_CG3484); (R-DME-2142700); (R-DME-9018676); (R-DME-9018896)", "pathway_count": 4, "publication_count": 14, "publication_id_list": "10471707;10731132;12537568;12537572;12537573;12537574;16110336;1673107;17569856;17569867;25589440;26109356;26109357;9155028", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 8, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A4V0Q4;Q24230;Q6LAE8;Q9NKB9;Q9VJS2", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "P91615-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P91926-1", "uniprot_id": "AP2A_DROME", "mass": 105620.0, "length": 940, "protein_name": "AP-2 complex subunit alpha", "gene_name": "AP-2alpha", "organism": "Fruit fly", "refseq_name": "adaptor protein complex 2, alpha subunit, isoform A", "refseq_ac": "NP_476819", "gene_names_uniprotkb": "AP-2alpha; CG4260", "gene_names_refseq": "AP-2alpha; AP-2; AP2alpha; AP2; Ada; Alpha-Adaptin; Ap-2alpha; CG31654; CG4260; D-Ada; D-alphaAda; Dmel\\CG4260; MENE (2L)-A; MENE(2L)-A; ada; alpha-Adaptin; alpha-Ada; alpha-adaptin; alpha-ada; alphaAda; alphaada; alpha; apl3; cg4260; dAP-2a; l(2)06694; l(2)SH0460; l(2)SH2 0460", "protein_names_uniprotkb": "AP-2 complex subunit alpha; Alpha-adaptin", "protein_names_refseq": "AP-2alpha-PA; Alpha-adaptin; CG4260-PA; adaptor protein complex 2, alpha subunit, isoform A; alpha adaptin; alphaAdaptin; clathrin AP-2 complex; lethal (2) SH0460", "tax_id": 7227, "disease": "autism spectrum disorder (Disease Ontology:DOID:0060041)", "pathway": " (dme:Dmel_CG4260); (R-DME-177504); (R-DME-3928665); (R-DME-416993); (R-DME-437239); (R-DME-5099900); (R-DME-5140745); (R-DME-6798695); (R-DME-8856825); (R-DME-8856828); (R-DME-8866427); (R-DME-8964038)", "pathway_count": 12, "publication_count": 6, "publication_id_list": "10731132;12537572;17018572;18327897;9118220;9285813", "class_list": "", "function": "Adaptins are components of the adapter complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. AP-2alpha is a subunit of the plasma membrane adapter., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "B3DN51;O01937;Q7KTZ5;Q86P64;Q9VPP4", "ec_number_list": "", "go_molecular_function": "GO:0035615 clathrin adaptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005905 clathrin-coated pit;GO:0030122 AP-2 adaptor complex;GO:0098793 presynapse", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0006897 endocytosis;GO:0015031 protein transport;GO:0030100 regulation of endocytosis;GO:0031623 receptor internalization", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P91926-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P91931-1", "uniprot_id": "DCAM_DROME", "mass": 39768.0, "length": 347, "protein_name": "S-adenosylmethionine decarboxylase proenzyme", "gene_name": "SamDC", "organism": "Fruit fly", "refseq_name": "S-adenosylmethionine decarboxylase", "refseq_ac": "NP_477223", "gene_names_uniprotkb": "SamDC; CG5029", "gene_names_refseq": "CG5029; Dmel\\CG5029; SamDC; l(2)31Dc; l(2)31Dd; l(2)31De; samdc", "protein_names_uniprotkb": "S-adenosylmethionine decarboxylase proenzyme; 4.1.1.50; AdoMetDC; SAMDC", "protein_names_refseq": "CG5029-PA; S-adenosyl decarboxylase; S-adenosylmethionine decarboxylase; SamDC-PA", "tax_id": 7227, "disease": "prostate cancer (Disease Ontology:DOID:10283); lung non-small cell carcinoma (Disease Ontology:DOID:3908)", "pathway": " (dme:Dmel_CG5029); (R-DME-351202)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "10731132;12537572;9435790", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "P91925;Q58CK1;Q9VKY9", "ec_number_list": "4.1.1.50", "go_molecular_function": "GO:0004014 adenosylmethionine decarboxylase activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0050829 defense response to Gram-negative bacterium;GO:0006597 spermine biosynthetic process;GO:0008295 spermidine biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "P91931-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q01068-1", "uniprot_id": "ESM3_DROME", "mass": 24983.0, "length": 224, "protein_name": "Enhancer of split m3 protein", "gene_name": "E(spl)m3-HLH", "organism": "Fruit fly", "refseq_name": "enhancer of split m3, helix-loop-helix", "refseq_ac": "NP_524509", "gene_names_uniprotkb": "E(spl)m3-HLH; CG8346; HLHm3", "gene_names_refseq": "CG8346; Dmel\\CG8346; E(Spl)-HLH-m3; E(spl)-C; E(spl)-m3; E(spl)C m3; E(spl)C; E(spl)M3; E(spl)m3-HLH; E(spl)m3; HLH-m3; HLHM3; HLHm3; bHLHc14; m3", "protein_names_uniprotkb": "Enhancer of split m3 protein; E(spl)m3; HLH-m3", "protein_names_refseq": "CG8346-PA; E(spl) region transcript m3; E(spl)m3-HLH-PA; enhancer of split m3, helix-loop-helix; enhancer of split m3; split locus enhancer protein m3", "tax_id": 7227, "disease": "oral squamous cell carcinoma (Disease Ontology:DOID:0050866); coronary artery disease (Disease Ontology:DOID:3393); lung adenocarcinoma (Disease Ontology:DOID:3910); esophageal cancer (Disease Ontology:DOID:5041)", "pathway": " (dme:Dmel_CG8346)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "10731132;12537569;12537572;1427040;1528887;15537803;8001118", "class_list": "", "function": "Transcriptional repressor of genes that require a bHLH protein for their transcription. May serve as a transcriptional regulator of the Achaete-scute complex (AS-C) genes. Belongs to notch signaling pathway and depends on Su(H) for transcriptional activation., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q5S455;Q5S479;Q5S4J9", "ec_number_list": "", "go_molecular_function": "GO:0046983 protein dimerization activity;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0043565 sequence-specific DNA binding;GO:1990837 sequence-specific double-stranded DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0007219 Notch signaling pathway;GO:0007399 nervous system development;GO:0030154 cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q01068-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q01583-4", "uniprot_id": "DGK1_DROME", "mass": 132960.0, "length": 1211, "protein_name": "Diacylglycerol kinase 1", "gene_name": "Dgk", "organism": "Fruit fly", "refseq_name": "diacyl glycerol kinase, isoform E", "refseq_ac": "NP_001097219", "gene_names_uniprotkb": "Dgk; CG34361; DGK1", "gene_names_refseq": "CG12820; CG1535; CG18654; CG34361; DAGK; DGKb; DGK; Dgk; Dmel\\CG34361; dDGK; dgk", "protein_names_uniprotkb": "Diacylglycerol kinase 1; 2.7.1.107; DAG kinase 1; DGK 1; Diglyceride kinase 1", "protein_names_refseq": "CG34361-PE; Dgk-PE; diacyl glycerol kinase, isoform E; diacylglycerol kinase", "tax_id": 7227, "disease": "glucose metabolism disease (Disease Ontology:DOID:4194)", "pathway": " (dme:Dmel_CG34361); (R-DME-114508)", "pathway_count": 2, "publication_count": 4, "publication_id_list": "10731132;12537572;1321433;8380995", "class_list": "", "function": "Upon cell stimulation converts the second messenger diacylglycerol into phosphatidate, initiating the resynthesis of phosphatidylinositols and attenuating protein kinase C activity (By similarity). May have a role in the development of the embryonic nervous system and the function of the adult nervous system and muscle; regulating signal transduction in neurons., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 4, "predicted_n_glycosites": 0, "predicted_o_glycosites": 4, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "A8DY60;A8DY61;Q53YF9;Q7KQR7;Q8MKP0;Q9V327", "ec_number_list": "2.7.1.107;2.7.1.94;2.7.1.138", "go_molecular_function": "GO:0004143 ATP-dependent diacylglycerol kinase activity;GO:0005524 ATP binding;GO:0008270 zinc ion binding;GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0046339 diacylglycerol metabolic process;GO:0006654 phosphatidic acid biosynthetic process;GO:0035556 intracellular signal transduction;GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q01583-4", "record_type": "protein" }, { "uniprot_canonical_ac": "Q01617-4", "uniprot_id": "CPO_DROME", "mass": 63296.0, "length": 606, "protein_name": "Protein couch potato", "gene_name": "cpo", "organism": "Fruit fly", "refseq_name": "couch potato, isoform T", "refseq_ac": "NP_001014631", "gene_names_uniprotkb": "cpo; CG43738", "gene_names_refseq": "1824; 3603; 5339; 6015; BcDNA:AT31405; CG12349; CG18434; CG18435; CG31243; CG42457; CG43738; CPO; Cpo; Dmel\\CG43738; E(sda)N; Line N; ORE-17; cg18435; cpo; l(3)01432; l(3)6015; l(3)j4A1; l(3)j4D4; l(3)j7E2; l(3)j9B3; l(3)rJ553; l(3)s2336", "protein_names_uniprotkb": "Protein couch potato", "protein_names_refseq": "CG43738-PT; couch potato, isoform T; couch potato; couchpotato; cpo-PT", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG43738)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "10731132;12537569;12537572;1427076;18852464", "class_list": "", "function": "May play a role in the development or function of the peripheral nervous system by regulating the processing of nervous system-specific transcripts., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A4V319;E1JIN7;Q59DW5;Q59DW6;Q8IGV9;Q8MQI9;Q9VED9;Q9VEE1", "ec_number_list": "", "go_molecular_function": "GO:0003729 mRNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0045202 synapse", "go_biological_process": "GO:0007268 chemical synaptic transmission;GO:0022611 dormancy process;GO:0035206 regulation of hemocyte proliferation", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q01617-4", "record_type": "protein" }, { "uniprot_canonical_ac": "Q01819-1", "uniprot_id": "CONN_DROME", "mass": 77161.0, "length": 691, "protein_name": "Connectin", "gene_name": "Con", "organism": "Fruit fly", "refseq_name": "connectin, isoform B", "refseq_ac": "NP_001246635", "gene_names_uniprotkb": "Con; CG7503", "gene_names_refseq": "CG7503; CON; CT1840; Con; Dmel\\CG7503; Ubx-t35; anon-64C; conn; con", "protein_names_uniprotkb": "Connectin", "protein_names_refseq": "CG7503-PB; Con-PB; connectin, isoform B; connectin; transcript-35", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG7503)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "10731132;12537569;12537572;1363542;1505024", "class_list": "", "function": "Cell adhesion protein involved in target recognition during neuromuscular development. Mediates homophilic cellular adhesion., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q6AWM0;Q8MRN1;Q9VZ74", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane;GO:0009986 cell surface;GO:0031594 neuromuscular junction;GO:0044295 axonal growth cone;GO:0098552 side of membrane", "go_biological_process": "GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007413 axonal fasciculation;GO:0016200 synaptic target attraction", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q01819-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q02308-1", "uniprot_id": "HLES_DROME", "mass": 111100.0, "length": 1077, "protein_name": "Protein hairless", "gene_name": "H", "organism": "Fruit fly", "refseq_name": "hairless, isoform C", "refseq_ac": "NP_524418", "gene_names_uniprotkb": "H; CG5460", "gene_names_refseq": "CG5460; Dmel\\CG5460; H", "protein_names_uniprotkb": "Protein hairless", "protein_names_refseq": "CG5460-PC; H-PC; hairless, isoform C; hairless", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG5460)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "10731132;12537569;12537572;1419850;1516831;18327897", "class_list": "", "function": "Is a potent antagonist of neurogenic gene activity during sensory organ development. The expression of distinct cell fates by the trichogen (shaft) / tormogen (socket) sister cell pair depends on the level of H activity. A certain threshold level of H activity is required, below which both sister cells adopt the tormogen fate., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A4V358;A4V359;Q6AWM8;Q960W5;Q9VDK0;Q9VDK1", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0003714 transcription corepressor activity", "go_cellular_component": "GO:0090571 RNA polymerase II transcription repressor complex", "go_biological_process": "GO:0008052 sensory organ boundary specification;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0035019 somatic stem cell population maintenance;GO:0045746 negative regulation of Notch signaling pathway;GO:0036335 intestinal stem cell homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q02308-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q02910-1", "uniprot_id": "CPN_DROME", "mass": 84596.0, "length": 864, "protein_name": "Calphotin", "gene_name": "Cpn", "organism": "Fruit fly", "refseq_name": "calphotin, isoform A", "refseq_ac": "NP_731673", "gene_names_uniprotkb": "Cpn; CG4795; cap", "gene_names_refseq": "77H5; Ag 72H5; Ag72H5; CG4795; Cpn; Dmel\\CG4795; Mab77H5; cap; cpn", "protein_names_uniprotkb": "Calphotin", "protein_names_refseq": "CG4795-PA; Cpn-PA; calcium-binding protein; calphotin, isoform A; calphotin; monoclonal antibody 77H5", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG4795)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "10731132;12537569;12537572;17018572;8094559;8434015", "class_list": "", "function": "Plays important roles in both rhabdomere development and in photoreceptor cell survival. Might function as a calcium-sequestering 'sponge' to regulate the amount of free cytoplasmic calcium. It binds 0.3 mole of Ca(2+) per mole of protein., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 7, "predicted_n_glycosites": 0, "predicted_o_glycosites": 7, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 7, "binding_glycan_count": 0, "secondary_ac_list": "B5X510;Q95U45;Q9VGC8;Q9VGC9", "ec_number_list": "", "go_molecular_function": "GO:0140314 calcium ion sequestering activity", "go_cellular_component": "GO:0005829 cytosol;GO:0030424 axon;GO:0044297 cell body", "go_biological_process": "GO:0006874 intracellular calcium ion homeostasis;GO:0007601 visual perception", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q02910-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q02936-1", "uniprot_id": "HH_DROME", "mass": 52150.0, "length": 471, "protein_name": "Protein hedgehog", "gene_name": "hh", "organism": "Fruit fly", "refseq_name": "hedgehog", "refseq_ac": "NP_001034065", "gene_names_uniprotkb": "hh; CG4637", "gene_names_refseq": "CG4637; Dmel\\CG4637; Dmhh; HH; Hg; Hh; Mir; Mrt; anon-WO0134654.19; anon-WO0182946.19; bar-3; bar3; bar; hg; hh; l(3)hh; l(3)neo56; l(3)neo57", "protein_names_uniprotkb": "Protein hedgehog; 3.1.-.-", "protein_names_refseq": "CG4637-PB; PKC; atypical; bar-on-3; hedgehog; hedghog; hh-PB; mirabile; moonrat", "tax_id": 7227, "disease": "primary bacterial infectious disease (Disease Ontology:DOID:0050338); familial adenomatous polyposis (Disease Ontology:DOID:0050424); acrocapitofemoral dysplasia (Disease Ontology:DOID:0050604); primary progressive multiple sclerosis (Disease Ontology:DOID:0050784); 46,XY gonadal dysgenesis with minifascicular neuropathy (Disease Ontology:DOID:0051055); autism spectrum disorder (Disease Ontology:DOID:0060041); pre-malignant neoplasm (Disease Ontology:DOID:0060071); annular pancreas (Disease Ontology:DOID:0060850); preaxial polydactyly II (Disease Ontology:DOID:0060986); esophageal atresia/tracheoesophageal fistula (Disease Ontology:DOID:0080171); Parkinsonism (Disease Ontology:DOID:0080855); holoprosencephaly 3 (Disease Ontology:DOID:0110875); brachydactyly type A1 (Disease Ontology:DOID:0110964); solitary median maxillary central incisor (Disease Ontology:DOID:0111380); hypoplastic or aplastic tibia with polydactyly (Disease Ontology:DOID:0111564); 46,XY sex reversal 7 (Disease Ontology:DOID:0111774); syndactyly type 1 (Disease Ontology:DOID:0111816); syndactyly type 4 (Disease Ontology:DOID:0111818); Hirschsprung's disease (Disease Ontology:DOID:10487); stomach cancer (Disease Ontology:DOID:10534); membranous glomerulonephritis (Disease Ontology:DOID:10976); polydactyly (Disease Ontology:DOID:1148); retinopathy of prematurity (Disease Ontology:DOID:13025); focal segmental glomerulosclerosis (Disease Ontology:DOID:1312); biliary atresia (Disease Ontology:DOID:13608); 46,XY complete gonadal dysgenesis (Disease Ontology:DOID:14448); hypothyroidism (Disease Ontology:DOID:1459); VACTERL association (Disease Ontology:DOID:14679); transient cerebral ischemia (Disease Ontology:DOID:224); multiple sclerosis (Disease Ontology:DOID:2377); nevoid basal cell carcinoma syndrome (Disease Ontology:DOID:2512); basal cell carcinoma (Disease Ontology:DOID:2513); IgA glomerulonephritis (Disease Ontology:DOID:2986); temporal lobe epilepsy (Disease Ontology:DOID:3328); middle cerebral artery infarction (Disease Ontology:DOID:3525); holoprosencephaly (Disease Ontology:DOID:4621); myocardial infarction (Disease Ontology:DOID:5844); chronic kidney disease (Disease Ontology:DOID:784); osteoarthritis (Disease Ontology:DOID:8398); gastrointestinal stromal tumor (Disease Ontology:DOID:9253); colorectal cancer (Disease Ontology:DOID:9256); ocular hypertension (Disease Ontology:DOID:9282)", "pathway": " (dme:Dmel_CG4637); (R-DME-209214); (R-DME-209338); (R-DME-209471); (R-DME-5358346); (R-DME-5362798); (R-DME-5632681)", "pathway_count": 7, "publication_count": 41, "publication_id_list": "10549295;10619433;10731132;11319862;11395778;11486055;11861468;12537572;12586063;12663920;12783860;1280560;1340474;1394430;14523402;14597665;14614827;14636583;14729575;15189162;15300262;15563523;15592457;15598741;15616566;15691765;15875013;16041759;16630821;17077139;17182028;18198278;25639794;27195754;7885476;8166882;8824192;8898207;8906787;8906794;9335337", "class_list": "", "function": "The C-terminal part of the hedgehog protein precursor displays an autoproteolysis activity that results in the cleavage of the full-length protein into two parts (N-product and C-product) (PubMed:7885476). In addition, the C-terminal part displays a cholesterol transferase activity that results by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated N-product (By similarity). Once cleaved, the C-product has no signaling activity and diffuses from the cell (PubMed:12586063)., [UniProtKB, PubMed, UniProtKB, PubMed]; The dually lipidated hedgehog protein N-product is a morphogen which is essential for a variety of patterning events during development (PubMed:11319862, PubMed:1340474, PubMed:1394430, PubMed:25639794, PubMed:27195754, PubMed:8166882). Establishes the anterior-posterior axis of the embryonic segments and patterns the larval imaginal disks. Binds to the patched (ptc) receptor, which functions in association with smoothened (smo), to activate the transcription of target genes wingless (wg), decapentaplegic (dpp) and ptc. In the absence of hh, ptc represses the constitutive signaling activity of smo through fused (fu). Essential component of a signaling pathway which regulates the Duox-dependent gut immune response to bacterial uracil; required to activate Cad99C-dependent endosome formation, norpA-dependent Ca2+ mobilization and p38 MAPK, which are essential steps in the Duox-dependent production of reactive oxygen species (ROS) in response to intestinal bacterial infection (PubMed:25639794). During photoreceptor differentiation, it up-regulates transcription of Ubr3, which in turn promotes the hh-signaling pathway by mediating the ubiquitination and degradation of cos (PubMed:11319862, PubMed:1340474, PubMed:1394430, PubMed:25639794, PubMed:27195754, PubMed:8166882)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 4, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 42, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A4V396;Q9VCQ4", "ec_number_list": "5.3.4.1;3.1.-.-;3.6.4.6;2.3.2.27;3.4.19.-;5.6.1.5;3.1.1.98;2.3.1.-", "go_molecular_function": "GO:0005509 calcium ion binding;GO:0008233 peptidase activity;GO:0016015 morphogen activity;GO:0005113 patched binding;GO:0140853 cholesterol-protein transferase activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0005615 extracellular space;GO:0005634 nucleus;GO:0005768 endosome;GO:0005829 cytosol", "go_biological_process": "GO:0001708 cell fate specification;GO:0007418 ventral midline development;GO:0007442 hindgut morphogenesis;GO:0007267 cell-cell signaling;GO:0007507 heart development", "synthesized_glycan_count": 0, "hit_score": 4.2, "record_id": "Q02936-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q03445-1", "uniprot_id": "GLR1_DROME", "mass": 111668.0, "length": 991, "protein_name": "Glutamate receptor 1", "gene_name": "GluRIA", "organism": "Fruit fly", "refseq_name": "glutamate receptor IA", "refseq_ac": "NP_476855", "gene_names_uniprotkb": "GluRIA; CG8442; Glu-RI", "gene_names_refseq": "CG8442; DGluR-IA; DGluR-I; DGluRI; DmelGlu-R1; Dmel\\CG8442; Dro GluRIA; Glu-R1; Glu-RI; GluR1A; GluR1; GluRIA; GluRIIA; GluRI; dGluRI; dglur-IA", "protein_names_uniprotkb": "Glutamate receptor 1; Glutamate receptor I; Kainate-selective glutamate receptor; dGLUR-I", "protein_names_refseq": "CG8442-PA; GluRIA-PA; glutamate receptor IA; glutamate receptor I; glutamate receptor kainate-selective subunit; glutamate receptor subunit; kainate receptor", "tax_id": 7227, "disease": "withdrawal disorder (Disease Ontology:DOID:0060001); syndromic X-linked intellectual disability 94 (Disease Ontology:DOID:0060823); autosomal dominant intellectual developmental disorder 67 (Disease Ontology:DOID:0061040); autosomal recessive intellectual developmental disorder 76 (Disease Ontology:DOID:0081235); traumatic brain injury (Disease Ontology:DOID:0081292); neurodegenerative disease (Disease Ontology:DOID:1289); hepatic encephalopathy (Disease Ontology:DOID:13413); alcohol use disorder (Disease Ontology:DOID:1574); depressive disorder (Disease Ontology:DOID:1596); status epilepticus (Disease Ontology:DOID:1824); epilepsy (Disease Ontology:DOID:1826); morphine dependence (Disease Ontology:DOID:2560); central nervous system disease (Disease Ontology:DOID:331); schizoaffective disorder (Disease Ontology:DOID:5418); schizophrenia (Disease Ontology:DOID:5419); amphetamine abuse (Disease Ontology:DOID:670); cocaine abuse (Disease Ontology:DOID:809); hyperhomocysteinemia (Disease Ontology:DOID:9279); cannabis abuse (Disease Ontology:DOID:9505); cocaine dependence (Disease Ontology:DOID:9975); heroin dependence (Disease Ontology:DOID:9976)", "pathway": " (dme:Dmel_CG8442); (R-DME-399710); (R-DME-416993); (R-DME-438066); (R-DME-8849932)", "pathway_count": 5, "publication_count": 3, "publication_id_list": "10731132;12537572;1359540", "class_list": "", "function": "Receptor for glutamate. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists (By similarity). Forms ligand-gated ion channels which are activated by kainate., [UniProtKB, PubMed]", "predicted_glycosites": 9, "predicted_n_glycosites": 9, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 21, "glyco_site_count": 9, "binding_glycan_count": 0, "secondary_ac_list": "B6IDJ5;Q86PC2;Q9VRX9", "ec_number_list": "", "go_molecular_function": "GO:0015277 kainate selective glutamate receptor activity;GO:1904315 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential;GO:0008066 glutamate receptor activity", "go_cellular_component": "GO:0008328 ionotropic glutamate receptor complex;GO:0005886 plasma membrane;GO:0098839 postsynaptic density membrane", "go_biological_process": "GO:0035249 synaptic transmission, glutamatergic;GO:0006812 monoatomic cation transport;GO:0050804 modulation of chemical synaptic transmission", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q03445-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q04787-1", "uniprot_id": "BSH_DROME", "mass": 45714.0, "length": 429, "protein_name": "Brain-specific homeobox protein", "gene_name": "bsh", "organism": "Fruit fly", "refseq_name": "brain-specific homeobox, isoform C", "refseq_ac": "NP_477350", "gene_names_uniprotkb": "bsh; CG10604", "gene_names_refseq": "BSH; Bsh; CG10604; Dmel\\CG10604; E86; Hox11-310; bsh; bsk; lambdaE86", "protein_names_uniprotkb": "Brain-specific homeobox protein", "protein_names_refseq": "Brain-specific homeobox; CG10604-PC; brain specific homeobox; brain-specific homeobox, isoform C; bsh-PC", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG10604); (R-DME-8853884)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "10731132;12537572;8101170", "class_list": "", "function": "DNA binding protein that function as transcriptional activator (By similarity). May play a role in the determination and function of cell types in the brain., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q4V6V3;Q7KT32;Q9VIS2", "ec_number_list": "", "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0030154 cell differentiation;GO:0006355 regulation of DNA-templated transcription;GO:0007420 brain development", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q04787-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q05337-1", "uniprot_id": "GNAF_DROME", "mass": 46207.0, "length": 399, "protein_name": "Guanine nucleotide-binding protein G(f) subunit alpha", "gene_name": "Galphaf", "organism": "Fruit fly", "refseq_name": "G protein alpha subunit f", "refseq_ac": "NP_524118", "gene_names_uniprotkb": "Galphaf; CG12232; G-A73B; Galpha73B", "gene_names_refseq": "CG12232; Dmel\\CG12232; GNAS/L; G[[f]]; Galpha73B; Galpha73b; Galpha[[f]]73B; Galphaf; Gfalpha; Gf", "protein_names_uniprotkb": "Guanine nucleotide-binding protein G(f) subunit alpha; G protein alpha f subunit", "protein_names_refseq": "CG12232-PA; G protein alpha 73B; G protein alpha f subunit; G protein alpha subunit f; GTP-binding protein alpha-subunit; Galphaf-PA; Gf alpha", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG12232)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "10731132;12537572;7683429", "class_list": "", "function": "Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "C0P8M4;Q9VV88", "ec_number_list": "", "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0046872 metal ion binding;GO:0001664 G protein-coupled receptor binding;GO:0031683 G-protein beta/gamma-subunit complex binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005834 heterotrimeric G-protein complex", "go_biological_process": "GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway;GO:0051489 regulation of filopodium assembly;GO:0007498 mesoderm development;GO:0007606 sensory perception of chemical stimulus;GO:0035208 positive regulation of hemocyte proliferation", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q05337-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q06453-1", "uniprot_id": "AL_DROME", "mass": 43657.0, "length": 408, "protein_name": "Homeobox protein aristaless", "gene_name": "al", "organism": "Fruit fly", "refseq_name": "aristaless", "refseq_ac": "NP_722629", "gene_names_uniprotkb": "al; CG3935", "gene_names_refseq": "A1; AL; Al; CG3935; Dmel\\CG3935; L13-4; al; lambda13-4", "protein_names_uniprotkb": "Homeobox protein aristaless", "protein_names_refseq": "CG3935-PA; al-PA; aristaless", "tax_id": 7227, "disease": "lissencephaly (Disease Ontology:DOID:0050453); early infantile epileptic encephalopathy (Disease Ontology:DOID:0050709); non-syndromic X-linked intellectual disability (Disease Ontology:DOID:0050776); syndromic X-linked intellectual disability (Disease Ontology:DOID:0060309); syndromic X-linked intellectual disability Hedera type (Disease Ontology:DOID:0060806); developmental and epileptic encephalopathy 1 (Disease Ontology:DOID:0080468); non-syndromic X-linked intellectual disability ARX-related (Disease Ontology:DOID:0112021); non-syndromic X-linked intellectual disability 1 (Disease Ontology:DOID:0112038); corpus callosum agenesis-abnormal genitalia syndrome (Disease Ontology:DOID:0112151); X-linked lissencephaly 2 (Disease Ontology:DOID:0112238); Partington syndrome (Disease Ontology:DOID:14744); epilepsy (Disease Ontology:DOID:1826); type 2 diabetes mellitus (Disease Ontology:DOID:9352)", "pathway": " (dme:Dmel_CG3935)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "10731132;12537569;12537572;8093690", "class_list": "", "function": "Involved in the morphogenesis of proximal and distal pattern elements in a subset of appendages. Also has a role in early imaginal disk development., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 13, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9VPP1", "ec_number_list": "", "go_molecular_function": "GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0032991 protein-containing complex", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0045892 negative regulation of DNA-templated transcription;GO:0048666 neuron development;GO:0007480 imaginal disc-derived leg morphogenesis;GO:0022416 chaeta development", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q06453-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q07093-1", "uniprot_id": "GCYH_DROME", "mass": 75663.0, "length": 676, "protein_name": "Head-specific guanylate cyclase", "gene_name": "Gycalpha99B", "organism": "Fruit fly", "refseq_name": "guanylyl cyclase alpha-subunit at 99B", "refseq_ac": "NP_477088", "gene_names_uniprotkb": "Gycalpha99B; CG1912; GYC-ALPHA-63A; GYC; Gyc99B; dgc1", "gene_names_refseq": "CG1912; Dgc1; Dgcalpha1; Dmel\\CG1912; GCalpha1; GYCa 99B; Gcalpha1; Gycalpha-99B; Gycalpha63A; Gycalpha99B; SGCalpha; dgc1; dgca1; dgcalpha1; gycalpha; sGC-alpha; sGCalpha1; sGCalpha99B; sGC", "protein_names_uniprotkb": "Head-specific guanylate cyclase; 4.6.1.2; Dgcalpha1; Guanylyl cyclase alpha 1 subunit; Gycalpha99B", "protein_names_refseq": "CG1912-PA; Gycalpha99B-PA; guanyl cyclase alpha-subunit at 63A; guanylate cyclase 99B; guanylyl cyclase alpha-subunit at 99B; soluble guanylate cyclase; soluble guanylyl cyclase alpha", "tax_id": 7227, "disease": "withdrawal disorder (Disease Ontology:DOID:0060001); primary open angle glaucoma (Disease Ontology:DOID:1070); Moyamoya disease (Disease Ontology:DOID:13099)", "pathway": " (dme:Dmel_CG1912); (R-DME-445355)", "pathway_count": 2, "publication_count": 5, "publication_id_list": "10731132;12537569;12537572;7797526;8095978", "class_list": "", "function": "May have a role in phototransduction (PubMed:8095978). Catalyzes the conversion of GTP to cGMP, a common second messenger that is utilized in a wide variety of cells and signal transduction pathways (PubMed:7797526). A second subunit is required for enzyme activity (PubMed:7797526)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q24085;Q95SQ4", "ec_number_list": "4.6.1.2", "go_molecular_function": "GO:0004383 guanylate cyclase activity;GO:0005525 GTP binding;GO:0020037 heme binding", "go_cellular_component": "GO:0008074 guanylate cyclase complex, soluble", "go_biological_process": "GO:0035556 intracellular signal transduction;GO:0007601 visual perception;GO:0016056 G protein-coupled opsin signaling pathway;GO:0070482 response to oxygen levels;GO:0046956 positive phototaxis", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q07093-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q07407-1", "uniprot_id": "FGFR1_DROME", "mass": 82586.0, "length": 729, "protein_name": "Fibroblast growth factor receptor homolog 1", "gene_name": "htl", "organism": "Fruit fly", "refseq_name": "heartless, isoform B", "refseq_ac": "NP_524394", "gene_names_uniprotkb": "htl; CG7223; FR1; Tk1", "gene_names_refseq": "CG7223; CT22273; CT39172; DFGF-R1; DFGF-R2; DFR-1; DFR1/DFGF-R2; DFR1; DPR3; DTRK(FR1); Dfr-1; Dfr1; DmHD-38; Dmel\\CG7223; Dtk1; EMS2; FGF-R2; FGFR2; FGFR; FR1; Fr1; HD-38; HTL/FGFR1; Htl; Tk1; dtk1; htl; i100; i150; i79; j372", "protein_names_uniprotkb": "Fibroblast growth factor receptor homolog 1; 2.7.10.1; DmHD-38; Protein heartless; Tyrosine kinase 1; dTk1", "protein_names_refseq": "CG7223-PB; FGF receptor; fibroblast growth factor receptor 1; fibroblast growth factor receptor; heartless, isoform B; heartless; htl-PB", "tax_id": 7227, "disease": "idiopathic pulmonary fibrosis (Disease Ontology:DOID:0050156); lacrimoauriculodentodigital syndrome 1 (Disease Ontology:DOID:0050331); Beare-Stevenson cutis gyrata syndrome (Disease Ontology:DOID:0050660); autosomal dominant disease (Disease Ontology:DOID:0050736); limb ischemia (Disease Ontology:DOID:0050852); colorectal adenocarcinoma (Disease Ontology:DOID:0050861); oral squamous cell carcinoma (Disease Ontology:DOID:0050866); tonsil squamous cell carcinoma (Disease Ontology:DOID:0050920); scoliosis (Disease Ontology:DOID:0060249); atypical chronic myeloid leukemia, BCR-ABL1 negative (Disease Ontology:DOID:0060597); Muenke Syndrome (Disease Ontology:DOID:0060703); bent bone dysplasia syndrome 1 (Disease Ontology:DOID:0060992); myeloid neoplasm (Disease Ontology:DOID:0070004); bone disease (Disease Ontology:DOID:0080001); hypochondroplasia (Disease Ontology:DOID:0080041); Antley-Bixler syndrome (Disease Ontology:DOID:0081289); Antley-Bixler syndrome without disordered steroidogenesis (Disease Ontology:DOID:0081290); T-cell non-Hodgkin lymphoma (Disease Ontology:DOID:0081312); lacrimoauriculodentodigital syndrome 2 (Disease Ontology:DOID:0081371); hypogonadotropic hypogonadism 7 with or without anosmia (Disease Ontology:DOID:0090078); hypogonadotropic hypogonadism 2 with or without anosmia (Disease Ontology:DOID:0090083); SADDAN (Disease Ontology:DOID:0111158); camptodactyly-tall stature-scoliosis-hearing loss syndrome (Disease Ontology:DOID:0111160); Crouzon syndrome-acanthosis nigricans syndrome (Disease Ontology:DOID:0111161); epidermal nevus (Disease Ontology:DOID:0111162); Jackson-Weiss syndrome (Disease Ontology:DOID:0111337); osteoglophonic dysplasia (Disease Ontology:DOID:0111532); prostate cancer (Disease Ontology:DOID:10283); intestinal atresia (Disease Ontology:DOID:10486); stomach cancer (Disease Ontology:DOID:10534); retinitis pigmentosa (Disease Ontology:DOID:10584); Alzheimer's disease (Disease Ontology:DOID:10652); otitis media (Disease Ontology:DOID:10754); portal hypertension (Disease Ontology:DOID:10762); essential hypertension (Disease Ontology:DOID:10825); hypospadias (Disease Ontology:DOID:10892); urinary bladder cancer (Disease Ontology:DOID:11054); Human papillomavirus infectious disease (Disease Ontology:DOID:11166); sciatic neuropathy (Disease Ontology:DOID:11446); acoustic neuroma (Disease Ontology:DOID:12689); acrocephalosyndactylia (Disease Ontology:DOID:12960); thanatophoric dysplasia (Disease Ontology:DOID:13481); primary pulmonary hypertension (Disease Ontology:DOID:14557); Pfeiffer syndrome (Disease Ontology:DOID:14705); Saethre-Chotzen syndrome (Disease Ontology:DOID:14768); breast cancer (Disease Ontology:DOID:1612); squamous cell carcinoma (Disease Ontology:DOID:1749); colon cancer (Disease Ontology:DOID:219); transient cerebral ischemia (Disease Ontology:DOID:224); Crouzon syndrome (Disease Ontology:DOID:2339); craniosynostosis (Disease Ontology:DOID:2340); transitional cell carcinoma (Disease Ontology:DOID:2671); endometriosis (Disease Ontology:DOID:289); cervix carcinoma (Disease Ontology:DOID:2893); high grade glioma (Disease Ontology:DOID:3070); acanthosis nigricans (Disease Ontology:DOID:3138); chondrosarcoma (Disease Ontology:DOID:3371); esophagus squamous cell carcinoma (Disease Ontology:DOID:3748); lung squamous cell carcinoma (Disease Ontology:DOID:3907); lung non-small cell carcinoma (Disease Ontology:DOID:3908); lung adenocarcinoma (Disease Ontology:DOID:3910); Merkel cell carcinoma (Disease Ontology:DOID:3965); bladder urothelial carcinoma (Disease Ontology:DOID:4006); mouth disease (Disease Ontology:DOID:403); dysgerminoma (Disease Ontology:DOID:4441); renal cell carcinoma (Disease Ontology:DOID:4450); achondroplasia (Disease Ontology:DOID:4480); mesangial proliferative glomerulonephritis (Disease Ontology:DOID:4783); fibrolamellar carcinoma (Disease Ontology:DOID:5015); liver cirrhosis (Disease Ontology:DOID:5082); retinal detachment (Disease Ontology:DOID:5327); stomach carcinoma (Disease Ontology:DOID:5517); head and neck squamous cell carcinoma (Disease Ontology:DOID:5520); pulmonary hypertension (Disease Ontology:DOID:6432); hepatocellular carcinoma (Disease Ontology:DOID:684); female breast carcinoma (Disease Ontology:DOID:7843); osteoarthritis (Disease Ontology:DOID:8398); intestinal volvulus (Disease Ontology:DOID:8445); chronic myeloid leukemia (Disease Ontology:DOID:8552); Kaposi's sarcoma (Disease Ontology:DOID:8632); tongue cancer (Disease Ontology:DOID:8649); myeloid leukemia (Disease Ontology:DOID:8692); vascular dementia (Disease Ontology:DOID:8725); acute myeloid leukemia (Disease Ontology:DOID:9119); colorectal cancer (Disease Ontology:DOID:9256); nasopharynx carcinoma (Disease Ontology:DOID:9261); cleft lip (Disease Ontology:DOID:9296); steatotic liver disease (Disease Ontology:DOID:9452); obesity (Disease Ontology:DOID:9970)", "pathway": " (dme:Dmel_CG7223); (R-DME-109704); (R-DME-1257604); (R-DME-1307965); (R-DME-190322); (R-DME-190371); (R-DME-190372); (R-DME-190375); (R-DME-190377); (R-DME-5654221); (R-DME-5654227); (R-DME-5654228); (R-DME-5654695); (R-DME-5654699); (R-DME-5654700); (R-DME-5654704); (R-DME-5654706); (R-DME-5654710); (R-DME-5654712); (R-DME-5654719); (R-DME-5654720); (R-DME-5654727); (R-DME-5654732); (R-DME-5654733); (R-DME-5673001); (R-DME-6811558)", "pathway_count": 26, "publication_count": 7, "publication_id_list": "10731132;12537569;12537572;1915852;8112607;8330538;9731193", "class_list": "", "function": "May be required for patterning of muscle precursor cells. May be essential for generation of mesodermal and endodermal layers, invaginations of various types of cells and CNS formation., [UniProtKB, PubMed]", "predicted_glycosites": 10, "predicted_n_glycosites": 10, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 89, "glyco_site_count": 10, "binding_glycan_count": 0, "secondary_ac_list": "A4V320;O18371;Q26294;Q9VED5", "ec_number_list": "2.7.10.1;2.7.10.2;3.6.5.2;3.1.3.48;2.7.11.24;2.7.12.1;2.7.12.2;2.7.11.22;2.3.2.27;3.2.1.21;3.2.1.46;3.1.4.11;2.7.11.1", "go_molecular_function": "GO:0005007 fibroblast growth factor receptor activity;GO:0004713 protein tyrosine kinase activity;GO:0005524 ATP binding;GO:0004714 transmembrane receptor protein tyrosine kinase activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0043235 receptor complex;GO:0098975 postsynapse of neuromuscular junction", "go_biological_process": "GO:0007525 somatic muscle development;GO:0021782 glial cell development;GO:0001710 mesodermal cell fate commitment;GO:0007507 heart development;GO:0008284 positive regulation of cell population proliferation", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q07407-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q07886-1", "uniprot_id": "DDX49_DROME", "mass": 59678.0, "length": 521, "protein_name": "Probable ATP-dependent RNA helicase Dbp45A", "gene_name": "Dbp45A", "organism": "Fruit fly", "refseq_name": "DEAD box protein 45A", "refseq_ac": "NP_476927", "gene_names_uniprotkb": "Dbp45A; CG12759", "gene_names_refseq": "CG12759; DBP45A; DDX49; Dbp45A; Dbp45; DmRH18; Dmel\\CG12759; dbp45A", "protein_names_uniprotkb": "Probable ATP-dependent RNA helicase Dbp45A; 3.6.4.13; DEAD box protein 45A", "protein_names_refseq": "ATP-dependent RNA helicase; CG12759-PA; DEAD box protein 45A; Dbp45A-PA", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG12759); (R-DME-6791226)", "pathway_count": 2, "publication_count": 4, "publication_id_list": "10731132;12537569;12537572;7692973", "class_list": "", "function": "Probable ATP-binding RNA helicase., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9V528", "ec_number_list": "3.6.4.13;7.2.2.-;3.6.4.-;3.6.4.10;3.6.4.6;3.6.4.12;5.6.2.4;5.6.2.5;2.7.4.3;5.6.2.3;3.1.-.-;3.6.1.15;3.1.13.-;3.-.-.-;5.6.1.1;2.7.11.1;2.1.1.-;3.6.-.-;5.6.2.-", "go_molecular_function": "GO:0003723 RNA binding;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0003724 RNA helicase activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006364 rRNA processing;GO:0000381 regulation of alternative mRNA splicing, via spliceosome", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q07886-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q08832-1", "uniprot_id": "GBRB3_DROME", "mass": 56597.0, "length": 496, "protein_name": "Gamma-aminobutyric acid receptor subunit beta-like", "gene_name": "Lcch3", "organism": "Fruit fly", "refseq_name": "Ligand-gated chloride channel homolog 3", "refseq_ac": "NP_996469", "gene_names_uniprotkb": "Lcch3; CG17336", "gene_names_refseq": "CG17336; CT38330; DmGABAbeta; DmGA_b; Dmel\\CG17336; LCCH3; Lcch3", "protein_names_uniprotkb": "Gamma-aminobutyric acid receptor subunit beta-like; GABA(A) receptor", "protein_names_refseq": "CG17336-PC; GABA receptor beta subunit; Lcch3-PC; Ligand-gated chloride channel homolog 3; ligand-gated chloride channel homologue 3; ligand-gated chloride channel", "tax_id": 7227, "disease": "Lennox-Gastaut syndrome (Disease Ontology:DOID:0050561); fetal alcohol spectrum disorder (Disease Ontology:DOID:0050696); alcohol dependence (Disease Ontology:DOID:0050741); developmental disorder of mental health (Disease Ontology:DOID:0060037); autism spectrum disorder (Disease Ontology:DOID:0060041); developmental and epileptic encephalopathy 45 (Disease Ontology:DOID:0080428); developmental and epileptic encephalopathy 43 (Disease Ontology:DOID:0080447); developmental and epileptic encephalopathy 92 (Disease Ontology:DOID:0080471); autistic disorder (Disease Ontology:DOID:12849); hepatic encephalopathy (Disease Ontology:DOID:13413); alcohol use disorder (Disease Ontology:DOID:1574); depressive disorder (Disease Ontology:DOID:1596); status epilepticus (Disease Ontology:DOID:1824); childhood absence epilepsy (Disease Ontology:DOID:1825); epilepsy (Disease Ontology:DOID:1826); heroin dependence (Disease Ontology:DOID:9976)", "pathway": " (dme:Dmel_CG17336); (R-DME-977443)", "pathway_count": 2, "publication_count": 6, "publication_id_list": "10731132;12537569;12537572;15148245;7685594;8025558", "class_list": "", "function": "GABA, an inhibitory neurotransmitter, mediates neuronal inhibition by binding to the GABA receptor and opening an integral chloride channel. Combines with the ligand-gated ion channel subunit GRD to form cation-selective GABA-gated ion channels when coexpressed in Xenopus laevis oocytes., [UniProtKB, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 16, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "A4V4J6;Q9TX49;Q9VXL8", "ec_number_list": "", "go_molecular_function": "GO:0004890 GABA-A receptor activity;GO:0022851 GABA-gated chloride ion channel activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0045211 postsynaptic membrane;GO:0034707 chloride channel complex;GO:1902711 GABA-A receptor complex", "go_biological_process": "GO:1902476 chloride transmembrane transport;GO:0051932 synaptic transmission, GABAergic", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q08832-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q09147-1", "uniprot_id": "FGFR2_DROME", "mass": 117813.0, "length": 1052, "protein_name": "Fibroblast growth factor receptor homolog 2", "gene_name": "btl", "organism": "Fruit fly", "refseq_name": "breathless, isoform B", "refseq_ac": "NP_001014583", "gene_names_uniprotkb": "btl; CG32134; FR2; HD-311; Tk2", "gene_names_refseq": "0844/01; BTL/FGFR2; BTL; Btl; CG32134; CG6714; CT20816; D-FGFR; DFGF-R1; DFR2; Dfr-2; DmHD-311; Dmel\\CG32134; Dtk2; FGFR1; FGFR; Fgf-r; Fgfr; HD-311; Tk2; btl; dFGFR; dev; dtk2; fgf-r; l(3)00208; l(3)j2E11", "protein_names_uniprotkb": "Fibroblast growth factor receptor homolog 2; 2.7.10.1; Protein breathless; Tyrosine kinase 2; Tyrosine kinase receptor HD-311; dFGF-R1; dTk2", "protein_names_refseq": "CG32134-PB; FGF receptor; FGFR; Fibroblast-growth-factor-receptor; breathless, isoform B; breathless; btl-PB; devenir; fibrobast growth factor receptor; fibroblast growth factor receptor 1; fibroblast growth factor receptor; lethal (3) j2E11; no terminal cell clones-L", "tax_id": 7227, "disease": "idiopathic pulmonary fibrosis (Disease Ontology:DOID:0050156); lacrimoauriculodentodigital syndrome 1 (Disease Ontology:DOID:0050331); Beare-Stevenson cutis gyrata syndrome (Disease Ontology:DOID:0050660); autosomal dominant disease (Disease Ontology:DOID:0050736); limb ischemia (Disease Ontology:DOID:0050852); colorectal adenocarcinoma (Disease Ontology:DOID:0050861); oral squamous cell carcinoma (Disease Ontology:DOID:0050866); tonsil squamous cell carcinoma (Disease Ontology:DOID:0050920); scoliosis (Disease Ontology:DOID:0060249); atypical chronic myeloid leukemia, BCR-ABL1 negative (Disease Ontology:DOID:0060597); Muenke Syndrome (Disease Ontology:DOID:0060703); bent bone dysplasia syndrome 1 (Disease Ontology:DOID:0060992); myeloid neoplasm (Disease Ontology:DOID:0070004); bone disease (Disease Ontology:DOID:0080001); hypochondroplasia (Disease Ontology:DOID:0080041); Antley-Bixler syndrome (Disease Ontology:DOID:0081289); Antley-Bixler syndrome without disordered steroidogenesis (Disease Ontology:DOID:0081290); T-cell non-Hodgkin lymphoma (Disease Ontology:DOID:0081312); lacrimoauriculodentodigital syndrome 2 (Disease Ontology:DOID:0081371); hypogonadotropic hypogonadism 7 with or without anosmia (Disease Ontology:DOID:0090078); hypogonadotropic hypogonadism 2 with or without anosmia (Disease Ontology:DOID:0090083); SADDAN (Disease Ontology:DOID:0111158); camptodactyly-tall stature-scoliosis-hearing loss syndrome (Disease Ontology:DOID:0111160); Crouzon syndrome-acanthosis nigricans syndrome (Disease Ontology:DOID:0111161); epidermal nevus (Disease Ontology:DOID:0111162); Jackson-Weiss syndrome (Disease Ontology:DOID:0111337); osteoglophonic dysplasia (Disease Ontology:DOID:0111532); prostate cancer (Disease Ontology:DOID:10283); intestinal atresia (Disease Ontology:DOID:10486); stomach cancer (Disease Ontology:DOID:10534); retinitis pigmentosa (Disease Ontology:DOID:10584); Alzheimer's disease (Disease Ontology:DOID:10652); otitis media (Disease Ontology:DOID:10754); portal hypertension (Disease Ontology:DOID:10762); essential hypertension (Disease Ontology:DOID:10825); hypospadias (Disease Ontology:DOID:10892); urinary bladder cancer (Disease Ontology:DOID:11054); Human papillomavirus infectious disease (Disease Ontology:DOID:11166); sciatic neuropathy (Disease Ontology:DOID:11446); acoustic neuroma (Disease Ontology:DOID:12689); acrocephalosyndactylia (Disease Ontology:DOID:12960); thanatophoric dysplasia (Disease Ontology:DOID:13481); primary pulmonary hypertension (Disease Ontology:DOID:14557); Pfeiffer syndrome (Disease Ontology:DOID:14705); Saethre-Chotzen syndrome (Disease Ontology:DOID:14768); breast cancer (Disease Ontology:DOID:1612); squamous cell carcinoma (Disease Ontology:DOID:1749); colon cancer (Disease Ontology:DOID:219); transient cerebral ischemia (Disease Ontology:DOID:224); Crouzon syndrome (Disease Ontology:DOID:2339); craniosynostosis (Disease Ontology:DOID:2340); transitional cell carcinoma (Disease Ontology:DOID:2671); endometriosis (Disease Ontology:DOID:289); cervix carcinoma (Disease Ontology:DOID:2893); acanthosis nigricans (Disease Ontology:DOID:3138); chondrosarcoma (Disease Ontology:DOID:3371); esophagus squamous cell carcinoma (Disease Ontology:DOID:3748); lung squamous cell carcinoma (Disease Ontology:DOID:3907); lung non-small cell carcinoma (Disease Ontology:DOID:3908); lung adenocarcinoma (Disease Ontology:DOID:3910); Merkel cell carcinoma (Disease Ontology:DOID:3965); bladder urothelial carcinoma (Disease Ontology:DOID:4006); mouth disease (Disease Ontology:DOID:403); dysgerminoma (Disease Ontology:DOID:4441); renal cell carcinoma (Disease Ontology:DOID:4450); achondroplasia (Disease Ontology:DOID:4480); mesangial proliferative glomerulonephritis (Disease Ontology:DOID:4783); fibrolamellar carcinoma (Disease Ontology:DOID:5015); liver cirrhosis (Disease Ontology:DOID:5082); retinal detachment (Disease Ontology:DOID:5327); stomach carcinoma (Disease Ontology:DOID:5517); head and neck squamous cell carcinoma (Disease Ontology:DOID:5520); pulmonary hypertension (Disease Ontology:DOID:6432); hepatocellular carcinoma (Disease Ontology:DOID:684); female breast carcinoma (Disease Ontology:DOID:7843); osteoarthritis (Disease Ontology:DOID:8398); intestinal volvulus (Disease Ontology:DOID:8445); chronic myeloid leukemia (Disease Ontology:DOID:8552); Kaposi's sarcoma (Disease Ontology:DOID:8632); tongue cancer (Disease Ontology:DOID:8649); myeloid leukemia (Disease Ontology:DOID:8692); vascular dementia (Disease Ontology:DOID:8725); acute myeloid leukemia (Disease Ontology:DOID:9119); colorectal cancer (Disease Ontology:DOID:9256); nasopharynx carcinoma (Disease Ontology:DOID:9261); cleft lip (Disease Ontology:DOID:9296); steatotic liver disease (Disease Ontology:DOID:9452); obesity (Disease Ontology:DOID:9970)", "pathway": " (dme:Dmel_CG32134); (R-DME-109704); (R-DME-1257604); (R-DME-1307965); (R-DME-190322); (R-DME-190370); (R-DME-190371); (R-DME-190372); (R-DME-190373); (R-DME-190374); (R-DME-190375); (R-DME-190377); (R-DME-445144); (R-DME-5654219); (R-DME-5654221); (R-DME-5654227); (R-DME-5654228); (R-DME-5654687); (R-DME-5654688); (R-DME-5654689); (R-DME-5654693); (R-DME-5654695); (R-DME-5654699); (R-DME-5654700); (R-DME-5654704); (R-DME-5654706); (R-DME-5654710); (R-DME-5654712); (R-DME-5654719); (R-DME-5654720); (R-DME-5654726); (R-DME-5654727); (R-DME-5654732); (R-DME-5654733); (R-DME-5673001); (R-DME-6811558)", "pathway_count": 36, "publication_count": 7, "publication_id_list": "10731132;12537572;1325393;1849109;1915852;8330538;9731193", "class_list": "", "function": "May be required for patterning of muscle precursor cells: generation of mesodermal and endodermal layers, invaginations of various types of cells, and CNS formation. Essential for the ability of the migrating tracheal and midline cells to recognize external guiding cues., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 15, "predicted_n_glycosites": 15, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 88, "glyco_site_count": 15, "binding_glycan_count": 0, "secondary_ac_list": "A4V1Y3;Q712V2;Q9VUC8", "ec_number_list": "2.7.10.1;2.7.10.2;3.6.5.2;3.1.3.48;2.7.11.24;2.7.12.1;2.7.12.2;2.7.11.22;2.3.2.27;3.2.1.21;3.2.1.46;3.1.4.11;2.7.11.1", "go_molecular_function": "GO:0005007 fibroblast growth factor receptor activity;GO:0005524 ATP binding;GO:0004714 transmembrane receptor protein tyrosine kinase activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0043235 receptor complex;GO:0035230 cytoneme", "go_biological_process": "GO:0008284 positive regulation of cell population proliferation;GO:0043410 positive regulation of MAPK cascade;GO:0046847 filopodium assembly;GO:0045887 positive regulation of synaptic assembly at neuromuscular junction;GO:0060446 branching involved in open tracheal system development", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q09147-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q0E961-1", "uniprot_id": "BDGED_DROME", "mass": 146659.0, "length": 1331, "protein_name": "Sodium-dependent transporter bedraggled", "gene_name": "bdg", "organism": "Fruit fly", "refseq_name": "bedraggled, isoform A", "refseq_ac": "NP_611064", "gene_names_uniprotkb": "bdg; CG8291", "gene_names_refseq": "CG8291; Dmel\\CG8291; bdg", "protein_names_uniprotkb": "Sodium-dependent transporter bedraggled", "protein_names_refseq": "CG8291-PA; bdg-PA; bedraggled, isoform A", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG8291); (R-DME-352230); (R-DME-442660)", "pathway_count": 3, "publication_count": 3, "publication_id_list": "10731132;12537572;17890365", "class_list": "", "function": "Putative sodium-dependent transporter which is required for viability, early imaginal disk development and adult motor coordination (PubMed:17890365). Also has a role in the fate commitment of the R3/R4 photoreceptor cells (PubMed:17890365). May function in ommatidial polarity by regulating the activity of the core polarity genes, acting upstream of (or in parallel to) Vang, dsh, pk, stan, and dgo, but downstream or independently of fz (PubMed:17890365)., [UniProtKB, PubMed]", "predicted_glycosites": 7, "predicted_n_glycosites": 5, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 7, "binding_glycan_count": 0, "secondary_ac_list": "A0A0B4LF97", "ec_number_list": "", "go_molecular_function": "GO:0005326 neurotransmitter transmembrane transporter activity;GO:0015179 L-amino acid transmembrane transporter activity;GO:0005328 neurotransmitter:sodium symporter activity;GO:0005283 amino acid:sodium symporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane", "go_biological_process": "GO:0035725 sodium ion transmembrane transport;GO:0006836 neurotransmitter transport;GO:1903804 glycine import across plasma membrane;GO:0007464 R3/R4 cell fate commitment", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q0E961-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q0KHT7-1", "uniprot_id": "DAPKR_DROME", "mass": 73001.0, "length": 674, "protein_name": "Death-associated protein kinase related", "gene_name": "Drak", "organism": "Fruit fly", "refseq_name": "Death-associated protein kinase related, isoform C", "refseq_ac": "NP_001162723", "gene_names_uniprotkb": "Drak; CG32666", "gene_names_refseq": "CG11713; CG1760; CG32666; DRak; Dmel\\CG32666; Drak; EP(X)1452; EP1452; drak", "protein_names_uniprotkb": "Death-associated protein kinase related; 2.7.11.1", "protein_names_refseq": "CG32666-PC; Death-associated protein kinase related, isoform C; Drak-PC", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG32666)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "10731132;12537572;18327897", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "E1JJH9;Q86P19", "ec_number_list": "2.7.11.17;2.7.11.1;2.7.11.13;2.7.11.24;2.7.11.22;2.7.11.21;5.6.1.8;2.7.11.11;2.7.11.23;2.7.12.1;2.7.11.25;2.7.11.12;2.7.12.2;2.7.10.2;2.7.11.39", "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0035556 intracellular signal transduction;GO:0043065 positive regulation of apoptotic process;GO:0002009 morphogenesis of an epithelium;GO:0007476 imaginal disc-derived wing morphogenesis;GO:0007480 imaginal disc-derived leg morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q0KHT7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q24020-1", "uniprot_id": "FLII_DROME", "mass": 143682.0, "length": 1256, "protein_name": "Protein flightless-1", "gene_name": "fliI", "organism": "Fruit fly", "refseq_name": "flightless I", "refseq_ac": "NP_525097", "gene_names_uniprotkb": "fliI; CG1484", "gene_names_refseq": "15; BcDNA:LD21753; CG1484; CT3691; DCA3-19; Dmel\\CG1484; EN3; FLI-I; Fli-I; W2; fli I; fli-I; fliI; fli; fltI; fltO; l(1)18-80; l(1)19Fd; l(1)ESHS53; l(1)W-2; lDCB2-19; sdby; w-2", "protein_names_uniprotkb": "Protein flightless-1; Flightless-I", "protein_names_refseq": "CG1484-PA; Flightless-I; fliI-PA; flightless I; flightless-1; flightless; gluful-2; lgluful-2; section 15; standby", "tax_id": 7227, "disease": "dilated cardiomyopathy (Disease Ontology:DOID:12930); obesity (Disease Ontology:DOID:9970)", "pathway": " (dme:Dmel_CG1484)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "10731132;10731138;12537572;8248259;8582612;9520435", "class_list": "", "function": "May play a key role in embryonic cellularization by interacting with both the cytoskeleton and other cellular components. Alternatively, it may play a structural role in indirect flight muscle. Vital for embryonic development., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q24088;Q9VRH0", "ec_number_list": "", "go_molecular_function": "GO:0003779 actin binding;GO:0005546 phosphatidylinositol-4,5-bisphosphate binding;GO:0051015 actin filament binding;GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005634 nucleus;GO:0015629 actin cytoskeleton;GO:0030018 Z disc", "go_biological_process": "GO:0051016 barbed-end actin filament capping;GO:0008154 actin polymerization or depolymerization;GO:0051014 actin filament severing;GO:0030239 myofibril assembly;GO:0007527 adult somatic muscle development", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q24020-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q24046-1", "uniprot_id": "ATPB1_DROME", "mass": 35309.0, "length": 309, "protein_name": "Sodium/potassium-transporting ATPase subunit beta-1", "gene_name": "nrv1", "organism": "Fruit fly", "refseq_name": "nervana 1, isoform B", "refseq_ac": "NP_001260163", "gene_names_uniprotkb": "nrv1; CG9258", "gene_names_refseq": "42kDa; CG9258; Dmel\\CG9258; K-ATPase; NKA-alpha; NaK ATPase; Na[+]/K[+] ATPase; Na[+]/K[+]-ATPase; Na[+]/K[+]ATPase; Na; Nrv1; Nrv; nervana; nrv1", "protein_names_uniprotkb": "Sodium/potassium-transporting ATPase subunit beta-1; Protein nervana 1; Sodium/potassium-dependent ATPase subunit beta-1", "protein_names_refseq": "CG9258-PB; Nervana1; nervana 1, isoform B; nervana 1; nervous system antigen 1; nirvana 1; nirvana; nrv1-PB", "tax_id": 7227, "disease": "autoimmune gastritis (Disease Ontology:DOID:0040090); sensorineural hearing loss (Disease Ontology:DOID:10003); stomach cancer (Disease Ontology:DOID:10534); essential hypertension (Disease Ontology:DOID:10825); atrophic gastritis (Disease Ontology:DOID:8929); obesity (Disease Ontology:DOID:9970)", "pathway": " (dme:Dmel_CG9258); (R-DME-210991); (R-DME-2173795)", "pathway_count": 3, "publication_count": 8, "publication_id_list": "10731132;12537569;12537572;17606467;17893096;7540667;7777518;9648860", "class_list": "", "function": "This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 2, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 2, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 2, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 6, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "Q8MR34;Q9VM86", "ec_number_list": "", "go_molecular_function": "GO:0001671 ATPase activator activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005890 sodium:potassium-exchanging ATPase complex", "go_biological_process": "GO:0006812 monoatomic cation transport;GO:0006883 intracellular sodium ion homeostasis;GO:0030007 intracellular potassium ion homeostasis;GO:0036376 sodium ion export across plasma membrane;GO:1990573 potassium ion import across plasma membrane", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "Q24046-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q24049-1", "uniprot_id": "AMN_DROME", "mass": 20399.0, "length": 180, "protein_name": "Amnesiac neuropeptides", "gene_name": "amn", "organism": "Fruit fly", "refseq_name": "amnesiac", "refseq_ac": "NP_523416", "gene_names_uniprotkb": "amn; CG11937", "gene_names_refseq": "Amn; Anm; CG11937; Dmel\\CG11937; Drm-amn; EP(X)1442; PACAP-38; PACAP-like; PACAP38-like; PACAP38; PACAP; Pacap38; amn; chpd; dAmn", "protein_names_uniprotkb": "Amnesiac neuropeptides", "protein_names_refseq": "CG11937-PA; amn-PA; amnesiac; cheap date; cheapdate; pituitary adenylyl cyclase-activating polypeptide-like; pituitary adenylyl cyclase-activating polypeptide", "tax_id": 7227, "disease": "alcohol use disorder (Disease Ontology:DOID:1574)", "pathway": " (dme:Dmel_CG11937)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "10516293;10731132;11114336;11517334;12270109;12537572;7754370", "class_list": "", "function": "Required for associative learning and memory in adults. Expression pattern suggests a modulatory role in memory formation. Controls neurotransmitter-mediated signaling pathways associated with the structure of the larval peripheral nerve., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9VWC1", "ec_number_list": "", "go_molecular_function": "GO:0005184 neuropeptide hormone activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0008049 male courtship behavior;GO:0007218 neuropeptide signaling pathway;GO:0007611 learning or memory;GO:0007613 memory;GO:0048149 behavioral response to ethanol", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q24049-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q24090-1", "uniprot_id": "Q24090_DROME", "mass": 41911.0, "length": 370, "protein_name": "Snf5-related 1", "gene_name": "Snr1", "organism": "Fruit fly", "refseq_name": "Snf5-related 1", "refseq_ac": "NP_730935", "gene_names_uniprotkb": "Snr1; BAP45; CG1064; Dmel\\CG1064; Dmel_CG1064; SNR1; Snr-1; Snr; l(3)01319; snr-1; snr1; snr", "gene_names_refseq": "BAP45; CG1064; Dmel\\CG1064; SNR1; Snr-1; Snr1/BAP45; Snr1; Snr; l(3)01319; snr-1; snr1; snr", "protein_names_uniprotkb": "Snf5-related 1", "protein_names_refseq": "CG1064-PA; Snf5-related 1; Snr1-PA; snf-related1", "tax_id": 7227, "disease": "colorectal adenocarcinoma (Disease Ontology:DOID:0050861); Coffin-Siris syndrome 3 (Disease Ontology:DOID:0070045); schwannomatosis 1 (Disease Ontology:DOID:0070480); rhabdoid tumor predisposition syndrome 1 (Disease Ontology:DOID:0070618); sinonasal undifferentiated carcinoma (Disease Ontology:DOID:0080799); vestibular schwannomatosis (Disease Ontology:DOID:0111252); atypical teratoid rhabdoid tumor (Disease Ontology:DOID:2129); schwannomatosis (Disease Ontology:DOID:3204); meningioma (Disease Ontology:DOID:3565); rhabdoid cancer (Disease Ontology:DOID:3672); clear cell renal cell carcinoma (Disease Ontology:DOID:4467); synovial sarcoma (Disease Ontology:DOID:5485); epithelioid sarcoma (Disease Ontology:DOID:6193); hepatocellular carcinoma (Disease Ontology:DOID:684)", "pathway": " (dme:Dmel_CG1064); (R-DME-3214858); (R-DME-8939243); (R-DME-9933937); (R-DME-9933939); (R-DME-9933946); (R-DME-9934037)", "pathway_count": 7, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 14, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0003713 transcription coactivator activity;GO:0030957 Tat protein binding;GO:0070984 SET domain binding", "go_cellular_component": "GO:0005634 nucleus;GO:0071564 npBAF complex;GO:0071565 nBAF complex;GO:0000228 nuclear chromosome;GO:0035060 brahma complex", "go_biological_process": "GO:0006338 chromatin remodeling;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0008285 negative regulation of cell population proliferation;GO:0045893 positive regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q24090-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q24114-1", "uniprot_id": "DALY_DROME", "mass": 69031.0, "length": 626, "protein_name": "Division abnormally delayed protein", "gene_name": "dally", "organism": "Fruit fly", "refseq_name": "division abnormally delayed, isoform B", "refseq_ac": "NP_001246685", "gene_names_uniprotkb": "dally; CG4974", "gene_names_refseq": "CG4974; CT15952; Dally; Dmel\\CG4974; anon-EST:Liang-1.63; clone 1.63; dally; gem; l(3)06464; l(3)SG18", "protein_names_uniprotkb": "Division abnormally delayed protein; Dally protein", "protein_names_refseq": "CG4974-PB; dally-PB; division abnormally delayed, isoform B; division abnormally delayed; genitalia missing; lethal (3) SG18", "tax_id": 7227, "disease": "Simpson-Golabi-Behmel syndrome type 1 (Disease Ontology:DOID:0060248); atypical teratoid rhabdoid tumor (Disease Ontology:DOID:2129); nephroblastoma (Disease Ontology:DOID:2154); placental site trophoblastic tumor (Disease Ontology:DOID:3596); liver cirrhosis (Disease Ontology:DOID:5082); hepatocellular carcinoma (Disease Ontology:DOID:684); hepatoblastoma (Disease Ontology:DOID:687)", "pathway": " (dme:Dmel_CG4974); (R-DME-1971475); (R-DME-2022928); (R-DME-2024096); (R-DME-209471); (R-DME-381426); (R-DME-5362798); (R-DME-8957275); (R-DME-9769739)", "pathway_count": 9, "publication_count": 17, "publication_id_list": "10549295;10619433;10731132;11395778;11486055;11861468;12537572;14729575;15189162;15563523;15875013;18198278;19349973;35301437;35609633;8582281;8824192", "class_list": "", "function": "Cell surface proteoglycan that bears heparan sulfate (PubMed:35609633, PubMed:8582281). Functions as a coreceptor for growth factors and morphogens, such as the products of dpp, to regulate signaling and distribution of these ligands (PubMed:35609633, PubMed:8582281). Required for cell division patterning during postembryonic development of the nervous system (PubMed:8582281). Plays a role in dpp/BMP signaling possibly by stabilizing dpp and thereby creating a morphological gradient during wing development (PubMed:35609633). Might have a role in testis development (PubMed:35609633). Functions with magu and fwe in a mechanism of scaling, which utilises apoptosis to ensure that the dpp patterning gradient remains proportional to the size of the growing wing (PubMed:35301437). In this mechanism, fwe represses dally and Magu-dependent activity in expanding the gradient, and dally/Magu inhibits fwe-dependent apoptosis to keep cell death rate low (PubMed:35301437). When the levels of these different proteins are optimally regulated the gradient correctly scales with organ growth but when this fails, fwe-mediated apoptosis is activated to trim the developing tissue to match the correct size of the gradient (PubMed:35301437)., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 6, "predicted_n_glycosites": 2, "predicted_o_glycosites": 4, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 2, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 2, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 2, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 3, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 7, "glyco_site_count": 8, "binding_glycan_count": 0, "secondary_ac_list": "Q9VSQ8", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane;GO:0009986 cell surface;GO:0016323 basolateral plasma membrane;GO:0031012 extracellular matrix;GO:0009897 external side of plasma membrane", "go_biological_process": "GO:0008052 sensory organ boundary specification;GO:0045880 positive regulation of smoothened signaling pathway;GO:0048749 compound eye development;GO:0007409 axonogenesis;GO:0016477 cell migration", "synthesized_glycan_count": 0, "hit_score": 2.0, "record_id": "Q24114-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q24133-1", "uniprot_id": "DNAJ1_DROME", "mass": 37028.0, "length": 334, "protein_name": "DnaJ protein homolog 1", "gene_name": "DnaJ-1", "organism": "Fruit fly", "refseq_name": "DnaJ-like-1, isoform A", "refseq_ac": "NP_523936", "gene_names_uniprotkb": "DnaJ-1; CG10578; DNAJ-1; DNAJ1; DROJ1; DmHsp40; Dmel\\CG10578; Dmel_CG10578; DnaJ1 64EF; DnaJ1; Dnaj-1; DroJ1; EU3500; HDJ1; HSP40; Hdj1; Hsp-40; Hsp40; anon-WO0140519.166; anon-WO0172774.135; dHDJ1; dHSP40; dHdj1; dhdJ1; dhdj-1; dhdj1; dnaJ-1; dnaj-1; droj1; hsp40", "gene_names_refseq": "CG10578; DNAJ-1; DNAJ1; DROJ1; DmHsp40; Dmel\\CG10578; DnaJ-1; DnaJ1 64EF; DnaJ1; Dnaj-1; DroJ1; EU3500; HSP40/HDJ1; HSP40; Hdj1; Hsp-40; Hsp40; anon-WO0140519.166; anon-WO0172774.135; dHDJ1/HSP40; dHDJ1; dHSP40; dHdj1; dhdJ1; dhdj-1; dhdj1; dnaJ-1; dnaj-1; droj1; hsp40", "protein_names_uniprotkb": "DnaJ protein homolog 1; DROJ1", "protein_names_refseq": "CG10578-PA; DnaJ-1-PA; DnaJ-like-1, isoform A; Hsp40; dnaJ like1", "tax_id": 7227, "disease": "congenital myopathy 21 (Disease Ontology:DOID:0081353); autosomal dominant limb-girdle muscular dystrophy type 1 (Disease Ontology:DOID:0110305); distal myopathy (Disease Ontology:DOID:11720)", "pathway": " (dme:Dmel_CG10578)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;18327897;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9VRP0", "ec_number_list": "", "go_molecular_function": "GO:0051082 unfolded protein binding;GO:0051087 protein-folding chaperone binding;GO:0140297 DNA-binding transcription factor binding", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0050821 protein stabilization;GO:0006457 protein folding;GO:0009408 response to heat;GO:0042691 positive regulation of crystal cell differentiation", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "Q24133-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q24152-1", "uniprot_id": "CKS1_DROME", "mass": 9122.0, "length": 74, "protein_name": "Cyclin-dependent kinases regulatory subunit", "gene_name": "Cks30A", "organism": "Fruit fly", "refseq_name": "Cyclin-dependent kinase subunit 30A", "refseq_ac": "NP_476947", "gene_names_uniprotkb": "Cks30A; CDI2; CG3738; Cks1; Cks", "gene_names_refseq": "CDI2; CG3738; Cdi2; Cks30A; Cks; DmCks1; Dmel\\CG3738; U40077; cdi2; cks30A; cks; fs(2)rem; rem", "protein_names_uniprotkb": "Cyclin-dependent kinases regulatory subunit", "protein_names_refseq": "CG3738-PA; Cks30A-PA; Cyclin-dependent kinase interactor 2; Cyclin-dependent kinase subunit 30A; remnants", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG3738); (R-DME-187577); (R-DME-69231)", "pathway_count": 3, "publication_count": 4, "publication_id_list": "10731132;12537569;12537572;7809159", "class_list": "", "function": "Binds to the catalytic subunit of the cyclin dependent kinases Cdk1 and Cdk2, and is essential for their biological function., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9VLD0", "ec_number_list": "", "go_molecular_function": "GO:0019901 protein kinase binding;GO:0042393 histone binding;GO:0043130 ubiquitin binding;GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity", "go_cellular_component": "GO:0019005 SCF ubiquitin ligase complex;GO:0000307 cyclin-dependent protein kinase holoenzyme complex", "go_biological_process": "GO:0007144 female meiosis I;GO:0051301 cell division;GO:0007346 regulation of mitotic cell cycle;GO:0007143 female meiotic nuclear division;GO:0031145 anaphase-promoting complex-dependent catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q24152-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q24157-1", "uniprot_id": "BRN_DROME", "mass": 37620.0, "length": 325, "protein_name": "Beta-1,4-mannosylglycolipid beta-1,3-N-acetylglucosaminyltransferase brn", "gene_name": "brn", "organism": "Fruit fly", "refseq_name": "brainiac", "refseq_ac": "NP_476901", "gene_names_uniprotkb": "brn; CG4934", "gene_names_refseq": "Brn; CG4934; Dmel\\CG4934; EG:EG0007.6; brc; brn; fs(1)107; fs(1)A107; l(1)6P6", "protein_names_uniprotkb": "Beta-1,4-mannosylglycolipid beta-1,3-N-acetylglucosaminyltransferase brn; 2.4.1.-; Glycolipid-specific beta-1,3-N-Acetylglucosaminyltransferase brn; Neurogenic secreted-signaling protein brn; Protein brainiac; UDP-GlcNAc:beta-Man/beta-Gal beta-1,3GlcNAc transferase; beta3GlcNAc-transferase", "protein_names_refseq": "CG4934-PA; brainiac; brn-PA; gene B", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG4934); (R-DME-2022854); (R-DME-9037629); (R-DME-913709); (R-DME-9840309)", "pathway_count": 5, "publication_count": 13, "publication_id_list": "10731132;10731137;12130631;12130651;12454022;12537569;12537572;1483386;15611100;16182276;17498683;8812107;9012507", "class_list": "", "function": "A beta-1,3 glycosyltransferase that catalyzes the transfer of N-acetylglucosamine (GlcNAc) from UDP-GlcNAc in a beta-1,3 linkage to the Man(beta1-4)Glc disaccharide core of glycosphingolipids (PubMed:12130631, PubMed:12130651). Involved in the biosynthesis of arthroseries glycosphingolipids downstream of egh/egghead; required for sequential elongation steps (PubMed:12130631, PubMed:12130651, PubMed:12454022, PubMed:15611100). Catalyzes addition of the third monosaccharide residue to form the trihexosylceramide glycolipid GlcNAc(beta1-3)Man(beta1-4)Glc(beta1-1)Cer (PubMed:12130631, PubMed:12130651). Highly specific for disaccharide structures containing D-mannose but also active to a lesser extent on structures containing L-fucose or D-galactose (probably not under physiological conditions) (PubMed:12130651, PubMed:15611100). Neurogenic protein implicated in epithelial development (PubMed:9012507). Required in the female germline for establishing and maintaining the follicular epithelium throughout oogenesis (PubMed:8812107, PubMed:9012507). Collaborates with Notch on the apical surface of follicle cells to mediate germline-follicle cell adhesion (PubMed:9012507). Involved in dorsoventral patterning of the ovarian follicle (PubMed:1483386). Required, along with egh, in the lobula complex primordium for establishment of the lamina/lobula cortex boundary and correct targeting of photoreceptor (R-cell) neuron axons (PubMed:16182276). Downstream glycosphingolipid biosynthesis by beta4GalNAcTA is involved in motor coordination and locomotion (PubMed:17498683). Downstream glycosphingolipid biosynthesis by beta4GalNAcTB is involved in oocyte dorsal follicular cell fate specification by EGFR signaling (PubMed:17498683)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 3, "predicted_n_glycosites": 2, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "Q5BIH4;Q8SZS9;Q9W4N0", "ec_number_list": "2.4.1.-", "go_molecular_function": "GO:0008194 UDP-glycosyltransferase activity;GO:0046981 beta-1,4-mannosylglycolipid beta-1,3-N-acetylglucosaminyltransferase activity", "go_cellular_component": "GO:0000139 Golgi membrane", "go_biological_process": "GO:0006688 glycosphingolipid biosynthetic process;GO:0007219 Notch signaling pathway;GO:0009101 glycoprotein biosynthetic process;GO:0007299 follicle cell of egg chamber-cell adhesion;GO:0007293 germarium-derived egg chamber formation", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "Q24157-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q24185-1", "uniprot_id": "HOOK_DROME", "mass": 76665.0, "length": 679, "protein_name": "Protein hook", "gene_name": "hook", "organism": "Fruit fly", "refseq_name": "hook", "refseq_ac": "NP_476573", "gene_names_uniprotkb": "hook; CG10653; hk", "gene_names_refseq": "CG10653; Dmel\\CG10653; Hook; dHk; hk; hook", "protein_names_uniprotkb": "Protein hook; dHK", "protein_names_refseq": "CG10653-PA; hook-PA; hook", "tax_id": 7227, "disease": "Emery-Dreifuss muscular dystrophy (Disease Ontology:DOID:11726)", "pathway": " (dme:Dmel_CG10653)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "10198042;10731132;11018772;11238449;12537569;12537572;17435236;8682859;9927460", "class_list": "", "function": "Involved in endocytic trafficking by stabilizing organelles of the endocytic pathway. Probably acts as a cytoskeletal linker protein required to tether endosome vesicles to the cytoskeleton. Involved in modulation of endocytosis at stages required for down-regulation of membrane proteins that control synapse size. Not involved in synaptic vesicle recycling. Required in R7 cells for boss endocytosis into multivesicular bodies (MVBs). Has a role in regulating adult longevity., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9VJ15", "ec_number_list": "", "go_molecular_function": "GO:0008017 microtubule binding;GO:0031267 small GTPase binding;GO:0051959 dynein light intermediate chain binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005768 endosome;GO:0005813 centrosome;GO:0005874 microtubule;GO:0045202 synapse", "go_biological_process": "GO:0006897 endocytosis;GO:0030705 cytoskeleton-dependent intracellular transport;GO:0008340 determination of adult lifespan;GO:0031122 cytoplasmic microtubule organization", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "Q24185-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q24238-1", "uniprot_id": "APH4_DROME", "mass": 65262.0, "length": 596, "protein_name": "Alkaline phosphatase 4", "gene_name": "Alp4", "organism": "Fruit fly", "refseq_name": "alkaline phosphatase 4, isoform A", "refseq_ac": "NP_524601", "gene_names_uniprotkb": "Alp4; CG1462; aph-4", "gene_names_refseq": "Alp4; Aph-4; CG1462; Dmel\\CG1462; aph-4; l(3)07028; pMY51", "protein_names_uniprotkb": "Alkaline phosphatase 4; 3.1.3.1", "protein_names_refseq": "Alp4-PA; CG1462-PA; alkaline phosphatase 4, isoform A; alkaline phosphatase-4", "tax_id": 7227, "disease": "inflammatory bowel disease (Disease Ontology:DOID:0050589); adult hypophosphatasia (Disease Ontology:DOID:0110913); infantile hypophosphatasia (Disease Ontology:DOID:0110914); childhood hypophosphatasia (Disease Ontology:DOID:0110915); uremia (Disease Ontology:DOID:4676); ulcerative colitis (Disease Ontology:DOID:8577); Crohn's disease (Disease Ontology:DOID:8778)", "pathway": " (dme:Dmel_CG1462); (R-DME-1483166); (R-DME-6811438); (R-DME-8935690)", "pathway_count": 4, "publication_count": 4, "publication_id_list": "10628988;10731132;12537569;12537572", "class_list": "", "function": "Important role in neural and renal epithelial function., [UniProtKB, PubMed]", "predicted_glycosites": 5, "predicted_n_glycosites": 5, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 7, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "B9EQR2;Q3KN28;Q8IMH0;Q8SXW6;Q9VA19", "ec_number_list": "3.1.3.1;3.6.5.2;3.1.3.2;3.1.3.48", "go_molecular_function": "GO:0004035 alkaline phosphatase activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0005615 extracellular space;GO:0005886 plasma membrane;GO:0009986 cell surface;GO:0098552 side of membrane", "go_biological_process": "GO:0042045 epithelial fluid transport;GO:0007399 nervous system development;GO:0007618 mating", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q24238-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q24246-11", "uniprot_id": "DYIN_DROME", "mass": 73917.0, "length": 663, "protein_name": "Cytoplasmic dynein 1 intermediate chain", "gene_name": "sw", "organism": "Fruit fly", "refseq_name": "short wing, isoform N", "refseq_ac": "NP_001285486", "gene_names_uniprotkb": "sw; CG18000; Cdic; Dic19B", "gene_names_refseq": "17-234; CG18000; Cdic2b; Cdic; DIC; Dic19B; Dic19C; Dic; Dmel\\CG18000; IC74; IC; cDIC; dic; l(1)19Bb; sw CES; sw", "protein_names_uniprotkb": "Cytoplasmic dynein 1 intermediate chain; DH IC; Dynein intermediate chain, cytosolic; Protein short wing", "protein_names_refseq": "CG18000-PN; cytoplasmic dynein intermediate chain; cytoplasmic dynein intermediate polypeptide chain; cytoplasmic dynein; dynein IC; dynein intermediate chain; dynein intermediate-chain; dynein; short wing, isoform N; sw-PN; swallow", "tax_id": 7227, "disease": "autosomal recessive primary microcephaly (Disease Ontology:DOID:0070296)", "pathway": " (dme:Dmel_CG18000); (R-DME-3371497); (R-DME-6807878); (R-DME-6811436); (R-DME-9646399)", "pathway_count": 5, "publication_count": 4, "publication_id_list": "10731132;11071907;12537572;9774695", "class_list": "", "function": "Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chains mediate the help dynein bind to dynactin 150 kDa component (By similarity)., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "O96508;O96510;O96511;O96512;O96513;O96514;O96515;O96516;Q5U0Z1;Q86BQ5;Q9NG49;Q9TZR7;Q9TZR8;Q9TZR9;Q9TZS0;Q9VR78", "ec_number_list": "", "go_molecular_function": "GO:0060090 molecular adaptor activity;GO:0034452 dynactin binding;GO:0045503 dynein light chain binding;GO:0045504 dynein heavy chain binding", "go_cellular_component": "GO:0005874 microtubule;GO:0031965 nuclear membrane;GO:0005765 lysosomal membrane;GO:0043005 neuron projection;GO:0005868 cytoplasmic dynein complex", "go_biological_process": "GO:0008088 axo-dendritic transport;GO:0007018 microtubule-based movement;GO:0000226 microtubule cytoskeleton organization;GO:0007051 spindle organization;GO:0010970 transport along microtubule", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q24246-11", "record_type": "protein" }, { "uniprot_canonical_ac": "Q24247-1", "uniprot_id": "ITA1_DROME", "mass": 127973.0, "length": 1146, "protein_name": "Integrin alpha-PS1", "gene_name": "mew", "organism": "Fruit fly", "refseq_name": "multiple edematous wings, isoform E", "refseq_ac": "NP_001259503", "gene_names_uniprotkb": "mew; CG1771; CT5254; Dmel\\CG1771; Dmel_CG1771; Integrin alpha PS1; ItgaPS1; Mew; PS1alpha; PS1; PSalpha1; aPS1; alpha integrin; alpha-PS1; alpha1Int; alphaPS1; alpha[[PS1]]; l(1)G0429; l(1)G0443", "gene_names_refseq": "CG1771; CT5254; Dmel\\CG1771; Integrin alpha PS1; ItgaPS1; Mew; PS1alpha; PS1; PSalpha1; aPS1; alpha integrin; alpha-PS1; alpha1Int; alphaPS1; alpha[[PS1]]; l(1)G0429; l(1)G0443; mew", "protein_names_uniprotkb": "Integrin alpha-PS1; Position-specific antigen subunit alpha-1; Protein multiple edematous wings", "protein_names_refseq": "CG1771-PE; PS I alpha; PS1 integrin; PS1-Integrin; Position-specific-1 antigen; Position-specific-antigen-1alpha; alpha integrin; alpha-PS1-integrin; alpha1 integrin subunit; alpha1 integrin; alphaPS integrin; alphaPS1 integrin; alpha[[PS1]] subunit of integrin; integrin PSII alpha subunit; integrin alpha PS1; integrin alphaPS1 subunit; integrin alphaPS1; mew-PE; multiple edematous wings, isoform E; multiple edematous wings", "tax_id": 7227, "disease": "cardiomyopathy (Disease Ontology:DOID:0050700); junctional epidermolysis bullosa with pyloric atresia (Disease Ontology:DOID:0060733); junctional epidermolysis bullosa Herlitz type (Disease Ontology:DOID:0060737); muscular disease (Disease Ontology:DOID:0080000); congenital muscular dystrophy due to integrin alpha-7 deficiency (Disease Ontology:DOID:0110639); Duchenne muscular dystrophy (Disease Ontology:DOID:11723); cancer (Disease Ontology:DOID:162); epilepsy (Disease Ontology:DOID:1826); arteriosclerosis (Disease Ontology:DOID:2349); glomerulonephritis (Disease Ontology:DOID:2921); junctional epidermolysis bullosa (Disease Ontology:DOID:3209); myocardial infarction (Disease Ontology:DOID:5844)", "pathway": " (dme:Dmel_CG1771); (R-DME-198933); (R-DME-202733); (R-DME-210991); (R-DME-216083); (R-DME-3000170); (R-DME-445144); (R-DME-445355); (R-DME-446107); (R-DME-6798695)", "pathway_count": 10, "publication_count": 18, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;17893096;19035354;19349973;25589440;26109356;26109357;40245499;7972082;8240969", "class_list": "", "function": "Integrin alpha-PS1/beta-PS is a receptor for laminin., [UniProtKB, PubMed]", "predicted_glycosites": 7, "predicted_n_glycosites": 7, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 5, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 5, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 5, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 12, "glyco_site_count": 13, "binding_glycan_count": 0, "secondary_ac_list": "M9PEG3;M9PHG7;M9PJL8;Q8SY51;Q9VYF6", "ec_number_list": "", "go_molecular_function": "GO:0046982 protein heterodimerization activity;GO:0050839 cell adhesion molecule binding;GO:0050840 extracellular matrix binding;GO:0038023 signaling receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005925 focal adhesion;GO:0009986 cell surface;GO:0016324 apical plasma membrane;GO:0016328 lateral plasma membrane", "go_biological_process": "GO:0007015 actin filament organization;GO:0007155 cell adhesion;GO:0007229 integrin-mediated signaling pathway;GO:0016477 cell migration;GO:0030154 cell differentiation", "synthesized_glycan_count": 0, "hit_score": 2.6, "record_id": "Q24247-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q24307-1", "uniprot_id": "DIAP2_DROME", "mass": 54538.0, "length": 498, "protein_name": "Death-associated inhibitor of apoptosis 2", "gene_name": "Diap2", "organism": "Fruit fly", "refseq_name": "Death-associated inhibitor of apoptosis 2, isoform A", "refseq_ac": "NP_477127", "gene_names_uniprotkb": "Diap2; CG8293; DIHA; Iap2; Ilp", "gene_names_refseq": "CG8293; D-IAP2; D-iap2; DIAP-2; DIAP1; DIAP2; DIAPII; DIAP; DIHA; Diap-2; Diap2; Diap; Diha; Dmel\\CG8293; IAP2; IAP; Iap2; Ilp; dIAP2; dIAP; dILP; diap2", "protein_names_uniprotkb": "Death-associated inhibitor of apoptosis 2; Apoptosis 2 inhibitor; IAP homolog A; IAP-like protein; ILP; Inhibitor of apoptosis 2; dILP", "protein_names_refseq": "CG8293-PA; Death-associated inhibitor of apoptosis 2, isoform A; Diap2-PA; IAP-like protein; drosophila inhibitor of apoptosis 2; drosophila melanogaster inhibitor of apoptosis 2; inhibitor of apoptosis protein 2", "tax_id": 7227, "disease": "colorectal adenoma (Disease Ontology:DOID:0050860); colorectal adenocarcinoma (Disease Ontology:DOID:0050861); tongue squamous cell carcinoma (Disease Ontology:DOID:0050865); oral squamous cell carcinoma (Disease Ontology:DOID:0050866); extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (Disease Ontology:DOID:0050909); X-linked lymphoproliferative syndrome 2 (Disease Ontology:DOID:0060706); metabolic dysfunction and alcohol associated liver disease (Disease Ontology:DOID:0070508); colorectal carcinoma (Disease Ontology:DOID:0080199); metabolic dysfunction-associated steatohepatitis (Disease Ontology:DOID:0080547); prostate cancer (Disease Ontology:DOID:10283); breast cancer (Disease Ontology:DOID:1612); colon cancer (Disease Ontology:DOID:219); breast ductal carcinoma (Disease Ontology:DOID:3007); cervical squamous cell carcinoma (Disease Ontology:DOID:3744); lung non-small cell carcinoma (Disease Ontology:DOID:3908); cervical cancer (Disease Ontology:DOID:4362); renal cell carcinoma (Disease Ontology:DOID:4450); esophagus adenocarcinoma (Disease Ontology:DOID:4914); gallbladder carcinoma (Disease Ontology:DOID:4948); hepatocellular carcinoma (Disease Ontology:DOID:684); cervix uteri carcinoma in situ (Disease Ontology:DOID:8991); colorectal cancer (Disease Ontology:DOID:9256)", "pathway": " (dme:Dmel_CG8293); (R-DME-111459); (R-DME-111465); (R-DME-111469); (R-DME-209447); (R-DME-214399); (R-DME-3769402); (R-DME-5675482); (R-DME-8948747); (R-DME-8948751); (R-DME-9627069); (R-DME-9958825)", "pathway_count": 12, "publication_count": 21, "publication_id_list": "10731132;11018014;11550090;12537569;12537572;12732719;14519762;16081424;16311020;16894030;17068333;17158449;18166655;19217783;20888210;22549468;24374974;8548811;8552191;8643514;8654366", "class_list": "", "function": "Required for activation of NF-kappaB transcription factors in the immune deficiency (Imd) signaling cascade which is essential for innate immune responses upon infection by Gram-negative bacteria (PubMed:16894030, PubMed:17068333). Promotes cytoplasmic cleavage of Rel and its translocation to the nucleus where it drives expression of antimicrobial peptides (PubMed:17068333, PubMed:24374974). Binds, polyubiquitinates and activates Dredd which is required for Rel-mediated induction of antimicrobial peptides (PubMed:22549468). Anti-apoptotic protein which binds, ubiquitinates and inactivates the effector caspase Drice (PubMed:18166655). Suppresses rpr and hid-dependent cell death in the eye (PubMed:8548811). However, has also been shown to have little, if any, role in the regulation of the canonical caspase-dependent apoptosis pathway (PubMed:17068333). Plays a role in regulating the expression of ion channels (PubMed:24374974)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 7, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 22, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A4UZI4;Q24115;Q24149;Q24177;Q960U3;Q9V7G1", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0031625 ubiquitin protein ligase binding;GO:0061630 ubiquitin protein ligase activity;GO:0004842 ubiquitin-protein transferase activity;GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "GO:0043066 negative regulation of apoptotic process;GO:0045087 innate immune response;GO:0050829 defense response to Gram-negative bacterium;GO:0006915 apoptotic process;GO:0016567 protein ubiquitination", "synthesized_glycan_count": 0, "hit_score": 2.2, "record_id": "Q24307-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q24311-1", "uniprot_id": "CUL1_DROME", "mass": 89511.0, "length": 774, "protein_name": "Cullin homolog 1", "gene_name": "Cul1", "organism": "Fruit fly", "refseq_name": "cullin 1, isoform D", "refseq_ac": "NP_523655", "gene_names_uniprotkb": "Cul1; CG1877; cul-1; lin19", "gene_names_refseq": "CG1877; CUL1; Cul-1; Cul1; Cullin-1; Cullin1; Dmel\\CG1877; Lin-19; Lin19; Q9V312; cul-1; cul1; dCUL1; dCul-1; dCul1; dmCUL1; l(2)02074; l(2)k01207; lin 19; lin-19/cul-1; lin19-like; lin19", "protein_names_uniprotkb": "Cullin homolog 1; Lin-19 homolog protein", "protein_names_refseq": "CG1877-PD; Cul1-PD; SCF-betaTrCP complex; cullin 1, isoform D; cullin-1; cullin1; dCullin1; lin-19-like; lin19-like", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG1877); (R-DME-1169091); (R-DME-174113); (R-DME-187577); (R-DME-195253); (R-DME-202424); (R-DME-209360); (R-DME-209461); (R-DME-2565942); (R-DME-2871837); (R-DME-5607761); (R-DME-5607764); (R-DME-5610780); (R-DME-5610785); (R-DME-5676590); (R-DME-68949); (R-DME-69231); (R-DME-69601); (R-DME-8854050); (R-DME-8939902); (R-DME-8951664); (R-DME-9020702); (R-DME-917937); (R-DME-9762114); (R-DME-983168)", "pathway_count": 25, "publication_count": 19, "publication_id_list": "10102270;10458606;10731132;11500045;12183637;12231619;12537572;16299518;16326393;16386907;17925225;18493598;20123973;20392747;24068890;24413555;27331610;27692068;9215627", "class_list": "", "function": "Core component of multiple SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as a rigid scaffold that organizes the SKP1-F-box protein and RBX1 subunits. May contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. During early metamorphosis, part of the SCF-slmb complex that negatively regulates the InR/PI3K/TOR pathway to activate the pruning of unnecessary larval ddaC dendrites and mushroom body axons (PubMed:24068890). The SCF-slmb complex also regulates asymmetrical division of neuroblasts and inhibits ectopic neuroblast formation partly through SAK and Akt1 (PubMed:24413555). Also part of an SCF complex required for caspase activation during sperm differentiation (PubMed:20392747). Necessary for auditory transduction: plays a role in Johnston's organ organization by acting in the regulation of zip and ck function in scolopidial apical attachment (PubMed:27331610). May function by acting in a Ubr3-mediated pathway that negatively regulates the ubiquitination of zip, consequently affecting its interaction with ck (PubMed:27331610)., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A4UZ78;Q0E9G0;Q9V312", "ec_number_list": "", "go_molecular_function": "GO:0031625 ubiquitin protein ligase binding;GO:0160072 ubiquitin ligase complex scaffold activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0019005 SCF ubiquitin ligase complex", "go_biological_process": "GO:0046627 negative regulation of insulin receptor signaling pathway;GO:0043066 negative regulation of apoptotic process;GO:0090090 negative regulation of canonical Wnt signaling pathway;GO:0016567 protein ubiquitination;GO:0031398 positive regulation of protein ubiquitination", "synthesized_glycan_count": 0, "hit_score": 2.0, "record_id": "Q24311-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q24324-1", "uniprot_id": "DSOR1_DROME", "mass": 43870.0, "length": 396, "protein_name": "Dual specificity mitogen-activated protein kinase kinase dSOR1", "gene_name": "Dsor1", "organism": "Fruit fly", "refseq_name": "downstream of raf1, isoform B", "refseq_ac": "NP_001285044", "gene_names_uniprotkb": "Dsor1; 2; CG15793; D-MEK; D-Mek; D-SOR; D-Sor; D-mek; D-sor-1; D-sor; DMEK-1; DRODSOR1; DSOR1; DSORT; DSOR; DSor1; DSor; Dmek; Dmel\\CG15793; Dmel_CG15793; Dsor1; Dsor; EK1-1; MAPKK; MEK1; MEK; Mek; SOR; Sor; Su(Raf)34B; dMEK; dMek; dSor1; dSor; dsor1; dsor; mek; sor", "gene_names_refseq": "CG15793; D-MEK/Dsor; D-MEK; D-Mek; D-SOR; D-Sor; D-mek; D-sor-1; D-sor; DMEK-1; DRODSOR1; DSOR1; DSORT; DSOR; DSor1; DSor; Dmek; Dmel\\CG15793; Dsor1; Dsor; EK1-1; MAPKK; MEK/Dsor1; MEK1/2; MEK; Mek1/2; Mek; SOR; Sor; Su(Raf)34B; dMEK; dMek; dSor1; dSor; dsor1; dsor; mek; sor/MEK1; sor", "protein_names_uniprotkb": "Dual specificity mitogen-activated protein kinase kinase dSOR1; 2.7.12.2; Downstream of RAF; MAPKK", "protein_names_refseq": "CG15793-PB; Dsor1-PB; MAPK kinase; Map kinase kinase; dSor1; downstream of Raf1; downstream of raf1, isoform B; downstream suppressor of Raf 1; drosophila MEK; mitogen-activated protein kinase kinase", "tax_id": 7227, "disease": "cardiofaciocutaneous syndrome (Disease Ontology:DOID:0060233); RASopathy (Disease Ontology:DOID:0080690); cardiofaciocutaneous syndrome 3 (Disease Ontology:DOID:0111462); cardiofaciocutaneous syndrome 4 (Disease Ontology:DOID:0111463); breast cancer (Disease Ontology:DOID:1612); cancer (Disease Ontology:DOID:162); prostate adenocarcinoma (Disease Ontology:DOID:2526); glioblastoma (Disease Ontology:DOID:3068); high grade glioma (Disease Ontology:DOID:3070); lung adenocarcinoma (Disease Ontology:DOID:3910); ovarian carcinoma (Disease Ontology:DOID:4001); pancreatic adenocarcinoma (Disease Ontology:DOID:4074); melorheostosis (Disease Ontology:DOID:4253); renal cell carcinoma (Disease Ontology:DOID:4450); small intestine adenocarcinoma (Disease Ontology:DOID:4906); hepatocellular carcinoma (Disease Ontology:DOID:684); cataract (Disease Ontology:DOID:83)", "pathway": " (dme:Dmel_CG15793); (R-DME-110056); (R-DME-112411); (R-DME-170968); (R-DME-209190); (R-DME-209214); (R-DME-432553); (R-DME-445144); (R-DME-5673000); (R-DME-5674135); (R-DME-5674499)", "pathway_count": 11, "publication_count": 56, "publication_id_list": "10409506;10477300;10557210;10731132;11430804;11440719;11912487;11955435;12122057;12432393;12442174;12447397;12537568;12537569;12537572;12537573;12537574;12563262;12663920;12694293;12944510;14759367;15300262;15563523;15592457;15598741;15616566;15875013;16041759;16110336;16319317;16326393;16410523;16630821;17077139;17418796;17569856;17569867;17925225;18593878;18815259;25589440;26109356;26109357;29433126;40245499;7481773;8381718;8596938;8600384;8898207;8906787;8906794;8938123;9482888;9674431", "class_list": "", "function": "Required downstream of Raf in the sevenless (sev), torso (tor), and Drosophila EGF receptor homolog (DER) signal transduction pathways. Involved in both positive regulation (at the posterior terminus) and negative regulation (at the anterior domain) of tll, as in other terminal class gene products, maybe via the ERK-A kinase., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 3, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 3, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 3, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 17, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "Q8ISE0;Q9W360", "ec_number_list": "2.7.11.17;2.7.11.1;2.7.11.13;2.7.11.24;2.7.10.1;2.7.11.22;2.7.11.21;2.7.10.2;3.6.5.2;5.6.1.8;2.7.11.11;2.7.11.23;3.1.3.16;2.7.12.1;2.7.11.25;2.7.11.12;2.7.12.2;2.7.11.39", "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0004713 protein tyrosine kinase activity;GO:0005524 ATP binding;GO:0019900 kinase binding;GO:0004708 MAP kinase kinase activity", "go_cellular_component": "GO:0005829 cytosol;GO:0000793 condensed chromosome", "go_biological_process": "GO:0051607 defense response to virus;GO:0000165 MAPK cascade;GO:0007173 epidermal growth factor receptor signaling pathway;GO:0070371 ERK1 and ERK2 cascade;GO:0008286 insulin receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 6.1, "record_id": "Q24324-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q24342-1", "uniprot_id": "FNG_DROME", "mass": 46992.0, "length": 412, "protein_name": "Fringe glycosyltransferase", "gene_name": "fng", "organism": "Fruit fly", "refseq_name": "fringe", "refseq_ac": "NP_524191", "gene_names_uniprotkb": "fng; CG10580", "gene_names_refseq": "CG10580; D-Fng; D-fng; Dfng; Dmel\\CG10580; Fng; Frg; Fringe; fg; fng; frg; l(3)rG554", "protein_names_uniprotkb": "Fringe glycosyltransferase; 2.4.1.222; O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase", "protein_names_refseq": "CG10580-PA; beta3-N-acetylglucosaminyltransferase; fng-PA; fringe", "tax_id": 7227, "disease": "spondylocostal dysostosis 3 (Disease Ontology:DOID:0112361)", "pathway": " (dme:Dmel_CG10580)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "10731132;10899003;10935626;10935637;10985380;12537569;12537572;7954826;9019410;9187150", "class_list": "", "function": "Glycosyltransferase involved in the elongation of O-linked ligands to activate Notch signaling. Possesses fucose-specific beta-1,3-N-acetylglucosaminyltransferase activity; extends the O-linked fucose on the Notch EGF repeats. Boundary-specific cell-signaling molecule that is responsible for dorsal-ventral cell interactions during wing development., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9VP97", "ec_number_list": "2.4.1.222", "go_molecular_function": "GO:0046872 metal ion binding;GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005737 cytoplasm;GO:0005797 Golgi medial cisterna;GO:0005795 Golgi stack", "go_biological_process": "GO:0048749 compound eye development;GO:0045747 positive regulation of Notch signaling pathway;GO:0045746 negative regulation of Notch signaling pathway;GO:0036066 protein O-linked glycosylation via fucose;GO:0008593 regulation of Notch signaling pathway", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "Q24342-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q24388-1", "uniprot_id": "LSP2_DROME", "mass": 83349.0, "length": 701, "protein_name": "Larval serum protein 2", "gene_name": "Lsp2", "organism": "Fruit fly", "refseq_name": "larval serum protein 2, isoform B", "refseq_ac": "NP_001287042", "gene_names_uniprotkb": "Lsp2; C23; CG11538; CG6806; DmeLSP2; Dmel\\CG6806; Dmel_CG6806; LHP; LSP 2; LSP-2; LSP2; Lsp-2; Pt-1; lsp2", "gene_names_refseq": "C23; CG11538; CG6806; DmeLSP2; Dmel\\CG6806; LHP; LSP 2; LSP-2; LSP2; Lsp-2; Lsp2; Pt-1; lsp2", "protein_names_uniprotkb": "Larval serum protein 2; Hexamerin-2; LSP-2", "protein_names_refseq": "CG6806-PB; Lsp2-PB; Protein-1; larval serum protein 2, isoform B; larval serum protein 2; larval serum protein-2; larval-hemolymph-protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG6806)", "pathway_count": 1, "publication_count": 14, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357;33925313;9128741", "class_list": "", "function": "Larval storage protein (LSP) which may serve as a store of amino acids for synthesis of adult proteins., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 1, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "Q9VTT8", "ec_number_list": "", "go_molecular_function": "GO:0045735 nutrient reservoir activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005616 larval serum protein complex", "go_biological_process": "GO:0097009 energy homeostasis;GO:0008045 motor neuron axon guidance;GO:0016201 synaptic target inhibition", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "Q24388-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q24439-1", "uniprot_id": "ATPO_DROME", "mass": 22422.0, "length": 209, "protein_name": "ATP synthase subunit O, mitochondrial", "gene_name": "ATPsynO", "organism": "Fruit fly", "refseq_name": "ATP synthase, oligomycin sensitivity conferring protein", "refseq_ac": "NP_524358", "gene_names_uniprotkb": "ATPsynO; CG4307; Oscp", "gene_names_refseq": "ATPO_DROME; ATPO; ATPsynO; CG4307; Dmel\\CG4307; OSCP; Oscp; dATPsynO; oscp", "protein_names_uniprotkb": "ATP synthase subunit O, mitochondrial; OSCP; Oligomycin sensitivity conferral protein", "protein_names_refseq": "ATP synthase oligomycin sensitivity conferral protein; ATP synthase, oligomycin sensitivity conferring protein; ATPsynO-PA; CG4307-PA; F0/F1 ATP synthase OSCP; OLIGOMYCIN SENSITIVITY CONFERRING PROTEIN; oligimycin sensitive-conferring protein; oligomycin sensitivity conferring protein precursor; oligomycin sensitivity-conferring protein", "tax_id": 7227, "disease": "mitochondrial complex V (ATP synthase) deficiency nuclear type 7 (Disease Ontology:DOID:0070464); Alzheimer's disease (Disease Ontology:DOID:10652); hypothyroidism (Disease Ontology:DOID:1459); Leigh disease (Disease Ontology:DOID:3652); clear cell renal cell carcinoma (Disease Ontology:DOID:4467)", "pathway": " (dme:Dmel_CG4307); (R-DME-163210); (R-DME-8949613); (R-DME-9837999)", "pathway_count": 4, "publication_count": 4, "publication_id_list": "10071211;10731132;12537569;12537572", "class_list": "", "function": "Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9VFA4", "ec_number_list": "", "go_molecular_function": "GO:0046933 proton-transporting ATP synthase activity, rotational mechanism", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane;GO:0045259 proton-transporting ATP synthase complex", "go_biological_process": "GO:0015986 proton motive force-driven ATP synthesis;GO:0042776 proton motive force-driven mitochondrial ATP synthesis;GO:1902600 proton transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q24439-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q24523-4", "uniprot_id": "BUN2_DROME", "mass": 138064.0, "length": 1331, "protein_name": "Protein bunched, class 2/F/G isoform", "gene_name": "bun", "organism": "Fruit fly", "refseq_name": "bunched, isoform G", "refseq_ac": "NP_001036357", "gene_names_uniprotkb": "bun; CG42281; shs", "gene_names_refseq": "1550; BunA; Bun; CG31857; CG42281; CG5461; Dm_2L:60722; Dmel\\CG42281; EP(2)0488; TSC-22; Tsc22; bnc; bun; l(2)00255; l(2)02687; l(2)05479; l(2)06475; l(2)k02903; l(2)rI043; shs", "protein_names_uniprotkb": "Protein bunched, class 2/F/G isoform; Protein shortsighted", "protein_names_refseq": "CG42281-PG; bun-PG; bunched, isoform G; bunched; short sighted; short-sighted; shortsighted", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG42281)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "10731132;12537572;7555710", "class_list": "", "function": "Probable transcription factor required for peripheral nervous system morphogenesis, eye development and oogenesis. May be required for the transmission of the dpp signal and for a morphogenetic movement of the medulla in the brain that reorients the second optic lobe relative to the first. Plays a role in determining proper dorsal cell fates leading to the formation of the dorsal appendages., [UniProtKB, PubMed]", "predicted_glycosites": 4, "predicted_n_glycosites": 0, "predicted_o_glycosites": 4, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "D4G7A9;Q0E8R0;Q9VK78;Q9VK79", "ec_number_list": "", "go_molecular_function": "GO:0042803 protein homodimerization activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0008284 positive regulation of cell population proliferation;GO:0030307 positive regulation of cell growth;GO:0043066 negative regulation of apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q24523-4", "record_type": "protein" }, { "uniprot_canonical_ac": "Q24592-1", "uniprot_id": "JAK_DROME", "mass": 135062.0, "length": 1177, "protein_name": "Tyrosine-protein kinase hopscotch", "gene_name": "hop", "organism": "Fruit fly", "refseq_name": "hopscotch", "refseq_ac": "NP_511119", "gene_names_uniprotkb": "hop; CG1594; HD-160", "gene_names_refseq": "4; CG1594; Dm JAK; DmHD-160; Dmel\\CG1594; HD-160; HOP; Hop1; Hop2; Hop; Hpo; JAK; Jak; L4; Tum-1; Tum; d-jak; hop/JAK; hop; jak; l(1)10Be; l(1)G18; l(1)L4; l(1)hop; msvl", "protein_names_uniprotkb": "Tyrosine-protein kinase hopscotch; 2.7.10.2", "protein_names_refseq": "CG1594-PA; Hop; JAK kinase; Janus-family kinase; hop-PA; hopscotch; hopskotch; janus kinase; locus 18; tumorous", "tax_id": 7227, "disease": "juvenile myelomonocytic leukemia (Disease Ontology:DOID:0050458); adult T-cell leukemia/lymphoma (Disease Ontology:DOID:0050523); tongue squamous cell carcinoma (Disease Ontology:DOID:0050865); stroke (Disease Ontology:DOID:0051061); familial erythrocytosis 1 (Disease Ontology:DOID:0060652); thrombosis (Disease Ontology:DOID:0060903); myeloid neoplasm (Disease Ontology:DOID:0070004); colorectal carcinoma (Disease Ontology:DOID:0080199); metabolic dysfunction-associated steatotic liver disease (Disease Ontology:DOID:0080208); T-cell prolymphocytic leukemia (Disease Ontology:DOID:0081042); graft-versus-host disease (Disease Ontology:DOID:0081267); T-cell non-Hodgkin lymphoma (Disease Ontology:DOID:0081312); severe combined immunodeficiency 104 (Disease Ontology:DOID:0090014); immunodeficiency 35 (Disease Ontology:DOID:0111989); prostate cancer (Disease Ontology:DOID:10283); stomach cancer (Disease Ontology:DOID:10534); portal hypertension (Disease Ontology:DOID:10762); esophageal carcinoma (Disease Ontology:DOID:1107); heart disease (Disease Ontology:DOID:114); sciatic neuropathy (Disease Ontology:DOID:11446); Budd-Chiari syndrome (Disease Ontology:DOID:11512); primary biliary cholangitis (Disease Ontology:DOID:12236); leukemia (Disease Ontology:DOID:1240); endometrial cancer (Disease Ontology:DOID:1380); alcoholic liver cirrhosis (Disease Ontology:DOID:14018); disease of cellular proliferation (Disease Ontology:DOID:14566); limited scleroderma (Disease Ontology:DOID:1577); cancer (Disease Ontology:DOID:162); hyperuricemia (Disease Ontology:DOID:1920); atherosclerosis (Disease Ontology:DOID:1936); colon cancer (Disease Ontology:DOID:219); essential thrombocythemia (Disease Ontology:DOID:2224); myeloproliferative neoplasm (Disease Ontology:DOID:2226); thrombocytosis (Disease Ontology:DOID:2228); transient cerebral ischemia (Disease Ontology:DOID:224); colon adenocarcinoma (Disease Ontology:DOID:234); ovarian cancer (Disease Ontology:DOID:2394); hematologic cancer (Disease Ontology:DOID:2531); pancreatic ductal adenocarcinoma (Disease Ontology:DOID:3498); liver cancer (Disease Ontology:DOID:3571); esophagus squamous cell carcinoma (Disease Ontology:DOID:3748); lung carcinoma (Disease Ontology:DOID:3905); lung non-small cell carcinoma (Disease Ontology:DOID:3908); lung adenocarcinoma (Disease Ontology:DOID:3910); bacterial gastritis (Disease Ontology:DOID:4033); pancreatic adenocarcinoma (Disease Ontology:DOID:4074); myelofibrosis (Disease Ontology:DOID:4971); liver cirrhosis (Disease Ontology:DOID:5082); retinal detachment (Disease Ontology:DOID:5327); T-cell acute lymphoblastic leukemia (Disease Ontology:DOID:5603); myocardial infarction (Disease Ontology:DOID:5844); severe combined immunodeficiency (Disease Ontology:DOID:627); hepatocellular carcinoma (Disease Ontology:DOID:684); ankylosing spondylitis (Disease Ontology:DOID:7147); ulcerative colitis (Disease Ontology:DOID:8577); acute megakaryocytic leukemia (Disease Ontology:DOID:8761); Crohn's disease (Disease Ontology:DOID:8778); polycythemia vera (Disease Ontology:DOID:8997); systemic lupus erythematosus (Disease Ontology:DOID:9074); acute myeloid leukemia (Disease Ontology:DOID:9119); colorectal cancer (Disease Ontology:DOID:9256); nasopharynx carcinoma (Disease Ontology:DOID:9261); obesity (Disease Ontology:DOID:9970)", "pathway": " (dme:Dmel_CG1594); (R-DME-1266695); (R-DME-209209); (R-DME-209228); (R-DME-210688); (R-DME-5673000); (R-DME-6785807); (R-DME-69231); (R-DME-8985947); (R-DME-9020558); (R-DME-983231)", "pathway_count": 11, "publication_count": 23, "publication_id_list": "10731132;10823841;11825879;12537569;12537572;12783781;12967563;15925495;16055650;16094372;16129580;16277982;16477645;18327897;21186352;8314084;8463208;8608596;9047382;9620640;9671298;9731193;9784499", "class_list": "", "function": "Tyrosine kinase of the non-receptor type, phosphorylates the marelle protein. Required maternally for the establishment of the normal array of embryonic segments: involved in the control of pair-rule gene transcription in a stripe-specific manner. Together with Hsp83 and piwi, mediates canalization, also known as developmental robustness, likely via epigenetic silencing of existing genetic variants and suppression of transposon-induced new genetic variation., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 63, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q712V3;Q8SZI9;Q9VYZ7", "ec_number_list": "2.7.11.1;2.7.10.1;2.7.10.2;3.6.5.2;2.7.12.1;2.7.11.17;2.7.12.2;2.7.11.22", "go_molecular_function": "GO:0004713 protein tyrosine kinase activity;GO:0004715 non-membrane spanning protein tyrosine kinase activity;GO:0005524 ATP binding;GO:0005126 cytokine receptor binding", "go_cellular_component": "GO:0005829 cytosol;GO:0012505 endomembrane system;GO:0009898 cytoplasmic side of plasma membrane", "go_biological_process": "GO:0007442 hindgut morphogenesis;GO:0048749 compound eye development;GO:0006351 DNA-templated transcription;GO:0007399 nervous system development;GO:0030154 cell differentiation", "synthesized_glycan_count": 0, "hit_score": 2.4, "record_id": "Q24592-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q26365-1", "uniprot_id": "ADT_DROME", "mass": 34215.0, "length": 312, "protein_name": "ADP/ATP translocase", "gene_name": "sesB", "organism": "Fruit fly", "refseq_name": "stress-sensitive B, isoform E", "refseq_ac": "NP_001285090", "gene_names_uniprotkb": "sesB; A-T; ADT2; ANT1; ANT; ATP translocase; CG16944; Dmel\\CG16944; Dmel_CG16944; EM12; Hmr; S12; SESB; SesB; anon-WO02059370.55; dANT; dSLC25A4; jive; l(1)9Ed; l(1)9Fa; l(1)DC701; l(1)EM31; l(1)G0126; l(1)G0247; l(1)G0386; l(1)S12; orangi; ses B; sesB; sesb", "gene_names_refseq": "A/A-T/sesB; A/A-T; ADP/ATP translocase; ADT2; ANT1; ANT; CG16944; Dmel\\CG16944; EM12; Hmr; S12; SESB; SesB; anon-WO02059370.55; dANT; dSLC25A4; jive; l(1)9Ed; l(1)9Fa; l(1)DC701; l(1)EM31; l(1)G0126; l(1)G0247; l(1)G0386; l(1)S12; orangi; ses B; sesB; sesb", "protein_names_uniprotkb": "ADP/ATP translocase; ADP,ATP carrier protein; ANT; Adenine nucleotide translocator; Stress-sensitive protein B", "protein_names_refseq": "ADP,ATP carrier protein; CG16944-PE; Stress-sensitive B; adenine nuclear translocase; adenine nucleotide translocase; drosophila ANT; lethal(1)9Ed; sesB-PE; stress sensitive B; stress-sensitive B, isoform E; stress-sensitive", "tax_id": 7227, "disease": "mitochondrial DNA depletion syndrome 12a (Disease Ontology:DOID:0080130); mitochondrial DNA depletion syndrome 12b (Disease Ontology:DOID:0080335); dilated cardiomyopathy 1H (Disease Ontology:DOID:0110429); autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions 2 (Disease Ontology:DOID:0111517); Alzheimer's disease (Disease Ontology:DOID:10652); facioscapulohumeral muscular dystrophy (Disease Ontology:DOID:11727); hypertrophic cardiomyopathy (Disease Ontology:DOID:11984); chronic progressive external ophthalmoplegia (Disease Ontology:DOID:12558); alcoholic cardiomyopathy (Disease Ontology:DOID:12935); epilepsy (Disease Ontology:DOID:1826); mitochondrial myopathy (Disease Ontology:DOID:699); mitochondrial metabolism disease (Disease Ontology:DOID:700)", "pathway": " (dme:Dmel_CG16944); (R-DME-1268020); (R-DME-83936); (R-DME-9837999)", "pathway_count": 4, "publication_count": 15, "publication_id_list": "10511565;10731132;12537568;12537569;12537572;12537573;12537574;1387687;16110336;17569856;17569867;25589440;26109356;26109357;7520869", "class_list": "", "function": "ADP:ATP antiporter that mediates import of ADP into the mitochondrial matrix for ATP synthesis, and export of ATP out to fuel the cell (By similarity). Cycles between the cytoplasmic-open state (c-state) and the matrix-open state (m-state): operates by the alternating access mechanism with a single substrate-binding site intermittently exposed to either the cytosolic (c-state) or matrix (m-state) side of the inner mitochondrial membrane (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Catalyzes the exchange of ADP and ATP across the membrane., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 12, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A4V491;P91614;Q0KHU3;Q26254;Q53XG6;Q8IRA0;Q95S30;Q9VZ70", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0005471 ATP:ADP antiporter activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane;GO:0045202 synapse;GO:0005757 mitochondrial permeability transition pore complex", "go_biological_process": "GO:2001171 positive regulation of ATP biosynthetic process;GO:0051900 regulation of mitochondrial depolarization;GO:0006839 mitochondrial transport;GO:0046716 muscle cell cellular homeostasis;GO:0051124 synaptic assembly at neuromuscular junction", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "Q26365-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q26416-1", "uniprot_id": "CUA1_DROME", "mass": 13119.0, "length": 135, "protein_name": "Adult cuticle protein 1", "gene_name": "Acp1", "organism": "Fruit fly", "refseq_name": "adult cuticle protein 1", "refseq_ac": "NP_477115", "gene_names_uniprotkb": "Acp1; CG7216", "gene_names_refseq": "Acp1; CG7216-PA; CG7216; Dacp-1; Dmel\\CG7216; acp1", "protein_names_uniprotkb": "Adult cuticle protein 1; dACP-1", "protein_names_refseq": "Acp1-PA; CG7216-PA; adult cuticle protein 1", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG7216)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "10731132;12537569;12537572;7875368", "class_list": "", "function": "Component of the cuticle of the adult fruit fly. Could be involved in thickening of the hard adult cuticle., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9VLY2", "ec_number_list": "", "go_molecular_function": "GO:0008012 structural constituent of adult chitin-based cuticle", "go_cellular_component": "", "go_biological_process": "GO:0008365 adult chitin-based cuticle development", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q26416-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q27367-1", "uniprot_id": "CRQ_DROME", "mass": 56154.0, "length": 491, "protein_name": "Protein croquemort", "gene_name": "crq", "organism": "Fruit fly", "refseq_name": "croquemort, isoform C", "refseq_ac": "NP_001245823", "gene_names_uniprotkb": "crq; CG4280", "gene_names_refseq": "CD36; CG31655; CG4280; CRQ; Cd36; Cqr; Croquemort; Crq; D-CD36; Dmel\\CG4280; anon-WO0140519.8; cqm; cqr; crq", "protein_names_uniprotkb": "Protein croquemort; d-CD36", "protein_names_refseq": "CD36-like; CG4280-PC; croquemort, isoform C; croquemort; crq-PC", "tax_id": 7227, "disease": "metabolic dysfunction and alcohol associated liver disease (Disease Ontology:DOID:0070508); morbid obesity (Disease Ontology:DOID:11981); end stage renal disease (Disease Ontology:DOID:783)", "pathway": " (dme:Dmel_CG4280); (R-DME-114608); (R-DME-1236973); (R-DME-434313); (R-DME-6798695)", "pathway_count": 5, "publication_count": 6, "publication_id_list": "10731132;12537572;17893096;21948708;34860835;8630729", "class_list": "", "function": "Macrophage receptor for apoptotic cells (PubMed:8630729). Up-regulates Bfc, which in turn leads to self-up-regulation by Bfc in a positive feedback mechanism in response to detection of apoptotic cells (PubMed:34860835)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 7, "predicted_n_glycosites": 7, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 2, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 2, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 2, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 9, "binding_glycan_count": 0, "secondary_ac_list": "A4UZX7;Q8SZG1;Q9VPQ1", "ec_number_list": "", "go_molecular_function": "GO:0005044 scavenger receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane", "go_biological_process": "GO:0090382 phagosome maturation;GO:0006909 phagocytosis;GO:0006915 apoptotic process;GO:0006910 phagocytosis, recognition;GO:0043277 apoptotic cell clearance", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q27367-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q27589-1", "uniprot_id": "CP4D2_DROME", "mass": 57917.0, "length": 501, "protein_name": "Cytochrome P450 4d2", "gene_name": "Cyp4d2", "organism": "Fruit fly", "refseq_name": "cytochrome P450 4d2, isoform B", "refseq_ac": "NP_001284806", "gene_names_uniprotkb": "Cyp4d2; CG3466", "gene_names_refseq": "4d2; CG3466; CYP4D2; Cyp4D2; Cyp4d2; Cyt-P450-4D2; Dmel\\CG3466; EG:152A3.4; P-450; P450", "protein_names_uniprotkb": "Cytochrome P450 4d2; 1.14.-.-; CYPIVD2", "protein_names_refseq": "CG3466-PB; Cyp4d2-PB; cytochrome P-450; cytochrome P450 4D2; cytochrome P450 4d2, isoform B; cytochrome P450-4d2", "tax_id": 7227, "disease": "Bietti crystalline corneoretinal dystrophy (Disease Ontology:DOID:0050664); hypertension (Disease Ontology:DOID:10763); polycystic ovary syndrome (Disease Ontology:DOID:11612); protein-energy malnutrition (Disease Ontology:DOID:11801); hypothyroidism (Disease Ontology:DOID:1459); endometriosis (Disease Ontology:DOID:289); placental insufficiency (Disease Ontology:DOID:3891)", "pathway": " (dme:Dmel_CG3466); (R-DME-193144); (R-DME-196791); (R-DME-211916); (R-DME-211976)", "pathway_count": 5, "publication_count": 5, "publication_id_list": "10731132;10731137;12537569;12537572;8024706", "class_list": "", "function": "Involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 7, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "O18651;O18674;O46053;Q27588;Q9W514;X2JI29", "ec_number_list": "1.14.-.-;1.14.15.-", "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0004497 monooxygenase activity;GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q27589-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q27593-1", "uniprot_id": "CP6A8_DROME", "mass": 58117.0, "length": 506, "protein_name": "Cytochrome P450 6a8", "gene_name": "Cyp6a8", "organism": "Fruit fly", "refseq_name": "cytochrome P450 6a8", "refseq_ac": "NP_523749", "gene_names_uniprotkb": "Cyp6a8; CG10248", "gene_names_refseq": "6a8; CG10248; CYP6A8; CYP6a8; Cyp6A8; Cyp6a8; Cyt-P450-rAF5; Dmel\\CG10248; P-450; P450; cyp6a8; lau", "protein_names_uniprotkb": "Cytochrome P450 6a8; 1.14.-.-; CYPVIA8", "protein_names_refseq": "CG10248-PA; Cyp6a8-PA; cytochrome P450 6a8; cytochrome P450 related AF5; cytochrome P450-6a8", "tax_id": 7227, "disease": "alcohol dependence (Disease Ontology:DOID:0050741); alcohol-associated liver disease (Disease Ontology:DOID:0070658); B-lymphoblastic leukemia/lymphoma (Disease Ontology:DOID:0080630); prostate cancer (Disease Ontology:DOID:10283); Alzheimer's disease (Disease Ontology:DOID:10652); essential hypertension (Disease Ontology:DOID:10825); cholestasis (Disease Ontology:DOID:13580); depressive disorder (Disease Ontology:DOID:1596); anxiety disorder (Disease Ontology:DOID:2030); familial Mediterranean fever (Disease Ontology:DOID:2987); liver cirrhosis (Disease Ontology:DOID:5082); oral submucous fibrosis (Disease Ontology:DOID:5773); end stage renal disease (Disease Ontology:DOID:783); chronic myeloid leukemia (Disease Ontology:DOID:8552); acute lymphoblastic leukemia (Disease Ontology:DOID:9952)", "pathway": " (dme:Dmel_CG10248)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "10731132;12537572;8973362", "class_list": "", "function": "Involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 15, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9V775", "ec_number_list": "", "go_molecular_function": "GO:0005504 fatty acid binding;GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0018685 alkane 1-monooxygenase activity;GO:0120503 medium-chain fatty acid omega-1 hydroxylase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane;GO:0012505 endomembrane system", "go_biological_process": "GO:0031000 response to caffeine;GO:0017143 insecticide metabolic process;GO:0048252 lauric acid metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q27593-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q27594-1", "uniprot_id": "CP6A9_DROME", "mass": 58005.0, "length": 504, "protein_name": "Cytochrome P450 6a9", "gene_name": "Cyp6a9", "organism": "Fruit fly", "refseq_name": "cytochrome P450 6a9", "refseq_ac": "NP_523748", "gene_names_uniprotkb": "Cyp6a9; CG10246", "gene_names_refseq": "6a9; CG10246; CYP6A9; CYP6a9; Cyp6A9; Cyp6a9; Cyt-P450-rAF4; Dmel\\CG10246; P-450; P450", "protein_names_uniprotkb": "Cytochrome P450 6a9; 1.14.-.-; CYPVIA9", "protein_names_refseq": "CG10246-PB; Cyp6a9-PB; cytochrome P450 6a9; cytochrome P450 related AF4; cytochrome P450-6a9", "tax_id": 7227, "disease": "alcohol dependence (Disease Ontology:DOID:0050741); alcohol-associated liver disease (Disease Ontology:DOID:0070658); B-lymphoblastic leukemia/lymphoma (Disease Ontology:DOID:0080630); prostate cancer (Disease Ontology:DOID:10283); Alzheimer's disease (Disease Ontology:DOID:10652); essential hypertension (Disease Ontology:DOID:10825); cholestasis (Disease Ontology:DOID:13580); depressive disorder (Disease Ontology:DOID:1596); anxiety disorder (Disease Ontology:DOID:2030); familial Mediterranean fever (Disease Ontology:DOID:2987); liver cirrhosis (Disease Ontology:DOID:5082); oral submucous fibrosis (Disease Ontology:DOID:5773); end stage renal disease (Disease Ontology:DOID:783); chronic myeloid leukemia (Disease Ontology:DOID:8552); acute lymphoblastic leukemia (Disease Ontology:DOID:9952)", "pathway": " (dme:Dmel_CG10246)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "10731132;12537569;12537572;8973362", "class_list": "", "function": "Involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 15, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q8MRY8;Q9V772", "ec_number_list": "", "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0004497 monooxygenase activity;GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q27594-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q4V4I9-1", "uniprot_id": "CCHA1_DROME", "mass": 20468.0, "length": 182, "protein_name": "Neuropeptide CCHamide-1", "gene_name": "CCHa1", "organism": "Fruit fly", "refseq_name": "CCHamide-1", "refseq_ac": "NP_001097784", "gene_names_uniprotkb": "CCHa1; CG14358", "gene_names_refseq": "CCH1; CCHA1; CCHa1; CCM; CCha1; CG14358; Dm-CCHa1; Dmel\\CG14358; ccha1", "protein_names_uniprotkb": "Neuropeptide CCHamide-1", "protein_names_refseq": "CCHa1-PB; CCHamide 1; CCHamide-1; CCHamide1; CG14358-PB; Drm-CCHamide-1", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG14358)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537572;21110953;21214272;23293632;24098432;24850274;26168160;30246807;36786215;36958331", "class_list": "", "function": "Neuropeptide ligand for the CCHamide-1 receptor CCHa1-R (PubMed:21110953, PubMed:23293632). Neuromessenger mediating signaling between neuronal cells of the circadian clock network involved in regulation of sleep latency (the time required to fall asleep), amount of sleep and depth of sleep (arousability) (PubMed:30246807, PubMed:36958331). Together with PDF, involved in regulating intensity and periodicity of daytime activity (PubMed:36786215). In subsets of clock neurons modulates the rhythmic expression of PDP1 and PDF, and together with PDF modulates the rhythmic expression of circadian protein PER/period, but not TIM/timeless (PubMed:30246807, PubMed:36786215). Mediates signaling from DN1a (anterior dorsal neurons 1) clock neurons to s-LNv (small ventral lateral neurons) clock neurons through CCHa1-R, contributing to regulation of activity rhythms by the circadian clock, particularly in the morning (PubMed:30246807). May be involved in signaling between clock neurons and non-clock neurons, such as the fan-shaped body, involved in sleep homeostasis (PubMed:36786215). In response to a high protein diet mediates hormonal signaling between the gut and a CCHa1-R expressing subset of dopaminergic cells in the protocerebral anterior medial (PAM) cluster of the brain (PubMed:36958331). This suppresses arousability by mechano-sensory stimulation (but not thermal stimulation) but is not involved in regulation of sleep patterns (PubMed:36958331)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A1L1VVC8;Q9VFN6", "ec_number_list": "", "go_molecular_function": "GO:0005184 neuropeptide hormone activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0007218 neuropeptide signaling pathway", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q4V4I9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q59DY5-1", "uniprot_id": "LEDL3_DROME", "mass": 17053.0, "length": 150, "protein_name": "C-type lectin 37Db", "gene_name": "lectin-37Db", "organism": "Fruit fly", "refseq_name": "lectin-37Db, isoform A", "refseq_ac": "NP_001014490", "gene_names_uniprotkb": "lectin-37Db; CG33533; DL3", "gene_names_refseq": "AC 007082C; AC007082c; CG33533; CG9978; DL3; Dmel\\CG33533; lectin-37Db", "protein_names_uniprotkb": "C-type lectin 37Db", "protein_names_refseq": "CG33533-PA; drosophila lectin 3; lectin-37Db, isoform A; lectin-37Db-PA", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG33533)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "10731132;12537572;16475980;17287021", "class_list": "", "function": "Galactose-specific lectin that displays calcium-dependent activity (PubMed:16475980, PubMed:17287021). Binds to the surface of hemocytes and enhances hemocyte encapsulation and melanization (PubMed:17287021). This is likely by interacting with carbohydrates on the surface of the hemocytes (PubMed:17287021). Also displays agglutination activity against the Gram-negative bacterium E.coli (PubMed:17287021)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "B3DNJ5;Q65Y00", "ec_number_list": "", "go_molecular_function": "GO:0046872 metal ion binding;GO:0030246 carbohydrate binding;GO:0038187 pattern recognition receptor activity;GO:0005534 galactose binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0009897 external side of plasma membrane", "go_biological_process": "GO:0006955 immune response;GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0035006 melanization defense response;GO:0035010 encapsulation of foreign target", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q59DY5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q5BI31-1", "uniprot_id": "ALMS1_DROME", "mass": 148123.0, "length": 1322, "protein_name": "Centrosome-associated protein Alms1a", "gene_name": "Alms1a", "organism": "Fruit fly", "refseq_name": "alstrom syndrome 1a, isoform C", "refseq_ac": "NP_572175", "gene_names_uniprotkb": "Alms1a; CG12179; EG:66A1.2", "gene_names_refseq": "Alms1a; CG12179; Dmel\\CG12179; EG:66A1.2; alms1a", "protein_names_uniprotkb": "Centrosome-associated protein Alms1a; Alstrom syndrome protein 1 homolog a", "protein_names_refseq": "Alms1a-PC; CG12179-PC; alstrom syndrome 1a, isoform C", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG12179)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "10731132;12537572;32965218", "class_list": "", "function": "In asymmetrically dividing germline stem cells (GSCs), plays a critical role in ensuring centrosome duplication, which is essential for the production of centrosomes and centrioles in all downstream germ cells (PubMed:32965218). Might recruit SAK for daughter centriole duplication (PubMed:32965218)., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q9W4I8;Q9W4I9", "ec_number_list": "", "go_molecular_function": "GO:0019900 kinase binding;GO:0019894 kinesin binding", "go_cellular_component": "GO:0005813 centrosome;GO:0005814 centriole", "go_biological_process": "GO:0046601 positive regulation of centriole replication;GO:0048133 male germ-line stem cell asymmetric division;GO:0010825 positive regulation of centrosome duplication", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q5BI31-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q5EAK6-1", "uniprot_id": "ATM_DROME", "mass": 317991.0, "length": 2767, "protein_name": "Serine/threonine-protein kinase ATM", "gene_name": "tefu", "organism": "Fruit fly", "refseq_name": "telomere fusion", "refseq_ac": "NP_001036712", "gene_names_uniprotkb": "tefu; CG6535; atm", "gene_names_refseq": "ATM; Atm; CG6535; Dmel\\CG6535; Tefu; atm/tefu; atm; dATM; tefu/atm; tefu; tef", "protein_names_uniprotkb": "Serine/threonine-protein kinase ATM; 2.7.11.1; Telomere fusion protein", "protein_names_refseq": "A-T mutated; CG6535-PB; ataxia telangectasia mutated; ataxia telangiectasia mutated; ataxia telengiesctasia mutated; ataxia-telangiectasia mutated; drosophila ATM; tefu-PB; telomere fusion", "tax_id": 7227, "disease": "female breast cancer (Disease Ontology:DOID:0050671); oral squamous cell carcinoma (Disease Ontology:DOID:0050866); lymphoma (Disease Ontology:DOID:0060058); pre-malignant neoplasm (Disease Ontology:DOID:0060071); stomach cancer (Disease Ontology:DOID:10534); Alzheimer's disease (Disease Ontology:DOID:10652); leukemia (Disease Ontology:DOID:1240); ataxia telangiectasia (Disease Ontology:DOID:12704); endometrial cancer (Disease Ontology:DOID:1380); Parkinson's disease (Disease Ontology:DOID:14330); disease of cellular proliferation (Disease Ontology:DOID:14566); breast cancer (Disease Ontology:DOID:1612); cancer (Disease Ontology:DOID:162); pancreatic cancer (Disease Ontology:DOID:1793); status epilepticus (Disease Ontology:DOID:1824); breast carcinoma (Disease Ontology:DOID:3459); esophagus squamous cell carcinoma (Disease Ontology:DOID:3748); lung squamous cell carcinoma (Disease Ontology:DOID:3907); lung non-small cell carcinoma (Disease Ontology:DOID:3908); papillary thyroid carcinoma (Disease Ontology:DOID:3969); infertility (Disease Ontology:DOID:5223); human immunodeficiency virus infectious disease (Disease Ontology:DOID:526); lung small cell carcinoma (Disease Ontology:DOID:5409); prostate carcinoma in situ (Disease Ontology:DOID:8634); colorectal cancer (Disease Ontology:DOID:9256); nasopharynx carcinoma (Disease Ontology:DOID:9261); oral mucosa leukoplakia (Disease Ontology:DOID:9655); senile cataract (Disease Ontology:DOID:9669)", "pathway": " (dme:Dmel_CG6535); (R-DME-2559586); (R-DME-5693548); (R-DME-5693565); (R-DME-5693607); (R-DME-6803204); (R-DME-6803207); (R-DME-6804756); (R-DME-69541); (R-DME-9664873)", "pathway_count": 10, "publication_count": 13, "publication_id_list": "10731132;12537569;12537572;14729967;15256487;15296750;15296751;15296752;16020777;16203987;19240120;22964637;40245499", "class_list": "", "function": "Serine/threonine-protein kinase which recognizes the substrate consensus sequence [ST]-Q. Required to suppress spontaneous apoptosis of proliferating cells during development, and for their proper differentiation. Required for female fertility. Protects telomeres from fusion, maybe by recruiting or maintaining chromatin-modifying complexes such as Su(var)205/HP1. May activate checkpoint signaling in response to DNA double-stranded breaks induced by low-dose ionizing radiation. May phosphorylate histone H2AV., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 4, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 4, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 4, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 28, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "Q0KI71;Q6TKQ1;Q8MZG4;Q9VFB1", "ec_number_list": "2.7.11.17;2.7.11.1;2.7.11.13;2.7.11.24;2.7.11.22;2.7.11.21;2.7.10.2;5.6.1.8;2.7.11.11;2.7.11.23;2.7.12.1;2.7.11.25;2.7.11.12;3.1.3.48;2.7.12.2;2.3.1.48;2.7.11.39;3.6.-.-;3.4.19.12", "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0035173 histone kinase activity;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005694 chromosome;GO:0000781 chromosome, telomeric region", "go_biological_process": "GO:0031509 subtelomeric heterochromatin formation;GO:0006281 DNA repair;GO:0043687 post-translational protein modification;GO:0000723 telomere maintenance;GO:0045494 photoreceptor cell maintenance", "synthesized_glycan_count": 0, "hit_score": 1.9, "record_id": "Q5EAK6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q5LJP9-1", "uniprot_id": "ASND1_DROME", "mass": 64746.0, "length": 564, "protein_name": "Asparagine synthetase domain-containing protein CG17486", "gene_name": "CG17486", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": "NP_001036446", "gene_names_uniprotkb": "CG17486", "gene_names_refseq": "CG17486; CG40291; Dmel\\CG17486", "protein_names_uniprotkb": "Asparagine synthetase domain-containing protein CG17486", "protein_names_refseq": "CG17486-PB; uncharacterized protein", "tax_id": 7227, "disease": "myopathy (Disease Ontology:DOID:423)", "pathway": " (dme:Dmel_CG17486)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "10731132;12537569;12537572", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9W5U0", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "GO:0070981 L-asparagine biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q5LJP9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q6WV17-1", "uniprot_id": "GALT5_DROME", "mass": 72097.0, "length": 630, "protein_name": "Polypeptide N-acetylgalactosaminyltransferase 5", "gene_name": "Pgant5", "organism": "Fruit fly", "refseq_name": "polypeptide N-Acetylgalactosaminyltransferase 5, isoform B", "refseq_ac": "NP_001036338", "gene_names_uniprotkb": "Pgant5; CG31651", "gene_names_refseq": "CG31651; CG9152; Dmel\\CG31651; PGANT5; Pgant5; l(2)e02157; pgant5; pgnat5", "protein_names_uniprotkb": "Polypeptide N-acetylgalactosaminyltransferase 5; 2.4.1.41; Protein-UDP acetylgalactosaminyltransferase 5; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 5; pp-GaNTase 5", "protein_names_refseq": "CG31651-PB; Pgant5-PB; lethal (2) e02157; polypeptide GalNAc transferase 5; polypeptide N-Acetylgalactosaminyltransferase 5, isoform B", "tax_id": 7227, "disease": "heart valve disease (Disease Ontology:DOID:4079)", "pathway": " (dme:Dmel_CG31651); (R-DME-6811436); (R-DME-913709)", "pathway_count": 3, "publication_count": 7, "publication_id_list": "10731132;12537569;12537572;12829714;16251381;18669915;22157008", "class_list": "", "function": "Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor (PubMed:12829714, PubMed:18669915). It can both act as a peptide transferase that transfers GalNAc onto unmodified peptide substrates, and as a glycopeptide transferase that requires the prior addition of a GalNAc on a peptide before adding additional GalNAc moieties. Prefers EA2 as substrate (PubMed:12829714). In the larval midgut, required for O-glycosylation of apical and luminal proteins within copper cells enabling proper gut acidification (PubMed:22157008)., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q0E8T2;Q95T43;Q9VMU3", "ec_number_list": "3.6.5.-;2.4.1.-;2.4.1.41", "go_molecular_function": "GO:0046872 metal ion binding;GO:0030246 carbohydrate binding;GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005794 Golgi apparatus;GO:0012505 endomembrane system;GO:0005795 Golgi stack", "go_biological_process": "GO:0006493 protein O-linked glycosylation;GO:0016266 protein O-linked glycosylation via N-acetyl-galactosamine", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q6WV17-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q709R6-1", "uniprot_id": "BOCKS_DROME", "mass": 44204.0, "length": 399, "protein_name": "LEM domain-containing protein Bocksbeutel", "gene_name": "bocks", "organism": "Fruit fly", "refseq_name": "bocksbeutel, isoform B", "refseq_ac": "NP_001014611", "gene_names_uniprotkb": "bocks; CG9424", "gene_names_refseq": "Bocksbeutel; Bocks; CG9424; Dmel\\CG9424; bocks; emerin", "protein_names_uniprotkb": "LEM domain-containing protein Bocksbeutel", "protein_names_refseq": "CG9424-PB; bocks-PB; bocksbeutel, isoform B; bocksbeutel", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG9424)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "10731132;12537572;15035436;16439308;18723885;24700158;40245499", "class_list": "", "function": "Inner nuclear membrane protein (PubMed:15035436, PubMed:24700158). May have a role in maintaining the structural integrity of the nuclear lamina (PubMed:24700158). During pupal development, plays essential and redundant functions with the other LEM domain proteins; MAN1 and Ote (PubMed:24700158). Also has a redundant but important role with Ote in larval development (PubMed:24700158)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q8SZZ5;Q9VHA7", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005635 nuclear envelope;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005783 endoplasmic reticulum;GO:0016020 membrane", "go_biological_process": "GO:0051301 cell division", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "Q709R6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q7JQ32-1", "uniprot_id": "GC76C_DROME", "mass": 170503.0, "length": 1525, "protein_name": "Receptor-type guanylate cyclase Gyc76C", "gene_name": "Gyc76C", "organism": "Fruit fly", "refseq_name": "guanylyl cyclase at 76C, isoform A", "refseq_ac": "NP_001163473", "gene_names_uniprotkb": "Gyc76C; CG42636", "gene_names_refseq": "CG32215; CG42636; CG8742; DGC1; Dmel\\CG42636; DrGC-1; GYC 76C; Gyc76C; drgc; gim; gyc76C; l(3)76BDl; l(3)L0090", "protein_names_uniprotkb": "Receptor-type guanylate cyclase Gyc76C; 4.6.1.2; DrGC-1", "protein_names_refseq": "CG42636-PA; Gyc76C-PA; gimli; guanylyl cyclase at 76C, isoform A; l(3)76BDl; lethal (3) L0090; receptor-type guanylate cyclase", "tax_id": 7227, "disease": "abdominal obesity-metabolic syndrome (Disease Ontology:DOID:0060611); congenital diarrhea 6 (Disease Ontology:DOID:0060780); obesity (Disease Ontology:DOID:9970)", "pathway": " (dme:Dmel_CG42636); (dme:Dmel_CG42637)", "pathway_count": 2, "publication_count": 10, "publication_id_list": "10731132;12537572;15282266;21893139;23213443;23862019;24284209;26440503;7706258;7759483", "class_list": "", "function": "Guanylate cyclase involved in the production of the second messenger cGMP (PubMed:24284209). Acts as a receptor for the NPLP1-4 peptide and modulates the innate immune IMD pathway in response to salt stress by inducing nuclear translocation of NF-kappa-B protein Rel which leads to increased expression of the antimicrobial peptide diptericin (PubMed:21893139). Plays a role in Sema-1a-mediated axon repulsion which is required for the correct establishment of neuromuscular connectivity (PubMed:15282266, PubMed:24284209). Required in developing embryonic somatic muscle for correct patterning of ventral and lateral muscles and for localization of integrin beta-ps at developing dorsal muscle myotendinous junctions (PubMed:23213443). Required for invagination, migration and lumen shape of the embryonic salivary gland by regulating the localization of the integrin-binding protein rhea/Talin to the visceral mesoderm surrounding the gland and maintaining the laminin matrix (PubMed:23862019). Required in the developing wing to regulate extracellular matrix (ECM) organization by activating the cGMP-dependent protein kinase For which represses the activity of matrix metalloproteases such as Mmp2 and decreases ECM matrix reorganization (PubMed:26440503)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 9, "predicted_n_glycosites": 9, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 9, "binding_glycan_count": 0, "secondary_ac_list": "Q24051", "ec_number_list": "4.6.1.2", "go_molecular_function": "GO:0004383 guanylate cyclase activity;GO:0005524 ATP binding;GO:0005525 GTP binding;GO:0030215 semaphorin receptor binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0006182 cGMP biosynthetic process;GO:0016199 axon midline choice point recognition;GO:0030198 extracellular matrix organization;GO:0035556 intracellular signal transduction;GO:0050830 defense response to Gram-positive bacterium", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "Q7JQ32-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q7JQW6-1", "uniprot_id": "LIAS_DROME", "mass": 42734.0, "length": 377, "protein_name": "Lipoyl synthase, mitochondrial", "gene_name": "Las", "organism": "Fruit fly", "refseq_name": "lipoic acid synthase", "refseq_ac": "NP_524183", "gene_names_uniprotkb": "Las; CG5231", "gene_names_refseq": "CG5231; Dmel\\CG5231; Las", "protein_names_uniprotkb": "Lipoyl synthase, mitochondrial; 2.8.1.8; LS; Lip-syn; Lipoate synthase; Lipoic acid synthase", "protein_names_refseq": "CG5231-PC; Las-PC; lipoic acid synthase", "tax_id": 7227, "disease": "pyruvate decarboxylase deficiency (Disease Ontology:DOID:3649)", "pathway": " (dme:Dmel_CG5231); (R-DME-9857492)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "10731132;12537569;12537572", "class_list": "", "function": "Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9VPF7", "ec_number_list": "2.8.1.8", "go_molecular_function": "GO:0046872 metal ion binding;GO:0051539 4 iron, 4 sulfur cluster binding;GO:0016992 lipoate synthase activity", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0009249 protein lipoylation;GO:0009107 lipoate biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q7JQW6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q7JRJ1-1", "uniprot_id": "EAF_DROME", "mass": 54928.0, "length": 504, "protein_name": "Ell-associated factor Eaf", "gene_name": "Eaf", "organism": "Fruit fly", "refseq_name": "ELL-associated factor, isoform D", "refseq_ac": "NP_610273", "gene_names_uniprotkb": "Eaf; CG11166", "gene_names_refseq": "CG11166; CG1706; Dmel\\CG11166; EP(2)2475; Eaf; LD35207; dEaf", "protein_names_uniprotkb": "Ell-associated factor Eaf; dEaf", "protein_names_refseq": "CG11166-PD; ELL-associated factor, isoform D; Eaf-PD; dELL-associated factor", "tax_id": 7227, "disease": "prostate cancer (Disease Ontology:DOID:10283); cancer (Disease Ontology:DOID:162)", "pathway": " (dme:Dmel_CG11166); (R-DME-112382); (R-DME-674695); (R-DME-75955)", "pathway_count": 4, "publication_count": 7, "publication_id_list": "10731132;12537569;12537572;18327897;18562276;22195968;40245499", "class_list": "", "function": "Promotes transcriptional elongation by Su(Tpl)/ELL. Essential for development., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 2, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "E1JGZ1;Q86PA3", "ec_number_list": "", "go_molecular_function": "GO:0003711 transcription elongation factor activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0008023 transcription elongation factor complex;GO:0032783 super elongation complex", "go_biological_process": "GO:0034243 regulation of transcription elongation by RNA polymerase II;GO:1905382 positive regulation of snRNA transcription by RNA polymerase II;GO:0034605 cellular response to heat;GO:0045893 positive regulation of DNA-templated transcription;GO:0006368 transcription elongation by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "Q7JRJ1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q7JUN3-1", "uniprot_id": "ABCD1_DROME", "mass": 82639.0, "length": 730, "protein_name": "ATP-binding cassette sub-family D member 1", "gene_name": "Abcd1", "organism": "Fruit fly", "refseq_name": "ATP binding cassette subfamily D member 1, isoform H", "refseq_ac": "NP_001245409", "gene_names_uniprotkb": "Abcd1; ABCD; CG2316", "gene_names_refseq": "ABCD1/2; ABCD; Abcd1; CG2316; DmCG2316; Dmel\\CG2316; dABCD", "protein_names_uniprotkb": "ATP-binding cassette sub-family D member 1; 7.6.2.4", "protein_names_refseq": "ATP binding cassette subfamily D member 1, isoform H; ATP binding cassette subfamily D; ATP-binding cassette, subfamily D, member 1; Abcd1-PH; CG2316-PH", "tax_id": 7227, "disease": "adrenoleukodystrophy (Disease Ontology:DOID:10588)", "pathway": " (dme:Dmel_CG2316); (R-DME-1369062); (R-DME-2046105); (R-DME-2046106); (R-DME-390247); (R-DME-9603798)", "pathway_count": 6, "publication_count": 3, "publication_id_list": "10731132;12537569;12537572", "class_list": "", "function": "Plays a role in the transport of free very-long-chain fatty acids (VLCFAs) as well as their CoA-esters across the peroxisomal membrane by acting as an ATP-specific binding subunit releasing ADP after ATP hydrolysis. Thus, plays a role in regulation of VLCFAs and energy metabolism namely, in the degradation and biosynthesis of fatty acids by beta-oxidation, mitochondrial function and microsomal fatty acid elongation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.2.1.-;1.2.1.3;1.-.-.-;7.6.2.4", "go_molecular_function": "GO:0005324 long-chain fatty acid transmembrane transporter activity;GO:0005524 ATP binding;GO:0042626 ATPase-coupled transmembrane transporter activity;GO:0016887 ATP hydrolysis activity;GO:0015607 ABC-type fatty-acyl-CoA transporter activity", "go_cellular_component": "GO:0005778 peroxisomal membrane", "go_biological_process": "GO:0001676 long-chain fatty acid metabolic process;GO:0006635 fatty acid beta-oxidation;GO:0042760 very long-chain fatty acid catabolic process;GO:0007031 peroxisome organization;GO:0015910 long-chain fatty acid import into peroxisome", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q7JUN3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q7JV70-1", "uniprot_id": "ARC2_DROME", "mass": 22622.0, "length": 193, "protein_name": "Activity-regulated cytoskeleton associated protein 2", "gene_name": "Arc2", "organism": "Fruit fly", "refseq_name": "Activity-regulated cytoskeleton associated protein 2", "refseq_ac": "NP_610956", "gene_names_uniprotkb": "Arc2; CG13941", "gene_names_refseq": "Arc2; BcDNA:SD11637; CG13941; Dmel\\CG13941; anon-WO0118547.456; dARC2; dArc2", "protein_names_uniprotkb": "Activity-regulated cytoskeleton associated protein 2; dArc2", "protein_names_refseq": "Activity-regulated cytoskeleton associated protein 2; Arc2-PA; CG13941-PA", "tax_id": 7227, "disease": "withdrawal disorder (Disease Ontology:DOID:0060001); anxiety disorder (Disease Ontology:DOID:2030); morphine dependence (Disease Ontology:DOID:2560); middle cerebral artery infarction (Disease Ontology:DOID:3525)", "pathway": " (dme:Dmel_CG13941)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "10731132;12537572;29328915", "class_list": "", "function": "Self-assembles into virion-like capsids that encapsulate RNAs and mediate intercellular RNA transfer. Arc2 protein is released from cells in extracellular vesicles that mediate the transfer of mRNA into neighboring cells., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding;GO:0042802 identical protein binding;GO:0005198 structural molecule activity", "go_cellular_component": "GO:1903561 extracellular vesicle;GO:0170047 virus-like capsid", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q7JV70-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q7JVA5-1", "uniprot_id": "CEP89_DROME", "mass": 54448.0, "length": 476, "protein_name": "Protein Cep89 homolog", "gene_name": "Cep89", "organism": "Fruit fly", "refseq_name": "centrosomal protein 89kDa", "refseq_ac": "NP_611053", "gene_names_uniprotkb": "Cep89; CG8214", "gene_names_refseq": "CEP89; CG8214; Cep89; Dmel\\CG8214; cep89", "protein_names_uniprotkb": "Protein Cep89 homolog", "protein_names_refseq": "CG8214-PA; Cep89-PA; centrosomal protein 89kDa homolog; centrosomal protein 89kDa", "tax_id": 7227, "disease": "neurodegenerative disease (Disease Ontology:DOID:1289); cytochrome-c oxidase deficiency disease (Disease Ontology:DOID:3762)", "pathway": " (dme:Dmel_CG8214)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "10731132;12537569;12537572;23575228", "class_list": "", "function": "Required for mitochondrial complex IV activity. May be involved in non-associative learning., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005758 mitochondrial intermembrane space;GO:0005829 cytosol;GO:0045202 synapse;GO:0005814 centriole;GO:0097539 ciliary transition fiber", "go_biological_process": "GO:0007268 chemical synaptic transmission;GO:0060271 cilium assembly;GO:0007005 mitochondrion organization;GO:1905515 non-motile cilium assembly;GO:0033617 mitochondrial respiratory chain complex IV assembly", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q7JVA5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q7JWD3-1", "uniprot_id": "ASNA_DROME", "mass": 37581.0, "length": 336, "protein_name": "ATPase ASNA1 homolog", "gene_name": "CG1598", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": "NP_610296", "gene_names_uniprotkb": "CG1598", "gene_names_refseq": "BEST:GH10483; BcDNA:GM18141; CG1598; Dmel\\CG1598; gh10483", "protein_names_uniprotkb": "ATPase ASNA1 homolog; 3.6.-.-; Arsenical pump-driving ATPase homolog; Arsenite-stimulated ATPase", "protein_names_refseq": "CG1598-PA; uncharacterized protein", "tax_id": 7227, "disease": "dilated cardiomyopathy (Disease Ontology:DOID:12930); cancer (Disease Ontology:DOID:162)", "pathway": " (dme:Dmel_CG1598)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "10731132;12537569;12537572", "class_list": "", "function": "ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the membrane-bound receptor, and returning it to the cytosol to initiate a new round of targeting., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q8SZC0", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0016887 ATP hydrolysis activity", "go_cellular_component": "GO:0043529 GET complex", "go_biological_process": "GO:0071816 tail-anchored membrane protein insertion into ER membrane", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q7JWD3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q7JWP6-1", "uniprot_id": "HPHP_DROME", "mass": 24357.0, "length": 221, "protein_name": "HP1-HOAP-interacting protein", "gene_name": "HipHop", "organism": "Fruit fly", "refseq_name": "HP1-HOAP-interacting protein, isoform A", "refseq_ac": "NP_649061", "gene_names_uniprotkb": "HipHop; CG6874", "gene_names_refseq": "BcDNA:RE10558; CG6874; Dmel\\CG6874; HIPHOP; HipHop; Hiphop; hiphop; l(3)neo26", "protein_names_uniprotkb": "HP1-HOAP-interacting protein", "protein_names_refseq": "CG6874-PA; HP1 and HOAP-interacting protein; HP1-HOAP interacting protein; HP1-HOAP-interacting protein, isoform A; HipHop-PA; hiphop; l(3)neo26; lethal (3) neo26", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG6874)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "10731132;12537569;12537572;16951084;19126864;20057353;27835648", "class_list": "", "function": "Part of the HipHop-HOAP complex that recruits the MTV complex to form the terminin telomere-capping complex, which binds to chromosome ends in a sequence-independent manner and prevents telomere fusion., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0000781 chromosome, telomeric region", "go_biological_process": "GO:0016233 telomere capping;GO:0031848 protection from non-homologous end joining at telomere;GO:0034080 CENP-A containing chromatin assembly", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q7JWP6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q7JWW5-1", "uniprot_id": "CTU1_DROME", "mass": 38521.0, "length": 343, "protein_name": "Cytoplasmic tRNA 2-thiolation protein 1", "gene_name": "Ctu1", "organism": "Fruit fly", "refseq_name": "cytosolic thiouridylase subunit 1", "refseq_ac": "NP_610451", "gene_names_uniprotkb": "Ctu1; CG8078", "gene_names_refseq": "CG8078; Ctu1; Dmel\\CG8078; anon-WO0118547.76", "protein_names_uniprotkb": "Cytoplasmic tRNA 2-thiolation protein 1; 2.7.7.-; Cytoplasmic tRNA adenylyltransferase 1", "protein_names_refseq": "CG8078-PA; Ctu1-PA; cytosolic thiouridylase subunit 1", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG8078)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "10731132;12537569;12537572;36302967", "class_list": "", "function": "Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0016783 sulfurtransferase activity;GO:0000049 tRNA binding;GO:0016779 nucleotidyltransferase activity", "go_cellular_component": "GO:0005829 cytosol;GO:0002144 cytosolic tRNA wobble base thiouridylase complex", "go_biological_process": "GO:0002143 tRNA wobble position uridine thiolation;GO:0034227 tRNA thio-modification;GO:0002098 tRNA wobble uridine modification;GO:0032447 protein urmylation", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q7JWW5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q7JX57-1", "uniprot_id": "EMRE_DROME", "mass": 10842.0, "length": 97, "protein_name": "Essential MCU regulator, mitochondrial", "gene_name": "EMRE", "organism": "Fruit fly", "refseq_name": "essential MCU regulator", "refseq_ac": "NP_611294", "gene_names_uniprotkb": "EMRE; CG17680", "gene_names_refseq": "BcDNA:RE55001; CG17680; Dmel\\CG17680; EMRE", "protein_names_uniprotkb": "Essential MCU regulator, mitochondrial", "protein_names_refseq": "CG17680-PA; EMRE-PA; essential MCU regulator", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG17680); (R-DME-8949215); (R-DME-8949664); (R-DME-9837999)", "pathway_count": 4, "publication_count": 5, "publication_id_list": "10731132;12537569;12537572;27099988;28726639", "class_list": "", "function": "Essential regulatory subunit of the mitochondrial calcium uniporter MCU channel, a protein that mediates calcium uptake into mitochondria., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005262 calcium channel activity", "go_cellular_component": "GO:0005743 mitochondrial inner membrane;GO:1990246 uniplex complex", "go_biological_process": "GO:0050829 defense response to Gram-negative bacterium;GO:0006851 mitochondrial calcium ion transmembrane transport;GO:0036444 calcium import into the mitochondrion;GO:0051560 mitochondrial calcium ion homeostasis;GO:0045089 positive regulation of innate immune response", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q7JX57-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q7K0F0-1", "uniprot_id": "CC130_DROME", "mass": 36340.0, "length": 316, "protein_name": "Coiled-coil domain-containing protein 130 homolog", "gene_name": "CG15084", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": "NP_611383", "gene_names_uniprotkb": "CG15084", "gene_names_refseq": "CG15084; Dmel\\CG15084", "protein_names_uniprotkb": "Coiled-coil domain-containing protein 130 homolog", "protein_names_refseq": "CG15084-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG15084)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "10731132;12537569;12537572", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0071014 post-mRNA release spliceosomal complex;GO:0005684 U2-type spliceosomal complex", "go_biological_process": "GO:0045292 mRNA cis splicing, via spliceosome", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q7K0F0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q7K175-1", "uniprot_id": "HENMT_DROME", "mass": 45570.0, "length": 391, "protein_name": "Small RNA 2'-O-methyltransferase", "gene_name": "Hen1", "organism": "Fruit fly", "refseq_name": "Hen1 methyltransferase", "refseq_ac": "NP_610732", "gene_names_uniprotkb": "Hen1; CG12367; Pimet", "gene_names_refseq": "CG12367; DmHen1; Dmel\\CG12367; FBgn 33686; Hen-1; Hen1; PIMET; Pimet/DmHen1; Pimet; hen-1; hen1", "protein_names_uniprotkb": "Small RNA 2'-O-methyltransferase; 2.1.1.386; DmHen1; HEN1 methyltransferase homolog; piRNA methyltransferase", "protein_names_refseq": "CG12367-PA; Hen1 methyltransferase; Hen1-PA; piRNA methyltransferase", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG12367)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "10731132;12537569;12537572;17604629;17606638;18463630;20558712", "class_list": "", "function": "Methyltransferase that adds a 2'-O-methyl group at the 3'-end of selected small RNAs. Mediates 2'-O-methylation of piRNAs, single-stranded siRNAs and long hairpin RNA genes (hpRNAs). Methylation protects the 3'-end of small RNAs from tailing and trimming and could constitute a recognition signal for appropriate argonaute machineries., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.1.1.386", "go_molecular_function": "GO:0090486 small RNA 2'-O-methyltransferase activity;GO:0003723 RNA binding;GO:0046872 metal ion binding;GO:0008171 O-methyltransferase activity;GO:0008173 RNA methyltransferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0030422 siRNA processing;GO:0034587 piRNA processing;GO:0001510 RNA methylation;GO:0010526 transposable element silencing;GO:0140990 primary piRNA processing", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q7K175-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q7K1U0-1", "uniprot_id": "ARC1_DROME", "mass": 28877.0, "length": 254, "protein_name": "Activity-regulated cytoskeleton associated protein 1", "gene_name": "Arc1", "organism": "Fruit fly", "refseq_name": "Activity-regulated cytoskeleton associated protein 1", "refseq_ac": "NP_610955", "gene_names_uniprotkb": "Arc1; CG12505", "gene_names_refseq": "Arc1; Arc; CG12505; Dmel\\CG12505; anon-WO0153538.31; anon-WO0153538.40; anon-WO0153538.41; anon-WO0153538.43; anon-WO0153538.45; arc1; dARC1; dArc1; darc1", "protein_names_uniprotkb": "Activity-regulated cytoskeleton associated protein 1; dArc1", "protein_names_refseq": "Activity-regulated cytoskeleton associated protein 1; Arc1-PA; CG12505-PA; dArc1", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG12505)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "10731132;12537569;12537572;26209258;29328915;29328916", "class_list": "", "function": "Master regulator of synaptic plasticity that self-assembles into virion-like capsids that encapsulate RNAs and mediate intercellular RNA transfer from motorneurons to muscles (PubMed:29328915). Arc1 protein is released from motorneurons in extracellular vesicles that mediate the transfer of Arc1 mRNA into muscle cells, where Arc1 mRNA can undergo activity-dependent translation (PubMed:29328915). Intercellular transfer od Arc1 mRNA is required for synaptic plasticity at the neuromuscular junction (PubMed:29328915). May play a role in energy balance: required for regulation of body fat by a specific population of brain neurons, named E347, that are necessary and sufficient for proper body fat storage (PubMed:26209258)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003729 mRNA binding;GO:0042802 identical protein binding;GO:0005198 structural molecule activity", "go_cellular_component": "GO:0045202 synapse;GO:0030017 sarcomere;GO:1903561 extracellular vesicle;GO:0098975 postsynapse of neuromuscular junction;GO:0170047 virus-like capsid", "go_biological_process": "GO:0042595 behavioral response to starvation;GO:0099156 cell-cell signaling via exosome;GO:0110077 vesicle-mediated intercellular transport;GO:0048168 regulation of neuronal synaptic plasticity;GO:0051028 mRNA transport", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q7K1U0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q7K1Y4-1", "uniprot_id": "CIAO1_DROME", "mass": 37044.0, "length": 335, "protein_name": "Probable cytosolic iron-sulfur protein assembly protein Ciao1", "gene_name": "Ciao1", "organism": "Fruit fly", "refseq_name": "Ciao1", "refseq_ac": "NP_610996", "gene_names_uniprotkb": "Ciao1; CG12797", "gene_names_refseq": "CG12797; CIAO1; CiaO1; Ciao1; Dmel\\CG12797", "protein_names_uniprotkb": "Probable cytosolic iron-sulfur protein assembly protein Ciao1", "protein_names_refseq": "CG12797-PA; Ciao1-PA; Ciao1", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG12797)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "10731132;12537569;12537572;28953965", "class_list": "", "function": "Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for the maturation of extramitochondrial Fe/S proteins., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0097361 cytosolic [4Fe-4S] assembly targeting complex;GO:0005829 cytosol", "go_biological_process": "GO:0016226 iron-sulfur cluster assembly;GO:0051604 protein maturation;GO:0044572 [4Fe-4S] cluster assembly", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q7K1Y4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q7K2D2-1", "uniprot_id": "DCTN2_DROME", "mass": 41998.0, "length": 380, "protein_name": "Dynactin subunit 2", "gene_name": "DCTN2-p50", "organism": "Fruit fly", "refseq_name": "dynactin 2, p50 subunit", "refseq_ac": "NP_524690", "gene_names_uniprotkb": "DCTN2-p50; CG8269; Dmn", "gene_names_refseq": "CG8269; DCTN2-p50; DCTN2; DMN; Dmel\\CG8269; Dmn; Dynamitin; P50; dDyn; dmn; dyna; l(2)k16109; l(2)k16218; p50/Dmn; p50/dynamitin; p50[Dmn]; p50", "protein_names_uniprotkb": "Dynactin subunit 2; Dynactin 2 p50 subunit; Dynamitin", "protein_names_refseq": "CG8269-PA; DCTN2-p50-PA; Dynactin2 p50; dynactin 2, p50 subunit; dynamitin; p50 dynamitin; p50-dynamitin; p50/Dynamitin", "tax_id": 7227, "disease": "synucleinopathy (Disease Ontology:DOID:0050890); retinal degeneration (Disease Ontology:DOID:8466)", "pathway": " (dme:Dmel_CG8269); (R-DME-3371497); (R-DME-6807878); (R-DME-6811436)", "pathway_count": 4, "publication_count": 4, "publication_id_list": "10731132;12537569;12537572;18327897", "class_list": "", "function": "Modulates cytoplasmic dynein binding to an organelle, and plays a role in prometaphase chromosome alignment and spindle organization during mitosis. May play a role in synapse formation during brain development (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005813 centrosome;GO:0005874 microtubule;GO:0005938 cell cortex;GO:0016020 membrane", "go_biological_process": "GO:0008090 retrograde axonal transport;GO:0007018 microtubule-based movement;GO:0007080 mitotic metaphase chromosome alignment;GO:0007602 phototransduction;GO:0007051 spindle organization", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q7K2D2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q7K3D8-1", "uniprot_id": "DMAP1_DROME", "mass": 50248.0, "length": 433, "protein_name": "DNA methyltransferase 1-associated protein 1", "gene_name": "DMAP1", "organism": "Fruit fly", "refseq_name": "DNA methyltransferase 1 associated protein 1", "refseq_ac": "NP_611503", "gene_names_uniprotkb": "DMAP1; CG11132", "gene_names_refseq": "CG11132; DMAP1; DMA; Dmel\\CG11132; Q7K3D8_DROME; dDMAP1", "protein_names_uniprotkb": "DNA methyltransferase 1-associated protein 1", "protein_names_refseq": "CG11132-PA; DMAP1-PA; DNA methyltransferase 1 associated protein 1", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG11132)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "10731132;12537569;12537572;15528408;24947515;32432549", "class_list": "", "function": "Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of histone H4 'Lys-12' (PubMed:32432549). Component of a SWR1-like complex that incorporates H2A.V genome-wide and specifically at active promoters, in an ATP-dependent manner (PubMed:32432549). Involved in transcription repression and activation (By similarity). Component of the Tip60 chromatin-remodeling complex that upon induction of DNA double-strand breaks, mediates the ATP-dependent exchange of unmodified histone H2AV for its phosphorylated and acetylated form H2AVK5acS138ph, leading to transcriptional regulation of selected genes by chromatin remodeling (PubMed:15528408). Required for larvae and pupal development, and for normal innate immune responses (PubMed:24947515). Involved in modulating the activation of the immune deficiency pathway (Imd), acting either downstream of, or at the level of, the NF-kappa-B factor Rel (PubMed:24947515). Possibly functions with akirin to regulate Rel, and its interaction with the Brahma complex protein Bap55 suggests that it may regulate the IMD pathway at the level of chromatin remodeling (PubMed:24947515)., [UniProtKB, UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003714 transcription corepressor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0035267 NuA4 histone acetyltransferase complex;GO:0000812 Swr1 complex", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006281 DNA repair;GO:0006338 chromatin remodeling;GO:0006351 DNA-templated transcription;GO:0045893 positive regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q7K3D8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q7K486-1", "uniprot_id": "ARMC6_DROME", "mass": 51378.0, "length": 464, "protein_name": "Armadillo repeat-containing protein 6 homolog", "gene_name": "CG5721", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": "NP_611306", "gene_names_uniprotkb": "CG5721", "gene_names_refseq": "CG5721; Dmel\\CG5721", "protein_names_uniprotkb": "Armadillo repeat-containing protein 6 homolog", "protein_names_refseq": "CG5721-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG5721)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "10731132;12537569;12537572;18327897", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "GO:0002244 hematopoietic progenitor cell differentiation;GO:0009653 anatomical structure morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q7K486-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q7K4B3-1", "uniprot_id": "ELP2_DROME", "mass": 88974.0, "length": 794, "protein_name": "Elongator complex protein 2", "gene_name": "Elp2", "organism": "Fruit fly", "refseq_name": "elongator complex protein 2", "refseq_ac": "NP_610600", "gene_names_uniprotkb": "Elp2; CG11887; StIP", "gene_names_refseq": "CG1187; CG11887; D-elp2; Dmel\\CG11887; Elp2; StIP; Stip; elp-2; elp2", "protein_names_uniprotkb": "Elongator complex protein 2; Stat3-interacting protein homolog", "protein_names_refseq": "CG11887-PA; Elp2-PA; StIP; elongator complex protein 2", "tax_id": 7227, "disease": "autism spectrum disorder (Disease Ontology:DOID:0060041); autosomal recessive intellectual developmental disorder 58 (Disease Ontology:DOID:0081220); intellectual disability (Disease Ontology:DOID:1059)", "pathway": " (dme:Dmel_CG11887)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "10731132;12537569;12537572;36302967", "class_list": "", "function": "Component of the elongator complex, which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine) (PubMed:36302967). The elongator complex catalyzes the formation of carboxymethyluridine in the wobble base at position 34 in tRNAs (PubMed:36302967). Binding by the elongator complex stabilizes microtubules and promotes their growth (PubMed:36302967). This induces central spindle asymmetry, promoting polarized signaling endosome trafficking during asymmetric cell division and cell fate assignation of sensory organ precursor cells (PubMed:36302967). Involved in the regulation of the STAT pathway (Ref.4)., [UniProtKB, UniProtKB, UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005819 spindle;GO:0005874 microtubule;GO:0033588 elongator holoenzyme complex", "go_biological_process": "GO:0006417 regulation of translation;GO:0002098 tRNA wobble uridine modification;GO:0061867 establishment of mitotic spindle asymmetry", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q7K4B3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q7K4B4-1", "uniprot_id": "DGT5_DROME", "mass": 77978.0, "length": 685, "protein_name": "Augmin complex subunit dgt5", "gene_name": "dgt5", "organism": "Fruit fly", "refseq_name": "dim gamma-tubulin 5, isoform B", "refseq_ac": "NP_001286349", "gene_names_uniprotkb": "dgt5; CG8828", "gene_names_refseq": "CG8828; Dgt5; Dmel\\CG8828; dgt5; msd2", "protein_names_uniprotkb": "Augmin complex subunit dgt5; Dim gamma-tubulin 5", "protein_names_refseq": "CG8828-PB; dgt5-PB; dim gamma-tubulin 5, isoform B; mitotic spindle density 2", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG8828)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "10731132;12537569;12537572;17412918;18443220;19369198;24829288", "class_list": "", "function": "As part of the augmin complex, plays a role in centrosome-independent generation of spindle microtubules (PubMed:18443220). The complex is required for mitotic spindle assembly through its involvement in localizing gamma-tubulin to spindle microtubules (PubMed:17412918)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0030674 protein-macromolecule adaptor activity", "go_cellular_component": "GO:0005813 centrosome;GO:0005819 spindle;GO:0005874 microtubule;GO:0000776 kinetochore;GO:0070652 HAUS complex", "go_biological_process": "GO:0010968 regulation of microtubule nucleation;GO:0051301 cell division;GO:0090307 mitotic spindle assembly;GO:0007088 regulation of mitotic nuclear division;GO:0007098 centrosome cycle", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q7K4B4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q7K4V4-1", "uniprot_id": "AKTP1_DROME", "mass": 28133.0, "length": 244, "protein_name": "Protein pendolino", "gene_name": "peo", "organism": "Fruit fly", "refseq_name": "pendolino, isoform B", "refseq_ac": "NP_524888", "gene_names_uniprotkb": "peo; CG10536; CG46338; cbx", "gene_names_refseq": "CG10536; CG46338; Dmel\\CG46338; Ft1; cbx; pen; peo", "protein_names_uniprotkb": "Protein pendolino", "protein_names_refseq": "CG46338-PB; pendolino, isoform B; pendolino; peo-PB", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG46338)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "10731132;12537569;12537572;26110638;26786804", "class_list": "", "function": "Required for efficient DNA replication, probably through involvement in telomere replication (PubMed:26110638). May have a role in telomere capping of heterochromatic chromosome ends (PubMed:26110638)., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A0B4KF51;Q7JRK3", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005730 nucleolus;GO:0005694 chromosome", "go_biological_process": "GO:0006260 DNA replication;GO:0042742 defense response to bacterium;GO:0007291 sperm individualization", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q7K4V4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q7K4W1-1", "uniprot_id": "CDKAL_DROME", "mass": 62633.0, "length": 552, "protein_name": "Threonylcarbamoyladenosine tRNA methylthiotransferase", "gene_name": "CG6550", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": "NP_611207", "gene_names_uniprotkb": "CG6550", "gene_names_refseq": "CDKAL1-like; CG6550; Dmel\\CG6550", "protein_names_uniprotkb": "Threonylcarbamoyladenosine tRNA methylthiotransferase; 2.8.4.5; CDKAL1-like protein; tRNA-t(6)A37 methylthiotransferase", "protein_names_refseq": "CG6550-PA; uncharacterized protein", "tax_id": 7227, "disease": "gestational diabetes (Disease Ontology:DOID:11714); diabetic retinopathy (Disease Ontology:DOID:8947); diabetes mellitus (Disease Ontology:DOID:9351); type 2 diabetes mellitus (Disease Ontology:DOID:9352)", "pathway": " (dme:Dmel_CG6550)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "10731132;12537569;12537572", "class_list": "", "function": "Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.8.4.5", "go_molecular_function": "GO:0046872 metal ion binding;GO:0051539 4 iron, 4 sulfur cluster binding;GO:0035598 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0016020 membrane;GO:0012505 endomembrane system", "go_biological_process": "GO:0035600 tRNA methylthiolation", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q7K4W1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q7K566-1", "uniprot_id": "BMCP_DROME", "mass": 33493.0, "length": 303, "protein_name": "Mitochondrial uncoupling protein Bmcp", "gene_name": "Bmcp", "organism": "Fruit fly", "refseq_name": "bmcp, isoform B", "refseq_ac": "NP_648501", "gene_names_uniprotkb": "Bmcp; CG7314; Ucp5", "gene_names_refseq": "BMCP; Bmcp; CG7314; DmBMCP; DmUCP5; Dmel\\CG7314; UCP5; Ucp5; bmcp; dUCP5; dmUCP5; dmUcp5; ucp5", "protein_names_uniprotkb": "Mitochondrial uncoupling protein Bmcp; Bmcp-1; Brain mitochondrial carrier protein 1; Mitochondrial uncoupling protein 5", "protein_names_refseq": "Bmcp-PB; CG7314-PB; bmcp, isoform B", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG7314); (R-DME-167826)", "pathway_count": 2, "publication_count": 5, "publication_id_list": "10731132;12537569;12537572;15337852;16387864", "class_list": "", "function": "Regulates metabolic homeostasis in response to nutritional cues and may therefore be involved in adaptation to dietary variations. May not function in creating mitochondrial proton leaks across the inner mitochondrial membrane (i.e. mitochondrial uncoupling)., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0022857 transmembrane transporter activity", "go_cellular_component": "GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0007605 sensory perception of sound", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q7K566-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q7K5N4-1", "uniprot_id": "CALYP_DROME", "mass": 51507.0, "length": 471, "protein_name": "Ubiquitin carboxyl-terminal hydrolase calypso", "gene_name": "caly", "organism": "Fruit fly", "refseq_name": "calypso, isoform A", "refseq_ac": "NP_611096", "gene_names_uniprotkb": "caly; BAP1; CG8445", "gene_names_refseq": "BAP1; CG8445; Calypso; Dmel\\CG8445; Q7K5N4; bap1; caly", "protein_names_uniprotkb": "Ubiquitin carboxyl-terminal hydrolase calypso; 3.4.19.12; BAP1 homolog; BRCA1-associated protein 1 homolog; Polycomb group protein calypso", "protein_names_refseq": "CG8445-PA; caly-PA; calypso, isoform A; calypso; ubiquitin thiolesterase", "tax_id": 7227, "disease": "myelodysplastic syndrome (Disease Ontology:DOID:0050908); basal cell carcinoma (Disease Ontology:DOID:2513); extrahepatic bile duct adenocarcinoma (Disease Ontology:DOID:3495); intrahepatic cholangiocarcinoma (Disease Ontology:DOID:4928); uveal melanoma (Disease Ontology:DOID:6039); malignant pleural mesothelioma (Disease Ontology:DOID:7474)", "pathway": " (dme:Dmel_CG8445); (R-DME-5689603)", "pathway_count": 2, "publication_count": 8, "publication_id_list": "10731132;12537569;12537572;17717194;20436459;30258054;30639226;36180891", "class_list": "", "function": "Catalytic component of the polycomb repressive deubiquitinase (PR-DUB) complex, a complex that specifically mediates deubiquitination of histone H2A monoubiquitinated at 'Lys-119' (H2AK118ub1) (PubMed:20436459, PubMed:30258054, PubMed:30639226, PubMed:36180891). Mediates bisymmetric organization of the PR-DUB complex and is involved in association with nucleosomes to mediate deubiquitination (PubMed:30258054). Does not deubiquitinate monoubiquitinated histone H2B (PubMed:20436459). Required to maintain the transcriptionally repressive state of homeotic genes throughout development (PubMed:20436459). The PR-DUB complex has weak or no activity toward 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains (PubMed:20436459). Polycomb group (PcG) protein (PubMed:17717194)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 10, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 6, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.4.19.12", "go_molecular_function": "GO:0003682 chromatin binding;GO:0004843 cysteine-type deubiquitinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0000785 chromatin;GO:0035517 PR-DUB complex", "go_biological_process": "GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0006511 ubiquitin-dependent protein catabolic process;GO:0040029 epigenetic regulation of gene expression;GO:0031507 heterochromatin formation;GO:0007385 specification of segmental identity, abdomen", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q7K5N4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q7KM13-1", "uniprot_id": "HEY_DROME", "mass": 46815.0, "length": 425, "protein_name": "Hairy/enhancer-of-split related with YRPW motif protein", "gene_name": "Hey", "organism": "Fruit fly", "refseq_name": "Hairy/E(spl)-related with YRPW motif", "refseq_ac": "NP_523657", "gene_names_uniprotkb": "Hey; CG11194; Hesr-1", "gene_names_refseq": "CG11194; Dmel\\CG11194; HEY; Hesr-1; Hey; bHLHe44; d-hey; dHey; hesr-1; hey", "protein_names_uniprotkb": "Hairy/enhancer-of-split related with YRPW motif protein", "protein_names_refseq": "CG11194-PA; Hairy/E(spl) related with YRPW motif; Hairy/E(spl)-related with YRPW motif; Hairy/E(spl)-related; Hey-PA; hairy and enhancer of split related protein; hairy and enhancer of split related-1", "tax_id": 7227, "disease": "hemangiopericytoma (Disease Ontology:DOID:264); hemangioblastoma (Disease Ontology:DOID:5241); aortic valve disease (Disease Ontology:DOID:62); tetralogy of Fallot (Disease Ontology:DOID:6419); varicose veins (Disease Ontology:DOID:799); diabetes mellitus (Disease Ontology:DOID:9351)", "pathway": " (dme:Dmel_CG11194)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "10403790;10731132;12537572", "class_list": "", "function": "Transcriptional repressor which acts as a downstream effector of Notch signaling., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 6, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q058S4", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0046983 protein dimerization activity;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0007219 Notch signaling pathway;GO:0009952 anterior/posterior pattern specification;GO:0050767 regulation of neurogenesis", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q7KM13-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q7KNA0-1", "uniprot_id": "DYM_DROME", "mass": 79125.0, "length": 699, "protein_name": "Dymeclin", "gene_name": "CG8230", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": "NP_610431", "gene_names_uniprotkb": "CG8230", "gene_names_refseq": "BcDNA:GH02536; CG8230; Dmel\\CG8230", "protein_names_uniprotkb": "Dymeclin", "protein_names_refseq": "CG8230-PA; uncharacterized protein", "tax_id": 7227, "disease": "Smith-McCort dysplasia (Disease Ontology:DOID:0060247); Smith-McCort dysplasia 1 (Disease Ontology:DOID:0081270); Dyggve-Melchior-Clausen disease (Disease Ontology:DOID:0111167); osteochondrodysplasia (Disease Ontology:DOID:2256)", "pathway": " (dme:Dmel_CG8230)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "10731132;10731138;12537572;17372656;18327897", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005794 Golgi apparatus", "go_biological_process": "GO:0007030 Golgi organization", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q7KNA0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q7KQM6-1", "uniprot_id": "GGYF1_DROME", "mass": 173730.0, "length": 1574, "protein_name": "GIGYF family protein Gyf", "gene_name": "Gyf", "organism": "Fruit fly", "refseq_name": "gigyf, isoform G", "refseq_ac": "NP_001162827", "gene_names_uniprotkb": "Gyf; CG11148", "gene_names_refseq": "CG11148; Dmel\\CG11148; GIGYF2; Gyf", "protein_names_uniprotkb": "GIGYF family protein Gyf; Gigyf", "protein_names_refseq": "CG11148-PG; Gyf-PG; gigyf, isoform G", "tax_id": 7227, "disease": "developmental disorder of mental health (Disease Ontology:DOID:0060037); Parkinson's disease (Disease Ontology:DOID:14330); schizophrenia (Disease Ontology:DOID:5419)", "pathway": " (dme:Dmel_CG11148)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "10731132;12537569;12537572;17372656;18327897;26086452;31114929;31439631;40245499", "class_list": "", "function": "Key component of the 4EHP-GYF2 complex, a multiprotein complex that acts as a repressor of translation initiation (PubMed:31114929). In the 4EHP-GYF2 complex, promotes translational repression and decay of mRNA targets by recruiting and bridging the association of the 4EHP complex with decapping effector proteins, such as me31B and Patr-1, and the deadenylation CCR4-NOT complex (PubMed:31114929). Involved in regulating starvation-induced, developmental and physiological autophagy, which is critical for eliminating ubiquitinated proteins and dysfunctional organelles in order to maintain tissue homeostasis (PubMed:26086452)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 3, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 3, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 3, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 8, "reported_mutagensis": 11, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 3, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "B8A422;D1YSG2;E8NH20;Q961G4;Q9V482", "ec_number_list": "", "go_molecular_function": "GO:0000900 mRNA regulatory element binding translation repressor activity", "go_cellular_component": "GO:0005829 cytosol;GO:0016281 eukaryotic translation initiation factor 4F complex", "go_biological_process": "GO:0010506 regulation of autophagy;GO:0046716 muscle cell cellular homeostasis;GO:0070050 neuron cellular homeostasis;GO:0045947 negative regulation of translational initiation", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "Q7KQM6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q7KTH8-1", "uniprot_id": "CSN8_DROME", "mass": 21431.0, "length": 182, "protein_name": "COP9 signalosome complex subunit 8", "gene_name": "CSN8", "organism": "Fruit fly", "refseq_name": "COP9 signalosome subunit 8", "refseq_ac": "NP_723378", "gene_names_uniprotkb": "CSN8; CG13383", "gene_names_refseq": "CG13383; CG33297; CG42522; CH8; CSN8; Csn8; Dch8; Dmel\\CG42522; csn8; l(2)SH1829; l(2)SH2 1829", "protein_names_uniprotkb": "COP9 signalosome complex subunit 8; Dch8; Signalosome subunit 8", "protein_names_refseq": "CG42522-PB; COP9 complex homolog subunit 8; COP9 signalosome subunit 8; CSN8-PB; drosophila COP9 signalosome homolog 8; lethal (2) SH1829", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG42522); (R-DME-5696394); (R-DME-6781823); (R-DME-8856825); (R-DME-8951664)", "pathway_count": 5, "publication_count": 5, "publication_id_list": "10531038;10731132;12537572;12737805;18298797", "class_list": "", "function": "Probable component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of the SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF. The CSN complex plays an essential role in oogenesis and embryogenesis and is required for proper photoreceptor R cell differentiation and promote lamina glial cell migration or axon targeting. It also promotes Ubl-dependent degradation of cyclin E (CycE) during early oogenesis., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q0E8L3", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0008180 COP9 signalosome", "go_biological_process": "GO:0050821 protein stabilization;GO:0042742 defense response to bacterium;GO:0042461 photoreceptor cell development;GO:0048477 oogenesis;GO:0010387 COP9 signalosome assembly", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q7KTH8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q7KW39-1", "uniprot_id": "MMSA_DROME", "mass": 55972.0, "length": 520, "protein_name": "Probable methylmalonate-semialdehyde/malonate-semialdehyde dehydrogenase [acylating], mitochondrial", "gene_name": "CG17896", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform B", "refseq_ac": "NP_569845", "gene_names_uniprotkb": "CG17896", "gene_names_refseq": "153323_at; CG17896; Dmel\\CG17896; EG:171D11.1", "protein_names_uniprotkb": "Probable methylmalonate-semialdehyde/malonate-semialdehyde dehydrogenase [acylating], mitochondrial; 1.2.1.27; MMSDH; Malonate-semialdehyde dehydrogenase [acylating]", "protein_names_refseq": "CG17896-PB; uncharacterized protein, isoform B", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG17896); (R-DME-70895)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "10731132;10731137;12537572", "class_list": "", "function": "Probable malonate and methylmalonate semialdehyde dehydrogenase involved in the catabolism of valine, thymine, and compounds catabolized by way of beta-alanine, including uracil and cytidine., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "O46056;Q8T9I0;Q9V408", "ec_number_list": "1.2.1.27", "go_molecular_function": "GO:0004491 methylmalonate-semialdehyde dehydrogenase (acylating, NAD) activity", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0006210 thymine catabolic process;GO:0006574 L-valine catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q7KW39-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q7PLI7-1", "uniprot_id": "DCLK_DROME", "mass": 82971.0, "length": 748, "protein_name": "Serine/threonine-protein kinase CG17528", "gene_name": "CG17528", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform D", "refseq_ac": "NP_001036462", "gene_names_uniprotkb": "CG17528", "gene_names_refseq": "CAMK-like; CG17528; CG40283; Dmel\\CG17528; PK1; Pk1; zyg8", "protein_names_uniprotkb": "Serine/threonine-protein kinase CG17528; 2.7.11.1; Doublecortin-like and CAM kinase-like protein; Protein Pk1", "protein_names_refseq": "CG17528-PD; protein kinase 1; uncharacterized protein, isoform D", "tax_id": 7227, "disease": "lissencephaly (Disease Ontology:DOID:0050453); subcortical band heterotopia (Disease Ontology:DOID:0111169); X-linked lissencephaly 1 (Disease Ontology:DOID:0112239); high grade glioma (Disease Ontology:DOID:3070); temporal lobe epilepsy (Disease Ontology:DOID:3328); dyslexia (Disease Ontology:DOID:4428)", "pathway": " (dme:Dmel_CG17528); (R-DME-111932); (R-DME-442729)", "pathway_count": 3, "publication_count": 5, "publication_id_list": "10731132;12537569;12537572;18327897;40245499", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 3, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 3, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 3, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 9, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 6, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "Q24057;Q7PLI6;Q8SWT6", "ec_number_list": "2.7.11.17;2.7.11.1;2.7.11.13;2.7.11.24;2.7.11.22;2.7.11.21;5.6.1.8;2.7.11.11;2.7.11.23;2.7.12.1;2.7.11.25;2.7.11.12;2.7.12.2;2.7.10.2;2.7.11.39", "go_molecular_function": "GO:0009931 calcium-dependent protein serine/threonine kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0005516 calmodulin binding;GO:0005524 ATP binding;GO:0004683 calcium/calmodulin-dependent protein kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0035556 intracellular signal transduction", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "Q7PLI7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q8IA43-1", "uniprot_id": "GLT10_DROME", "mass": 72795.0, "length": 630, "protein_name": "Putative polypeptide N-acetylgalactosaminyltransferase 10", "gene_name": "pgant10", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": "NP_722909", "gene_names_uniprotkb": "pgant10; CG31776", "gene_names_refseq": "CG31776; CG8845a; CG8845; Dmel\\CG31776; dppGalNAcT10", "protein_names_uniprotkb": "Putative polypeptide N-acetylgalactosaminyltransferase 10; 2.4.1.41; Protein-UDP acetylgalactosaminyltransferase 10; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 10; pp-GaNTase 10", "protein_names_refseq": "CG31776-PA; uncharacterized protein", "tax_id": 7227, "disease": "depressive disorder (Disease Ontology:DOID:1596)", "pathway": " (dme:Dmel_CG31776); (R-DME-913709)", "pathway_count": 2, "publication_count": 4, "publication_id_list": "10731132;11925450;12537572;16251381", "class_list": "", "function": "May catalyze the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor., [UniProtKB]", "predicted_glycosites": 5, "predicted_n_glycosites": 5, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "Q4V529;Q9VQR4", "ec_number_list": "2.4.1.-;2.4.1.41", "go_molecular_function": "GO:0046872 metal ion binding;GO:0030246 carbohydrate binding;GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005794 Golgi apparatus", "go_biological_process": "GO:0006493 protein O-linked glycosylation;GO:0016266 protein O-linked glycosylation via N-acetyl-galactosamine", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q8IA43-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q8IGJ0-2", "uniprot_id": "EFR3_DROME", "mass": 93961.0, "length": 834, "protein_name": "Protein EFR3 homolog cmp44E", "gene_name": "stmA", "organism": "Fruit fly", "refseq_name": "stambha A, isoform C", "refseq_ac": "NP_001014513", "gene_names_uniprotkb": "stmA; CG8739; cmp44E", "gene_names_refseq": "CG8739; Dmel\\CG8739; RBO; Rbo; StmA; cmp44E; rbo; stambhA; stm-A; stmA", "protein_names_uniprotkb": "Protein EFR3 homolog cmp44E; Conserved membrane protein at 44E; Protein stambha A", "protein_names_refseq": "CG8739-PC; conserved membrane protein at 44E; rolling blackout; stambh A; stambhA; stambha A, isoform C; stmA-PC", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG8739)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "10731132;12537569;12537572;9883579", "class_list": "", "function": "An essential gene required for embryogenesis; required for cell viability., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A1Z7I7;A1Z7I8;A1Z7I9;O96648;Q7K2E8", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane;GO:0045202 synapse;GO:0098793 presynapse", "go_biological_process": "GO:0072659 protein localization to plasma membrane;GO:0007268 chemical synaptic transmission;GO:0007602 phototransduction;GO:0016079 synaptic vesicle exocytosis;GO:0048488 synaptic vesicle endocytosis", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q8IGJ0-2", "record_type": "protein" }, { "uniprot_canonical_ac": "Q8IH18-1", "uniprot_id": "4ET_DROME", "mass": 113890.0, "length": 1010, "protein_name": "Eukaryotic translation initiation factor 4E transporter", "gene_name": "4E-T", "organism": "Fruit fly", "refseq_name": "eIF4E-Transporter, isoform H", "refseq_ac": "NP_001259078", "gene_names_uniprotkb": "4E-T; CG32016", "gene_names_refseq": "4E-T; CG11097; CG11232; CG32016; Dm4E-T; Dmel\\CG32016", "protein_names_uniprotkb": "Eukaryotic translation initiation factor 4E transporter; 4E-T; Dm4E-T; eIF4E transporter", "protein_names_refseq": "4E-T-PH; CG32016-PH; eIF4E-Transporter, isoform H", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG32016)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "10731132;12537572;24335285;25702871;31439631", "class_list": "", "function": "eIF4E1-binding protein that regulates translation and stability of mRNAs in processing bodies (P-bodies) (By similarity). Probably plays a role in P-bodies to coordinate the storage of translationally inactive mRNAs in the cytoplasm and prevent their degradation (By similarity). Acts as a binding platform for multiple RNA-binding proteins. Required for the formation of P-bodies (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "L0MLQ9;Q86BR2;Q8IMA1", "ec_number_list": "", "go_molecular_function": "GO:0003729 mRNA binding;GO:0008190 eukaryotic initiation factor 4E binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0000932 P-body", "go_biological_process": "GO:0017148 negative regulation of translation;GO:1905536 negative regulation of eukaryotic translation initiation factor 4F complex assembly", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q8IH18-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q8IMN5-1", "uniprot_id": "GR98D_DROME", "mass": 47723.0, "length": 412, "protein_name": "Putative gustatory receptor 98d", "gene_name": "Gr98d", "organism": "Fruit fly", "refseq_name": "gustatory receptor 98d", "refseq_ac": "NP_733214", "gene_names_uniprotkb": "Gr98d; CG31061; GR98B.1", "gene_names_refseq": "98B.1; CG12884; CG31061; Dmel\\CG31061; GR98B.1; GR98d; Gr98A1; Gr98B1; Gr98d", "protein_names_uniprotkb": "Putative gustatory receptor 98d", "protein_names_refseq": "CG31061-PA; Gr98d-PA; gustatory receptor 98B.1; gustatory receptor 98d", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG31061)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "10710312;10731132;12537572", "class_list": "", "function": "Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0015276 ligand-gated monoatomic ion channel activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane;GO:0030424 axon;GO:0030425 dendrite;GO:0043025 neuronal cell body", "go_biological_process": "GO:0007165 signal transduction;GO:0034220 monoatomic ion transmembrane transport;GO:0050909 sensory perception of taste", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q8IMN5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q8INF0-1", "uniprot_id": "GCY8E_DROME", "mass": 121201.0, "length": 1097, "protein_name": "Soluble guanylate cyclase 88E", "gene_name": "Gyc88E", "organism": "Fruit fly", "refseq_name": "guanylyl cyclase at 88E, isoform D", "refseq_ac": "NP_001036711", "gene_names_uniprotkb": "Gyc88E; CG4154", "gene_names_refseq": "CG4154; Dmel\\CG4154; GYC; Gyc-88E; Gyc88E", "protein_names_uniprotkb": "Soluble guanylate cyclase 88E; 4.6.1.2", "protein_names_refseq": "CG4154-PD; Gyc88E-PD; guanylyl cyclase at 88E, isoform D", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG4154)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "10731132;12537572;15159437;15485853", "class_list": "", "function": "Heterodimers with Gyc-89Da and Gyc-89Db are activated in response to changing oxygen concentrations, alerting flies to hypoxic environments. Under normal oxygen concentrations, oxygen binds to the heme group and results in low levels of guanylyl cyclase activity. When exposed to reduced oxygen concentrations, the oxygen dissociates from the heme group resulting in activation of the enzyme., [UniProtKB, PubMed]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "A2RVE6;Q0KI72;Q6U839;Q6U840;Q9VFC5", "ec_number_list": "4.6.1.2", "go_molecular_function": "GO:0003924 GTPase activity;GO:0004383 guanylate cyclase activity;GO:0005525 GTP binding;GO:0019899 enzyme binding;GO:0042803 protein homodimerization activity", "go_cellular_component": "GO:0008074 guanylate cyclase complex, soluble", "go_biological_process": "GO:0001666 response to hypoxia;GO:0000302 response to reactive oxygen species;GO:0038060 nitric oxide-cGMP-mediated signaling;GO:0070482 response to oxygen levels", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q8INF0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q8INF7-1", "uniprot_id": "DAAF5_DROME", "mass": 96290.0, "length": 845, "protein_name": "Dynein axonemal assembly factor 5", "gene_name": "Dnaaf5", "organism": "Fruit fly", "refseq_name": "dynein axonemal assembly factor 5", "refseq_ac": "NP_731905", "gene_names_uniprotkb": "Dnaaf5; CG31320; HEATR2", "gene_names_refseq": "CG31320; Dmel\\CG31320; Dnaaf5; HEATR2; Heatr2; NEST:bs27f03; fried", "protein_names_uniprotkb": "Dynein axonemal assembly factor 5; HEAT repeat-containing protein 2 homolog", "protein_names_refseq": "CG31320-PA; Dnaaf5-PA; HEAT repeat containing 2; dynein axonemal assembly factor 5; fried", "tax_id": 7227, "disease": "primary ciliary dyskinesia 18 (Disease Ontology:DOID:0110604); male infertility (Disease Ontology:DOID:12336); primary ciliary dyskinesia (Disease Ontology:DOID:9562)", "pathway": " (dme:Dmel_CG31320)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "10731132;12537572;25232951", "class_list": "", "function": "Cytoplasmic protein involved in the delivery of the dynein machinery to the motile cilium. It is required for the assembly of the axonemal dynein inner and outer arms, two structures attached to the peripheral outer doublet A microtubule of the axoneme, that play a crucial role in cilium motility., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0045505 dynein intermediate chain binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0120293 dynein axonemal particle", "go_biological_process": "GO:0060294 cilium movement involved in cell motility;GO:0008344 adult locomotory behavior;GO:0030317 flagellated sperm motility;GO:0007605 sensory perception of sound;GO:0003341 cilium movement", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q8INF7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q8INM9-1", "uniprot_id": "GR85A_DROME", "mass": 46080.0, "length": 397, "protein_name": "Putative gustatory receptor 85a", "gene_name": "Gr85a", "organism": "Fruit fly", "refseq_name": "gustatory receptor 85a", "refseq_ac": "NP_731426", "gene_names_uniprotkb": "Gr85a; CG31405", "gene_names_refseq": "CG31405; Dmel\\CG31405; Gr85a", "protein_names_uniprotkb": "Putative gustatory receptor 85a", "protein_names_refseq": "CG31405-PA; Gr85a-PA; gustatory receptor 85a", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG31405)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "10731132;11516643;12537572", "class_list": "", "function": "Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0015276 ligand-gated monoatomic ion channel activity;GO:0008527 taste receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane;GO:0030424 axon;GO:0030425 dendrite;GO:0043025 neuronal cell body", "go_biological_process": "GO:0007165 signal transduction;GO:0034220 monoatomic ion transmembrane transport;GO:0050909 sensory perception of taste", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q8INM9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q8INT5-1", "uniprot_id": "DAAF1_DROME", "mass": 168194.0, "length": 1483, "protein_name": "Dynein axonemal assembly factor 1 homolog", "gene_name": "dtr", "organism": "Fruit fly", "refseq_name": "defective transmitter release", "refseq_ac": "NP_724335", "gene_names_uniprotkb": "dtr; CG31623", "gene_names_refseq": "CG31623; Dmel\\CG31623; Dtr; dtr", "protein_names_uniprotkb": "Dynein axonemal assembly factor 1 homolog; Defective transmitter-recycling protein; Leucine-rich repeat-containing protein 50 homolog", "protein_names_refseq": "CG31623-PA; defective transmitter release; dtr-PA", "tax_id": 7227, "disease": "idiopathic scoliosis (Disease Ontology:DOID:0060250); primary ciliary dyskinesia 13 (Disease Ontology:DOID:0110618); seminoma (Disease Ontology:DOID:4440); testicular germ cell cancer (Disease Ontology:DOID:5557); autosomal dominant polycystic kidney disease (Disease Ontology:DOID:898)", "pathway": " (dme:Dmel_CG31623)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "10731132;12537572;40245499", "class_list": "", "function": "Cilium-specific protein required for cilia structures., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 5, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q6YNS3", "ec_number_list": "", "go_molecular_function": "GO:0070840 dynein complex binding", "go_cellular_component": "GO:0045202 synapse;GO:0005930 axoneme", "go_biological_process": "GO:0007268 chemical synaptic transmission;GO:0060271 cilium assembly;GO:0007368 determination of left/right symmetry;GO:0035082 axoneme assembly", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q8INT5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q8IPU5-1", "uniprot_id": "GR77A_DROME", "mass": 51955.0, "length": 449, "protein_name": "Putative gustatory receptor 77a", "gene_name": "Gr77a", "organism": "Fruit fly", "refseq_name": "gustatory receptor 77a", "refseq_ac": "NP_730560", "gene_names_uniprotkb": "Gr77a; CG32433; GR77E.1", "gene_names_refseq": "77E.1; CG32433; Dmel\\CG32433; GR77E.1; GR77a; Gr77E1; Gr77a", "protein_names_uniprotkb": "Putative gustatory receptor 77a", "protein_names_refseq": "CG32433-PA; Gr77a-PA; gustatory receptor 77E.1; gustatory receptor 77a", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG32433)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "10710312;10731132;11516643;12537572;22031876", "class_list": "", "function": "Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0015276 ligand-gated monoatomic ion channel activity;GO:0008527 taste receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane;GO:0030424 axon;GO:0030425 dendrite;GO:0043025 neuronal cell body", "go_biological_process": "GO:0008049 male courtship behavior;GO:0007165 signal transduction;GO:0034220 monoatomic ion transmembrane transport;GO:0007635 chemosensory behavior;GO:0050909 sensory perception of taste", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q8IPU5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q8IPX7-1", "uniprot_id": "EXOS3_DROME", "mass": 25026.0, "length": 232, "protein_name": "Exosome complex component RRP40", "gene_name": "Rrp40", "organism": "Fruit fly", "refseq_name": "ribosomal RNA processing 40, isoform B", "refseq_ac": "NP_001285565", "gene_names_uniprotkb": "Rrp40; CG31938", "gene_names_refseq": "CG31938; Dmel\\CG31938; Rrp40; dRrp40", "protein_names_uniprotkb": "Exosome complex component RRP40; Ribosomal RNA-processing protein 40", "protein_names_refseq": "CG31938-PB; Rrp40-PB; ribosomal RNA processing 40, isoform B", "tax_id": 7227, "disease": "pontocerebellar hypoplasia type 1B (Disease Ontology:DOID:0060266); stomach cancer (Disease Ontology:DOID:10534)", "pathway": " (dme:Dmel_CG31938); (R-DME-429958); (R-DME-450385); (R-DME-450513); (R-DME-6791226); (R-DME-9930044)", "pathway_count": 6, "publication_count": 5, "publication_id_list": "10731132;12490954;12537572;25892215;32645003", "class_list": "", "function": "Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events (By similarity). In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts such as antisense RNA species, and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm (By similarity). In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs (By similarity). The catalytic inactive RNA exosome core complex of 9 subunits is proposed to play a pivotal role in the binding and presentation of RNA for ribonucleolysis, and to serve as a scaffold for the association with catalytic subunits and accessory proteins or complexes (By similarity). Required generally for normal embryonic and neuronal development (PubMed:32645003). Also plays a critical role in the maintenance of neuronal function in mature flies by controlling the levels of specific mRNAs such as the synaptic regulator Arc1 (PubMed:32645003)., [UniProtKB, UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0000176 nuclear exosome (RNase complex);GO:0000177 cytoplasmic exosome (RNase complex)", "go_biological_process": "GO:0007420 brain development;GO:0010468 regulation of gene expression;GO:0000956 nuclear-transcribed mRNA catabolic process;GO:0045995 regulation of embryonic development;GO:0006401 RNA catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q8IPX7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q8IQ92-1", "uniprot_id": "Q8IQ92_DROME", "mass": 12139.0, "length": 106, "protein_name": "Heterochromatin protein 4, isoform A", "gene_name": "HP4", "organism": "Fruit fly", "refseq_name": "heterochromatin protein 4, isoform A", "refseq_ac": "NP_648166", "gene_names_uniprotkb": "HP4; BcDNA:GM01628; CG8044; Dmel\\CG8044; Dmel_CG8044; Hip; hip", "gene_names_refseq": "BcDNA:GM01628; CG8044; Dmel\\CG8044; HP4; Hip; hip", "protein_names_uniprotkb": "Heterochromatin protein 4, isoform A", "protein_names_refseq": "CG8044-PA; HP1-interacting protein; HP4-PA; heterochromatin protein 4, isoform A; heterochromatin protein 4", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG8044)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005730 nucleolus;GO:0000792 heterochromatin;GO:0010369 chromocenter;GO:0000781 chromosome, telomeric region", "go_biological_process": "GO:0006325 chromatin organization", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q8IQ92-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q8IQG1-1", "uniprot_id": "MOB2_DROME", "mass": 58907.0, "length": 566, "protein_name": "MOB kinase activator-like 2", "gene_name": "Mob2", "organism": "Fruit fly", "refseq_name": "Mob2, isoform E", "refseq_ac": "NP_001261713", "gene_names_uniprotkb": "Mob2; CG11711", "gene_names_refseq": "BEST:GH06341; BcDNA:GH13236; CG11711; CG11712; DMob2; Dmel\\CG11711; Dmob1; Dmob2; Mob1; Mob2; MobI; dmob2; gh06341; trezor", "protein_names_uniprotkb": "MOB kinase activator-like 2; Dmob2; Mob as tumor suppressor protein 2; Mps one binder kinase activator-like 2", "protein_names_refseq": "CG11711-PE; Mob2, isoform E; Mob2-PE", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG11711)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "10731132;12537569;12537572;15975907;17018572", "class_list": "", "function": "Required for the normal morphogenesis of a variety of polarized outgrowths including epidermal hairs, bristles, arista laterals, and dendrites., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q5BHY7;Q8IGB4;Q8IQG2;Q9VTJ6;Q9VTJ7", "ec_number_list": "", "go_molecular_function": "GO:0019901 protein kinase binding;GO:0046872 metal ion binding;GO:0030295 protein kinase activator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0071944 cell periphery;GO:0016028 rhabdomere", "go_biological_process": "GO:0007165 signal transduction;GO:0000902 cell morphogenesis;GO:0007616 long-term memory;GO:0042052 rhabdomere development;GO:0045886 negative regulation of synaptic assembly at neuromuscular junction", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q8IQG1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q8IQQ4-1", "uniprot_id": "GORAB_DROME", "mass": 37707.0, "length": 338, "protein_name": "RAB6-interacting golgin", "gene_name": "Gorab", "organism": "Fruit fly", "refseq_name": "Golgin, RAB6 interacting", "refseq_ac": "NP_788523", "gene_names_uniprotkb": "Gorab; CG33052", "gene_names_refseq": "CG33052; CG3882; Dmel\\CG33052; Gorab; gorab", "protein_names_uniprotkb": "RAB6-interacting golgin", "protein_names_refseq": "CG33052-PA; Golgin, RAB6 interacting; Gorab-PA", "tax_id": 7227, "disease": "geroderma osteodysplasticum (Disease Ontology:DOID:0111266)", "pathway": " (dme:Dmel_CG33052)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "10731132;12537569;12537572;29892014;33704067", "class_list": "", "function": "Required for centriole duplication likely through its interaction with Sas-6 (PubMed:29892014, PubMed:33704067). During embryogenesis, maternally provided protein is required for centrosome duplication and nuclear division cycles of the syncytial embryos (PubMed:29892014). In femoral chordotonal organs, required for sensory cilia structural integrity and functionality necessary for motor coordination (PubMed:29892014). In male germline, has a role in cytokinesis which seems dependent on its localization to the Golgi (PubMed:29892014)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 22, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q8SZQ5", "ec_number_list": "", "go_molecular_function": "GO:0042802 identical protein binding", "go_cellular_component": "GO:0005813 centrosome;GO:0005814 centriole;GO:0005802 trans-Golgi network;GO:0031985 Golgi cisterna", "go_biological_process": "GO:0046601 positive regulation of centriole replication;GO:1905515 non-motile cilium assembly;GO:0032467 positive regulation of cytokinesis;GO:0045724 positive regulation of cilium assembly", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q8IQQ4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q8IR45-1", "uniprot_id": "BORC8_DROME", "mass": 20937.0, "length": 183, "protein_name": "BLOC-1-related complex subunit 8 homolog", "gene_name": "CG32590", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": "NP_727796", "gene_names_uniprotkb": "CG32590", "gene_names_refseq": "CG32590; Dmel\\CG32590", "protein_names_uniprotkb": "BLOC-1-related complex subunit 8 homolog", "protein_names_refseq": "CG32590-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG32590)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "10731132;12537572", "class_list": "", "function": "May participate in the coupling of lysosomes to microtubule plus-end-directed kinesin motor., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0098574 cytoplasmic side of lysosomal membrane;GO:0099078 BORC complex", "go_biological_process": "GO:0032418 lysosome localization;GO:0072384 organelle transport along microtubule", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q8IR45-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q8IRB5-1", "uniprot_id": "CLSPN_DROME", "mass": 165283.0, "length": 1465, "protein_name": "Claspin", "gene_name": "Claspin", "organism": "Fruit fly", "refseq_name": "claspin, isoform B", "refseq_ac": "NP_001286934", "gene_names_uniprotkb": "Claspin; CG32251", "gene_names_refseq": "CG1326; CG32251; Claspin; Dmel\\CG32251; claspin", "protein_names_uniprotkb": "Claspin", "protein_names_refseq": "CG32251-PB; Claspin-PB; claspin, isoform B", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG32251); (R-DME-111465); (R-DME-176187)", "pathway_count": 3, "publication_count": 6, "publication_id_list": "10731132;12537569;12537572;17372656;18327897;22796626", "class_list": "", "function": "Required for checkpoint signaling in response to DNA replication stress; either resulting from normal embryogenesis or induced by the DNA synthesis inhibitor hydroxyurea (HU). It is not required for the G2 arrest resulting from DNA double strand breaks induced by ionizing irradiation (IR). Necessary for the timely phosphorylation of Cdk1 at the mid-blastula transition. May have a minor role in maintaining genomic stability in mitotic cells., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 25, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q8MYR6;X2JAN5", "ec_number_list": "", "go_molecular_function": "GO:0010997 anaphase-promoting complex binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0007095 mitotic G2 DNA damage checkpoint signaling;GO:0033314 mitotic DNA replication checkpoint signaling", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q8IRB5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q8IRY7-1", "uniprot_id": "CASP8_DROME", "mass": 56153.0, "length": 494, "protein_name": "Caspase-8", "gene_name": "Dredd", "organism": "Fruit fly", "refseq_name": "death related ced-3/Nedd2-like caspase, isoform E", "refseq_ac": "NP_477249", "gene_names_uniprotkb": "Dredd; CASP8_DROME; CG7486; DCP-2; DCP2; DREDD; Dcp-2; Dcp2; Dedd; Dmel\\CG7486; Dmel_CG7486; Dredd; EG:115C2.9; Redd; anon-1BCa; dDredd; dredd", "gene_names_refseq": "CASP8_DROME; CG7486; DCP-2/DREDD; DCP-2; DCP2; DREDD; Dcp-2/Dredd; Dcp-2; Dcp2; Dedd; Dmel\\CG7486; Dredd/DCP-2; Dredd; EG:115C2.9; Redd; anon-1BCa; dDredd; dcp-2/dredd; dredd", "protein_names_uniprotkb": "Caspase-8; 3.4.22.61; Death-related ced-3/NEDD2-like protein", "protein_names_refseq": "CG7486-PE; Ced-3-like/Nedd2-like protein; Dredd-PE; death caspase-2; death related ced-3/Nedd2-like caspase, isoform E; death related ced-3/Nedd2-like protein; death-related ced-3/neural precursor cell expressed developmentally downregulated 2 (NEDD2)-like protein; drosophila caspase", "tax_id": 7227, "disease": "non-Hodgkin lymphoma (Disease Ontology:DOID:0060060); autoimmune lymphoproliferative syndrome type 2A (Disease Ontology:DOID:0110115); stomach cancer (Disease Ontology:DOID:10534)", "pathway": " (dme:Dmel_CG7486); (R-DME-111458); (R-DME-111459); (R-DME-198323); (R-DME-214397); (R-DME-214399); (R-DME-214411); (R-DME-214416); (R-DME-6803207); (R-DME-9627069); (R-DME-9948001); (R-DME-9948011)", "pathway_count": 12, "publication_count": 25, "publication_id_list": "10559939;10731132;10731137;10934188;11018014;11269502;12433364;12537568;12537569;12537572;12537573;12537574;12732719;15657141;16110336;16428381;16767093;17569856;17569867;22549468;25589440;26109356;26109357;9380701;9740659", "class_list": "", "function": "Effector of the programmed cell death (PCD) activators rpr, grim and hid (PubMed:9740659). May play an apoptotic role in the germline as well as soma. Fadd interacts with Dredd to promote cleavage of Dredd and is necessary and sufficient for enhancing Dredd-induced apoptosis (PubMed:10934188). Plays a role in the innate immune response. Required for resistance to Gram-negative bacterial infection (PubMed:11269502). Diap2-mediated ubiquitination of Dredd is critical for processing of imd and rel and the subsequent expression of antimicrobial genes such as DptA (PubMed:22549468)., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "O02433;O76797;O76798;Q95T94;Q9UB42;Q9W5E3", "ec_number_list": "3.4.22.-;2.7.11.24;2.3.2.27;2.7.11.1;3.4.22.61;2.7.11.10;4.2.1.109;3.4.22.62", "go_molecular_function": "GO:0008047 enzyme activator activity;GO:0004197 cysteine-type endopeptidase activity;GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0006508 proteolysis;GO:0006952 defense response;GO:0006955 immune response;GO:0016485 protein processing;GO:0045087 innate immune response", "synthesized_glycan_count": 0, "hit_score": 2.6, "record_id": "Q8IRY7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q8MPP3-1", "uniprot_id": "D2MP_DROME", "mass": 89137.0, "length": 758, "protein_name": "Matrix metalloproteinase-2", "gene_name": "Mmp2", "organism": "Fruit fly", "refseq_name": "matrix metalloproteinase 2, isoform C", "refseq_ac": "NP_001260830", "gene_names_uniprotkb": "Mmp2; CG1794", "gene_names_refseq": "2-MMP; CG1794; Dm2-MMP; Dmel\\CG1794; MMP2; Mmp2; SN2-2; anon-WO0118547.84; dMMP2; dm-2MMP; dmmp2; l(2)02353; mmp2", "protein_names_uniprotkb": "Matrix metalloproteinase-2; 3.4.24.-; Dm2-MMP", "protein_names_refseq": "CG1794-PC; Mmp2-PC; matrix metalloprotease 2; matrix metalloproteinase 2, isoform C; matrix metalloproteinase 2; matrix metalloproteinase-2; matrix metalloprotinase 2; suppressor of NA9 2-2", "tax_id": 7227, "disease": "Winchester syndrome (Disease Ontology:DOID:0080696); amelogenesis imperfecta hypomaturation type 2A2 (Disease Ontology:DOID:0110060); prostate cancer (Disease Ontology:DOID:10283); intracranial aneurysm (Disease Ontology:DOID:10941); diabetic angiopathy (Disease Ontology:DOID:11713); dilated cardiomyopathy (Disease Ontology:DOID:12930); thoracic aortic aneurysm (Disease Ontology:DOID:14004); Marfan syndrome (Disease Ontology:DOID:14323); brain ischemia (Disease Ontology:DOID:2316); arteriosclerosis (Disease Ontology:DOID:2349); transitional cell carcinoma (Disease Ontology:DOID:2671); IgA glomerulonephritis (Disease Ontology:DOID:2986); ischemia (Disease Ontology:DOID:326); brain infarction (Disease Ontology:DOID:3454); breast carcinoma (Disease Ontology:DOID:3459); esophagus squamous cell carcinoma (Disease Ontology:DOID:3748); anti-basement membrane glomerulonephritis (Disease Ontology:DOID:4780); esophagus adenocarcinoma (Disease Ontology:DOID:4914); myocardial infarction (Disease Ontology:DOID:5844); congestive heart failure (Disease Ontology:DOID:6000); rheumatoid arthritis (Disease Ontology:DOID:7148); abdominal aortic aneurysm (Disease Ontology:DOID:7693)", "pathway": " (dme:Dmel_CG1794); (R-DME-1442490); (R-DME-1474228); (R-DME-1592389); (R-DME-2022090); (R-DME-2179392); (R-DME-3928665); (R-DME-6798695)", "pathway_count": 8, "publication_count": 14, "publication_id_list": "10731132;11967260;12530966;12537572;18045838;19751719;20412776;21471368;22262460;22496930;25267296;25520167;25695427;31350199", "class_list": "", "function": "Has metalloproteinase activity (PubMed:11967260). Proteolytically cleaves the PGRP-LC receptor; involved in gut-fat body innate immunological communication (GFIC)-mediated activation of the imd/Relish signal transduction pathway (PubMed:22262460, PubMed:31350199). Required for larval tissue histolysis during metamorphosis and is involved in pupal head eversion and fusion of the wing imaginal tissue (PubMed:12530966). Required for growth of the dorsal air sac primordium and development of the dorsal air sacs (PubMed:19751719). Promotes embryonic motor axon fasciculation (PubMed:18045838). Cleaves and activates frac to promote motor axon bundling during outgrowth (PubMed:21471368). Promotes the reshaping of adult sensory neuron dendrites from a radial to lattice-like shape which occurs after eclosion by degrading the basement membrane on which the dendrites grow (PubMed:20412776). Involved in inhibition of follicle stem cell proliferation by cleaving Dlp, inhibiting its interaction with wg and preventing Dlp-mediated spreading of wg to follicle stem cells to enhance their proliferation (PubMed:25267296). Plays a role in wound healing (PubMed:22262460). Involved in fat body dissociation which occurs during metamorphosis by degrading basement membrane components, leading to destruction of cell-basement membrane junctions (PubMed:25520167). Required for posterior follicle cell degradation and ovulation (PubMed:25695427)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 22, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A0B4KFG9;A0A0C4DHC9;Q5BIL2", "ec_number_list": "2.4.1.186;1.2.1.-;1.2.1.3;1.-.-.-;3.4.21.-;5.4.2.7;5.4.2.-;3.2.1.17;3.2.1.31;7.6.2.1;3.4.24.-;3.1.4.4;1.1.1.42;3.5.1.28;6.2.1.3;3.2.1.14;2.4.2.1;2.7.11.24;2.7.1.40;3.5.3.1;3.6.5.2;2.7.11.13;4.1.2.13;2.7.4.6;3.6.5.-;1.11.1.6;3.4.21.75;3.1.3.48;5.3.1.9;2.7.1.11;1.1.1.205;3.4.22.-;3.6.4.12;3.6.4.6;1.16.3.1;2.7.1.35;2.3.2.5;3.4.19.9;1.14.19.17;3.4.22.15;2.3.2.27;2.7.1.1;5.2.1.8;3.4.19.-;1.11.1.24;5.6.1.5;2.7.10.1;2.7.10.2;5.4.2.11;5.4.2.4;3.2.1.23;3.6.1.5;3.5.1.3;3.6.4.13;3.3.2.6;3.4.24.81;3.5.4.5;2.7.11.22;2.7.11.23;4.2.1.24;5.4.2.2;3.4.-.-;2.3.1.51;3.4.17.13;3.2.1.-;2.7.11.1;2.4.1.25;3.2.1.33;2.7.1.-;2.3.1.78;3.5.4.6;2.3.2.26", "go_molecular_function": "GO:0004175 endopeptidase activity;GO:0004222 metalloendopeptidase activity;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005886 plasma membrane;GO:0030425 dendrite;GO:0031012 extracellular matrix;GO:0009897 external side of plasma membrane", "go_biological_process": "GO:0046331 lateral inhibition;GO:2000647 negative regulation of stem cell proliferation;GO:0016485 protein processing;GO:0030198 extracellular matrix organization;GO:0090090 negative regulation of canonical Wnt signaling pathway", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "Q8MPP3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q8MQX9-1", "uniprot_id": "ANKL2_DROME", "mass": 129082.0, "length": 1174, "protein_name": "Ankyrin repeat and LEM domain-containing protein 2 homolog", "gene_name": "Ankle2", "organism": "Fruit fly", "refseq_name": "Ankle2, isoform G", "refseq_ac": "NP_001285375", "gene_names_uniprotkb": "Ankle2; CG8465; l(1)G0222; l(1)G0316", "gene_names_refseq": "Ankle-2; Ankle2; CG8465; Dmel\\CG8465; anon-WO03040301.175; anon-WO03040301.177; anon-WO03040301.179; dAnkle2; l(1)G0222; l(1)G0316", "protein_names_uniprotkb": "Ankyrin repeat and LEM domain-containing protein 2 homolog", "protein_names_refseq": "ANKLE2 ortholog; Ankle2, isoform G; Ankle2-PG; CG8465-PG; ankyrin repeat and LEM domain containing 2; l(1)G0222; lethal (1) G0222", "tax_id": 7227, "disease": "primary autosomal recessive microcephaly 16 (Disease Ontology:DOID:0070289); microcephaly (Disease Ontology:DOID:10907)", "pathway": " (dme:Dmel_CG8465); (R-DME-2995383)", "pathway_count": 2, "publication_count": 6, "publication_id_list": "10731132;12537569;12537572;25259927;30550790;31735666", "class_list": "", "function": "Involved in brain development probably by regulating asymmetric division of neuroblasts (PubMed:25259927, PubMed:30550790, PubMed:31735666). Regulates neuroblast asymmetric cell division by controlling asymmetric protein localization of Mira, Baz, Par-6 and aPKC, and spindle alignment (PubMed:31735666). Also, regulates the localization of kinase Ball during mitosis, specifically maintaining Ball in the nucleus during interphase (PubMed:31735666). Required for proper ER and nuclear envelope morphology in neuroblasts (PubMed:31735666)., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "Q0KHR1;Q9VX44;X2JCC5", "ec_number_list": "", "go_molecular_function": "GO:0051721 protein phosphatase 2A binding", "go_cellular_component": "GO:0005635 nuclear envelope;GO:0005737 cytoplasm;GO:0005783 endoplasmic reticulum;GO:0012505 endomembrane system", "go_biological_process": "GO:0031468 nuclear membrane reassembly;GO:0007084 mitotic nuclear membrane reassembly;GO:0051653 spindle localization;GO:0055059 asymmetric neuroblast division;GO:0007029 endoplasmic reticulum organization", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q8MQX9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q8MR37-1", "uniprot_id": "KLFL_DROME", "mass": 61770.0, "length": 570, "protein_name": "Krueppel-like factor luna", "gene_name": "luna", "organism": "Fruit fly", "refseq_name": "luna, isoform C", "refseq_ac": "NP_001260879", "gene_names_uniprotkb": "luna; CG33473", "gene_names_refseq": "CG17326; CG33473; CG9087; DKLF; Dmel\\CG33473; KLF; Klf; LUNA; Luna; lincRNA.284; luna", "protein_names_uniprotkb": "Krueppel-like factor luna", "protein_names_refseq": "CG33473-PC; luna, isoform C; luna-PC", "tax_id": 7227, "disease": "prostate cancer (Disease Ontology:DOID:10283); stomach cancer (Disease Ontology:DOID:10534)", "pathway": " (dme:Dmel_CG33473)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "10731132;12537572;14527717;24915236", "class_list": "", "function": "Probable transcription factor that is required for cell differentiation (PubMed:14527717, PubMed:24915236). Essential for proper separation of the sister chromatids during early nuclear division cycles in the syncytial pre-blastoderm embryo (PubMed:24915236)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0043565 sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0051301 cell division;GO:0000070 mitotic sister chromatid segregation;GO:0035185 preblastoderm mitotic cell cycle", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q8MR37-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q8MR45-1", "uniprot_id": "ASPG1_DROME", "mass": 42240.0, "length": 393, "protein_name": "Putative N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase CG1827", "gene_name": "CG1827", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": "NP_610504", "gene_names_uniprotkb": "CG1827", "gene_names_refseq": "CG1827; Dmel\\CG1827; cg1827", "protein_names_uniprotkb": "Putative N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase CG1827; 3.5.1.26; AGA; Aspartylglucosaminidase; Glycosylasparaginase; N4-(N-acetyl-beta-glucosaminyl)-L-asparagine amidase", "protein_names_refseq": "CG1827-PD; uncharacterized protein", "tax_id": 7227, "disease": "aspartylglucosaminuria (Disease Ontology:DOID:0050461); lysosomal storage disease (Disease Ontology:DOID:3211)", "pathway": " (dme:Dmel_CG1827); (R-DME-6798695)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "10731132;12537569;12537572", "class_list": "", "function": "Cleaves the GlcNAc-Asn bond which joins oligosaccharides to the peptide of asparagine-linked glycoproteins., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "A1Z7W5;A1Z7W6;Q6NN89", "ec_number_list": "3.5.2.17;3.2.1.17;3.2.1.31;3.5.3.1;2.7.11.24;2.7.11.13;1.1.1.205;3.6.4.6;1.16.3.1;3.2.1.-;3.4.19.9;3.5.1.26;5.3.99.3;2.7.10.2;3.2.1.23;6.3.4.21;4.6.1.19;3.2.1.51;3.5.4.4;1.11.2.-;2.4.1.1;1.6.2.2", "go_molecular_function": "GO:0008233 peptidase activity;GO:0003948 N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005764 lysosome", "go_biological_process": "GO:0006508 proteolysis;GO:0006517 protein deglycosylation", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q8MR45-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q8MRC9-1", "uniprot_id": "GALT9_DROME", "mass": 73193.0, "length": 650, "protein_name": "Putative polypeptide N-acetylgalactosaminyltransferase 9", "gene_name": "Pgant9", "organism": "Fruit fly", "refseq_name": "polypeptide N-Acetylgalactosaminyltransferase 9, isoform C", "refseq_ac": "NP_001097341", "gene_names_uniprotkb": "Pgant9; CG30463", "gene_names_refseq": "CG15713; CG30463; CG8456; CG8463; Dmel\\CG30463; PGANT9; Pgant9; dppGalNAcT9; pgant9", "protein_names_uniprotkb": "Putative polypeptide N-acetylgalactosaminyltransferase 9; 2.4.1.41; Protein-UDP acetylgalactosaminyltransferase 9; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 9; pp-GaNTase 9", "protein_names_refseq": "CG30463-PC; Pgant9-PC; polypeptide N-Acetylgalactosaminyltransferase 9, isoform C", "tax_id": 7227, "disease": "hyperphosphatemic familial tumoral calcinosis (Disease Ontology:DOID:0111063); colorectal cancer (Disease Ontology:DOID:9256)", "pathway": " (dme:Dmel_CG30463)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "10731132;12537569;12537572;16251381;22157008;30158631", "class_list": "", "function": "Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor (PubMed:30158631). It can both act as a peptide transferase that transfers GalNAc onto unmodified peptide substrates, and as a glycopeptide transferase that requires the prior addition of a GalNAc on a peptide before adding additional GalNAc moieties (PubMed:30158631)., [UniProtKB, PubMed]; N-acetylgalactosaminyltransferase which preferentially O-glycosylates negatively charge substrates. O-glycosylates mucin-like protein Sgs3 in the salivary gland but to a lesser extent than isoform B. By regulating the O-glycosylation of secretory cargo proteins plays a role in the morphology and maturation of salivary gland secretory granules., [UniProtKB, PubMed]; N-acetylgalactosaminyltransferase which preferentially O-glycosylates positively charge substrates. O-glycosylates mucin-like protein Sgs3 in the salivary gland. By regulating the O-glycosylation of secretory cargo proteins, plays a role in the morphology and maturation of salivary gland secretory granules., [UniProtKB, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 1, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 1, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 1, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 1, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "A1A6R7;A1A6V9;A8DYG1;A8DYG2;A8DYG3;Q0E950;Q9V7T0", "ec_number_list": "2.4.1.-;2.4.1.41", "go_molecular_function": "GO:0046872 metal ion binding;GO:0030246 carbohydrate binding;GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005794 Golgi apparatus;GO:0016020 membrane;GO:0031985 Golgi cisterna", "go_biological_process": "GO:0006493 protein O-linked glycosylation;GO:0016266 protein O-linked glycosylation via N-acetyl-galactosamine", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q8MRC9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q8MRW5-1", "uniprot_id": "ET96B_DROME", "mass": 70284.0, "length": 640, "protein_name": "ETV5-related protein Ets96B", "gene_name": "Ets96B", "organism": "Fruit fly", "refseq_name": "Ets96B, isoform C", "refseq_ac": "NP_651286", "gene_names_uniprotkb": "Ets96B; CG6892", "gene_names_refseq": "CG6892; Dmel\\CG6892; ETS96B; Ets96B; Ets; ets96B", "protein_names_uniprotkb": "ETV5-related protein Ets96B", "protein_names_refseq": "CG6892-PC; Ets96B, isoform C; Ets96B-PC", "tax_id": 7227, "disease": "bipolar disorder (Disease Ontology:DOID:3312); obesity (Disease Ontology:DOID:9970)", "pathway": " (dme:Dmel_CG6892); (R-DME-5687128)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "10731132;12537572;27280443", "class_list": "", "function": "Required in dopaminergic neurons to regulate expression of genes involved in dopamine signaling. Decreases expression of the dopamine transporter DAT and increases expression of the dopamine transporter Vmat and the tyrosine 3-monooxygenase ple which is involved in dopamine biosynthesis. Also involved in negatively regulating the expression of a group of endoplasmic reticulum proteins, the molecular chaperone Calr and the protein disulfide isomerases CaBP1 and ERp60., [UniProtKB, PubMed]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "Q9VC38", "ec_number_list": "", "go_molecular_function": "GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0043565 sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0001964 startle response;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0030154 cell differentiation;GO:0042594 response to starvation", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q8MRW5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q8MT06-1", "uniprot_id": "GNL3_DROME", "mass": 65985.0, "length": 581, "protein_name": "Guanine nucleotide-binding protein-like 3 homolog", "gene_name": "Ns1", "organism": "Fruit fly", "refseq_name": "nucleostemin 1", "refseq_ac": "NP_732199", "gene_names_uniprotkb": "Ns1; CG3983", "gene_names_refseq": "CG3983; Dmel\\CG3983; NS1; Ns1; dmNS1; ns1", "protein_names_uniprotkb": "Guanine nucleotide-binding protein-like 3 homolog; Nucleostemin 1; Nucleostemin homolog", "protein_names_refseq": "CG3983-PA; Ns1-PA; nucleostemin 1; nucleostemin ortholog 1; nucleostemin1", "tax_id": 7227, "disease": "obesity (Disease Ontology:DOID:9970)", "pathway": " (dme:Dmel_CG3983); (R-DME-6791226)", "pathway_count": 2, "publication_count": 5, "publication_id_list": "10731132;12537569;12537572;17372656;18628395", "class_list": "", "function": "May play a role in regulating cellular proliferation., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A4V308;B6IDZ0;Q9VEN7", "ec_number_list": "", "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0016887 ATP hydrolysis activity", "go_cellular_component": "GO:0005730 nucleolus;GO:0001652 granular component", "go_biological_process": "GO:0040014 regulation of multicellular organism growth;GO:0042127 regulation of cell population proliferation;GO:0042273 ribosomal large subunit biogenesis", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q8MT06-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q8MT08-1", "uniprot_id": "DRC4_DROME", "mass": 57168.0, "length": 479, "protein_name": "Dynein regulatory complex subunit 4", "gene_name": "Gas8", "organism": "Fruit fly", "refseq_name": "growth arrest specific protein 8, isoform C", "refseq_ac": "NP_001284840", "gene_names_uniprotkb": "Gas8; CG14271; Dmel\\CG14271; Dmel_CG14271; GAS8", "gene_names_refseq": "CG14271; Dmel\\CG14271; GAS8; Gas8", "protein_names_uniprotkb": "Dynein regulatory complex subunit 4; Growth arrest-specific protein 8", "protein_names_refseq": "CG14271-PC; Gas8-PC; growth arrest specific protein 8, isoform C", "tax_id": 7227, "disease": "primary ciliary dyskinesia 33 (Disease Ontology:DOID:0110619)", "pathway": " (dme:Dmel_CG14271)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "10731132;11751847;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "Cytoskeletal linker which probably functions in axonemal and non-axonemal dynein regulation. May play a role in the spermatozoa motility (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q8T9R5;Q9W4R6", "ec_number_list": "", "go_molecular_function": "GO:0008017 microtubule binding;GO:0031267 small GTPase binding", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0005874 microtubule;GO:0031514 motile cilium;GO:0036064 ciliary basal body", "go_biological_process": "GO:0045880 positive regulation of smoothened signaling pathway;GO:0060294 cilium movement involved in cell motility;GO:0030317 flagellated sperm motility;GO:0035082 axoneme assembly;GO:0048870 cell motility", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "Q8MT08-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q8MUJ1-1", "uniprot_id": "EIGER_DROME", "mass": 46918.0, "length": 415, "protein_name": "Tumor necrosis factor family member eiger", "gene_name": "egr", "organism": "Fruit fly", "refseq_name": "eiger, isoform A", "refseq_ac": "NP_724878", "gene_names_uniprotkb": "egr; CG12919; Darth", "gene_names_refseq": "BcDNA:RH51659; CG12919; Dmel\\CG12919; EGR; Ect1; Egr; Eiger; Eig; Regg1; TNF-alpha; TNFalpha; TNF; darth; dt1; egr; regg1", "protein_names_uniprotkb": "Tumor necrosis factor family member eiger; Protein eiger", "protein_names_refseq": "CG12919-PA; Eiger, tumour necrosis factor family member; TNF-alpha; drosophila aspartate rich TNF homolog; egr-PA; eiger, isoform A; eiger; tumor necrosis factor family member DT1; wengen", "tax_id": 7227, "disease": "tooth agenesis (Disease Ontology:DOID:0050591); ectodermal dysplasia 1 (Disease Ontology:DOID:0111664); hypohidrotic ectodermal dysplasia (Disease Ontology:DOID:14793); carcinoma (Disease Ontology:DOID:305)", "pathway": " (dme:Dmel_CG12919); (R-DME-450520)", "pathway_count": 2, "publication_count": 20, "publication_id_list": "10731132;12065414;12084706;12176339;12537569;12537572;12894227;17356067;17381241;19019992;19289090;19375319;20505310;20627081;24066226;25754009;25874673;27076079;33824334;38944657", "class_list": "", "function": "Cytokine which acts as a ligand for wgn (PubMed:12084706, PubMed:12894227, PubMed:33824334). Also acts as a ligand for grnd (PubMed:25874673, PubMed:27076079, PubMed:33824334). Induces apoptosis by triggering JNK signaling (PubMed:12065414, PubMed:12176339, PubMed:12894227). Together with grnd, involved in egr-dependent apoptosis in wing imaginal discs during development (PubMed:33824334). Required for JNK-dependent non-autonomous apoptosis through release from apoptotic cells and activation of apoptosis in neighboring cells (PubMed:24066226). Required for JNK-independent damage-induced apoptosis in the embryonic central nervous system through regulation of the pro-apoptotic gene hid (PubMed:25754009). Involved in the innate immune response to extracellular pathogens (PubMed:17381241). Plays a role in the melanization immune response through its involvement in the rupture of crystal cells and subsequent release of prophenoloxidase (PubMed:17356067). Following UV-induced epidermal damage, released from apoptotic epidermal cells, binds to the wgn receptor on nociceptive sensory neurons and plays a role in development of thermal allodynia, a responsiveness to subthreshold thermal stimuli which are not normally perceived as noxious (PubMed:19375319). Involved in glial cell division induced by neuronal programmed cell death and injury (PubMed:19019992). Has tumor suppressor activity and eliminates oncogenic cells from epithelia, thereby maintaining epithelial integrity (PubMed:19289090). Under certain conditions can have tumor promoting properties by inducing cell proliferation and invasive spread (PubMed:20627081, PubMed:38944657). In the gut, involved in stress-induced stimulation of intestinal stem cell proliferation; produced in intestinal stem cells and enteroblasts to activate JNK signaling in enterocytes through interaction with its receptor grnd/grindelwald (PubMed:38944657). Involved in regulation of insulin production in response to dietary protein shortage keeping systemic growth in check (PubMed:27076079). Shed from fat body cells into the hemolymph in response to dietary amino acid shortage and activates the JNK siganling pathway in brain insulin producing cells by binding its receptor grnd, leading to inhibition of insulin production (PubMed:27076079)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 6, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "Q8IGD3;Q8MRW2;Q8MY88", "ec_number_list": "", "go_molecular_function": "GO:0005102 signaling receptor binding;GO:0005125 cytokine activity;GO:0048018 receptor ligand activity;GO:0032813 tumor necrosis factor receptor superfamily binding;GO:0005164 tumor necrosis factor receptor binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005886 plasma membrane;GO:0031410 cytoplasmic vesicle", "go_biological_process": "GO:1903427 negative regulation of reactive oxygen species biosynthetic process;GO:0006955 immune response;GO:0030335 positive regulation of cell migration;GO:0043065 positive regulation of apoptotic process;GO:0045087 innate immune response", "synthesized_glycan_count": 0, "hit_score": 2.1, "record_id": "Q8MUJ1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q8MV48-1", "uniprot_id": "GALT7_DROME", "mass": 68333.0, "length": 591, "protein_name": "N-acetylgalactosaminyltransferase 7", "gene_name": "Pgant7", "organism": "Fruit fly", "refseq_name": "polypeptide N-Acetylgalactosaminyltransferase 7, isoform C", "refseq_ac": "NP_001285406", "gene_names_uniprotkb": "Pgant7; CG6394; Dmel\\CG6394; Dmel_CG6394; GalNAc-T2; PGANT7; anon-WO02059370.15; dGalNAc-T2; pgant7", "gene_names_refseq": "CG6394; Dmel\\CG6394; GalNAc-T2; PGANT7; Pgant7; anon-WO02059370.15; dGalNAc-T2; pgant7", "protein_names_uniprotkb": "N-acetylgalactosaminyltransferase 7; 2.4.1.41; Protein-UDP acetylgalactosaminyltransferase 7; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 7; dGalNAc-T2; pp-GaNTase 7", "protein_names_refseq": "CG6394-PC; Pgant7-PC; UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2; polypeptide GalNAc transferase 7; polypeptide N-Acetylgalactosaminyltransferase 7, isoform C", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG6394); (R-DME-913709)", "pathway_count": 2, "publication_count": 17, "publication_id_list": "10731132;11925450;12537568;12537569;12537572;12537573;12537574;12829714;16110336;16251381;17569856;17569867;20807760;22157008;25589440;26109356;26109357", "class_list": "", "function": "Glycopeptide transferase involved in O-linked oligosaccharide biosynthesis, which catalyzes the transfer of an N-acetyl-D-galactosamine residue to an already glycosylated peptide (PubMed:11925450, PubMed:12829714). In contrast to other proteins of the family, it does not act as a peptide transferase that transfers GalNAc onto serine or threonine residue on the protein receptor, but instead requires the prior addition of a GalNAc on a peptide before adding additional GalNAc moieties (PubMed:11925450). Some peptide transferase activity is however not excluded, considering that its appropriate peptide substrate may remain unidentified. Prefers the monoglycosylated Muc5AC-3 as substrate (PubMed:11925450). Might have a role in protein O-glycosylation in the Golgi and thereby in establishing and/or maintaining a proper secretory apparatus structure (PubMed:20807760)., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "A4V4R2;Q5U0W9;Q95RJ3;Q95TN2;Q9VWT6", "ec_number_list": "2.4.1.-;2.4.1.41", "go_molecular_function": "GO:0046872 metal ion binding;GO:0030246 carbohydrate binding;GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity;GO:0016757 glycosyltransferase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005794 Golgi apparatus;GO:0012505 endomembrane system;GO:0005795 Golgi stack", "go_biological_process": "GO:0006493 protein O-linked glycosylation;GO:0016266 protein O-linked glycosylation via N-acetyl-galactosamine", "synthesized_glycan_count": 0, "hit_score": 1.8, "record_id": "Q8MV48-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q8MYY6-1", "uniprot_id": "GLT13_DROME", "mass": 64626.0, "length": 558, "protein_name": "Putative polypeptide N-acetylgalactosaminyltransferase 13", "gene_name": "pgant13", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": "NP_651630", "gene_names_uniprotkb": "pgant13; CG10000", "gene_names_refseq": "CG10000; Dmel\\CG10000; dppGalNAcT10", "protein_names_uniprotkb": "Putative polypeptide N-acetylgalactosaminyltransferase 13; 2.4.1.41; Protein-UDP acetylgalactosaminyltransferase 13; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 13; pp-GaNTase 13", "protein_names_refseq": "CG10000-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG10000); (R-DME-913709)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "10731132;12537569;12537572", "class_list": "", "function": "May catalyze the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor., [UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "Q9VAT9", "ec_number_list": "2.4.1.-;2.4.1.41", "go_molecular_function": "GO:0046872 metal ion binding;GO:0030246 carbohydrate binding;GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005794 Golgi apparatus", "go_biological_process": "GO:0006493 protein O-linked glycosylation;GO:0016266 protein O-linked glycosylation via N-acetyl-galactosamine;GO:0007618 mating", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q8MYY6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q8SWR2-1", "uniprot_id": "BICDR_DROME", "mass": 70236.0, "length": 620, "protein_name": "Bicaudal D-related protein homolog", "gene_name": "BicDR", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform B", "refseq_ac": "NP_729935", "gene_names_uniprotkb": "BicDR; CG17365; CG32137", "gene_names_refseq": "32137; CG17365; CG17366; CG32137; Dmel\\CG32137", "protein_names_uniprotkb": "Bicaudal D-related protein homolog; BICD-related protein homolog", "protein_names_refseq": "CG32137-PB; uncharacterized protein, isoform B", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG32137)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "10731132;12537569;12537572;38264934", "class_list": "", "function": "Functions redundantly with BicD (PubMed:38264934). Involved in formation and/or development of mechanosensory organs during metamorphosis (PubMed:38264934). During macrochaetae development, together with BicD, involved in Rab 6 and Spn-F stability and distribution and actin cytoskeleton organization (PubMed:38264934)., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q9VUA2;Q9VUA3", "ec_number_list": "", "go_molecular_function": "GO:0140312 cargo adaptor activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0098840 protein transport along microtubule;GO:0022416 chaeta development", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q8SWR2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q8SWV6-1", "uniprot_id": "FICD_DROME", "mass": 55725.0, "length": 492, "protein_name": "Protein adenylyltransferase Fic", "gene_name": "Fic", "organism": "Fruit fly", "refseq_name": "Fic domain-containing protein", "refseq_ac": "NP_609026", "gene_names_uniprotkb": "Fic; CG9523", "gene_names_refseq": "CG9523; Dmel\\CG9523; Fic; fic; l(2)k11101", "protein_names_uniprotkb": "Protein adenylyltransferase Fic; 2.7.7.108; 3.1.4.-; De-AMPylase Fic; dFic", "protein_names_refseq": "CG9523-PA; Fic domain-containing protein; Fic-PA; lethal (2) k11101", "tax_id": 7227, "disease": "hereditary spastic paraplegia 92 (Disease Ontology:DOID:0070644); hereditary spastic paraplegia (Disease Ontology:DOID:2476)", "pathway": " (dme:Dmel_CG9523)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "10731132;12537569;12537572;19503829;25395623;29089387", "class_list": "", "function": "Protein that can both mediate the addition of adenosine 5'-monophosphate (AMP) to specific residues of target proteins (AMPylation), and the removal of the same modification from target proteins (de-AMPylation), depending on the context (PubMed:29089387). The side chain of Glu-247 determines which of the two opposing activities (AMPylase or de-AMPylase) will take place (By similarity). Acts as a key regulator of the unfolded protein response (UPR) by mediating AMPylation or de-AMPylation of Hsc70-3/BiP (PubMed:25395623, PubMed:29089387). In unstressed cells, acts as an adenylyltransferase by mediating AMPylation of Hsc70-3/BiP at 'Thr-518', thereby inactivating it (PubMed:29089387). In response to endoplasmic reticulum stress, acts as a phosphodiesterase by mediating removal of ATP (de-AMPylation) from Hsc70-3/BiP at 'Thr-518', leading to restore HSPA5/BiP activity (PubMed:29089387)., [UniProtKB, PubMed, PubMed, UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 3, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9VMD8", "ec_number_list": "3.1.4.-;2.7.7.108", "go_molecular_function": "GO:0044603 protein adenylylhydrolase activity;GO:0005524 ATP binding;GO:0042803 protein homodimerization activity;GO:0051087 protein-folding chaperone binding;GO:0030544 Hsp70 protein binding", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005886 plasma membrane", "go_biological_process": "GO:1903894 regulation of IRE1-mediated unfolded protein response;GO:0044602 protein deadenylylation;GO:0034976 response to endoplasmic reticulum stress;GO:0050908 detection of light stimulus involved in visual perception;GO:0007632 visual behavior", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q8SWV6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q8SWX0-1", "uniprot_id": "ASTRX_DROME", "mass": 20076.0, "length": 167, "protein_name": "Gametocyte-specific factor 1 homolog", "gene_name": "arx", "organism": "Fruit fly", "refseq_name": "asterix", "refseq_ac": "NP_649071", "gene_names_uniprotkb": "arx; CG3893; Gtsf1", "gene_names_refseq": "Arx; BcDNA:LD18018; CG3893; DmGTSF1; Dmel\\CG3893; Gtsf1; arx; gtsf1", "protein_names_uniprotkb": "Gametocyte-specific factor 1 homolog; Protein asterix", "protein_names_refseq": "CG3893-PA; arx-PA; asterix; gametocyte-specific factor 1", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG3893)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "10731132;12537569;12537572;23913921;23913922", "class_list": "", "function": "Acts via the piwi-interacting RNA (piRNA) pathway which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and piwi proteins and governs the methylation and subsequent repression of transposons. Required for repression of transposons and neighboring genes in ovarian somatic and germline cells., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 4, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9VVU3", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000049 tRNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0045892 negative regulation of DNA-templated transcription;GO:0031047 regulatory ncRNA-mediated gene silencing;GO:0048477 oogenesis;GO:0141006 transposable element silencing by piRNA-mediated heterochromatin formation", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q8SWX0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q8SX37-1", "uniprot_id": "CDIPT_DROME", "mass": 25505.0, "length": 224, "protein_name": "CDP-diacylglycerol--inositol 3-phosphatidyltransferase", "gene_name": "Pis", "organism": "Fruit fly", "refseq_name": "phosphatidylinositol synthase, isoform A", "refseq_ac": "NP_573055", "gene_names_uniprotkb": "Pis; CG9245", "gene_names_refseq": "CG9245; Dmel\\CG9245; PIS; Pis; anon-WO02059370.38; dPIS; dPis; dpis", "protein_names_uniprotkb": "CDP-diacylglycerol--inositol 3-phosphatidyltransferase; 2.7.8.11; CDIPT; Phosphatidylinositol synthase", "protein_names_refseq": "CG9245-PA; PI synthase; Phosphatidyl-inositol synthase; Pis-PA; drosophila phosphatidylinositol synthase; phosphatidylinositol synthase, isoform A", "tax_id": 7227, "disease": "chromosome 16p11.2 deletion syndrome, 593-kb (Disease Ontology:DOID:0070515); cancer (Disease Ontology:DOID:162); steatotic liver disease (Disease Ontology:DOID:9452)", "pathway": " (dme:Dmel_CG9245); (R-DME-1483226)", "pathway_count": 2, "publication_count": 6, "publication_id_list": "10731132;12537572;17151285;24603715;24828534;28228250", "class_list": "", "function": "Catalyzes the biosynthesis of phosphatidylinositol (PtdIns) as well as PtdIns:inositol exchange reaction (PubMed:17151285, PubMed:24603715, PubMed:24828534). May thus act to reduce an excessive cellular PtdIns content (By similarity). The exchange activity is due to the reverse reaction of PtdIns synthase and is dependent on CMP, which is tightly bound to the enzyme (By similarity). Required for the regeneration of the signaling molecule phosphatidylinositol 4,5-bisphosphate (PtdInsP2) from phosphatidic acid (PA) and maintenance of its steady supply during signaling, thus playing an essential role during phospholipase C-mediated transduction (PubMed:17151285). This function is essential in photoreceptors for light-activated recycling of PtdInsP2 during phototransduction (PubMed:17151285). As a key enzyme of the phosphoinositide pathway, indirectly involved in the polarized secretion of basal membrane (BM) proteins in follicle epithelial (FE) cells through promoting PtdInsP2 synthesis in the apical and lateral plasma membranes of FE cells (PubMed:24828534). PtdInsP2 controls the localization of Crag and perhaps the localization and expression of strat, both of which are essential for restricting the secretion of BM proteins to the basal surface (PubMed:24828534, PubMed:28228250)., [UniProtKB, PubMed, PubMed, PubMed, UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "F3YDD4;Q8IR29;Q9VXR7", "ec_number_list": "2.7.8.11", "go_molecular_function": "GO:0046872 metal ion binding;GO:0003881 CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0016324 apical plasma membrane;GO:0016328 lateral plasma membrane", "go_biological_process": "GO:0006661 phosphatidylinositol biosynthetic process;GO:0007602 phototransduction;GO:0071711 basement membrane organization", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q8SX37-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q8SX68-1", "uniprot_id": "CT2NL_DROME", "mass": 65422.0, "length": 609, "protein_name": "CTTNBP2 N-terminal-like protein", "gene_name": "Naus", "organism": "Fruit fly", "refseq_name": "nausicaa, isoform B", "refseq_ac": "NP_001286565", "gene_names_uniprotkb": "Naus; CG10915", "gene_names_refseq": "CG10915; Dmel\\CG10915; Naus; naus", "protein_names_uniprotkb": "CTTNBP2 N-terminal-like protein; Protein Nausicaa", "protein_names_refseq": "CG10915-PB; Naus-PB; nausicaa, isoform B; nausicaa", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG10915)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "10731132;12537569;12537572;17372656;31164339", "class_list": "", "function": "Regulates lamellipodial actin dynamics in a Cortactin-dependent manner and is therefore likely involved in controlling actin branch density, actin-retrograde flow rates and lamellipodial protrusion. Functions by slowing the dissociation of Cortactin from Arp2/3 nucleated branches thereby increasing branch nucleation and junction stability (PubMed:31164339). Associates with core striatin-interacting phosphatase and kinase (STRIPAK) complex to form CTTNBP2NL-STRIPAK complexes. STRIPAK complexes have critical roles in protein (de)phosphorylation and are regulators of multiple signaling pathways including Hippo, MAPK, nuclear receptor and cytoskeleton remodeling. Different types of STRIPAK complexes are involved in a variety of biological processes such as cell growth, differentiation, apoptosis, metabolism and immune regulation (By similarity)., [UniProtKB, PubMed, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A0B4LFS3;Q9V8D0", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0015629 actin cytoskeleton;GO:0030027 lamellipodium;GO:0001725 stress fiber;GO:0090443 FAR/SIN/STRIPAK complex", "go_biological_process": "GO:1903119 protein localization to actin cytoskeleton;GO:0035330 regulation of hippo signaling;GO:0061573 actin filament bundle retrograde transport;GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation;GO:2000394 positive regulation of lamellipodium morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q8SX68-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q8SXL2-1", "uniprot_id": "CCHA2_DROME", "mass": 14410.0, "length": 136, "protein_name": "Neuropeptide CCHamide-2", "gene_name": "CCHa2", "organism": "Fruit fly", "refseq_name": "CCHamide-2, isoform B", "refseq_ac": "NP_001189216", "gene_names_uniprotkb": "CCHa2; CG14375", "gene_names_refseq": "BcDNA:RE10132; CCH2a; CCH2; CCHa2; CCHamid2; CCM; CCha2; CG14375; Ccha2; Dm-CCHa2; Dmel\\CG14375; ccha2", "protein_names_uniprotkb": "Neuropeptide CCHamide-2", "protein_names_refseq": "CCHa2-PB; CCHamide 2; CCHamide-2, isoform B; CCHamide2; CG14375-PB; Drm-CCHamide-2", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG14375)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "10731132;12537572;21110953;21214272;23293632;24098432;24850274;26020940;26168160", "class_list": "", "function": "Ligand for the CCHamide-2 receptor CCHa2-R (PubMed:21110953, PubMed:23293632). In one study, shown to be an orexigenic peptide which induces appetite and stimulates food intake, leading to the release of insulin-like peptides which stimulate growth (PubMed:26168160). In another study, shown to be a nutrient-sensitive peptide derived from peripheral tissues which controls growth by directly regulating the production and release of insulin-like peptides (PubMed:26020940)., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9VFV7", "ec_number_list": "", "go_molecular_function": "GO:0005184 neuropeptide hormone activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0007218 neuropeptide signaling pathway", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "Q8SXL2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q8SXU3-1", "uniprot_id": "GMPPA_DROME", "mass": 48110.0, "length": 438, "protein_name": "Mannose-1-phosphate guanylyltransferase regulatory subunit alpha", "gene_name": "Gmppa", "organism": "Fruit fly", "refseq_name": "GDP-mannose pyrophosphorylase A", "refseq_ac": "NP_611051", "gene_names_uniprotkb": "Gmppa; CG8207", "gene_names_refseq": "CG8207; Dmel\\CG8207; Gmppa", "protein_names_uniprotkb": "Mannose-1-phosphate guanylyltransferase regulatory subunit alpha; GDP-mannose pyrophosphorylase A", "protein_names_refseq": "CG8207-PA; GDP-mannose pyrophosphorylase A; Gmppa-PA", "tax_id": 7227, "disease": "alacrima, achalasia, and impaired intellectual development syndrome (Disease Ontology:DOID:0112321)", "pathway": " (dme:Dmel_CG8207); (R-DME-446205)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "10731132;12537569;12537572", "class_list": "", "function": "Regulatory subunit of the GMPPA-GMPPB mannose-1-phosphate guanylyltransferase complex; reduces the catalytic activity of GMPPB when part of the complex. Mediates allosteric feedback inhibition of GMPPB catalytic activity upon binding GDP-alpha-D-mannose. Together with GMPPB regulates GDP-alpha-D-mannose levels., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9V7E1", "ec_number_list": "", "go_molecular_function": "GO:0004857 enzyme inhibitor activity;GO:0140299 molecular sensor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0120508 GDP-mannose pyrophosphorylase complex", "go_biological_process": "GO:0009298 GDP-mannose biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q8SXU3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q8SZA8-1", "uniprot_id": "ADXH2_DROME", "mass": 16407.0, "length": 152, "protein_name": "Adrenodoxin-like protein 2, mitochondrial", "gene_name": "Fdx2", "organism": "Fruit fly", "refseq_name": "ferredoxin 2", "refseq_ac": "NP_647889", "gene_names_uniprotkb": "Fdx2; CG1319; Fdxh2", "gene_names_refseq": "BcDNA:RE08888; BcDNA:RH09920; CG1319; Dmel\\CG1319; Fdx2; Fdxh2", "protein_names_uniprotkb": "Adrenodoxin-like protein 2, mitochondrial; Ferredoxin-2", "protein_names_refseq": "CG1319-PB; Fdx2-PB; ferredoxin 2; ferredoxin", "tax_id": 7227, "disease": "pancreatitis (Disease Ontology:DOID:4989)", "pathway": " (dme:Dmel_CG1319); (R-DME-1362409); (R-DME-2395516); (R-DME-9857492)", "pathway_count": 4, "publication_count": 4, "publication_id_list": "10731132;12537569;12537572;25628335", "class_list": "", "function": "Required for ecdysteroidogenesis in the prothoracic gland which is necessary for larval to pupal transition., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9VZE1", "ec_number_list": "", "go_molecular_function": "GO:0009055 electron transfer activity;GO:0046872 metal ion binding;GO:0051537 2 iron, 2 sulfur cluster binding", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0006694 steroid biosynthetic process;GO:0022900 electron transport chain;GO:0140647 P450-containing electron transport chain;GO:0045998 positive regulation of ecdysteroid biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q8SZA8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q8T0G4-1", "uniprot_id": "CONU_DROME", "mass": 71697.0, "length": 629, "protein_name": "Rho GTPase-activating protein conundrum", "gene_name": "conu", "organism": "Fruit fly", "refseq_name": "conundrum, isoform A", "refseq_ac": "NP_001036454", "gene_names_uniprotkb": "conu; CG17082", "gene_names_refseq": "BcDNA:LD04957; CG17082; CG40286; Conu; Dmel\\CG17082; conu", "protein_names_uniprotkb": "Rho GTPase-activating protein conundrum", "protein_names_refseq": "CG17082-PA; conu-PA; conundrum, isoform A", "tax_id": 7227, "disease": "allergic disease (Disease Ontology:DOID:1205); meningioma (Disease Ontology:DOID:3565); schizophrenia (Disease Ontology:DOID:5419)", "pathway": " (dme:Dmel_CG17082); (R-DME-8980692); (R-DME-9013148)", "pathway_count": 3, "publication_count": 3, "publication_id_list": "10731132;12537572;23468526", "class_list": "", "function": "GTPase-activating protein (GAP) for Rho1; functions with the ERM protein Moe to regulate Rho1 and control proliferation in the developing epithelium. Recruited by Moe to the cell cortex where it negatively regulates Rho1 activity. Can also promote cell proliferation independently of its GAP activity, perhaps by acting with Arf6 to positively regulate Rac1., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q0E9Q3", "ec_number_list": "", "go_molecular_function": "GO:0005096 GTPase activator activity", "go_cellular_component": "GO:0045179 apical cortex;GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0070161 anchoring junction", "go_biological_process": "GO:0007165 signal transduction;GO:0008284 positive regulation of cell population proliferation;GO:0051056 regulation of small GTPase mediated signal transduction;GO:0030833 regulation of actin filament polymerization", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q8T0G4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q8T626-1", "uniprot_id": "DLT_DROME", "mass": 139459.0, "length": 1240, "protein_name": "Protein disks lost", "gene_name": "dlt", "organism": "Fruit fly", "refseq_name": "discs lost", "refseq_ac": "NP_728672", "gene_names_uniprotkb": "dlt; CG32315; VA", "gene_names_refseq": "CG1977; CG32315; DLT; Discs lost; Dlt; Dmel\\CG32315; Van; dlt; dre1; l(3)04276; l(3)62Ba; l(3)dre1", "protein_names_uniprotkb": "Protein disks lost; Codanin 1 homolog; Protein vanaso", "protein_names_refseq": "CG32315-PA; discs lost; dlt-PA; lethal(3)62Ba; vanaso", "tax_id": 7227, "disease": "congenital dyserythropoietic anemia type I (Disease Ontology:DOID:0111396); congenital dyserythropoietic anemia type Ia (Disease Ontology:DOID:0111398); congenital dyserythropoietic anemia (Disease Ontology:DOID:1338)", "pathway": " (dme:Dmel_CG32315)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "10731132;12454076;12537569;12537572;14667407;18327897", "class_list": "", "function": "Regulator of cell proliferation and cell survival of differentiated cells independent of cell division. Essential for imaginal disks formation. Not involved in cell polarity., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q8T627;Q9W084", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0042048 olfactory behavior;GO:0042127 regulation of cell population proliferation;GO:0006325 chromatin organization;GO:0001738 morphogenesis of a polarized epithelium;GO:0007560 imaginal disc morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q8T626-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q94516-1", "uniprot_id": "AT5F1_DROME", "mass": 27358.0, "length": 243, "protein_name": "ATP synthase subunit b, mitochondrial", "gene_name": "ATPsynB", "organism": "Fruit fly", "refseq_name": "ATP synthase, subunit B", "refseq_ac": "NP_524011", "gene_names_uniprotkb": "ATPsynB; ATPsyn-beta; ATPsyn-b; CG8189", "gene_names_refseq": "ATP syn-b; ATP-syn-B; ATPF; ATPsyn-b; ATPsynB; ATPsynbeta; CG8189; Dmel\\CG8189", "protein_names_uniprotkb": "ATP synthase subunit b, mitochondrial; ATPase subunit b; FO-ATP synthase subunit b", "protein_names_refseq": "ATP synthase B chain, mt precursor; ATP synthase B chain; ATP synthase, b; ATP synthase, subunit B; ATPsynB-PA; CG8189-PA; F0/F1 ATP synthase B; Fo-ATP synthase subunit b; broadly-expressed subunit b", "tax_id": 7227, "disease": "clear cell renal cell carcinoma (Disease Ontology:DOID:4467); hepatocellular carcinoma (Disease Ontology:DOID:684)", "pathway": " (dme:Dmel_CG8189); (R-DME-163210); (R-DME-8949613)", "pathway_count": 3, "publication_count": 3, "publication_id_list": "10071211;10731132;12537572", "class_list": "", "function": "Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q53XF7;Q8IQC9;Q9VT43", "ec_number_list": "", "go_molecular_function": "GO:0015078 proton transmembrane transporter activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane;GO:0045259 proton-transporting ATP synthase complex", "go_biological_process": "GO:0015986 proton motive force-driven ATP synthesis;GO:1902600 proton transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q94516-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q94521-1", "uniprot_id": "DNAT_DROME", "mass": 30976.0, "length": 275, "protein_name": "Arylalkylamine N-acetyltransferase 1", "gene_name": "speck", "organism": "Fruit fly", "refseq_name": "speck, isoform A", "refseq_ac": "NP_523839", "gene_names_uniprotkb": "speck; AANAT1; CG3318; Dat; NAT1", "gene_names_refseq": "AA-NAT1; AANAT1; AANATA; AANATB; AANAT; Aanat1; CG3318; DAT1; DAT; Dat1; Dat; DmAANATA; DmAANATB; Dmel\\CG3318; NAT1; aaNAT-1; aaNAT1a; aaNAT1b; aaNAT1; aaNAT; aaNat; speck; sp", "protein_names_uniprotkb": "Arylalkylamine N-acetyltransferase 1; 2.3.1.87; Dopamine N-acetyltransferase", "protein_names_refseq": "CG3318-PA; arylalkylamine N-acetyltransferase 1; arylalkylamine N-acetyltransferase-1; dopamine N acetyltransferase; dopamine N-acetyltransferase; dopamine acetyltransferase; speck, isoform A; speck-PA", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG3318)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10710313;10731132;12537569;12537572;22716280;25406072;32709620;32955431;7498465;8901578;9703021", "class_list": "", "function": "Catalyzes N-acetylation of tryptamine, tyramine, dopamine, serotonin and octopamine (PubMed:25406072, PubMed:7498465, PubMed:8901578). In astrocytes, regulates sleep homeostasis by limiting the accumulation of serotonin and dopamine in the brain upon sleep deprivation (PubMed:10710313, PubMed:32955431). Is not essential for sclerotization (PubMed:9703021)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 12, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q8MKK2;Q9TWF1", "ec_number_list": "2.3.1.87;2.3.2.-", "go_molecular_function": "GO:0004060 arylamine N-acetyltransferase activity;GO:0004059 aralkylamine N-acetyltransferase activity;GO:0008080 N-acetyltransferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0045187 regulation of circadian sleep/wake cycle, sleep;GO:0030431 sleep;GO:0042420 dopamine catabolic process;GO:0006584 catecholamine metabolic process;GO:0030187 melatonin biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q94521-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q94524-1", "uniprot_id": "DYLT_DROME", "mass": 12479.0, "length": 111, "protein_name": "Dynein light chain Tctex-type", "gene_name": "Dlc90F", "organism": "Fruit fly", "refseq_name": "dynein light chain 90F", "refseq_ac": "NP_477356", "gene_names_uniprotkb": "Dlc90F; CG12363; Tctex", "gene_names_refseq": "CG12363; Dlc90F; Dmel\\CG12363; Dynein; TcTex-1; Tctex-1; Tctex1; Tctex; bs35g12.y1; dlc90F; dtctex-1; l(3)04091; tctex-1; tctex", "protein_names_uniprotkb": "Dynein light chain Tctex-type; TCTEX-1 protein homolog", "protein_names_refseq": "CG12363-PA; Dlc90F-PA; dynein light chain 90F; dynein light chain; tctex-1", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG12363); (R-DME-6798695)", "pathway_count": 2, "publication_count": 5, "publication_id_list": "10071211;10731132;11405626;12537572;15090621", "class_list": "", "function": "Acts as one of several non-catalytic accessory components of the cytoplasmic dynein complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. Required for spermatid differentiation. Is not required for polarized transport in rhabdomere development and appears to be a non-essential component of the cytoplasmic dynein complex., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9VE95", "ec_number_list": "", "go_molecular_function": "GO:0042802 identical protein binding;GO:0042803 protein homodimerization activity;GO:0097718 disordered domain specific binding;GO:0051959 dynein light intermediate chain binding;GO:0045505 dynein intermediate chain binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005874 microtubule;GO:1904115 axon cytoplasm;GO:0005868 cytoplasmic dynein complex;GO:0032991 protein-containing complex", "go_biological_process": "GO:0008090 retrograde axonal transport;GO:0000278 mitotic cell cycle;GO:0007286 spermatid development;GO:0007018 microtubule-based movement", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q94524-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q94546-1", "uniprot_id": "ATU_DROME", "mass": 77422.0, "length": 725, "protein_name": "Another transcription unit protein", "gene_name": "Atu", "organism": "Fruit fly", "refseq_name": "another transcription unit", "refseq_ac": "NP_524240", "gene_names_uniprotkb": "Atu; CG1433", "gene_names_refseq": "Atu; CG1433; Dmel\\CG1433; Leo1; atu; dLeo1; l(3)s1938", "protein_names_uniprotkb": "Another transcription unit protein", "protein_names_refseq": "Atu-PA; CG1433-PA; another transcription unit", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG1433); (R-DME-112382); (R-DME-201722); (R-DME-674695); (R-DME-75955); (R-DME-8866654); (R-DME-9943411)", "pathway_count": 7, "publication_count": 6, "publication_id_list": "10731132;12537569;12537572;17372656;18327897;9475742", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 20, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9VNE6", "ec_number_list": "", "go_molecular_function": "GO:1990269 RNA polymerase II C-terminal domain phosphoserine binding", "go_cellular_component": "GO:0005634 nucleus;GO:0016593 Cdc73/Paf1 complex", "go_biological_process": "GO:0006368 transcription elongation by RNA polymerase II;GO:0032968 positive regulation of transcription elongation by RNA polymerase II;GO:0035206 regulation of hemocyte proliferation", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q94546-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q95RA9-1", "uniprot_id": "GILT1_DROME", "mass": 27692.0, "length": 250, "protein_name": "GILT-like protein 1", "gene_name": "GILT1", "organism": "Fruit fly", "refseq_name": "Gamma-interferon-inducible lysosomal thiol reductase 1", "refseq_ac": "NP_650287", "gene_names_uniprotkb": "GILT1; CG9796", "gene_names_refseq": "CG9796; Dmel\\CG9796; GILT1; GILT", "protein_names_uniprotkb": "GILT-like protein 1", "protein_names_refseq": "CG9796-PA; GILT1-PA; Gamma-interferon-inducible lysosomal thiol reductase 1; Gamma-interferon-inducible lysosomal thiol reductase", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG9796); (R-DME-2132295)", "pathway_count": 2, "publication_count": 6, "publication_id_list": "10731132;12537572;24491521;28953965;33925313;40245499", "class_list": "", "function": "Involved in the immune response to bacterial infection., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 2, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 2, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 2, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "Q9VFV4", "ec_number_list": "", "go_molecular_function": "GO:0016491 oxidoreductase activity;GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor", "go_cellular_component": "GO:0005576 extracellular region;GO:0005886 plasma membrane", "go_biological_process": "GO:1900426 positive regulation of defense response to bacterium;GO:0002376 immune system process", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "Q95RA9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q95RN0-1", "uniprot_id": "F172A_DROME", "mass": 36561.0, "length": 325, "protein_name": "FAM172 family protein homolog CG10038", "gene_name": "CG10038", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform A", "refseq_ac": "NP_650176", "gene_names_uniprotkb": "CG10038", "gene_names_refseq": "CG10038; Dmel\\CG10038", "protein_names_uniprotkb": "FAM172 family protein homolog CG10038", "protein_names_refseq": "CG10038-PA; uncharacterized protein, isoform A", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG10038)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "10731132;12537569;12537572", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q86BS1;Q9VGA6", "ec_number_list": "", "go_molecular_function": "GO:0017171 serine hydrolase activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0031048 regulatory ncRNA-mediated heterochromatin formation", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q95RN0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q95RV2-1", "uniprot_id": "CAV_DROME", "mass": 39408.0, "length": 345, "protein_name": "Telomere-binding protein cav", "gene_name": "cav", "organism": "Fruit fly", "refseq_name": "caravaggio, isoform A", "refseq_ac": "NP_524477", "gene_names_uniprotkb": "cav; CG6219; Hoap; IG5; anon fe 1G5; anon1G5", "gene_names_refseq": "1G5; Anon1G5; CG6219; Caravaggio; Cav/HOAP; Cav; Dmel\\CG6219; HOAP; Hoap; anon fe 1G5; anon-EST:fe1G5; anon1G5; cav/HOAP; cav; hoap; p55", "protein_names_uniprotkb": "Telomere-binding protein cav; Anonymous fast evolving 1G5; HOAP p55; HP1/ORC-associated protein; Protein caravaggio", "protein_names_refseq": "CG6219-PA; HP1 and Orc-associated protein; HP1-ORC associated protein; HP1/ORC-associated protein; anon-fast-evolving-1G5; anonymous fast evolving gene IG5; caravaggio, isoform A; cav-PA; drosophila anonymous fast evolving 1G5", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG6219)", "pathway_count": 1, "publication_count": 16, "publication_id_list": "10581279;10731132;11408576;12510197;12537569;12537572;12826664;18984573;19181850;19190990;19240120;20057353;20679394;26110638;27835648;9275195", "class_list": "", "function": "Part of the HipHop-HOAP complex that recruits the MTV complex to form the terminin telomere-capping complex, which binds to chromosome ends in a sequence-independent manner and prevents telomere fusion (PubMed:11408576, PubMed:12510197, PubMed:12826664, PubMed:19181850, PubMed:19190990, PubMed:20057353). Telomere capping is independent of the origin recognition complex (ORC) (PubMed:12510197)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "B6UW60;B6UW70;B6UW72;B6UW76;B6UW79;B6UW88;O16046;O18360;O18361;O18362;O18667;O18675;Q7KLS0;Q7KQE4;Q7KQE8;Q86BN7;Q9TVU4;Q9U4P0;Q9VCB3", "ec_number_list": "", "go_molecular_function": "GO:0042162 telomeric DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0000775 chromosome, centromeric region;GO:0000781 chromosome, telomeric region;GO:0000782 telomere cap complex", "go_biological_process": "GO:0000723 telomere maintenance;GO:0016233 telomere capping;GO:0031848 protection from non-homologous end joining at telomere", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "Q95RV2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q95SK3-1", "uniprot_id": "CK5P3_DROME", "mass": 57742.0, "length": 509, "protein_name": "CDK5RAP3 protein homolog", "gene_name": "CG30291", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": "NP_726016", "gene_names_uniprotkb": "CG30291", "gene_names_refseq": "CG30291; CG3282; Dmel\\CG30291", "protein_names_uniprotkb": "CDK5RAP3 protein homolog", "protein_names_refseq": "CG30291-PA; uncharacterized protein", "tax_id": 7227, "disease": "early infantile epileptic encephalopathy (Disease Ontology:DOID:0050709)", "pathway": " (dme:Dmel_CG30291)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "10731132;12537569;12537572", "class_list": "", "function": "Substrate adapter of E3 ligase complexes mediating ufmylation, the covalent attachment of the ubiquitin-like modifier UFM1 to substrate proteins, and which is involved in various processes, such as ribosome recycling and reticulophagy (also called ER-phagy)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:1990756 ubiquitin-like ligase-substrate adaptor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0012505 endomembrane system", "go_biological_process": "GO:0007346 regulation of mitotic cell cycle;GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0030968 endoplasmic reticulum unfolded protein response", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q95SK3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q95T12-1", "uniprot_id": "FLOWR_DROME", "mass": 20620.0, "length": 194, "protein_name": "Calcium channel flower", "gene_name": "fwe", "organism": "Fruit fly", "refseq_name": "flower, isoform A", "refseq_ac": "NP_648804", "gene_names_uniprotkb": "fwe; CG6151; flower", "gene_names_refseq": "CG6151; Dmel\\CG6151; Fwe; anon-WO0118547.242; dFwe; drFlower; fwe", "protein_names_uniprotkb": "Calcium channel flower; 3L5", "protein_names_refseq": "CG6151-PA; flower, isoform A; flower; fwe-PA", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG6151)", "pathway_count": 1, "publication_count": 15, "publication_id_list": "10731132;12537569;12537572;19737521;20627080;20951347;23810538;25601460;25754635;28011160;28414717;29288152;30590040;33300871;35301437", "class_list": "", "function": "Functions with the other flower isoforms to produce tissue-specific fitness fingerprints that identify unfit cells for cell selection processes during development, regeneration, and to maintain tissue health (PubMed:20627080, PubMed:25601460, PubMed:25754635, PubMed:30590040). During cell competition in certain tissues, marks suboptimal or damaged cells as 'loser' cells (PubMed:20627080, PubMed:25601460, PubMed:25754635, PubMed:30590040). In cells of the wing imaginal disk and damaged or dysfunctional neurons in the adult optic lobe, this isoform displays low to no expression in healthy/normal cells but is up-regulated in cells with decreased fitness or damage-affected neurons (PubMed:20627080, PubMed:25754635, PubMed:30590040). During cell competition, if levels of this isoform in unfit cells is higher than in the surrounding neighboring cells, the suboptimal cells are recognized as 'loser' cells, and undergo elimination via apoptosis to be replaced by the surrounding healthy/undamaged 'winner' cell population (PubMed:20627080, PubMed:25754635, PubMed:30590040). In the developing pupal retina, also required for the recognition and elimination of postmitotic neurons, including supernumerary photoreceptor neurons that form at the periphery of the retina and are contained within incomplete ommatidia units (PubMed:23810538). Activity at the peripheral retina is induced by the wg signaling pathway but, once activated, it promotes apoptosis of supernumerary photoreceptor neurons independently of wg signaling and snail function (PubMed:23810538)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]; Transmembrane protein which mediates synaptic endocytosis, fitness-based cell culling, neuronal culling, morphogen gradient scaling, and calcium transport (PubMed:20627080, PubMed:23810538, PubMed:25601460, PubMed:28011160, PubMed:33300871, PubMed:35301437). Regulates synaptic endocytosis and hence couples exo- with endocytosis (PubMed:19737521, PubMed:28414717, PubMed:29288152, PubMed:33300871). Controls two major modes of synaptic vesicle (SV) endocytosis in the synaptic boutons of neuromuscular junctions (NMJs); Ca(2+) channel-independent Clathrin-mediated endocytosis (CME) in response to mild stimulation, and Ca(2+) channel-dependent activity-dependent bulk endocytosis (ADBE) in response to strong stimulation (PubMed:28414717, PubMed:33300871). Functions in ADBE and subsequent SV reformation from bulk endosomes by initiating Ca(2+) channel-dependent phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) compartmentalization in synaptic boutons (PubMed:28414717, PubMed:33300871). There it acts at the periactive zone to provide the low Ca(2+) levels required to initiate Calcineurin activation and upregulate PtdIns(4,5)P2 (PubMed:33300871). Conversely PtdIns(4,5)P2 enhances fwe Ca(2+) channel-activity, establishing a positive feedback loop that induces PtdIns(4,5)P2 microdomain at the periactive zone (PubMed:33300871). These microdomains trigger bulk membrane invagination (i.e. ADBE) by triggering actin polymerization while also promoting localization of fwe to bulk endosomes, thereby removing the ADBE trigger to reduce endocytosis and prevent excess membrane uptake (PubMed:33300871). PtdIns(4,5)P2 then promotes SV reformation from the bulk endosomes, to coordinate ADBE and subsequent SV reformation (PubMed:33300871). Different combinations of the flower isoforms at the cell membrane are also required for the identification and elimination of suboptimal or supernumerary cells during development, regeneration, and adulthood (PubMed:20627080, PubMed:20951347, PubMed:23810538, PubMed:25601460, PubMed:28011160, PubMed:30590040). Required for the recognition and elimination of unfit cells in the developing wing during cell competition (PubMed:20627080). Also required for efficient identification and elimination of injured, damaged and/or dysfunctional neurons during regeneration of the adult brain (PubMed:25754635, PubMed:30590040). In the developing pupal retina, mediates the elimination of unwanted postmitotic neurons, including supernumerary photoreceptor neurons that form at the periphery of the retina and are contained within incomplete ommatidia units (PubMed:23810538). Downstream of the flower fitness fingerprints, cells identified as unwanted or unfit are eliminated via apoptosis through the expression of ahuizotl (azot) (PubMed:25601460, PubMed:30590040). However, the cells marked for elimination by the flower isoforms only undergo apoptosis if additional thresholds are met; (1) their neighboring fit/healthy cells express different levels of the fwe isoforms, and (2) the levels of the protective signal SPARC expressed by the loser or unwanted cells are unable to inhibit caspase activation (PubMed:20627080, PubMed:20951347, PubMed:23810538). These additional thresholds for flower-mediated apoptosis, allows useful cells to recover from transient and limited stress before they are unnecessarily eliminated (PubMed:20951347). Functions with dally and magu in a mechanism of scaling, which utilises apoptosis to ensure that the dpp morphogen gradient, which mediates organ growth, remains proportional to the size of the growing wing (PubMed:35301437). In this mechanism, fwe represses dally- and Magu-dependent activity in expanding the gradient, and dally/Magu inhibits fwe-dependent apoptosis to keep cell death rate low (PubMed:35301437). When the levels of these different proteins are optimally regulated the gradient correctly scales with organ growth but when this fails, fwe-mediated apoptosis is activated to trim the developing tissue to match the correct size of the gradient (PubMed:35301437)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 7, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q8IQM8;Q9VUU2", "ec_number_list": "", "go_molecular_function": "GO:0005262 calcium channel activity;GO:0042802 identical protein binding", "go_cellular_component": "GO:0005768 endosome;GO:0005886 plasma membrane;GO:0030672 synaptic vesicle membrane;GO:0042734 presynaptic membrane", "go_biological_process": "GO:0006816 calcium ion transport;GO:0016192 vesicle-mediated transport;GO:0042981 regulation of apoptotic process;GO:0043525 positive regulation of neuron apoptotic process;GO:0070588 calcium ion transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "Q95T12-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q95TJ9-1", "uniprot_id": "CYCG_DROME", "mass": 62791.0, "length": 566, "protein_name": "Cyclin G", "gene_name": "CycG", "organism": "Fruit fly", "refseq_name": "cyclin G, isoform F", "refseq_ac": "NP_001263146", "gene_names_uniprotkb": "CycG; CG11525", "gene_names_refseq": "CG 11525; CG11525; CycG; Dmel\\CG11525; anon-EST:Liang-1.25; anon-EST:Liang-2.24; chr3R:27424276..27424475; clone 1.25; clone 2.24; cycG; dCycG; i205; i261", "protein_names_uniprotkb": "Cyclin G", "protein_names_refseq": "CG11525-PF; CycG-PF; cyclin G, isoform F; cyclin G1; cyclin G", "tax_id": 7227, "disease": "ovarian serous carcinoma (Disease Ontology:DOID:0050933); traumatic brain injury (Disease Ontology:DOID:0081292); Alzheimer's disease (Disease Ontology:DOID:10652); urinary bladder cancer (Disease Ontology:DOID:11054); sarcoma (Disease Ontology:DOID:1115); Human papillomavirus infectious disease (Disease Ontology:DOID:11166); head and neck cancer (Disease Ontology:DOID:11934); leiomyoma (Disease Ontology:DOID:127); lung cancer (Disease Ontology:DOID:1324); breast cancer (Disease Ontology:DOID:1612); pancreatic cancer (Disease Ontology:DOID:1793); rectum cancer (Disease Ontology:DOID:1993); ovary epithelial cancer (Disease Ontology:DOID:2152); colon cancer (Disease Ontology:DOID:219); ovarian cancer (Disease Ontology:DOID:2394); localized osteosarcoma (Disease Ontology:DOID:3356); ovarian carcinoma (Disease Ontology:DOID:4001); hepatocellular carcinoma (Disease Ontology:DOID:684); muscular atrophy (Disease Ontology:DOID:767); cervix uteri carcinoma in situ (Disease Ontology:DOID:8991)", "pathway": " (dme:Dmel_CG11525)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537569;12537572;18286205;18667003;21311225;21998598;22976300;23121330;25995770;26274446", "class_list": "", "function": "Cyclin with roles in multiple processes including transcription, meiotic recombination repair, cell cycle regulation, and promotion of normal growth and metabolism (PubMed:18286205, PubMed:18667003, PubMed:21311225, PubMed:22976300, PubMed:25995770, PubMed:26274446). Binds to the promoter region of the homeobox gene Abd-B and is involved in maintaining Abd-B expression in the pupal epithelium (PubMed:18286205, PubMed:18667003). Involved in the transcriptional repression of the homeotic genes Scr and Ubx (PubMed:25995770). Plays a role in meiotic recombination repair of DNA double-strand breaks which ensures efficient translation of grk and promotes grk activity in the oocyte, leading to oocyte dorso-ventral axis formation following secretion of grk from the oocyte and its binding to Egfr in the directly overlying follicle cells (PubMed:22976300, PubMed:23121330). Negatively regulates the binding of serine/threonine-protein kinase Akt1 to the protein phosphatase 2A subunit wdb, promoting normal growth and metabolism (PubMed:26274446). Required for the formation of bilateral symmetry (PubMed:21998598). Negatively regulates cell cycle progression by preventing G1 to S transition and retarding S-phase progression (PubMed:21311225)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 20, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0004864 protein phosphatase inhibitor activity;GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0000307 cyclin-dependent protein kinase holoenzyme complex;GO:0005700 polytene chromosome", "go_biological_process": "GO:0060429 epithelium development;GO:0006351 DNA-templated transcription;GO:0051301 cell division;GO:0051897 positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction;GO:0006302 double-strand break repair", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q95TJ9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q95TN4-1", "uniprot_id": "COG4_DROME", "mass": 87715.0, "length": 776, "protein_name": "Conserved oligomeric Golgi complex subunit 4", "gene_name": "Cog4", "organism": "Fruit fly", "refseq_name": "component of oligomeric golgi complex 4", "refseq_ac": "NP_609413", "gene_names_uniprotkb": "Cog4; CG7456", "gene_names_refseq": "CG7456; Cog4; Dmel\\CG7456", "protein_names_uniprotkb": "Conserved oligomeric Golgi complex subunit 4; COG complex subunit 4; Component of oligomeric Golgi complex 4", "protein_names_refseq": "CG7456-PA; Cog4-PA; component of oligomeric golgi complex 4", "tax_id": 7227, "disease": "congenital disorder of glycosylation type IIj (Disease Ontology:DOID:0070262); Saul-Wilson syndrome (Disease Ontology:DOID:0111673)", "pathway": " (dme:Dmel_CG7456); (R-DME-6807878); (R-DME-6811438); (R-DME-6811440)", "pathway_count": 4, "publication_count": 4, "publication_id_list": "10731132;12537569;12537572;18327897", "class_list": "", "function": "Required for normal Golgi function., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9VKU6", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0017119 Golgi transport complex", "go_biological_process": "GO:0015031 protein transport;GO:0006890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum;GO:0007030 Golgi organization;GO:0000301 retrograde transport, vesicle recycling within Golgi;GO:0006891 intra-Golgi vesicle-mediated transport", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q95TN4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q95U54-1", "uniprot_id": "MMS19_DROME", "mass": 107048.0, "length": 959, "protein_name": "MMS19 nucleotide excision repair protein", "gene_name": "Mms19", "organism": "Fruit fly", "refseq_name": "Mms19", "refseq_ac": "NP_649519", "gene_names_uniprotkb": "Mms19; CG12005; NEST:bs07f08", "gene_names_refseq": "CG12005; Dmel\\CG12005; MMS19; Mms19; NEST:bs07f08; dMMS19; mms19", "protein_names_uniprotkb": "MMS19 nucleotide excision repair protein", "protein_names_refseq": "CG12005-PB; Mms19-PB; Mms19", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG12005)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "10731132;11328871;12537569;12537572;29361561;33211700", "class_list": "", "function": "Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity (By similarity). In the CIA complex, MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins (By similarity). Essential for diploid cell cycles, organ growth and development (PubMed:29361561). Regulates mitosis by binding to Xpd and thereby competing with the Xpd-mediated repression on the Cdk-activating kinase (CAK) complex (PubMed:29361561). Regulates the centrosomal localization of the MT regulator tacc, a downstream target of aurA kinase (PubMed:33211700). Binds to microtubules (MT) (PubMed:33211700). Regulates spindle and astral MT growth, MT stability and bundling (PubMed:33211700). In neuroblasts, necessary for timely and coordinated spindle assembly and orientation which is necessary for mitotic progression (PubMed:33211700). In young embryos, the maternal protein is important for progression through mitosis (PubMed:29361561)., [UniProtKB, PubMed, PubMed, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q968K4", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0097361 cytosolic [4Fe-4S] assembly targeting complex;GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005819 spindle;GO:0005829 cytosol", "go_biological_process": "GO:0006281 DNA repair;GO:0007059 chromosome segregation;GO:0051301 cell division;GO:0031116 positive regulation of microtubule polymerization;GO:0051604 protein maturation", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q95U54-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q960W6-1", "uniprot_id": "FACR3_DROME", "mass": 58466.0, "length": 516, "protein_name": "Putative fatty acyl-CoA reductase CG8306", "gene_name": "CG8306", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": "NP_611140", "gene_names_uniprotkb": "CG8306", "gene_names_refseq": "CG8306; Dmel\\CG8306", "protein_names_uniprotkb": "Putative fatty acyl-CoA reductase CG8306; 1.2.1.84", "protein_names_refseq": "CG8306-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG8306); (R-DME-9640463)", "pathway_count": 2, "publication_count": 4, "publication_id_list": "10731132;12537569;12537572;40245499", "class_list": "", "function": "Catalyzes the reduction of C16 or C18 fatty acyl-CoA to fatty alcohols., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 2, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 2, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 2, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "Q9V7R8", "ec_number_list": "1.2.1.84", "go_molecular_function": "GO:0080019 alcohol-forming very long-chain fatty acyl-CoA reductase activity;GO:0102965 alcohol-forming long-chain fatty acyl-CoA reductase activity", "go_cellular_component": "GO:0005777 peroxisome;GO:0016020 membrane;GO:0012505 endomembrane system", "go_biological_process": "GO:0035336 long-chain fatty-acyl-CoA metabolic process;GO:0010025 wax biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q960W6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q961G1-1", "uniprot_id": "COG3_DROME", "mass": 101240.0, "length": 905, "protein_name": "Conserved oligomeric Golgi complex subunit 3", "gene_name": "Cog3", "organism": "Fruit fly", "refseq_name": "component of oligomeric golgi complex 3", "refseq_ac": "NP_608779", "gene_names_uniprotkb": "Cog3; CG3248", "gene_names_refseq": "CG 3248; CG3248; COG3; Cog3; Dmel\\CG3248; SEC34; dCOG3", "protein_names_uniprotkb": "Conserved oligomeric Golgi complex subunit 3; COG complex subunit 3; Component of oligomeric Golgi complex 3", "protein_names_refseq": "CG3248-PA; Cog3-PA; component of oligomeric golgi complex 3", "tax_id": 7227, "disease": "congenital disorder of glycosylation type IIbb (Disease Ontology:DOID:0051047)", "pathway": " (dme:Dmel_CG3248); (R-DME-6807878); (R-DME-6811438); (R-DME-6811440)", "pathway_count": 4, "publication_count": 4, "publication_id_list": "10731132;12537569;12537572;18327897", "class_list": "", "function": "Involved in ER-Golgi transport., [UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "Q9VQQ8", "ec_number_list": "", "go_molecular_function": "GO:0140312 cargo adaptor activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005801 cis-Golgi network;GO:0017119 Golgi transport complex", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0007030 Golgi organization;GO:0000301 retrograde transport, vesicle recycling within Golgi;GO:0006891 intra-Golgi vesicle-mediated transport", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q961G1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q961J5-1", "uniprot_id": "BALAT_DROME", "mass": 67905.0, "length": 604, "protein_name": "Beta-alanine transporter", "gene_name": "Balat", "organism": "Fruit fly", "refseq_name": "Beta-alanine transporter", "refseq_ac": "NP_610823", "gene_names_uniprotkb": "Balat; CG3790", "gene_names_refseq": "BalaT; Balat; CG3790; CT; Dmel\\CG3790; balat", "protein_names_uniprotkb": "Beta-alanine transporter; BalaT", "protein_names_refseq": "Balat-PA; Beta-alanine transporter; CG3790-PA; carnitine transporter", "tax_id": 7227, "disease": "kidney failure (Disease Ontology:DOID:1074); extrahepatic cholestasis (Disease Ontology:DOID:13619); intrahepatic cholestasis (Disease Ontology:DOID:1852); hyperuricemia (Disease Ontology:DOID:1920); asthma (Disease Ontology:DOID:2841); acute kidney failure (Disease Ontology:DOID:3021); rheumatoid arthritis (Disease Ontology:DOID:7148); end stage renal disease (Disease Ontology:DOID:783)", "pathway": " (dme:Dmel_CG3790); (R-DME-112311); (R-DME-181430); (R-DME-196807); (R-DME-200425); (R-DME-2161517); (R-DME-442660); (R-DME-549127); (R-DME-561048); (R-DME-917937); (R-DME-9749641); (R-DME-9793528)", "pathway_count": 12, "publication_count": 4, "publication_id_list": "10731132;12537569;12537572;28806173", "class_list": "", "function": "Beta-alanine transporter required for the uptake of beta-alanine by the glia (PubMed:28806173). Required for the recycling process of the neurotransmitter histamine in photoreceptor neurons of the compound eye and therefore for photoreceptor synaptic transmission (PubMed:28806173). Following histamine release from photoreceptors and its uptake by glia, histamine is conjugated to beta-alanine by e/Ebony to form the inactive metabolite, carcinine (PubMed:28806173)., [UniProtKB, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 8, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "Q9V6H5", "ec_number_list": "", "go_molecular_function": "GO:0001761 beta-alanine transmembrane transporter activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0001694 histamine biosynthetic process;GO:0001762 beta-alanine transport", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q961J5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9GU68-1", "uniprot_id": "IF5A_DROME", "mass": 17591.0, "length": 159, "protein_name": "Eukaryotic translation initiation factor 5A", "gene_name": "eEF5", "organism": "Fruit fly", "refseq_name": "eukaryotic translation elongation factor 5, isoform A", "refseq_ac": "NP_611878", "gene_names_uniprotkb": "eEF5; CG3186", "gene_names_refseq": "1296; CG3186; Dmel\\CG3186; anon-EST:fe2H10; chr2R:19566878..19566998; eEF5; eIF-5A; eIF5A; eIF5a; l(2)01296; l(2)SH2 2271; l(2)SH2271", "protein_names_uniprotkb": "Eukaryotic translation initiation factor 5A; eIF-5A", "protein_names_refseq": "CG3186-PA; anon-fast-evolving-2H10; eEF5-PA; eIF-5A; eukaryotic initiation factor 5A; eukaryotic translation elongation factor 5, isoform A; eukaryotic translation factor 5A; lethal (2) SH2271", "tax_id": 7227, "disease": "pancreatic ductal adenocarcinoma (Disease Ontology:DOID:3498); pulmonary hypertension (Disease Ontology:DOID:6432); colorectal cancer (Disease Ontology:DOID:9256)", "pathway": " (dme:Dmel_CG3186); (R-DME-204626)", "pathway_count": 2, "publication_count": 4, "publication_id_list": "10731132;12537569;12537572;19546244", "class_list": "", "function": "Translation factor that promotes translation elongation and termination, particularly upon ribosome stalling at specific amino acid sequence contexts. Binds between the exit (E) and peptidyl (P) site of the ribosome and promotes rescue of stalled ribosome: specifically required for efficient translation of polyproline-containing peptides as well as other motifs that stall the ribosome. Acts as a ribosome quality control (RQC) cofactor by joining the RQC complex to facilitate peptidyl transfer during CAT tailing step (By similarity). Functions as a regulator of autophagy (PubMed:19546244)., [UniProtKB, PubMed, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A1B2AK02;Q2MGM4;Q9NDH0;Q9W1C0", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding;GO:0003746 translation elongation factor activity;GO:0043022 ribosome binding", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0045901 positive regulation of translational elongation;GO:0007618 mating;GO:0006414 translational elongation;GO:0002181 cytoplasmic translation", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q9GU68-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9NB71-1", "uniprot_id": "HIW_DROME", "mass": 565631.0, "length": 5233, "protein_name": "E3 ubiquitin-protein ligase highwire", "gene_name": "hiw", "organism": "Fruit fly", "refseq_name": "highwire, isoform B", "refseq_ac": "NP_001285258", "gene_names_uniprotkb": "hiw; CG32592; CG9041; CG9049; Dmel\\CG32592; Dmel_CG32592; HIW; Hiw", "gene_names_refseq": "CG32592; CG9041; CG9049; Dmel\\CG32592; HIW; Hiw; hiw", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase highwire; 2.3.2.33; Protein pam/highwire/rpm-1", "protein_names_refseq": "CG32592-PB; highwire, isoform B; highwire; hiw-PB", "tax_id": 7227, "disease": "prostate cancer (Disease Ontology:DOID:10283); colon cancer (Disease Ontology:DOID:219); thyroid gland carcinoma (Disease Ontology:DOID:3963); brain disease (Disease Ontology:DOID:936)", "pathway": " (dme:Dmel_CG32592)", "pathway_count": 1, "publication_count": 16, "publication_id_list": "10731132;10839352;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;17697379;18327897;21874015;25589440;26109356;26109357", "class_list": "", "function": "Atypical E3 ubiquitin-protein ligase which specifically mediates ubiquitination of threonine and serine residues on target proteins, instead of ubiquitinating lysine residues (By similarity). Shows esterification activity towards both threonine and serine, with a preference for threonine, and acts via two essential catalytic cysteine residues that relay ubiquitin to its substrate via thioester intermediates (By similarity). Required in the presynaptic motoneuron to down-regulate the levels of wnd and restrain synaptic terminal growth at the neuromuscular junction (NMJ) together with Rae1 and Fsn (PubMed:10839352, PubMed:17697379, PubMed:21874015)., [UniProtKB, UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 9, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "Q8MZ36;Q9VXZ5", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005886 plasma membrane;GO:0030424 axon;GO:0045202 synapse;GO:0031410 cytoplasmic vesicle", "go_biological_process": "GO:2000331 regulation of terminal button organization;GO:0006351 DNA-templated transcription;GO:0010629 negative regulation of gene expression;GO:0050808 synapse organization;GO:0006914 autophagy", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "Q9NB71-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9NFT7-1", "uniprot_id": "HXK2_DROME", "mass": 53486.0, "length": 486, "protein_name": "Hexokinase-2", "gene_name": "Hex-T", "organism": "Fruit fly", "refseq_name": "hexokinase testis 2", "refseq_ac": "NP_733151", "gene_names_uniprotkb": "Hex-T; CG32849; DHK-453; Hex-t2; Hex", "gene_names_refseq": "CG32849; CG5443; Dmel\\CG32849; HK; Hex-T2; Hex-t2; Hex; anon-WO0140519.203", "protein_names_uniprotkb": "Hexokinase-2; 2.7.1.1; Hexokinase testis", "protein_names_refseq": "CG32849-PA; Hex-t2-PA; hexokinase testis 2; hexokinase", "tax_id": 7227, "disease": "maturity-onset diabetes of the young (Disease Ontology:DOID:0050524); congenital nonspherocytic hemolytic anemia 5 (Disease Ontology:DOID:0051006); permanent neonatal diabetes mellitus (Disease Ontology:DOID:0060639); retinitis pigmentosa 92 (Disease Ontology:DOID:0061107); retinitis pigmentosa 79 (Disease Ontology:DOID:0061108); familial hyperinsulinemic hypoglycemia 3 (Disease Ontology:DOID:0070216); Charcot-Marie-Tooth disease type 4G (Disease Ontology:DOID:0110196); maturity-onset diabetes of the young type 2 (Disease Ontology:DOID:0111100); retinitis pigmentosa (Disease Ontology:DOID:10584); hypertension (Disease Ontology:DOID:10763); sickle cell anemia (Disease Ontology:DOID:10923); urinary bladder cancer (Disease Ontology:DOID:11054); gestational diabetes (Disease Ontology:DOID:11714); neonatal diabetes mellitus (Disease Ontology:DOID:11717); hyperinsulinemic hypoglycemia (Disease Ontology:DOID:13317); hyperinsulinism (Disease Ontology:DOID:2018); anemia (Disease Ontology:DOID:2355); congenital nonspherocytic hemolytic anemia (Disease Ontology:DOID:2861); coronary artery disease (Disease Ontology:DOID:3393); hyperglycemia (Disease Ontology:DOID:4195); pulmonary hypertension (Disease Ontology:DOID:6432); colorectal cancer (Disease Ontology:DOID:9256); diabetes mellitus (Disease Ontology:DOID:9351); type 2 diabetes mellitus (Disease Ontology:DOID:9352); steatotic liver disease (Disease Ontology:DOID:9452); multiple myeloma (Disease Ontology:DOID:9538); acute lymphoblastic leukemia (Disease Ontology:DOID:9952); obesity (Disease Ontology:DOID:9970); hypoglycemia (Disease Ontology:DOID:9993)", "pathway": " (dme:Dmel_CG32849); (R-DME-170822); (R-DME-446205); (R-DME-6798695); (R-DME-70171)", "pathway_count": 5, "publication_count": 4, "publication_id_list": "10731132;11063694;12537569;12537572", "class_list": "", "function": "Catalyzes the phosphorylation of various hexoses to hexose 6-phosphate., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 29, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q95U08;Q9NFT8;Q9VBF1", "ec_number_list": "2.4.1.186;5.4.2.7;5.4.2.-;3.2.1.31;1.1.1.42;2.4.2.1;2.7.11.24;2.7.1.40;4.1.2.13;2.7.4.6;2.4.2.7;3.6.5.-;1.11.1.6;5.3.1.9;2.7.1.11;1.1.1.205;3.4.22.-;3.6.4.12;3.6.4.6;1.16.3.1;2.7.1.35;2.3.2.5;3.4.24.-;2.3.2.27;2.7.1.1;5.2.1.8;3.4.19.-;1.11.1.24;5.6.1.5;5.4.2.11;5.4.2.4;3.2.1.23;3.6.1.5;3.6.4.13;3.3.2.6;3.5.4.5;2.7.11.22;2.7.11.23;4.2.1.24;5.4.2.2;3.4.-.-;1.11.2.-;2.4.1.25;3.2.1.33;2.7.1.-;3.5.4.6;2.3.2.26", "go_molecular_function": "GO:0004340 glucokinase activity;GO:0008865 fructokinase activity;GO:0019158 mannokinase activity;GO:0005524 ATP binding;GO:0005536 D-glucose binding", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005829 cytosol", "go_biological_process": "GO:0001678 intracellular glucose homeostasis;GO:0061621 canonical glycolysis", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q9NFT7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9NGC3-1", "uniprot_id": "CEG1A_DROME", "mass": 108044.0, "length": 995, "protein_name": "Centaurin-gamma-1A", "gene_name": "CenG1A", "organism": "Fruit fly", "refseq_name": "centaurin gamma 1A, isoform A", "refseq_ac": "NP_523562", "gene_names_uniprotkb": "CenG1A; CG31811", "gene_names_refseq": "AGAP; BG:DS08220.1; CG16866; CG16867; CG31811; CG7982; CenG1A; CenG1a; Dmel\\CG31811; cenG1A; cenG1a; cenG; ceng1A", "protein_names_uniprotkb": "Centaurin-gamma-1A", "protein_names_refseq": "CG31811-PA; CenG1A-PA; centaurin gamma 1A, isoform A; centaurin gamma 1A; centaurin gamma-1A", "tax_id": 7227, "disease": "oral squamous cell carcinoma (Disease Ontology:DOID:0050866); syndromic intellectual disability (Disease Ontology:DOID:0050888); autism spectrum disorder (Disease Ontology:DOID:0060041); prostate cancer (Disease Ontology:DOID:10283); cerebral palsy (Disease Ontology:DOID:1969)", "pathway": " (dme:Dmel_CG31811)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "10471707;10731132;12537569;12537572", "class_list": "", "function": "GTPase-activating protein for the ADP ribosylation factor family., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "B7FNK5;I0C0M3;Q6IDF7;Q86P12;Q8MR30;Q95SF3;Q9NKE5;Q9VJV4;Q9VJV5;Q9VJV7", "ec_number_list": "", "go_molecular_function": "GO:0003924 GTPase activity;GO:0005096 GTPase activator activity;GO:0005525 GTP binding;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "GO:0072375 medium-term memory", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q9NGC3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9NHA8-1", "uniprot_id": "BGBP3_DROME", "mass": 55211.0, "length": 490, "protein_name": "Gram-negative bacteria-binding protein 3", "gene_name": "GNBP3", "organism": "Fruit fly", "refseq_name": "Gram-negative bacteria binding protein 3", "refseq_ac": "NP_523986", "gene_names_uniprotkb": "GNBP3; CG5008", "gene_names_refseq": "CG5008; DGNBP-3; Dmel\\CG5008; GNBP-3; GNBP3; GNBP; Gnbp3; Hades; gnbp3", "protein_names_uniprotkb": "Gram-negative bacteria-binding protein 3", "protein_names_refseq": "CG5008-PA; GNBP-3; GNBP3-PA; Gram-negative bacteria binding protein 3; Gram-negative binding protein 3", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG5008)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "10731132;10827089;12537572;17103056", "class_list": "", "function": "Involved in the recognition of invading microorganisms. Binds specifically to beta-1,3-glucan and activates the phenoloxidase cascade (By similarity)., [UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "A0ZX55;A0ZX56;A0ZX59;A0ZX64;Q9VSR4", "ec_number_list": "", "go_molecular_function": "GO:0001530 lipopolysaccharide binding;GO:0001872 (1->3)-beta-D-glucan binding;GO:0038187 pattern recognition receptor activity;GO:0001874 (1->3)-beta-D-glucan immune receptor activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0005615 extracellular space;GO:0009986 cell surface", "go_biological_process": "GO:0002221 pattern recognition receptor signaling pathway;GO:0019732 antifungal humoral response;GO:0005975 carbohydrate metabolic process;GO:0002758 innate immune response-activating signaling pathway;GO:0045088 regulation of innate immune response", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q9NHA8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9NHE5-2", "uniprot_id": "CAPS_DROME", "mass": 172589.0, "length": 1534, "protein_name": "Calcium-dependent secretion activator", "gene_name": "Cadps", "organism": "Fruit fly", "refseq_name": "Calcium-dependent secretion activator, isoform F", "refseq_ac": "NP_001027029", "gene_names_uniprotkb": "Cadps; CG33653; Caps", "gene_names_refseq": "BcDNA:GH07283; CAPS; CG17881; CG18026; CG33653; CG40477; Cadps; Caps; Dmel\\CG33653; SDCAP; caps; cap; dCAPS; dcaps; l(4)102Fb", "protein_names_uniprotkb": "Calcium-dependent secretion activator; Calcium-activated protein for secretion", "protein_names_refseq": "CG33653-PF; Cadps-PF; Calcium-activated protein for secretion; Calcium-dependent secretion activator, isoform F; calcium activated protein for secretion", "tax_id": 7227, "disease": "autism spectrum disorder (Disease Ontology:DOID:0060041)", "pathway": " (dme:Dmel_CG33653)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "10731132;10731138;11516399;12537569;12537572;33925313;40245499", "class_list": "", "function": "Calcium-binding protein involved in exocytosis of vesicles filled with neurotransmitters and neuropeptides. May specifically mediate the Ca(2+)-dependent exocytosis of large dense-core vesicles (DCVs) and other dense-core vesicles. However, it probably also participates in small clear synaptic vesicles (SVs) exocytosis and it is unclear whether its function is related to Ca(2+) triggering., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "H9XVQ4;H9XVQ5;Q4AB01;Q5LJP1;Q8IM88;Q8IM89;Q8MT21;Q9Y135", "ec_number_list": "", "go_molecular_function": "GO:0005509 calcium ion binding;GO:0008289 lipid binding", "go_cellular_component": "GO:0045202 synapse;GO:0030659 cytoplasmic vesicle membrane;GO:0008021 synaptic vesicle", "go_biological_process": "GO:0015031 protein transport;GO:0035249 synaptic transmission, glutamatergic;GO:0016192 vesicle-mediated transport;GO:0007269 neurotransmitter secretion;GO:0006887 exocytosis", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "Q9NHE5-2", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9NIP6-1", "uniprot_id": "CP2B_DROME", "mass": 16507.0, "length": 151, "protein_name": "Cardio acceleratory peptide 2b", "gene_name": "Capa", "organism": "Fruit fly", "refseq_name": "capability", "refseq_ac": "NP_524552", "gene_names_uniprotkb": "Capa; CG15520; MT-CAP2b", "gene_names_refseq": "CAP-2b; CAP2B-1; CAP2B-2; CAP2B-3; CAP2B/pyrokinin; CAP2b-1; CAP2b-2; CAP2b-3; CAP2b; CAPA-PK; CAPA-PVK-1; CAPA-PVK-2; CAPA-PVK/PK; CAPA; CAP[[2b]]; CAP; CG15520; CPPB; Cap-1; Cap-2b; Cap-2; Cap-3; Capa-1; Capa-2; Capa-PK; Capa; Dmel\\CG15520; Drm-CAP-1; Drm-CAP-2; Drm-CAP2b/MT; Drm-MT; Drm-PK-1; Drm-PK; Drm-PVK-1; Drm-PVK-2; Drm-PVK; Drm-capa-1; Drome-capa-1; PVK-2; capa 2; capa-1; capa-2; capa-3; capa; pyrokinin/PBAN-like", "protein_names_uniprotkb": "Cardio acceleratory peptide 2b; CAP2b-1; CAP2b-2; CAP2b-3; Capa-1; Capa-2; Capa-3; Capability protein; Myotropin-CAP2b-like protein; Myotropin; Pyrokinin-1", "protein_names_refseq": "CAP2B-like; CG15520-PA; Capa-PA; Drm-myotropin; TGPSASSGLWFGPRLamide; capability; cardio acceleratory peptide; cardioacceleratory peptide-2b; myotropin-CAP2b-like; periviscerokinin; pyrokinin-1; pyrokinin-like; pyrokinin", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG15520)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "10731132;11179818;11959669;12171930;12177421;12459185;12537569;12537572;16054112", "class_list": "", "function": "CAP-1 and CAP-2, but not CAP-3 are ligands for the Capa receptor (PubMed:12177421, PubMed:12459185). CAP-1 and CAP-2 are probably components of the signal transduction pathway that leads to Malpighian tubule fluid secretion via the second messenger nitric oxide (PubMed:11959669). CAP-3 is a ligand for the PK1-R G protein-coupled receptor (PubMed:16054112)., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9VAE2", "ec_number_list": "", "go_molecular_function": "GO:0005184 neuropeptide hormone activity;GO:0071855 neuropeptide receptor binding;GO:0008613 diuretic hormone activity;GO:0016084 myostimulatory hormone activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0005615 extracellular space", "go_biological_process": "GO:0042045 epithelial fluid transport;GO:0007204 positive regulation of cytosolic calcium ion concentration;GO:0007218 neuropeptide signaling pathway;GO:0006812 monoatomic cation transport;GO:0038060 nitric oxide-cGMP-mediated signaling", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "Q9NIP6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9NJH0-1", "uniprot_id": "EF1G_DROME", "mass": 48968.0, "length": 431, "protein_name": "Elongation factor 1-gamma", "gene_name": "eEF1gamma", "organism": "Fruit fly", "refseq_name": "eukaryotic translation elongation factor 1 gamma, isoform C", "refseq_ac": "NP_001189308", "gene_names_uniprotkb": "eEF1gamma; CG11901; Ef1g", "gene_names_refseq": "CG11901; Dmel\\CG11901; EF1 gamma; EF1gamma; Ef1Bggr; Ef1gamma; Ef1y; eEF1gamma", "protein_names_uniprotkb": "Elongation factor 1-gamma; EF1gamma; eEF-1B gamma", "protein_names_refseq": "CG11901-PC; Ef1gamma; eEF1gamma-PC; eukaryotic translation elongation factor 1 gamma, isoform C", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG11901); (R-DME-156842)", "pathway_count": 2, "publication_count": 7, "publication_id_list": "10731132;12537569;12537572;15952742;19841092;24163433;38264934", "class_list": "", "function": "Microtubule binding protein involved in regulation of microtubule-based transport (PubMed:24163433). Probably plays a role in anchoring the EF-1 complex to other cellular components (By similarity). Probably involved in formation and/or development of mechanosensory organs during metamorphosis (PubMed:38264934). Required for cellular and organismal viability (PubMed:19841092). Not essential for the innate immune response to bacterial infection (PubMed:19841092)., [UniProtKB, UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 1, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A0B4JD11;A4V3K9;Q6NL63;Q8IGT6;Q9NJH1;Q9VAM7", "ec_number_list": "", "go_molecular_function": "GO:0008017 microtubule binding;GO:0003746 translation elongation factor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005856 cytoskeleton;GO:0005853 eukaryotic translation elongation factor 1 complex", "go_biological_process": "GO:0006414 translational elongation;GO:1902513 regulation of organelle transport along microtubule", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "Q9NJH0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9NK54-1", "uniprot_id": "CHIF_DROME", "mass": 189218.0, "length": 1711, "protein_name": "Protein chiffon", "gene_name": "chif", "organism": "Fruit fly", "refseq_name": "chiffon, isoform D", "refseq_ac": "NP_001260499", "gene_names_uniprotkb": "chif; CG5813", "gene_names_refseq": "BG:DS09218.1; BG:DS09218.2; CG5813; CG5817; Chiffon; Chif; DS09218.1; Dbf4; Dmel\\CG5813; chf; chif; fs(2)chiffon", "protein_names_uniprotkb": "Protein chiffon; Chiffon-N", "protein_names_refseq": "CG5813-PD; chif-PD; chiffon, isoform D; chiffon", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG5813); (R-DME-176187); (R-DME-68962)", "pathway_count": 3, "publication_count": 10, "publication_id_list": "10471707;10477296;10731132;12537569;12537572;18327897;25451925;30559249;34908116;35789507", "class_list": "", "function": "A bicistronic gene producing two proteins that are components of different complexes and have separate properties and functions (PubMed:30559249). Full-length protein is proteolytically cleaved, producing a ~50kDa N-terminal product (Chiffon-A) that forms part of the DDK complex; it is unclear if the C-terminal proteolytic product is stable or functional (Probable). Alternative initiation from an internal ribosome entry site produces a C-terminal ~48kDa product (Chiffon-B or Isoform E) that forms part of the CHAT complex (PubMed:30559249). Involved in regulation of gene expression during embryonic development (PubMed:34908116)., [UniProtKB, PubMed, PubMed]; Component of the CHAT histone acetyltransferase complex, which predominantly acetylates histone H3 (PubMed:30559249). As part of the CHAT complex involved in acetylation of histone H3 on 'Lys-10' (H3K9ac), 'Lys-15' (H3K14ac) and 'Lys-19' (H3K18ac), but not 'Lys-25' (H3K24ac) (PubMed:30559249, PubMed:34908116). May also regulate other histone acetyltransferase complexes (PubMed:34908116). Essential for viability (PubMed:30559249). Not required for early stages of embryonic development (PubMed:34908116). May be involved in zygotic genome activation during embryogenesis (PubMed:34908116)., [UniProtKB, PubMed, PubMed]; Regulatory component of the Dbf4-dependent kinase (DDK) complex (PubMed:25451925). Required for the amplification stage, but not the preceding endoreplication stage of DNA replication in egg chamber follicle cells of the ovary (PubMed:25451925). May be involved in initiation of DNA replication; activation of the chorion gene origins (PubMed:10477296). May have a role in eye and thoracic bristle development (PubMed:10477296). Required for female fertility; is not required for oogenesis but is required maternally for early embryo development (PubMed:30559249)., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 5, "predicted_n_glycosites": 0, "predicted_o_glycosites": 5, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 14, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "A0A6H2EHD1;G2J5V4;M9PD16;Q8MRI8;Q95S82;Q9NK53;Q9U9R4;Q9U9R5;Q9VJL0;Q9VJL1", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0030295 protein kinase activator activity;GO:0043539 protein serine/threonine kinase activator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0031431 Dbf4-dependent protein kinase complex;GO:0070775 H3 histone acetyltransferase complex", "go_biological_process": "GO:0006338 chromatin remodeling;GO:0046716 muscle cell cellular homeostasis;GO:0006260 DNA replication;GO:0045740 positive regulation of DNA replication;GO:1901987 regulation of cell cycle phase transition", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "Q9NK54-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9U1H8-1", "uniprot_id": "FACE2_DROME", "mass": 34415.0, "length": 302, "protein_name": "CAAX prenyl protease 2", "gene_name": "Sras", "organism": "Fruit fly", "refseq_name": "severas", "refseq_ac": "NP_524673", "gene_names_uniprotkb": "Sras; CG4852", "gene_names_refseq": "CG4852; Dmel\\CG4852; FAC2_DROME; Sras", "protein_names_uniprotkb": "CAAX prenyl protease 2; 3.4.26.1; FACE-2; Farnesylated proteins-converting enzyme 2; Prenyl protein-specific endoprotease 2; Protein severas", "protein_names_refseq": "CG4852-PA; Sras-PA; prenyl protease type II; severas", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG4852); (R-DME-5689880); (R-DME-9648002)", "pathway_count": 3, "publication_count": 3, "publication_id_list": "10731132;12537569;12537572", "class_list": "", "function": "Protease involved in the processing of a variety of prenylated proteins containing the C-terminal CAAX motif, where C is a cysteine modified with an isoprenoid lipid, A is an aliphatic amino acid and X is any C-terminal amino acid. Proteolytically removes the C-terminal three residues of farnesylated and geranylated proteins, leaving the prenylated cysteine as the new C-terminus. Is able to process K-Ras, N-Ras, H-Ras, RAP1B and G-gamma-1., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q8SZZ3;Q9VRM4", "ec_number_list": "3.6.5.2;3.1.3.48;3.4.26.1;3.4.19.12", "go_molecular_function": "GO:0004222 metalloendopeptidase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0071586 CAAX-box protein processing", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9U1H8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9U405-1", "uniprot_id": "GRAU_DROME", "mass": 65967.0, "length": 570, "protein_name": "Transcription factor grauzone", "gene_name": "grau", "organism": "Fruit fly", "refseq_name": "grauzone", "refseq_ac": "NP_788422", "gene_names_uniprotkb": "grau; CG3282", "gene_names_refseq": "CG3282; CG33133; Dmel\\CG33133; Grau; grau", "protein_names_uniprotkb": "Transcription factor grauzone", "protein_names_refseq": "CG33133-PA; grau-PA; grauzone", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG33133)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "10683177;10731132;10924478;12537569;12537572;14604529", "class_list": "", "function": "Transcription factor essential for the completion of meiosis in oocytes. Grauzone binds to the promoter region of cort via the zf-AD domain and activates cort expression in ovaries., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9W2N7", "ec_number_list": "", "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0008270 zinc ion binding;GO:0000987 cis-regulatory region sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0045143 homologous chromosome segregation;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0007143 female meiotic nuclear division", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q9U405-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9U616-1", "uniprot_id": "GCSH_DROME", "mass": 18002.0, "length": 165, "protein_name": "Glycine cleavage system H protein, mitochondrial", "gene_name": "ppl", "organism": "Fruit fly", "refseq_name": "pumpless", "refseq_ac": "NP_524197", "gene_names_uniprotkb": "ppl; CG7758", "gene_names_refseq": "CG7758; Dmel\\CG7758; l(3)00217; l(3)78Cb; ppl", "protein_names_uniprotkb": "Glycine cleavage system H protein, mitochondrial; Protein pumpless", "protein_names_refseq": "CG7758-PA; ppl-PA; pumpless", "tax_id": 7227, "disease": "multiple mitochondrial dysfunctions syndrome (Disease Ontology:DOID:0070330); amino acid metabolic disorder (Disease Ontology:DOID:9252); glycine encephalopathy (Disease Ontology:DOID:9268)", "pathway": " (dme:Dmel_CG7758); (R-DME-6783984); (R-DME-9857492)", "pathway_count": 3, "publication_count": 4, "publication_id_list": "10556053;10731132;12537569;12537572", "class_list": "", "function": "The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9VP59", "ec_number_list": "", "go_molecular_function": "GO:0140104 molecular carrier activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix;GO:0005960 glycine cleavage complex", "go_biological_process": "GO:0019464 glycine decarboxylation via glycine cleavage system;GO:0006546 glycine catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q9U616-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9U6Y9-1", "uniprot_id": "ANM5_DROME", "mass": 69741.0, "length": 610, "protein_name": "Protein arginine N-methyltransferase 5", "gene_name": "csul", "organism": "Fruit fly", "refseq_name": "capsuleen, isoform A", "refseq_ac": "NP_477184", "gene_names_uniprotkb": "csul; CG3730; DART5", "gene_names_refseq": "ART5; CG3730; Csul; DART5; Dart5; Dmel\\CG3730; JBP1; PRMT5; csul; dPRMT5; dart5; dprmt5", "protein_names_uniprotkb": "Protein arginine N-methyltransferase 5; 2.1.1.-; JBP1 homolog; Protein capsuleen", "protein_names_refseq": "CG3730-PA; capsuleen, isoform A; capsuleenn; csul-PA; drosophila arginine methyltransferase 5", "tax_id": 7227, "disease": "idiopathic scoliosis (Disease Ontology:DOID:0060250); Leydig cell tumor (Disease Ontology:DOID:2696); asthma (Disease Ontology:DOID:2841); seminoma (Disease Ontology:DOID:4440)", "pathway": " (dme:Dmel_CG3730); (R-DME-3214858)", "pathway_count": 2, "publication_count": 10, "publication_id_list": "10531356;10731132;12537569;12537572;14705965;15800004;18369183;19377467;19926723;19959991", "class_list": "", "function": "Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA) (By similarity). Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins SmD1 and SmD3. Required for arginine symmetrical dimethylation of piwi family proteins, piwi, aub and AGO3, during germline development (PubMed:19377467, PubMed:19959991). Required during oogenesis for pole cell formation in the pathway controlled by oskar (osk) and for abdominal segments during early embryogenesis. Involved in nanos (nos) and germ cell mRNAs localization., [UniProtKB, PubMed, PubMed, UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "O46117;Q8MKK9;Q9V7L8", "ec_number_list": "3.6.4.-;2.1.1.-", "go_molecular_function": "GO:0008276 protein methyltransferase activity;GO:0016274 protein-arginine N-methyltransferase activity;GO:0035243 protein-arginine omega-N symmetric methyltransferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol", "go_biological_process": "GO:0030719 P granule organization;GO:0006355 regulation of DNA-templated transcription;GO:0018216 peptidyl-arginine methylation;GO:0008298 intracellular mRNA localization;GO:0007315 pole plasm assembly", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "Q9U6Y9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9U9Q4-1", "uniprot_id": "EIF3H_DROME", "mass": 38408.0, "length": 338, "protein_name": "Eukaryotic translation initiation factor 3 subunit H", "gene_name": "eIF3h", "organism": "Fruit fly", "refseq_name": "eukaryotic translation initiation factor 3 subunit h, isoform A", "refseq_ac": "NP_524834", "gene_names_uniprotkb": "eIF3h; Dmel_CG9124; eIF-3p40; eif3-S3", "gene_names_refseq": "BcDNA:GM14618; CG9124; Dmel\\CG9124; EIF3H; Q9U9Q4; eIF-3p40; eIF-3; eIF3-S3; eIF3h; eIF3p40; eIf3-p44; l(2)k09003", "protein_names_uniprotkb": "Eukaryotic translation initiation factor 3 subunit H; Eukaryotic translation initiation factor 3 subunit 3; eIF3h", "protein_names_refseq": "CG9124-PA; eIF3h-PA; eukaryotic initiation factor 3 p40 subunit; eukaryotic translation initiation factor 3 subunit h, isoform A", "tax_id": 7227, "disease": "prostate cancer (Disease Ontology:DOID:10283); prostate carcinoma (Disease Ontology:DOID:10286); breast cancer (Disease Ontology:DOID:1612)", "pathway": " (dme:Dmel_CG9124); (R-DME-156827); (R-DME-72649); (R-DME-72689); (R-DME-72695); (R-DME-72702)", "pathway_count": 6, "publication_count": 3, "publication_id_list": "10731132;12537572;23716590", "class_list": "", "function": "Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "C0PTU9;Q7KLX2;Q9VMU9", "ec_number_list": "", "go_molecular_function": "GO:0008237 metallopeptidase activity;GO:0003743 translation initiation factor activity;GO:0140492 metal-dependent deubiquitinase activity", "go_cellular_component": "GO:0005829 cytosol;GO:0016282 eukaryotic 43S preinitiation complex;GO:0033290 eukaryotic 48S preinitiation complex;GO:0005852 eukaryotic translation initiation factor 3 complex", "go_biological_process": "GO:0045747 positive regulation of Notch signaling pathway;GO:0006413 translational initiation;GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0001732 formation of cytoplasmic translation initiation complex", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9U9Q4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9UAS6-1", "uniprot_id": "CMTR2_DROME", "mass": 80503.0, "length": 700, "protein_name": "Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2", "gene_name": "cmtr2", "organism": "Fruit fly", "refseq_name": "adrift", "refseq_ac": "NP_477413", "gene_names_uniprotkb": "cmtr2; CG5032; aft", "gene_names_refseq": "CG5032; CMTr2; Dmel\\CG5032; EG:52C10.7; aft", "protein_names_uniprotkb": "Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2; 2.1.1.296; Cap methyltransferase 2 homolog; Cap2 2'O-ribose methyltransferase 2 homolog; FtsJ methyltransferase domain-containing protein 1 homolog; MTr2; Protein Adrift", "protein_names_refseq": "CG5032-PA; adrift; aft-PA", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG5032)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "10068643;10731132;10731137;12537569;12537572", "class_list": "", "function": "Probable S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap2 2'-O-ribose methylation to the 5'-cap structure of mRNAs. May methylate the ribose of the second nucleotide of a m(7)GpppG-capped mRNA (cap0) to produce m(7)GpppRmpNm (cap2) (By similarity). Regulates expression of tracheal genes required for pathfinding on the segmental nerve (PubMed:10068643)., [UniProtKB, PubMed, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A1ZB00;O96839;Q961S3", "ec_number_list": "2.1.1.296", "go_molecular_function": "GO:0004483 methyltransferase cap1 activity;GO:0120550 methyltransferase cap2 activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:1904582 positive regulation of intracellular mRNA localization;GO:0032259 methylation;GO:0006370 7-methylguanosine mRNA capping;GO:0007424 open tracheal system development", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q9UAS6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9V393-1", "uniprot_id": "Q9V393_DROME", "mass": 51237.0, "length": 470, "protein_name": "Kurtz, isoform A; Kurtz, isoform B", "gene_name": "krz", "organism": "Fruit fly", "refseq_name": "kurtz, isoform B", "refseq_ac": "NP_001247400", "gene_names_uniprotkb": "krz; 14; CG1487; Dmel\\CG1487; Dmel_CG1487; Krz; Kurtz; beta-arr2; l(3)S095214", "gene_names_refseq": "0952/14; CG1487; Dmel\\CG1487; Krz; Kurtz; beta-arr2; krz; l(3)S095214", "protein_names_uniprotkb": "Kurtz, isoform A; Kurtz, isoform B", "protein_names_refseq": "CG1487-PB; beta-arrestin-2; beta-arrestin; krz-PB; kurtz, isoform B; kurtz-arrestin; kurtz; kurz", "tax_id": 7227, "disease": "alcohol dependence (Disease Ontology:DOID:0050741); nicotine dependence (Disease Ontology:DOID:0050742); colitis (Disease Ontology:DOID:0060180); retinitis pigmentosa 96 (Disease Ontology:DOID:0061104); metabolic dysfunction and alcohol associated liver disease (Disease Ontology:DOID:0070508); retinitis pigmentosa 47 (Disease Ontology:DOID:0110369); Oguchi disease-1 (Disease Ontology:DOID:0110712); portal hypertension (Disease Ontology:DOID:10762); hypertension (Disease Ontology:DOID:10763); myopia (Disease Ontology:DOID:11830); major depressive disorder (Disease Ontology:DOID:1470); drug psychosis (Disease Ontology:DOID:1742); opiate dependence (Disease Ontology:DOID:2559); glioblastoma (Disease Ontology:DOID:3068); brain infarction (Disease Ontology:DOID:3454); liver cirrhosis (Disease Ontology:DOID:5082); congestive heart failure (Disease Ontology:DOID:6000); hepatocellular carcinoma (Disease Ontology:DOID:684); hereditary night blindness (Disease Ontology:DOID:8498); type 2 diabetes mellitus (Disease Ontology:DOID:9352); heroin dependence (Disease Ontology:DOID:9976)", "pathway": " (dme:Dmel_CG1487); (R-DME-418555); (R-DME-432720); (R-DME-432722); (R-DME-5099900); (R-DME-5674135); (R-DME-5689880); (R-DME-8856825); (R-DME-8856828); (R-DME-9839389)", "pathway_count": 10, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 21, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0001664 G protein-coupled receptor binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0007165 signal transduction;GO:0007600 sensory perception;GO:0002031 G protein-coupled receptor internalization;GO:0048260 positive regulation of receptor-mediated endocytosis;GO:0031648 protein destabilization", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9V393-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9V399-1", "uniprot_id": "CP303_DROME", "mass": 57877.0, "length": 503, "protein_name": "Probable cytochrome P450 303a1", "gene_name": "Cyp303a1", "organism": "Fruit fly", "refseq_name": "cytochrome P450 303a1, isoform B", "refseq_ac": "NP_001285977", "gene_names_uniprotkb": "Cyp303a1; 303a1; BG:DS02740.6; CG4163; CYP303A1-Dm; CYP303A1; Cyp303A1; Dmel\\CG4163; Dmel_CG4163; I(2)35Fb; l(2)35Fb; nompH1; nompH", "gene_names_refseq": "303a1; BG:DS02740.6; CG4163; CYP303A1-Dm; CYP303A1; Cyp303A1; Cyp303a1; Dmel\\CG4163; I(2)35Fb; l(2)35Fb; nompH1; nompH", "protein_names_uniprotkb": "Probable cytochrome P450 303a1; 1.14.-.-; CYPCCCIIIA1", "protein_names_refseq": "CG4163-PB; Cyp303a1-PB; cytochrome P450 303a1, isoform B; lethal(2)35Fb", "tax_id": 7227, "disease": "invasive aspergillosis (Disease Ontology:DOID:0050073); Keshan disease (Disease Ontology:DOID:0050083); alcohol dependence (Disease Ontology:DOID:0050741); nicotine dependence (Disease Ontology:DOID:0050742); renal fibrosis (Disease Ontology:DOID:0050855); oral squamous cell carcinoma (Disease Ontology:DOID:0050866); hepatocellular adenoma (Disease Ontology:DOID:0050868); alcohol-associated liver disease (Disease Ontology:DOID:0070658); metabolic dysfunction-associated steatotic liver disease (Disease Ontology:DOID:0080208); warfarin resistance (Disease Ontology:DOID:0080665); asbestosis (Disease Ontology:DOID:10320); stomach cancer (Disease Ontology:DOID:10534); pre-eclampsia (Disease Ontology:DOID:10591); renal hypertension (Disease Ontology:DOID:1073); hypertension (Disease Ontology:DOID:10763); sickle cell anemia (Disease Ontology:DOID:10923); urinary bladder cancer (Disease Ontology:DOID:11054); familial hyperlipidemia (Disease Ontology:DOID:1168); morbid obesity (Disease Ontology:DOID:11981); hypertrophic cardiomyopathy (Disease Ontology:DOID:11984); acoustic neuroma (Disease Ontology:DOID:12689); dilated cardiomyopathy (Disease Ontology:DOID:12930); lung cancer (Disease Ontology:DOID:1324); eosinophilic esophagitis (Disease Ontology:DOID:13922); alcoholic liver cirrhosis (Disease Ontology:DOID:14018); Plasmodium falciparum malaria (Disease Ontology:DOID:14067); alcohol use disorder (Disease Ontology:DOID:1574); depressive disorder (Disease Ontology:DOID:1596); breast cancer (Disease Ontology:DOID:1612); drug-induced hepatitis (Disease Ontology:DOID:2044); colon cancer (Disease Ontology:DOID:219); asthma (Disease Ontology:DOID:2841); acute kidney failure (Disease Ontology:DOID:3021); high grade glioma (Disease Ontology:DOID:3070); chronic obstructive pulmonary disease (Disease Ontology:DOID:3083); middle cerebral artery infarction (Disease Ontology:DOID:3525); tuberculosis (Disease Ontology:DOID:399); liver disease (Disease Ontology:DOID:409); hyperglycemia (Disease Ontology:DOID:4195); multiple chemical sensitivity (Disease Ontology:DOID:4661); human immunodeficiency virus infectious disease (Disease Ontology:DOID:526); pneumonia (Disease Ontology:DOID:552); head and neck squamous cell carcinoma (Disease Ontology:DOID:5520); myocardial infarction (Disease Ontology:DOID:5844); pulmonary hypertension (Disease Ontology:DOID:6432); hepatocellular carcinoma (Disease Ontology:DOID:684); peptic ulcer disease (Disease Ontology:DOID:750); end stage renal disease (Disease Ontology:DOID:783); extrinsic allergic alveolitis (Disease Ontology:DOID:841); oral cavity cancer (Disease Ontology:DOID:8618); acute myeloid leukemia (Disease Ontology:DOID:9119); colorectal cancer (Disease Ontology:DOID:9256); nasopharynx carcinoma (Disease Ontology:DOID:9261); diabetes mellitus (Disease Ontology:DOID:9351); type 2 diabetes mellitus (Disease Ontology:DOID:9352); steatotic liver disease (Disease Ontology:DOID:9452); multiple myeloma (Disease Ontology:DOID:9538); type 1 diabetes mellitus (Disease Ontology:DOID:9744); neonatal abstinence syndrome (Disease Ontology:DOID:9828); obesity (Disease Ontology:DOID:9970); drug dependence (Disease Ontology:DOID:9974); heroin dependence (Disease Ontology:DOID:9976); hypoglycemia (Disease Ontology:DOID:9993)", "pathway": " (dme:Dmel_CG4163)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "10471707;10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 63, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0004497 monooxygenase activity;GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane;GO:0016020 membrane", "go_biological_process": "GO:0007423 sensory organ development", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "Q9V399-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9V3A4-1", "uniprot_id": "CSUP_DROME", "mass": 48658.0, "length": 449, "protein_name": "Protein catecholamines up", "gene_name": "Catsup", "organism": "Fruit fly", "refseq_name": "catecholamines up", "refseq_ac": "NP_524931", "gene_names_uniprotkb": "Catsup; CG10449", "gene_names_refseq": "Bc; CATSUP; CG10449; Catsup; Dmel\\CG10449; ZipCatsup; catsup; cg10449; dCATSUP; dZIP7; dZipCATSUP; dZipCatsup; fs(2)ltoQT50; l(2)37Bc; l(2)E13; l(2)k05402; l(2)k05424", "protein_names_uniprotkb": "Protein catecholamines up", "protein_names_refseq": "CG10449-PA; Catsup-PA; catecholamines up; catsup", "tax_id": 7227, "disease": "agammaglobulinemia 9 (Disease Ontology:DOID:0081141)", "pathway": " (dme:Dmel_CG10449); (R-DME-442380)", "pathway_count": 2, "publication_count": 4, "publication_id_list": "10471719;10731132;12537569;12537572", "class_list": "", "function": "Negatively regulates tyrosine hydroxylase activity., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005385 zinc ion transmembrane transporter activity;GO:0030234 enzyme regulator activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0030424 axon;GO:0043025 neuronal cell body;GO:0045202 synapse;GO:0097038 perinuclear endoplasmic reticulum", "go_biological_process": "GO:0042069 regulation of catecholamine metabolic process;GO:0010312 detoxification of zinc ion;GO:0071577 zinc ion transmembrane transport;GO:0006882 intracellular zinc ion homeostasis;GO:0007300 ovarian nurse cell to oocyte transport", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q9V3A4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9V3A6-1", "uniprot_id": "ERO1L_DROME", "mass": 55660.0, "length": 483, "protein_name": "Ero1-like protein", "gene_name": "Ero1L", "organism": "Fruit fly", "refseq_name": "endoplasmic reticulum oxidoreductin-1-like", "refseq_ac": "NP_647865", "gene_names_uniprotkb": "Ero1L; CG1333", "gene_names_refseq": "CG1333; Dmel\\CG1333; ERO1-L; Ero1L; Ero1l; Ero1; ero1L; kiga; l(3)64Ag; l(3)SH22", "protein_names_uniprotkb": "Ero1-like protein; 1.8.3.2; Endoplasmic reticulum oxidoreductin-1-like protein", "protein_names_refseq": "CG1333-PB; Ero1-like; Ero1L-PB; endoplasmic reticulum oxidoreductin-1-like; endoplasmic reticulum oxidoreductin-1L; lethal (3) 64Ag", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG1333); (R-DME-264876)", "pathway_count": 2, "publication_count": 4, "publication_id_list": "10671517;10731132;12537572;33925313", "class_list": "", "function": "Oxidoreductase involved in disulfide bond formation in the endoplasmic reticulum. Efficiently reoxidizes pdi-1, the enzyme catalyzing protein disulfide formation, in order to allow pdi-1 to sustain additional rounds of disulfide formation. Following pdi reoxidation, passes its electrons to molecular oxygen via FAD, leading to the production of reactive oxygen species (ROS) in the cell (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "E2QCT2;Q5BI02;Q7KNC7", "ec_number_list": "5.3.4.1;1.8.3.2", "go_molecular_function": "GO:0071949 FAD binding;GO:0015035 protein-disulfide reductase activity;GO:0016971 flavin-dependent sulfhydryl oxidase activity;GO:0016972 thiol oxidase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006457 protein folding;GO:0034975 protein folding in endoplasmic reticulum", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q9V3A6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9V3B4-1", "uniprot_id": "FADD_DROME", "mass": 27421.0, "length": 239, "protein_name": "Fas-associated death domain protein", "gene_name": "Fadd", "organism": "Fruit fly", "refseq_name": "Fas-associated death domain", "refseq_ac": "NP_651006", "gene_names_uniprotkb": "Fadd; BG4; CG12297", "gene_names_refseq": "BG4_DROME; BG4; CG12297; Dmel\\CG12297; FADD; FAD; Fadd; dFADD; dFadd; dfadd; fadd", "protein_names_uniprotkb": "Fas-associated death domain protein; Death domain-containing adapter protein BG4; FAS-associating death domain-containing protein; dFADD", "protein_names_refseq": "BG4; CG12297-PA; Fadd-PA; Fas-associated death domain ortholog; Fas-associated death domain", "tax_id": 7227, "disease": "brain glioma (Disease Ontology:DOID:0060108); immunodeficiency 90 (Disease Ontology:DOID:0061060); Alzheimer's disease (Disease Ontology:DOID:10652); hypertension (Disease Ontology:DOID:10763); prostatic hypertrophy (Disease Ontology:DOID:11132); leukemia (Disease Ontology:DOID:1240); abdominal obesity-metabolic syndrome 1 (Disease Ontology:DOID:14221); depressive disorder (Disease Ontology:DOID:1596); transient cerebral ischemia (Disease Ontology:DOID:224); morphine dependence (Disease Ontology:DOID:2560); middle cerebral artery infarction (Disease Ontology:DOID:3525); acute myeloid leukemia (Disease Ontology:DOID:9119); obesity (Disease Ontology:DOID:9970)", "pathway": " (dme:Dmel_CG12297); (R-DME-214397); (R-DME-214399); (R-DME-214411); (R-DME-214416); (R-DME-3371378); (R-DME-5218900); (R-DME-5357905); (R-DME-5675482); (R-DME-69416)", "pathway_count": 10, "publication_count": 11, "publication_id_list": "10731132;10934188;11018014;12433364;12537572;12732719;15657141;16428381;16767093;17465907;22549468", "class_list": "", "function": "Component of the IMD signaling pathway and is required for the host defense against Gram-negative bacteria. Interacts with Dredd, promotes cleavage of Dredd and is necessary and sufficient for enhancing Dredd-induced apoptosis., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 13, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A4V9R5;A4V9R6;A4V9R7", "ec_number_list": "", "go_molecular_function": "GO:0050700 CARD domain binding;GO:0089720 caspase binding;GO:0005123 death receptor binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0031265 CD95 death-inducing signaling complex", "go_biological_process": "GO:0006955 immune response;GO:0050829 defense response to Gram-negative bacterium;GO:0006915 apoptotic process;GO:0002230 positive regulation of defense response to virus by host;GO:0097191 extrinsic apoptotic signaling pathway", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9V3B4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9V3B6-1", "uniprot_id": "CWC15_DROME", "mass": 28411.0, "length": 259, "protein_name": "Protein CWC15 homolog", "gene_name": "c12.1", "organism": "Fruit fly", "refseq_name": "c12.1", "refseq_ac": "NP_652605", "gene_names_uniprotkb": "c12.1; CG12135", "gene_names_refseq": "C12.1; CG12135; CWC15; Dmel\\CG12135; c12.1; cwc15", "protein_names_uniprotkb": "Protein CWC15 homolog", "protein_names_refseq": "CG12135-PA; c12.1-PA; c12.1", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG12135); (R-DME-72163)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "10731132;12111211;12537572", "class_list": "", "function": "Involved in pre-mRNA splicing., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0071013 catalytic step 2 spliceosome;GO:0071011 precatalytic spliceosome", "go_biological_process": "GO:0000398 mRNA splicing, via spliceosome;GO:0045292 mRNA cis splicing, via spliceosome", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9V3B6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9V3C0-1", "uniprot_id": "DDX41_DROME", "mass": 69488.0, "length": 619, "protein_name": "ATP-dependent RNA helicase abstrakt", "gene_name": "abs", "organism": "Fruit fly", "refseq_name": "abstrakt", "refseq_ac": "NP_524220", "gene_names_uniprotkb": "abs; CG14637", "gene_names_refseq": "ABS; CG14637; DDX41; DmRH23; Dmel\\CG14637; abs; anon-WO0118547.315; l(3)00620; l(3)04505; l(3)06862; l(3)06863", "protein_names_uniprotkb": "ATP-dependent RNA helicase abstrakt; 3.6.4.13; DEAD box protein abstrakt", "protein_names_refseq": "CG14637-PA; abs-PA; abstract; abstrakt", "tax_id": 7227, "disease": "myeloproliferative neoplasm (Disease Ontology:DOID:2226)", "pathway": " (dme:Dmel_CG14637); (R-DME-1834941); (R-DME-72163)", "pathway_count": 3, "publication_count": 6, "publication_id_list": "10607561;10704843;10731132;12537569;12537572;18327897", "class_list": "", "function": "ATP-dependent RNA helicase. Is essential for the directed and fasciculated early outgrowth of the bolwig nerves, as well as for its navigation at later stages. Is required during post-transcriptional gene expression. Plays a role during morphogenetic process, apoptosis and the establishment of cell polarity., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 7, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9U6D0", "ec_number_list": "3.6.4.13;7.2.2.-;3.6.4.-;2.7.7.6;3.6.4.10;3.6.4.6;3.6.4.12;5.6.2.4;5.6.2.5;2.7.4.3;5.6.2.3;3.1.-.-;3.6.1.15;5.2.1.8;3.-.-.-;5.6.1.1;2.7.11.1;3.6.-.-;5.6.2.-", "go_molecular_function": "GO:0003729 mRNA binding;GO:0005524 ATP binding;GO:0008270 zinc ion binding;GO:0016887 ATP hydrolysis activity;GO:0004386 helicase activity", "go_cellular_component": "GO:0005681 spliceosomal complex;GO:0071013 catalytic step 2 spliceosome;GO:0071011 precatalytic spliceosome;GO:0043186 P granule", "go_biological_process": "GO:0010468 regulation of gene expression;GO:0000398 mRNA splicing, via spliceosome", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q9V3C0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9V3D6-1", "uniprot_id": "CPSF2_DROME", "mass": 85418.0, "length": 756, "protein_name": "Probable cleavage and polyadenylation specificity factor subunit 2", "gene_name": "Cpsf100", "organism": "Fruit fly", "refseq_name": "cleavage and polyadenylation specificity factor 100", "refseq_ac": "NP_651658", "gene_names_uniprotkb": "Cpsf100; CG1957", "gene_names_refseq": "BcDNA:LD14168; CG1957; CPSF-100; CPSF100; Cpsf100; Dmel\\CG1957", "protein_names_uniprotkb": "Probable cleavage and polyadenylation specificity factor subunit 2; CPSF 100 kDa subunit; Cleavage and polyadenylation specificity factor 100 kDa subunit", "protein_names_refseq": "CG1957-PA; Cpsf100-PA; cleavage and polyadenylation specificity factor 100", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG1957); (R-DME-159231); (R-DME-73856); (R-DME-77595); (R-DME-9770562)", "pathway_count": 5, "publication_count": 5, "publication_id_list": "10731132;10731138;12537572;18327897;19450530", "class_list": "", "function": "Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. Required for the cotranscriptional processing of 3'-ends of polyadenylated and histone pre-mRNA., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q8IML7", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding", "go_cellular_component": "GO:0005847 mRNA cleavage and polyadenylation specificity factor complex", "go_biological_process": "GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage;GO:0071045 nuclear histone mRNA catabolic process;GO:0180010 co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q9V3D6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9V3R1-1", "uniprot_id": "A36DE_DROME", "mass": 101921.0, "length": 912, "protein_name": "Accessory gland protein Acp36DE", "gene_name": "Acp36DE", "organism": "Fruit fly", "refseq_name": "accessory gland protein 36DE, isoform B", "refseq_ac": "NP_001286040", "gene_names_uniprotkb": "Acp36DE; A36DE; Acp36De; Acp36D; AcpDE36; Acp; CG7157; CT22109; Dmel\\CG7157; Dmel_CG7157; anon-WO0140519.55", "gene_names_refseq": "A36DE; Acp36DE; Acp36De; Acp36D; AcpDE36; Acp; CG7157; CT22109; Dmel\\CG7157; anon-WO0140519.55", "protein_names_uniprotkb": "Accessory gland protein Acp36DE", "protein_names_refseq": "36DE accessory gland protein; Acp36DE-PB; CG7157-PB; accessory gland peptide 36DE; accessory gland protein 36DE, isoform B", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG7157)", "pathway_count": 1, "publication_count": 17, "publication_id_list": "10731132;10731138;11102381;12537568;12537569;12537572;12537573;12537574;12939382;16110336;17569856;17569867;24514904;25589440;26109356;26109357;9474779", "class_list": "", "function": "Responsible for physiological and behavioral changes in mated female flies. Associates with sperm and localizes to specific regions of the female reproductive tract, including the sperm storage organs. It accelerates sperm accumulation into storage but does not mediate the entry of the first sperm into storage. Once sperm storage has initiated it seems to act as a guidance factor helping subsequent sperm move into storage, a corral concentrating sperm around the SSO entrances and/or a trigger for responses within the female that accelerate storage of sperm., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "O46198;Q9U9Y5", "ec_number_list": "", "go_molecular_function": "GO:0005179 hormone activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0005615 extracellular space", "go_biological_process": "GO:0007320 insemination;GO:0042628 mating plug formation;GO:0007618 mating;GO:0046692 sperm competition;GO:0045434 negative regulation of female receptivity, post-mating", "synthesized_glycan_count": 0, "hit_score": 1.8, "record_id": "Q9V3R1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0B4JDC9-1", "uniprot_id": "A0A0B4JDC9_DROME", "mass": 194037.0, "length": 1844, "protein_name": "RIM-binding protein, isoform F", "gene_name": "Rbp", "organism": "Fruit fly", "refseq_name": "RIM-binding protein, isoform F", "refseq_ac": "NP_001189227", "gene_names_uniprotkb": "Rbp; CG14867; CG31302; CG43073; CG5143; CG5152; DRBP; Dmel\\CG43073; Dmel_CG43073; RBP; RIM-BP; RimBP; dRIM-BP; drbp; rbp; rim-bp", "gene_names_refseq": "CG14867; CG31302; CG43073; CG5143; CG5152; DRBP; Dmel\\CG43073; RBP; RIM-BP; Rbp; RimBP; dRIM-BP; drbp; rbp; rim-bp", "protein_names_uniprotkb": "RIM-binding protein, isoform F", "protein_names_refseq": "CG43073-PF; RIM-binding protein, isoform F; Rab3-interacting molecule (RIM)-binding protein; Rbp-PF", "tax_id": 7227, "disease": "dystonia 22, juvenile-onset (Disease Ontology:DOID:0060966); dystonia 22, adult-onset (Disease Ontology:DOID:0060967)", "pathway": " (dme:Dmel_CG43073); (R-DME-181429); (R-DME-181430); (R-DME-196108); (R-DME-210500); (R-DME-212676); (R-DME-264642)", "pathway_count": 7, "publication_count": 12, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357;32369542", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0046872 metal ion binding", "go_cellular_component": "GO:0098831 presynaptic active zone cytoplasmic component;GO:0031594 neuromuscular junction;GO:0048788 cytoskeleton of presynaptic active zone", "go_biological_process": "GO:0048789 cytoskeletal matrix organization at active zone;GO:0007274 neuromuscular synaptic transmission;GO:1990709 presynaptic active zone organization", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "A0A0B4JDC9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0B4K6Y7-1", "uniprot_id": "A0A0B4K6Y7_DROME", "mass": 263845.0, "length": 2395, "protein_name": "Polychaetoid, isoform O", "gene_name": "pyd", "organism": "Fruit fly", "refseq_name": "polychaetoid, isoform O", "refseq_ac": "NP_001246998", "gene_names_uniprotkb": "pyd; CG11782; CG11962; CG12409; CG31349; CG43140; CG9729; CG9731; CG9763; CT36877; DZO-1; Dmel\\CG43140; Dmel_CG43140; Pch; Pyd; Tamou; ZO-1; ZO1; dzo-1; pyd(Z01); tam; xvt", "gene_names_refseq": "CG11782; CG11962; CG12409; CG31349; CG43140; CG9729; CG9731; CG9763; CT36877; DZO-1; Dmel\\CG43140; Pch; Pyd/ZO-1; Pyd; Tamou; ZO-1; ZO1; dzo-1; pyd(Z01); pyd; tam; xvt", "protein_names_uniprotkb": "Polychaetoid, isoform O", "protein_names_refseq": "CG43140-PO; extra verticals; failed fusions; polychaetoid, isoform O; polychaetoid; pyd-PO; tamou", "tax_id": 7227, "disease": "disease of metabolism (Disease Ontology:DOID:0014667); familial hypercholanemia 1 (Disease Ontology:DOID:0061181); progressive familial intrahepatic cholestasis 4 (Disease Ontology:DOID:0070224); metabolic dysfunction and alcohol associated liver disease (Disease Ontology:DOID:0070508); hypertension (Disease Ontology:DOID:10763); uveitis (Disease Ontology:DOID:13141); cholestasis (Disease Ontology:DOID:13580); peptic esophagitis (Disease Ontology:DOID:13976); brain ischemia (Disease Ontology:DOID:2316); bile duct cancer (Disease Ontology:DOID:4606); gallbladder carcinoma (Disease Ontology:DOID:4948); perinatal necrotizing enterocolitis (Disease Ontology:DOID:8677); brain disease (Disease Ontology:DOID:936)", "pathway": " (dme:Dmel_CG43140); (R-DME-2028269); (R-DME-351906); (R-DME-8980692)", "pathway_count": 4, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 13, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0050839 cell adhesion molecule binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005912 adherens junction;GO:0016323 basolateral plasma membrane;GO:0030424 axon;GO:0045177 apical part of cell", "go_biological_process": "GO:0030155 regulation of cell adhesion;GO:0098609 cell-cell adhesion;GO:0016476 regulation of embryonic cell shape;GO:0001745 compound eye morphogenesis;GO:0007391 dorsal closure", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0B4K6Y7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0B4K6L3-1", "uniprot_id": "A0A0B4K6L3_DROME", "mass": 277056.0, "length": 2519, "protein_name": "DH domain-containing protein", "gene_name": "CG14318; CG7397", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform C", "refseq_ac": "NP_001247156", "gene_names_uniprotkb": "CG14318; CG7397; ARHGEF17; CG14318; CG43102; CG7397; Dmel\\CG43102; Dmel_CG43102", "gene_names_refseq": "ARHGEF17; CG14318; CG43102; CG7397; Dmel\\CG43102", "protein_names_uniprotkb": "DH domain-containing protein", "protein_names_refseq": "CG43102-PC; uncharacterized protein, isoform C", "tax_id": 7227, "disease": "intracranial aneurysm (Disease Ontology:DOID:10941)", "pathway": " (dme:Dmel_CG43102); (R-DME-193648); (R-DME-416482); (R-DME-8980692)", "pathway_count": 4, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 5, "predicted_n_glycosites": 0, "predicted_o_glycosites": 5, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005085 guanyl-nucleotide exchange factor activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0035025 positive regulation of Rho protein signal transduction;GO:0030036 actin cytoskeleton organization", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0B4K6L3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0B4KEG0-1", "uniprot_id": "A0A0B4KEG0_DROME", "mass": 46723.0, "length": 413, "protein_name": "NAD kinase 2, mitochondrial", "gene_name": "Nadk2", "organism": "Fruit fly", "refseq_name": "NAD kinase 2, mitochondrial, isoform E", "refseq_ac": "NP_001260818", "gene_names_uniprotkb": "Nadk2; CG30346; CG8080; Dmel\\CG8080; Dmel_CG8080; NADK2", "gene_names_refseq": "CG30346; CG8080; Dmel\\CG8080; NADK2; Nadk2", "protein_names_uniprotkb": "NAD kinase 2, mitochondrial; 2.7.1.23; NAD kinase domain-containing protein 1, mitochondrial", "protein_names_refseq": "CG8080-PE; NAD kinase 2, mitochondrial, isoform E; Nadk2-PE", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG8080); (R-DME-196807); (R-DME-9837999)", "pathway_count": 3, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "Mitochondrial NAD(+) kinase that phosphorylates NAD(+) to yield NADP(+). Can use both ATP or inorganic polyphosphate as the phosphoryl donor., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.1.23;1.1.1.40;1.1.1.38;1.1.1.39;1.2.4.2;1.1.1.35;1.1.1.-;1.1.1.62;1.1.1.51;1.1.1.53;3.5.3.1;1.4.1.3;2.7.11.2;2.7.11.-;7.1.2.2;1.2.4.1;3.4.21.53;7.1.1.2;4.98.1.1;1.1.1.37;4.2.1.3;5.6.2.3;1.2.1.3;6.1.1.5;1.3.8.1;1.3.8.5;2.3.1.-;2.8.3.5;2.3.-.-;2.3.1.9;4.2.1.2;2.3.3.16;5.3.3.21", "go_molecular_function": "GO:0003951 NAD+ kinase activity;GO:0005524 ATP binding;GO:0042803 protein homodimerization activity", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0006741 NADP+ biosynthetic process;GO:0019674 NAD+ metabolic process", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0B4KEG0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0B4K6A8-1", "uniprot_id": "A0A0B4K6A8_DROME", "mass": 12674.0, "length": 116, "protein_name": "Seminal fluid protein", "gene_name": "Dmel\\CG43175", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform A", "refseq_ac": "NP_001247154", "gene_names_uniprotkb": "Dmel\\CG43175; CG43175; Dmel_CG43175", "gene_names_refseq": "CG43175; Dmel\\CG43175", "protein_names_uniprotkb": "Seminal fluid protein", "protein_names_refseq": "CG43175-PA; uncharacterized protein, isoform A", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG43175)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "GO:0009611 response to wounding", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0B4K6A8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0B4K765-1", "uniprot_id": "A0A0B4K765_DROME", "mass": 221037.0, "length": 2066, "protein_name": "Paired amphipathic helix protein Sin3a", "gene_name": "Sin3A", "organism": "Fruit fly", "refseq_name": "Sin3A, isoform G", "refseq_ac": "NP_001246282", "gene_names_uniprotkb": "Sin3A; 159A11T; 15; 3; CG8815; Dmel\\CG8815; Dmel_CG8815; ES2-3; ESTS:159A11T; EY2-9; SIN3A; SIN3; Sin 3A; Sin3a; Sin3; dSin3A; dSin3; l(2)08269; l(2)k02703; l(2)k05415; l(2)k09715; ld; sin3A; sin3a; sin3; sni3", "gene_names_refseq": "159A11T; 27/3; 97/15; CG8815; Dmel\\CG8815; ES2-3; ESTS:159A11T; EY2-9; SIN3A; SIN3; Sin 3A; Sin3A; Sin3a; Sin3; dSin3A; dSin3; l(2)08269; l(2)k02703; l(2)k05415; l(2)k09715; ld; sin3A; sin3a; sin3; sni3", "protein_names_uniprotkb": "Paired amphipathic helix protein Sin3a; Histone deacetylase complex subunit Sin3a; Transcriptional corepressor Sin3a", "protein_names_refseq": "CG8815-PG; Sin3A, isoform G; Sin3A-PG; enhancer of GMR-sina 2-3", "tax_id": 7227, "disease": "developmental disorder of mental health (Disease Ontology:DOID:0060037); chromosome 15q24 deletion syndrome (Disease Ontology:DOID:0060395); Huntington's disease (Disease Ontology:DOID:12858); cancer (Disease Ontology:DOID:162); transient cerebral ischemia (Disease Ontology:DOID:224)", "pathway": " (R-DME-400206); (R-DME-8936459); (R-DME-9707564); (R-DME-9824594); (R-DME-9825892)", "pathway_count": 5, "publication_count": 13, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357;33925313;40245499", "class_list": "", "function": "Acts as a transcriptional repressor. Corepressor for REST. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Also interacts with MXD1-MAX heterodimers to repress transcription by tethering SIN3A to DNA. Acts cooperatively with OGT to repress transcription in parallel with histone deacetylation. Involved in the control of the circadian rhythms. Required for the transcriptional repression of circadian target genes, such as PER1, mediated by the large PER complex through histone deacetylation. Cooperates with FOXK1 to regulate cell cycle progression probably by repressing cell cycle inhibitor genes expression. Required for cortical neuron differentiation and callosal axon elongation., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 4, "predicted_n_glycosites": 0, "predicted_o_glycosites": 4, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 3, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 3, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 3, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 5, "glyco_site_count": 7, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0046982 protein heterodimerization activity;GO:0003714 transcription corepressor activity;GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding;GO:0003682 chromatin binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005730 nucleolus;GO:0017053 transcription repressor complex;GO:0000785 chromatin;GO:0070822 Sin3-type complex", "go_biological_process": "GO:0010633 negative regulation of epithelial cell migration;GO:0010631 epithelial cell migration;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0045892 negative regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 1.8, "record_id": "A0A0B4K765-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0B4KFB3-1", "uniprot_id": "A0A0B4KFB3_DROME", "mass": 37004.0, "length": 331, "protein_name": "NADP-retinol dehydrogenase", "gene_name": "Dmel\\CG30495", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform B", "refseq_ac": "NP_001260785", "gene_names_uniprotkb": "Dmel\\CG30495; CG17986; CG30495; Dmel_CG30495", "gene_names_refseq": "CG17986; CG30495; Dmel\\CG30495", "protein_names_uniprotkb": "NADP-retinol dehydrogenase; 1.1.1.300", "protein_names_refseq": "CG30495-PB; uncharacterized protein, isoform B", "tax_id": 7227, "disease": "Leber congenital amaurosis 13 (Disease Ontology:DOID:0110330); Leber congenital amaurosis (Disease Ontology:DOID:14791); Leber hereditary optic neuropathy (Disease Ontology:DOID:705)", "pathway": " (dme:Dmel_CG30495); (R-DME-2453902)", "pathway_count": 2, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.1.1.300;1.1.1.21;1.1.1.372;1.1.1.54", "go_molecular_function": "GO:0052650 all-trans-retinol dehydrogenase (NADP+) activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0042574 retinal metabolic process", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0B4KFB3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0B4KF15-1", "uniprot_id": "A0A0B4KF15_DROME", "mass": 162601.0, "length": 1472, "protein_name": "Mangetout, isoform G", "gene_name": "mtt", "organism": "Fruit fly", "refseq_name": "mangetout, isoform G", "refseq_ac": "NP_001260806", "gene_names_uniprotkb": "mtt; 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Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004930 G protein-coupled receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane;GO:0030425 dendrite", "go_biological_process": "GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway;GO:0008343 adult feeding behavior;GO:0017085 response to insecticide", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0B4KF15-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0B4KEL4-1", "uniprot_id": "A0A0B4KEL4_DROME", "mass": 98329.0, "length": 875, "protein_name": "FXNA-like protease", "gene_name": "Dmel\\CG13160", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform B", "refseq_ac": "NP_001260918", "gene_names_uniprotkb": "Dmel\\CG13160; 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Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. 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Sulfotransferase 3, isoform C", "gene_name": "St3", "organism": "Fruit fly", "refseq_name": "sulfotransferase 3, isoform C", "refseq_ac": "NP_001261155", "gene_names_uniprotkb": "St3; CG11293; CG44167; CG5431; Dmel\\CG44167; Dmel_CG44167; dmST3; st3", "gene_names_refseq": "CG11293; CG44167; CG5431; Dmel\\CG44167; St3; dmST3; st3", "protein_names_uniprotkb": "2.8.2.-; Sulfotransferase 3, isoform C", "protein_names_refseq": "CG44167-PC; St3-PC; sulfotransferase 3, isoform C", "tax_id": 7227, "disease": "benign neoplasm (Disease Ontology:DOID:0060072); autosomal recessive congenital ichthyosis 14 (Disease Ontology:DOID:0080258); prostate cancer (Disease Ontology:DOID:10283); stomach cancer (Disease Ontology:DOID:10534); urinary bladder cancer (Disease Ontology:DOID:11054); lung cancer (Disease Ontology:DOID:1324); endometrial cancer (Disease Ontology:DOID:1380); breast cancer (Disease Ontology:DOID:1612); esophagus squamous cell carcinoma (Disease Ontology:DOID:3748); lung squamous cell carcinoma (Disease Ontology:DOID:3907); lung adenocarcinoma (Disease Ontology:DOID:3910)", "pathway": " (dme:Dmel_CG44167)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 11, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008146 sulfotransferase activity", "go_cellular_component": "GO:0005829 cytosol;GO:0005737 cytoplasm", "go_biological_process": "GO:0051923 sulfation;GO:0006805 xenobiotic metabolic process;GO:0042742 defense response to bacterium", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0B4KF40-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0B4K7J4-1", "uniprot_id": "A0A0B4K7J4_DROME", "mass": 140435.0, "length": 1279, "protein_name": "Glial cell line-derived neurotrophic family receptor-like, isoform E", "gene_name": "Gfrl", "organism": "Fruit fly", "refseq_name": "glial cell line-derived neurotrophic family receptor-like, isoform E", "refseq_ac": "NP_001247206", "gene_names_uniprotkb": "Gfrl; BcDNA:GH26447; CG17203; CG17204; CG17205; CG17208; CG33518; CG34118; CG34119; CG42401; CG42625; CG42801; CG43224; CG4342; DmGfrl; Dmel\\CG43224; Dmel_CG43224; dGFRLAb; dGFRLA; mun", "gene_names_refseq": "BcDNA:GH26447; CG17203; CG17204; CG17205; CG17208; CG33518; CG34118; CG34119; CG42401; CG42625; CG42801; CG43224; CG4342; DmGfrl; Dmel\\CG43224; Gfrl; dGFRLAb; dGFRLA; mun", "protein_names_uniprotkb": "Glial cell line-derived neurotrophic family receptor-like, isoform E", "protein_names_refseq": "CG43224-PE; GDNF Receptor-like; Gfrl-PE; glial cell line-derived neurotrophic family receptor-like, isoform E; munin", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG43224); (R-DME-8853659)", "pathway_count": 2, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0050839 cell adhesion molecule binding;GO:0038023 signaling receptor activity", "go_cellular_component": "GO:0009897 external side of plasma membrane;GO:0043235 receptor complex", "go_biological_process": "GO:0007169 cell surface receptor protein tyrosine kinase signaling pathway;GO:0007399 nervous system development", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0B4K7J4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VF71-1", "uniprot_id": "CUTC_DROME", "mass": 28916.0, "length": 263, "protein_name": "Copper homeostasis protein cutC homolog", "gene_name": "Dmel\\CG6136", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform B", "refseq_ac": "NP_001189224", "gene_names_uniprotkb": "Dmel\\CG6136; CG6136; Dmel_CG6136; dCutC", "gene_names_refseq": "CG6136; Dmel\\CG6136; dCutC", "protein_names_uniprotkb": "Copper homeostasis protein cutC homolog", "protein_names_refseq": "CG6136-PB; uncharacterized protein, isoform B", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG6136)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "Involved in copper homeostasis., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005507 copper ion binding", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "Q9VF71-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VHS2-1", "uniprot_id": "COX7A_DROME", "mass": 9902.0, "length": 89, "protein_name": "Cytochrome c oxidase subunit 7A, mitochondrial", "gene_name": "COX7A", "organism": "Fruit fly", "refseq_name": "cytochrome c oxidase subunit 7A, isoform A", "refseq_ac": "NP_652184", "gene_names_uniprotkb": "COX7A; CG9603; COX-7A; COX7A1; COX7a; COXJ; COXK; Cox7a; Dmel\\CG9603; Dmel_CG9603; Q9VHS2; VIIa; cox7a", "gene_names_refseq": "CG9603; COX-7A; COX7A1; COX7A; COX7a; COXJ; COXK; Cox7a; Dmel\\CG9603; Q9VHS2; VIIa; cox7a", "protein_names_uniprotkb": "Cytochrome c oxidase subunit 7A, mitochondrial; Cytochrome c oxidase subunit VIIa", "protein_names_refseq": "CG9603-PA; COX7A-PA; cytochrome c oxidase VIIa; cytochrome c oxidase polypeptide VIIa; cytochrome c oxidase subunit 7A, isoform A", "tax_id": 7227, "disease": "dilated cardiomyopathy (Disease Ontology:DOID:12930); epilepsy (Disease Ontology:DOID:1826); cytochrome-c oxidase deficiency disease (Disease Ontology:DOID:3762)", "pathway": " (dme:Dmel_CG9603); (R-DME-5628897); (R-DME-611105); (R-DME-9707564); (R-DME-9864848)", "pathway_count": 5, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "B9EQX3", "ec_number_list": "", "go_molecular_function": "GO:0030674 protein-macromolecule adaptor activity;GO:0016491 oxidoreductase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane;GO:0031966 mitochondrial membrane;GO:0045277 respiratory chain complex IV;GO:0098803 respiratory chain complex", "go_biological_process": "GO:0006123 mitochondrial electron transport, cytochrome c to oxygen;GO:0006119 oxidative phosphorylation;GO:1902600 proton transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VHS2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VE34-1", "uniprot_id": "EPG5_DROME", "mass": 280692.0, "length": 2455, "protein_name": "Ectopic P granules protein 5 homolog", "gene_name": "Epg5", "organism": "Fruit fly", "refseq_name": "ectopic P-granules autophagy protein 5, isoform C", "refseq_ac": "NP_650752", "gene_names_uniprotkb": "Epg5; CG14299; Dmel\\CG14299; Dmel_CG14299; EPG5; epg5", "gene_names_refseq": "CG14299; Dmel\\CG14299; EPG5; Epg5; epg5", "protein_names_uniprotkb": "Ectopic P granules protein 5 homolog", "protein_names_refseq": "CG14299-PC; Epg5-PC; ectopic P-granules autophagy protein 5, isoform C", "tax_id": 7227, "disease": "Vici syndrome (Disease Ontology:DOID:0060356); retinitis pigmentosa (Disease Ontology:DOID:10584); amyotrophic lateral sclerosis (Disease Ontology:DOID:332)", "pathway": " (dme:Dmel_CG14299)", "pathway_count": 1, "publication_count": 14, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;18327897;25589440;26109356;26109357;26917586", "class_list": "", "function": "Involved in autophagy. Plays a role in late steps of autophagy., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q8MT53", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0048471 perinuclear region of cytoplasm;GO:0005764 lysosome", "go_biological_process": "GO:0097352 autophagosome maturation;GO:0006914 autophagy", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "Q9VE34-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VGW1-1", "uniprot_id": "CAD86_DROME", "mass": 220408.0, "length": 1943, "protein_name": "Cadherin-86C", "gene_name": "Cad86C", "organism": "Fruit fly", "refseq_name": "cadherin 86C, isoform D", "refseq_ac": "NP_001247031", "gene_names_uniprotkb": "Cad86C; BcDNA:LP07955; CG31393; CG31425; CG33112; CG42601; CG4509; CG4655; CT14654; CT15041; DCad86C; Dmel\\CG42601; Dmel_CG42601", "gene_names_refseq": "BcDNA:LP07955; CG31393; CG31425; CG33112; CG42601; CG4509; CG4655; CT14654; CT15041; Cad86C; DCad86C; Dmel\\CG42601", "protein_names_uniprotkb": "Cadherin-86C", "protein_names_refseq": "CG42601-PD; Cad86C-PD; cadherin 86C, isoform D; cadherin Cad86C", "tax_id": 7227, "disease": "cone-rod dystrophy 15 (Disease Ontology:DOID:0111021)", "pathway": " (dme:Dmel_CG42601)", "pathway_count": 1, "publication_count": 14, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17113384;17569856;17569867;18539010;25589440;26109356;26109357", "class_list": "", "function": "Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 9, "predicted_n_glycosites": 9, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 9, "binding_glycan_count": 0, "secondary_ac_list": "A0A0B4K655;A0A0B4K6E3;B3GN10;Q8MZ37", "ec_number_list": "", "go_molecular_function": "GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005912 adherens junction;GO:0035003 subapical complex", "go_biological_process": "GO:0007409 axonogenesis;GO:0030855 epithelial cell differentiation;GO:0008360 regulation of cell shape;GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules;GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "Q9VGW1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VCA8-1", "uniprot_id": "ANKHM_DROME", "mass": 423201.0, "length": 4001, "protein_name": "Ankyrin repeat and KH domain-containing protein mask", "gene_name": "mask", "organism": "Fruit fly", "refseq_name": "multiple ankyrin repeats single KH domain, isoform A", "refseq_ac": "NP_788733", "gene_names_uniprotkb": "mask; CG18671; CG31138; CG33106; CG6268; CG6313; Dmel\\CG33106; Dmel_CG33106; EC3-6; MASK; Mask; cg6313", "gene_names_refseq": "CG18671; CG31138; CG33106; CG6268; CG6313; Dmel\\CG33106; EC3-6; MASK; Mask; cg6313; mask", "protein_names_uniprotkb": "Ankyrin repeat and KH domain-containing protein mask; Multiple ankyrin repeat single KH domain-containing protein", "protein_names_refseq": "CG33106-PA; mask-PA; multiple ankyrin repeats single KH domain, isoform A", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG33106)", "pathway_count": 1, "publication_count": 16, "publication_id_list": "10731132;11782402;12537568;12537569;12537572;12537573;12537574;16110336;17372656;17569856;17569867;18327897;25589440;26109356;26109357;26251439", "class_list": "", "function": "Mediator of receptor tyrosine kinase (RTK) signaling, and may act either downstream of MAPK or transduce signaling through a parallel branch of the RTK pathway (PubMed:11782402). Required for the development and organization of indirect flight muscle sarcomeres by regulating the formation of M line and H zone and the correct assembly of thick and thin filaments in the sarcomere (PubMed:26251439)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 11, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "Q6NP19;Q8SX96;Q8T0H2;Q8T8Q4;Q8WRQ7", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding;GO:0019901 protein kinase binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0030018 Z disc;GO:0031430 M band", "go_biological_process": "GO:0045087 innate immune response;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0045747 positive regulation of Notch signaling pathway;GO:0035313 wound healing, spreading of epidermal cells;GO:0048010 vascular endothelial growth factor receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "Q9VCA8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9V5L3-1", "uniprot_id": "C49A1_DROME", "mass": 65902.0, "length": 589, "protein_name": "Probable cytochrome P450 49a1", "gene_name": "Cyp49a1", "organism": "Fruit fly", "refseq_name": "cytochrome P450 49a1, isoform E", "refseq_ac": "NP_001246256", "gene_names_uniprotkb": "Cyp49a1; 49a1; CG12894; CG18377; Cyp49A1; Cyp49a1p; Dmel\\CG18377; Dmel_CG18377", "gene_names_refseq": "49a1; CG12894; CG18377; Cyp49A1; Cyp49a1p; Cyp49a1; Dmel\\CG18377", "protein_names_uniprotkb": "Probable cytochrome P450 49a1; 1.14.-.-; CYPXLIXA1", "protein_names_refseq": "CG18377-PE; Cyp49a1-PE; cytochrome P450 49a1, isoform E; cytochrome P450", "tax_id": 7227, "disease": "colorectal adenoma (Disease Ontology:DOID:0050860); colorectal adenocarcinoma (Disease Ontology:DOID:0050861); oral squamous cell carcinoma (Disease Ontology:DOID:0050866); infantile hypercalcemia 1 (Disease Ontology:DOID:0061136); metabolic dysfunction-associated steatohepatitis (Disease Ontology:DOID:0080547); childhood-onset asthma (Disease Ontology:DOID:0080815); vitamin D-dependent rickets type 1A (Disease Ontology:DOID:0080886); pre-eclampsia (Disease Ontology:DOID:10591); rickets (Disease Ontology:DOID:10609); gestational diabetes (Disease Ontology:DOID:11714); lung cancer (Disease Ontology:DOID:1324); extrahepatic cholestasis (Disease Ontology:DOID:13619); alcohol use disorder (Disease Ontology:DOID:1574); rectum cancer (Disease Ontology:DOID:1993); hepatitis B (Disease Ontology:DOID:2043); colon cancer (Disease Ontology:DOID:219); colon adenocarcinoma (Disease Ontology:DOID:234); nephrosis (Disease Ontology:DOID:2527); asthma (Disease Ontology:DOID:2841); pulmonary tuberculosis (Disease Ontology:DOID:2957); acute kidney failure (Disease Ontology:DOID:3021); chronic obstructive pulmonary disease (Disease Ontology:DOID:3083); breast carcinoma (Disease Ontology:DOID:3459); ovary adenocarcinoma (Disease Ontology:DOID:3713); esophagus squamous cell carcinoma (Disease Ontology:DOID:3748); lung carcinoma (Disease Ontology:DOID:3905); lung non-small cell carcinoma (Disease Ontology:DOID:3908); lung adenocarcinoma (Disease Ontology:DOID:3910); cerebrotendinous xanthomatosis (Disease Ontology:DOID:4810); esophagus adenocarcinoma (Disease Ontology:DOID:4914); esophageal cancer (Disease Ontology:DOID:5041); lung small cell carcinoma (Disease Ontology:DOID:5409); ulcerative colitis (Disease Ontology:DOID:8577); Wilson disease (Disease Ontology:DOID:893); colorectal cancer (Disease Ontology:DOID:9256); type 1 diabetes mellitus (Disease Ontology:DOID:9744); obesity (Disease Ontology:DOID:9970)", "pathway": " (dme:Dmel_CG18377)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 37, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A4UZC2;B8A3V2;Q8MZH1;Q8SY18", "ec_number_list": "", "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0004497 monooxygenase activity;GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane;GO:0016020 membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "Q9V5L3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VAI0-1", "uniprot_id": "GNA1_DROME", "mass": 24492.0, "length": 219, "protein_name": "Probable glucosamine 6-phosphate N-acetyltransferase", "gene_name": "Gnpnat", "organism": "Fruit fly", "refseq_name": "Glucosamine-phosphate N-acetyltransferase, isoform A", "refseq_ac": "NP_651719", "gene_names_uniprotkb": "Gnpnat; CG1969; Dmel\\CG1969; Dmel_CG1969; GNPNAT", "gene_names_refseq": "CG1969; Dmel\\CG1969; GNPNAT; Gnpnat", "protein_names_uniprotkb": "Probable glucosamine 6-phosphate N-acetyltransferase; 2.3.1.4; Phosphoglucosamine acetylase; Phosphoglucosamine transacetylase", "protein_names_refseq": "CG1969-PA; Glucosamine-phosphate N-acetyltransferase, isoform A; Gnpnat-PA; glucosamine-phosphate N-acetyltransferase", "tax_id": 7227, "disease": "keratosis follicularis spinulosa decalvans (Disease Ontology:DOID:0080753); cancer (Disease Ontology:DOID:162)", "pathway": " (dme:Dmel_CG1969); (R-DME-446210)", "pathway_count": 2, "publication_count": 12, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.3.1.4", "go_molecular_function": "GO:0004343 glucosamine 6-phosphate N-acetyltransferase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0006048 UDP-N-acetylglucosamine biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "Q9VAI0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9W2F2-1", "uniprot_id": "DCAF1_DROME", "mass": 172085.0, "length": 1544, "protein_name": "Protein mahjong", "gene_name": "mahj", "organism": "Fruit fly", "refseq_name": "mahjong, isoform B", "refseq_ac": "NP_001246451", "gene_names_uniprotkb": "mahj; BcDNA:SD08722; CG10080; Dmel\\CG10080; Dmel_CG10080; Mahj; VprBP; anon-WO0172774.151", "gene_names_refseq": "BcDNA:SD08722; CG10080; Dmel\\CG10080; Mahj; VprBP; anon-WO0172774.151; mahj", "protein_names_uniprotkb": "Protein mahjong; DDB1- and CUL4-associated factor-like 1; VPRBP-like protein", "protein_names_refseq": "CG10080-PB; mahj-PB; mahjong, isoform B; mahjong", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG10080); (R-DME-983168)", "pathway_count": 2, "publication_count": 13, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;18327897;20644714;25589440;26109356;26109357", "class_list": "", "function": "Probable substrate recognition component of tsome E3 ubiquitin-protein ligase complex (By similarity). Plays a key role in cell competition via its interaction with l(2)gl., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q5U167;Q86PE6;Q8MT13", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0080008 Cul4-RING E3 ubiquitin ligase complex", "go_biological_process": "GO:0016567 protein ubiquitination;GO:0035212 cell competition in a multicellular organism", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "Q9W2F2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VHN3-1", "uniprot_id": "CDPF1_DROME", "mass": 17872.0, "length": 154, "protein_name": "Cysteine-rich DPF motif domain-containing protein 1", "gene_name": "Dmel\\CG11755", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform B", "refseq_ac": "NP_001262381", "gene_names_uniprotkb": "Dmel\\CG11755; CG11755; Dmel_CG11755", "gene_names_refseq": "CG11755; Dmel\\CG11755", "protein_names_uniprotkb": "Cysteine-rich DPF motif domain-containing protein 1", "protein_names_refseq": "CG11755-PB; uncharacterized protein, isoform B", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG11755)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VHN3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VHH9-1", "uniprot_id": "JHD1_DROME", "mass": 146178.0, "length": 1345, "protein_name": "JmjC domain-containing histone demethylation protein 1", "gene_name": "Kdm2", "organism": "Fruit fly", "refseq_name": "lysine demethylase 2, isoform C", "refseq_ac": "NP_001262400", "gene_names_uniprotkb": "Kdm2; CG11033; Dmel\\CG11033; Dmel_CG11033; FBXL19; JHDM1; Jhd1; KDM2; dKDM2; dKdm2; dRAF1; dkdm2; kdm2", "gene_names_refseq": "CG11033; Dmel\\CG11033; FBXL19; JHDM1; KDM2; Kdm2; dKDM2; dKdm2; dRAF1; dkdm2; kdm2", "protein_names_uniprotkb": "JmjC domain-containing histone demethylation protein 1; 1.14.11.27; Lysine (K)-specific demethylase 2; [Histone-H3]-lysine-36 demethylase 1", "protein_names_refseq": "CG11033-PC; JmjC domain-containing histone demethylase 1; Kdm2-PC; dRING-associated factor 1; lysine (K)-specific demethylase 2; lysine demethylase 2, isoform C", "tax_id": 7227, "disease": "T-cell non-Hodgkin lymphoma (Disease Ontology:DOID:0081312); melanoma (Disease Ontology:DOID:1909); pancreatic ductal carcinoma (Disease Ontology:DOID:3587); lung non-small cell carcinoma (Disease Ontology:DOID:3908); acute lymphoblastic leukemia (Disease Ontology:DOID:9952)", "pathway": " (dme:Dmel_CG11033)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;18327897;25589440;26109356;26109357", "class_list": "", "function": "Histone demethylase that specifically demethylates 'Lys-36' of histone H3, thereby playing a central role in histone code., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q7YU79", "ec_number_list": "1.14.11.27;1.14.11.-", "go_molecular_function": "GO:0051864 histone H3K36 demethylase activity;GO:0034647 histone H3K4me/H3K4me2/H3K4me3 demethylase activity;GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0003712 transcription coregulator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0019005 SCF ubiquitin ligase complex;GO:0031519 PcG protein complex", "go_biological_process": "GO:0006338 chromatin remodeling;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0006325 chromatin organization;GO:0007379 segment specification", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "Q9VHH9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9V6L0-1", "uniprot_id": "KDM4B_DROME", "mass": 66437.0, "length": 590, "protein_name": "Probable lysine-specific demethylase 4B", "gene_name": "Kdm4B", "organism": "Fruit fly", "refseq_name": "lysine demethylase 4B, isoform B", "refseq_ac": "NP_001163137", "gene_names_uniprotkb": "Kdm4B; CG33182; CG4037; Dmel\\CG33182; Dmel_CG33182; KDM4B; Kdm4b; dJMJD2(2); dKDM4B; dKdm4B; kdm4b", "gene_names_refseq": "CG33182; CG4037; Dmel\\CG33182; KDM4B; Kdm4B; Kdm4b; dJMJD2(2); dKDM4B; dKdm4B; kdm4b", "protein_names_uniprotkb": "Probable lysine-specific demethylase 4B; 1.14.11.66; Probable JmjC domain-containing histone demethylation protein 3B; Probable [histone H3]-trimethyl-L-lysine(9) demethylase 4B", "protein_names_refseq": "CG33182-PB; Kdm4B-PB; histone demethylase 4B; lysine (K)-specific demethylase 4B; lysine demethylase 4B, isoform B", "tax_id": 7227, "disease": "medulloblastoma (Disease Ontology:DOID:0050902); withdrawal disorder (Disease Ontology:DOID:0060001); autosomal dominant intellectual developmental disorder 65 (Disease Ontology:DOID:0061038); prostate cancer (Disease Ontology:DOID:10283); stomach cancer (Disease Ontology:DOID:10534); urinary bladder cancer (Disease Ontology:DOID:11054); head and neck cancer (Disease Ontology:DOID:11934); autistic disorder (Disease Ontology:DOID:12849); lung cancer (Disease Ontology:DOID:1324); alcohol use disorder (Disease Ontology:DOID:1574); breast cancer (Disease Ontology:DOID:1612); nephroblastoma (Disease Ontology:DOID:2154); esophagus squamous cell carcinoma (Disease Ontology:DOID:3748); renal cell carcinoma (Disease Ontology:DOID:4450); stomach carcinoma (Disease Ontology:DOID:5517); malignant peripheral nerve sheath tumor (Disease Ontology:DOID:5940); colorectal cancer (Disease Ontology:DOID:9256); alopecia areata (Disease Ontology:DOID:986)", "pathway": " (dme:Dmel_CG33182); (R-DME-5625886)", "pathway_count": 2, "publication_count": 13, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357;28604694;40245499", "class_list": "", "function": "Probable histone demethylase that specifically demethylates 'Lys-9' and 'Lys-36' residues of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 6, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 6, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 6, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 18, "glyco_site_count": 6, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.11.1;2.7.11.13;1.14.11.69;1.14.11.66", "go_molecular_function": "GO:0051864 histone H3K36 demethylase activity;GO:0046872 metal ion binding;GO:0032454 histone H3K9 demethylase activity;GO:0140684 histone H3K9me2/H3K9me3 demethylase activity;GO:0140681 histone H3K36me2/H3K36me3 demethylase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0000785 chromatin", "go_biological_process": "GO:0006338 chromatin remodeling;GO:0006351 DNA-templated transcription;GO:0045892 negative regulation of DNA-templated transcription;GO:0010468 regulation of gene expression;GO:0048512 circadian behavior", "synthesized_glycan_count": 0, "hit_score": 2.1, "record_id": "Q9V6L0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VGK7-1", "uniprot_id": "ELP1_DROME", "mass": 142814.0, "length": 1252, "protein_name": "Elongator complex protein 1", "gene_name": "Elp1", "organism": "Fruit fly", "refseq_name": "elongator complex protein 1, isoform A", "refseq_ac": "NP_650098", "gene_names_uniprotkb": "Elp1; CG10535; D-elp1; Dmel\\CG10535; Dmel_CG10535; ELP1; elp1", "gene_names_refseq": "CG10535; D-elp1; Dmel\\CG10535; ELP1; Elp1; elp1", "protein_names_uniprotkb": "Elongator complex protein 1", "protein_names_refseq": "CG10535-PA; Elp1-PA; elongator complex protein 1, isoform A", "tax_id": 7227, "disease": "hemophagocytic lymphohistiocytosis (Disease Ontology:DOID:0050120); medulloblastoma (Disease Ontology:DOID:0050902); scoliosis (Disease Ontology:DOID:0060249); familial dysautonomia (Disease Ontology:DOID:11589); asthma (Disease Ontology:DOID:2841); kyphosis (Disease Ontology:DOID:4667)", "pathway": " (dme:Dmel_CG10535)", "pathway_count": 1, "publication_count": 15, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;18327897;25589440;26109356;26109357;29545390;36302967", "class_list": "", "function": "Component of the elongator complex which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). The elongator complex catalyzes formation of carboxymethyluridine in the wobble base at position 34 in tRNAs., [UniProtKB, UniProtKB, UniProtKB]; Component of the elongator complex, which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine) (PubMed:36302967). The elongator complex catalyzes formation of carboxymethyluridine in the wobble base at position 34 in tRNAs (PubMed:36302967). ELP1 binds to tRNA, mediating interaction of the elongator complex with tRNA (By similarity). Binding by the elongator complex stabilizes microtubules and promotes their growth (PubMed:36302967). This induces central spindle asymmetry, promoting polarized signaling endosome trafficking during asymmetric cell division and cell fate assignation of sensory organ precursor cells (PubMed:36302967). Involved in protein synthesis-dependent long-term memory formation, probably as part of the elongator complex (PubMed:29545390)., [UniProtKB, UniProtKB, UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 6, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q8MRJ9", "ec_number_list": "", "go_molecular_function": "GO:0000049 tRNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005819 spindle;GO:0005829 cytosol;GO:0005874 microtubule", "go_biological_process": "GO:0006417 regulation of translation;GO:0007616 long-term memory;GO:0002098 tRNA wobble uridine modification;GO:0002926 tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation;GO:0009047 dosage compensation by hyperactivation of X chromosome", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "Q9VGK7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VF36-1", "uniprot_id": "ACYP2_DROME", "mass": 11766.0, "length": 102, "protein_name": "Acylphosphatase-2", "gene_name": "Acyp2", "organism": "Fruit fly", "refseq_name": "acylphosphatase 2, isoform B", "refseq_ac": "NP_001262612", "gene_names_uniprotkb": "Acyp2; AcPDro2; CG18505; Dmel\\CG18505; Dmel_CG18505", "gene_names_refseq": "AcPDro2; Acyp2; CG18505; Dmel\\CG18505", "protein_names_uniprotkb": "Acylphosphatase-2; 3.6.1.7; AcPDro2; Acylphosphate phosphohydrolase 2", "protein_names_refseq": "Acyp2-PB; CG18505-PB; acylphosphatase 2, isoform B; acylphosphatase", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG18505)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;12560098;15159593;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q29QI6", "ec_number_list": "3.6.1.7", "go_molecular_function": "GO:0016787 hydrolase activity;GO:0003998 acylphosphatase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "Q9VF36-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VES1-1", "uniprot_id": "AR6P1_DROME", "mass": 22234.0, "length": 197, "protein_name": "ADP-ribosylation factor-like protein 6-interacting protein 1", "gene_name": "Arl6IP1", "organism": "Fruit fly", "refseq_name": "ADP-ribosylation factor-like 6 interacting protein 1, isoform B", "refseq_ac": "NP_001262647", "gene_names_uniprotkb": "Arl6IP1; ARL6IP1; Al6IP1; CG10326; Dmel\\CG10326; Dmel_CG10326", "gene_names_refseq": "ARL6IP1; Al6IP1; Arl6IP1; CG10326; Dmel\\CG10326", "protein_names_uniprotkb": "ADP-ribosylation factor-like protein 6-interacting protein 1", "protein_names_refseq": "ADP-ribosylation factor-like 6 interacting protein 1, isoform B; Arl6IP1-PB; CG10326-PB", "tax_id": 7227, "disease": "hereditary spastic paraplegia 61 (Disease Ontology:DOID:0110812); hereditary spastic paraplegia (Disease Ontology:DOID:2476)", "pathway": " (dme:Dmel_CG10326)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0016020 membrane;GO:0071782 endoplasmic reticulum tubular network;GO:0005783 endoplasmic reticulum", "go_biological_process": "GO:0007005 mitochondrion organization;GO:1990809 endoplasmic reticulum tubular network membrane organization", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "Q9VES1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VEC3-1", "uniprot_id": "ARP5_DROME", "mass": 75122.0, "length": 648, "protein_name": "Actin-related protein 5", "gene_name": "Arp5", "organism": "Fruit fly", "refseq_name": "Actin-related protein 5, isoform B", "refseq_ac": "NP_001262697", "gene_names_uniprotkb": "Arp5; CG7940; Dmel\\CG7940; Dmel_CG7940; dArp5", "gene_names_refseq": "Arp5; CG7940; Dmel\\CG7940; dArp5", "protein_names_uniprotkb": "Actin-related protein 5", "protein_names_refseq": "Actin-related protein 5, isoform B; Arp5-PB; CG7940-PB", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG7940); (R-DME-5689603); (R-DME-5696394)", "pathway_count": 3, "publication_count": 14, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;16618800;17569856;17569867;18327897;25589440;26109356;26109357", "class_list": "", "function": "Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair., [UniProtKB, UniProtKB]; Proposed core component of the chromatin remodeling Ino80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0030234 enzyme regulator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0031011 Ino80 complex", "go_biological_process": "GO:0006281 DNA repair;GO:0006310 DNA recombination;GO:0006338 chromatin remodeling;GO:0006351 DNA-templated transcription;GO:0006355 regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "Q9VEC3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VD44-1", "uniprot_id": "GLD2A_DROME", "mass": 147592.0, "length": 1364, "protein_name": "Poly(A) RNA polymerase gld-2 homolog A", "gene_name": "Gld2", "organism": "Fruit fly", "refseq_name": "GLD2 poly(A) polymerase, isoform C", "refseq_ac": "NP_001262829", "gene_names_uniprotkb": "Gld2; CG5732; Dm1; DmCG5732; DmGLD2; Dmel\\CG5732; Dmel_CG5732; GLD-2; GLD2; TUTase2", "gene_names_refseq": "CG5732; Dm1; DmCG5732; DmGLD2; Dmel\\CG5732; GLD-2; GLD2; Gld2; TUTase2", "protein_names_uniprotkb": "Poly(A) RNA polymerase gld-2 homolog A; 2.7.7.19; DmGLD2", "protein_names_refseq": "3' terminal uridylyl transferase 2; CG5732-PC; GLD2 poly(A) polymerase, isoform C; Gld2-PC", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG5732)", "pathway_count": 1, "publication_count": 14, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;18780789;25589440;26109356;26109357;40245499", "class_list": "", "function": "Cytoplasmic poly(A) RNA polymerase that adds successive AMP monomers to the 3'-end of specific RNAs, forming a poly(A) tail. In contrast to the canonical nuclear poly(A) RNA polymerase, it only adds poly(A) to selected cytoplasmic mRNAs. Required for formation of long term memory., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "B5RJK9;Q8MR77", "ec_number_list": "2.7.7.19", "go_molecular_function": "GO:0003723 RNA binding;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:1990817 poly(A) RNA polymerase activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0043005 neuron projection", "go_biological_process": "GO:0007616 long-term memory;GO:0031124 mRNA 3'-end processing;GO:0031123 RNA 3'-end processing", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "Q9VD44-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VHP0-1", "uniprot_id": "DDX3_DROME", "mass": 85081.0, "length": 798, "protein_name": "ATP-dependent RNA helicase bel", "gene_name": "bel", "organism": "Fruit fly", "refseq_name": "belle, isoform A", "refseq_ac": "NP_536783", "gene_names_uniprotkb": "bel; BELLE; BEL; Belle; Bel; CG9748; DDX3; DmRH6; Dmel\\CG9748; Dmel_CG9748; L3; anon-85Ab; cap; cg9748; l(3)85Ac; l(3)L3; l(3)L4740; l(3)S047110; l(3)S097074; ms(3)Pneo85A; ms(3)neo30; psg9", "gene_names_refseq": "BELLE; BEL; Belle; Bel; CG9748; DDX3; DmRH6; Dmel\\CG9748; L3; anon-85Ab; bel; cap; cg9748; l(3)85Ac; l(3)L3; l(3)L4740; l(3)S047110; l(3)S097074; ms(3)Pneo85A; ms(3)neo30; psg9", "protein_names_uniprotkb": "ATP-dependent RNA helicase bel; 3.6.4.13; Protein belle", "protein_names_refseq": "CG9748-PA; bel-PA; belle, isoform A; belle; capon; lethal (3) L4740; lethal (3) S047110", "tax_id": 7227, "disease": "Sertoli cell-only syndrome (Disease Ontology:DOID:0050457); syndromic X-linked intellectual disability (Disease Ontology:DOID:0060309); childhood medulloblastoma (Disease Ontology:DOID:3869); hepatocellular carcinoma (Disease Ontology:DOID:684); colorectal cancer (Disease Ontology:DOID:9256)", "pathway": " (dme:Dmel_CG9748); (R-DME-6798695)", "pathway_count": 2, "publication_count": 15, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;15572142;16110336;16531407;17569856;17569867;18327897;25589440;26109356;26109357", "class_list": "", "function": "ATP-dependent RNA helicase that is essential and required for cellular function, larval growth, and for male and female fertility. Also required for RNA interference (RNAi), double-stranded RNA induces potent and specific gene silencing, by acting downstream of dsRNA internalization. RNAi is mediated by the RNA-induced silencing complex (RISC), a sequence-specific, multicomponent nuclease that destroys or silences messenger RNAs homologous to the silencing trigger., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q8SXI8", "ec_number_list": "2.4.1.186;5.4.2.7;5.4.2.-;3.6.4.13;3.2.1.31;7.2.2.-;1.1.1.42;2.4.2.1;3.6.4.-;2.7.11.24;2.7.1.40;4.1.2.13;2.7.4.6;2.4.2.7;3.6.5.-;1.11.1.6;3.6.4.10;3.6.4.6;3.6.4.12;5.3.1.9;2.7.1.11;5.6.2.4;1.1.1.205;3.4.22.-;5.6.2.5;2.7.4.3;1.16.3.1;2.7.1.35;5.6.2.3;2.3.2.5;3.1.-.-;3.4.24.-;2.3.2.27;2.7.1.1;3.6.1.15;5.2.1.8;3.4.19.-;1.11.1.24;5.6.1.5;5.4.2.11;5.4.2.4;3.2.1.23;3.6.1.5;3.3.2.6;3.5.4.5;2.7.11.22;2.7.11.23;3.-.-.-;5.6.1.1;2.7.11.1;4.2.1.24;5.4.2.2;3.4.-.-;1.11.2.-;3.6.-.-;2.4.1.25;3.2.1.33;2.7.1.-;5.6.2.-;3.5.4.6;2.3.2.26", "go_molecular_function": "GO:0003729 mRNA binding;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0003724 RNA helicase activity;GO:0003723 RNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005829 cytosol;GO:0043025 neuronal cell body", "go_biological_process": "GO:0007283 spermatogenesis;GO:0010629 negative regulation of gene expression;GO:0030154 cell differentiation;GO:0035194 regulatory ncRNA-mediated post-transcriptional gene silencing;GO:0010468 regulation of gene expression", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "Q9VHP0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VGC3-1", "uniprot_id": "COG1_DROME", "mass": 99716.0, "length": 886, "protein_name": "Conserved oligomeric Golgi complex subunit 1", "gene_name": "Cog1", "organism": "Fruit fly", "refseq_name": "component of oligomeric golgi complex 1, isoform C", "refseq_ac": "NP_001262497", "gene_names_uniprotkb": "Cog1; CG4848; COG1; Dmel\\CG4848; Dmel_CG4848; cog1", "gene_names_refseq": "CG4848; COG1; Cog1; Dmel\\CG4848; cog1", "protein_names_uniprotkb": "Conserved oligomeric Golgi complex subunit 1; COG complex subunit 1; Component of oligomeric Golgi complex 1", "protein_names_refseq": "CG4848-PC; Cog1-PC; component of oligomeric golgi complex 1, isoform C", "tax_id": 7227, "disease": "congenital disorder of glycosylation type IIg (Disease Ontology:DOID:0070259)", "pathway": " (dme:Dmel_CG4848); (R-DME-6807878); (R-DME-6811438); (R-DME-6811440)", "pathway_count": 4, "publication_count": 13, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;18327897;25589440;26109356;26109357", "class_list": "", "function": "Required for normal Golgi function., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005794 Golgi apparatus;GO:0017119 Golgi transport complex", "go_biological_process": "GO:0015031 protein transport;GO:0007030 Golgi organization;GO:0000301 retrograde transport, vesicle recycling within Golgi;GO:0006891 intra-Golgi vesicle-mediated transport;GO:0007290 spermatid nucleus elongation", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "Q9VGC3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9Y0I1-1", "uniprot_id": "EAF3_DROME", "mass": 47194.0, "length": 424, "protein_name": "NuA4 complex subunit EAF3 homolog", "gene_name": "MRG15", "organism": "Fruit fly", "refseq_name": "MORF-related gene 15, isoform A", "refseq_ac": "NP_650442", "gene_names_uniprotkb": "MRG15; CG6363; DmMRG15; Dmel\\CG6363; Dmel_CG6363; Dmrg15; MRG-15; Mrg15; dMRG15; dMrg15; l(3)j6A3; mrg15", "gene_names_refseq": "CG6363; DmMRG15; Dmel\\CG6363; Dmrg15; MRG-15; MRG15; Mrg15; dMRG15; dMrg15; l(3)j6A3; mrg15", "protein_names_uniprotkb": "NuA4 complex subunit EAF3 homolog; Protein MRG15", "protein_names_refseq": "CG6363-PA; MORF-related gene 15, isoform A; MRG15-PA", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG6363)", "pathway_count": 1, "publication_count": 16, "publication_id_list": "10731132;11290425;12537568;12537569;12537572;12537573;12537574;15528408;16110336;17569856;17569867;18327897;25589440;26109356;26109357;32432549", "class_list": "", "function": "Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of histone H4 'Lys-12' (PubMed:32432549). Component of a SWR1-like complex that incorporates H2A.V genome-wide and specifically at active promoters, in an ATP-dependent manner (PubMed:32432549). Component of the Tip60 chromatin-remodeling complex that upon induction of DNA double-strand breaks, mediates the ATP-dependent exchange of unmodified histone H2AV for its phosphorylated and acetylated form H2AVK5acS138ph, leading to transcriptional regulation of selected genes by chromatin remodeling (PubMed:15528408)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 7, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "Q9VF99", "ec_number_list": "", "go_molecular_function": "GO:0003682 chromatin binding;GO:0030234 enzyme regulator activity;GO:1990889 histone H4K20me3 reader activity", "go_cellular_component": "GO:0005634 nucleus;GO:0035267 NuA4 histone acetyltransferase complex;GO:0035097 histone methyltransferase complex;GO:0000123 histone acetyltransferase complex;GO:0005694 chromosome", "go_biological_process": "GO:0006281 DNA repair;GO:0006338 chromatin remodeling;GO:0006351 DNA-templated transcription;GO:0010628 positive regulation of gene expression;GO:0045893 positive regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "Q9Y0I1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VEI9-1", "uniprot_id": "HMX_DROME", "mass": 62609.0, "length": 592, "protein_name": "Homeobox protein Hmx", "gene_name": "Hmx", "organism": "Fruit fly", "refseq_name": "H6-like-homeobox, isoform E", "refseq_ac": "NP_001287376", "gene_names_uniprotkb": "Hmx; CG18139; CG34419; CG43748; CG5829; CG5832; DHmx; Dmel\\CG43748; Dmel_CG43748; hmx", "gene_names_refseq": "CG18139; CG34419; CG43748; CG5829; CG5832; DHmx; Dmel\\CG43748; Hmx; hmx", "protein_names_uniprotkb": "Homeobox protein Hmx; DHmx", "protein_names_refseq": "CG43748-PE; H6-like-homeobox, isoform E; Hmx-PE", "tax_id": 7227, "disease": "oculoauricular syndrome (Disease Ontology:DOID:0060482)", "pathway": " (dme:Dmel_CG43748)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "10731132;11091080;12537568;12537572;12537573;12537574;15363417;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "Transcription factor involved in specification of neuronal cell types., [UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "A4IJ52;Q0IGR0", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0007399 nervous system development;GO:0030154 cell differentiation;GO:0045892 negative regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "Q9VEI9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VBW6-1", "uniprot_id": "DAN_DROME", "mass": 71914.0, "length": 678, "protein_name": "Protein distal antenna", "gene_name": "dan", "organism": "Fruit fly", "refseq_name": "distal antenna, isoform C", "refseq_ac": "NP_001262949", "gene_names_uniprotkb": "dan; CG11849; Dan; Dmel\\CG11849; Dmel_CG11849; fer", "gene_names_refseq": "CG11849; Dan; Dmel\\CG11849; dan; fer", "protein_names_uniprotkb": "Protein distal antenna", "protein_names_refseq": "CG11849-PC; dan-PC; distal antenna, isoform C; fernandez; tintin", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG11849)", "pathway_count": 1, "publication_count": 15, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;12571108;16110336;17493605;17569856;17569867;18327897;25589440;26109356;26109357", "class_list": "", "function": "Probable transcription factor with a role in the retinal determination (RD) network. Regulates ato expression and is required for normal R8 induction and differentiation. Danr appears to repress Dan expression, but Dan is required for Danr expression anterior to the morphogenetic furrow (MF). Dan and Danr lie downstream of so and require dac function for highest levels of expression. Contributes to differentiation of antenna-specific characteristics; effector gene that acts downstream of homothorax (hth), Distal-less (Dll), cut (ct) and spineless (ss) genes to control differentiation of distal antennal structures., [UniProtKB, PubMed, PubMed, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q960P9", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0003700 DNA-binding transcription factor activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0048749 compound eye development;GO:0006351 DNA-templated transcription;GO:0006355 regulation of DNA-templated transcription;GO:0007379 segment specification;GO:0007469 antennal development", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "Q9VBW6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VA73-1", "uniprot_id": "CMC_DROME", "mass": 76754.0, "length": 695, "protein_name": "Electrogenic aspartate/glutamate antiporter Aralar, mitochondrial", "gene_name": "Aralar", "organism": "Fruit fly", "refseq_name": "aralar1, isoform E", "refseq_ac": "NP_001247368", "gene_names_uniprotkb": "Aralar; AGC; Aralar1; BcDNA:GH07418; CABP1; CG2139; DmAralar; Dmel\\CG2139; Dmel_CG2139; aralar1; aralar", "gene_names_refseq": "Aralar1; Aralar; BcDNA:GH07418; CABP1; CG2139; DmAralar; Dmel\\CG2139; aralar1; aralar", "protein_names_uniprotkb": "Electrogenic aspartate/glutamate antiporter Aralar, mitochondrial; Mitochondrial aspartate/glutamate carrier protein Aralar", "protein_names_refseq": "Aralar1; CG2139-PE; aralar1, isoform E; aralar1-PE", "tax_id": 7227, "disease": "Asperger syndrome (Disease Ontology:DOID:0050432); fetal alcohol spectrum disorder (Disease Ontology:DOID:0050696); autism spectrum disorder (Disease Ontology:DOID:0060041); neonatal-onset type II citrullinemia (Disease Ontology:DOID:0070341); adult-onset type II citrullinemia (Disease Ontology:DOID:0070342); developmental and epileptic encephalopathy 39 (Disease Ontology:DOID:0080349); autistic disorder (Disease Ontology:DOID:12849); intrahepatic cholestasis (Disease Ontology:DOID:1852); common bile duct disease (Disease Ontology:DOID:4137); citrullinemia (Disease Ontology:DOID:9273)", "pathway": " (dme:Dmel_CG2139); (R-DME-8963693); (R-DME-9856872)", "pathway_count": 3, "publication_count": 16, "publication_id_list": "10642534;10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357;32200800;33497735;38945283", "class_list": "", "function": "Mitochondrial electrogenic aspartate/glutamate antiporter that favors efflux of aspartate and entry of glutamate and proton within the mitochondria as part of the malate-aspartate shuttle (PubMed:33497735). Also mediates the exchange of L-cysteinesulfinate (3-sulfino-L-alanine) for L-glutamate (PubMed:33497735). Necessary for gamma-aminobutyric acid (GABA) uptake in brain mitochondria in response to increased mitochondrial membrane polarization; does not possess detectable GABA transport activity but role may be indirect (PubMed:32200800, PubMed:38945283)., [UniProtKB, PubMed, PubMed, PubMed]; Possesses transport activity towards L-aspartate, L-glutamate and L-cysteinesulfinate (3-sulfino-L-alanine) (PubMed:33497735). L-glutamine transport activity is undetectable (PubMed:32200800, PubMed:38945283). GABA transport activity is undetectable (PubMed:38945283)., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 4, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 10, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A0B4K6V1;A4V3N6;Q95TN5;Q9U5V8;Q9VA72;Q9VA74", "ec_number_list": "", "go_molecular_function": "GO:0015495 gamma-aminobutyric acid:proton symporter activity;GO:0042802 identical protein binding;GO:0005509 calcium ion binding;GO:0005313 L-glutamate transmembrane transporter activity;GO:0015183 L-aspartate transmembrane transporter activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0006094 gluconeogenesis;GO:0015812 gamma-aminobutyric acid transport;GO:0015810 aspartate transmembrane transport;GO:0015813 L-glutamate transmembrane transport;GO:0043490 malate-aspartate shuttle", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "Q9VA73-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9V979-1", "uniprot_id": "CP6U1_DROME", "mass": 55508.0, "length": 488, "protein_name": "Probable cytochrome P450 6u1", "gene_name": "Cyp6u1", "organism": "Fruit fly", "refseq_name": "cytochrome P450 6u1, isoform B", "refseq_ac": "NP_001286149", "gene_names_uniprotkb": "Cyp6u1; 6u1; CG3567; Dmel\\CG3567; Dmel_CG3567", "gene_names_refseq": "6u1; CG3567; Cyp6u1; Dmel\\CG3567", "protein_names_uniprotkb": "Probable cytochrome P450 6u1; 1.14.-.-; CYPVIU1", "protein_names_refseq": "CG3567-PB; Cyp6u1-PB; cytochrome P450 6u1, isoform B; cytochrome P450", "tax_id": 7227, "disease": "prostate cancer (Disease Ontology:DOID:10283); Alzheimer's disease (Disease Ontology:DOID:10652)", "pathway": " (dme:Dmel_CG3567)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q8T9B9", "ec_number_list": "", "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0004497 monooxygenase activity;GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "Q9V979-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9V9L1-1", "uniprot_id": "CP6W1_DROME", "mass": 59321.0, "length": 514, "protein_name": "Probable cytochrome P450 6w1", "gene_name": "Cyp6w1", "organism": "Fruit fly", "refseq_name": "cytochrome P450 6w1, isoform B", "refseq_ac": "NP_001286145", "gene_names_uniprotkb": "Cyp6w1; 6w1; AntP450; CG8345; CYP6W1; CYP6w1; Cyp6W1; Dmel\\CG8345; Dmel_CG8345", "gene_names_refseq": "6w1; AntP450; CG8345; CYP6W1; CYP6w1; Cyp6W1; Cyp6w1; Dmel\\CG8345", "protein_names_uniprotkb": "Probable cytochrome P450 6w1; 1.14.-.-; CYPVIW1", "protein_names_refseq": "CG8345-PB; Cyp6w1-PB; cytochrome P450 6w1, isoform B; cytochrome P450", "tax_id": 7227, "disease": "alcohol dependence (Disease Ontology:DOID:0050741); alcohol-associated liver disease (Disease Ontology:DOID:0070658); B-lymphoblastic leukemia/lymphoma (Disease Ontology:DOID:0080630); prostate cancer (Disease Ontology:DOID:10283); Alzheimer's disease (Disease Ontology:DOID:10652); essential hypertension (Disease Ontology:DOID:10825); cholestasis (Disease Ontology:DOID:13580); depressive disorder (Disease Ontology:DOID:1596); anxiety disorder (Disease Ontology:DOID:2030); familial Mediterranean fever (Disease Ontology:DOID:2987); liver cirrhosis (Disease Ontology:DOID:5082); oral submucous fibrosis (Disease Ontology:DOID:5773); end stage renal disease (Disease Ontology:DOID:783); chronic myeloid leukemia (Disease Ontology:DOID:8552); acute lymphoblastic leukemia (Disease Ontology:DOID:9952)", "pathway": " (dme:Dmel_CG8345)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 15, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0004497 monooxygenase activity;GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0046680 response to DDT;GO:0046701 insecticide catabolic process", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "Q9V9L1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9V770-1", "uniprot_id": "C6A17_DROME", "mass": 58208.0, "length": 501, "protein_name": "Probable cytochrome P450 6a17", "gene_name": "Cyp6a17", "organism": "Fruit fly", "refseq_name": "cytochrome P450 6a17, isoform B", "refseq_ac": "NP_001286433", "gene_names_uniprotkb": "Cyp6a17; 61D6S; 6a17; CG10241; Cyp6A17; Dmel\\CG10241; Dmel_CG10241; ESTS:61D6S; cyp6a17; temp", "gene_names_refseq": "61D6S; 6a17; CG10241; Cyp6A17; Cyp6a17; Dmel\\CG10241; ESTS:61D6S; cyp6a17; temp", "protein_names_uniprotkb": "Probable cytochrome P450 6a17; 1.14.-.-; CYPVIA17", "protein_names_refseq": "CG10241-PB; Cyp6a17-PB; cytochrome P450 6a17, isoform B; cytochrome P450-6a17; cytochrome P450", "tax_id": 7227, "disease": "alcohol dependence (Disease Ontology:DOID:0050741); alcohol-associated liver disease (Disease Ontology:DOID:0070658); B-lymphoblastic leukemia/lymphoma (Disease Ontology:DOID:0080630); prostate cancer (Disease Ontology:DOID:10283); Alzheimer's disease (Disease Ontology:DOID:10652); essential hypertension (Disease Ontology:DOID:10825); cholestasis (Disease Ontology:DOID:13580); depressive disorder (Disease Ontology:DOID:1596); anxiety disorder (Disease Ontology:DOID:2030); familial Mediterranean fever (Disease Ontology:DOID:2987); liver cirrhosis (Disease Ontology:DOID:5082); oral submucous fibrosis (Disease Ontology:DOID:5773); end stage renal disease (Disease Ontology:DOID:783); chronic myeloid leukemia (Disease Ontology:DOID:8552); acute lymphoblastic leukemia (Disease Ontology:DOID:9952)", "pathway": " (dme:Dmel_CG10241)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 15, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0004497 monooxygenase activity;GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0040040 thermosensory behavior", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9V770-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9W2A3-1", "uniprot_id": "Q9W2A3_DROME", "mass": 48603.0, "length": 413, "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG13501", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform A", "refseq_ac": "NP_611631", "gene_names_uniprotkb": "Dmel\\CG13501; CG13501; Dmel_CG13501", "gene_names_refseq": "CG13501; Dmel\\CG13501", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "CG13501-PA; uncharacterized protein, isoform A", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG13501)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9W2A3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9V769-1", "uniprot_id": "C6A22_DROME", "mass": 57278.0, "length": 499, "protein_name": "Cytochrome P450 6a22", "gene_name": "Cyp6a22", "organism": "Fruit fly", "refseq_name": "cytochrome P450 6a22, isoform B", "refseq_ac": "NP_001286431", "gene_names_uniprotkb": "Cyp6a22; 6a22; BF6-2; CG10240; CYT-P450-RBF6-2; Cyt-P450-rBF6-2; Dmel\\CG10240; Dmel_CG10240; P-450; P450; cyp6a22", "gene_names_refseq": "6a22; BF6-2; CG10240; Cyp6a22; Cyt-P450-rBF6-2; Dmel\\CG10240; P-450; P450; cyp6a22", "protein_names_uniprotkb": "Cytochrome P450 6a22; 1.14.-.-; CYPVIA22", "protein_names_refseq": "CG10240-PB; Cyp6a22-PB; cytochrome P450 6a22, isoform B; cytochrome P450 related BF6-2; cytochrome P450", "tax_id": 7227, "disease": "alcohol dependence (Disease Ontology:DOID:0050741); prostate cancer (Disease Ontology:DOID:10283); Alzheimer's disease (Disease Ontology:DOID:10652); cholestasis (Disease Ontology:DOID:13580); depressive disorder (Disease Ontology:DOID:1596); anxiety disorder (Disease Ontology:DOID:2030); liver cirrhosis (Disease Ontology:DOID:5082); end stage renal disease (Disease Ontology:DOID:783)", "pathway": " (dme:Dmel_CG10240)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357;8973362", "class_list": "", "function": "May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 8, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q27592", "ec_number_list": "", "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0004497 monooxygenase activity;GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "Q9V769-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VN19-1", "uniprot_id": "GET4_DROME", "mass": 38490.0, "length": 339, "protein_name": "Golgi to ER traffic protein 4 homolog", "gene_name": "Dmel\\CG9853", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform B", "refseq_ac": "NP_001097680", "gene_names_uniprotkb": "Dmel\\CG9853; BEST:LD21829; CG41469; CG9853; Dmel_CG9853; Get4", "gene_names_refseq": "BEST:LD21829; CG41469; CG9853; Dmel\\CG9853; Get4", "protein_names_uniprotkb": "Golgi to ER traffic protein 4 homolog", "protein_names_refseq": "CG9853-PB; uncharacterized protein, isoform B", "tax_id": 7227, "disease": "congenital disorder of glycosylation type IIy (Disease Ontology:DOID:0051052)", "pathway": " (dme:Dmel_CG9853)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "May play a role in insertion of tail-anchored proteins into the endoplasmic reticulum membrane., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0140597 protein carrier chaperone", "go_cellular_component": "GO:0005829 cytosol;GO:0071818 BAT3 complex", "go_biological_process": "GO:0045048 protein insertion into ER membrane", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "Q9VN19-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VI60-1", "uniprot_id": "ENY2B_DROME", "mass": 10829.0, "length": 95, "protein_name": "Enhancer of yellow 2b transcription factor", "gene_name": "e(y)2b", "organism": "Fruit fly", "refseq_name": "enhancer of yellow 2b, isoform B", "refseq_ac": "NP_001287204", "gene_names_uniprotkb": "e(y)2b; CG14612; Dmel\\CG14612; Dmel_CG14612; e(y)2", "gene_names_refseq": "CG14612; Dmel\\CG14612; e(y)2b", "protein_names_uniprotkb": "Enhancer of yellow 2b transcription factor; Testis-specific e(y)2 paralog", "protein_names_refseq": "CG14612-PB; e(y)2b-PB; enhancer of yellow 2b, isoform B", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG14612)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "10731132;11438676;12537568;12537572;12537573;12537574;16110336;16314324;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "Involved in mRNA export coupled transcription activation by association with both the AMEX and the SAGA complexes. The SAGA complex is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates histone H2B. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Involved in transcription elongation by recruiting the THO complex onto nascent mRNA. The AMEX complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). AMEX participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery., [UniProtKB, HAMAP]; Testis-specific paralog of the ubiquitously expressed transcription and mRNA export factor e(y)2. Cannot functionally replace e(y)2., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0043035 chromatin insulator sequence binding;GO:0003682 chromatin binding;GO:0003713 transcription coactivator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005643 nuclear pore;GO:0005737 cytoplasm;GO:0071819 DUBm complex;GO:0070390 transcription export complex 2", "go_biological_process": "GO:0016973 poly(A)+ mRNA export from nucleus;GO:0006357 regulation of transcription by RNA polymerase II;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0006368 transcription elongation by RNA polymerase II;GO:0006406 mRNA export from nucleus", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "Q9VI60-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VNH1-1", "uniprot_id": "BN3D2_DROME", "mass": 34724.0, "length": 300, "protein_name": "U6 snRNA methylphosphate capping enzyme Amus", "gene_name": "Amus", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform B", "refseq_ac": "NP_001287185", "gene_names_uniprotkb": "Amus; BCDIN3D; CG1239; Dmel\\CG1239; Dmel_CG1239; cg1239", "gene_names_refseq": "BCDIN3D; CG1239; Dmel\\CG1239; cg1239", "protein_names_uniprotkb": "U6 snRNA methylphosphate capping enzyme Amus; 2.1.1.-; Protein another methylase of U6", "protein_names_refseq": "CG1239-PB; uncharacterized protein, isoform B", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG1239)", "pathway_count": 1, "publication_count": 15, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;16951084;17569856;17569867;19126864;25589440;26109356;26109357;31145769;38100593", "class_list": "", "function": "Probable S-adenosyl-L-methionine-dependent methyltransferase that binds and stabilizes U6 snRNA, probably by adding a methylphosphate cap at its 5'-end (PubMed:38100593). Required for U6 stability, but not stability of 7SK snRNAs, other miRNAs or tRNAs (PubMed:38100593). U6 stabilization is required for efficient pre-mRNA splicing (PubMed:38100593). Essential for organismal and germline development (PubMed:38100593)., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 3, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0ANN6;A0ANP4;C0MJ20;C0MJ21", "ec_number_list": "", "go_molecular_function": "GO:0008171 O-methyltransferase activity;GO:0017069 snRNA binding;GO:0008173 RNA methyltransferase activity;GO:0017070 U6 snRNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0040031 snRNA modification;GO:0106349 snRNA methylation;GO:0032259 methylation", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "Q9VNH1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VHP4-1", "uniprot_id": "CP313_DROME", "mass": 58222.0, "length": 502, "protein_name": "Probable cytochrome P450 313b1", "gene_name": "Cyp313b1", "organism": "Fruit fly", "refseq_name": "cytochrome P450 313b1, isoform B", "refseq_ac": "NP_001287239", "gene_names_uniprotkb": "Cyp313b1; 313b1; CG9716; CYP313B1; Dmel\\CG9716; Dmel_CG9716", "gene_names_refseq": "313b1; CG9716; CYP313B1; Cyp313b1; Dmel\\CG9716", "protein_names_uniprotkb": "Probable cytochrome P450 313b1; 1.14.-.-; CYPCCCXIIIB1", "protein_names_refseq": "CG9716-PB; Cyp313b1-PB; cytochrome P450 313b1, isoform B", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG9716)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q8SZA9", "ec_number_list": "", "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0004497 monooxygenase activity;GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "Q9VHP4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VHG5-1", "uniprot_id": "Q9VHG5_DROME", "mass": 27717.0, "length": 242, "protein_name": "Insulator binding factor 1, isoform A", "gene_name": "Ibf1", "organism": "Fruit fly", "refseq_name": "insulator binding factor 1, isoform A", "refseq_ac": "NP_649875", "gene_names_uniprotkb": "Ibf1; CG8436; Dmel\\CG8436; Dmel_CG8436; Ibf", "gene_names_refseq": "CG8436; Dmel\\CG8436; Ibf1; Ibf", "protein_names_uniprotkb": "Insulator binding factor 1, isoform A", "protein_names_refseq": "CG8436-PA; Ibf1-PA; insulator binding factor 1, isoform A", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG8436)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0043035 chromatin insulator sequence binding;GO:0043565 sequence-specific DNA binding;GO:0046982 protein heterodimerization activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0033696 heterochromatin boundary formation", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VHG5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9V8G0-1", "uniprot_id": "BM03_DROME", "mass": 4100.0, "length": 39, "protein_name": "Bomanin Short 3", "gene_name": "BomS3", "organism": "Fruit fly", "refseq_name": "bomanin short 3, isoform B", "refseq_ac": "NP_001286569", "gene_names_uniprotkb": "BomS3; BcDNA:RH58911; Bom3; CG16844; CT37419; DIM 3; DIM3; Dmel\\CG16844; Dmel_CG16844; IM3; im3", "gene_names_refseq": "BcDNA:RH58911; Bom3; BomS3; CG16844; CT37419; DIM 3; DIM3; Dmel\\CG16844; IM3; im3", "protein_names_uniprotkb": "Bomanin Short 3; Bomanin-3; DIM-3; DIM3; Immune-induced peptide 3", "protein_names_refseq": "BomS3-PB; CG16844-PB; bomanin 3; bomanin S3; bomanin short 3, isoform B; immune induced molecule 3", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG16844)", "pathway_count": 1, "publication_count": 14, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;25915418;26109356;26109357;29920489;9736738", "class_list": "", "function": "Secreted immune-induced peptide induced by Toll signaling (PubMed:29920489). Has a role in resistance bacterial and fungal infections (PubMed:25915418, PubMed:29920489). The strength of antimicrobial activity appears to correlate with the overall level of expression (PubMed:29920489). Has no activity against the fungus C.glabrata in vitro (PubMed:29920489)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005615 extracellular space;GO:0005576 extracellular region", "go_biological_process": "GO:0019731 antibacterial humoral response;GO:0045087 innate immune response;GO:0050830 defense response to Gram-positive bacterium;GO:0009617 response to bacterium;GO:0010046 response to mycotoxin", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "Q9V8G0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VGP0-1", "uniprot_id": "DTD_DROME", "mass": 17889.0, "length": 158, "protein_name": "D-aminoacyl-tRNA deacylase", "gene_name": "Dtd", "organism": "Fruit fly", "refseq_name": "D-aminoacyl-tRNA deacylase, isoform B", "refseq_ac": "NP_650072", "gene_names_uniprotkb": "Dtd; CG18643; DTD; DmDTD; Dmel\\CG18643; Dmel_CG18643", "gene_names_refseq": "CG18643; DTD; DmDTD; Dmel\\CG18643; Dtd", "protein_names_uniprotkb": "D-aminoacyl-tRNA deacylase; 3.1.1.96; Gly-tRNA(Ala) deacylase; Gly-tRNA(Gly) deacylase", "protein_names_refseq": "CG18643-PB; D-aminoacyl-tRNA deacylase, isoform B; Dtd-PB", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG18643)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357;27224426;28362257", "class_list": "", "function": "An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs (By similarity). Hydrolyzes correctly charged, achiral, glycyl-tRNA(Gly) (PubMed:27224426). Deacylates mischarged endogenous and E.coli glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS (PubMed:28362257). Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site (By similarity). By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality (By similarity)., [UniProtKB, PubMed, PubMed, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q4V4U7;Q4V6L2", "ec_number_list": "3.1.1.96", "go_molecular_function": "GO:0051500 D-tyrosyl-tRNA(Tyr) deacylase activity;GO:0000049 tRNA binding;GO:0106026 Gly-tRNA(Ala) deacylase activity;GO:0051499 D-aminoacyl-tRNA deacylase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0006399 tRNA metabolic process", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "Q9VGP0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VFG8-1", "uniprot_id": "KIBRA_DROME", "mass": 144350.0, "length": 1288, "protein_name": "Protein kibra", "gene_name": "kibra", "organism": "Fruit fly", "refseq_name": "kibra, isoform A", "refseq_ac": "NP_001034055", "gene_names_uniprotkb": "kibra; CG12600; CG33967; CG7552; DmKibra; Dmel\\CG33967; Dmel_CG33967; Kbr; Kibra; Kib; ORE-2; RE26350; WWC1; kbr; kib; l(3)02404; l(3)j5C3; l(3)neo42", "gene_names_refseq": "CG12600; CG33967; CG7552; DmKibra; Dmel\\CG33967; Kbr; Kibra; Kib; ORE-2; RE26350; WWC1; kbr; kibra; kib; l(3)02404; l(3)j5C3; l(3)neo42", "protein_names_uniprotkb": "Protein kibra", "protein_names_refseq": "CG33967-PA; kibra ortholog; kibra, isoform A; kibra-PA; lethal (3) neo42", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG33967); (R-DME-2028269)", "pathway_count": 2, "publication_count": 16, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;18327897;20159598;20159599;20159600;25589440;26109356;26109357", "class_list": "", "function": "Regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein Hippo (Hpo), in complex with its regulatory protein Salvador (Sav), phosphorylates and activates Warts (Wts) in complex with its regulatory protein Mats, which in turn phosphorylates and inactivates the Yorkie (Yki) oncoprotein. Kibra acts synergistically along with Ex and Mer to regulate the Hippo signaling pathway., [UniProtKB, UniProtKB, UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 4, "predicted_n_glycosites": 0, "predicted_o_glycosites": 4, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "Q5BIC8", "ec_number_list": "", "go_molecular_function": "GO:0060090 molecular adaptor activity;GO:0019900 kinase binding", "go_cellular_component": "GO:0098592 cytoplasmic side of apical plasma membrane;GO:0045179 apical cortex;GO:0005737 cytoplasm;GO:0016324 apical plasma membrane;GO:0036375 Kibra-Ex-Mer complex", "go_biological_process": "GO:0046621 negative regulation of organ growth;GO:0035330 regulation of hippo signaling;GO:0006351 DNA-templated transcription;GO:0016477 cell migration;GO:0043065 positive regulation of apoptotic process", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "Q9VFG8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VC61-1", "uniprot_id": "CRERF_DROME", "mass": 82263.0, "length": 755, "protein_name": "Protein CREBRF homolog", "gene_name": "REPTOR", "organism": "Fruit fly", "refseq_name": "repressed by TOR, isoform E", "refseq_ac": "NP_001036752", "gene_names_uniprotkb": "REPTOR; CG13624; DM23; DM24; Dmel\\CG13624; Dmel_CG13624; Reptor; anon-WO0153538.65; reptor", "gene_names_refseq": "CG13624; DM23; DM24; Dmel\\CG13624; REPTOR; Reptor; anon-WO0153538.65; reptor", "protein_names_uniprotkb": "Protein CREBRF homolog; Protein Repressed by Tor", "protein_names_refseq": "CG13624-PE; REPTOR-PE; repressed by TOR, isoform E; repressed by TOR", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG13624)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;25589440;25920570;26109356;26109357", "class_list": "", "function": "Transcriptional regulator that acts in the TORC1 signaling pathway to regulate energy homeostasis and promote survival during nutrient deprivation. Interacts with REPTOR to form a transcriptional activator complex that functions downstream of TORC1 to up-regulate the expression of most target genes induced by TORC1 inhibition. In the complex, acts as the transcriptional activator. Under normal conditions TORC1 is active, inhibiting the formation of the REPTOR/REPTOR-BP complex by phosphorylating REPTOR and mediates its cytoplasmic retention by forming a docking site for 14-3-3 proteins. Upon TORC1 inhibition resulting from nutrient stress, REPTOR is recruited into the nucleus where it interacts with REPTOR-BP and together they maintain organismal metabolism by activating the expression of target stress response genes including those involved in glycogenesis and triglyceride biosynthesis. The complex also appears to negatively regulate some aspects of TORC1-dependent larval growth., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 9, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q0KI17;Q8T9A9", "ec_number_list": "", "go_molecular_function": "GO:0046982 protein heterodimerization activity;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003700 DNA-binding transcription factor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0005694 chromosome", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0042594 response to starvation;GO:0045893 positive regulation of DNA-templated transcription;GO:0038202 TORC1 signaling", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "Q9VC61-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VC44-1", "uniprot_id": "ALLS_DROME", "mass": 16852.0, "length": 151, "protein_name": "Allatostatin-A", "gene_name": "AstA", "organism": "Fruit fly", "refseq_name": "allatostatin A, isoform B", "refseq_ac": "NP_001287511", "gene_names_uniprotkb": "AstA; ALLS; ASA; AST-1; AST-3; AST-4; AST-A; AST; AS; Allatostatin A1; Allatostatin A2; Allatostatin A3; Allatostatin A4; Ast-A; AstA-1; AstA-2; AstA-3; AstA-4; AstA1; AstA2; AstA4; Ast; BcDNA:RE16553; CG13633; DAP-A; DAP; DST-1A; DST-2A; DST-3A; DST-4A; Dmel\\CG13633; Dmel_CG13633; Drm-AST-1; Drm-AST-2; Drm-AST-3; Drm-AST-4; Drm-AST-A; ast", "gene_names_refseq": "ALLS; ASA; AST-1; AST-3; AST-4; AST-A; AST; AS; Allatostatin A1; Allatostatin A2; Allatostatin A3; Allatostatin A4; Ast-A; AstA-1; AstA-2; AstA-3; AstA-4; AstA1; AstA2; AstA4; AstA; Ast; BcDNA:RE16553; CG13633; DAP-A; DAP; DST-1A; DST-2A; DST-3A; DST-4A; Dmel\\CG13633; Drm-AST-1; Drm-AST-2; Drm-AST-3; Drm-AST-4; Drm-AST-A; ast", "protein_names_uniprotkb": "Allatostatin-A; AST-A1; AST-A2(1-11); AST-A2(14-21); AST-A3; AST-A4; Allatostatins Ast", "protein_names_refseq": "AstA-PB; CG13633-PB; Drostatin-A1; Drostatin-A3; Drostatin-A4; FGLa-type allatostatin; allatostatin A, isoform B; allatostatin A-1; allatostatin Diploptera-type; allatostatin-A-like; allatostatin-A4; drostatin-A2", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG13633)", "pathway_count": 1, "publication_count": 15, "publication_id_list": "10731132;10891383;12171930;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;21214272;25589440;26109356;26109357", "class_list": "", "function": "May act as a neurotransmitter or neuromodulator., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9NB67", "ec_number_list": "", "go_molecular_function": "GO:0005102 signaling receptor binding;GO:0005184 neuropeptide hormone activity;GO:0005179 hormone activity;GO:0071855 neuropeptide receptor binding", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0007218 neuropeptide signaling pathway;GO:0045968 negative regulation of juvenile hormone biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "Q9VC44-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VFD5-1", "uniprot_id": "FEM1A_DROME", "mass": 73786.0, "length": 664, "protein_name": "Protein fem-1 homolog CG6966", "gene_name": "BcDNA:AT05246", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform B", "refseq_ac": "NP_001097796", "gene_names_uniprotkb": "BcDNA:AT05246; CG6966; Dmel\\CG6966; Dmel_CG6966; dFEM1A", "gene_names_refseq": "BcDNA:AT05246; CG6966; Dmel\\CG6966; dFEM1A", "protein_names_uniprotkb": "Protein fem-1 homolog CG6966", "protein_names_refseq": "CG6966-PB; uncharacterized protein, isoform B", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG6966); (R-DME-8951664); (R-DME-983168)", "pathway_count": 3, "publication_count": 12, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "Substrate-recognition component of a Cul2-RING (CRL2) E3 ubiquitin-protein ligase complex of the DesCEND (destruction via C-end degrons) pathway, which recognizes a C-degron located at the extreme C terminus of target proteins, leading to their ubiquitination and degradation. The C-degron recognized by the DesCEND pathway is usually a motif of less than ten residues and can be present in full-length proteins, truncated proteins or proteolytically cleaved forms., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q8IG97;Q8T4I2", "ec_number_list": "", "go_molecular_function": "GO:1990756 ubiquitin-like ligase-substrate adaptor activity", "go_cellular_component": "GO:0000151 ubiquitin ligase complex", "go_biological_process": "GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0016567 protein ubiquitination", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "Q9VFD5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VQ56-1", "uniprot_id": "ERM_DROME", "mass": 66441.0, "length": 611, "protein_name": "Fez family zinc finger protein erm", "gene_name": "erm", "organism": "Fruit fly", "refseq_name": "earmuff, isoform A", "refseq_ac": "NP_608631", "gene_names_uniprotkb": "erm; CG31670; CG7312; Dfezf; Dmel\\CG31670; Dmel_CG31670; Erm; dFezf; dfezl", "gene_names_refseq": "CG31670; CG7312; Dfezf; Dmel\\CG31670; Erm; dFezf; dfezl; erm", "protein_names_uniprotkb": "Fez family zinc finger protein erm; Earmuff", "protein_names_refseq": "CG31670-PA; earmuff, isoform A; erm-PA", "tax_id": 7227, "disease": "hypogonadotropic hypogonadism 22 with or without anosmia (Disease Ontology:DOID:0090081)", "pathway": " (dme:Dmel_CG31670)", "pathway_count": 1, "publication_count": 21, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;18621688;20152183;24550111;24618901;25589440;26109356;26109357;27151950;27510969;28245922;28899667;29513217", "class_list": "", "function": "Zinc-finger transcriptional repressor (PubMed:24550111, PubMed:24618901, PubMed:28245922). In larval brain, involved in the maintenance of cell fate of intermediate neural progenitors (INPs) that derive from type II neuroblasts (PubMed:20152183, PubMed:24618901, PubMed:27151950, PubMed:27510969, PubMed:28245922, PubMed:28899667). Restricts INP developmental potential and dedifferentiation by interacting with HDAC3 and the chromatin remodeling Brahma-associated protein (BAP) complex (PubMed:24550111, PubMed:24618901, PubMed:27151950, PubMed:28245922, PubMed:28899667). Restricts INP proliferation by regulating neuroblast specific factors such as prospero, pnt and grh, and by antagonizing the function of self-renewal factors, such as klu, dpn and E(spl)mgamma-HLH (PubMed:20152183, PubMed:24550111, PubMed:28899667). In the optic lobe, essential for coordinating the innervation/ targeting of the L3 and R8 axons to the M3 layer of the medulla (PubMed:29513217). Early in medulla development, functions in parallel to CadN and Sema1a pathways to promote targeting of the L3 growth cones to the proximal domain of the outer medulla possibly by controlling the expression of various cell surface genes such as dpr1 and dpr17 which function in L3 growth cone targeting (PubMed:29513217). Then once L3 growth cones segregate into the developing M3 layer, it activates the expression of netrins NetA and NetB which act locally to promote the attachment of R8 growth cones within the M3 layer (PubMed:29513217)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q95SM6", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000976 transcription cis-regulatory region binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0043565 sequence-specific DNA binding;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0043025 neuronal cell body;GO:0044295 axonal growth cone", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0010628 positive regulation of gene expression;GO:0010629 negative regulation of gene expression;GO:0045666 positive regulation of neuron differentiation", "synthesized_glycan_count": 0, "hit_score": 2.2, "record_id": "Q9VQ56-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VS29-1", "uniprot_id": "DSCL_DROME", "mass": 227598.0, "length": 2074, "protein_name": "Cell adhesion molecule Dscam2", "gene_name": "Dscam2", "organism": "Fruit fly", "refseq_name": "down syndrome cell adhesion molecule 2, isoform I", "refseq_ac": "NP_001036588", "gene_names_uniprotkb": "Dscam2; BcDNA:AT03867; CG14828; CG17742; CG32387; CG32389; CG42256; CG8618; CG8619; CT14580; CT14584; CT34644; DSCAM; Dmel\\CG42256; Dmel_CG42256; Dscam-like", "gene_names_refseq": "BcDNA:AT03867; CG14828; CG17742; CG32387; CG32389; CG42256; CG8618; CG8619; CT14580; CT14584; CT34644; DSCAM; Dmel\\CG42256; Dscam-like; Dscam2", "protein_names_uniprotkb": "Cell adhesion molecule Dscam2; Down syndrome cell adhesion molecule-like protein Dscam2", "protein_names_refseq": "CG42256-PI; Dscam2-PI; down syndrome cell adhesion molecule 2, isoform I", "tax_id": 7227, "disease": "ocular motor apraxia, Cogan type (Disease Ontology:DOID:0080849); ocular motility disease (Disease Ontology:DOID:1279)", "pathway": " (dme:Dmel_CG42256); (R-DME-376172)", "pathway_count": 2, "publication_count": 13, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;14623821;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "Cell adhesion molecule., [UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "B7Z0C6;B7Z0C7;B7Z0C8;Q0E8H6;Q8MTB2;Q9VS28;Q9VS30", "ec_number_list": "", "go_molecular_function": "GO:0042802 identical protein binding;GO:0098632 cell-cell adhesion mediator activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0030424 axon;GO:0016020 membrane", "go_biological_process": "GO:0048812 neuron projection morphogenesis;GO:0007417 central nervous system development;GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007411 axon guidance;GO:0070593 dendrite self-avoidance", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "Q9VS29-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VNA8-1", "uniprot_id": "DONS_DROME", "mass": 63438.0, "length": 568, "protein_name": "Protein downstream neighbor of son homolog", "gene_name": "hd", "organism": "Fruit fly", "refseq_name": "humpty dumpty, isoform B", "refseq_ac": "NP_001303424", "gene_names_uniprotkb": "hd; CG2669; Dmel\\CG2669; Dmel_CG2669; fs(3)272-9; fs(3)272; l(3)82Ff; l(3)82Fk", "gene_names_refseq": "CG2669; Dmel\\CG2669; fs(3)272-9; fs(3)272; hd; l(3)82Ff; l(3)82Fk", "protein_names_uniprotkb": "Protein downstream neighbor of son homolog; Protein humpty dumpty", "protein_names_refseq": "CG2669-PB; female sterile(3)272-9; hd-PB; humpty dumpty, isoform B; lethal (3) 82Ff; lethal (3) 82Fk", "tax_id": 7227, "disease": "microcephaly, short stature, and limb abnormalities (Disease Ontology:DOID:0081431); microcephaly-micromelia syndrome (Disease Ontology:DOID:0081432); syndrome (Disease Ontology:DOID:225)", "pathway": " (dme:Dmel_CG2669)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;15854909;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "Essential for DNA amplification in the ovary and required for cell proliferation during development., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q540V6", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0051301 cell division;GO:0033260 nuclear DNA replication;GO:0007307 eggshell chorion gene amplification", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "Q9VNA8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VQI9-1", "uniprot_id": "AFFL_DROME", "mass": 180089.0, "length": 1673, "protein_name": "AF4/FMR2 family member lilli", "gene_name": "lilli", "organism": "Fruit fly", "refseq_name": "lilliputian, isoform D", "refseq_ac": "NP_001137772", "gene_names_uniprotkb": "lilli; 154454_at; 189Y; AFF4; BEST:GH09955; BcDNA:GM02019; CG8817; Dmel\\CG8817; Dmel_CG8817; Lilli; S(ls)4; SS2-1; SY2-1; Su(Raf)2A; Su(Raf)2a; dAFF4; dAFF; l(2)00632; l(2)23Cc; l(2)K00632; l(2)K07920; l(2)k07920; l(2)k16124", "gene_names_refseq": "154454_at; 189Y; AFF4; BEST:GH09955; BcDNA:GM02019; CG8817; Dmel\\CG8817; Lilli; S(ls)4; SS2-1; SY2-1; Su(Raf)2A; Su(Raf)2a; dAFF4; dAFF; l(2)00632; l(2)23Cc; l(2)K00632; l(2)K07920; l(2)k07920; l(2)k16124; lilli", "protein_names_uniprotkb": "AF4/FMR2 family member lilli; Protein lilliputian; Suppressor of Raf at 2A; Suppressor of sina 2-1", "protein_names_refseq": "CG8817-PD; liliputian; lilli-PD; lilliputian, isoform D; lilliputian; suppressor of GMR-sina 2-1", "tax_id": 7227, "disease": "X-linked intellectual developmental disorder 109 (Disease Ontology:DOID:0080984); KINSSHIP syndrome (Disease Ontology:DOID:0112383); skin melanoma (Disease Ontology:DOID:8923); colorectal cancer (Disease Ontology:DOID:9256); type 2 diabetes mellitus (Disease Ontology:DOID:9352)", "pathway": " (dme:Dmel_CG8817); (R-DME-112382); (R-DME-674695); (R-DME-75955)", "pathway_count": 4, "publication_count": 20, "publication_id_list": "10731132;11171403;11171404;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;18327897;22195968;25589440;26109356;26109357;33925313;8770593;8978055;9475739", "class_list": "", "function": "Has a role in transcriptional regulation. Acts in parallel with the Ras/MAPK and the PI3K/PKB pathways in the control of cell identity and cellular growth. Essential for regulation of the cytoskeleton and cell growth but not for cell proliferation or growth rate. Required specifically for the microtubule-based basal transport of lipid droplets. Plays a partially redundant function downstream of Raf in cell fate specification in the developing eye. Pair-rule protein that regulates embryonic cellularization, gastrulation and segmentation., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 4, "predicted_n_glycosites": 0, "predicted_o_glycosites": 4, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 9, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 5, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "B7YZZ6;C9QPD1;Q95RP2;Q9BH66", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0003712 transcription coregulator activity;GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding", "go_cellular_component": "GO:0005634 nucleus;GO:0008023 transcription elongation factor complex;GO:0000791 euchromatin;GO:0032783 super elongation complex", "go_biological_process": "GO:0032368 regulation of lipid transport;GO:0034243 regulation of transcription elongation by RNA polymerase II;GO:0007611 learning or memory;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0006355 regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 2.3, "record_id": "Q9VQI9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VQU9-1", "uniprot_id": "BOWEL_DROME", "mass": 79831.0, "length": 744, "protein_name": "Protein bowel", "gene_name": "bowl", "organism": "Fruit fly", "refseq_name": "brother of odd with entrails limited, isoform F", "refseq_ac": "NP_001245861", "gene_names_uniprotkb": "bowl; 17-29-5; BOWL; Bowl; CG10021; Dmel\\CG10021; Dmel_CG10021; Su(tor)2-1; l(2)c; org2", "gene_names_refseq": "17-29-5; BOWL; Bowl; CG10021; Dmel\\CG10021; Su(tor)2-1; bowl; l(2)c; org2", "protein_names_uniprotkb": "Protein bowel; Brother of odd with entrails limited", "protein_names_refseq": "CG10021-PF; bowel; bowl-PF; brother of odd with entrails limited, isoform F; odd skipped-related 2", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG10021)", "pathway_count": 1, "publication_count": 18, "publication_id_list": "10731132;11784087;12537568;12537572;12537573;12537574;14568103;14573519;14597202;16110336;17569856;17569867;18327897;25589440;26109356;26109357;8670819;8878683", "class_list": "", "function": "Putative transcription factor. Required for leg joint formation, acting downstream of Notch to pattern the leg tarsal segments. Functions in the terminal pathway during embryogenesis, acting downstream of tll in the posterior of the embryo. Acts in a hierarchy downstream of drm and lin during foregut and hindgut patterning and morphogenesis. Involved in cell rearrangement during elongation of the embryonic hindgut. Regulates expression of hindgut patterning genes to establish the small intestine region of the embryonic hindgut. Required in the foregut for spatially localized gene expression and morphogenesis of the proventriculus., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 6, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q24219", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0048619 embryonic hindgut morphogenesis;GO:0007442 hindgut morphogenesis;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 1.9, "record_id": "Q9VQU9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VCY8-1", "uniprot_id": "ADRL_DROME", "mass": 49757.0, "length": 444, "protein_name": "Adiponectin receptor protein", "gene_name": "AdipoR", "organism": "Fruit fly", "refseq_name": "adiponectin receptor, isoform D", "refseq_ac": "NP_001247239", "gene_names_uniprotkb": "AdipoR; CG5315; Dmel\\CG5315; Dmel_CG5315; dAdipoR", "gene_names_refseq": "AdipoR; CG5315; Dmel\\CG5315; dAdipoR", "protein_names_uniprotkb": "Adiponectin receptor protein", "protein_names_refseq": "AdipoR-PD; CG5315-PD; adiponectin receptor, isoform D; adiponectin receptor", "tax_id": 7227, "disease": "metabolic dysfunction and alcohol associated liver disease (Disease Ontology:DOID:0070508); alcohol-associated liver disease (Disease Ontology:DOID:0070658); metabolic dysfunction-associated steatotic liver disease (Disease Ontology:DOID:0080208); metabolic dysfunction-associated steatohepatitis (Disease Ontology:DOID:0080547); glucose intolerance (Disease Ontology:DOID:10603); breast cancer (Disease Ontology:DOID:1612); hyperinsulinism (Disease Ontology:DOID:2018); prostate adenocarcinoma (Disease Ontology:DOID:2526); hyperglycemia (Disease Ontology:DOID:4195); macular degeneration (Disease Ontology:DOID:4448); end stage renal disease (Disease Ontology:DOID:783); type 2 diabetes mellitus (Disease Ontology:DOID:9352); steatotic liver disease (Disease Ontology:DOID:9452); obesity (Disease Ontology:DOID:9970)", "pathway": " (dme:Dmel_CG5315)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;23874700;25589440;26109356;26109357", "class_list": "", "function": "Adiponectin receptor. In insulin-producing cells, regulates insulin secretion and controls glucose and lipid metabolism., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 14, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9VCY9", "ec_number_list": "", "go_molecular_function": "GO:0016500 protein-hormone receptor activity;GO:0046872 metal ion binding;GO:0038023 signaling receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane", "go_biological_process": "GO:0032024 positive regulation of insulin secretion;GO:0019395 fatty acid oxidation;GO:0042593 glucose homeostasis;GO:0009755 hormone-mediated signaling pathway;GO:0033211 adiponectin-activated signaling pathway", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "Q9VCY8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VXT7-1", "uniprot_id": "ASGL1_DROME", "mass": 34861.0, "length": 332, "protein_name": "Probable isoaspartyl peptidase/L-asparaginase CG7860", "gene_name": "Dmel\\CG7860", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform B", "refseq_ac": "NP_001285275", "gene_names_uniprotkb": "Dmel\\CG7860; CG7860; Dmel_CG7860", "gene_names_refseq": "CG7860; Dmel\\CG7860", "protein_names_uniprotkb": "Probable isoaspartyl peptidase/L-asparaginase CG7860; 3.4.19.5; 3.5.1.1; Beta-aspartyl-peptidase CG7860; Isoaspartyl dipeptidase CG7860; L-asparagine amidohydrolase CG7860", "protein_names_refseq": "CG7860-PB; uncharacterized protein, isoform B", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG7860); (R-DME-8964208)", "pathway_count": 2, "publication_count": 12, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "Has both L-asparaginase and beta-aspartyl peptidase activity. Does not have aspartylglucosaminidase activity and is inactive toward GlcNAc-L-Asn. Likewise, has no activity toward glutamine., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.4.19.5;3.5.1.1", "go_molecular_function": "GO:0004067 asparaginase activity;GO:0008798 beta-aspartyl-peptidase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0006508 proteolysis;GO:0033345 L-asparagine catabolic process via L-aspartate", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "Q9VXT7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9V895-1", "uniprot_id": "AN32A_DROME", "mass": 29176.0, "length": 261, "protein_name": "Acidic leucine-rich nuclear phosphoprotein 32 family member A", "gene_name": "Anp32a; Mapmodulin", "organism": "Fruit fly", "refseq_name": "mapmodulin, isoform C", "refseq_ac": "NP_001097361", "gene_names_uniprotkb": "Anp32a; Mapmodulin; CG5784; CT18148; CT42180; Dmel\\CG5784; Dmel_CG5784; Mapmodulin; anon-EST:fe3A2", "gene_names_refseq": "CG5784; CT18148; CT42180; Dmel\\CG5784; Mapmodulin; anon-EST:fe3A2", "protein_names_uniprotkb": "Acidic leucine-rich nuclear phosphoprotein 32 family member A", "protein_names_refseq": "CG5784-PC; Mapmodulin-PC; anon-fast-evolving-3A2; mapmodulin, isoform C", "tax_id": 7227, "disease": "candidiasis (Disease Ontology:DOID:1508)", "pathway": " (dme:Dmel_CG5784); (R-DME-450520)", "pathway_count": 2, "publication_count": 14, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;15895553;16110336;17569856;17569867;25589440;26109356;26109357;40245499", "class_list": "", "function": "Implicated in a number of cellular processes, including proliferation, differentiation, caspase-dependent and caspase-independent apoptosis, suppression of transformation (tumor suppressor), inhibition of protein phosphatase 2A, regulation of mRNA trafficking and stability, and inhibition of acetyltransferases as part of the INHAT (inhibitor of histone acetyltransferases) complex., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A2VEM0;Q0E936", "ec_number_list": "", "go_molecular_function": "GO:0042393 histone binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005783 endoplasmic reticulum;GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "GO:0006913 nucleocytoplasmic transport", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "Q9V895-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9V464-1", "uniprot_id": "ASF1_DROME", "mass": 24409.0, "length": 218, "protein_name": "Histone chaperone asf1", "gene_name": "asf1", "organism": "Fruit fly", "refseq_name": "anti-silencing factor 1, isoform B", "refseq_ac": "NP_001189131", "gene_names_uniprotkb": "asf1; ASF-1; ASF1; Asf1; CG9383; Dmel\\CG9383; Dmel_CG9383; SF2; dASF1; dAsf1; l(3)76BDq", "gene_names_refseq": "ASF-1; ASF1; Asf1; CG9383; Dmel\\CG9383; asf1; dASF/SF2; dASF1; dAsf1; l(3)76BDq", "protein_names_uniprotkb": "Histone chaperone asf1; Anti-silencing function protein 1; RCAF subunit ASF1; Replication-coupling assembly factor subunit ASF1; dASF1", "protein_names_refseq": "CG9383-PB; anti- silencing function 1; anti-silencing factor 1, isoform B; anti-silencing factor; asf1-PB", "tax_id": 7227, "disease": "breast cancer (Disease Ontology:DOID:1612)", "pathway": " (dme:Dmel_CG9383)", "pathway_count": 1, "publication_count": 22, "publication_id_list": "10591219;10731132;11533245;12381660;12537568;12537569;12537572;12537573;12537574;14561777;16110336;16151251;16396992;16951084;17569856;17569867;18327897;20016786;25589440;26109356;26109357;28320872", "class_list": "", "function": "Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly (PubMed:10591219, PubMed:12381660, PubMed:14561777, PubMed:16151251, PubMed:16396992). Cooperates with chromatin assembly factor 1 (CAF-1) to promote replication-dependent chromatin assembly (PubMed:11533245). Plays a role in the formation of silent heterochromatin (PubMed:12381660, PubMed:28320872)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0042393 histone binding;GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding", "go_cellular_component": "GO:0005634 nucleus;GO:0017053 transcription repressor complex;GO:0000785 chromatin;GO:0035059 RCAF complex;GO:0005700 polytene chromosome", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0006325 chromatin organization;GO:0006335 DNA replication-dependent chromatin assembly;GO:0048024 regulation of mRNA splicing, via spliceosome", "synthesized_glycan_count": 0, "hit_score": 2.3, "record_id": "Q9V464-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VIS1-1", "uniprot_id": "CDGAP_DROME", "mass": 204217.0, "length": 1843, "protein_name": "GTPase-activating protein CdGAPr", "gene_name": "CdGAPr", "organism": "Fruit fly", "refseq_name": "Cd GTPase activating protein-related, isoform D", "refseq_ac": "NP_001260600", "gene_names_uniprotkb": "CdGAPr; 10538; CG10538; Dmel\\CG10538; Dmel_CG10538; FBgn 32821; GAP; cdGAPr; d-CdGAPr", "gene_names_refseq": "10538; CG10538; CdGAPr; Dmel\\CG10538; FBgn 32821; GAP; cdGAPr; d-CdGAPr", "protein_names_uniprotkb": "GTPase-activating protein CdGAPr; d-CdGAPr", "protein_names_refseq": "CG10538-PD; Cd GTPase activating protein-related, isoform D; CdGAPr-PD", "tax_id": 7227, "disease": "autism spectrum disorder (Disease Ontology:DOID:0060041)", "pathway": " (dme:Dmel_CG10538); (R-DME-8980692); (R-DME-9013148); (R-DME-9013149); (R-DME-9013406); (R-DME-9013409); (R-DME-9013420); (R-DME-9013423); (R-DME-9035034)", "pathway_count": 9, "publication_count": 16, "publication_id_list": "10731132;10842085;12537568;12537569;12537572;12537573;12537574;16110336;17360775;17372656;17569856;17569867;18327897;25589440;26109356;26109357", "class_list": "", "function": "Probably functions as a GTPase-activating protein (GAP) for RAC1 and/or CDC42. Required for optic stalk formation., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 20, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q6AWI4;Q8MSV9;Q9NCL1", "ec_number_list": "", "go_molecular_function": "GO:0005096 GTPase activator activity", "go_cellular_component": "", "go_biological_process": "GO:0007264 small GTPase-mediated signal transduction;GO:0031290 retinal ganglion cell axon guidance;GO:0007165 signal transduction", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "Q9VIS1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VR07-1", "uniprot_id": "INE_DROME", "mass": 103636.0, "length": 943, "protein_name": "Sodium- and chloride-dependent GABA transporter ine", "gene_name": "ine", "organism": "Fruit fly", "refseq_name": "inebriated, isoform F", "refseq_ac": "NP_001162871", "gene_names_uniprotkb": "ine; CG15444d; CG15444; DMINE; Dmel\\CG15444; Dmel_CG15444; rosA", "gene_names_refseq": "CG15444d; CG15444; DMINE; Dmel\\CG15444; ine/rosA; ine; rosA", "protein_names_uniprotkb": "Sodium- and chloride-dependent GABA transporter ine; Protein inebriated; Protein receptor oscillation A", "protein_names_refseq": "CG15444-PF; ine-PF; inebriated, isoform F", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG15444)", "pathway_count": 1, "publication_count": 20, "publication_id_list": "10731132;10876650;11517334;11861562;11880499;12537568;12537569;12537572;12537573;12537574;1334137;16110336;17569856;17569867;17893096;25589440;26109356;26109357;33925313;8917579", "class_list": "", "function": "Plays a role in neuronal membrane excitation, important for normal response properties of the photoreceptor. Able to control excitability from either neurons or glia cells. Ine negatively regulates neuronal sodium channels. Controls neurotransmitter-mediated signaling pathways associated with the structure of the larval peripheral nerve, ine and eag control perineurial glial growth through partially redundant pathways. Isoform A and isoform B are both functional, although isoform A functions with greater efficiency. Has a role in osmolyte transport within the Malpighian tubule and hindgut., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 1, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 1, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 1, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "A4V056;O02003;Q94917", "ec_number_list": "", "go_molecular_function": "GO:0005328 neurotransmitter:sodium symporter activity;GO:0005283 amino acid:sodium symporter activity;GO:0005034 osmosensor activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane;GO:0016323 basolateral plasma membrane", "go_biological_process": "GO:0019226 transmission of nerve impulse;GO:0009414 response to water deprivation;GO:0035725 sodium ion transmembrane transport;GO:0050891 multicellular organismal-level water homeostasis;GO:0006836 neurotransmitter transport", "synthesized_glycan_count": 0, "hit_score": 2.4, "record_id": "Q9VR07-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9W594-1", "uniprot_id": "GR02A_DROME", "mass": 48492.0, "length": 428, "protein_name": "Putative gustatory receptor 2a", "gene_name": "Gr2a", "organism": "Fruit fly", "refseq_name": "gustatory receptor 2a, isoform C", "refseq_ac": "NP_001162633", "gene_names_uniprotkb": "Gr2a; CG18531; Dmel\\CG18531; Dmel_CG18531; EG:BACN32G11.1; GR1F.1; GR2B1; GR2a; Gr1F1; Gr2B1", "gene_names_refseq": "CG18531; Dmel\\CG18531; EG:BACN32G11.1; GR1F.1; GR2B1; GR2a; Gr1F1; Gr2B1; Gr2a", "protein_names_uniprotkb": "Putative gustatory receptor 2a", "protein_names_refseq": "CG18531-PC; Gr2a-PC; gustatory receptor 1F.1; gustatory receptor 2B1; gustatory receptor 2a, isoform C", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG18531)", "pathway_count": 1, "publication_count": 14, "publication_id_list": "10731132;10731137;11516643;12537568;12537572;12537573;12537574;16110336;17569856;17569867;22031876;25589440;26109356;26109357", "class_list": "", "function": "Gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates., [UniProtKB, UniProtKB]; Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its not yet determined substrates., [UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0015276 ligand-gated monoatomic ion channel activity;GO:0008527 taste receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane;GO:0030424 axon;GO:0030425 dendrite;GO:0043025 neuronal cell body", "go_biological_process": "GO:0008049 male courtship behavior;GO:0034220 monoatomic ion transmembrane transport;GO:0007635 chemosensory behavior;GO:0050909 sensory perception of taste;GO:0050912 detection of chemical stimulus involved in sensory perception of taste", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "Q9W594-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9W4M7-1", "uniprot_id": "Q9W4M7_DROME", "mass": 199631.0, "length": 1911, "protein_name": "Twenty-four, isoform B; Twenty-four, isoform C; Twenty-four, isoform I; Twenty-four, isoform J; Twenty-four, isoform N", "gene_name": "tyf", "organism": "Fruit fly", "refseq_name": "twenty-four, isoform C", "refseq_ac": "NP_001162657", "gene_names_uniprotkb": "tyf; CG4857; CG485; Dmel\\CG4857; Dmel_CG4857; EG:EG0007.12; EG:EG0007.4; TYF", "gene_names_refseq": "CG4857; CG485; Dmel\\CG4857; EG:EG0007.12; EG:EG0007.4; TYF; tyf", "protein_names_uniprotkb": "Twenty-four, isoform B; Twenty-four, isoform C; Twenty-four, isoform I; Twenty-four, isoform J; Twenty-four, isoform N", "protein_names_refseq": "CG4857-PC; TWENTY-FOUR; twenty four; twenty-four, isoform C; tyf-PC", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG4857)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357;33925313;40245499", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 5, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 5, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 5, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 6, "binding_glycan_count": 0, "secondary_ac_list": "E1JJD4;O97423;O97424", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "GO:0042742 defense response to bacterium;GO:0045727 positive regulation of translation;GO:0045475 locomotor rhythm", "synthesized_glycan_count": 0, "hit_score": 2.0, "record_id": "Q9W4M7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VYD1-1", "uniprot_id": "SET2_DROME", "mass": 256791.0, "length": 2313, "protein_name": "Histone-lysine N-methyltransferase Set2", "gene_name": "Set2", "organism": "Fruit fly", "refseq_name": "SET domain containing 2, isoform B", "refseq_ac": "NP_001162740", "gene_names_uniprotkb": "Set2; CG1716; Dmel\\CG1716; Dmel_CG1716; Hypb; SET-2; SET2; dHypb; dSet2; set2", "gene_names_refseq": "CG1716; Dmel\\CG1716; Hypb; SET-2; SET2; Set2; dHypb; dSet2; set2", "protein_names_uniprotkb": "Histone-lysine N-methyltransferase Set2; 2.1.1.359; dSet2", "protein_names_refseq": "CG1716-PB; SET domain containing 2, isoform B; Set2-PB; drosophila hypb", "tax_id": 7227, "disease": "idiopathic pulmonary fibrosis (Disease Ontology:DOID:0050156); autosomal dominant intellectual developmental disorder 70 (Disease Ontology:DOID:0061043); stomach cancer (Disease Ontology:DOID:10534); cancer (Disease Ontology:DOID:162); malignant mesothelioma (Disease Ontology:DOID:1790); liver cancer (Disease Ontology:DOID:3571); lung adenocarcinoma (Disease Ontology:DOID:3910); clear cell renal cell carcinoma (Disease Ontology:DOID:4467); malignant pleural mesothelioma (Disease Ontology:DOID:7474); gastrointestinal stromal tumor (Disease Ontology:DOID:9253); colorectal cancer (Disease Ontology:DOID:9256)", "pathway": " (dme:Dmel_CG1716)", "pathway_count": 1, "publication_count": 16, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17560546;17569856;17569867;17936709;18327897;25589440;26109356;26109357;34878097", "class_list": "", "function": "Histone methyltransferase that specifically trimethylates 'Lys-36' of histone H3 (H3K36me3) (PubMed:17560546, PubMed:17936709). Represents the main enzyme generating H3K36me3, a specific tag for epigenetic transcriptional activation (PubMed:17560546). Involved in dosage compensation in males (X chromosome dosage compensation) by mediating formation of H3K36me3, a mark recognized by msl-3 component of the MSL complex (PubMed:17936709). In addition to its role in dosage compensation in males, promotes germline stem cell differentiation in females: catalyzes formation of H3K36me3, promoting recruitment of msl-3 and subsequent recruitment of the ATAC complex, leading to transcription of genes, such as RpS19b (PubMed:34878097)., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 11, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "Q1RL18;Q961S6;Q9VYD0", "ec_number_list": "2.1.1.359;2.1.1.372", "go_molecular_function": "GO:0003677 DNA binding;GO:0046872 metal ion binding;GO:0051219 phosphoprotein binding;GO:0046975 histone H3K36 methyltransferase activity;GO:0140955 histone H3K36 trimethyltransferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0000785 chromatin;GO:0005694 chromosome", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006355 regulation of DNA-templated transcription;GO:0006325 chromatin organization;GO:0007281 germ cell development;GO:0032259 methylation", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "Q9VYD1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9XYP7-1", "uniprot_id": "GCP2_DROME", "mass": 98505.0, "length": 852, "protein_name": "Gamma-tubulin complex component 2 homolog", "gene_name": "Grip84", "organism": "Fruit fly", "refseq_name": "Gamma-tubulin ring protein 84, isoform F", "refseq_ac": "NP_001285444", "gene_names_uniprotkb": "Grip84; CG3917; DGrip84; Dgrip84; Dgrips84; Dmel\\CG3917; Dmel_CG3917; GCP2; grip84; l(1)[[t]]PG36; l(1)[[t]]PG66", "gene_names_refseq": "CG3917; DGrip84; Dgrip84; Dgrips84; Dmel\\CG3917; GCP2; Grip84; grip84; l(1)[[t]]PG36; l(1)[[t]]PG66", "protein_names_uniprotkb": "Gamma-tubulin complex component 2 homolog; Gamma-ring complex protein 84 kDa; d84p; dGrip84", "protein_names_refseq": "CG3917-PF; DGrip84; Gamma-tubulin ring protein 84, isoform F; Grip84-PF; gamma-tubulin ring protein 84", "tax_id": 7227, "disease": "complex cortical dysplasia with other brain malformations 15 (Disease Ontology:DOID:0081266)", "pathway": " (dme:Dmel_CG3917)", "pathway_count": 1, "publication_count": 17, "publication_id_list": "10037793;10731132;12537568;12537569;12537572;12537573;12537574;16110336;17372656;17569856;17569867;25589440;26109356;26109357;32066907;33925313;40245499", "class_list": "", "function": "Component of the gamma-tubulin ring complex (gTuRC) which mediates microtubule nucleation. The gTuRC regulates the minus-end nucleation of alpha-beta tubulin heterodimers that grow into microtubule protafilaments, a critical step in centrosome duplication and spindle formation. Plays a role in neuronal migration., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 2, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 2, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 2, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 1, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "Q95RT7", "ec_number_list": "", "go_molecular_function": "GO:0043015 gamma-tubulin binding", "go_cellular_component": "GO:0008275 gamma-tubulin small complex;GO:0000922 spindle pole;GO:0005813 centrosome;GO:0005874 microtubule;GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "GO:0000278 mitotic cell cycle;GO:0007283 spermatogenesis;GO:0007020 microtubule nucleation;GO:0007098 centrosome cycle;GO:0051225 spindle assembly", "synthesized_glycan_count": 0, "hit_score": 2.1, "record_id": "Q9XYP7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VT28-1", "uniprot_id": "FRY_DROME", "mass": 384352.0, "length": 3479, "protein_name": "Protein furry", "gene_name": "fry", "organism": "Fruit fly", "refseq_name": "furry, isoform B", "refseq_ac": "NP_729520", "gene_names_uniprotkb": "fry; CG14171; CG32045; CG6774; CG6780; Dmel\\CG32045; Dmel_CG32045; Fry; RE-B; SS3-7; l(3)02240; yeti", "gene_names_refseq": "CG14171; CG32045; CG6774; CG6780; Dmel\\CG32045; Fry; RE-B; SS3-7; fry; l(3)02240; yeti", "protein_names_uniprotkb": "Protein furry", "protein_names_refseq": "CG32045-PB; fry-PB; furry, isoform B; furry; suppressor of GMR-sina 3-7", "tax_id": 7227, "disease": "syndromic intellectual disability (Disease Ontology:DOID:0050888); Pan-Chung-Bellen syndrome (Disease Ontology:DOID:0061146)", "pathway": " (dme:Dmel_CG32045)", "pathway_count": 1, "publication_count": 16, "publication_id_list": "10731132;11526084;12537568;12537569;12537572;12537573;12537574;15479641;16110336;17569856;17569867;18327897;25589440;26109356;26109357;32022690", "class_list": "", "function": "Plays a role in the Trc/fry signaling pathway by promoting trc kinase activity (PubMed:11526084, PubMed:15479641, PubMed:32022690). Plays a key role in maintaining the integrity of polarized cell extensions (arista) during morphogenesis, regulates the actin cytoskeleton (PubMed:11526084). Plays a key role in patterning sensory neuron dendritic fields by promoting avoidance between homologous dendrites as well as by limiting dendritic branching (PubMed:15479641). Together with trc, has a role in regulating microtubule-sliding during neurite outgrowth (PubMed:32022690)., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 15, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "Q0E8G4;Q8T9A1;Q9BIR5;Q9GPT8", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005938 cell cortex;GO:0030424 axon;GO:0030425 dendrite;GO:0045177 apical part of cell", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0031175 neuron projection development;GO:0048814 regulation of dendrite morphogenesis;GO:0045860 positive regulation of protein kinase activity;GO:0000902 cell morphogenesis", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "Q9VT28-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9XYM0-1", "uniprot_id": "CRK_DROME", "mass": 31205.0, "length": 271, "protein_name": "Adapter molecule Crk", "gene_name": "Crk", "organism": "Fruit fly", "refseq_name": "Crk oncogene, isoform A", "refseq_ac": "NP_651908", "gene_names_uniprotkb": "Crk; CED-2; CG1587; CRK; D-CRK; D-Crk; DCrk; Dcrk; Dmel\\CG1587; Dmel_CG1587; crk; dCRK; dCrk", "gene_names_refseq": "CED-2; CG1587; CRK; Crk; D-CRK; D-Crk; DCrk; Dcrk; Dmel\\CG1587; crk; dCRK; dCrk", "protein_names_uniprotkb": "Adapter molecule Crk", "protein_names_refseq": "CG1587-PA; Crk oncogene, isoform A; Crk-PA", "tax_id": 7227, "disease": "prostate carcinoma (Disease Ontology:DOID:10286); DiGeorge syndrome (Disease Ontology:DOID:11198); velocardiofacial syndrome (Disease Ontology:DOID:12583); colon carcinoma (Disease Ontology:DOID:1520); ovarian cancer (Disease Ontology:DOID:2394); invasive ductal carcinoma (Disease Ontology:DOID:3008); lung carcinoma (Disease Ontology:DOID:3905); skin cancer (Disease Ontology:DOID:4159); chronic myeloid leukemia (Disease Ontology:DOID:8552); degenerative disc disease (Disease Ontology:DOID:90)", "pathway": " (dme:Dmel_CG1587); (R-DME-186763); (R-DME-8849471); (R-DME-912631)", "pathway_count": 4, "publication_count": 12, "publication_id_list": "10072777;10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "Adapter protein which interacts with C-terminal portion of mbc, homolog of human DOCK180. May play a role in cellular processes throughout development., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 10, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q53XD2", "ec_number_list": "", "go_molecular_function": "GO:0030971 receptor tyrosine kinase binding;GO:0035591 signaling adaptor activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0006911 phagocytosis, engulfment;GO:0016477 cell migration;GO:0032956 regulation of actin cytoskeleton organization;GO:0046330 positive regulation of JNK cascade;GO:0048013 ephrin receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "Q9XYM0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9V496-1", "uniprot_id": "APLP_DROME", "mass": 372677.0, "length": 3351, "protein_name": "Apolipophorins", "gene_name": "apolpp", "organism": "Fruit fly", "refseq_name": "apolipophorin, isoform B", "refseq_ac": "NP_001259085", "gene_names_uniprotkb": "apolpp; ApoL1; ApoL2; ApoLII; ApoLI; ApoLpp; Apolpp; CG11064; DRBP; Dmel\\CG11064; Dmel_CG11064; LPP; Lipophorin; Lpp; RFABG; RFABP; RFBP; RfaBP; RfaBp; Rfabg; Rfabp; T3; apoLII; apoLI; apoLPP; apoLpp; chr4:1088013..1088173; lipophorin; rfabg", "gene_names_refseq": "ApoL1; ApoL2; ApoLII; ApoLI; ApoLpp; Apolpp; CG11064; DRBP; Dmel\\CG11064; LPP; Lipophorin; Lpp; RFABG; RFABP; RFBP; RfaBP; RfaBp; Rfabg; Rfabp; T3; apoLII; apoLI; apoLPP; apoLpp; apolpp; chr4:1088013..1088173; lipophorin; rfabg", "protein_names_uniprotkb": "Apolipophorins; ApoL1; ApoL2; ApoLII; ApoLI; Apolipophorin II; Apolipophorin I; Retinoid- and fatty acid-binding glycoprotein", "protein_names_refseq": "CG11064-PB; Retinoid- and fatty acid-binding glycoprotein; Retinoid- and fatty acid-binding protein; Retinoid- and fatty-acid binding protein; Retinoid-fatty acid-binding glycoprotein; RfaBp; apolipophorin II; apolipophorin, isoform B; apolipophorin-2; apolpp-PB; lipophorin; retinoid and fatty acid binding glycoprotein; retinoid and fatty acid binding protein; retinoid and fatty-acid binding protein; retinoid- and fatty acid-binding gene; retinoid-fatty acid binding protein", "tax_id": 7227, "disease": "congenital heart disease (Disease Ontology:DOID:1682)", "pathway": " (dme:Dmel_CG11064)", "pathway_count": 1, "publication_count": 20, "publication_id_list": "10393207;10731132;11778050;12537568;12537572;12537573;12537574;15062105;15875013;16110336;17569856;17569867;17893096;23352167;25589440;26109356;26109357;33891588;8031123;8702812", "class_list": "", "function": "Constitutes the major component of lipophorin, which mediates transport for various types of lipids in hemolymph. Acts by forming lipoprotein particles that bind lipoproteins and lipids. Also involved in the transport of hydrophobic ligands like juvenile hormones, pheromone hydrocarbons and carotenoids. Required for morphogens wingless (wg) and hedgehog (hh) function, probably by acting as vehicles for the movement of wg and hh, explaining how covalently lipidated wg and hh can spread over long distances. May also be involved in transport and/or metabolism of heme. Involved in yolk granule formation (PubMed:33891588). May be a component of yolk incorporated into yolk granules via yl/yolkless-mediated endocytosis and the endolysosomal pathway (PubMed:33891588)., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 7, "predicted_n_glycosites": 6, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 1, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 1, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 1, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 8, "binding_glycan_count": 0, "secondary_ac_list": "Q8ST55;Q8T6S6;Q94907", "ec_number_list": "", "go_molecular_function": "GO:0005102 signaling receptor binding;GO:0005319 lipid transporter activity;GO:0005504 fatty acid binding;GO:0008017 microtubule binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0005615 extracellular space;GO:0045178 basal part of cell;GO:0030139 endocytic vesicle;GO:0016028 rhabdomere", "go_biological_process": "GO:0045880 positive regulation of smoothened signaling pathway;GO:0006869 lipid transport;GO:0042953 lipoprotein transport;GO:0016055 Wnt signaling pathway;GO:0090263 positive regulation of canonical Wnt signaling pathway", "synthesized_glycan_count": 0, "hit_score": 2.2, "record_id": "Q9V496-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9V498-1", "uniprot_id": "CSTN1_DROME", "mass": 110493.0, "length": 978, "protein_name": "Calsyntenin-1", "gene_name": "Cals", "organism": "Fruit fly", "refseq_name": "calsyntenin, isoform D", "refseq_ac": "NP_001284722", "gene_names_uniprotkb": "Cals; Alcalpha; CALS; CG11059; CLSTN1; CT30877; Cad102F; DCad102F; Dmel\\CG11059; Dmel_CG11059; cals; dAlc", "gene_names_refseq": "Alcalpha; CALS; CG11059; CT30877; Cad102F; Cals; DCad102F; Dmel\\CG11059; cals; dAlc", "protein_names_uniprotkb": "Calsyntenin-1; Cadherin-102F", "protein_names_refseq": "CG11059-PD; Cals-PD; Calsyntenin-1; alcadeinalpha; calsyntenin, isoform D; calsyntenin-1-like", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG11059)", "pathway_count": 1, "publication_count": 14, "publication_id_list": "10731132;11161476;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;17893096;25589440;26109356;26109357", "class_list": "", "function": "Postsynaptic adhesion molecule that binds to presynaptic neurexins to mediate both excitatory and inhibitory synapse formation (By similarity). Promotes synapse development by acting as a cell adhesion molecule at the postsynaptic membrane, which associates with neurexin-alpha at the presynaptic membrane (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 5, "predicted_n_glycosites": 4, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 1, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 1, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 1, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 6, "binding_glycan_count": 0, "secondary_ac_list": "A4V137;Q9GP64", "ec_number_list": "", "go_molecular_function": "GO:0005509 calcium ion binding;GO:0098632 cell-cell adhesion mediator activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0005886 plasma membrane;GO:0009986 cell surface;GO:0045211 postsynaptic membrane;GO:0098839 postsynaptic density membrane", "go_biological_process": "GO:0030154 cell differentiation;GO:0051965 positive regulation of synapse assembly;GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules;GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0044331 cell-cell adhesion mediated by cadherin", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "Q9V498-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VS59-1", "uniprot_id": "AKIRN_DROME", "mass": 22705.0, "length": 201, "protein_name": "Akirin", "gene_name": "akirin", "organism": "Fruit fly", "refseq_name": "akirin, isoform C", "refseq_ac": "NP_001189058", "gene_names_uniprotkb": "akirin; Akirin; CG8580; DmAkirin; Dmel\\CG8580; Dmel_CG8580; EP(3)0906; anon-WO0118547.397; bhr", "gene_names_refseq": "Akirin; CG8580; DmAkirin; Dmel\\CG8580; EP(3)0906; akirin; anon-WO0118547.397; bhr", "protein_names_uniprotkb": "Akirin; Protein bhringi", "protein_names_refseq": "CG8580-PC; akirin, isoform C; akirin-PC; bhringi", "tax_id": 7227, "disease": "opportunistic bacterial infectious disease (Disease Ontology:DOID:0050340)", "pathway": " (dme:Dmel_CG8580)", "pathway_count": 1, "publication_count": 19, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;18066067;18327897;22396663;24947515;25180232;25589440;26109356;26109357;32339205;32950464", "class_list": "", "function": "Molecular adapter that acts as a bridge between a variety of multiprotein complexes, and which is required for embryonic development and for normal innate immune response (PubMed:18066067, PubMed:22396663, PubMed:25180232, PubMed:32950464). Acts as a regulator of embryonic myogenesis by bridging Twist (twi) with the SWI/SNF-like Brahma complex, promoting expression of twi-regulated genes during myogenesis (PubMed:22396663). Effector of immune deficiency pathway (Imd) by acting either downstream of, or at the level of, the NF-kappa-B factor Relish (Rel) (PubMed:18066067, PubMed:25180232, PubMed:32950464). Acts by bridging the NF-kappa-B factor Rel and the Brahma complex through bap60 interaction, leading to activation a subset of NF-kappa-B factor Relish (Rel) effector genes (PubMed:25180232). Not part of the Toll pathway (PubMed:18066067). Required for the formation of the heart by promoting expression ot tinman (tin) (PubMed:32950464)., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003712 transcription coregulator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0000785 chromatin;GO:0000791 euchromatin;GO:0005700 polytene chromosome", "go_biological_process": "GO:0007507 heart development;GO:0045087 innate immune response;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0050829 defense response to Gram-negative bacterium;GO:0045089 positive regulation of innate immune response", "synthesized_glycan_count": 0, "hit_score": 2.0, "record_id": "Q9VS59-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9W352-1", "uniprot_id": "CXXC1_DROME", "mass": 76696.0, "length": 663, "protein_name": "CXXC-type zinc finger protein 1", "gene_name": "Cfp1", "organism": "Fruit fly", "refseq_name": "CXXC finger protein 1, isoform A", "refseq_ac": "NP_572556", "gene_names_uniprotkb": "Cfp1; CG17446; CXXC1; Dmel\\CG17446; Dmel_CG17446; dCXXC1; dCfp1", "gene_names_refseq": "CG17446; CXXC1; Cfp1; Dmel\\CG17446; dCXXC1; dCfp1", "protein_names_uniprotkb": "CXXC-type zinc finger protein 1; PHD finger and CXXC domain-containing protein 1", "protein_names_refseq": "CG17446-PA; CXXC finger protein 1, isoform A; Cfp1-PA", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG17446); (R-DME-9772755)", "pathway_count": 2, "publication_count": 14, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17372656;17569856;17569867;21694722;21875999;25589440;26109356;26109357", "class_list": "", "function": "Component of the SET1 complex that specifically di- and trimethylates 'Lys-4' of histone H3. Essential for Set1 association with chromatin and trimethylation of histone H3 at 'Lys-4' at transcription puffs. Additionally, is critical for general chromosomal association of Set1., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005634 nucleus;GO:0048188 Set1C/COMPASS complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045893 positive regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "Q9W352-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VY77-1", "uniprot_id": "AJUBA_DROME", "mass": 77961.0, "length": 728, "protein_name": "LIM domain-containing protein jub", "gene_name": "jub", "organism": "Fruit fly", "refseq_name": "ajuba LIM protein, isoform B", "refseq_ac": "NP_572930", "gene_names_uniprotkb": "jub; Ajuba; CG11063; Djub; Dmel\\CG11063; Dmel_CG11063; JUB; Jub; dJub; djub", "gene_names_refseq": "Ajuba; CG11063; Djub; Dmel\\CG11063; JUB; Jub; dJub; djub; jub", "protein_names_uniprotkb": "LIM domain-containing protein jub", "protein_names_refseq": "CG11063-PB; ajuba LIM protein, isoform B; ajuba LIM; djub; drosophila ajuba LIM protein; jub-PB", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG11063); (R-DME-1234176); (R-DME-9841922)", "pathway_count": 3, "publication_count": 13, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;20303269;25589440;26109356;26109357", "class_list": "", "function": "Regulates organ size by inhibiting apoptosis and promoting cell proliferation by influencing the expression of G1/S-specific cyclin-E (CycE) and apoptosis 1 inhibitor (th). Negatively regulates the Hippo signaling pathway., [UniProtKB, PubMed]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "Q8SZR9", "ec_number_list": "", "go_molecular_function": "GO:0046872 metal ion binding;GO:0003714 transcription corepressor activity;GO:0140311 protein sequestering activity", "go_cellular_component": "GO:0045179 apical cortex;GO:0005634 nucleus;GO:0005912 adherens junction;GO:0000932 P-body;GO:0005667 transcription regulator complex", "go_biological_process": "GO:0000278 mitotic cell cycle;GO:0001666 response to hypoxia;GO:0006355 regulation of DNA-templated transcription;GO:0007010 cytoskeleton organization;GO:0035331 negative regulation of hippo signaling", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "Q9VY77-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VJD3-1", "uniprot_id": "COG5_DROME", "mass": 84954.0, "length": 751, "protein_name": "Conserved oligomeric Golgi complex subunit 5", "gene_name": "fws", "organism": "Fruit fly", "refseq_name": "four way stop, isoform D", "refseq_ac": "NP_001246059", "gene_names_uniprotkb": "fws; CG6549; COG5; Cog5; Dmel\\CG6549; Dmel_CG6549; FWS; Fws; anon-EST:Posey162; anon-EST:Posey186; dCOG5", "gene_names_refseq": "CG6549; COG5; Cog5; Dmel\\CG6549; FWS; Fws; anon-EST:Posey162; anon-EST:Posey186; dCOG5; fws", "protein_names_uniprotkb": "Conserved oligomeric Golgi complex subunit 5; COG complex subunit 5; Component of oligomeric Golgi complex 5; Protein four way stop", "protein_names_refseq": "CG6549-PD; Four-way stop; drosophila Cog5; four Way stop; four way stop, isoform D; fws-PD", "tax_id": 7227, "disease": "congenital disorder of glycosylation type IIi (Disease Ontology:DOID:0070261)", "pathway": " (dme:Dmel_CG6549); (R-DME-6807878); (R-DME-6811438); (R-DME-6811440)", "pathway_count": 4, "publication_count": 13, "publication_id_list": "10731132;12529436;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "Required for normal Golgi function and necessary during spermatogenesis. Required for cleavage furrow ingression during cytokinesis in dividing spermatocytes and for the extensive polarized cell growth that accompanies spermatid elongation., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q53YG5;Q8T0G3", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005794 Golgi apparatus;GO:0070971 endoplasmic reticulum exit site;GO:0017119 Golgi transport complex", "go_biological_process": "GO:0015031 protein transport;GO:0001675 acrosome assembly;GO:0007030 Golgi organization;GO:0000301 retrograde transport, vesicle recycling within Golgi;GO:0000916 actomyosin contractile ring contraction", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "Q9VJD3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9W0P5-1", "uniprot_id": "GALE_DROME", "mass": 38697.0, "length": 350, "protein_name": "UDP-glucose 4-epimerase", "gene_name": "Gale", "organism": "Fruit fly", "refseq_name": "UDP-galactose 4'-epimerase, isoform B", "refseq_ac": "NP_001246537", "gene_names_uniprotkb": "Gale; CG12030; Dmel\\CG12030; Dmel_CG12030; GALE; dGALE", "gene_names_refseq": "CG12030; Dmel\\CG12030; GALE; Gale; dGALE", "protein_names_uniprotkb": "UDP-glucose 4-epimerase; 5.1.3.2; 5.1.3.7; Galactowaldenase; UDP-GalNAc 4-epimerase; UDP-GlcNAc 4-epimerase; UDP-N-acetylgalactosamine 4-epimerase; UDP-N-acetylglucosamine 4-epimerase; UDP-galactose 4-epimerase", "protein_names_refseq": "CG12030-PB; Gale-PB; UDP-gal 4' epimerase; UDP-galactose 4'-epimerase, isoform B", "tax_id": 7227, "disease": "galactose epimerase deficiency (Disease Ontology:DOID:0111458); thrombocytopenia (Disease Ontology:DOID:1588); galactosemia (Disease Ontology:DOID:9870)", "pathway": " (dme:Dmel_CG12030); (R-DME-70370)", "pathway_count": 2, "publication_count": 14, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;20519568;22654673;25589440;26109356;26109357", "class_list": "", "function": "Catalyzes two distinct but analogous reactions: the reversible epimerization of UDP-glucose to UDP-galactose and the reversible epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine (PubMed:20519568, PubMed:22654673). The reaction with UDP-Gal plays a critical role in the Leloir pathway of galactose catabolism in which galactose is converted to the glycolytic intermediate glucose 6-phosphate. It contributes to the catabolism of dietary galactose and enables the endogenous biosynthesis of both UDP-Gal and UDP-GalNAc when exogenous sources are limited (PubMed:22654673). Both UDP-sugar interconversions are important in the synthesis of glycoproteins and glycolipids., [UniProtKB, PubMed, PubMed, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "5.1.3.2;5.1.3.7", "go_molecular_function": "GO:0003978 UDP-glucose 4-epimerase activity;GO:0003974 UDP-N-acetylglucosamine 4-epimerase activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0006048 UDP-N-acetylglucosamine biosynthetic process;GO:0033499 galactose catabolic process via UDP-galactose, Leloir pathway;GO:0052574 UDP-galactose biosynthetic process;GO:0019277 UDP-N-acetylgalactosamine biosynthetic process;GO:0120530 UDP-alpha-D-glucose biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "Q9W0P5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VW60-1", "uniprot_id": "ADCY2_DROME", "mass": 142817.0, "length": 1307, "protein_name": "Adenylate cyclase type 2", "gene_name": "Ac76E", "organism": "Fruit fly", "refseq_name": "adenylyl cyclase 76E, isoform A", "refseq_ac": "NP_524173", "gene_names_uniprotkb": "Ac76E; AC 76E; AC76E; CG7978; DAC2; DAC76E; Dmel\\CG7978; Dmel_CG7978; ac76e; dADCY2", "gene_names_refseq": "AC 76E; AC76E; Ac76E; CG7978; DAC2; DAC76E; Dmel\\CG7978; ac76e; dADCY2", "protein_names_uniprotkb": "Adenylate cyclase type 2; 4.6.1.1; ATP pyrophosphate-lyase 2; Adenylyl cyclase 76E", "protein_names_refseq": "Ac76E-PA; AdenylateCyclase E; CG7978-PA; adenylyl cyclase 76E, isoform A; adenylyl cyclase", "tax_id": 7227, "disease": "congenital heart disease (Disease Ontology:DOID:1682); chronic obstructive pulmonary disease (Disease Ontology:DOID:3083); bipolar disorder (Disease Ontology:DOID:3312)", "pathway": " (dme:Dmel_CG7978); (R-DME-163615); (R-DME-170660); (R-DME-170670); (R-DME-418597); (R-DME-5610787)", "pathway_count": 6, "publication_count": 13, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;1739965;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "Catalyzes the formation of the signaling molecule cAMP in response to G protein signaling., [UniProtKB, UniProtKB]", "predicted_glycosites": 5, "predicted_n_glycosites": 4, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "O77247;Q8MRK9", "ec_number_list": "4.6.1.1", "go_molecular_function": "GO:0004016 adenylate cyclase activity;GO:0005524 ATP binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0006171 cAMP biosynthetic process;GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0035556 intracellular signal transduction;GO:0042594 response to starvation;GO:0040015 negative regulation of multicellular organism growth", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "Q9VW60-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VUQ8-1", "uniprot_id": "DCNL1_DROME", "mass": 33695.0, "length": 288, "protein_name": "DCN1-like protein 1", "gene_name": "SCCRO", "organism": "Fruit fly", "refseq_name": "squamous cell carcinoma-related oncogene, isoform E", "refseq_ac": "NP_001261883", "gene_names_uniprotkb": "SCCRO; CG7427; Dcun1d1; Dmel\\CG7427; Dmel_CG7427; Sccro; dSCCRO", "gene_names_refseq": "CG7427; Dmel\\CG7427; SCCRO; Sccro; dSCCRO", "protein_names_uniprotkb": "DCN1-like protein 1; DCNL1; DCUN1 domain-containing protein 1; Defective in cullin neddylation protein 1-like protein 1; Squamous cell carcinoma-related oncogene", "protein_names_refseq": "CG7427-PE; SCCRO-PE; squamous cell carcinoma-related oncogene ortholog; squamous cell carcinoma-related oncogene, isoform E", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG7427); (R-DME-8951664)", "pathway_count": 2, "publication_count": 13, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357;26792857", "class_list": "", "function": "Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Promotes neddylation of cullin components of SCF-type E3 ubiquitin ligase complexes and thus regulates SCF-type complex activity. Function promotes cell proliferation., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0032182 ubiquitin-like protein binding;GO:0097602 cullin family protein binding;GO:0031624 ubiquitin conjugating enzyme binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0000151 ubiquitin ligase complex", "go_biological_process": "GO:0045116 protein neddylation;GO:0035212 cell competition in a multicellular organism;GO:2000436 positive regulation of protein neddylation", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "Q9VUQ8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9W0S9-1", "uniprot_id": "DIP2_DROME", "mass": 194154.0, "length": 1773, "protein_name": "Disco-interacting protein 2", "gene_name": "DIP2", "organism": "Fruit fly", "refseq_name": "DISCO interacting protein 2, isoform A", "refseq_ac": "NP_612019", "gene_names_uniprotkb": "DIP2; CG7020; Ddip2; Dmel\\CG7020; Dmel_CG7020", "gene_names_refseq": "CG7020; DIP2; Ddip2; Dmel\\CG7020", "protein_names_uniprotkb": "Disco-interacting protein 2", "protein_names_refseq": "CG7020-PA; DIP2-PA; DISCO interacting protein 2, isoform A", "tax_id": 7227, "disease": "autosomal dominant intellectual developmental disorder type FRA12A (Disease Ontology:DOID:0061049)", "pathway": " (dme:Dmel_CG7020)", "pathway_count": 1, "publication_count": 16, "publication_id_list": "10731132;12137943;12537568;12537572;12537573;12537574;16110336;17569856;17569867;18327897;25589440;26109356;26109357;27908785;28396149;28465232", "class_list": "", "function": "Required for precise axonal bifurcation in mushroom body neurons by suppressing ectopic bifurcation and regulating the guidance of sister axons (PubMed:27908785, PubMed:28396149). May function by regulating expression of tdp1 (PubMed:28465232). Acts downstream of the serine/threonine-protein kinase Bsk to modulate the direction of axon projection (PubMed:28396149). May play a role in fatty acid metabolism (PubMed:27908785)., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9NGP2", "ec_number_list": "", "go_molecular_function": "GO:0003987 acetate-CoA ligase activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0006085 acetyl-CoA biosynthetic process;GO:0007411 axon guidance", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "Q9W0S9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VVW1-1", "uniprot_id": "A76A_DROME", "mass": 43967.0, "length": 386, "protein_name": "Accessory gland protein Acp76A", "gene_name": "Acp76A", "organism": "Fruit fly", "refseq_name": "accessory gland protein 76A, isoform A", "refseq_ac": "NP_524153", "gene_names_uniprotkb": "Acp76A; (Acp)76A; Acp76; CG3801; Dmel\\CG3801; Dmel_CG3801; Spn76A", "gene_names_refseq": "(Acp)76A; Acp76A; Acp76; CG3801; Dmel\\CG3801; Spn76A", "protein_names_uniprotkb": "Accessory gland protein Acp76A", "protein_names_refseq": "Acp76A-PA; CG3801-PA; accessory gland protein 76A, isoform A; accessory gland-specific peptide 76A", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG3801); (R-DME-114608); (R-DME-194002); (R-DME-2022377); (R-DME-204005); (R-DME-381426); (R-DME-5694530); (R-DME-6798695); (R-DME-8957275); (R-DME-9757110); (R-DME-9769739)", "pathway_count": 11, "publication_count": 13, "publication_id_list": "10731132;11102381;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357;9474779", "class_list": "", "function": "Responsible for physiological and behavioral changes in mated female flies. May play a role in accessory protein regulation and/or in the coagulation of seminal fluid to form a mating plug., [UniProtKB, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "O46224", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0007320 insemination;GO:0007618 mating", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "Q9VVW1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VJD2-1", "uniprot_id": "LTOR3_DROME", "mass": 13781.0, "length": 124, "protein_name": "Ragulator complex protein LAMTOR3 homolog", "gene_name": "Lamtor3", "organism": "Fruit fly", "refseq_name": "late endosomal/lysosomal adaptor, MAPK and MTOR activator 3, isoform B", "refseq_ac": "NP_001246062", "gene_names_uniprotkb": "Lamtor3; BcDNA:RE09173; CG5110; Dmel\\CG5110; Dmel_CG5110; MP1; dMP1", "gene_names_refseq": "BcDNA:RE09173; CG5110; Dmel\\CG5110; Lamtor3; MP1; dMP1", "protein_names_uniprotkb": "Ragulator complex protein LAMTOR3 homolog; Late endosomal/lysosomal adaptor and MAPK and MTOR activator 3", "protein_names_refseq": "CG5110-PB; Lamtor3-PB; late endosomal/lysosomal adaptor, MAPK and MTOR activator 3, isoform B", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG5110); (R-DME-1632852); (R-DME-165159); (R-DME-166208); (R-DME-380972); (R-DME-5628897); (R-DME-5674135); (R-DME-6798695); (R-DME-8943724); (R-DME-9639288)", "pathway_count": 10, "publication_count": 13, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;20381137;25589440;26109356;26109357", "class_list": "", "function": "Regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factors, energy levels, and amino acids. As part of the Ragulator complex, may activate the TOR signaling cascade in response to amino acids., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0071986 Ragulator complex;GO:0005737 cytoplasm", "go_biological_process": "GO:1904263 positive regulation of TORC1 signaling;GO:0032008 positive regulation of TOR signaling;GO:0008104 intracellular protein localization;GO:0038202 TORC1 signaling;GO:0071230 cellular response to amino acid stimulus", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "Q9VJD2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VMJ7-1", "uniprot_id": "KDM5_DROME", "mass": 203993.0, "length": 1838, "protein_name": "Lysine-specific demethylase 5", "gene_name": "Kdm5", "organism": "Fruit fly", "refseq_name": "lysine demethylase 5, isoform C", "refseq_ac": "NP_001245908", "gene_names_uniprotkb": "Kdm5; CG9088; Dmel\\CG9088; Dmel_CG9088; KDM5; LID; Lid; dJARID1; dKDM5; kdm5; l(2)10424; lid", "gene_names_refseq": "CG9088; Dmel\\CG9088; KDM5; Kdm5; LID; Lid/KDM5; Lid; dJARID1; dKDM5/LID; dKDM5; kdm5; l(2)10424; lid", "protein_names_uniprotkb": "Lysine-specific demethylase 5; 1.14.11.67; Histone demethylase lid; Jumonji/ARID domain-containing protein lid; Protein little imaginal disks; Retinoblastoma-binding protein 2 homolog; [histone H3]-trimethyl-L-lysine(4) demethylase Kdm5; lid", "protein_names_refseq": "CG9088-PC; Kdm5-PC; little imaginal discs; little imaginal disks; lysine demethylase 5, isoform C", "tax_id": 7227, "disease": "syndromic intellectual disability (Disease Ontology:DOID:0050888); autism spectrum disorder (Disease Ontology:DOID:0060041); syndromic X-linked intellectual disability Claes-Jensen type (Disease Ontology:DOID:0060809); autosomal recessive intellectual developmental disorder 65 (Disease Ontology:DOID:0081226); prostate cancer (Disease Ontology:DOID:10283); stomach cancer (Disease Ontology:DOID:10534); intellectual disability (Disease Ontology:DOID:1059); urinary bladder cancer (Disease Ontology:DOID:11054); cryptorchidism (Disease Ontology:DOID:11383); descending colon cancer (Disease Ontology:DOID:12190); Huntington's disease (Disease Ontology:DOID:12858); alcohol use disorder (Disease Ontology:DOID:1574); breast cancer (Disease Ontology:DOID:1612); colon cancer (Disease Ontology:DOID:219); high grade glioma (Disease Ontology:DOID:3070); esophagus squamous cell carcinoma (Disease Ontology:DOID:3748); lung non-small cell carcinoma (Disease Ontology:DOID:3908); schizophrenia (Disease Ontology:DOID:5419); stomach carcinoma (Disease Ontology:DOID:5517); uveal melanoma (Disease Ontology:DOID:6039); hepatocellular carcinoma (Disease Ontology:DOID:684); ankylosing spondylitis (Disease Ontology:DOID:7147); colorectal cancer (Disease Ontology:DOID:9256); alopecia areata (Disease Ontology:DOID:986)", "pathway": " (dme:Dmel_CG9088); (R-DME-8866911)", "pathway_count": 2, "publication_count": 20, "publication_id_list": "10731132;11014813;12537568;12537569;12537572;12537573;12537574;16110336;17311883;17351630;17351631;17372656;17569856;17569867;18327897;21960634;25589440;26109356;26109357;35916866", "class_list": "", "function": "Histone demethylase that specifically demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'. Specifically demethylates trimethylated H3 'Lys-4'. Required for the correct regulation of homeotic genes during development. Plays a role in the regulation of the circadian rhythm and in maintaining the normal periodicity of the circadian clock. Regulates the expression of clock-controlled genes including tim, per and cry., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 7, "predicted_n_glycosites": 0, "predicted_o_glycosites": 7, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 24, "glyco_site_count": 7, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.14.11.67", "go_molecular_function": "GO:0034647 histone H3K4me/H3K4me2/H3K4me3 demethylase activity;GO:0033749 histone H4R3 demethylase activity;GO:0003677 DNA binding;GO:0004857 enzyme inhibitor activity;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005634 nucleus;GO:0000785 chromatin;GO:0070822 Sin3-type complex;GO:0005654 nucleoplasm", "go_biological_process": "GO:0006338 chromatin remodeling;GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0006355 regulation of DNA-templated transcription;GO:0048149 behavioral response to ethanol", "synthesized_glycan_count": 0, "hit_score": 2.1, "record_id": "Q9VMJ7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VKJ9-1", "uniprot_id": "C2D1_DROME", "mass": 89038.0, "length": 816, "protein_name": "Coiled-coil and C2 domain-containing protein 1-like", "gene_name": "l(2)gd1", "organism": "Fruit fly", "refseq_name": "lethal (2) giant discs 1, isoform A", "refseq_ac": "NP_609488", "gene_names_uniprotkb": "l(2)gd1; CG4713; Dmel\\CG4713; Dmel_CG4713; Lgd; SH495; gd; l(2)SH0495; l(2)SH2 0495; l(2)gd; l(2)giant disc; l[[2]]gd; lgd", "gene_names_refseq": "CG4713; Dmel\\CG4713; Lgd; SH495; gd; l(2)SH0495; l(2)SH2 0495; l(2)gd1; l(2)gd; l(2)giant disc; l[[2]]gd; lgd", "protein_names_uniprotkb": "Coiled-coil and C2 domain-containing protein 1-like; Lethal (2) giant discs 1 protein", "protein_names_refseq": "CG4713-PA; l(2)gd1-PA; leathal giant disc; lethal (2) SH0495; lethal (2) giant discs 1, isoform A; lethal (2) giant discs; lethal giant discs; lethal(2) giant discs; lethal(2)giant discs 1", "tax_id": 7227, "disease": "visceral heterotaxy (Disease Ontology:DOID:0050545); syndromic intellectual disability (Disease Ontology:DOID:0050888); ciliopathy (Disease Ontology:DOID:0060340); autosomal recessive intellectual developmental disorder 3 (Disease Ontology:DOID:0081179); intellectual disability (Disease Ontology:DOID:1059)", "pathway": " (dme:Dmel_CG4713); (R-DME-9668328)", "pathway_count": 2, "publication_count": 24, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;12648493;16110336;17084357;17084358;17088062;17569856;17569867;22389409;23178945;25589440;25647097;25804739;26109356;26109357;27452459;28564595;30513301;33349255", "class_list": "", "function": "Phosphatidyl inositol monophosphate binding protein involved in endosomal protein sorting through regulation of the endosomal sorting required for transport (ESCRT) pathway (PubMed:17084357, PubMed:28564595, PubMed:33349255). Required for full activity of the ESCRT-III complex core component shrb/shrub, probably by preventing its inappropriate polymerization (PubMed:28564595, PubMed:33349255). Required, but not essential, for the efficient generation of intraluminal vesicles (ILVs) in multivesicular bodies (MVBs) (PubMed:33349255). Involved in a late stage of the endosomal pathway targeting transmembrane proteins of the plasma membrane for lysosomal degradation (PubMed:17084357, PubMed:17084358, PubMed:17088062, PubMed:23178945, PubMed:25804739). Plays a critical role in regulation of multiple signal transduction pathways, including the Notch and BMP/decapentaplegic (dpp) signaling pathways, through targeting of membrane bound receptors to multivesicular bodies, isolating them from the cytoplasm and targeting them for lysosomal degradation (PubMed:12648493, PubMed:17084357, PubMed:17084358, PubMed:17088062, PubMed:25804739). Involved in targeting N/Notch for endosomal degradation, negatively regulating the Notch signaling pathway (PubMed:12648493, PubMed:17084357, PubMed:17084358, PubMed:17088062). Regulates Notch signaling in imaginal disk cells and follicle cells during oogenesis and multiple developmental processes, including development of wings, veins, legs, eyes and bristles (PubMed:17084358, PubMed:23178945). Restricts the activity of Notch to the dorsoventral (D/V) boundary of the wing imaginal disk (PubMed:12648493, PubMed:17088062, PubMed:28564595). In external sensory organ development regulates Notch signaling during asymmetric cell division and differentiation of sensory organ precursor cells (PubMed:17084357). May be involved in regulation of apoptosis and cell growth independent of Notch signaling (PubMed:17084358). Involved in targeting tkv for endosomal degradation, negatively regulating the BMP/decapentaplegic (dpp) signaling pathway (PubMed:25804739). Regulates the BMP/dpp signaling pathway in follicle cells during oogenesis, but not in imaginal disk cells during wing development (PubMed:25804739). May be involved in differentiation or morphogenesis of peripodial epithelial cells in the developing imaginal disk (PubMed:23178945). Involved in abscission of germline cells during oogenesis (PubMed:25647097)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 7, "predicted_n_glycosites": 0, "predicted_o_glycosites": 7, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 6, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 7, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:1901981 phosphatidylinositol phosphate binding", "go_cellular_component": "GO:0098592 cytoplasmic side of apical plasma membrane;GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005938 cell cortex", "go_biological_process": "GO:0048749 compound eye development;GO:0006357 regulation of transcription by RNA polymerase II;GO:0006886 intracellular protein transport;GO:0007219 Notch signaling pathway;GO:0016197 endosomal transport", "synthesized_glycan_count": 0, "hit_score": 2.5, "record_id": "Q9VKJ9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VZA4-1", "uniprot_id": "BND7A_DROME", "mass": 57526.0, "length": 505, "protein_name": "Band 7 protein CG42540", "gene_name": "CG13719; CG32245; CG7468", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform C", "refseq_ac": "NP_647917", "gene_names_uniprotkb": "CG13719; CG32245; CG7468; CG13718; CG13719; CG32245; CG42540; CG7468; Dmel\\CG42540; Dmel_CG42540", "gene_names_refseq": "CG13718; CG13719; CG32245; CG42540; CG7468; Dmel\\CG42540", "protein_names_uniprotkb": "Band 7 protein CG42540", "protein_names_refseq": "CG42540-PC; uncharacterized protein, isoform C", "tax_id": 7227, "disease": "nephrotic syndrome type 2 (Disease Ontology:DOID:0080379)", "pathway": " (dme:Dmel_CG42540)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17018572;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q5BI93;Q8IRA9;Q8T0L0;Q95SR9;Q9VZA3", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "Q9VZA4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VQC4-1", "uniprot_id": "GLCTK_DROME", "mass": 52792.0, "length": 487, "protein_name": "Glycerate kinase", "gene_name": "AAF51252; Glyctk", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform B", "refseq_ac": "NP_001259941", "gene_names_uniprotkb": "AAF51252; Glyctk; CG9886; Dmel\\CG9886; Dmel_CG9886", "gene_names_refseq": "AAF51252; CG9886; Dmel\\CG9886", "protein_names_uniprotkb": "Glycerate kinase; 2.7.1.31", "protein_names_refseq": "CG9886-PB; uncharacterized protein, isoform B", "tax_id": 7227, "disease": "D-glyceric aciduria (Disease Ontology:DOID:0111626)", "pathway": " (dme:Dmel_CG9886); (R-DME-70350)", "pathway_count": 2, "publication_count": 12, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.1.31", "go_molecular_function": "GO:0008887 glycerate kinase activity;GO:0005524 ATP binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005829 cytosol", "go_biological_process": "GO:0006468 protein phosphorylation", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "Q9VQC4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VMA2-1", "uniprot_id": "GALT_DROME", "mass": 40447.0, "length": 350, "protein_name": "Probable galactose-1-phosphate uridylyltransferase", "gene_name": "Galt", "organism": "Fruit fly", "refseq_name": "Galactose-1-phosphate uridylyltransferase, isoform B", "refseq_ac": "NP_001260142", "gene_names_uniprotkb": "Galt; CG9232; Dmel\\CG9232; Dmel_CG9232; GALT; dGALT", "gene_names_refseq": "CG9232; Dmel\\CG9232; GALT; Galt; dGALT", "protein_names_uniprotkb": "Probable galactose-1-phosphate uridylyltransferase; 2.7.7.12; Gal-1-P uridylyltransferase; UDP-glucose--hexose-1-phosphate uridylyltransferase", "protein_names_refseq": "CG9232-PB; Galactose-1-phosphate uridylyltransferase, isoform B; Galt-PB; galactose-1-phosphate uridyltransferase; galactose-1-phosphate uridylyltransferase; galactose-1P uridylyltransferase", "tax_id": 7227, "disease": "classic galactosemia (Disease Ontology:DOID:0111459); galactosemia (Disease Ontology:DOID:9870)", "pathway": " (dme:Dmel_CG9232); (R-DME-70370)", "pathway_count": 2, "publication_count": 12, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "B9EQS8;Q8SXN7", "ec_number_list": "2.7.7.12", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0008108 UDP-glucose:hexose-1-phosphate uridylyltransferase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0033499 galactose catabolic process via UDP-galactose, Leloir pathway;GO:0006011 UDP-alpha-D-glucose metabolic process;GO:0006012 galactose metabolic process;GO:0052573 UDP-D-galactose metabolic process;GO:0052574 UDP-galactose biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "Q9VMA2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VKY2-1", "uniprot_id": "CAND1_DROME", "mass": 139355.0, "length": 1248, "protein_name": "Cullin-associated NEDD8-dissociated protein 1", "gene_name": "Cand1", "organism": "Fruit fly", "refseq_name": "Cullin-associated and neddylation-dissociated 1, isoform B", "refseq_ac": "NP_001260333", "gene_names_uniprotkb": "Cand1; BcDNA:GH07774; CAND1; CG5366; Dmel\\CG5366; Dmel_CG5366; dmCAND1", "gene_names_refseq": "BcDNA:GH07774; CAND1; CG5366; Cand1; Dmel\\CG5366; dmCAND1", "protein_names_uniprotkb": "Cullin-associated NEDD8-dissociated protein 1; Cullin-associated and neddylation-dissociated protein 1", "protein_names_refseq": "CG5366-PB; Cand1-PB; Cullin-associated and neddylation-dissociated 1, isoform B", "tax_id": 7227, "disease": "cancer (Disease Ontology:DOID:162)", "pathway": " (dme:Dmel_CG5366); (R-DME-6798695); (R-DME-8951664); (R-DME-917937)", "pathway_count": 4, "publication_count": 12, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;20691177;25589440;26109356;26109357", "class_list": "", "function": "Key assembly factor of SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes that promotes the exchange of the substrate-recognition F-box subunit in SCF complexes, thereby playing a key role in the cellular repertoire of SCF complexes. Acts as a F-box protein exchange factor. Probably plays a similar role in other cullin-RING E3 ubiquitin ligase complexes (Probable)., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q4QQA6;Q9Y127", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0031647 regulation of protein stability;GO:0016567 protein ubiquitination;GO:2000435 negative regulation of protein neddylation;GO:0010265 SCF complex assembly", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "Q9VKY2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VKX7-1", "uniprot_id": "ALG6_DROME", "mass": 53653.0, "length": 475, "protein_name": "Probable dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase", "gene_name": "gny", "organism": "Fruit fly", "refseq_name": "garnysstan, isoform B", "refseq_ac": "NP_001260338", "gene_names_uniprotkb": "gny; Alg6; CG5091; Dalg6; Dmel\\CG5091; Dmel_CG5091; Gny[; alg6; dAlg6", "gene_names_refseq": "CG5091; Dalg6; Dmel\\CG5091; Gny[; alg6; dAlg6; gny", "protein_names_uniprotkb": "Probable dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase; 2.4.1.267; Asparagine-linked glycosylation protein 6 homolog; Dol-P-Glc:Man(9)GlcNAc(2)-PP-Dol alpha-1,3-glucosyltransferase; Dolichyl-P-Glc:Man9GlcNAc2-PP-dolichyl glucosyltransferase", "protein_names_refseq": "CG5091-PB; garnysstan, isoform B; gny-PB", "tax_id": 7227, "disease": "congenital disorder of glycosylation type I (Disease Ontology:DOID:0050570); congenital disorder of glycosylation Ic (Disease Ontology:DOID:0080555)", "pathway": " (dme:Dmel_CG5091); (R-DME-446193)", "pathway_count": 2, "publication_count": 13, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;21199819;25589440;26109356;26109357", "class_list": "", "function": "Adds the first glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Man(9)GlcNAc(2)-PP-Dol. Involved in cuticle differentiation., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q960Z1", "ec_number_list": "2.4.1.-;2.4.1.267", "go_molecular_function": "GO:0042281 dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity;GO:0016758 hexosyltransferase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006488 dolichol-linked oligosaccharide biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "Q9VKX7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9W0K4-1", "uniprot_id": "BAB2_DROME", "mass": 114662.0, "length": 1067, "protein_name": "Protein bric-a-brac 2", "gene_name": "bab2", "organism": "Fruit fly", "refseq_name": "bric a brac 2, isoform A", "refseq_ac": "NP_523879", "gene_names_uniprotkb": "bab2; BAB2; BAB; BTB-II; Bab2; BtbII; CG13911; CG9102; Dmel\\CG9102; Dmel_CG9102; bab-II; bab", "gene_names_refseq": "BAB2; BAB; BTB-II; Bab2; BtbII; CG13911; CG9102; Dmel\\CG9102; bab-II; bab2; bab", "protein_names_uniprotkb": "Protein bric-a-brac 2", "protein_names_refseq": "BTB-protein-II; Bric-a-brac 2; CG9102-PA; bab2-PA; bric a brac 2, isoform A; bric a brac II; bric a brac; bric-a-brac-2; bric-a-brac2", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG9102)", "pathway_count": 1, "publication_count": 15, "publication_id_list": "10731132;11973274;12537568;12537572;12537573;12537574;16110336;17569856;17569867;18327897;25589440;26109356;26109357;40245499;7938017", "class_list": "", "function": "Probably acts as a transcriptional regulator. Required for the specification of the tarsal segment. Also involved in antenna development., [UniProtKB, PubMed, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "Q24001;Q7YU69;Q9U1H3", "ec_number_list": "", "go_molecular_function": "GO:0003680 minor groove of adenine-thymine-rich DNA binding;GO:0003700 DNA-binding transcription factor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005700 polytene chromosome", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0006355 regulation of DNA-templated transcription;GO:0061040 female gonad morphogenesis;GO:0007455 eye-antennal disc morphogenesis", "synthesized_glycan_count": 0, "hit_score": 1.8, "record_id": "Q9W0K4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VZW5-1", "uniprot_id": "FMAR_DROME", "mass": 61755.0, "length": 549, "protein_name": "FMRFamide receptor", "gene_name": "FMRFaR", "organism": "Fruit fly", "refseq_name": "FMRFamide receptor, isoform B", "refseq_ac": "NP_001261347", "gene_names_uniprotkb": "FMRFaR; CG2114; Dm FMRFa-R; DmFR; Dmel\\CG2114; Dmel_CG2114; DrmFMRFa-R; FMRFa-R; FR; Fmrf R", "gene_names_refseq": "CG2114; Dm FMRFa-R; DmFR; Dmel\\CG2114; DrmFMRFa-R; FMRFa-R; FMRFaR; FR; Fmrf R", "protein_names_uniprotkb": "FMRFamide receptor; DFR; DrmFMRFa-R", "protein_names_refseq": "CG2114-PB; FMRFa receptor; FMRFa-receptor; FMRFaR-PB; FMRFamide receptor, isoform B; FMRFamide receptor; dFMRFa receptor; fmrf receptor; larval-opioid-receptor", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG2114)", "pathway_count": 1, "publication_count": 14, "publication_id_list": "10731132;12218185;12438685;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357;30110323", "class_list": "", "function": "A receptor for the FMRFamide peptides (PubMed:12218185, PubMed:12438685). Reacts with high affinity to FMRFamide and intrinsic FMRFamide-related peptides (PubMed:12218185, PubMed:12438685). By stimulating intracellular calcium signaling through the inositol 1,4,5-trisphosphate receptor, Itpr, in dopaminergic neurons, may be involved in the maintenance of neuronal excitability and in the regulation of flight bout duration (PubMed:30110323)., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008188 neuropeptide receptor activity;GO:0001653 peptide receptor activity;GO:0004930 G protein-coupled receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway;GO:0007204 positive regulation of cytosolic calcium ion concentration;GO:0007218 neuropeptide signaling pathway;GO:0008344 adult locomotory behavior;GO:0032226 positive regulation of synaptic transmission, dopaminergic", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "Q9VZW5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VQ57-1", "uniprot_id": "DERL1_DROME", "mass": 28256.0, "length": 245, "protein_name": "Derlin-1", "gene_name": "Der-1", "organism": "Fruit fly", "refseq_name": "Derlin-1, isoform B", "refseq_ac": "NP_001259892", "gene_names_uniprotkb": "Der-1; CG10908; Dmel\\CG10908; Dmel_CG10908; dDer-1; l(2)SH1964; l(2)SH2 1964", "gene_names_refseq": "CG10908; Der-1; Dmel\\CG10908; dDer-1; l(2)SH1964; l(2)SH2 1964", "protein_names_uniprotkb": "Derlin-1; DER1-like protein 1", "protein_names_refseq": "CG10908-PB; Der-1-PB; Derlin-1, isoform B; Dm Derlin-1; derlin-1; lethal (2) SH1964", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG10908); (R-DME-382556); (R-DME-532668)", "pathway_count": 3, "publication_count": 12, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins., [UniProtKB, UniProtKB]; May be involved in the degradation process of specific misfolded endoplasmic reticulum (ER) luminal proteins. May also involved in endoplasmic reticulum stress-induced pre-emptive quality control, a mechanism that selectively attenuates the translocation of newly synthesized proteins into the endoplasmic reticulum and reroutes them to the cytosol for proteasomal degradation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005047 signal recognition particle binding", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0043065 positive regulation of apoptotic process;GO:0030968 endoplasmic reticulum unfolded protein response;GO:0036503 ERAD pathway;GO:0034976 response to endoplasmic reticulum stress;GO:0006515 protein quality control for misfolded or incompletely synthesized proteins", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "Q9VQ57-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VQN8-1", "uniprot_id": "FIGL1_DROME", "mass": 58549.0, "length": 523, "protein_name": "Fidgetin-like protein 1", "gene_name": "Fign", "organism": "Fruit fly", "refseq_name": "fidgetin, isoform B", "refseq_ac": "NP_001259995", "gene_names_uniprotkb": "Fign; CG3326; DmCG3326; Dmel\\CG3326; Dmel_CG3326; fign", "gene_names_refseq": "CG3326; DmCG3326; Dmel\\CG3326; Fign; fign", "protein_names_uniprotkb": "Fidgetin-like protein 1; 3.6.4.-", "protein_names_refseq": "CG3326-PB; Dm-fidgetin; Fign-PB; fidgetin, isoform B; fidgetin_DROME", "tax_id": 7227, "disease": "nicotine dependence (Disease Ontology:DOID:0050742)", "pathway": " (dme:Dmel_CG3326)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q95TF9", "ec_number_list": "3.6.4.13;7.2.2.-;3.6.4.-;3.6.4.10;3.6.4.6;3.6.4.12;5.6.2.4;5.6.2.5;2.7.4.3;5.6.2.3;3.1.-.-;3.6.1.15;3.-.-.-;5.6.1.1;2.7.11.1;3.6.-.-;5.6.2.-", "go_molecular_function": "GO:0008568 microtubule severing ATPase activity;GO:0000287 magnesium ion binding;GO:0005524 ATP binding;GO:0016787 hydrolase activity;GO:0016887 ATP hydrolysis activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005813 centrosome;GO:0005694 chromosome", "go_biological_process": "GO:0051013 microtubule severing;GO:0009611 response to wounding;GO:0046034 ATP metabolic process;GO:0000070 mitotic sister chromatid segregation;GO:0031114 regulation of microtubule depolymerization", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "Q9VQN8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VQG2-1", "uniprot_id": "APH1_DROME", "mass": 26437.0, "length": 238, "protein_name": "Gamma-secretase subunit Aph-1", "gene_name": "aph-1", "organism": "Fruit fly", "refseq_name": "anterior pharynx defective 1, isoform B", "refseq_ac": "NP_001259963", "gene_names_uniprotkb": "aph-1; APH1; Aph-1; Aph1; CG2855; Dm APH-1; Dmel\\CG2855; Dmel_CG2855; PSF; Pen-1; aph1; aph; dAPH 1; dAPH1; dAph-1; l(2)23AB6; l(2)23Ag; pen-1", "gene_names_refseq": "APH1; Aph-1; Aph1; CG2855; Dm APH-1; Dmel\\CG2855; Pen-1; aph-1; aph1; aph; dAPH 1; dAPH1; dAph-1; l(2)23AB6; l(2)23Ag; pen-1", "protein_names_uniprotkb": "Gamma-secretase subunit Aph-1; Presenilin-stabilization factor", "protein_names_refseq": "CG2855-PB; anterior pharynx defective 1, isoform B; anterior pharynx defective 1; aph-1-PB; presenilin enhancer-1; presenilin stabilization factor", "tax_id": 7227, "disease": "coronary artery disease (Disease Ontology:DOID:3393)", "pathway": " (dme:Dmel_CG2855); (R-DME-1251985); (R-DME-3928665)", "pathway_count": 3, "publication_count": 14, "publication_id_list": "10731132;12110170;12537568;12537569;12537572;12537573;12537574;12660785;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch. It probably represents a stabilizing cofactor for the presenilin homodimer that promotes the formation of a stable complex., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0030674 protein-macromolecule adaptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane;GO:0055037 recycling endosome;GO:0005770 late endosome;GO:0070765 gamma-secretase complex", "go_biological_process": "GO:0035333 Notch receptor processing, ligand-dependent;GO:0006509 membrane protein ectodomain proteolysis;GO:0007219 Notch signaling pathway;GO:0007220 Notch receptor processing;GO:0016485 protein processing", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "Q9VQG2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VLJ6-1", "uniprot_id": "ACER_DROME", "mass": 73057.0, "length": 630, "protein_name": "Angiotensin-converting enzyme-related protein", "gene_name": "Acer", "organism": "Fruit fly", "refseq_name": "Angiotensin-converting enzyme-related, isoform B", "refseq_ac": "NP_001260258", "gene_names_uniprotkb": "Acer; ACER; ACE; CG10593; Dmel\\CG10593; Dmel_CG10593; acer; l(2)k07704", "gene_names_refseq": "ACER; ACE; Acer; CG10593; Dmel\\CG10593; acer; l(2)k07704", "protein_names_uniprotkb": "Angiotensin-converting enzyme-related protein; 3.4.15.1", "protein_names_refseq": "Acer-PB; Angiotensin-converting enzyme peptidase; Angiotensin-converting enzyme-related, isoform B; CG10593-PB; angiotensin-converting enzyme-related", "tax_id": 7227, "disease": "aspiration pneumonia (Disease Ontology:DOID:0050152); obstructive sleep apnea (Disease Ontology:DOID:0050848); glomerulosclerosis (Disease Ontology:DOID:0050851); renal fibrosis (Disease Ontology:DOID:0050855); non-arteritic anterior ischemic optic neuropathy (Disease Ontology:DOID:0050864); coarctation of the aorta (Disease Ontology:DOID:0051054); stroke (Disease Ontology:DOID:0051061); pre-malignant neoplasm (Disease Ontology:DOID:0060071); atrial fibrillation (Disease Ontology:DOID:0060224); thrombosis (Disease Ontology:DOID:0060903); alcohol-associated liver disease (Disease Ontology:DOID:0070658); Coronavirus infectious disease (Disease Ontology:DOID:0080599); COVID-19 (Disease Ontology:DOID:0080600); autosomal recessive polycystic kidney disease (Disease Ontology:DOID:0110861); focal segmental glomerulosclerosis 1 (Disease Ontology:DOID:0111128); stomach cancer (Disease Ontology:DOID:10534); pre-eclampsia (Disease Ontology:DOID:10591); Alzheimer's disease (Disease Ontology:DOID:10652); hypertension (Disease Ontology:DOID:10763); nephritis (Disease Ontology:DOID:10952); IgA vasculitis (Disease Ontology:DOID:11123); sarcoidosis (Disease Ontology:DOID:11335); pyelonephritis (Disease Ontology:DOID:11400); osteoporosis (Disease Ontology:DOID:11476); diabetic angiopathy (Disease Ontology:DOID:11713); nephrotic syndrome (Disease Ontology:DOID:1184); hypertrophic cardiomyopathy (Disease Ontology:DOID:11984); allergic disease (Disease Ontology:DOID:1205); primary biliary cholangitis (Disease Ontology:DOID:12236); leukemia (Disease Ontology:DOID:1240); hepatitis A (Disease Ontology:DOID:12549); respiratory syncytial virus infectious disease (Disease Ontology:DOID:1273); endomyocardial fibrosis (Disease Ontology:DOID:12932); leukostasis (Disease Ontology:DOID:12986); uveitis (Disease Ontology:DOID:13141); lung cancer (Disease Ontology:DOID:1324); Behcet's disease (Disease Ontology:DOID:13241); cholestasis (Disease Ontology:DOID:13580); cerebral malaria (Disease Ontology:DOID:14069); toxic shock syndrome (Disease Ontology:DOID:14115); Fabry disease (Disease Ontology:DOID:14499); renovascular hypertension (Disease Ontology:DOID:1591); breast cancer (Disease Ontology:DOID:1612); glaucoma (Disease Ontology:DOID:1686); anemia (Disease Ontology:DOID:2355); nephrosis (Disease Ontology:DOID:2527); bronchiolitis obliterans (Disease Ontology:DOID:2799); asthma (Disease Ontology:DOID:2841); glomerulonephritis (Disease Ontology:DOID:2921); severe acute respiratory syndrome (Disease Ontology:DOID:2945); IgA glomerulonephritis (Disease Ontology:DOID:2986); familial Mediterranean fever (Disease Ontology:DOID:2987); acute kidney failure (Disease Ontology:DOID:3021); chronic obstructive pulmonary disease (Disease Ontology:DOID:3083); coronary artery disease (Disease Ontology:DOID:3393); gallbladder adenocarcinoma (Disease Ontology:DOID:3500); middle cerebral artery infarction (Disease Ontology:DOID:3525); cerebral infarction (Disease Ontology:DOID:3526); pancreatic ductal carcinoma (Disease Ontology:DOID:3587); pulmonary fibrosis (Disease Ontology:DOID:3770); congenital diaphragmatic hernia (Disease Ontology:DOID:3827); lung carcinoma (Disease Ontology:DOID:3905); heart valve disease (Disease Ontology:DOID:4079); systemic scleroderma (Disease Ontology:DOID:418); avian influenza (Disease Ontology:DOID:4492); liver cirrhosis (Disease Ontology:DOID:5082); ureteral obstruction (Disease Ontology:DOID:5199); schizophrenia (Disease Ontology:DOID:5419); pneumonia (Disease Ontology:DOID:552); proteinuria (Disease Ontology:DOID:576); myocardial infarction (Disease Ontology:DOID:5844); congestive heart failure (Disease Ontology:DOID:6000); mitral valve disease (Disease Ontology:DOID:61); pulmonary hypertension (Disease Ontology:DOID:6432); hepatocellular carcinoma (Disease Ontology:DOID:684); ankylosing spondylitis (Disease Ontology:DOID:7147); abdominal aortic aneurysm (Disease Ontology:DOID:7693); end stage renal disease (Disease Ontology:DOID:783); ocular hypotension (Disease Ontology:DOID:790); myocarditis (Disease Ontology:DOID:820); extrinsic allergic alveolitis (Disease Ontology:DOID:841); polycythemia (Disease Ontology:DOID:8432); lung disease (Disease Ontology:DOID:850); chronic myeloid leukemia (Disease Ontology:DOID:8552); intermediate coronary syndrome (Disease Ontology:DOID:8805); diabetic retinopathy (Disease Ontology:DOID:8947); subacute sclerosing panencephalitis (Disease Ontology:DOID:8970); type 2 diabetes mellitus (Disease Ontology:DOID:9352); multiple myeloma (Disease Ontology:DOID:9538); type 1 diabetes mellitus (Disease Ontology:DOID:9744); diastolic heart failure (Disease Ontology:DOID:9775); mitral valve prolapse (Disease Ontology:DOID:988); obesity (Disease Ontology:DOID:9970)", "pathway": " (dme:Dmel_CG10593); (R-DME-2022377)", "pathway_count": 2, "publication_count": 16, "publication_id_list": "10731132;12075344;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357;40245499;8973330;9839949", "class_list": "", "function": "May be involved in the specific maturation or degradation of a number of bioactive peptides. May have a role in the specification of heart progenitors., [UniProtKB, PubMed]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 93, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "Q24222", "ec_number_list": "3.4.-.-;3.4.15.1", "go_molecular_function": "GO:0004222 metalloendopeptidase activity;GO:0008237 metallopeptidase activity;GO:0008270 zinc ion binding;GO:0004180 carboxypeptidase activity;GO:0008241 peptidyl-dipeptidase activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0005615 extracellular space;GO:0005886 plasma membrane;GO:0016020 membrane", "go_biological_process": "GO:0006508 proteolysis;GO:0007507 heart development;GO:0045938 positive regulation of circadian sleep/wake cycle, sleep;GO:0003007 heart morphogenesis;GO:0002027 regulation of heart rate", "synthesized_glycan_count": 0, "hit_score": 1.9, "record_id": "Q9VLJ6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VLU0-1", "uniprot_id": "BAF_DROME", "mass": 10116.0, "length": 90, "protein_name": "Barrier-to-autointegration factor", "gene_name": "baf", "organism": "Fruit fly", "refseq_name": "barrier to autointegration factor, isoform B", "refseq_ac": "NP_001260220", "gene_names_uniprotkb": "baf; BAF; CG7380; Dmel\\CG7380; Dmel_CG7380; anon-WO0172774.178; dBAF", "gene_names_refseq": "BAF; CG7380; Dmel\\CG7380; anon-WO0172774.178; baf; dBAF", "protein_names_uniprotkb": "Barrier-to-autointegration factor", "protein_names_refseq": "Barrier-to-Autointegration factor; CG7380-PB; baf-PB; barrier to autointegration factor, isoform B", "tax_id": 7227, "disease": "Nestor-Guillermo progeria syndrome (Disease Ontology:DOID:0081334); hepatocellular carcinoma (Disease Ontology:DOID:684)", "pathway": " (dme:Dmel_CG7380); (R-DME-2995383)", "pathway_count": 2, "publication_count": 14, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;12902403;16110336;17569856;17569867;20036230;25589440;26109356;26109357;30309980", "class_list": "", "function": "Plays fundamental roles in nuclear assembly, chromatin organization, gene expression and gonad development. May potently compress chromatin structure and be involved in membrane recruitment and chromatin decondensation during nuclear assembly. Functions are required in both M phase and interphase of the cell cycle., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q53XE9", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005635 nuclear envelope;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0000793 condensed chromosome", "go_biological_process": "GO:0030261 chromosome condensation;GO:0051276 chromosome organization;GO:0030717 oocyte karyosome formation", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "Q9VLU0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VLS1-1", "uniprot_id": "KPBB_DROME", "mass": 124864.0, "length": 1093, "protein_name": "Probable phosphorylase b kinase regulatory subunit beta", "gene_name": "Dmel\\CG8475", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform A", "refseq_ac": "NP_609189", "gene_names_uniprotkb": "Dmel\\CG8475; CG8475; Dmel_CG8475", "gene_names_refseq": "CG8475; Dmel\\CG8475", "protein_names_uniprotkb": "Probable phosphorylase b kinase regulatory subunit beta; Phosphorylase kinase subunit beta", "protein_names_refseq": "CG8475-PA; uncharacterized protein, isoform A", "tax_id": 7227, "disease": "glycogen storage disease IXb (Disease Ontology:DOID:0111041)", "pathway": " (dme:Dmel_CG8475); (R-DME-70221)", "pathway_count": 2, "publication_count": 13, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357;40245499", "class_list": "", "function": "Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "F9VMG4;Q8IPG3;Q8SXP4", "ec_number_list": "", "go_molecular_function": "GO:0005516 calmodulin binding", "go_cellular_component": "GO:0005964 phosphorylase kinase complex;GO:0005886 plasma membrane", "go_biological_process": "GO:0045819 positive regulation of glycogen catabolic process;GO:0005977 glycogen metabolic process", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "Q9VLS1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VVV9-1", "uniprot_id": "NKD_DROME", "mass": 102601.0, "length": 928, "protein_name": "Protein naked cuticle", "gene_name": "nkd", "organism": "Fruit fly", "refseq_name": "naked cuticle, isoform A", "refseq_ac": "NP_524788", "gene_names_uniprotkb": "nkd; CG11614; CG18224; Dmel\\CG11614; Dmel_CG11614; Nkd; naked", "gene_names_refseq": "CG11614; CG18224; Dmel\\CG11614; Nkd; naked; nkd", "protein_names_uniprotkb": "Protein naked cuticle; dNkd", "protein_names_refseq": "CG11614-PA; naked cuticle, isoform A; naked cuticle; nkd-PA", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG11614)", "pathway_count": 1, "publication_count": 20, "publication_id_list": "10693810;10731132;11274052;11356022;11546742;12354775;12537568;12537569;12537572;12537573;12537574;15695356;16110336;16849595;17569856;17569867;18327897;25589440;26109356;26109357", "class_list": "", "function": "Cell autonomous antagonist of the canonical Wnt signaling pathway., [UniProtKB, UniProtKB, UniProtKB]; Cell autonomous antagonist of the canonical Wnt signaling pathway. May activate a second Wnt signaling pathway that controls planar cell polarity. Required for neuroblast specification., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q95RL6;Q9NIH2;Q9VVW0", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0030165 PDZ domain binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005886 plasma membrane", "go_biological_process": "GO:0090090 negative regulation of canonical Wnt signaling pathway;GO:0016055 Wnt signaling pathway;GO:0030178 negative regulation of Wnt signaling pathway;GO:0090263 positive regulation of canonical Wnt signaling pathway;GO:0007367 segment polarity determination", "synthesized_glycan_count": 0, "hit_score": 2.1, "record_id": "Q9VVV9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VPH7-1", "uniprot_id": "ERF1_DROME", "mass": 49160.0, "length": 438, "protein_name": "Eukaryotic peptide chain release factor subunit 1", "gene_name": "eRF1", "organism": "Fruit fly", "refseq_name": "eukaryotic translation release factor 1, isoform A", "refseq_ac": "NP_649210", "gene_names_uniprotkb": "eRF1; CG5605; Dm0184; Dmel\\CG5605; Dmel_CG5605; Group J; deRF1; group J; l(3)00103; l(3)05637; l(3)77ABb; l(3)neo28", "gene_names_refseq": "CG5605; Dm0184; Dmel\\CG5605; Group J; deRF1; eRF1; group J; l(3)00103; l(3)05637; l(3)77ABb; l(3)neo28", "protein_names_uniprotkb": "Eukaryotic peptide chain release factor subunit 1; Eukaryotic release factor 1; eRF1", "protein_names_refseq": "CG5605-PA; eRF1-PA; eukaryotic release factor 1; eukaryotic translation release factor 1, isoform A", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG5605); (R-DME-72764); (R-DME-9629569); (R-DME-975956); (R-DME-975957)", "pathway_count": 5, "publication_count": 13, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;18327897;25589440;26109356;26109357", "class_list": "", "function": "Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A4V259;Q0E8C7;Q8T071", "ec_number_list": "", "go_molecular_function": "GO:1990825 sequence-specific mRNA binding;GO:0016149 translation release factor activity, codon specific;GO:0003747 translation release factor activity", "go_cellular_component": "GO:0018444 translation release factor complex;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0002184 cytoplasmic translational termination;GO:0006415 translational termination", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "Q9VPH7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VIP7-1", "uniprot_id": "ACASE_DROME", "mass": 32793.0, "length": 283, "protein_name": "Inactive alkaline ceramidase", "gene_name": "bwa", "organism": "Fruit fly", "refseq_name": "brain washing, isoform A", "refseq_ac": "NP_610020", "gene_names_uniprotkb": "bwa; 38B.6; ACER; BWA; CG13969; Dacer; DmACER; Dmel\\CG13969; Dmel_CG13969; dacer", "gene_names_refseq": "38B.6; ACER; BWA; CG13969; Dacer; DmACER; Dmel\\CG13969; bwa; dacer", "protein_names_uniprotkb": "Inactive alkaline ceramidase; AlkCDase; Alkaline N-acylsphingosine amidohydrolase; Alkaline acylsphingosine deacylase; Dacer; Protein brain washing", "protein_names_refseq": "CG13969-PA; alkaline ceramidase; brain washing, isoform A; brain washing; brainwashing; bwa-PA; dacer", "tax_id": 7227, "disease": "leukodystrophy (Disease Ontology:DOID:10579)", "pathway": " (dme:Dmel_CG13969); (R-DME-9845614)", "pathway_count": 2, "publication_count": 18, "publication_id_list": "10623899;10731132;12537568;12537569;12537572;12537573;12537574;14516700;16110336;17569856;17569867;20112046;21148295;25589440;26109356;26109357;31115476;33590535", "class_list": "", "function": "Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid., [UniProtKB, UniProtKB]; Regulator of the sphingolipid biosynthetic pathway controlling ceramide levels; pseudoenzyme that lacks ceramidase activity (PubMed:20112046, PubMed:21148295). May be involved in regulating juvenile hormone levels (PubMed:20112046). May affect mitochondrial metabolic function and reactive oxygen species (ROS) production (PubMed:20112046). May regulate expression of proteins involved in the oxidative stress response (PubMed:31115476)., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q8SYZ0;Q8WSF4", "ec_number_list": "", "go_molecular_function": "GO:0016787 hydrolase activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0016020 membrane", "go_biological_process": "GO:0006665 sphingolipid metabolic process;GO:0019216 regulation of lipid metabolic process;GO:0046514 ceramide catabolic process;GO:0007420 brain development;GO:0006672 ceramide metabolic process", "synthesized_glycan_count": 0, "hit_score": 1.9, "record_id": "Q9VIP7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VSY4-1", "uniprot_id": "ATAT1_DROME", "mass": 50560.0, "length": 461, "protein_name": "Alpha-tubulin N-acetyltransferase 1", "gene_name": "Atat", "organism": "Fruit fly", "refseq_name": "alpha-tubulin acetylase, isoform F", "refseq_ac": "NP_001261628", "gene_names_uniprotkb": "Atat; ATAT; Atat1; CG3967; Dmel\\CG3967; Dmel_CG3967; Tat; alphaTAT; dTAT; dTat; dalphaTAT", "gene_names_refseq": "ATAT; Atat1; Atat; CG3967; Dmel\\CG3967; Tat; alphaTAT; dTAT; dTat; dalphaTAT", "protein_names_uniprotkb": "Alpha-tubulin N-acetyltransferase 1; 2.3.1.108; Acetyltransferase mec-17 homolog 1; Alpha-TAT 1; TAT 1", "protein_names_refseq": "Atat-PF; CG3967-PF; alpha-tubulin acetylase, isoform F; alpha-tubulin acetyltransferase", "tax_id": 7227, "disease": "neurodegenerative disease (Disease Ontology:DOID:1289)", "pathway": " (dme:Dmel_CG3967)", "pathway_count": 1, "publication_count": 14, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357;36302967;40245499", "class_list": "", "function": "Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules (By similarity) (PubMed:36302967). Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dynamically unstable microtubules before the enzyme is released (By similarity). Acetylates central spindle microtubules (PubMed:36302967)., [UniProtKB, HAMAP, PubMed]; Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dynamically unstable microtubules before the enzyme is released., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q95S14;Q9VSY5", "ec_number_list": "2.3.1.108", "go_molecular_function": "GO:0019799 tubulin N-acetyltransferase activity", "go_cellular_component": "GO:0005874 microtubule", "go_biological_process": "GO:0048149 behavioral response to ethanol;GO:0000226 microtubule cytoskeleton organization;GO:0048666 neuron development;GO:0070507 regulation of microtubule cytoskeleton organization", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "Q9VSY4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VSL7-1", "uniprot_id": "FOI_DROME", "mass": 77376.0, "length": 706, "protein_name": "Zinc transporter foi", "gene_name": "foi", "organism": "Fruit fly", "refseq_name": "fear-of-intimacy, isoform B", "refseq_ac": "NP_001261584", "gene_names_uniprotkb": "foi; CG6817; Dmel\\CG6817; Dmel_CG6817; FOI; Foi; cg6817; dFOI; dZIPFoi; dZIPfoi; dZipFOI; kas; l(3)j8E8; l(3)neo13", "gene_names_refseq": "CG6817; Dmel\\CG6817; FOI; Foi; cg6817; dFOI; dZIPFoi; dZIPfoi; dZipFOI; foi; kas; l(3)j8E8; l(3)neo13", "protein_names_uniprotkb": "Zinc transporter foi; Protein fear-of-intimacy; Protein kastchen", "protein_names_refseq": "CG6817-PB; fear of intimacy; fear-of-intimacy, isoform B; foi-PB; kastchen", "tax_id": 7227, "disease": "idiopathic scoliosis (Disease Ontology:DOID:0060250); myopia (Disease Ontology:DOID:11830)", "pathway": " (dme:Dmel_CG6817); (R-DME-442380)", "pathway_count": 2, "publication_count": 15, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;12702650;15464587;15509557;16110336;17569856;17569867;18327897;25589440;26109356;26109357", "class_list": "", "function": "Required for the normal migration of longitudinal and peripheral glial cells. During larval development, required for the migration of the subretinal glia into the eye disk. During embryonic development, also controls the migration of muscle cells toward their attachment sites. Required in the mesoderm for the correct morphogenesis of embryonic gonad and for tracheal branch fusion during tracheal development. Shg may be cooperating with foi to mediate a common mechanism for gonad and tracheal morphogenesis. Acts as a zinc transporter in both yeast and mammalian cells., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 6, "predicted_n_glycosites": 6, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 6, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 6, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005385 zinc ion transmembrane transporter activity;GO:0140410 monoatomic cation:bicarbonate symporter activity;GO:0046873 metal ion transmembrane transporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0009986 cell surface;GO:0016323 basolateral plasma membrane;GO:0016020 membrane", "go_biological_process": "GO:0071577 zinc ion transmembrane transport;GO:0006829 zinc ion transport;GO:0016477 cell migration;GO:0030154 cell differentiation;GO:0007417 central nervous system development", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "Q9VSL7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VTC2-1", "uniprot_id": "BL1S4_DROME", "mass": 18851.0, "length": 169, "protein_name": "Biogenesis of lysosome-related organelles complex 1 subunit 4", "gene_name": "Blos4", "organism": "Fruit fly", "refseq_name": "biogenesis of lysosome-related organelles complex 1, subunit 4, isoform B", "refseq_ac": "NP_001261689", "gene_names_uniprotkb": "Blos4; CG14149; Dm Blos4; Dmel\\CG14149; Dmel_CG14149; NP_648414; blos4", "gene_names_refseq": "Blos4; CG14149; Dm Blos4; Dmel\\CG14149; NP_648414; blos4", "protein_names_uniprotkb": "Biogenesis of lysosome-related organelles complex 1 subunit 4; BLOC-1 subunit 4; Protein cappuccino homolog", "protein_names_refseq": "BLOC-1 subunit 4; Blos4-PB; CG14149-PB; biogenesis of lysosome-related organelles complex 1, subunit 4, isoform B; cappuccino", "tax_id": 7227, "disease": "Hermansky-Pudlak syndrome (Disease Ontology:DOID:3753)", "pathway": " (dme:Dmel_CG14149)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;20015953;25589440;26109356;26109357", "class_list": "", "function": "Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1) involved in pigment granule biogenesis., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0031083 BLOC-1 complex", "go_biological_process": "GO:0008057 eye pigment granule organization", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "Q9VTC2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VSF4-1", "uniprot_id": "DHYS_DROME", "mass": 41080.0, "length": 368, "protein_name": "Probable deoxyhypusine synthase", "gene_name": "Dhps", "organism": "Fruit fly", "refseq_name": "deoxyhypusine synthase, isoform A", "refseq_ac": "NP_648188", "gene_names_uniprotkb": "Dhps; CG8005; Dmel\\CG8005; Dmel_CG8005; dhs", "gene_names_refseq": "CG8005; Dhps; Dmel\\CG8005; dhs", "protein_names_uniprotkb": "Probable deoxyhypusine synthase; 2.5.1.46; DHS", "protein_names_refseq": "CG8005-PA; Dhps-PA; deoxyhypusine synthase, isoform A; deoxyhypusine synthase", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG8005); (R-DME-204626)", "pathway_count": 2, "publication_count": 12, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357;40245499", "class_list": "", "function": "Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.5.1.46", "go_molecular_function": "GO:0034038 deoxyhypusine synthase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0008216 spermidine metabolic process;GO:0051604 protein maturation", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "Q9VSF4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VUQ5-1", "uniprot_id": "AGO2_DROME", "mass": 136850.0, "length": 1214, "protein_name": "Protein argonaute-2", "gene_name": "AGO2", "organism": "Fruit fly", "refseq_name": "argonaute 2, isoform B", "refseq_ac": "NP_648775", "gene_names_uniprotkb": "AGO2; AG02; AGO 2; AGO-2; AGO1; Ago-2; Ago2a; Ago2; CG13452; CG7439; Dm Ago2; DmAgo2; Dmel\\CG7439; Dmel_CG7439; ago-2; ago2; ago; argonaute2; dAGO2; dAgo2; eIF2C2", "gene_names_refseq": "AG02; AGO 2; AGO-2; AGO1; AGO2; Ago-2; Ago2a; Ago2; CG13452; CG7439; Dm Ago2; DmAgo2; Dmel\\CG7439; ago-2; ago2; ago; argonaute2; dAGO2; dAgo2; eIF2C2", "protein_names_uniprotkb": "Protein argonaute-2", "protein_names_refseq": "AGO2-PB; ARGONAUTE2; CG7439-PB; argonaute 2, isoform B; argonaute 2; argonaute-2", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG7439); (R-DME-203927); (R-DME-426486); (R-DME-426496); (R-DME-5578749)", "pathway_count": 5, "publication_count": 23, "publication_id_list": "10731132;11498593;12368261;12537568;12537569;12537572;12537573;12537574;14508492;14615801;14625589;15156196;16110336;16546082;17178403;17569856;17569867;20400949;25589440;26109356;26109357;26257286;32504809", "class_list": "", "function": "Essential for RNA interference (RNAi); double-stranded RNA induces potent and specific gene silencing (PubMed:11498593, PubMed:12368261, PubMed:14508492, PubMed:32504809). RNAi is mediated by the RNA-induced silencing complex (RISC), a sequence-specific, multicomponent nuclease that destroys or silences messenger RNAs homologous to the silencing trigger (PubMed:11498593, PubMed:12368261, PubMed:14508492)., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "C7LAD2;Q2Q3Y0;Q2Q3Y1;Q2Q3Y3;Q2Q3Y4;Q2Q3Y5;Q86P07;Q8T3N2;Q9VUQ6", "ec_number_list": "", "go_molecular_function": "GO:0046872 metal ion binding;GO:0003727 single-stranded RNA binding;GO:0035198 miRNA binding;GO:0004521 RNA endonuclease activity;GO:0035197 siRNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0036464 cytoplasmic ribonucleoprotein granule;GO:0016442 RISC complex", "go_biological_process": "GO:0070922 RISC complex assembly;GO:0051607 defense response to virus;GO:0045071 negative regulation of viral genome replication;GO:0035194 regulatory ncRNA-mediated post-transcriptional gene silencing;GO:0030422 siRNA processing", "synthesized_glycan_count": 0, "hit_score": 2.4, "record_id": "Q9VUQ5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VVW5-1", "uniprot_id": "DUSK3_DROME", "mass": 45792.0, "length": 411, "protein_name": "Dual specificity protein phosphatase Mpk3", "gene_name": "Mkp3", "organism": "Fruit fly", "refseq_name": "Mitogen-activated protein kinase phosphatase 3, isoform D", "refseq_ac": "NP_001262032", "gene_names_uniprotkb": "Mkp3; CG14080; CG14081; DMKP-3; DMKP3; Dmel\\CG14080; Dmel_CG14080; Dmkp3; MKP3; dMKP3; mkp-3; mkp3", "gene_names_refseq": "CG14080; CG14081; DMKP-3; DMKP3; Dmel\\CG14080; Dmkp3; MKP3; Mkp3; dMKP3; mkp-3; mkp3", "protein_names_uniprotkb": "Dual specificity protein phosphatase Mpk3; 3.1.3.16; 3.1.3.48; DMKP3; Drosophila MKP3; MAP kinase phosphatase 3; MKP-3; Mitogen-activated protein kinase phosphatase 3", "protein_names_refseq": "CG14080-PD; ERK-inhibitory phosphatase; MAP kinase phosphatase 3; MAPK phosphatase 3; MAPK phosphatase-3; MKP-3-like; MKP-like; Mitogen-activated protein kinase phosphatase 3, isoform D; Mkp3-PD; drosophila MKP-3", "tax_id": 7227, "disease": "hypogonadotropic hypogonadism 19 with or without anosmia (Disease Ontology:DOID:0090090); breast cancer (Disease Ontology:DOID:1612); brain ischemia (Disease Ontology:DOID:2316); pancreatitis (Disease Ontology:DOID:4989)", "pathway": " (dme:Dmel_CG14080); (R-DME-112409); (R-DME-202670); (R-DME-5675221)", "pathway_count": 4, "publication_count": 18, "publication_id_list": "10731132;11742539;12537568;12537569;12537572;12537573;12537574;12810595;14701731;15033693;15704110;16110336;16831830;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "Negatively regulates the activity of members of the MAP kinase family in response to changes in the cellular environment. Has a specificity for the ERK family. Acts as a negative regulator in a variety of developmental processes including cell differentiation and proliferation controlled by the Ras/ERK pathway. Suppresses the photoreceptor cell differentiation and wing vein formation. Required for proper oogenesis and early embryogenesis. Functions autonomously in a subset of photoreceptor progenitor cells in eye imaginal disks. Also appears to be required in surrounding non-neuronal cells for ommatidial patterning and photoreceptor differentiation. Plays a role in the maintenance of epithelial integrity during tracheal development., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 3, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q86P14;Q95SV1;Q9VVW4", "ec_number_list": "3.1.3.16;3.1.3.48;3.1.3.-;2.7.11.24;3.1.3.2;3.1.3.27", "go_molecular_function": "GO:0004722 protein serine/threonine phosphatase activity;GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity;GO:0008330 protein tyrosine/threonine phosphatase activity;GO:0033550 MAP kinase tyrosine phosphatase activity;GO:0016301 kinase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0046627 negative regulation of insulin receptor signaling pathway;GO:0042127 regulation of cell population proliferation;GO:0070373 negative regulation of ERK1 and ERK2 cascade;GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway;GO:0002385 mucosal immune response", "synthesized_glycan_count": 0, "hit_score": 1.9, "record_id": "Q9VVW5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VP22-1", "uniprot_id": "CDK12_DROME", "mass": 128333.0, "length": 1157, "protein_name": "Cyclin-dependent kinase 12", "gene_name": "Cdk12", "organism": "Fruit fly", "refseq_name": "Cyclin-dependent kinase 12, isoform C", "refseq_ac": "NP_001262167", "gene_names_uniprotkb": "Cdk12; AC017581; CDK12; CG7597; Dmel\\CG7597; Dmel_CG7597; anon-WO0140519.165; cdk12; cg7597; dCDK12; dCdk12; gi24668141", "gene_names_refseq": "AC017581; CDK12; CG7597; Cdk12; Dmel\\CG7597; anon-WO0140519.165; cdk12; cg7597; dCDK12; dCdk12; gi24668141", "protein_names_uniprotkb": "Cyclin-dependent kinase 12; 2.7.11.22; 2.7.11.23; Cell division protein kinase 12; dCdk12", "protein_names_refseq": "CG7597-PC; Cdk12-PC; Cyclin-dependent kinase 12, isoform C", "tax_id": 7227, "disease": "congenital heart defects, dysmorphic facial features, and intellectual developmental disorder (Disease Ontology:DOID:0112247); prostate cancer (Disease Ontology:DOID:10283); prostate carcinoma (Disease Ontology:DOID:10286); stomach cancer (Disease Ontology:DOID:10534); intellectual disability (Disease Ontology:DOID:1059); breast cancer (Disease Ontology:DOID:1612); gastric adenocarcinoma (Disease Ontology:DOID:3717); hepatocellular carcinoma (Disease Ontology:DOID:684)", "pathway": " (dme:Dmel_CG7597); (R-DME-6796648); (R-DME-6798695)", "pathway_count": 3, "publication_count": 15, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17372656;17569856;17569867;18327897;20952539;25589440;26109356;26109357", "class_list": "", "function": "Cyclin-dependent kinase which displays CTD kinase activity: hyperphosphorylates the C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit, thereby acting as a key regulator of transcription elongation., [UniProtKB, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 19, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 8, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "Q8T9E1;Q95SE1", "ec_number_list": "2.7.11.17;2.7.11.1;2.7.11.13;2.4.1.186;2.7.11.24;5.4.2.7;5.4.2.-;3.2.1.31;1.1.1.42;2.7.11.22;2.4.2.1;2.7.11.23;2.7.1.40;2.7.11.21;2.7.7.6;4.1.2.13;2.7.4.6;5.6.1.8;2.7.11.11;3.6.5.-;1.11.1.6;2.7.12.1;5.3.1.9;2.7.1.11;2.7.11.25;5.6.2.4;2.7.11.12;1.1.1.205;3.4.22.-;3.6.4.12;2.7.12.2;3.6.4.6;1.16.3.1;5.6.2.3;2.3.2.5;3.4.24.-;2.3.2.27;2.7.10.2;2.7.1.1;5.2.1.8;3.4.19.-;1.11.1.24;5.6.1.5;5.4.2.11;5.4.2.4;3.2.1.23;3.6.1.5;3.6.4.13;3.3.2.6;3.5.4.5;4.2.1.24;5.4.2.2;2.7.11.39;3.4.-.-;3.1.3.16;2.4.1.25;3.2.1.33;2.7.1.-;3.5.4.6;2.3.2.26", "go_molecular_function": "GO:0005524 ATP binding;GO:0004693 cyclin-dependent protein serine/threonine kinase activity;GO:0008353 RNA polymerase II CTD heptapeptide repeat kinase activity;GO:0030332 cyclin binding;GO:0140311 protein sequestering activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0000228 nuclear chromosome;GO:0019908 nuclear cyclin-dependent protein kinase holoenzyme complex;GO:0008024 cyclin/CDK positive transcription elongation factor complex", "go_biological_process": "GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0006366 transcription by RNA polymerase II;GO:0032968 positive regulation of transcription elongation by RNA polymerase II;GO:0051214 RNAi-mediated antiviral immunity against RNA virus", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "Q9VP22-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9V410-1", "uniprot_id": "LZTR1_DROME", "mass": 106435.0, "length": 975, "protein_name": "Leucine-zipper-like transcriptional regulator 1 homolog", "gene_name": "Lztr1", "organism": "Fruit fly", "refseq_name": "leucine zipper like transcription regulator 1, isoform E", "refseq_ac": "NP_569869", "gene_names_uniprotkb": "Lztr1; CG3711; Dmel\\CG3711; Dmel_CG3711; EG:BACR7A4.19; LZTR1; night owl; nowl", "gene_names_refseq": "CG3711; Dmel\\CG3711; EG:BACR7A4.19; LZTR1; Lztr1; nowl", "protein_names_uniprotkb": "Leucine-zipper-like transcriptional regulator 1 homolog", "protein_names_refseq": "CG3711-PE; Lztr1-PE; leucine zipper like transcription regulator 1, isoform E; night owl", "tax_id": 7227, "disease": "Noonan syndrome 2 (Disease Ontology:DOID:0060580); Noonan syndrome 10 (Disease Ontology:DOID:0060588); schwannomatosis 2 (Disease Ontology:DOID:0070481); stomach cancer (Disease Ontology:DOID:10534); hypertrophic cardiomyopathy (Disease Ontology:DOID:11984); glioblastoma (Disease Ontology:DOID:3068); neurilemmoma (Disease Ontology:DOID:3192); schwannomatosis (Disease Ontology:DOID:3204); Noonan syndrome (Disease Ontology:DOID:3490); hepatocellular carcinoma (Disease Ontology:DOID:684)", "pathway": " (dme:Dmel_CG3711)", "pathway_count": 1, "publication_count": 15, "publication_id_list": "10731132;10731137;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357;30442766;32339168", "class_list": "", "function": "Inhibitor of Ras signaling (PubMed:30442766). Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates ubiquitination of Ras GTPases and Ras-like protein (By similarity). Together with Nf1, plays an important role for normal sleep behavior, mainly during the night (PubMed:32339168). Might affect sleep by modulating GABA signaling in Rdl-expressing neurons (PubMed:32339168). Might play a role in the regulation of brain glycogen metabolism and organismal levels of triglycerides (PubMed:32339168)., [UniProtKB, PubMed, PubMed, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 10, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0055038 recycling endosome membrane;GO:0031463 Cul3-RING ubiquitin ligase complex", "go_biological_process": "GO:0046580 negative regulation of Ras protein signal transduction;GO:0007214 gamma-aminobutyric acid signaling pathway;GO:0016567 protein ubiquitination;GO:0030431 sleep;GO:0070328 triglyceride homeostasis", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "Q9V410-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9W0M2-1", "uniprot_id": "GR61A_DROME", "mass": 49920.0, "length": 436, "protein_name": "Gustatory receptor for sugar taste 61a", "gene_name": "Gr61a", "organism": "Fruit fly", "refseq_name": "gustatory receptor 61a, isoform B", "refseq_ac": "NP_001261226", "gene_names_uniprotkb": "Gr61a; CG13888; Dmel61a; Dmel\\CG13888; Dmel_CG13888; GR61a; Gr61D1", "gene_names_refseq": "CG13888; Dmel61a; Dmel\\CG13888; GR61a; Gr61D1; Gr61a", "protein_names_uniprotkb": "Gustatory receptor for sugar taste 61a", "protein_names_refseq": "CG13888-PB; Gr61a-PB; gustatory receptor 61D1; gustatory receptor 61a, isoform B", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG13888)", "pathway_count": 1, "publication_count": 16, "publication_id_list": "10731132;11516643;12537568;12537572;12537573;12537574;14608037;16110336;17569856;17569867;17715294;23418550;23850280;25589440;26109356;26109357", "class_list": "", "function": "One of the few identified sugar gustatory receptors identified so far with glucose being its primary ligand and which mediates acceptance behavior., [UniProtKB, PubMed, PubMed, PubMed]; Plays a role in the sugar gustatory response., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0015276 ligand-gated monoatomic ion channel activity;GO:0033041 sweet taste receptor activity;GO:0008527 taste receptor activity;GO:0170023 ionotropic sweet taste receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane", "go_biological_process": "GO:0007165 signal transduction;GO:0034220 monoatomic ion transmembrane transport;GO:0050909 sensory perception of taste;GO:0050916 sensory perception of sweet taste", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "Q9W0M2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VZE7-1", "uniprot_id": "CTL1L_DROME", "mass": 76840.0, "length": 691, "protein_name": "Choline transporter-like 1", "gene_name": "Ctl1", "organism": "Fruit fly", "refseq_name": "choline transporter-like 1, isoform A", "refseq_ac": "NP_647884", "gene_names_uniprotkb": "Ctl1; CG1311; DmCTL1; Dmel\\CG1311; Dmel_CG1311", "gene_names_refseq": "CG1311; Ctl1; DmCTL1; Dmel\\CG1311", "protein_names_uniprotkb": "Choline transporter-like 1", "protein_names_refseq": "CG1311-PA; Ctl1-PA; choline transporter-like 1, isoform A", "tax_id": 7227, "disease": "high grade glioma (Disease Ontology:DOID:3070)", "pathway": " (dme:Dmel_CG1311); (R-DME-1483191); (R-DME-6798163); (R-DME-9958517)", "pathway_count": 4, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "Choline transporter., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "Q86P33", "ec_number_list": "", "go_molecular_function": "GO:0022857 transmembrane transporter activity", "go_cellular_component": "GO:0016020 membrane;GO:0005886 plasma membrane", "go_biological_process": "GO:0055085 transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VZE7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VUF8-1", "uniprot_id": "CP314_DROME", "mass": 61690.0, "length": 540, "protein_name": "Ecdysone 20-monooxygenase", "gene_name": "shd", "organism": "Fruit fly", "refseq_name": "shade, isoform D", "refseq_ac": "NP_001261843", "gene_names_uniprotkb": "shd; 314a1; CG13478; CYP314A1; Cyp314a1; Dmel\\CG13478; Dmel_CG13478; Shade; Shd; cyp314a1", "gene_names_refseq": "314a1; CG13478; CYP314A1; Cyp314a1; Dmel\\CG13478; Shade; Shd; cyp314a1; shd", "protein_names_uniprotkb": "Ecdysone 20-monooxygenase; 1.14.99.22; CYPCCCXIVA1; Cytochrome P450 314a1, mitochondrial; E20MO; Protein shade", "protein_names_refseq": "CG13478-PD; cytochrome P450; ecdysone 20-monooxygenase; shade, isoform D; shade; shd-PD", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG13478)", "pathway_count": 1, "publication_count": 14, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;12676319;14610274;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "Required for CNS development; midline glial cells. Involved in the metabolism of insect hormones; responsible for all ecdysone 20-monooxygenase activity during embryonic, larval and adult stages. May be involved in the breakdown of synthetic insecticides., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q8T483", "ec_number_list": "1.14.-.-;1.14.99.22", "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0004501 ecdysone 20-monooxygenase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0031966 mitochondrial membrane;GO:0016020 membrane", "go_biological_process": "GO:0007417 central nervous system development;GO:0007494 midgut development;GO:0035074 pupation;GO:0045456 ecdysteroid biosynthetic process;GO:0007295 growth of a germarium-derived egg chamber", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "Q9VUF8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VVN6-1", "uniprot_id": "CP312_DROME", "mass": 58805.0, "length": 510, "protein_name": "Probable cytochrome P450 312a1", "gene_name": "Cyp312a1", "organism": "Fruit fly", "refseq_name": "cytochrome P450 312a1, isoform B", "refseq_ac": "NP_001262008", "gene_names_uniprotkb": "Cyp312a1; 312a1; CG5137; Dmel\\CG5137; Dmel_CG5137; P450 IV", "gene_names_refseq": "312a1; CG5137; Cyp312a1; Dmel\\CG5137; P450 IV", "protein_names_uniprotkb": "Probable cytochrome P450 312a1; 1.14.-.-; CYPCCCXIIA1", "protein_names_refseq": "CG5137-PB; Cyp312a1-PB; cytochrome P450 312a1, isoform B; cytochrome P450", "tax_id": 7227, "disease": "aromatase excess syndrome (Disease Ontology:DOID:0090122); prostate cancer (Disease Ontology:DOID:10283); Alzheimer's disease (Disease Ontology:DOID:10652); hypertension (Disease Ontology:DOID:10763); osteoporosis (Disease Ontology:DOID:11476); polycystic ovary syndrome (Disease Ontology:DOID:11612); protein-energy malnutrition (Disease Ontology:DOID:11801); urethral obstruction (Disease Ontology:DOID:12577); Sjogren's syndrome (Disease Ontology:DOID:12894); endometrial cancer (Disease Ontology:DOID:1380); bladder neck obstruction (Disease Ontology:DOID:13948); hypothyroidism (Disease Ontology:DOID:1459); prostatitis (Disease Ontology:DOID:14654); breast cancer (Disease Ontology:DOID:1612); disorder of sexual development (Disease Ontology:DOID:1923); ovarian cancer (Disease Ontology:DOID:2394); endometriosis (Disease Ontology:DOID:289); placental insufficiency (Disease Ontology:DOID:3891); esophagus adenocarcinoma (Disease Ontology:DOID:4914); prostate carcinoma in situ (Disease Ontology:DOID:8634)", "pathway": " (dme:Dmel_CG5137); (R-DME-193144); (R-DME-196791); (R-DME-211916); (R-DME-211976)", "pathway_count": 5, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 20, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q1ECB7", "ec_number_list": "1.14.-.-;1.14.15.-", "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0004497 monooxygenase activity;GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VVN6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VQ30-1", "uniprot_id": "CHNMO_DROME", "mass": 62230.0, "length": 604, "protein_name": "Zinc finger protein chinmo", "gene_name": "chinmo", "organism": "Fruit fly", "refseq_name": "chronologically inappropriate morphogenesis, isoform H", "refseq_ac": "NP_001245839", "gene_names_uniprotkb": "chinmo; CG10871; CG17156; CG17649; CG31666; Chinmo; Dmel\\CG31666; Dmel_CG31666; F; l(2)04111", "gene_names_refseq": "CG10871; CG17156; CG17649; CG31666; Chinmo; Dmel\\CG31666; F; chinmo; l(2)04111", "protein_names_uniprotkb": "Zinc finger protein chinmo; Protein chronologically inappropriate morphogenesis", "protein_names_refseq": "CG31666-PH; chinmo-PH; chronologically -inappropriate morphogenesis; chronologically inappropriate morphogenesis, isoform H; chronologically inappropriate morphogenesis; lethal (2) 04111", "tax_id": 7227, "disease": "brain cancer (Disease Ontology:DOID:1319)", "pathway": " (dme:Dmel_CG31666)", "pathway_count": 1, "publication_count": 18, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17055440;17569856;17569867;20412771;25453558;25589440;26021350;26109356;26109357;26811385;29389999", "class_list": "", "function": "Required for morphological differentiation of postmitotic neurons during postembryonic brain development (PubMed:17055440). Ensures production of appropriate neuron subtypes within a lineage by preventing precocious generation of late neuronal types of that lineage (PubMed:17055440). Acts as a downstream mediator of the transcriptional activator Stat92e and is required for the development of the eye-antennal disk which gives rise to the adult eye, antenna and head capsule, for transcriptional repression of the Notch receptor ligand Ser and for the self-renewal of cyst stem cells in the testis (PubMed:20412771). In the adult testis, maintains the male identify of adult somatic cyst stem cells (PubMed:25453558, PubMed:29389999). Represses expression and alternative splicing of transformer pre-mRNA, resulting in the production of the male-specific isoform of transcription factor dsx which ensures male-specific transcription of target genes (PubMed:25453558, PubMed:29389999). Plays a role in actin nuclear localization through its involvement in repressing the expression of the kinase Cdi (PubMed:26021350). This maintains the cofilin/actin-depolymerizing factor homolog tsr in its unphosphorylated state which is required for actin nuclear import (PubMed:26021350)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q8IGM8;Q9VQ31", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0007548 sex differentiation;GO:0019102 male somatic sex determination;GO:0048666 neuron development;GO:0061771 response to caloric restriction", "synthesized_glycan_count": 0, "hit_score": 1.9, "record_id": "Q9VQ30-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VLL3-1", "uniprot_id": "AK200_DROME", "mass": 79029.0, "length": 753, "protein_name": "A-kinase anchor protein 200", "gene_name": "Akap200", "organism": "Fruit fly", "refseq_name": "A kinase anchor protein 200, isoform E", "refseq_ac": "NP_001285751", "gene_names_uniprotkb": "Akap200; AKAP200; Akap 200; BcDNA:LP02734; CG13388; DAKAP200; Dmel\\CG13388; Dmel_CG13388; EP(2)2254; MESR2; akap200; anon-WO0118547.134; anon-WO0118547.213; dpo", "gene_names_refseq": "AKAP200; Akap 200; Akap200; BcDNA:LP02734; CG13388; DAKAP200; Dmel\\CG13388; EP(2)2254; MESR2; akap200; anon-WO0118547.134; anon-WO0118547.213; dpo", "protein_names_uniprotkb": "A-kinase anchor protein 200", "protein_names_refseq": "A kinase anchor protein 200, isoform E; A kinase anchor protein; Akap200-PE; CG13388-PE", "tax_id": 7227, "disease": "alcohol use disorder (Disease Ontology:DOID:1574)", "pathway": " (dme:Dmel_CG13388)", "pathway_count": 1, "publication_count": 17, "publication_id_list": "10480936;10480937;10731132;12223401;12537568;12537572;12537573;12537574;16110336;17569856;17569867;23929551;25589440;26109356;26109357;29309414;29444420", "class_list": "", "function": "Scaffolding protein involved in the regulation of PKA signaling and anchoring to the actin cytoskeleton integrating signals propagated by cAMP, diacylglycerol and calcium (PubMed:10480936, PubMed:10480937, PubMed:12223401). Contributes to the maintenance and regulation of cytoskeletal structures in germline via PKA-mediated signaling (PubMed:12223401). As part of ethanol response in the glia, mediates ethanol-induced structural remodeling of actin cytoskeleton and perineurial membrane topology by anchoring PKA to the membrane of perineurial glia (PubMed:29444420). In specific tissues such as eye and thorax, promotes N/Notch protein stability by inhibiting Cbl-mediated ubiquitination and lysosomal degradation pathway of N/Notch in a PKA-independent way (PubMed:29309414). In the circadian brain neurons evening cells (E-cells), might have a role in circadian pacemaker synchronization by playing a redundant role in signaling downstream of the G protein-couple receptor Pdfr (PubMed:23929551)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 10, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "Q8IPF5;Q9U7E7", "ec_number_list": "", "go_molecular_function": "GO:0051015 actin filament binding;GO:0005112 Notch binding;GO:0034237 protein kinase A regulatory subunit binding;GO:0016301 kinase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005856 cytoskeleton;GO:0005886 plasma membrane", "go_biological_process": "GO:0032956 regulation of actin cytoskeleton organization;GO:0048149 behavioral response to ethanol;GO:0045747 positive regulation of Notch signaling pathway;GO:0071361 cellular response to ethanol;GO:0007623 circadian rhythm", "synthesized_glycan_count": 0, "hit_score": 1.8, "record_id": "Q9VLL3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9V3S0-1", "uniprot_id": "CP4G1_DROME", "mass": 62971.0, "length": 556, "protein_name": "Cytochrome P450 4g1", "gene_name": "Cyp4g1", "organism": "Fruit fly", "refseq_name": "cytochrome P450 4g1", "refseq_ac": "NP_525031", "gene_names_uniprotkb": "Cyp4g1; CG3972", "gene_names_refseq": "4g1; ASC-T1; CG3972; CYP4G1; Cyp4G1; Cyp4g1; Cyt-P450-A1; Dmel\\CG3972; EG:165H7.1; P-450-A; P-450; P450-A; P450A; P450; T1; anon-WO0140519.102; cyp4g1; scgamma", "protein_names_uniprotkb": "Cytochrome P450 4g1; 1.14.-.-; Cytochrome P450 hydroxylase; P450hyd", "protein_names_refseq": "Achaete-scute complex transcript 1; CG3972-PA; Cyp4g1-PA; cytochrome P450 4g1; cytochrome P450 A1; cytochrome P450-4g1", "tax_id": 7227, "disease": "Bietti crystalline corneoretinal dystrophy (Disease Ontology:DOID:0050664); hypertension (Disease Ontology:DOID:10763); polycystic ovary syndrome (Disease Ontology:DOID:11612); protein-energy malnutrition (Disease Ontology:DOID:11801); hypothyroidism (Disease Ontology:DOID:1459); endometriosis (Disease Ontology:DOID:289); placental insufficiency (Disease Ontology:DOID:3891)", "pathway": " (dme:Dmel_CG3972); (R-DME-193144); (R-DME-196791); (R-DME-211916); (R-DME-211976)", "pathway_count": 5, "publication_count": 7, "publication_id_list": "10731132;10731137;12537569;12537572;22927409;38008364;8676871", "class_list": "", "function": "Oxidative decarbonylase catalyzing the terminal step in insect hydrocarbon production (PubMed:22927409). Together with Cpr involved in production of cuticular hydrocarbons used for waterproofing and chemical communication (PubMed:22927409). May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 7, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A9UN25;Q24126;Q95U60", "ec_number_list": "1.14.-.-;1.14.15.-", "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0004497 monooxygenase activity;GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0160238 long-chain fatty aldehyde oxidative decarbonylase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006723 cuticle hydrocarbon biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q9V3S0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9V3S9-1", "uniprot_id": "BGM_DROME", "mass": 73611.0, "length": 666, "protein_name": "Very long-chain-fatty-acid--CoA ligase bubblegum", "gene_name": "bgm", "organism": "Fruit fly", "refseq_name": "bubblegum, isoform C", "refseq_ac": "NP_001285923", "gene_names_uniprotkb": "bgm; CG4501", "gene_names_refseq": "2a9hom; BG:DS01514.2; BG:DS0514.2; Bgm; CG4501; Dmel\\CG4501; bgm", "protein_names_uniprotkb": "Very long-chain-fatty-acid--CoA ligase bubblegum; 6.2.1.3", "protein_names_refseq": "CG4501-PC; bgm-PC; bubblegum, isoform C; bubblegum", "tax_id": 7227, "disease": "adrenoleukodystrophy (Disease Ontology:DOID:10588)", "pathway": " (dme:Dmel_CG4501); (R-DME-75876)", "pathway_count": 2, "publication_count": 7, "publication_id_list": "10373116;10731132;12537569;12537572;25409104;26893370;29739804", "class_list": "", "function": "Mediates activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation (PubMed:10373116, PubMed:26893370, PubMed:29739804). Probably by regulating lipid storage and catabolism, plays a role in neuronal function (PubMed:25409104)., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q8MT84", "ec_number_list": "6.2.1.3", "go_molecular_function": "GO:0005524 ATP binding;GO:0004467 long-chain fatty acid-CoA ligase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0001676 long-chain fatty acid metabolic process;GO:0006631 fatty acid metabolic process;GO:0070050 neuron cellular homeostasis;GO:0045938 positive regulation of circadian sleep/wake cycle, sleep;GO:0034976 response to endoplasmic reticulum stress", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q9V3S9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9V3T9-1", "uniprot_id": "ADRO_DROME", "mass": 51353.0, "length": 466, "protein_name": "NADPH:adrenodoxin oxidoreductase, mitochondrial", "gene_name": "dare", "organism": "Fruit fly", "refseq_name": "defective in the avoidance of repellents", "refseq_ac": "NP_477150", "gene_names_uniprotkb": "dare; CG12390", "gene_names_refseq": "AR; CG12390; Dare; Dmel\\CG12390; W8; dare", "protein_names_uniprotkb": "NADPH:adrenodoxin oxidoreductase, mitochondrial; 1.18.1.6; AR; Adrenodoxin reductase; Ferredoxin reductase; Ferredoxin--NADP(+) reductase", "protein_names_refseq": "ADXRDTASE; CG12390-PA; adrenodoxin reductase; dare-PA; defective in the avoidance of repellents", "tax_id": 7227, "disease": "retinitis pigmentosa (Disease Ontology:DOID:10584); Parkinson's disease (Disease Ontology:DOID:14330); auditory system disease (Disease Ontology:DOID:2742); optic atrophy (Disease Ontology:DOID:5723)", "pathway": " (dme:Dmel_CG12390); (R-DME-2395516)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "10498693;10731132;12537572", "class_list": "", "function": "Required for synthesis of steroid hormones, for olfactory sensory behavior and completion of the second larval molt (a steroid mediated developmental transition) and pupariation., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.18.1.6", "go_molecular_function": "GO:0004324 ferredoxin-NADP+ reductase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane;GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0016226 iron-sulfur cluster assembly;GO:0008203 cholesterol metabolic process;GO:0006694 steroid biosynthetic process;GO:0006744 ubiquinone biosynthetic process;GO:0007552 metamorphosis", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9V3T9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9V3Y2-1", "uniprot_id": "DRE2_DROME", "mass": 27105.0, "length": 248, "protein_name": "Anamorsin homolog", "gene_name": "CIAPIN1", "organism": "Fruit fly", "refseq_name": "cytokine induced apoptosis inhibitor 1", "refseq_ac": "NP_524938", "gene_names_uniprotkb": "CIAPIN1; CG4180; l(2)35Bg", "gene_names_refseq": "BG:DS00929.9; B; CG4180; CIAPIN1; D-CIAPIN1; D1; Dmel\\CG4180; anon-35Ba; br26; l(2)35Bg; l(2)br26", "protein_names_uniprotkb": "Anamorsin homolog; Fe-S cluster assembly protein DRE2 homolog", "protein_names_refseq": "CG4180-PA; CIAPIN1 ortholog; CIAPIN1-PA; cytokine induced apoptosis inhibitor 1; lethal (2) 35Bg; lethal 26 in the black-reduced region; lethal group D1; transcription unit B", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG4180)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "10731132;12537569;12537572", "class_list": "", "function": "Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the cytosolic Fe-S scaffold complex. Electrons are transferred from NADPH via a FAD- and FMN-containing diflavin oxidoreductase. Together with the diflavin oxidoreductase, also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0009055 electron transfer activity;GO:0046872 metal ion binding;GO:0051539 4 iron, 4 sulfur cluster binding;GO:0051537 2 iron, 2 sulfur cluster binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005758 mitochondrial intermembrane space;GO:0005829 cytosol", "go_biological_process": "GO:0016226 iron-sulfur cluster assembly;GO:0043066 negative regulation of apoptotic process;GO:0044572 [4Fe-4S] cluster assembly", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9V3Y2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9V3Y3-1", "uniprot_id": "DFP_DROME", "mass": 17249.0, "length": 159, "protein_name": "Defense protein l(2)34Fc", "gene_name": "l(2)34Fc", "organism": "Fruit fly", "refseq_name": "lethal (2) 34Fc, isoform B", "refseq_ac": "NP_001285930", "gene_names_uniprotkb": "l(2)34Fc; A2; BG:DS01068.5; BcDNA:RE60882; CG7532; DS01068.5; Dmel\\CG7532; Dmel_CG7532; anon-EST:ParkEST060; br8; l(2)br8; l34Fc", "gene_names_refseq": "A2; BG:DS01068.5; BcDNA:RE60882; CG7532; DS01068.5; Dmel\\CG7532; anon-EST:ParkEST060; br8; l(2)34Fc; l(2)br8; l34Fc", "protein_names_uniprotkb": "Defense protein l(2)34Fc", "protein_names_refseq": "CG7532-PB; l(2)34Fc-PB; lethal (2) 34Fc, isoform B; lethal 8 in the black-reduced region; lethal group A2", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG7532)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "10731132;12032070;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "May have antimicrobial activity. A late response immune regulated gene that is negatively regulated by spz during the immune response., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005576 extracellular region;GO:0016020 membrane", "go_biological_process": "GO:0045087 innate immune response;GO:0042742 defense response to bacterium;GO:0050777 negative regulation of immune response;GO:0042832 defense response to protozoan", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "Q9V3Y3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9V3Z6-1", "uniprot_id": "MYO7A_DROME", "mass": 250309.0, "length": 2167, "protein_name": "Myosin-VIIa", "gene_name": "ck", "organism": "Fruit fly", "refseq_name": "crinkled, isoform C", "refseq_ac": "NP_001285949", "gene_names_uniprotkb": "ck; CG7595", "gene_names_refseq": "53D10S; BG:DS00929.11; CG7595; CK; D2; DM7a; DMyoVIIa; Dm 35B; DmVIIA; DmVIIa; Dmel\\CG7595; Dro35B; D; ESTS:53D10S; Mhc35BC; Myo7A; Myo7B; MyoVIIA; anon-35Bb; br27; ck/MyoVIIA; ck; l(1)35Ca; l(2)07130; l(2)35Ca; l(2)br27; l35Ca; myoVIIA; myoVIIa; myosin-7a; stch; stc", "protein_names_uniprotkb": "Myosin-VIIa; DmVIIa; Protein crinkled", "protein_names_refseq": "CG7595-PC; ck-PC; crinkled, isoform C; crinkled; lethal 27 in the black-reduced region; lethal group D2; myosin 7a heavy chain; myosin 7a; myosin VIIa; myosin VII; myosin heavy chain at 35BC; myosin-7a; myosin-VII; mysoin VIIa; stubby chaetae; transcription unit D", "tax_id": 7227, "disease": "Usher syndrome type 1B (Disease Ontology:DOID:0070655); autosomal recessive nonsyndromic deafness 2 (Disease Ontology:DOID:0110477); autosomal dominant nonsyndromic deafness 11 (Disease Ontology:DOID:0110543); Usher syndrome type 1 (Disease Ontology:DOID:0110826); sensorineural hearing loss (Disease Ontology:DOID:10003); Leber congenital amaurosis (Disease Ontology:DOID:14791); auditory system disease (Disease Ontology:DOID:2742); congenital nystagmus (Disease Ontology:DOID:9649)", "pathway": " (dme:Dmel_CG7595); (R-DME-2453902)", "pathway_count": 2, "publication_count": 8, "publication_id_list": "10731132;12537572;15579689;15886106;16585515;18327897;25236597;27331610", "class_list": "", "function": "Myosins are actin-based motor molecules with ATPase activity (PubMed:16585515). Unconventional myosins serve in intracellular movements: can function in cells as a single-molecule cargo transporter (PubMed:16585515). A very slow and high-duty-ratio motor, may be suitable for tension maintenance of actin filaments (PubMed:16585515). Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments (PubMed:15579689). Plays a key role in the formation of cellular projections and other actin-based functions required for embryonic and larval viability (PubMed:15579689, PubMed:16585515). Necessary for auditory transduction: plays a role in Johnston's organ organization by functioning in scolopidial apical attachment and therefore to acoustic stimulus propagation from the antenna a2/a3 joint to transducing elements (PubMed:15886106, PubMed:27331610). Interaction with the myosin zip may be important for its function in scolopidial apical attachment (PubMed:27331610). During oogenesis it has Cad99c-dependent and Cad99c-independent roles in regulating the shape and spacing of the follicle cell microvilli which secrete eggshell material such as the vitelline membrane (PubMed:25236597). May be required for the normal expression of Cad99c in the follicle cell microvilli (PubMed:25236597)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 8, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q6NNF6;Q8T0A9", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0051015 actin filament binding;GO:0045296 cadherin binding;GO:0032027 myosin light chain binding;GO:0000146 microfilament motor activity", "go_cellular_component": "GO:0045180 basal cortex;GO:0045179 apical cortex;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005938 cell cortex", "go_biological_process": "GO:0006897 endocytosis;GO:0007015 actin filament organization;GO:0046847 filopodium assembly;GO:0030048 actin filament-based movement;GO:0007605 sensory perception of sound", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q9V3Z6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9V419-1", "uniprot_id": "C28A5_DROME", "mass": 57705.0, "length": 505, "protein_name": "Probable cytochrome P450 28a5", "gene_name": "Cyp28a5", "organism": "Fruit fly", "refseq_name": "cytochrome P450 28a5", "refseq_ac": "NP_609694", "gene_names_uniprotkb": "Cyp28a5; CG8864", "gene_names_refseq": "28a5; BEST:GH10483; BG:DS00180.11; CG8864; CYP28A5; CYP28a5; Cyp28A5; Cyp28a5; DS00180.11; Dmel\\CG8864; cyp28a5; gh10483", "protein_names_uniprotkb": "Probable cytochrome P450 28a5; 1.14.-.-; CYPXXVIIIA5", "protein_names_refseq": "CG8864-PA; Cyp28a5-PA; cytochrome P450 28a5; cytochrome P450", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG8864)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "10471707;10731132;12537569;12537572", "class_list": "", "function": "May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0004497 monooxygenase activity;GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q9V419-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9V431-1", "uniprot_id": "API5_DROME", "mass": 59930.0, "length": 536, "protein_name": "Apoptosis inhibitor 5 homolog", "gene_name": "cass", "organism": "Fruit fly", "refseq_name": "cassowary", "refseq_ac": "NP_477454", "gene_names_uniprotkb": "cass; Aac11; CG6582", "gene_names_refseq": "AAC-11; Aac11; Api5; BcDNA.LD09852; BcDNA:LD09852; CG6582; Dmel\\CG6582; bad; cass; cas; l(2)k06710", "protein_names_uniprotkb": "Apoptosis inhibitor 5 homolog; AAC-11; API-5; Antiapoptosis clone 11 protein homolog; Protein cassowary", "protein_names_refseq": "Aac11; CG6582-PA; antiapoptosis clone 11; antiapoptosis clone-11; apoptosis inhibitor-5; bladderwrack; cass-PA; cassowary", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG6582)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "10731132;12537572;17112319", "class_list": "", "function": "Antiapoptotic factor. Also known to efficiently suppress E2F1-induced apoptosis., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0043066 negative regulation of apoptotic process;GO:0006915 apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9V431-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9V4I0-1", "uniprot_id": "CP9B1_DROME", "mass": 58736.0, "length": 505, "protein_name": "Cytochrome P450 9b1", "gene_name": "Cyp9b1", "organism": "Fruit fly", "refseq_name": "cytochrome P450 9b1", "refseq_ac": "NP_523645", "gene_names_uniprotkb": "Cyp9b1; CG4485", "gene_names_refseq": "9b1; CG4485; CYP9B1; Cyp9b1; Dmel\\CG4485; P-450; P450", "protein_names_uniprotkb": "Cytochrome P450 9b1; 1.14.-.-; CYPIXB1", "protein_names_refseq": "CG4485-PA; Cyp9b1-PA; cytochrome P450 9b1; cytochrome P450-9b1", "tax_id": 7227, "disease": "alcohol dependence (Disease Ontology:DOID:0050741); thrombosis (Disease Ontology:DOID:0060903); alcohol-associated liver disease (Disease Ontology:DOID:0070658); B-lymphoblastic leukemia/lymphoma (Disease Ontology:DOID:0080630); acute necrotizing pancreatitis (Disease Ontology:DOID:0080998); prostate cancer (Disease Ontology:DOID:10283); Alzheimer's disease (Disease Ontology:DOID:10652); hypertension (Disease Ontology:DOID:10763); essential hypertension (Disease Ontology:DOID:10825); membranous glomerulonephritis (Disease Ontology:DOID:10976); hydronephrosis (Disease Ontology:DOID:11111); cholestasis (Disease Ontology:DOID:13580); depressive disorder (Disease Ontology:DOID:1596); anxiety disorder (Disease Ontology:DOID:2030); arteriosclerosis (Disease Ontology:DOID:2349); glomerulonephritis (Disease Ontology:DOID:2921); familial Mediterranean fever (Disease Ontology:DOID:2987); brain infarction (Disease Ontology:DOID:3454); liver cirrhosis (Disease Ontology:DOID:5082); oral submucous fibrosis (Disease Ontology:DOID:5773); end stage renal disease (Disease Ontology:DOID:783); chronic myeloid leukemia (Disease Ontology:DOID:8552); pulmonary embolism (Disease Ontology:DOID:9477); acute lymphoblastic leukemia (Disease Ontology:DOID:9952)", "pathway": " (dme:Dmel_CG4485)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "10731132;12537572;8676871", "class_list": "", "function": "May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 24, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q24122", "ec_number_list": "", "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0004497 monooxygenase activity;GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9V4I0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9V4I1-1", "uniprot_id": "CP9B2_DROME", "mass": 58911.0, "length": 505, "protein_name": "Cytochrome P450 9b2", "gene_name": "Cyp9b2", "organism": "Fruit fly", "refseq_name": "cytochrome P450 9b2", "refseq_ac": "NP_523646", "gene_names_uniprotkb": "Cyp9b2; CG4486", "gene_names_refseq": "9b2; BEST:GH08116; CG4486; CYP9B2; Cyp9B2; Cyp9b2; Dmel\\CG4486; P-450 Cyp9b2; P-450; P450; cyp9b2", "protein_names_uniprotkb": "Cytochrome P450 9b2; 1.14.-.-; CYPIXB2", "protein_names_refseq": "CG4486-PA; Cyp9b2-PA; cytochrome P450 9b2; cytochrome P450-9b2; cytochrome P450; fly plexin a", "tax_id": 7227, "disease": "alcohol dependence (Disease Ontology:DOID:0050741); thrombosis (Disease Ontology:DOID:0060903); alcohol-associated liver disease (Disease Ontology:DOID:0070658); B-lymphoblastic leukemia/lymphoma (Disease Ontology:DOID:0080630); acute necrotizing pancreatitis (Disease Ontology:DOID:0080998); prostate cancer (Disease Ontology:DOID:10283); Alzheimer's disease (Disease Ontology:DOID:10652); hypertension (Disease Ontology:DOID:10763); essential hypertension (Disease Ontology:DOID:10825); membranous glomerulonephritis (Disease Ontology:DOID:10976); hydronephrosis (Disease Ontology:DOID:11111); cholestasis (Disease Ontology:DOID:13580); depressive disorder (Disease Ontology:DOID:1596); anxiety disorder (Disease Ontology:DOID:2030); arteriosclerosis (Disease Ontology:DOID:2349); glomerulonephritis (Disease Ontology:DOID:2921); familial Mediterranean fever (Disease Ontology:DOID:2987); brain infarction (Disease Ontology:DOID:3454); liver cirrhosis (Disease Ontology:DOID:5082); oral submucous fibrosis (Disease Ontology:DOID:5773); end stage renal disease (Disease Ontology:DOID:783); chronic myeloid leukemia (Disease Ontology:DOID:8552); pulmonary embolism (Disease Ontology:DOID:9477); acute lymphoblastic leukemia (Disease Ontology:DOID:9952)", "pathway": " (dme:Dmel_CG4486)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "10731132;12537569;12537572;8676871", "class_list": "", "function": "May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 24, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q24123", "ec_number_list": "", "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0004497 monooxygenase activity;GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q9V4I1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9V4N3-1", "uniprot_id": "CYB5_DROME", "mass": 15206.0, "length": 134, "protein_name": "Cytochrome b5", "gene_name": "Cyt-b5", "organism": "Fruit fly", "refseq_name": "cytochrome b5, isoform B", "refseq_ac": "NP_610294", "gene_names_uniprotkb": "Cyt-b5; CG2140", "gene_names_refseq": "1857; BcDNA:GH02503; BcDNA:RE66521; CG2140; CYT-B5; CYTB5; Cyt-b5; Dmel\\CG2140; dpld; l(2)01857; l(2)k00107", "protein_names_uniprotkb": "Cytochrome b5; CYTB5", "protein_names_refseq": "CG2140-PB; Cyt-b5-PB; cytochrome b5, isoform B; dappled; lethal (2) k00107", "tax_id": 7227, "disease": "methemoglobinemia and ambiguous genitalia (Disease Ontology:DOID:0112316); methemoglobinemia (Disease Ontology:DOID:10783); pyelonephritis (Disease Ontology:DOID:11400); stomatitis (Disease Ontology:DOID:9637)", "pathway": " (dme:Dmel_CG2140); (R-DME-196836); (R-DME-9609523)", "pathway_count": 3, "publication_count": 3, "publication_id_list": "10731132;12537569;12537572", "class_list": "", "function": "Cytochrome b5 is a membrane-bound hemoprotein which functions as an electron carrier for several membrane-bound oxygenases., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q6AWQ2;Q8IH75;Q9I7E0", "ec_number_list": "", "go_molecular_function": "GO:0046872 metal ion binding;GO:0020037 heme binding", "go_cellular_component": "GO:0016020 membrane;GO:0005789 endoplasmic reticulum membrane;GO:0012505 endomembrane system", "go_biological_process": "GO:0006979 response to oxidative stress;GO:0006805 xenobiotic metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9V4N3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9V4P1-1", "uniprot_id": "ANLN_DROME", "mass": 136033.0, "length": 1239, "protein_name": "Anillin", "gene_name": "scra", "organism": "Fruit fly", "refseq_name": "scraps, isoform B", "refseq_ac": "NP_724582", "gene_names_uniprotkb": "scra; CG2092; ani", "gene_names_refseq": "ABP8; Abp8; Anillin; Anil; Ani; CG2092; Dmel\\CG2092; Scra; anillin; anil; ani; l(2)03427; l(2)43Ec; l(2)k08255; scra", "protein_names_uniprotkb": "Anillin; ABP8; Actin-binding protein 8; Protein scraps", "protein_names_refseq": "Actin-binding protein 8; CG2092-PB; anillin; annilin; lethal (2) k08255; scra-PB; scraps, isoform B; scraps", "tax_id": 7227, "disease": "focal segmental glomerulosclerosis 8 (Disease Ontology:DOID:0111133)", "pathway": " (dme:Dmel_CG2092); (R-DME-8980692)", "pathway_count": 2, "publication_count": 22, "publication_id_list": "10381388;10444383;10731132;10751177;12134082;12537569;12537572;12538517;14736750;15004238;15240570;15371536;15380073;15496454;15930114;16280552;18327897;20237161;7559773;9013326;9477328;9655801", "class_list": "", "function": "Required for cytokinesis. Essential for the structural integrity of the cleavage furrow and for completion of cleavage furrow ingression and proper formation of the midbody. Required during cellularization of syncytial embryos for the proper formation and function of the furrow canals, the stable inward folds of the plasma membrane which separate the peripheral nuclei. Also required for the formation of the pole cells, the progenitors of the adult germline which are formed by cytokinesis of the cytoplasmic buds at the posterior pole of the syncytial embryo. Essential for embryonic viability., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 5, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q24240;Q8MKN2;Q8T067", "ec_number_list": "", "go_molecular_function": "GO:0003779 actin binding;GO:0008017 microtubule binding;GO:0051015 actin filament binding;GO:0017022 myosin binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0031514 motile cilium;GO:0032154 cleavage furrow;GO:0005826 actomyosin contractile ring", "go_biological_process": "GO:0043063 intercellular bridge organization;GO:0007009 plasma membrane organization;GO:0000281 mitotic cytokinesis;GO:0008104 intracellular protein localization;GO:0042060 wound healing", "synthesized_glycan_count": 0, "hit_score": 2.3, "record_id": "Q9V4P1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9V4S8-1", "uniprot_id": "CSN7_DROME", "mass": 31068.0, "length": 278, "protein_name": "COP9 signalosome complex subunit 7", "gene_name": "CSN7", "organism": "Fruit fly", "refseq_name": "COP9 signalosome subunit 7", "refseq_ac": "NP_610379", "gene_names_uniprotkb": "CSN7; CG2038", "gene_names_refseq": "CG2038; CH7; CSN7b; CSN7; Csn7; Dch7; Dmel\\CG2038; csn7", "protein_names_uniprotkb": "COP9 signalosome complex subunit 7; Dch7; Signalosome subunit 7", "protein_names_refseq": "CG2038-PA; COP9 complex homolog subunit 7; COP9 signalosome subunit 7; CSN7-PA; drosophila COP9 signalosome homolog 7", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG2038); (R-DME-5696394); (R-DME-6781823); (R-DME-8856825); (R-DME-8951664)", "pathway_count": 5, "publication_count": 5, "publication_id_list": "10531038;10731132;12537572;12737805;18327897", "class_list": "", "function": "Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of the SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF. The CSN complex plays an essential role in oogenesis and embryogenesis and is required for proper photoreceptor R cell differentiation and promote lamina glial cell migration or axon targeting. It also promotes Ubl-dependent degradation of cyclin E (CycE) during early oogenesis., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q6NLA1", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0034399 nuclear periphery;GO:0008180 COP9 signalosome", "go_biological_process": "GO:0050821 protein stabilization;GO:0007281 germ cell development;GO:0010387 COP9 signalosome assembly;GO:0000338 protein deneddylation;GO:0048140 male germ-line cyst encapsulation", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q9V4S8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9V4T5-1", "uniprot_id": "CP4E1_DROME", "mass": 61086.0, "length": 531, "protein_name": "Probable cytochrome P450 4e1", "gene_name": "Cyp4e1", "organism": "Fruit fly", "refseq_name": "cytochrome P450 4e1", "refseq_ac": "NP_524771", "gene_names_uniprotkb": "Cyp4e1; CG2062", "gene_names_refseq": "4e1; CG2062; CYP4E1; CYP4e1; Cyp4e1; Cyp4el; Dmel\\CG2062; P-450; P450", "protein_names_uniprotkb": "Probable cytochrome P450 4e1; 1.14.-.-; CYPIVE1", "protein_names_refseq": "CG2062-PA; Cyp4e1-PA; cytochrome P450 4e1; cytochrome P450-4e1", "tax_id": 7227, "disease": "Bietti crystalline corneoretinal dystrophy (Disease Ontology:DOID:0050664)", "pathway": " (dme:Dmel_CG2062); (R-DME-193144); (R-DME-196791); (R-DME-211916); (R-DME-211976)", "pathway_count": 5, "publication_count": 3, "publication_id_list": "10731132;12537569;12537572", "class_list": "", "function": "May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.14.-.-;1.14.15.-", "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0004497 monooxygenase activity;GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9V4T5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9V4U7-1", "uniprot_id": "C6A14_DROME", "mass": 58233.0, "length": 509, "protein_name": "Probable cytochrome P450 6a14", "gene_name": "Cyp6a14", "organism": "Fruit fly", "refseq_name": "cytochrome P450 6a14, isoform E", "refseq_ac": "NP_001286199", "gene_names_uniprotkb": "Cyp6a14; CG8687", "gene_names_refseq": "6a14; CG8687; CYP6A14; Cyp6A14; Cyp6a14; Dmel\\CG8687", "protein_names_uniprotkb": "Probable cytochrome P450 6a14; 1.14.-.-; CYPVIA14", "protein_names_refseq": "CG8687-PE; Cyp6a14-PE; cytochrome P450 6a14, isoform E; cytochrome P450", "tax_id": 7227, "disease": "alcohol dependence (Disease Ontology:DOID:0050741); alcohol-associated liver disease (Disease Ontology:DOID:0070658); B-lymphoblastic leukemia/lymphoma (Disease Ontology:DOID:0080630); prostate cancer (Disease Ontology:DOID:10283); Alzheimer's disease (Disease Ontology:DOID:10652); essential hypertension (Disease Ontology:DOID:10825); cholestasis (Disease Ontology:DOID:13580); depressive disorder (Disease Ontology:DOID:1596); anxiety disorder (Disease Ontology:DOID:2030); familial Mediterranean fever (Disease Ontology:DOID:2987); liver cirrhosis (Disease Ontology:DOID:5082); oral submucous fibrosis (Disease Ontology:DOID:5773); end stage renal disease (Disease Ontology:DOID:783); chronic myeloid leukemia (Disease Ontology:DOID:8552); acute lymphoblastic leukemia (Disease Ontology:DOID:9952)", "pathway": " (dme:Dmel_CG8687)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "10731132;12537572", "class_list": "", "function": "May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 15, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A0B4LEW9", "ec_number_list": "", "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0004497 monooxygenase activity;GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q9V4U7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9V4U9-1", "uniprot_id": "C6A13_DROME", "mass": 57644.0, "length": 493, "protein_name": "Probable cytochrome P450 6a13", "gene_name": "Cyp6a13", "organism": "Fruit fly", "refseq_name": "cytochrome P450 6a13", "refseq_ac": "NP_610390", "gene_names_uniprotkb": "Cyp6a13; CG2397", "gene_names_refseq": "6a13; CG2397; CYP6A13; Cyp6A13; Cyp6a13; Dmel\\CG2397; cyp6a13", "protein_names_uniprotkb": "Probable cytochrome P450 6a13; 1.14.-.-; CYPVIA13", "protein_names_refseq": "CG2397-PA; Cyp6a13-PA; cytochrome P450 6a13; cytochrome P450", "tax_id": 7227, "disease": "alcohol dependence (Disease Ontology:DOID:0050741); alcohol-associated liver disease (Disease Ontology:DOID:0070658); B-lymphoblastic leukemia/lymphoma (Disease Ontology:DOID:0080630); prostate cancer (Disease Ontology:DOID:10283); Alzheimer's disease (Disease Ontology:DOID:10652); essential hypertension (Disease Ontology:DOID:10825); cholestasis (Disease Ontology:DOID:13580); depressive disorder (Disease Ontology:DOID:1596); familial Mediterranean fever (Disease Ontology:DOID:2987); liver cirrhosis (Disease Ontology:DOID:5082); oral submucous fibrosis (Disease Ontology:DOID:5773); chronic myeloid leukemia (Disease Ontology:DOID:8552); acute lymphoblastic leukemia (Disease Ontology:DOID:9952)", "pathway": " (dme:Dmel_CG2397)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "10731132;12537569;12537572", "class_list": "", "function": "May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 13, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0004497 monooxygenase activity;GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0042742 defense response to bacterium", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9V4U9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9V4W1-1", "uniprot_id": "GLE1_DROME", "mass": 77360.0, "length": 677, "protein_name": "mRNA export factor Gle1", "gene_name": "Gle1", "organism": "Fruit fly", "refseq_name": "Gle1 RNA export mediator", "refseq_ac": "NP_610400", "gene_names_uniprotkb": "Gle1; CG14749", "gene_names_refseq": "CG14749; Dmel\\CG14749; GLE1; Gle1; Gle", "protein_names_uniprotkb": "mRNA export factor Gle1; Gle1 RNA export mediator; Nucleoporin Gle1", "protein_names_refseq": "CG14749-PA; Gle1 RNA export mediator; Gle1-PA", "tax_id": 7227, "disease": "lethal congenital contracture syndrome 1 (Disease Ontology:DOID:0060559)", "pathway": " (dme:Dmel_CG14749); (R-DME-159236)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "10731132;12537569;12537572", "class_list": "", "function": "Required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm. May be involved in the terminal step of the mRNA transport through the nuclear pore complex (NPC) (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005543 phospholipid binding;GO:0000822 inositol hexakisphosphate binding;GO:0031369 translation initiation factor binding", "go_cellular_component": "GO:0005635 nuclear envelope;GO:0005643 nuclear pore;GO:0005737 cytoplasm;GO:0044614 nuclear pore cytoplasmic filaments", "go_biological_process": "GO:0016973 poly(A)+ mRNA export from nucleus;GO:0006913 nucleocytoplasmic transport;GO:0015031 protein transport", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9V4W1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9V557-1", "uniprot_id": "CP4P2_DROME", "mass": 60459.0, "length": 520, "protein_name": "Probable cytochrome P450 4p2", "gene_name": "Cyp4p2", "organism": "Fruit fly", "refseq_name": "cytochrome P450 4p2", "refseq_ac": "NP_610472", "gene_names_uniprotkb": "Cyp4p2; CG1944", "gene_names_refseq": "4p2; CG1944; CYP4P2; Cyp4p2; Dmel\\CG1944", "protein_names_uniprotkb": "Probable cytochrome P450 4p2; 1.14.-.-; CYPIVP2", "protein_names_refseq": "CG1944-PA; Cyp4p2-PA; cytochrome P450 4p2; cytochrome P450", "tax_id": 7227, "disease": "Bietti crystalline corneoretinal dystrophy (Disease Ontology:DOID:0050664)", "pathway": " (dme:Dmel_CG1944); (R-DME-193144); (R-DME-196791); (R-DME-211916); (R-DME-211976)", "pathway_count": 5, "publication_count": 3, "publication_id_list": "10731132;12537569;12537572", "class_list": "", "function": "May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.14.-.-;1.14.15.-", "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0004497 monooxygenase activity;GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9V557-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9V559-1", "uniprot_id": "CP4P3_DROME", "mass": 59652.0, "length": 515, "protein_name": "Probable cytochrome P450 4p3", "gene_name": "Cyp4p3", "organism": "Fruit fly", "refseq_name": "cytochrome P450 4p3", "refseq_ac": "NP_610473", "gene_names_uniprotkb": "Cyp4p3; CG10843", "gene_names_refseq": "4p3; CG10843; Cyp4p3; Dmel\\CG10843", "protein_names_uniprotkb": "Probable cytochrome P450 4p3; 1.14.-.-; CYPIVP3", "protein_names_refseq": "CG10843-PA; Cyp4p3-PA; cytochrome P450 4p3; cytochrome P450", "tax_id": 7227, "disease": "Bietti crystalline corneoretinal dystrophy (Disease Ontology:DOID:0050664); hypertension (Disease Ontology:DOID:10763)", "pathway": " (dme:Dmel_CG10843); (R-DME-193144); (R-DME-196791); (R-DME-211916); (R-DME-211976)", "pathway_count": 5, "publication_count": 3, "publication_id_list": "10731132;12537569;12537572", "class_list": "", "function": "May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q8T8Z5", "ec_number_list": "1.14.-.-;1.14.15.-", "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0004497 monooxygenase activity;GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9V559-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9V574-1", "uniprot_id": "L2K1_DROME", "mass": 24962.0, "length": 221, "protein_name": "Protein lethal(2)k10201", "gene_name": "l(2)k10201", "organism": "Fruit fly", "refseq_name": "lethal (2) k10201", "refseq_ac": "NP_788296", "gene_names_uniprotkb": "l(2)k10201; CG13951", "gene_names_refseq": "B; CG13951; CG8803; Dmel\\CG13951; l(2)k10201", "protein_names_uniprotkb": "Protein lethal(2)k10201; Wunen region B protein", "protein_names_refseq": "CG13951-PA; l(2)k10201-PA; lethal (2) k10201", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG13951)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "10731132;12537572;8985246", "class_list": "", "function": "Vital for development., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "P91662", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9V574-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9V595-1", "uniprot_id": "DCUP_DROME", "mass": 39988.0, "length": 356, "protein_name": "Uroporphyrinogen decarboxylase", "gene_name": "Urod", "organism": "Fruit fly", "refseq_name": "uroporphyrinogen decarboxylase", "refseq_ac": "NP_610501", "gene_names_uniprotkb": "Urod; CG1818; Updo", "gene_names_refseq": "CG1818; Dmel\\CG1818; Updo; Urod", "protein_names_uniprotkb": "Uroporphyrinogen decarboxylase; 4.1.1.37; UPD; URO-D", "protein_names_refseq": "CG1818-PA; Urod-PA; updo; uroporphyrinogen decarboxylase", "tax_id": 7227, "disease": "porphyria (Disease Ontology:DOID:13268); breast cancer (Disease Ontology:DOID:1612); porphyria cutanea tarda (Disease Ontology:DOID:3132); hepatoerythropoietic porphyria (Disease Ontology:DOID:5230)", "pathway": " (dme:Dmel_CG1818); (R-DME-189451)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "10731132;12537572", "class_list": "", "function": "Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "4.1.1.37", "go_molecular_function": "GO:0004853 uroporphyrinogen decarboxylase activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0006783 heme biosynthetic process;GO:0006782 protoporphyrinogen IX biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q9V595-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9V674-1", "uniprot_id": "CP6G1_DROME", "mass": 59867.0, "length": 524, "protein_name": "Cytochrome P450 6g1", "gene_name": "Cyp6g1", "organism": "Fruit fly", "refseq_name": "cytochrome P450 6g1, isoform B", "refseq_ac": "NP_001286335", "gene_names_uniprotkb": "Cyp6g1; CG8453; CYP6-like; DDT-R; Rst(2)DDT", "gene_names_refseq": "6g1; CG8453; CYP6G1; CYP6g1; Cyp6-like; Cyp6G1; Cyp6g1; Cyp6gl; DDT-R; Dmel-Cyp6g1; Dmel\\CG8453; RDDT; RI[DDT]; RI[II]; RI; Rst(2)DDT; anon-WO03025223.16; anon-WO03025223.17; cyp6g1", "protein_names_uniprotkb": "Cytochrome P450 6g1; 1.14.-.-; CYPVIG1; Cyp6-like protein", "protein_names_refseq": "CG8453-PB; CYP6-like; Cyp6g1-PB; cytochrome P450 6g1, isoform B; cytochrome P450; resistance to DDT; resistance to Insecticide-DDT; resistance to insecticide on chromosome 2", "tax_id": 7227, "disease": "alcohol dependence (Disease Ontology:DOID:0050741); alcohol-associated liver disease (Disease Ontology:DOID:0070658); B-lymphoblastic leukemia/lymphoma (Disease Ontology:DOID:0080630); prostate cancer (Disease Ontology:DOID:10283); Alzheimer's disease (Disease Ontology:DOID:10652); essential hypertension (Disease Ontology:DOID:10825); cholestasis (Disease Ontology:DOID:13580); depressive disorder (Disease Ontology:DOID:1596); anxiety disorder (Disease Ontology:DOID:2030); familial Mediterranean fever (Disease Ontology:DOID:2987); liver cirrhosis (Disease Ontology:DOID:5082); oral submucous fibrosis (Disease Ontology:DOID:5773); end stage renal disease (Disease Ontology:DOID:783); chronic myeloid leukemia (Disease Ontology:DOID:8552); acute lymphoblastic leukemia (Disease Ontology:DOID:9952)", "pathway": " (dme:Dmel_CG8453)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "10731132;11810226;12351787;12537569;12537572;15663776;16783023;17134855", "class_list": "", "function": "Necessary and sufficient for resistance to insecticides DDT and imidacloprid. May be involved in the metabolism of insect hormones., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 15, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "O76800;Q0GT65;Q3KN31;Q5MAT9;Q5MAU2;Q95SI8", "ec_number_list": "", "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0004497 monooxygenase activity;GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0046683 response to organophosphorus;GO:0046689 response to mercury ion;GO:0017085 response to insecticide;GO:0046680 response to DDT;GO:0046701 insecticide catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q9V674-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9V676-1", "uniprot_id": "CP6T3_DROME", "mass": 57845.0, "length": 501, "protein_name": "Probable cytochrome P450 6t3", "gene_name": "Cyp6t3", "organism": "Fruit fly", "refseq_name": "cytochrome P450 6t3", "refseq_ac": "NP_610745", "gene_names_uniprotkb": "Cyp6t3; CG8457", "gene_names_refseq": "6t3; CG8457; Cyp6T3; Cyp6t3; Dmel\\CG8457; bb; cyp6t3", "protein_names_uniprotkb": "Probable cytochrome P450 6t3; 1.14.-.-; CYPVIT3", "protein_names_refseq": "CG8457-PA; Cyp6t3-PA; cytochrome P450 6t3", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG8457)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "10731132;12537572", "class_list": "", "function": "May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0004497 monooxygenase activity;GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0048638 regulation of developmental growth;GO:0046680 response to DDT;GO:0046701 insecticide catabolic process;GO:0006697 ecdysone biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q9V676-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9V677-1", "uniprot_id": "ECM29_DROME", "mass": 212087.0, "length": 1890, "protein_name": "Proteasome-associated protein ECM29 homolog", "gene_name": "CG8858", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": "NP_610746", "gene_names_uniprotkb": "CG8858", "gene_names_refseq": "CG8858; Dmel\\CG8858", "protein_names_uniprotkb": "Proteasome-associated protein ECM29 homolog", "protein_names_refseq": "CG8858-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG8858)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "10731132;12537572;17372656;18327897", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q7K1A6", "ec_number_list": "", "go_molecular_function": "GO:0060090 molecular adaptor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0000502 proteasome complex", "go_biological_process": "GO:0036503 ERAD pathway;GO:0043248 proteasome assembly", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q9V677-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9V6H1-1", "uniprot_id": "CP9H1_DROME", "mass": 60045.0, "length": 518, "protein_name": "Probable cytochrome P450 9h1", "gene_name": "Cyp9h1", "organism": "Fruit fly", "refseq_name": "cytochrome P450 9h1", "refseq_ac": "NP_610820", "gene_names_uniprotkb": "Cyp9h1; CG17577", "gene_names_refseq": "9h1; CG17577; CYP9H1; Cyp9h1; Dmel\\CG17577", "protein_names_uniprotkb": "Probable cytochrome P450 9h1; 1.14.-.-; CYPIXH1", "protein_names_refseq": "CG17577-PA; Cyp9h1-PA; cytochrome P450 9h1; cytochrome P450", "tax_id": 7227, "disease": "alcohol dependence (Disease Ontology:DOID:0050741); thrombosis (Disease Ontology:DOID:0060903); alcohol-associated liver disease (Disease Ontology:DOID:0070658); B-lymphoblastic leukemia/lymphoma (Disease Ontology:DOID:0080630); acute necrotizing pancreatitis (Disease Ontology:DOID:0080998); hypertension (Disease Ontology:DOID:10763); essential hypertension (Disease Ontology:DOID:10825); membranous glomerulonephritis (Disease Ontology:DOID:10976); hydronephrosis (Disease Ontology:DOID:11111); cholestasis (Disease Ontology:DOID:13580); depressive disorder (Disease Ontology:DOID:1596); anxiety disorder (Disease Ontology:DOID:2030); arteriosclerosis (Disease Ontology:DOID:2349); glomerulonephritis (Disease Ontology:DOID:2921); familial Mediterranean fever (Disease Ontology:DOID:2987); brain infarction (Disease Ontology:DOID:3454); liver cirrhosis (Disease Ontology:DOID:5082); oral submucous fibrosis (Disease Ontology:DOID:5773); end stage renal disease (Disease Ontology:DOID:783); chronic myeloid leukemia (Disease Ontology:DOID:8552); pulmonary embolism (Disease Ontology:DOID:9477); acute lymphoblastic leukemia (Disease Ontology:DOID:9952)", "pathway": " (dme:Dmel_CG17577)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "10731132;12537572", "class_list": "", "function": "May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 22, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0004497 monooxygenase activity;GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q9V6H1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9V6U9-1", "uniprot_id": "MECR_DROME", "mass": 39111.0, "length": 357, "protein_name": "Enoyl-[acyl-carrier-protein] reductase, mitochondrial", "gene_name": "Mecr", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform B", "refseq_ac": "NP_001286396", "gene_names_uniprotkb": "Mecr; CG16935", "gene_names_refseq": "CG16935; DM_7303260; Dmel\\CG16935", "protein_names_uniprotkb": "Enoyl-[acyl-carrier-protein] reductase, mitochondrial; 1.3.1.104; 2-enoyl thioester reductase; Mitochondrial trans-2-enoyl-CoA reductase", "protein_names_refseq": "CG16935-PB; Enoyl-[acyl-carrier-protein] reductase, mitochondrial; trans-2-enoyl-CoA reductase, mitochondrial; uncharacterized protein, isoform B", "tax_id": 7227, "disease": "childhood-onset dystonia with optic atrophy and basal ganglia abnormalities (Disease Ontology:DOID:0081419); Leber hereditary optic neuropathy with demyelinating disease of CNS (Disease Ontology:DOID:0111756); optic atrophy (Disease Ontology:DOID:5723)", "pathway": " (dme:Dmel_CG16935); (R-DME-77346)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "10731132;12537572;37653044", "class_list": "", "function": "Catalyzes the NADPH-dependent reduction of trans-2-enoyl thioesters in mitochondrial fatty acid synthesis (fatty acid synthesis type II). Fatty acid chain elongation in mitochondria uses acyl carrier protein (ACP) as an acyl group carrier, but the enzyme accepts both ACP and CoA thioesters as substrates in vitro (By similarity). Involved in iron homeostasis; affecting Fe-S cluster assembly and ceramide metabolism (PubMed:37653044). Required for proper morphology and bioenergetic functions of mitochondria (PubMed:37653044). Required for maintenance of neurons, including photoreceptor neurons (PubMed:37653044)., [UniProtKB, UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "H8F4T6", "ec_number_list": "1.1.1.100;1.3.1.39;2.3.1.38;2.3.1.39;2.3.1.41;2.3.1.85;3.1.2.14;4.2.1.59;1.3.1.104", "go_molecular_function": "GO:0141148 enoyl-[acyl-carrier-protein] reductase (NADPH) activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0016020 membrane", "go_biological_process": "GO:0006631 fatty acid metabolic process;GO:0046513 ceramide biosynthetic process;GO:0006633 fatty acid biosynthetic process;GO:0006879 intracellular iron ion homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9V6U9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9V726-1", "uniprot_id": "CPSF1_DROME", "mass": 164681.0, "length": 1455, "protein_name": "Cleavage and polyadenylation specificity factor subunit 1", "gene_name": "Cpsf160", "organism": "Fruit fly", "refseq_name": "cleavage and polyadenylation specificity factor 160, isoform B", "refseq_ac": "NP_725397", "gene_names_uniprotkb": "Cpsf160; CG10110; cpsf", "gene_names_refseq": "CG10110; CPSF-160; CPSF160; CPSF; Cpsf160; Cpsf; Dmel\\CG10110; anon-WO0118547.217; cpsf; dCPSF-160", "protein_names_uniprotkb": "Cleavage and polyadenylation specificity factor subunit 1; CPSF 160 kDa subunit; Cleavage and polyadenylation specificity factor 160 kDa subunit; dCPSF 160", "protein_names_refseq": "CG10110-PB; Cpsf160-PB; cleavage and polyadenylation specificity factor 160, isoform B; cleavage and polyadenylation specificity factor; drosophila cleavage and polyadenylation stimulation factor-160", "tax_id": 7227, "disease": "myopia (Disease Ontology:DOID:11830)", "pathway": " (dme:Dmel_CG10110); (R-DME-159231); (R-DME-73856); (R-DME-77595); (R-DME-9770562)", "pathway_count": 5, "publication_count": 5, "publication_id_list": "10731132;12537569;12537572;19450530;9604891", "class_list": "", "function": "Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. This subunit is involved in the RNA recognition step of the polyadenylation reaction (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q7KR84;Q960R9;Q9GV83;Q9GV84;Q9GV85", "ec_number_list": "", "go_molecular_function": "GO:0017022 myosin binding;GO:0035925 mRNA 3'-UTR AU-rich region binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005847 mRNA cleavage and polyadenylation specificity factor complex", "go_biological_process": "GO:0031124 mRNA 3'-end processing", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q9V726-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9V771-1", "uniprot_id": "C6A23_DROME", "mass": 58089.0, "length": 502, "protein_name": "Probable cytochrome P450 6a23", "gene_name": "Cyp6a23", "organism": "Fruit fly", "refseq_name": "cytochrome P450 6a23", "refseq_ac": "NP_611000", "gene_names_uniprotkb": "Cyp6a23; CG10242", "gene_names_refseq": "6a23; CG10242; CYP6A23; Cyp6A23; Cyp6a23; Cypa23; Dmel\\CG10242; cyp6a23", "protein_names_uniprotkb": "Probable cytochrome P450 6a23; 1.14.-.-; CYPVIA23", "protein_names_refseq": "CG10242-PA; Cyp6a23-PA; cytochrome P450 6a23; cytochrome P450", "tax_id": 7227, "disease": "alcohol dependence (Disease Ontology:DOID:0050741); alcohol-associated liver disease (Disease Ontology:DOID:0070658); B-lymphoblastic leukemia/lymphoma (Disease Ontology:DOID:0080630); prostate cancer (Disease Ontology:DOID:10283); Alzheimer's disease (Disease Ontology:DOID:10652); essential hypertension (Disease Ontology:DOID:10825); cholestasis (Disease Ontology:DOID:13580); depressive disorder (Disease Ontology:DOID:1596); anxiety disorder (Disease Ontology:DOID:2030); familial Mediterranean fever (Disease Ontology:DOID:2987); liver cirrhosis (Disease Ontology:DOID:5082); oral submucous fibrosis (Disease Ontology:DOID:5773); end stage renal disease (Disease Ontology:DOID:783); chronic myeloid leukemia (Disease Ontology:DOID:8552); acute lymphoblastic leukemia (Disease Ontology:DOID:9952)", "pathway": " (dme:Dmel_CG10242)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "10731132;12537569;12537572", "class_list": "", "function": "May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 15, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q8SYE8", "ec_number_list": "", "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0004497 monooxygenase activity;GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9V771-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9V773-1", "uniprot_id": "C6A20_DROME", "mass": 57729.0, "length": 501, "protein_name": "Probable cytochrome P450 6a20", "gene_name": "Cyp6a20", "organism": "Fruit fly", "refseq_name": "cytochrome P450 6a20", "refseq_ac": "NP_611002", "gene_names_uniprotkb": "Cyp6a20; CG10245", "gene_names_refseq": "6a20; CG10245; CYP6a20; Cyp6a20; Dmel\\CG10245; agg; cyp6a20; p450", "protein_names_uniprotkb": "Probable cytochrome P450 6a20; 1.14.-.-; CYPVIA20", "protein_names_refseq": "CG10245-PB; Cyp6a20-PB; cytochrome P450 6a20", "tax_id": 7227, "disease": "alcohol dependence (Disease Ontology:DOID:0050741); alcohol-associated liver disease (Disease Ontology:DOID:0070658); B-lymphoblastic leukemia/lymphoma (Disease Ontology:DOID:0080630); prostate cancer (Disease Ontology:DOID:10283); Alzheimer's disease (Disease Ontology:DOID:10652); essential hypertension (Disease Ontology:DOID:10825); cholestasis (Disease Ontology:DOID:13580); depressive disorder (Disease Ontology:DOID:1596); anxiety disorder (Disease Ontology:DOID:2030); familial Mediterranean fever (Disease Ontology:DOID:2987); liver cirrhosis (Disease Ontology:DOID:5082); oral submucous fibrosis (Disease Ontology:DOID:5773); end stage renal disease (Disease Ontology:DOID:783); chronic myeloid leukemia (Disease Ontology:DOID:8552); acute lymphoblastic leukemia (Disease Ontology:DOID:9952)", "pathway": " (dme:Dmel_CG10245)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "10731132;12537569;12537572", "class_list": "", "function": "May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 15, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "B5RJG1;Q95R69", "ec_number_list": "", "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0004497 monooxygenase activity;GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0050829 defense response to Gram-negative bacterium;GO:0002118 aggressive behavior", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9V773-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9V774-1", "uniprot_id": "C6A21_DROME", "mass": 57842.0, "length": 504, "protein_name": "Probable cytochrome P450 6a21", "gene_name": "Cyp6a21", "organism": "Fruit fly", "refseq_name": "cytochrome P450 6a21", "refseq_ac": "NP_611003", "gene_names_uniprotkb": "Cyp6a21; CG10247", "gene_names_refseq": "6a21; AF4-2; CG10247; CYP6A21; Cyp6A21; Cyp6a21; Cyp6a9-rAF4-2; Dmel\\CG10247; P-450; P450; cyp6a21", "protein_names_uniprotkb": "Probable cytochrome P450 6a21; 1.14.-.-; CYPVIA21", "protein_names_refseq": "CG10247-PA; Cyp6a21-PA; Cyp6a9-related; cytochrome P450 6a21; cytochrome P450-6a9 related AF4-2; cytochrome P450", "tax_id": 7227, "disease": "alcohol dependence (Disease Ontology:DOID:0050741); prostate cancer (Disease Ontology:DOID:10283); Alzheimer's disease (Disease Ontology:DOID:10652); cholestasis (Disease Ontology:DOID:13580); depressive disorder (Disease Ontology:DOID:1596); anxiety disorder (Disease Ontology:DOID:2030); liver cirrhosis (Disease Ontology:DOID:5082); end stage renal disease (Disease Ontology:DOID:783)", "pathway": " (dme:Dmel_CG10247)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "10731132;12537569;12537572", "class_list": "", "function": "May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 8, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A8E6J3;Q8SZL2", "ec_number_list": "", "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0004497 monooxygenase activity;GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9V774-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9V776-1", "uniprot_id": "CP317_DROME", "mass": 60279.0, "length": 518, "protein_name": "Probable cytochrome P450 317a1", "gene_name": "Cyp317a1", "organism": "Fruit fly", "refseq_name": "cytochrome P450 317a1, isoform B", "refseq_ac": "NP_001286435", "gene_names_uniprotkb": "Cyp317a1; CG17453", "gene_names_refseq": "317a1; CG17453; Cyp317A1; Cyp317a1; Dmel\\CG17453", "protein_names_uniprotkb": "Probable cytochrome P450 317a1; 1.14.-.-; CYPCCCXVIIA1", "protein_names_refseq": "CG17453-PB; Cyp317a1-PB; cytochrome P450 317a1, isoform B", "tax_id": 7227, "disease": "prostate cancer (Disease Ontology:DOID:10283); Alzheimer's disease (Disease Ontology:DOID:10652)", "pathway": " (dme:Dmel_CG17453)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "10731132;12537572", "class_list": "", "function": "May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "C9QPG6", "ec_number_list": "", "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0004497 monooxygenase activity;GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q9V776-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9V778-1", "uniprot_id": "ADAS_DROME", "mass": 70822.0, "length": 631, "protein_name": "Alkylglycerone-phosphate synthase", "gene_name": "Agps", "organism": "Fruit fly", "refseq_name": "alkylglycerone phosphate synthase, isoform D", "refseq_ac": "NP_001188935", "gene_names_uniprotkb": "Agps; ADPS; CG10253", "gene_names_refseq": "ADPS; AGPS; Agps; CG10253; Dmel\\CG10253; dAGPS", "protein_names_uniprotkb": "Alkylglycerone-phosphate synthase; 2.5.1.26; Alkyl-DHAP synthase; Alkyldihydroxyacetonephosphate synthase", "protein_names_refseq": "Agps-PD; CG10253-PD; alkyldihydroxyacetonephosphate synthase; alkylglycerone phosphate synthase, isoform D", "tax_id": 7227, "disease": "rhizomelic chondrodysplasia punctata type 3 (Disease Ontology:DOID:0110853); rhizomelic chondrodysplasia punctata (Disease Ontology:DOID:2580)", "pathway": " (dme:Dmel_CG10253); (R-DME-75896); (R-DME-9033241)", "pathway_count": 3, "publication_count": 3, "publication_id_list": "10731132;12537569;12537572", "class_list": "", "function": "Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "A0A0B4JD21", "ec_number_list": "2.3.1.42;2.5.1.26;2.3.2.27", "go_molecular_function": "GO:0008609 alkylglycerone-phosphate synthase activity;GO:0071949 FAD binding", "go_cellular_component": "GO:0005777 peroxisome", "go_biological_process": "GO:0008610 lipid biosynthetic process;GO:0008611 ether lipid biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9V778-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9V7A4-1", "uniprot_id": "ITA4_DROME", "mass": 118911.0, "length": 1069, "protein_name": "Integrin alpha-PS4", "gene_name": "ItgaPS4", "organism": "Fruit fly", "refseq_name": "integrin alphaPS4 subunit", "refseq_ac": "NP_611025", "gene_names_uniprotkb": "ItgaPS4; CG16827; ItgalphaPS4; alphaPS4", "gene_names_refseq": "CG16827; CT37393; Dmel\\CG16827; ItgaPS4; ItgalphaPS4; alpha-PS4; alpha-ps4; alphaPS4", "protein_names_uniprotkb": "Integrin alpha-PS4; Position-specific antigen subunit alpha-4", "protein_names_refseq": "CG16827-PA; ItgaPS4-PA; alphaPS4 integrin; integrin alphaPS4 subunit", "tax_id": 7227, "disease": "stroke (Disease Ontology:DOID:0051061); von Willebrand's disease 1 (Disease Ontology:DOID:0060573); von Willebrand's disease 2 (Disease Ontology:DOID:0060574); thrombosis (Disease Ontology:DOID:0060903); sensorineural hearing loss (Disease Ontology:DOID:10003); hypertension (Disease Ontology:DOID:10763); iron deficiency anemia (Disease Ontology:DOID:11758); Behcet's disease (Disease Ontology:DOID:13241); thrombocytopenia (Disease Ontology:DOID:1588); breast cancer (Disease Ontology:DOID:1612); retinal vein occlusion (Disease Ontology:DOID:1727); pancreatic cancer (Disease Ontology:DOID:1793); Glanzmann's thrombasthenia (Disease Ontology:DOID:2219); arteriosclerosis (Disease Ontology:DOID:2349); cerebral infarction (Disease Ontology:DOID:3526); placental insufficiency (Disease Ontology:DOID:3891); lung non-small cell carcinoma (Disease Ontology:DOID:3908); myocardial infarction (Disease Ontology:DOID:5844); intermediate coronary syndrome (Disease Ontology:DOID:8805); diabetic retinopathy (Disease Ontology:DOID:8947); diabetes mellitus (Disease Ontology:DOID:9351); type 2 diabetes mellitus (Disease Ontology:DOID:9352)", "pathway": " (dme:Dmel_CG16827); (R-DME-198933); (R-DME-202733); (R-DME-210991); (R-DME-216083); (R-DME-3000170); (R-DME-445144); (R-DME-445355); (R-DME-6798695)", "pathway_count": 9, "publication_count": 6, "publication_id_list": "10731132;12537572;19035354;20689801;21124962;22438831", "class_list": "", "function": "Possible role in cell adhesion. Minor involvement in the establishment of the oocyte anterior-posterior length., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 12, "predicted_n_glycosites": 12, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 22, "glyco_site_count": 12, "binding_glycan_count": 0, "secondary_ac_list": "G2J626;Q4V4A2", "ec_number_list": "", "go_molecular_function": "GO:0046982 protein heterodimerization activity;GO:0038023 signaling receptor activity", "go_cellular_component": "GO:0009986 cell surface;GO:0016020 membrane;GO:0008305 integrin complex", "go_biological_process": "GO:0007229 integrin-mediated signaling pathway;GO:0007160 cell-matrix adhesion;GO:0033627 cell adhesion mediated by integrin;GO:0098609 cell-cell adhesion;GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q9V7A4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9V7A7-1", "uniprot_id": "GPAN1_DROME", "mass": 38523.0, "length": 336, "protein_name": "G patch domain and ankyrin repeat-containing protein 1 homolog", "gene_name": "CG8152", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": "NP_611028", "gene_names_uniprotkb": "CG8152", "gene_names_refseq": "CG8152; Dmel\\CG8152", "protein_names_uniprotkb": "G patch domain and ankyrin repeat-containing protein 1 homolog", "protein_names_refseq": "CG8152-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG8152)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "10731132;12537569;12537572", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q8SWS4", "ec_number_list": "", "go_molecular_function": "GO:0003676 nucleic acid binding", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9V7A7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9V7G5-1", "uniprot_id": "C4AA1_DROME", "mass": 58536.0, "length": 510, "protein_name": "Probable cytochrome P450 4aa1", "gene_name": "Cyp4aa1", "organism": "Fruit fly", "refseq_name": "cytochrome P450 4aa1", "refseq_ac": "NP_611067", "gene_names_uniprotkb": "Cyp4aa1; CG8302", "gene_names_refseq": "4aa1; CG8302; CYP4AA1; Cyp4AA1; Cyp4aa1; Dmel\\CG8302", "protein_names_uniprotkb": "Probable cytochrome P450 4aa1; 1.14.-.-; CYPIVAA1", "protein_names_refseq": "CG8302-PB; Cyp4aa1-PB; cytochrome P450 4aa1; cytochrome P450", "tax_id": 7227, "disease": "Bietti crystalline corneoretinal dystrophy (Disease Ontology:DOID:0050664)", "pathway": " (dme:Dmel_CG8302); (R-DME-193144); (R-DME-196791); (R-DME-211916); (R-DME-211976)", "pathway_count": 5, "publication_count": 2, "publication_id_list": "10731132;12537572", "class_list": "", "function": "May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q1RKQ6", "ec_number_list": "1.14.-.-;1.14.15.-", "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0004497 monooxygenase activity;GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q9V7G5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9V831-1", "uniprot_id": "APC10_DROME", "mass": 22300.0, "length": 195, "protein_name": "Anaphase-promoting complex subunit 10", "gene_name": "APC10", "organism": "Fruit fly", "refseq_name": "anaphase promoting complex subunit 10", "refseq_ac": "NP_611223", "gene_names_uniprotkb": "APC10; CG11419", "gene_names_refseq": "APC10; Apc10; CG11419; Dmel\\CG11419", "protein_names_uniprotkb": "Anaphase-promoting complex subunit 10; APC10; Cyclosome subunit 10", "protein_names_refseq": "APC10-PA; CG11419-PA; anaphase promoting complex subunit 10", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG11419); (R-DME-141430); (R-DME-174048); (R-DME-174084); (R-DME-174154); (R-DME-174178); (R-DME-174184); (R-DME-176407); (R-DME-176408); (R-DME-176409); (R-DME-176412); (R-DME-179409); (R-DME-2467813); (R-DME-2559582); (R-DME-68867); (R-DME-69017); (R-DME-983168)", "pathway_count": 17, "publication_count": 3, "publication_id_list": "10731132;12537569;12537572", "class_list": "", "function": "Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q8MTU6", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005680 anaphase-promoting complex", "go_biological_process": "GO:0000278 mitotic cell cycle;GO:0051301 cell division;GO:0007346 regulation of mitotic cell cycle;GO:0016567 protein ubiquitination;GO:0031145 anaphase-promoting complex-dependent catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9V831-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9V8F5-1", "uniprot_id": "BM23_DROME", "mass": 11552.0, "length": 117, "protein_name": "Bomanin Bicipital 1", "gene_name": "BomBc1", "organism": "Fruit fly", "refseq_name": "bomanin bicipital 1", "refseq_ac": "NP_611318", "gene_names_uniprotkb": "BomBc1; Bom23; CG15066; IM23", "gene_names_refseq": "BcDNA:RH67033; Bom23; BomBc1; CG15066; DIM 23; DIM-23; Dmel\\CG15066; IM23", "protein_names_uniprotkb": "Bomanin Bicipital 1; Bomanin-23; DIM-23; DIM23; Immune-induced peptide 23", "protein_names_refseq": "BomBc1-PA; CG15066-PA; Immune-induced peptide 23 precursor; bomanin 23; bomanin Bc1; bomanin bicipital 1; immune induced molecule 23", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG15066)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "10731132;12537569;12537572;25915418;29920489;9736738", "class_list": "", "function": "Secreted immune-induced peptide induced by Toll signaling (PubMed:9736738). Has a role in resistance to bacterial and fungal infections (PubMed:25915418, PubMed:29920489)., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q8SY64", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0019731 antibacterial humoral response;GO:0045087 innate immune response;GO:0050830 defense response to Gram-positive bacterium;GO:0009617 response to bacterium;GO:0010046 response to mycotoxin", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q9V8F5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9V8I2-1", "uniprot_id": "LTOR2_DROME", "mass": 13439.0, "length": 125, "protein_name": "Ragulator complex protein LAMTOR2 homolog", "gene_name": "Lamtor2", "organism": "Fruit fly", "refseq_name": "late endosomal/lysosomal adaptor, MAPK and MTOR activator 2, isoform B", "refseq_ac": "NP_001137699", "gene_names_uniprotkb": "Lamtor2; CG5189", "gene_names_refseq": "CG5189; Dmel\\CG5189; Lamtor2; dp14; p14", "protein_names_uniprotkb": "Ragulator complex protein LAMTOR2 homolog; Late endosomal/lysosomal adaptor and MAPK and MTOR activator 2", "protein_names_refseq": "CG5189-PB; Lamtor2-PB; late endosomal/lysosomal adaptor, MAPK and MTOR activator 2, isoform B", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG5189); (R-DME-1632852); (R-DME-165159); (R-DME-166208); (R-DME-380972); (R-DME-5628897); (R-DME-5674135); (R-DME-6798695); (R-DME-8943724); (R-DME-9639288)", "pathway_count": 10, "publication_count": 3, "publication_id_list": "10731132;12537572;20381137", "class_list": "", "function": "Regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factors, energy levels, and amino acids. As part of the Ragulator complex, may activate the TOR signaling cascade in response to amino acids., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A8E6I2;B7YZK0;Q6NP73", "ec_number_list": "", "go_molecular_function": "GO:0060090 molecular adaptor activity;GO:0005085 guanyl-nucleotide exchange factor activity", "go_cellular_component": "GO:0071986 Ragulator complex", "go_biological_process": "GO:1904263 positive regulation of TORC1 signaling;GO:0001558 regulation of cell growth;GO:0032008 positive regulation of TOR signaling;GO:0008104 intracellular protein localization;GO:0038202 TORC1 signaling", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9V8I2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9V8K2-1", "uniprot_id": "EXOC3_DROME", "mass": 86664.0, "length": 738, "protein_name": "Exocyst complex component 3", "gene_name": "Sec6", "organism": "Fruit fly", "refseq_name": "secretory 6", "refseq_ac": "NP_611351", "gene_names_uniprotkb": "Sec6; CG5341", "gene_names_refseq": "CG5341; Dmel\\CG5341; Dsec6; Sec6p; Sec6; dsec6; sec 6; sec6", "protein_names_uniprotkb": "Exocyst complex component 3; Exocyst complex component Sec6", "protein_names_refseq": "CG5341-PA; Sec6 ortholog; Sec6-PA; secretory 6", "tax_id": 7227, "disease": "focal segmental glomerulosclerosis (Disease Ontology:DOID:1312)", "pathway": " (dme:Dmel_CG5341); (R-DME-264876); (R-DME-5620916)", "pathway_count": 3, "publication_count": 3, "publication_id_list": "10731132;12537569;12537572", "class_list": "", "function": "Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q95TT4", "ec_number_list": "", "go_molecular_function": "GO:0000149 SNARE binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0016020 membrane;GO:0098793 presynapse;GO:0005915 zonula adherens;GO:0000145 exocyst", "go_biological_process": "GO:0051601 exocyst localization;GO:0016080 synaptic vesicle targeting;GO:0072697 protein localization to cell cortex;GO:0007009 plasma membrane organization;GO:0072659 protein localization to plasma membrane", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9V8K2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9V8M5-1", "uniprot_id": "3HIDH_DROME", "mass": 33883.0, "length": 324, "protein_name": "3-hydroxyisobutyrate dehydrogenase, mitochondrial", "gene_name": "Hibadh", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform E", "refseq_ac": "NP_001188972", "gene_names_uniprotkb": "Hibadh; CG15093", "gene_names_refseq": "CG 15093; CG15093; CT34968; Dmel\\CG15093", "protein_names_uniprotkb": "3-hydroxyisobutyrate dehydrogenase, mitochondrial; 1.1.1.31", "protein_names_refseq": "3-hydroxyisobutyrate dehydrogenase; CG15093-PE; uncharacterized protein, isoform E", "tax_id": 7227, "disease": "amino acid metabolic disorder (Disease Ontology:DOID:9252)", "pathway": " (dme:Dmel_CG15093); (R-DME-70895)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "10731132;12537572", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A0B4JCU8;Q0E926;Q86R98;Q9V8M6", "ec_number_list": "1.1.1.31", "go_molecular_function": "GO:0051287 NAD binding;GO:0008442 3-hydroxyisobutyrate dehydrogenase activity;GO:0050661 NADP binding", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0006574 L-valine catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q9V8M5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9V969-1", "uniprot_id": "GR57A_DROME", "mass": 47529.0, "length": 416, "protein_name": "Putative gustatory receptor 57a", "gene_name": "Gr57a", "organism": "Fruit fly", "refseq_name": "gustatory receptor 57a", "refseq_ac": "NP_523798", "gene_names_uniprotkb": "Gr57a; CG13441; GR57B.1", "gene_names_refseq": "57B.1; CG13441; Dmel\\CG13441; GR57B.1; GR57a; Gr57B1; Gr57a", "protein_names_uniprotkb": "Putative gustatory receptor 57a", "protein_names_refseq": "CG13441-PA; Gr57a-PA; gustatory receptor 57B.1; gustatory receptor 57a", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG13441)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "10710312;10731132;11516643;12537572;22031876", "class_list": "", "function": "Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0015276 ligand-gated monoatomic ion channel activity;GO:0008527 taste receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane;GO:0030424 axon;GO:0030425 dendrite;GO:0043025 neuronal cell body", "go_biological_process": "GO:0008049 male courtship behavior;GO:0007165 signal transduction;GO:0034220 monoatomic ion transmembrane transport;GO:0007635 chemosensory behavior;GO:0050909 sensory perception of taste", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q9V969-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9V9Z9-1", "uniprot_id": "EBP2_DROME", "mass": 35077.0, "length": 307, "protein_name": "Probable rRNA-processing protein EBP2 homolog", "gene_name": "CG1542", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": "NP_651850", "gene_names_uniprotkb": "CG1542", "gene_names_refseq": "CG1542; Dmel\\CG1542; EBP2", "protein_names_uniprotkb": "Probable rRNA-processing protein EBP2 homolog", "protein_names_refseq": "CG1542-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG1542); (R-DME-6791226)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "10731132;12537569;12537572", "class_list": "", "function": "Required for the processing of the 27S pre-rRNA., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding", "go_cellular_component": "GO:0005730 nucleolus;GO:0030687 preribosome, large subunit precursor;GO:0034399 nuclear periphery", "go_biological_process": "GO:0042273 ribosomal large subunit biogenesis;GO:0006364 rRNA processing", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9V9Z9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VA02-1", "uniprot_id": "DHTK1_DROME", "mass": 103635.0, "length": 919, "protein_name": "Probable 2-oxoadipate dehydrogenase complex component E1 homolog", "gene_name": "Oadh", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": "NP_651849", "gene_names_uniprotkb": "Oadh; CG1544", "gene_names_refseq": "CG1544; Dmel\\CG1544", "protein_names_uniprotkb": "Probable 2-oxoadipate dehydrogenase complex component E1 homolog; 1.2.4.-", "protein_names_refseq": "CG1544-PA; uncharacterized protein", "tax_id": 7227, "disease": "Charcot-Marie-Tooth disease axonal type 2Q (Disease Ontology:DOID:0110170); 2-aminoadipic 2-oxoadipic aciduria (Disease Ontology:DOID:0111453)", "pathway": " (dme:Dmel_CG1544); (R-DME-9858328)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "10731132;12537569;12537572", "class_list": "", "function": "2-oxoadipate dehydrogenase (E1a) component of the 2-oxoadipate dehydrogenase complex (OADHC). Participates in the first step, rate limiting for the overall conversion of 2-oxoadipate (alpha-ketoadipate) to glutaryl-CoA and CO(2) catalyzed by the whole OADHC. Catalyzes the irreversible decarboxylation of 2-oxoadipate via the thiamine diphosphate (ThDP) cofactor and subsequent transfer of the decarboxylated acyl intermediate on an oxidized dihydrolipoyl group that is covalently amidated to the E2 enzyme (dihydrolipoyllysine-residue succinyltransferase or DLST)., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q8IGV6;Q8MT95;T2FGC6", "ec_number_list": "1.2.4.-;2.3.1.61;1.8.1.4", "go_molecular_function": "GO:0030976 thiamine pyrophosphate binding;GO:0160166 2-oxoadipate dehydrogenase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0160167 oxoadipate dehydrogenase complex", "go_biological_process": "GO:0006091 generation of precursor metabolites and energy;GO:0006099 tricarboxylic acid cycle;GO:0006103 2-oxoglutarate metabolic process;GO:0006096 glycolytic process;GO:0019442 L-tryptophan catabolic process to acetyl-CoA", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9VA02-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VAC5-1", "uniprot_id": "ADA17_DROME", "mass": 83081.0, "length": 732, "protein_name": "ADAM 17-like protease", "gene_name": "Tace", "organism": "Fruit fly", "refseq_name": "tace, isoform B", "refseq_ac": "NP_651759", "gene_names_uniprotkb": "Tace; CG7908", "gene_names_refseq": "ADAM17; CG7908; CT23908; DTACE; Dmel\\CG7908; TACE; TNF-alpha converting enzyme; Tace; tace", "protein_names_uniprotkb": "ADAM 17-like protease; 3.4.24.-", "protein_names_refseq": "CG7908-PB; Tace-PB; tace, isoform B; tumor necrosis factor-alpha-converting enzyme", "tax_id": 7227, "disease": "renal fibrosis (Disease Ontology:DOID:0050855); neonatal inflammatory skin and bowel disease 1 (Disease Ontology:DOID:0061192); Alzheimer's disease (Disease Ontology:DOID:10652); thoracic aortic aneurysm (Disease Ontology:DOID:14004); atopic dermatitis (Disease Ontology:DOID:3310); congestive heart failure (Disease Ontology:DOID:6000); type 2 diabetes mellitus (Disease Ontology:DOID:9352)", "pathway": " (dme:Dmel_CG7908)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "10731132;12537572", "class_list": "", "function": "", "predicted_glycosites": 4, "predicted_n_glycosites": 4, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 7, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "Q868A7;Q8IMJ9;Q95RZ4", "ec_number_list": "", "go_molecular_function": "GO:0004222 metalloendopeptidase activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane", "go_biological_process": "GO:1903427 negative regulation of reactive oxygen species biosynthetic process;GO:0006509 membrane protein ectodomain proteolysis;GO:0007219 Notch signaling pathway;GO:0007220 Notch receptor processing;GO:0040015 negative regulation of multicellular organism growth", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q9VAC5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VAD6-1", "uniprot_id": "COG7_DROME", "mass": 84076.0, "length": 742, "protein_name": "Conserved oligomeric Golgi complex subunit 7", "gene_name": "Cog7", "organism": "Fruit fly", "refseq_name": "component of oligomeric golgi complex 7", "refseq_ac": "NP_651750", "gene_names_uniprotkb": "Cog7; CG31040", "gene_names_refseq": "CG31040; CG7880; Cog7; Dmel\\CG31040", "protein_names_uniprotkb": "Conserved oligomeric Golgi complex subunit 7; COG complex subunit 7; Component of oligomeric Golgi complex 7", "protein_names_refseq": "CG31040-PA; Cog7-PA; component of oligomeric golgi complex 7", "tax_id": 7227, "disease": "congenital disorder of glycosylation type IIe (Disease Ontology:DOID:0070257); genetic disease (Disease Ontology:DOID:630)", "pathway": " (dme:Dmel_CG31040); (R-DME-6807878); (R-DME-6811438); (R-DME-6811440)", "pathway_count": 4, "publication_count": 3, "publication_id_list": "10731132;12537569;12537572", "class_list": "", "function": "Required for normal Golgi function., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q8SZV9", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005794 Golgi apparatus;GO:0017119 Golgi transport complex;GO:0036063 acroblast", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0006890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum;GO:0007030 Golgi organization;GO:1903292 protein localization to Golgi membrane;GO:0000301 retrograde transport, vesicle recycling within Golgi", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9VAD6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VAF5-1", "uniprot_id": "CAD99_DROME", "mass": 186874.0, "length": 1706, "protein_name": "Cadherin-99C", "gene_name": "Cad99C", "organism": "Fruit fly", "refseq_name": "cadherin 99C, isoform B", "refseq_ac": "NP_001189311", "gene_names_uniprotkb": "Cad99C; CG31009", "gene_names_refseq": "CA-10; CG15511; CG310034; CG31009; CG7805; CT35624; CT4930; Cad99C; Cad99c; DCad99C; Dm Cad99C; Dmel\\CG31009; cad99C", "protein_names_uniprotkb": "Cadherin-99C", "protein_names_refseq": "CG31009-PB; Cad99C-PB; Cadherin99C; cadherin 99C, isoform B", "tax_id": 7227, "disease": "autosomal recessive nonsyndromic deafness 23 (Disease Ontology:DOID:0110481); Usher syndrome type 1D (Disease Ontology:DOID:0110831); Usher syndrome type 1F (Disease Ontology:DOID:0110832)", "pathway": " (dme:Dmel_CG31009)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "10731132;12537572;15708564;16260500;16507588;24718992;25236597;25639794;27331610", "class_list": "", "function": "Cadherin that functions in epithelial morphogenesis and the intestine epithelial immune response (PubMed:16260500, PubMed:16507588, PubMed:24718992, PubMed:25639794). Essential for female fertility (PubMed:16260500, PubMed:16507588). Regulates the length and organization of apical microvilli in developing follicle cells and salivary glands (PubMed:16260500, PubMed:16507588, PubMed:24718992, PubMed:25236597). Function in the follicle cell is essential for egg development as the microvilli secrete eggshell material such as the vitelline membrane (PubMed:16260500, PubMed:16507588, PubMed:25236597). Acts at least in part by regulating the recruitment of the myosin ck to the follicle cell microvilli (PubMed:25236597). Also required to regulate cell rearrangements during salivary tube elongation, possibly by modulating cellular adhesion between the apical surface and apical extracellular matrix during epithelial tube elongation (PubMed:24718992). May also function in cellular adhesion during the development of other tubular epithelia such as the trachea (PubMed:24718992). Possibly functions as an apical membrane determinant which acts in apical membrane expansion during salivary and tracheal epithelial tube elongation (PubMed:24718992). In salivary gland development, this function is independent of the other apical membrane determinants crb and sas (PubMed:24718992). Essential downstream component of a hh-signaling pathway which regulates the Duox-dependent gut epithelial immune response to bacterial uracil; required for endosome formation in the enterocyte and activating norpA-dependent Ca2+ mobilization, which are essential steps in the Duox-dependent production of reactive oxygen species (ROS) in response to intestinal bacterial infection (PubMed:25639794)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 12, "predicted_n_glycosites": 11, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 12, "binding_glycan_count": 0, "secondary_ac_list": "Q5D716;Q5U133;Q961C6;Q9VAF6", "ec_number_list": "", "go_molecular_function": "GO:0005509 calcium ion binding;GO:0017022 myosin binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005912 adherens junction;GO:0016324 apical plasma membrane;GO:0010008 endosome membrane;GO:0005902 microvillus", "go_biological_process": "GO:0007409 axonogenesis;GO:0019722 calcium-mediated signaling;GO:0030855 epithelial cell differentiation;GO:0007605 sensory perception of sound;GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "Q9VAF5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VAM6-1", "uniprot_id": "CISD2_DROME", "mass": 14633.0, "length": 133, "protein_name": "CDGSH iron-sulfur domain protein", "gene_name": "Cisd", "organism": "Fruit fly", "refseq_name": "CDGSH iron sulfur domain 2", "refseq_ac": "NP_651684", "gene_names_uniprotkb": "Cisd; CG1458; Cisd2", "gene_names_refseq": "BcDNA:RE49709; CG1458; Cisd2; Dmel\\CG1458; Dosmit; Dsm; MitoNEET; cisd2; dWFS2; mitoNEET", "protein_names_uniprotkb": "CDGSH iron-sulfur domain protein; CDGSH iron-sulfur domain-containing protein-2 homolog", "protein_names_refseq": "CDGSH iron sulfur domain 2; CG1458-PA; Cisd2-PA; downsizing mitochondria", "tax_id": 7227, "disease": "Wolfram syndrome 2 (Disease Ontology:DOID:0110630)", "pathway": " (dme:Dmel_CG1458)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "10731132;12537569;12537572", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0046872 metal ion binding;GO:0047801 L-cysteine transaminase activity;GO:0051537 2 iron, 2 sulfur cluster binding", "go_cellular_component": "GO:0005741 mitochondrial outer membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006839 mitochondrial transport;GO:0010506 regulation of autophagy;GO:0006879 intracellular iron ion homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9VAM6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VAP2-1", "uniprot_id": "DGT6_DROME", "mass": 72827.0, "length": 654, "protein_name": "Augmin complex subunit dgt6", "gene_name": "dgt6", "organism": "Fruit fly", "refseq_name": "dim gamma-tubulin 6", "refseq_ac": "NP_651671", "gene_names_uniprotkb": "dgt6; CG11881", "gene_names_refseq": "CG11881; Dgt6; Dmel\\CG11881; dgt6; msd4", "protein_names_uniprotkb": "Augmin complex subunit dgt6; Dim gamma-tubulin 6", "protein_names_refseq": "CG11881-PA; dgt6-PA; dim gamma-tubulin 6; mitotic spindle density 4", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG11881)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "10731132;12537569;12537572;17412918;18443220;19369198;19836241;23785300;24829288", "class_list": "", "function": "As part of the augmin complex, plays a role in centrosome-independent generation of spindle microtubules (PubMed:18443220). The complex is required for mitotic spindle assembly through its involvement in localizing gamma-tubulin to spindle microtubules (PubMed:17412918). dgt6 is required for kinetochore fiber formation, mediating nucleation and/or initial stabilization of chromosome-induced microtubules (PubMed:19836241)., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008017 microtubule binding;GO:0030674 protein-macromolecule adaptor activity", "go_cellular_component": "GO:0000922 spindle pole;GO:0005813 centrosome;GO:0005819 spindle;GO:0000776 kinetochore;GO:0070652 HAUS complex", "go_biological_process": "GO:0010968 regulation of microtubule nucleation;GO:0051301 cell division;GO:0090307 mitotic spindle assembly;GO:0000226 microtubule cytoskeleton organization;GO:0007088 regulation of mitotic nuclear division", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "Q9VAP2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VAP3-1", "uniprot_id": "CTL12_DROME", "mass": 90629.0, "length": 796, "protein_name": "Choline transporter-like 2", "gene_name": "Ctl2", "organism": "Fruit fly", "refseq_name": "choline transporter-like 2, isoform A", "refseq_ac": "NP_651670", "gene_names_uniprotkb": "Ctl2; CG11880", "gene_names_refseq": "CG11880; CTLH2; Ctl2; DmCTL2; Dmel\\CG11880", "protein_names_uniprotkb": "Choline transporter-like 2", "protein_names_refseq": "CG11880-PA; Ctl2-PA; choline transporter (CTL)-like protein 2; choline transporter-like 2, isoform A", "tax_id": 7227, "disease": "autosomal dominant nonsyndromic deafness 72 (Disease Ontology:DOID:0080268); sensorineural hearing loss (Disease Ontology:DOID:10003)", "pathway": " (dme:Dmel_CG11880); (R-DME-1483191); (R-DME-6798163); (R-DME-6798695); (R-DME-9958517)", "pathway_count": 5, "publication_count": 2, "publication_id_list": "10731132;12537572", "class_list": "", "function": "", "predicted_glycosites": 5, "predicted_n_glycosites": 5, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0022857 transmembrane transporter activity", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "GO:0055085 transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q9VAP3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VAQ5-1", "uniprot_id": "DIM1_DROME", "mass": 35048.0, "length": 306, "protein_name": "Probable dimethyladenosine transferase", "gene_name": "CG11837", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": "NP_651660", "gene_names_uniprotkb": "CG11837", "gene_names_refseq": "CG11837; Dim1; Dmel\\CG11837", "protein_names_uniprotkb": "Probable dimethyladenosine transferase; 2.1.1.183; Probable 18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase; Probable 18S rRNA dimethylase; Probable S-adenosylmethionine-6-N',N'-adenosyl(rRNA) dimethyltransferase", "protein_names_refseq": "CG11837-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG11837)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "10731132;12537569;12537572", "class_list": "", "function": "Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA in the 40S particle. Involved in the pre-rRNA processing steps leading to small-subunit rRNA production independently of its RNA-modifying catalytic activity. Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.1.1.183", "go_molecular_function": "GO:0003723 RNA binding;GO:0052909 18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase activity;GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity", "go_cellular_component": "GO:0005730 nucleolus;GO:0032040 small-subunit processome", "go_biological_process": "GO:0031167 rRNA methylation;GO:0042274 ribosomal small subunit biogenesis", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9VAQ5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VAW5-3", "uniprot_id": "LARP_DROME", "mass": 178145.0, "length": 1673, "protein_name": "La-related protein 1", "gene_name": "larp", "organism": "Fruit fly", "refseq_name": "La related protein, isoform E", "refseq_ac": "NP_001163757", "gene_names_uniprotkb": "larp; CG42551", "gene_names_refseq": "0031/08; 0225/29; BcDNA:LD02611; CG14065; CG14066; CG42551; Dmel\\CG42551; Larp; dlarp; l(3)S003108; l(3)S022529; larp1; larp", "protein_names_uniprotkb": "La-related protein 1; dLarp", "protein_names_refseq": "CG42551-PE; La related protein, isoform E; La-related protein; drosophila La related protein; larp-PE; lethal (3) S003108; lethal (3) S022529; meteor", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG42551)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;10878606;12537569;12537572;14668392;17372656;17951964;18327897;19631203;30772175;35413237", "class_list": "", "function": "RNA-binding protein that regulates the translation of specific target mRNA species downstream of the mTORC1 complex, in function of growth signals and nutrient availability. Interacts on the one hand with the 3' poly-A tails that are present in all mRNA molecules, and on the other hand with the 7-methylguanosine cap structure of mRNAs containing a 5' terminal oligopyrimidine (5'TOP) motif, which is present in mRNAs encoding ribosomal proteins and several components of the translation machinery (PubMed:17951964, PubMed:19631203, PubMed:30772175, PubMed:35413237). The interaction with the 5' end of mRNAs containing a 5'TOP motif leads to translational repression. Associates with actively translating ribosomes and stimulates translation of mRNAs containing a 5'TOP motif, thereby regulating protein synthesis, and as a consequence, cell growth and proliferation (PubMed:35413237)., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 4, "predicted_n_glycosites": 0, "predicted_o_glycosites": 4, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 28, "reported_mutagensis": 15, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "A4V3J4;D0IQE9;E1JJ02;Q8IMM4;Q8MSZ4;Q8MYR3;Q9NHN6;Q9VAW4", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding;GO:0008187 poly-pyrimidine tract binding;GO:0048027 mRNA 5'-UTR binding;GO:0000339 RNA cap binding", "go_cellular_component": "GO:0031315 extrinsic component of mitochondrial outer membrane;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0010494 cytoplasmic stress granule", "go_biological_process": "GO:2000767 positive regulation of cytoplasmic translation;GO:0090297 positive regulation of mitochondrial DNA replication;GO:0048255 mRNA stabilization;GO:1903955 positive regulation of protein targeting to mitochondrion;GO:0045727 positive regulation of translation", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VAW5-3", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VAY7-1", "uniprot_id": "FAM50_DROME", "mass": 42857.0, "length": 359, "protein_name": "Protein FAM50 homolog", "gene_name": "CG12259", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": "NP_651595", "gene_names_uniprotkb": "CG12259", "gene_names_refseq": "CG12259; Dmel\\CG12259", "protein_names_uniprotkb": "Protein FAM50 homolog", "protein_names_refseq": "CG12259-PA; uncharacterized protein", "tax_id": 7227, "disease": "Armfield syndrome (Disease Ontology:DOID:0050764)", "pathway": " (dme:Dmel_CG12259); (R-DME-72163)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "10731132;12537569;12537572", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm", "go_biological_process": "GO:0006325 chromatin organization", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9VAY7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VB62-1", "uniprot_id": "DPOA2_DROME", "mass": 66971.0, "length": 609, "protein_name": "DNA polymerase alpha subunit B", "gene_name": "PolA2", "organism": "Fruit fly", "refseq_name": "DNA polymerase alpha subunit 2", "refseq_ac": "NP_733206", "gene_names_uniprotkb": "PolA2; CG5923; DNApol-alpha73", "gene_names_refseq": "CG5923; DNA pol-73; DNA polalpha; DNA polymerase alpha 73 kD; DNApol-alpha72; DNApol-alpha73; DNApol-alpha; DNApolalpha; Dmel\\CG5923; Dmpol alpha; POLA; PolA2; Polalpha 73KDa; Polalpha 73kDa; Polalpha73; Polalpha; Pol; pol alpha; polalpha", "protein_names_uniprotkb": "DNA polymerase alpha subunit B; DNA polymerase alpha 73 kDa subunit", "protein_names_refseq": "B subunit; CG5923-PC; DNA polymerase 73K; DNA polymerase alpha 73,000 alpha subunit; DNA polymerase alpha 73kD subunit; DNA polymerase alpha 73kD; DNA polymerase alpha primase 73 kda subunit; DNA polymerase alpha subunit 2; DNA-polymerase alpha; DNApol-alpha73; PolA2-PC", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG5923); (R-DME-113501); (R-DME-68952); (R-DME-68962); (R-DME-69091); (R-DME-69166); (R-DME-69183)", "pathway_count": 7, "publication_count": 10, "publication_id_list": "10731132;12537569;12537572;1508723;18327897;6403945;6409898;6773966;7592543;9918845", "class_list": "", "function": "Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis (PubMed:6403945, PubMed:6409898, PubMed:6773966, PubMed:7592543). During the S phase of the cell cycle, the DNA polymerase alpha complex (composed of a catalytic subunit PolA1, an accessory subunit PolA2 and two primase subunits, the catalytic subunit Prim1 and the regulatory subunit Prim2) is recruited to DNA at the replicative forks (By similarity). The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. These primers are initially extended by the polymerase alpha catalytic subunit and subsequently transferred to polymerase delta and polymerase epsilon for processive synthesis on the lagging and leading strand, respectively (By similarity)., [UniProtKB, UniProtKB, UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q95S59;Q9TXB0", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding", "go_cellular_component": "GO:0005658 alpha DNA polymerase:primase complex;GO:0005634 nucleus;GO:0005635 nuclear envelope", "go_biological_process": "GO:0006270 DNA replication initiation;GO:0006261 DNA-templated DNA replication", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "Q9VB62-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VBB3-1", "uniprot_id": "INT12_DROME", "mass": 34334.0, "length": 328, "protein_name": "Integrator complex subunit 12", "gene_name": "IntS12", "organism": "Fruit fly", "refseq_name": "integrator 12", "refseq_ac": "NP_651507", "gene_names_uniprotkb": "IntS12; CG5491", "gene_names_refseq": "CG5491; Dmel\\CG5491; Int12; IntS12", "protein_names_uniprotkb": "Integrator complex subunit 12", "protein_names_refseq": "CG5491-PA; IntS12-PA; integrator 12", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG5491); (R-DME-6807505)", "pathway_count": 2, "publication_count": 10, "publication_id_list": "10731132;12537569;12537572;21078872;23097424;23288851;31530651;32966759;37995689;39032490", "class_list": "", "function": "Component of the integrator complex, a multiprotein complex that terminates RNA polymerase II (Pol II) transcription in the promoter-proximal region of genes (PubMed:21078872, PubMed:23097424, PubMed:23288851, PubMed:32966759). The integrator complex provides a quality checkpoint during transcription elongation by driving premature transcription termination of transcripts that are unfavorably configured for transcriptional elongation: the complex terminates transcription by (1) catalyzing dephosphorylation of the C-terminal domain (CTD) of Pol II subunit Polr2A/Rbp1 and Spt5, and (2) degrading the exiting nascent RNA transcript via endonuclease activity (PubMed:32966759). The integrator complex is also involved in the 3'-end processing of the U7 snRNA, and also the spliceosomal snRNAs U1, U2, U4 and U5 (PubMed:21078872, PubMed:23097424, PubMed:23288851). Required for the normal expression of the Integrator complex component IntS1 (PubMed:23288851)., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0032039 integrator complex;GO:0160232 INTAC complex", "go_biological_process": "GO:0016180 snRNA processing;GO:0034472 snRNA 3'-end processing;GO:0160240 RNA polymerase II transcription initiation surveillance", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "Q9VBB3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VBL6-1", "uniprot_id": "MS57A_DROME", "mass": 7106.0, "length": 75, "protein_name": "Accessory gland-specific peptide 57Da", "gene_name": "Mst57Da", "organism": "Fruit fly", "refseq_name": "Male-specific RNA 57Da", "refseq_ac": "NP_524906", "gene_names_uniprotkb": "Mst57Da; CG9074", "gene_names_refseq": "BcDNA:GH19893; CG9074; Dmel\\CG9074; Mst57Da; Mst57D; bs30d07.y1; mst(2)ag-1; mst-1; mst57D", "protein_names_uniprotkb": "Accessory gland-specific peptide 57Da; Male accessory gland secretory protein 57Da", "protein_names_refseq": "CG9074-PA; Male-specific RNA 57Da; Mst57Da-PA", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG9074)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "10731132;12537569;12537572;7711745", "class_list": "", "function": "Transferred from male to female during mating and may affect egglaying and behavior after mating., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q24390;Q8MSH9", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005576 extracellular region;GO:0005615 extracellular space", "go_biological_process": "GO:0007320 insemination;GO:0007618 mating;GO:0045924 regulation of female receptivity;GO:0018991 egg-laying behavior", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q9VBL6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VBW9-1", "uniprot_id": "DANR_DROME", "mass": 45273.0, "length": 419, "protein_name": "Protein distal antenna-related", "gene_name": "danr", "organism": "Fruit fly", "refseq_name": "distal antenna-related", "refseq_ac": "NP_651343", "gene_names_uniprotkb": "danr; CG13651", "gene_names_refseq": "CG13651; Danr; Dmel\\CG13651; danr; hern", "protein_names_uniprotkb": "Protein distal antenna-related", "protein_names_refseq": "CG13651-PA; danr-PA; distal antenna related; distal antenna-related; hernandez; tintin", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG13651)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "10731132;12537569;12537572;12571108;17493605", "class_list": "", "function": "Probable transcription factor with a role in the retinal determination (RD) network. Regulates ato expression and is required for normal R8 induction and differentiation. Danr appears to repress Dan expression, but Dan is required for Danr expression anterior to the morphogenetic furrow (MF). Dan and Danr lie downstream of so and require dac function for highest levels of expression. Contributes to differentiation of antenna-specific characteristics; effector gene that acts downstream of homothorax (hth), Distal-less (Dll), cut (ct) and spineless (ss) genes to control differentiation of distal antennal structures., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0003700 DNA-binding transcription factor activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0048749 compound eye development;GO:0006351 DNA-templated transcription;GO:0006355 regulation of DNA-templated transcription;GO:0007379 segment specification;GO:0007469 antennal development", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q9VBW9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VBX2-1", "uniprot_id": "MOC2B_DROME", "mass": 41891.0, "length": 367, "protein_name": "Molybdopterin synthase catalytic subunit", "gene_name": "Mocs2B", "organism": "Fruit fly", "refseq_name": "molybdenum cofactor synthesis 2B", "refseq_ac": "NP_651340", "gene_names_uniprotkb": "Mocs2B; CG10238; Mocs2", "gene_names_refseq": "CG10238; Dmel\\CG10238; Dromel_CG10238_FBtr0084782_mocs_mORF; MBIP/dMoaE; MOCS2; Mbip; Mocs2B; Mocs2b; Mocs2; dMbip; dMoaE", "protein_names_uniprotkb": "Molybdopterin synthase catalytic subunit; 2.8.1.12; MOCS2B; Molybdenum cofactor synthesis protein 2 large subunit; Molybdenum cofactor synthesis protein 2B", "protein_names_refseq": "CG10238-PA; MAPK upstream kinase-binding inhibitory protein; MUK-binding inhibitory protein; Mocs2B-PA; molybdenum cofactor synthesis 2B; molybdenum cofactor synthesis 2; molybdopterin synthase 2", "tax_id": 7227, "disease": "molybdenum cofactor deficiency type B (Disease Ontology:DOID:0111163)", "pathway": " (dme:Dmel_CG10238)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "10731132;12537569;12537572;18237443;18327268;29491838", "class_list": "", "function": "Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated Mocs2A into precursor Z to generate a dithiolene group (By similarity). Involved during biosynthesis of the molybdenum cofactor (Probable)., [UniProtKB, HAMAP, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q961W4", "ec_number_list": "2.8.1.12", "go_molecular_function": "GO:0030366 molybdopterin synthase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0005700 polytene chromosome;GO:0140672 ATAC complex;GO:1990140 molybdopterin synthase complex", "go_biological_process": "GO:0006338 chromatin remodeling;GO:0006355 regulation of DNA-templated transcription;GO:0006777 Mo-molybdopterin cofactor biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q9VBX2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VC45-1", "uniprot_id": "ASP_DROME", "mass": 230180.0, "length": 1954, "protein_name": "Protein abnormal spindle", "gene_name": "asp", "organism": "Fruit fly", "refseq_name": "abnormal spindle", "refseq_ac": "NP_524488", "gene_names_uniprotkb": "asp; CG6875", "gene_names_refseq": "ASP; Asp; CG6875; Dm Asp; Dmel\\CG6875; anon-96Aa; anon-WO0118547.279; asp", "protein_names_uniprotkb": "Protein abnormal spindle", "protein_names_refseq": "CG6875-PA; abnormal spindle protein; abnormal spindles; abnormal spindle; asp-PA", "tax_id": 7227, "disease": "primary autosomal recessive microcephaly 5 (Disease Ontology:DOID:0070280); autosomal recessive primary microcephaly (Disease Ontology:DOID:0070296); stomach cancer (Disease Ontology:DOID:10534); microcephaly (Disease Ontology:DOID:10907); ovary epithelial cancer (Disease Ontology:DOID:2152); glioblastoma (Disease Ontology:DOID:3068); high grade glioma (Disease Ontology:DOID:3070); hepatocellular carcinoma (Disease Ontology:DOID:684)", "pathway": " (dme:Dmel_CG6875)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "10073938;10731132;12537569;12537572;15242765;18327897;32066907;9151690", "class_list": "", "function": "Required to maintain the structure of the centrosomal microtubule organizing center (MTOC) during mitosis. May have a preferential role in regulating neurogenesis. Required for germ cell mitosis and oocyte differentiation., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 13, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 8, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "O01401;Q8SX66", "ec_number_list": "", "go_molecular_function": "GO:0005516 calmodulin binding;GO:0008017 microtubule binding;GO:0032027 myosin light chain binding", "go_cellular_component": "GO:0000922 spindle pole;GO:0005634 nucleus;GO:0005813 centrosome;GO:0005874 microtubule;GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "GO:0051383 kinetochore organization;GO:0000278 mitotic cell cycle;GO:0030036 actin cytoskeleton organization;GO:0000226 microtubule cytoskeleton organization;GO:0048854 brain morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q9VC45-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VC70-1", "uniprot_id": "DZIP1_DROME", "mass": 83822.0, "length": 737, "protein_name": "Cilium assembly protein DZIP1L", "gene_name": "DZIP1", "organism": "Fruit fly", "refseq_name": "DZIP1, isoform B", "refseq_ac": "NP_001262918", "gene_names_uniprotkb": "DZIP1; CG13617", "gene_names_refseq": "CG13617; DZIP1; Dmel\\CG13617; Dzip1; dzip1", "protein_names_uniprotkb": "Cilium assembly protein DZIP1L; DAZ-interacting zinc finger protein 1-like; Zinc finger protein DZIP1", "protein_names_refseq": "CG13617-PB; DZIP1, isoform B; DZIP1-PB; iguana", "tax_id": 7227, "disease": "polycystic kidney disease 5 (Disease Ontology:DOID:0080273); autosomal recessive polycystic kidney disease (Disease Ontology:DOID:0110861); spermatogenic failure 47 (Disease Ontology:DOID:0112175); coloboma (Disease Ontology:DOID:12270); mitral valve prolapse (Disease Ontology:DOID:988)", "pathway": " (dme:Dmel_CG13617); (R-DME-5632684)", "pathway_count": 2, "publication_count": 4, "publication_id_list": "10731132;12537572;31821146;33370260", "class_list": "", "function": "Component of the DZIP1-Fam92-Cby complex which promotes ciliogenesis in sensory neurons and spermatocytes by acting downstream of Cep290 to initiate early ciliary membrane formation and thus transition zone (TZ) assembly (PubMed:31821146, PubMed:33370260). During spermatogenesis, also regulates distal elongation of the basal-body and their docking (anchoring) to the plasma membrane and as a consequence, regulates the initiation and proper elongation of axonemal microtubules (PubMed:31821146). Within the complex, required to recruit or stabilize Rab8, Fam92 and Cby at the distal basal body of cilia to promote early ciliary membrane formation and initiate TZ assembly (PubMed:31821146). Also acts with Fam92 to restrict Cep290 localization to the proximal part of the TZ (PubMed:31821146). May also be involved in recruitment or stabilization of Mks1 at the TZ (PubMed:31821146)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0030425 dendrite;GO:0005814 centriole;GO:0036064 ciliary basal body;GO:0035869 ciliary transition zone", "go_biological_process": "GO:0060271 cilium assembly", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q9VC70-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VCD0-1", "uniprot_id": "GATB_DROME", "mass": 57376.0, "length": 516, "protein_name": "Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial", "gene_name": "GatB", "organism": "Fruit fly", "refseq_name": "Glutamyl-tRNA amidotransferase, subunit B", "refseq_ac": "NP_651217", "gene_names_uniprotkb": "GatB; CG5463", "gene_names_refseq": "CG5463; Dmel\\CG5463; GatB", "protein_names_uniprotkb": "Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial; 6.3.5.-; Glu-AdT subunit B", "protein_names_refseq": "CG5463-PA; GatB-PA; Glutamyl-tRNA amidotransferase, subunit B; glutamyl-tRNA amidotransferase subunit B", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG5463)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "10731132;12537572", "class_list": "", "function": "Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "6.3.5.-;6.3.5.7", "go_molecular_function": "GO:0005524 ATP binding;GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex", "go_biological_process": "GO:0032543 mitochondrial translation;GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q9VCD0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VCU9-1", "uniprot_id": "DCR1_DROME", "mass": 255330.0, "length": 2249, "protein_name": "Endoribonuclease Dcr-1", "gene_name": "Dcr-1", "organism": "Fruit fly", "refseq_name": "Dicer-1", "refseq_ac": "NP_524453", "gene_names_uniprotkb": "Dcr-1; CG4792", "gene_names_refseq": "CG4792; DCR-1; DCR1; DICER-1; DICER; Dcr-1; Dcr1; Dcr; Dicer1; Dicer; Dmel\\CG4792; cg4792; dcr 1; dcr-1; dcr1; dicer-1; dicer1; dicer; dmDcr1", "protein_names_uniprotkb": "Endoribonuclease Dcr-1; 3.1.26.3; Protein dicer-1", "protein_names_refseq": "CG4792-PA; DICER1; Dcr-1-PA; Dicer-1; dicer 1", "tax_id": 7227, "disease": "multinodular goiter (Disease Ontology:DOID:0050489); diffuse large B-cell lymphoma (Disease Ontology:DOID:0050745); nephroma (Disease Ontology:DOID:0080615); DICER1 syndrome (Disease Ontology:DOID:0081063); stomach cancer (Disease Ontology:DOID:10534); DiGeorge syndrome (Disease Ontology:DOID:11198); dilated cardiomyopathy (Disease Ontology:DOID:12930); middle cerebral artery infarction (Disease Ontology:DOID:3525); pleuropulmonary blastoma (Disease Ontology:DOID:4769); hepatocellular carcinoma (Disease Ontology:DOID:684); colorectal cancer (Disease Ontology:DOID:9256)", "pathway": " (dme:Dmel_CG4792); (R-DME-203927); (R-DME-426486)", "pathway_count": 3, "publication_count": 22, "publication_id_list": "10731132;11201747;11498593;12368261;12537569;12537572;15066283;15918769;15985611;16949822;17666393;17928574;18327897;19451544;19635780;20400939;21419681;21926993;23063653;24488111;36182693;40245499", "class_list": "", "function": "Endoribonuclease which functions in microRNA- (miRNA) gene silencing and, independently of its ribonuclease III activity, also acts in the short interfering RNA- (siRNA) gene silencing pathway (PubMed:11201747, PubMed:11498593, PubMed:15066283, PubMed:15918769, PubMed:15985611, PubMed:17666393, PubMed:17928574, PubMed:19451544, PubMed:19635780, PubMed:21419681, PubMed:21926993, PubMed:24488111, PubMed:36182693). Cleaves hairpin precursor miRNAs (pre-miRNA) to generate mature miRNAs (miRNAs) that are between twenty-one to twenty-four nucleotides in length and function in RNA silencing and post-transcriptional regulation of gene expression (PubMed:15066283, PubMed:15918769, PubMed:15985611, PubMed:17666393, PubMed:17928574, PubMed:19451544, PubMed:19635780, PubMed:21419681, PubMed:21926993, PubMed:23063653, PubMed:24488111, PubMed:36182693). Also functions in miRNA loading and assembly of the Argonaute 1 (AGO1)-containing RNA-induced silencing complex (miRISC), with the miRNAs serving as a guide to direct the miRISC to complementary RNAs to degrade them or prevent their translation (PubMed:15066283, PubMed:17928574, PubMed:19451544). Independently of its catalytic activity, functions in the siRNA silencing pathway by promoting assembly of the siRNA-directed Argonaute 2 (AGO2)-containing RISC (siRISC) (PubMed:15066283). Required for the proper formation of a stable intermediate (R2) in siRISC assembly, which is formed from the R1 precursor complex (containing Dcr-2, R2D2 and the siRNA) and is used for assembly of the mature (R3) siRISC complex (PubMed:15066283). It is not required for siRNA biogenesis (PubMed:15066283, PubMed:21419681). During embryogenesis, involved in germline fate determination (PubMed:16949822). Post-transcriptionally regulates mei-P26 expression through the microRNA pathway, which in turn post-translationally regulates myc protein levels; involved in regulating cell and tissue growth (PubMed:20400939)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 4, "predicted_n_glycosites": 0, "predicted_o_glycosites": 4, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 3, "reported_mutagensis": 5, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 11, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "Q961S7", "ec_number_list": "3.1.26.3", "go_molecular_function": "GO:0003723 RNA binding;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0003727 single-stranded RNA binding;GO:0004521 RNA endonuclease activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0016442 RISC complex;GO:0070578 RISC-loading complex", "go_biological_process": "GO:0070922 RISC complex assembly;GO:0042594 response to starvation;GO:0048813 dendrite morphogenesis;GO:0031054 pre-miRNA processing;GO:0035194 regulatory ncRNA-mediated post-transcriptional gene silencing", "synthesized_glycan_count": 0, "hit_score": 2.5, "record_id": "Q9VCU9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VD74-1", "uniprot_id": "GR93C_DROME", "mass": 46253.0, "length": 397, "protein_name": "Putative gustatory receptor 93c", "gene_name": "Gr93c", "organism": "Fruit fly", "refseq_name": "gustatory receptor 93c", "refseq_ac": "NP_732665", "gene_names_uniprotkb": "Gr93c; CG31173; GR93F.3", "gene_names_refseq": "93F.3; CG13411; CG31173; Dmel\\CG31173; GR93F.3; GR93c; Gr93F3; Gr93c", "protein_names_uniprotkb": "Putative gustatory receptor 93c", "protein_names_refseq": "CG31173-PA; Gr93c-PA; gustatory receptor 93F.3; gustatory receptor 93c", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG31173)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "10710312;10731132;11516643;12537572;22031876", "class_list": "", "function": "Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0015276 ligand-gated monoatomic ion channel activity;GO:0008527 taste receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane;GO:0030424 axon;GO:0030425 dendrite;GO:0043025 neuronal cell body", "go_biological_process": "GO:0008049 male courtship behavior;GO:0007165 signal transduction;GO:0034220 monoatomic ion transmembrane transport;GO:0007635 chemosensory behavior;GO:0050909 sensory perception of taste", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q9VD74-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VD76-1", "uniprot_id": "GR93A_DROME", "mass": 48834.0, "length": 419, "protein_name": "Gustatory receptor for bitter taste 93a", "gene_name": "Gr93a", "organism": "Fruit fly", "refseq_name": "gustatory receptor 93a", "refseq_ac": "NP_524442", "gene_names_uniprotkb": "Gr93a; CG13417; GR93F.1", "gene_names_refseq": "93F.1; CG13417; Dmel\\CG13417; GR93F.1; GR93a; GR93; Gr93F1; Gr93a", "protein_names_uniprotkb": "Gustatory receptor for bitter taste 93a", "protein_names_refseq": "CG13417-PA; Gr93a-PA; gustatory receptor 93F.1; gustatory receptor 93a", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG13417)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "10710312;10731132;11516643;12537572;19246397;22031876", "class_list": "", "function": "Gustatory receptor required for response to the bitter in taste neurons. Gr93a cells respond to bitter compounds such as caffeine. Flies avoid bitter substances, suggesting that Gr93a neuron activity is sufficient to mediate avoidance behavior., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0015276 ligand-gated monoatomic ion channel activity;GO:0008527 taste receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane;GO:0030424 axon;GO:0030425 dendrite;GO:0043025 neuronal cell body", "go_biological_process": "GO:0008049 male courtship behavior;GO:0007165 signal transduction;GO:0031000 response to caffeine;GO:0034220 monoatomic ion transmembrane transport;GO:0007635 chemosensory behavior", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q9VD76-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VDE6-1", "uniprot_id": "EXOC6_DROME", "mass": 88726.0, "length": 766, "protein_name": "Exocyst complex component 6", "gene_name": "Sec15", "organism": "Fruit fly", "refseq_name": "secretory 15", "refseq_ac": "NP_650942", "gene_names_uniprotkb": "Sec15; CG7034", "gene_names_refseq": "3R41; CG7034; Dmel\\CG7034; Sec15p; Sec15; dsec15; sec15", "protein_names_uniprotkb": "Exocyst complex component 6; Exocyst complex component Sec15", "protein_names_refseq": "CG7034-PA; Sec15 ortholog; Sec15-PA; secretory 15", "tax_id": 7227, "disease": "spondyloepimetaphyseal dysplasia with joint laxity type 3 (Disease Ontology:DOID:0112200)", "pathway": " (dme:Dmel_CG7034); (R-DME-264876); (R-DME-5620916)", "pathway_count": 3, "publication_count": 3, "publication_id_list": "10731132;12537572;16155582", "class_list": "", "function": "Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 3, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q53YF7", "ec_number_list": "", "go_molecular_function": "GO:0031267 small GTPase binding", "go_cellular_component": "GO:0005768 endosome;GO:0043679 axon terminus;GO:0055037 recycling endosome;GO:0031410 cytoplasmic vesicle;GO:0000145 exocyst", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0072659 protein localization to plasma membrane;GO:0016192 vesicle-mediated transport;GO:0000281 mitotic cytokinesis;GO:0006887 exocytosis", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9VDE6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VDH6-1", "uniprot_id": "IR93A_DROME", "mass": 99639.0, "length": 868, "protein_name": "Ionotropic receptor 93a", "gene_name": "Ir93a", "organism": "Fruit fly", "refseq_name": "ionotropic receptor 93a", "refseq_ac": "NP_650924", "gene_names_uniprotkb": "Ir93a; CG42315", "gene_names_refseq": "93a; CG17274; CG17275; CG42315; CT35907; DmelIR93a; Dmel\\CG42315; IR93a; IR93; Ir93a; ir93a", "protein_names_uniprotkb": "Ionotropic receptor 93a", "protein_names_refseq": "CG42315-PD; Ir93a-PD; ionotropic receptor 93a", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG42315)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "10731132;12537569;12537572;27161501;27656904", "class_list": "", "function": "Integral part of various neural sensory systems in the antenna that provide the neural basis for the response to environmental changes in temperature (thermosensation) and humidity (hygrosensation) (PubMed:27161501, PubMed:27656904). Together with Ir21a and Ir25a, mediates the response of the larval dorsal organ cool cells, a trio of cool-responsive neurons, to cooling and is required for cool avoidance behavior (PubMed:27161501, PubMed:27656904). Together with Ir25a and Ir40a, mediates the response of the hydrosensory sacculus neurons to changes in relative humidity, and is required for dry detection and humidiy preference behavior (PubMed:27161501, PubMed:27656904)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 9, "predicted_n_glycosites": 9, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 9, "binding_glycan_count": 0, "secondary_ac_list": "Q8IH81;Q8T0V7;Q9VDH7", "ec_number_list": "", "go_molecular_function": "GO:0015276 ligand-gated monoatomic ion channel activity;GO:1904315 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential;GO:0008066 glutamate receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane;GO:0098839 postsynaptic density membrane", "go_biological_process": "GO:0050907 detection of chemical stimulus involved in sensory perception;GO:0035249 synaptic transmission, glutamatergic;GO:0050804 modulation of chemical synaptic transmission", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q9VDH6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VDM6-1", "uniprot_id": "EI3G2_DROME", "mass": 30526.0, "length": 273, "protein_name": "Eukaryotic translation initiation factor 3 subunit G-2", "gene_name": "eIF3g2", "organism": "Fruit fly", "refseq_name": "eukaryotic translation initiation factor 3 subunit g2", "refseq_ac": "NP_650887", "gene_names_uniprotkb": "eIF3g2; CG10881; eIF3-S4; eIF3gb", "gene_names_refseq": "CG10881; Dmel\\CG10881; cg10881; eIF3-S4; eIF3g2; eIF3gb", "protein_names_uniprotkb": "Eukaryotic translation initiation factor 3 subunit G-2; Eukaryotic translation initiation factor 3 RNA-binding subunit 2; Eukaryotic translation initiation factor 3 subunit 4-2; eIF-3 RNA-binding subunit 2", "protein_names_refseq": "CG10881-PA; eIF3g paralogue b; eIF3g2-PA; eukaryotic translation initiation factor 3 subunit g2", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG10881)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "10731132;12537572", "class_list": "", "function": "RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. This subunit can bind 18S rRNA., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003729 mRNA binding;GO:0003743 translation initiation factor activity", "go_cellular_component": "GO:0016282 eukaryotic 43S preinitiation complex;GO:0033290 eukaryotic 48S preinitiation complex;GO:0005852 eukaryotic translation initiation factor 3 complex", "go_biological_process": "GO:0006413 translational initiation;GO:0001732 formation of cytoplasmic translation initiation complex", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q9VDM6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VDW6-5", "uniprot_id": "DMDA_DROME", "mass": 410414.0, "length": 3598, "protein_name": "Dystrophin, isoforms A/C/F/G/H", "gene_name": "Dys", "organism": "Fruit fly", "refseq_name": "dystrophin, isoform H", "refseq_ac": "NP_001036722", "gene_names_uniprotkb": "Dys; CG34157; det", "gene_names_refseq": "CG17750; CG31175; CG34157; CG7240; CG7243; CG7344; DLP186; DLP1; DLP2; DLP3; DLP; DYS; DmDLP; DmDYS; Dmel\\CG34157; Dp117; Dp186; Dp205; Dys; GI3046716; IDLP; det; dmDLP; dmDp186; dmDys; dys", "protein_names_uniprotkb": "Dystrophin, isoforms A/C/F/G/H; DmDYS; Protein detached", "protein_names_refseq": "CG34157-PH; Dys-PH; Dystrophin-like protein 186; Dystrophin-like protein 1; Dystrophin-like protein 2; Dystrophin-like protein 3; detached; dystrophin Dp186; dystrophin, isoform H; dystrophin", "tax_id": 7227, "disease": "small intestine carcinoid neuroendocrine tumor (Disease Ontology:DOID:0050925); dilated cardiomyopathy 3B (Disease Ontology:DOID:0110461); intellectual disability (Disease Ontology:DOID:1059); Duchenne muscular dystrophy (Disease Ontology:DOID:11723); dilated cardiomyopathy (Disease Ontology:DOID:12930); cognitive disorder (Disease Ontology:DOID:1561); status epilepticus (Disease Ontology:DOID:1824); ovarian cancer (Disease Ontology:DOID:2394); brain edema (Disease Ontology:DOID:4724); congestive heart failure (Disease Ontology:DOID:6000); muscular atrophy (Disease Ontology:DOID:767); retinal degeneration (Disease Ontology:DOID:8466); Becker muscular dystrophy (Disease Ontology:DOID:9883); muscular dystrophy (Disease Ontology:DOID:9884)", "pathway": " (R-DME-114608); (R-DME-446388); (R-DME-9013418); (R-DME-9035034)", "pathway_count": 4, "publication_count": 9, "publication_id_list": "10731132;11018515;11223239;12537572;16399704;17355978;17543506;18093579;18327897", "class_list": "", "function": "Required for the maintenance of appropriate synaptic retrograde communication and the stabilization of muscle cell architecture or physiology. Both det and Dg are required for maintenance of early dpp signaling in the presumptive crossvein. Isoform A is not required to maintain muscle integrity, but plays a role in neuromuscular homeostasis by regulating neurotransmitter release. May play a role in anchoring the cytoskeleton to the plasma membrane., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 14, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q0KI51;Q0KI52;Q0KI53;Q9BK96;Q9BK98;Q9BKA0;Q9GT71;Q9VDW4", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0051015 actin filament binding;GO:0050699 WW domain binding;GO:0008307 structural constituent of muscle", "go_cellular_component": "GO:0016010 dystrophin-associated glycoprotein complex;GO:0005737 cytoplasm;GO:0005856 cytoskeleton;GO:0005886 plasma membrane;GO:0005938 cell cortex", "go_biological_process": "GO:0048172 regulation of short-term neuronal synaptic plasticity;GO:0048790 maintenance of presynaptic active zone structure;GO:0007274 neuromuscular synaptic transmission;GO:0046716 muscle cell cellular homeostasis;GO:0030036 actin cytoskeleton organization", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "Q9VDW6-5", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VE00-1", "uniprot_id": "C12A4_DROME", "mass": 61777.0, "length": 536, "protein_name": "Probable cytochrome P450 12a4, mitochondrial", "gene_name": "Cyp12a4", "organism": "Fruit fly", "refseq_name": "cytochrome P450 12a4", "refseq_ac": "NP_650783", "gene_names_uniprotkb": "Cyp12a4; CG6042", "gene_names_refseq": "12a4; CG6042; CYP12A4; Cyp12A4; Cyp12a4; Dmel\\CG6042; P450; Rst(Luf); cyp12a4", "protein_names_uniprotkb": "Probable cytochrome P450 12a4, mitochondrial; 1.14.-.-; CYPXIIA4", "protein_names_refseq": "CG6042-PA; Cyp12a4-PA; cytochrome P450 12a4; cytochrome P450", "tax_id": 7227, "disease": "colorectal adenoma (Disease Ontology:DOID:0050860); colorectal adenocarcinoma (Disease Ontology:DOID:0050861); oral squamous cell carcinoma (Disease Ontology:DOID:0050866); infantile hypercalcemia 1 (Disease Ontology:DOID:0061136); metabolic dysfunction-associated steatohepatitis (Disease Ontology:DOID:0080547); childhood-onset asthma (Disease Ontology:DOID:0080815); vitamin D-dependent rickets type 1A (Disease Ontology:DOID:0080886); pre-eclampsia (Disease Ontology:DOID:10591); rickets (Disease Ontology:DOID:10609); gestational diabetes (Disease Ontology:DOID:11714); lung cancer (Disease Ontology:DOID:1324); extrahepatic cholestasis (Disease Ontology:DOID:13619); alcohol use disorder (Disease Ontology:DOID:1574); rectum cancer (Disease Ontology:DOID:1993); hepatitis B (Disease Ontology:DOID:2043); colon cancer (Disease Ontology:DOID:219); colon adenocarcinoma (Disease Ontology:DOID:234); nephrosis (Disease Ontology:DOID:2527); asthma (Disease Ontology:DOID:2841); pulmonary tuberculosis (Disease Ontology:DOID:2957); acute kidney failure (Disease Ontology:DOID:3021); chronic obstructive pulmonary disease (Disease Ontology:DOID:3083); breast carcinoma (Disease Ontology:DOID:3459); ovary adenocarcinoma (Disease Ontology:DOID:3713); esophagus squamous cell carcinoma (Disease Ontology:DOID:3748); lung carcinoma (Disease Ontology:DOID:3905); lung non-small cell carcinoma (Disease Ontology:DOID:3908); lung adenocarcinoma (Disease Ontology:DOID:3910); cerebrotendinous xanthomatosis (Disease Ontology:DOID:4810); esophagus adenocarcinoma (Disease Ontology:DOID:4914); esophageal cancer (Disease Ontology:DOID:5041); lung small cell carcinoma (Disease Ontology:DOID:5409); ulcerative colitis (Disease Ontology:DOID:8577); Wilson disease (Disease Ontology:DOID:893); colorectal cancer (Disease Ontology:DOID:9256); type 1 diabetes mellitus (Disease Ontology:DOID:9744); obesity (Disease Ontology:DOID:9970)", "pathway": " (dme:Dmel_CG6042)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "10731132;12537569;12537572;16076534;16120680", "class_list": "", "function": "Has a role in resistance to insecticide lufenuron, but no other insecticides., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 37, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "B8A3W5;Q461P8;Q5CAL0;Q6A1J1;Q6A1J2;Q8SZL9", "ec_number_list": "", "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0004497 monooxygenase activity;GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "go_cellular_component": "GO:0005739 mitochondrion;GO:0031966 mitochondrial membrane", "go_biological_process": "GO:0017085 response to insecticide", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q9VE00-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VE50-1", "uniprot_id": "GOSR1_DROME", "mass": 25562.0, "length": 232, "protein_name": "Golgi SNAP receptor complex member 1", "gene_name": "Gos28", "organism": "Fruit fly", "refseq_name": "golgi SNARE, 28 kDa", "refseq_ac": "NP_650739", "gene_names_uniprotkb": "Gos28; CG7700", "gene_names_refseq": "CG7700; Dmel\\CG7700; FSG28; GOS28; Gos28; dGos28; dgos28; gos28", "protein_names_uniprotkb": "Golgi SNAP receptor complex member 1; Probable 28 kDa Golgi SNARE protein", "protein_names_refseq": "CG7700-PA; Gos28-PA; golgi SNARE, 28 kDa", "tax_id": 7227, "disease": "neurodegenerative disease (Disease Ontology:DOID:1289)", "pathway": " (dme:Dmel_CG7700); (R-DME-6807878); (R-DME-6811438)", "pathway_count": 3, "publication_count": 3, "publication_id_list": "10731132;12537569;12537572", "class_list": "", "function": "Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q8SWZ4", "ec_number_list": "", "go_molecular_function": "GO:0005484 SNAP receptor activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0016020 membrane;GO:0005797 Golgi medial cisterna;GO:0005801 cis-Golgi network;GO:0031201 SNARE complex", "go_biological_process": "GO:0015031 protein transport;GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0048193 Golgi vesicle transport;GO:0006906 vesicle fusion;GO:0006891 intra-Golgi vesicle-mediated transport", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9VE50-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VE51-1", "uniprot_id": "CPSF3_DROME", "mass": 76826.0, "length": 684, "protein_name": "Cleavage and polyadenylation specificity factor 73", "gene_name": "Cpsf73", "organism": "Fruit fly", "refseq_name": "cleavage and polyadenylation specificity factor 73", "refseq_ac": "NP_650738", "gene_names_uniprotkb": "Cpsf73; CG7698", "gene_names_refseq": "CG7698; CPSF-73; CPSF73; Cpsf73; Dmel\\CG7698; cpsf-73; dCPSF-73", "protein_names_uniprotkb": "Cleavage and polyadenylation specificity factor 73; 3.1.27.-", "protein_names_refseq": "CG7698-PA; Cpsf73-PA; cleavage and polyadenylation specificity factor 73; cleavage and polyadenylation specificity factor, 73kD-subunit", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG7698); (R-DME-159231); (R-DME-73856); (R-DME-77595); (R-DME-9770562)", "pathway_count": 5, "publication_count": 7, "publication_id_list": "10731132;12537569;12537572;18042462;19450530;19854135;21078872", "class_list": "", "function": "Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. Has endonuclease activity and functions as an mRNA 3'-end-processing endonuclease. Required for the cotranscriptional processing of 3'-ends of polyadenylated and histone pre-mRNA., [UniProtKB, UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.3.2.-;2.7.7.19;2.7.7.6;3.1.3.16;3.6.4.13;3.4.21.-;3.1.27.-;3.1.-.-", "go_molecular_function": "GO:0003723 RNA binding;GO:0046872 metal ion binding;GO:0004521 RNA endonuclease activity;GO:0004534 5'-3' RNA exonuclease activity", "go_cellular_component": "GO:0005847 mRNA cleavage and polyadenylation specificity factor complex", "go_biological_process": "GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage;GO:0071045 nuclear histone mRNA catabolic process;GO:0180010 co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q9VE51-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VEF0-1", "uniprot_id": "Q9VEF0_DROME", "mass": 50479.0, "length": 430, "protein_name": "Oddjob", "gene_name": "Odj", "organism": "Fruit fly", "refseq_name": "oddjob", "refseq_ac": "NP_650661", "gene_names_uniprotkb": "Odj; CG7357; Dmel\\CG7357; Dmel_CG7357", "gene_names_refseq": "CG7357; Dmel\\CG7357; Odj", "protein_names_uniprotkb": "Oddjob", "protein_names_refseq": "CG7357-PA; Odj-PA; oddjob", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG7357)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0003700 DNA-binding transcription factor activity;GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0000792 heterochromatin", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VEF0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VEQ2-1", "uniprot_id": "Q9VEQ2_DROME", "mass": 32745.0, "length": 282, "protein_name": "ER membrane protein complex subunit 2", "gene_name": "EMC2B", "organism": "Fruit fly", "refseq_name": "ER membrane protein complex subunit 2B, isoform B", "refseq_ac": "NP_001262651", "gene_names_uniprotkb": "EMC2B; CG3678; Dmel\\CG3678; Dmel_CG3678; RE62710p; emc2B", "gene_names_refseq": "CG3678; Dmel\\CG3678; EMC2B; RE62710p; emc2B", "protein_names_uniprotkb": "ER membrane protein complex subunit 2", "protein_names_refseq": "CG3678-PB; EMC2B-PB; ER membrane protein complex subunit 2B, isoform B; endoplasmic reticulum membrane protein complex 2B", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG3678)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0072546 EMC complex;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0071816 tail-anchored membrane protein insertion into ER membrane;GO:0045050 protein insertion into ER membrane by stop-transfer membrane-anchor sequence", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VEQ2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VES8-1", "uniprot_id": "Q9VES8_DROME", "mass": 32034.0, "length": 278, "protein_name": "ATP synthase mitochondrial F1 complex assembly factor 1", "gene_name": "anon2A5", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": "NP_650565", "gene_names_uniprotkb": "anon2A5; CG10340; Dmel\\CG10340; Dmel_CG10340; anon-EST:fe2A5", "gene_names_refseq": "CG10340; Dmel\\CG10340; anon-EST:fe2A5; anon2A5", "protein_names_uniprotkb": "ATP synthase mitochondrial F1 complex assembly factor 1", "protein_names_refseq": "CG10340-PA; anon-fast-evolving-2A5; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG10340)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0140777 protein-containing complex stabilizing activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0007005 mitochondrion organization;GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VES8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VEU0-1", "uniprot_id": "GR89A_DROME", "mass": 41634.0, "length": 362, "protein_name": "Putative gustatory receptor 89a", "gene_name": "Gr89a", "organism": "Fruit fly", "refseq_name": "gustatory receptor 89a", "refseq_ac": "NP_650555", "gene_names_uniprotkb": "Gr89a; CG14901", "gene_names_refseq": "CG14901; Dmel\\CG14901; GR89a; Gr89a", "protein_names_uniprotkb": "Putative gustatory receptor 89a", "protein_names_refseq": "CG14901-PA; Gr89a-PA; gustatory receptor 89a", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG14901)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "10731132;12537572", "class_list": "", "function": "Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0015276 ligand-gated monoatomic ion channel activity;GO:0008527 taste receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane;GO:0030424 axon;GO:0030425 dendrite;GO:0043025 neuronal cell body", "go_biological_process": "GO:0007165 signal transduction;GO:0034220 monoatomic ion transmembrane transport;GO:0050912 detection of chemical stimulus involved in sensory perception of taste", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q9VEU0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VEU5-1", "uniprot_id": "GCYDB_DROME", "mass": 75882.0, "length": 669, "protein_name": "Soluble guanylate cyclase 89Db", "gene_name": "Gyc89Db", "organism": "Fruit fly", "refseq_name": "guanylyl cyclase at 89Db", "refseq_ac": "NP_650551", "gene_names_uniprotkb": "Gyc89Db; CG14886; Gyc-89Db", "gene_names_refseq": "CG14886; Dmel\\CG14886; Gyc-89Db; Gyc89Db", "protein_names_uniprotkb": "Soluble guanylate cyclase 89Db; 4.6.1.2", "protein_names_refseq": "CG14886-PA; Gyc89Db-PA; guanylyl cyclase at 89Db", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG14886)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "10731132;12537569;12537572;15159437;15485853", "class_list": "", "function": "Heterodimers with Gyc88E are activated in response to changing oxygen concentrations, alerting flies to hypoxic environments. Under normal oxygen concentrations, oxygen binds to the heme group and results in low levels of guanylyl cyclase activity. When exposed to reduced oxygen concentrations, the oxygen dissociates from the heme group resulting in activation of the enzyme., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "4.6.1.2", "go_molecular_function": "GO:0004383 guanylate cyclase activity;GO:0005525 GTP binding;GO:0019899 enzyme binding;GO:0046872 metal ion binding;GO:0046982 protein heterodimerization activity", "go_cellular_component": "GO:0008074 guanylate cyclase complex, soluble", "go_biological_process": "GO:0001666 response to hypoxia;GO:0000302 response to reactive oxygen species;GO:0055093 response to hyperoxia;GO:0038060 nitric oxide-cGMP-mediated signaling;GO:0070482 response to oxygen levels", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q9VEU5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VF59-1", "uniprot_id": "B9D1_DROME", "mass": 26866.0, "length": 241, "protein_name": "B9 domain-containing protein 1", "gene_name": "B9d1", "organism": "Fruit fly", "refseq_name": "B9d1", "refseq_ac": "NP_650470", "gene_names_uniprotkb": "B9d1; CG14870", "gene_names_refseq": "B9D1; B9d1; CG14870; Dmel\\CG14870", "protein_names_uniprotkb": "B9 domain-containing protein 1; MKS1-related protein 1", "protein_names_refseq": "B9d1-PA; B9d1; CG14870-PA", "tax_id": 7227, "disease": "Meckel syndrome (Disease Ontology:DOID:0050778); ciliopathy (Disease Ontology:DOID:0060340); Joubert syndrome 27 (Disease Ontology:DOID:0110996); nephronophthisis (Disease Ontology:DOID:12712)", "pathway": " (dme:Dmel_CG14870)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "10731132;12537572;22508513;25447994;27577095;27646273;30013109", "class_list": "", "function": "Probable component of the tectonic-like complex (also named MKS complex), a complex localized at the transition zone of primary cilia (PubMed:27577095, PubMed:27646273). Required for ciliary structure and function (PubMed:27577095)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0036038 MKS complex;GO:0035869 ciliary transition zone", "go_biological_process": "GO:0060271 cilium assembly;GO:1905349 ciliary transition zone assembly;GO:1905350 Y-shaped link assembly", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q9VF59-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VF78-1", "uniprot_id": "COG2_DROME", "mass": 81136.0, "length": 710, "protein_name": "Conserved oligomeric Golgi complex subunit 2", "gene_name": "Cog2", "organism": "Fruit fly", "refseq_name": "component of oligomeric golgi complex 2", "refseq_ac": "NP_524366", "gene_names_uniprotkb": "Cog2; CG6177; ldlCp", "gene_names_refseq": "CG6177; Cog2; Dmel\\CG6177; ldl-Cp; ldlCp", "protein_names_uniprotkb": "Conserved oligomeric Golgi complex subunit 2; COG complex subunit 2; Component of oligomeric Golgi complex 2; LdlCp-related protein", "protein_names_refseq": "CG6177-PA; Cog2-PA; component of oligomeric golgi complex 2; ldlCp-related protein", "tax_id": 7227, "disease": "congenital disorder of glycosylation type IIq (Disease Ontology:DOID:0070269)", "pathway": " (dme:Dmel_CG6177); (R-DME-6807878); (R-DME-6811438); (R-DME-6811440)", "pathway_count": 4, "publication_count": 3, "publication_id_list": "10731132;12537569;12537572", "class_list": "", "function": "Required for normal Golgi morphology and function., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q8SZC5;Q9XZ52", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0017119 Golgi transport complex", "go_biological_process": "GO:0015031 protein transport;GO:0007030 Golgi organization;GO:0000301 retrograde transport, vesicle recycling within Golgi;GO:0006891 intra-Golgi vesicle-mediated transport;GO:0007290 spermatid nucleus elongation", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9VF78-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VF87-1", "uniprot_id": "CYFIP_DROME", "mass": 149261.0, "length": 1291, "protein_name": "Cytoplasmic FMR1-interacting protein", "gene_name": "Cyfip", "organism": "Fruit fly", "refseq_name": "cytoplasmic FMR1 interacting protein", "refseq_ac": "NP_650447", "gene_names_uniprotkb": "Cyfip; CG4931; Sra-1", "gene_names_refseq": "CG4931; CYFIP1/2; CYFIP1; CYFIP; Cyfip; DSra-1; Dmel\\CG4931; PIR121/Sra-1; PIR121; Sra-1/CYFIP; Sra-1; Sra1/PIR121; Sra1; Sra; cyfip; dCYFIP1; dCYFIP; dCyfip; dSra; sra-1; sra1", "protein_names_uniprotkb": "Cytoplasmic FMR1-interacting protein; Specifically Rac1-associated protein 1", "protein_names_refseq": "CG4931-PA; Cyfip-PA; cytoplasmic FMR1 interacting protein; specifically Rac1-associated protein 1; specifically, Rac-1 associated protein 1", "tax_id": 7227, "disease": "autism spectrum disorder (Disease Ontology:DOID:0060041); chromosome 15q11.2 deletion syndrome (Disease Ontology:DOID:0060393); developmental and epileptic encephalopathy 65 (Disease Ontology:DOID:0080430); Schaaf-Yang syndrome (Disease Ontology:DOID:0111715); temporal lobe epilepsy (Disease Ontology:DOID:3328); schizophrenia (Disease Ontology:DOID:5419)", "pathway": " (dme:Dmel_CG4931); (R-DME-2029482); (R-DME-4420097); (R-DME-5663213); (R-DME-6798695); (R-DME-9013149); (R-DME-9013423)", "pathway_count": 7, "publication_count": 9, "publication_id_list": "10731132;11438699;12537569;12537572;12818175;14588242;15269173;15385157;32200800", "class_list": "", "function": "Plays a role in guidance and morphology of central and peripheral axons and in synaptic morphology. Also required for formation of cell membrane protrusions and for bristle development (PubMed:12818175, PubMed:14588242, PubMed:15269173, PubMed:15385157). Plays a role in regulating mitochondrial activity, energy metabolism and membrane potential which maintains normal gamma-aminobutyric acid (GABA) signaling and ensures normal social behavior (PubMed:32200800)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 6, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q6NP16;Q8MR06", "ec_number_list": "", "go_molecular_function": "GO:0031267 small GTPase binding;GO:0000340 RNA 7-methylguanosine cap binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0045177 apical part of cell;GO:0045202 synapse;GO:0031209 SCAR complex;GO:0043005 neuron projection", "go_biological_process": "GO:0006417 regulation of translation;GO:0000902 cell morphogenesis;GO:0033627 cell adhesion mediated by integrin;GO:0008360 regulation of cell shape;GO:0030866 cortical actin cytoskeleton organization", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "Q9VF87-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VFH6-1", "uniprot_id": "CEP78_DROME", "mass": 92782.0, "length": 818, "protein_name": "Protein Cep78 homolog", "gene_name": "CG7886", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": "NP_650378", "gene_names_uniprotkb": "CG7886", "gene_names_refseq": "CG7886; Dmel\\CG7886; anon-WO0140519.200", "protein_names_uniprotkb": "Protein Cep78 homolog", "protein_names_refseq": "CG7886-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG7886)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "10731132;12537569;12537572", "class_list": "", "function": "May play a role in cilium biogenesis., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q8MZ87", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005813 centrosome;GO:0005814 centriole;GO:0036064 ciliary basal body", "go_biological_process": "GO:0044782 cilium organization", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9VFH6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VFJ0-1", "uniprot_id": "CA131_DROME", "mass": 56534.0, "length": 492, "protein_name": "Probable cytochrome P450 313a1", "gene_name": "Cyp313a1", "organism": "Fruit fly", "refseq_name": "cytochrome P450 313a1", "refseq_ac": "NP_650368", "gene_names_uniprotkb": "Cyp313a1; CG3360", "gene_names_refseq": "313a1p; 313a1; CG3360; CYP313a1; Cyp313A1; Cyp313a1p; Cyp313a1; Cyp313a; Dmel\\CG3360", "protein_names_uniprotkb": "Probable cytochrome P450 313a1; 1.14.-.-; CYPCCCXIIIA1", "protein_names_refseq": "CG3360-PA; Cyp313a1-PA; cytochrome P450 313a1", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG3360)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "10731132;12537572", "class_list": "", "function": "May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0004497 monooxygenase activity;GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q9VFJ0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VFP1-1", "uniprot_id": "CP6D5_DROME", "mass": 57384.0, "length": 508, "protein_name": "Probable cytochrome P450 6d5", "gene_name": "Cyp6d5", "organism": "Fruit fly", "refseq_name": "cytochrome P450 6d5", "refseq_ac": "NP_650327", "gene_names_uniprotkb": "Cyp6d5; CG3050", "gene_names_refseq": "6d5; CG3050; CYP6D5; CYP6d5; Cyp6D5; Cyp6d5; Dmel\\CG3050; cyp6d5", "protein_names_uniprotkb": "Probable cytochrome P450 6d5; 1.14.-.-; CYPVID5", "protein_names_refseq": "CG3050-PA; Cyp6d5-PA; cytochrome P450 6d5; cytochrome P450", "tax_id": 7227, "disease": "alcohol dependence (Disease Ontology:DOID:0050741); alcohol-associated liver disease (Disease Ontology:DOID:0070658); prostate cancer (Disease Ontology:DOID:10283); Alzheimer's disease (Disease Ontology:DOID:10652); cholestasis (Disease Ontology:DOID:13580); depressive disorder (Disease Ontology:DOID:1596); anxiety disorder (Disease Ontology:DOID:2030); familial Mediterranean fever (Disease Ontology:DOID:2987); liver cirrhosis (Disease Ontology:DOID:5082); end stage renal disease (Disease Ontology:DOID:783)", "pathway": " (dme:Dmel_CG3050)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "10731132;12537569;12537572", "class_list": "", "function": "May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 10, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0004497 monooxygenase activity;GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9VFP1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VFR0-1", "uniprot_id": "BCCIP_DROME", "mass": 33429.0, "length": 297, "protein_name": "Protein BCCIP homolog", "gene_name": "CG9286", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": "NP_650317", "gene_names_uniprotkb": "CG9286", "gene_names_refseq": "CG9286; Dmel\\CG9286", "protein_names_uniprotkb": "Protein BCCIP homolog", "protein_names_refseq": "CG9286-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG9286)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "10731132;12537569;12537572", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q8T9H9", "ec_number_list": "", "go_molecular_function": "GO:0019887 protein kinase regulator activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9VFR0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VFR1-1", "uniprot_id": "ABITM_DROME", "mass": 23831.0, "length": 214, "protein_name": "Protein Abitram", "gene_name": "abitram", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": "NP_650316", "gene_names_uniprotkb": "abitram; CG9288", "gene_names_refseq": "CG9288; Dmel\\CG9288; Dromel_CG9288_FBtr0082829_pyruvatekinasedomain_mORF", "protein_names_uniprotkb": "Protein Abitram; Actin-binding transcription modulator", "protein_names_refseq": "CG9288-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG9288)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "10731132;12537569;12537572", "class_list": "", "function": "May regulate actin polymerization., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003785 actin monomer binding;GO:0051015 actin filament binding", "go_cellular_component": "GO:0005634 nucleus;GO:0030027 lamellipodium;GO:0030425 dendrite;GO:0032433 filopodium tip", "go_biological_process": "GO:0048813 dendrite morphogenesis;GO:0051489 regulation of filopodium assembly;GO:0030833 regulation of actin filament polymerization", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9VFR1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VG17-1", "uniprot_id": "CP304_DROME", "mass": 58790.0, "length": 510, "protein_name": "Probable cytochrome P450 304a1", "gene_name": "Cyp304a1", "organism": "Fruit fly", "refseq_name": "cytochrome P450 304a1", "refseq_ac": "NP_731751", "gene_names_uniprotkb": "Cyp304a1; CG7241", "gene_names_refseq": "304a1; BcDNA:LP06355; CG7241; CYP304A1-Dm; CYP304A1; CYP304a1; Cyp304A1; Cyp304a1; Dmel\\CG7241", "protein_names_uniprotkb": "Probable cytochrome P450 304a1; 1.14.-.-; CYPCCCIVA1", "protein_names_refseq": "CG7241-PA; Cyp304a1-PA; cytochrome P450 304a1; cytochrome P450", "tax_id": 7227, "disease": "invasive aspergillosis (Disease Ontology:DOID:0050073); Keshan disease (Disease Ontology:DOID:0050083); alcohol dependence (Disease Ontology:DOID:0050741); hepatocellular adenoma (Disease Ontology:DOID:0050868); alcohol-associated liver disease (Disease Ontology:DOID:0070658); metabolic dysfunction-associated steatotic liver disease (Disease Ontology:DOID:0080208); warfarin resistance (Disease Ontology:DOID:0080665); renal hypertension (Disease Ontology:DOID:1073); hypertension (Disease Ontology:DOID:10763); sickle cell anemia (Disease Ontology:DOID:10923); urinary bladder cancer (Disease Ontology:DOID:11054); familial hyperlipidemia (Disease Ontology:DOID:1168); hypertrophic cardiomyopathy (Disease Ontology:DOID:11984); dilated cardiomyopathy (Disease Ontology:DOID:12930); eosinophilic esophagitis (Disease Ontology:DOID:13922); Plasmodium falciparum malaria (Disease Ontology:DOID:14067); alcohol use disorder (Disease Ontology:DOID:1574); depressive disorder (Disease Ontology:DOID:1596); breast cancer (Disease Ontology:DOID:1612); drug-induced hepatitis (Disease Ontology:DOID:2044); colon cancer (Disease Ontology:DOID:219); acute kidney failure (Disease Ontology:DOID:3021); middle cerebral artery infarction (Disease Ontology:DOID:3525); tuberculosis (Disease Ontology:DOID:399); liver disease (Disease Ontology:DOID:409); hyperglycemia (Disease Ontology:DOID:4195); multiple chemical sensitivity (Disease Ontology:DOID:4661); head and neck squamous cell carcinoma (Disease Ontology:DOID:5520); hepatocellular carcinoma (Disease Ontology:DOID:684); peptic ulcer disease (Disease Ontology:DOID:750); end stage renal disease (Disease Ontology:DOID:783); diabetes mellitus (Disease Ontology:DOID:9351); type 2 diabetes mellitus (Disease Ontology:DOID:9352); steatotic liver disease (Disease Ontology:DOID:9452); multiple myeloma (Disease Ontology:DOID:9538); obesity (Disease Ontology:DOID:9970); heroin dependence (Disease Ontology:DOID:9976); hypoglycemia (Disease Ontology:DOID:9993)", "pathway": " (dme:Dmel_CG7241)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "10731132;12537569;12537572", "class_list": "", "function": "May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 38, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0004497 monooxygenase activity;GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9VG17-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VG38-1", "uniprot_id": "Q9VG38_DROME", "mass": 52788.0, "length": 468, "protein_name": "Suppressor of fused homolog", "gene_name": "Su(fu)", "organism": "Fruit fly", "refseq_name": "suppressor of fused", "refseq_ac": "NP_536750", "gene_names_uniprotkb": "Su(fu); CG6054; Dmel\\CG6054; Dmel_CG6054; SU(FU); SUFU; Su(Fu); SuFu; Sufu; d Sufu; dSufu; su(fu); sufu", "gene_names_refseq": "CG6054; Dmel\\CG6054; SU(FU); SUFU; Su(Fu); Su(fu); SuFu; Sufu; d Sufu; dSufu; su(fu); sufu", "protein_names_uniprotkb": "Suppressor of fused homolog", "protein_names_refseq": "CG6054-PA; Su(fu)-PA; suppressor of fused", "tax_id": 7227, "disease": "medulloblastoma (Disease Ontology:DOID:0050902); pre-malignant neoplasm (Disease Ontology:DOID:0060071); nevoid basal cell carcinoma syndrome 2 (Disease Ontology:DOID:0070366); Joubert syndrome 32 (Disease Ontology:DOID:0080278); nevoid basal cell carcinoma syndrome (Disease Ontology:DOID:2512); brain glioblastoma multiforme (Disease Ontology:DOID:3073); familial meningioma (Disease Ontology:DOID:4586)", "pathway": " (dme:Dmel_CG6054); (R-DME-5610780); (R-DME-5610785); (R-DME-5610787); (R-DME-5632684)", "pathway_count": 5, "publication_count": 12, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;24217340;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 7, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding;GO:0008139 nuclear localization sequence binding;GO:0140297 DNA-binding transcription factor binding;GO:0140313 molecular sequestering activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0032991 protein-containing complex", "go_biological_process": "GO:0045879 negative regulation of smoothened signaling pathway", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "Q9VG38-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VG55-1", "uniprot_id": "HUGIN_DROME", "mass": 20623.0, "length": 191, "protein_name": "Protein hugin", "gene_name": "Hug", "organism": "Fruit fly", "refseq_name": "hugin", "refseq_ac": "NP_524329", "gene_names_uniprotkb": "Hug; CG6371", "gene_names_refseq": "CG6371; Dmel\\CG6371; Drm-MT2; Drm-PK-2; HUGgamma; HUG; Hug-PK; Hug-gamma; Hugin PK; Hugin-PK-2; Hug; PK-2; hug gamma; hug-1; hug-2; hug-PK; hug-gamma; huggamma; hugg; huginPK; hugin; hug; pyrokinin/PBAN-like", "protein_names_uniprotkb": "Protein hugin; Drm-MT2; Drm-PK-2; MT-2; Myotrophin-2; Pyrokinin-2", "protein_names_refseq": "CG6371-PA; Hug-PA; Hugin-gamma; Hugin-pyrokinin; SVPFKPRLamide; hugin gamma; hugin; pyrokinin-2", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG6371)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "10731132;12171930;12204246;12537569;12537572;14690519", "class_list": "", "function": "Probably has a role in larval molting., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005179 hormone activity;GO:0008255 ecdysis-triggering hormone activity;GO:0016084 myostimulatory hormone activity;GO:0160041 neuropeptide activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0005615 extracellular space", "go_biological_process": "GO:0007218 neuropeptide signaling pathway;GO:0018990 ecdysis, chitin-based cuticle;GO:0030536 larval feeding behavior", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q9VG55-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VG73-1", "uniprot_id": "ILF2_DROME", "mass": 43657.0, "length": 396, "protein_name": "Interleukin enhancer-binding factor 2 homolog", "gene_name": "CG5641", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": "NP_650196", "gene_names_uniprotkb": "CG5641", "gene_names_refseq": "CG5641; Dmel\\CG5641", "protein_names_uniprotkb": "Interleukin enhancer-binding factor 2 homolog", "protein_names_refseq": "CG5641-PA; interleukin enhancer binding factor; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG5641); (R-DME-6798695); (R-DME-9833482)", "pathway_count": 3, "publication_count": 3, "publication_id_list": "10731132;12537569;12537572", "class_list": "", "function": "May regulate transcription of undefined genes., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0003725 double-stranded RNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005730 nucleolus;GO:0071013 catalytic step 2 spliceosome;GO:0071011 precatalytic spliceosome", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045893 positive regulation of DNA-templated transcription;GO:0000398 mRNA splicing, via spliceosome", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9VG73-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VG92-1", "uniprot_id": "Q9VG92_DROME", "mass": 24179.0, "length": 212, "protein_name": "1.11.1.9; 2.5.1.18; Glutathione S transferase D8", "gene_name": "GstD8", "organism": "Fruit fly", "refseq_name": "glutathione S transferase D8", "refseq_ac": "NP_524916", "gene_names_uniprotkb": "GstD8; CG4421; DmGST27; DmGSTD8; Dmel\\CG4421; Dmel_CG4421; GST D27; GSTD8; GST; GstD27; Gst; gstD27; gstD8; gstd8; gst", "gene_names_refseq": "CG4421; DmGST27; DmGSTD8; Dmel\\CG4421; GST D27; GSTD8; GST; GstD27; GstD8; Gst; gstD27; gstD8; gstd8; gst", "protein_names_uniprotkb": "1.11.1.9; 2.5.1.18; Glutathione S transferase D8", "protein_names_refseq": "CG4421-PA; Glutathione-S-transferase; GstD8-PA; glutathione S transferase D27; glutathione S transferase D8", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG4421)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004364 glutathione transferase activity;GO:0004602 glutathione peroxidase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0006749 glutathione metabolic process", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VG92-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VG95-1", "uniprot_id": "GSTD5_DROME", "mass": 24713.0, "length": 216, "protein_name": "Glutathione S-transferase D5", "gene_name": "GstD5", "organism": "Fruit fly", "refseq_name": "glutathione S transferase D5", "refseq_ac": "NP_524914", "gene_names_uniprotkb": "GstD5; CG12242; GSTD5-5; gstD24", "gene_names_refseq": "CG12242; D5; DmGST24; DmGSTD5; Dmel\\CG12242; GSTD5; GSTd5; GST; Gst D5; GstD24; GstD5; Gst; dGSTT4; gstD24; gstD5; gstd5; gst", "protein_names_uniprotkb": "Glutathione S-transferase D5; 2.5.1.18", "protein_names_refseq": "CG12242-PA; GstD5-PA; glutathione S transferase D24; glutathione S transferase D5; glutathione-S-transferase D5", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG12242)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "10731132;12537572;22082028;7683659", "class_list": "", "function": "Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles (PubMed:22082028). May be involved in detoxification (PubMed:22082028)., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9TX92", "ec_number_list": "2.5.1.18;4.5.1.1;5.2.1.2", "go_molecular_function": "GO:0004364 glutathione transferase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0009636 response to toxic substance;GO:0006749 glutathione metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q9VG95-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VG98-1", "uniprot_id": "GSTD2_DROME", "mass": 24535.0, "length": 215, "protein_name": "Glutathione S-transferase D2", "gene_name": "GstD2", "organism": "Fruit fly", "refseq_name": "glutathione S transferase D2", "refseq_ac": "NP_524912", "gene_names_uniprotkb": "GstD2; CG4181; GSTD2-2; gstD21", "gene_names_refseq": "CG4181; DmGST21; DmGSTD2; Dmel\\CG4181; GST D2; GST-D2; GSTD2; GSTd2; GST; Gst D2; GstD21; GstD2; Gstd21; Gst; gst D21; gstD21; gstD2; gstd21; gstd2; gst", "protein_names_uniprotkb": "Glutathione S-transferase D2; 2.5.1.18", "protein_names_refseq": "CG4181-PA; GstD2-PA; glutathione S transferase D21; glutathione S transferase D2; glutathione-S-transferase D2", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG4181)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "10731132;12537572;22082028;7683659", "class_list": "", "function": "Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles (PubMed:22082028). May be involved in detoxification (PubMed:22082028)., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9TX91", "ec_number_list": "2.5.1.18;4.5.1.1;5.2.1.2", "go_molecular_function": "GO:0004364 glutathione transferase activity;GO:0004602 glutathione peroxidase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0006749 glutathione metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q9VG98-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VGB4-1", "uniprot_id": "CP132_DROME", "mass": 56651.0, "length": 493, "protein_name": "Probable cytochrome P450 313a2", "gene_name": "Cyp313a2", "organism": "Fruit fly", "refseq_name": "cytochrome P450 313a2", "refseq_ac": "NP_650169", "gene_names_uniprotkb": "Cyp313a2; CG10094", "gene_names_refseq": "313a2; CG10094; CYP313A2; Cyp313A2; Cyp313a2; Dmel\\CG10094", "protein_names_uniprotkb": "Probable cytochrome P450 313a2; 1.14.-.-; CYPCCCXIIIA2", "protein_names_refseq": "CG10094-PB; Cyp313a2-PB; cytochrome P450 313a2", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG10094)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "10731132;12537572", "class_list": "", "function": "May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0004497 monooxygenase activity;GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q9VGB4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VGB5-1", "uniprot_id": "CP135_DROME", "mass": 55618.0, "length": 487, "protein_name": "Probable cytochrome P450 313a5", "gene_name": "Cyp313a5", "organism": "Fruit fly", "refseq_name": "cytochrome P450 313a5", "refseq_ac": "NP_650168", "gene_names_uniprotkb": "Cyp313a5; CG15807", "gene_names_refseq": "313a5; CG15807; CYP313a5; Cyp313a5; Dmel\\CG15807", "protein_names_uniprotkb": "Probable cytochrome P450 313a5; 1.14.-.-; CYPCCCXIIIA5", "protein_names_refseq": "CG15807-PA; Cyp313a5-PA; cytochrome P450 313a5", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG15807)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "10731132;12537572;18327897", "class_list": "", "function": "May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q4QQD1", "ec_number_list": "", "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0004497 monooxygenase activity;GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9VGB5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VGC1-1", "uniprot_id": "Q9VGC1_DROME", "mass": 45932.0, "length": 421, "protein_name": "Radial spoke binding protein 15", "gene_name": "Rsbp15", "organism": "Fruit fly", "refseq_name": "radial spoke binding protein 15", "refseq_ac": "NP_650164", "gene_names_uniprotkb": "Rsbp15; CG10014; Dmel\\CG10014; Dmel_CG10014; RSBP15; rsbp15", "gene_names_refseq": "CG10014; Dmel\\CG10014; RSBP15; Rsbp15; rsbp15", "protein_names_uniprotkb": "Radial spoke binding protein 15", "protein_names_refseq": "CG10014-PA; Rsbp15-PA; radial spoke binding protein 15", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG10014)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0031514 motile cilium;GO:0036126 sperm flagellum;GO:0070864 sperm individualization complex", "go_biological_process": "GO:0035082 axoneme assembly;GO:0120229 protein localization to motile cilium", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VGC1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VGC7-1", "uniprot_id": "EI3D2_DROME", "mass": 62749.0, "length": 551, "protein_name": "Eukaryotic translation initiation factor 3 subunit D-2", "gene_name": "eIF3d2", "organism": "Fruit fly", "refseq_name": "eukaryotic translation initiation factor 3 subunit d2", "refseq_ac": "NP_731675", "gene_names_uniprotkb": "eIF3d2; CG4810; eIF3-S7-2", "gene_names_refseq": "149735_at; CG4810; Dmel\\CG4810; eIF3-S7; eIF3d2", "protein_names_uniprotkb": "Eukaryotic translation initiation factor 3 subunit D-2; Eukaryotic translation initiation factor 3 subunit 7-2; eIF3d-2", "protein_names_refseq": "CG4810-PA; eIF3d2-PA; eukaryotic translation initiation factor 3 subunit d2", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG4810)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "10731132;12537569;12537572", "class_list": "", "function": "mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. In the eIF-3 complex, eif3d specifically recognizes and binds the 7-methylguanosine cap of a subset of mRNAs., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003743 translation initiation factor activity;GO:0098808 mRNA cap binding", "go_cellular_component": "GO:0016282 eukaryotic 43S preinitiation complex;GO:0033290 eukaryotic 48S preinitiation complex;GO:0005852 eukaryotic translation initiation factor 3 complex", "go_biological_process": "GO:0006413 translational initiation;GO:0006446 regulation of translational initiation;GO:0001732 formation of cytoplasmic translation initiation complex;GO:0002191 cap-dependent translational initiation", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9VGC7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VGJ5-1", "uniprot_id": "FER3_DROME", "mass": 22124.0, "length": 195, "protein_name": "Protein Fer3", "gene_name": "fer3", "organism": "Fruit fly", "refseq_name": "48 related 3", "refseq_ac": "NP_524322", "gene_names_uniprotkb": "fer3; CG6913; Nato3; Ntwist", "gene_names_refseq": "BcDNA:LD04689; CG6913; Dmel\\CG6913; Dnato3; Fer3; bHLHa32; nato3", "protein_names_uniprotkb": "Protein Fer3; Basic helix-loop-helix protein N-twist; Nephew of atonal 3; Neuronal twist", "protein_names_refseq": "48 related 3; CG6913-PA; Fer3-PA; N-twist; nephew of atonal 3; ntwist", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG6913)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "10731132;10973473;11472856;12217327;12537569;12537572;16951084", "class_list": "", "function": "Transcription factor that binds to the E-box and functions as inhibitor of transcription. DNA binding requires dimerization with an E protein. Inhibits transcription activation by ASCL1/MASH1 by sequestering E proteins (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0AQE5", "ec_number_list": "", "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0046983 protein dimerization activity;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0006355 regulation of DNA-templated transcription;GO:0045892 negative regulation of DNA-templated transcription;GO:0032502 developmental process", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q9VGJ5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VGN7-1", "uniprot_id": "EXD2_DROME", "mass": 66867.0, "length": 583, "protein_name": "Exonuclease 3'-5' domain-containing protein 2", "gene_name": "Exd2", "organism": "Fruit fly", "refseq_name": "exonuclease 3'-5' domain-containing 2, isoform B", "refseq_ac": "NP_001247048", "gene_names_uniprotkb": "Exd2; CG6744", "gene_names_refseq": "CG6744; Dmel\\CG6744; EXD2; Exd2; dEXD2", "protein_names_uniprotkb": "Exonuclease 3'-5' domain-containing protein 2; 3.1.13.-; dEXD2", "protein_names_refseq": "CG6744-PB; Exd2-PB; exonuclease 3'-5' domain-containing 2, isoform B", "tax_id": 7227, "disease": "Werner syndrome (Disease Ontology:DOID:5688)", "pathway": " (dme:Dmel_CG6744)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "10731132;12537569;12537572;18056975;29335528", "class_list": "", "function": "3'-5' exoribonuclease required for mitochondrial metabolism., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0046872 metal ion binding;GO:0003676 nucleic acid binding;GO:0008408 3'-5' exonuclease activity;GO:0000175 3'-5'-RNA exonuclease activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005759 mitochondrial matrix;GO:0031966 mitochondrial membrane", "go_biological_process": "GO:0016444 somatic cell DNA recombination;GO:1901195 positive regulation of formation of translation preinitiation complex", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q9VGN7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VGQ9-1", "uniprot_id": "DPH3_DROME", "mass": 10115.0, "length": 86, "protein_name": "Diphthamide biosynthesis protein 3", "gene_name": "Dph3", "organism": "Fruit fly", "refseq_name": "diphthamide biosynthesis 3", "refseq_ac": "NP_650057", "gene_names_uniprotkb": "Dph3; CG14701", "gene_names_refseq": "CG14701; Dmel\\CG14701; Dph3; Kti11", "protein_names_uniprotkb": "Diphthamide biosynthesis protein 3", "protein_names_refseq": "CG14701-PA; Dph3-PA; diphthamide biosynthesis 3", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG14701); (R-DME-5358493)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "10731132;12537572", "class_list": "", "function": "Required for the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2. Dph1 and Dph2 transfer a 3-amino-3-carboxypropyl (ACP) group from S-adenosyl-L-methionine (SAM) to a histidine residue, the reaction is assisted by a reduction system comprising Dph3 and a NADH-dependent reductase. Acts as an electron donor to reduce the Fe-S cluster in Dph1-Dph2 keeping the [4Fe-4S] clusters in the active and reduced state. Restores iron to Dph1-Dph2 iron-sulfur clusters which have degraded from [4Fe-4S] to [3Fe-4S] by donating an iron atom to reform [4Fe-4S] clusters, in a manner dependent on the presence of elongation factor 2 and SAM. Associates with the elongator complex and is required for tRNA Wobble base modifications mediated by the elongator complex. The elongator complex is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s 2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q4QPS1", "ec_number_list": "", "go_molecular_function": "GO:0005506 iron ion binding;GO:0016491 oxidoreductase activity;GO:0008198 ferrous iron binding;GO:0034986 iron chaperone activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol", "go_biological_process": "GO:0017183 protein histidyl modification to diphthamide;GO:0002926 tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q9VGQ9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VGZ1-1", "uniprot_id": "CK5P1_DROME", "mass": 65829.0, "length": 583, "protein_name": "CDK5RAP1-like protein", "gene_name": "CG6345", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": "NP_650002", "gene_names_uniprotkb": "CG6345", "gene_names_refseq": "149631_at; CG6345; Dmel\\CG6345", "protein_names_uniprotkb": "CDK5RAP1-like protein", "protein_names_refseq": "CG6345-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG6345)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "10731132;12537569;12537572", "class_list": "", "function": "Potential regulator of CDK5 activity., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0046872 metal ion binding;GO:0051539 4 iron, 4 sulfur cluster binding;GO:0035597 tRNA-2-methylthio-N(6)-dimethylallyladenosine(37) synthase activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix;GO:0005829 cytosol", "go_biological_process": "GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity;GO:0009451 RNA modification;GO:0070900 mitochondrial tRNA modification", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9VGZ1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VGZ2-1", "uniprot_id": "Q9VGZ2_DROME", "mass": 25738.0, "length": 233, "protein_name": "Rrp46", "gene_name": "Rrp46", "organism": "Fruit fly", "refseq_name": "Rrp46", "refseq_ac": "NP_650001", "gene_names_uniprotkb": "Rrp46; CG4043; Dmel\\CG4043; Dmel_CG4043; dRrp46; rrp46", "gene_names_refseq": "CG4043; Dmel\\CG4043; Rrp46; dRrp46; rrp46", "protein_names_uniprotkb": "Rrp46", "protein_names_refseq": "CG4043-PA; Rrp46-PA; Rrp46", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG4043); (R-DME-429958); (R-DME-450385); (R-DME-450513); (R-DME-6791226); (R-DME-9930044)", "pathway_count": 6, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0000176 nuclear exosome (RNase complex);GO:0000177 cytoplasmic exosome (RNase complex)", "go_biological_process": "GO:0071028 nuclear mRNA surveillance;GO:0010468 regulation of gene expression;GO:0006364 rRNA processing;GO:0016075 rRNA catabolic process;GO:0006401 RNA catabolic process", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VGZ2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VGZ5-1", "uniprot_id": "CWO_DROME", "mass": 75106.0, "length": 698, "protein_name": "Transcription factor cwo", "gene_name": "cwo", "organism": "Fruit fly", "refseq_name": "clockwork orange, isoform A", "refseq_ac": "NP_524775", "gene_names_uniprotkb": "cwo; CG17100", "gene_names_refseq": "AAF24476.1; CG17100; CWO; Cwo; Dmel\\CG17100; GM05287; bHLHe49; cwo; dcwo; mel_cwo", "protein_names_uniprotkb": "Transcription factor cwo; Protein clockwork orange", "protein_names_refseq": "CG17100-PA; CLOCKWORK ORANGE; clockwork orange, isoform A; clockworkorange; cwo-PA; stich", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG17100); (R-DME-432408)", "pathway_count": 2, "publication_count": 8, "publication_id_list": "10731132;11102367;12537572;17555964;17578907;17578908;18375860;27814361", "class_list": "", "function": "Plays a role in the regulation of circadian rhythms (PubMed:17555964, PubMed:17578907, PubMed:17578908, PubMed:27814361). Transcriptional repressor which inhibits Clock-mediated transcriptional activation by binding to E boxes in the promoters of Clock target genes and repressing their transcription (PubMed:17555964, PubMed:17578907, PubMed:17578908, PubMed:27814361). E box binding activity is time-dependent with higher binding activity seen in the early morning (zeitgeber time 2) than early evening (zeitgeber time 14) and is dependent on the presence of the circadian protein per (PubMed:27814361). It is likely that per binds to Clock-cycle heterodimers, reducing their affinity for E box binding and allowing cwo to bind instead (PubMed:27814361). Negatively regulates its own expression (PubMed:17578908, PubMed:18375860)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "C8VV96;Q9U450", "ec_number_list": "", "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0046983 protein dimerization activity;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0007219 Notch signaling pathway;GO:0006355 regulation of DNA-templated transcription;GO:0007623 circadian rhythm", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q9VGZ5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VH36-1", "uniprot_id": "CRBN_DROME", "mass": 66453.0, "length": 585, "protein_name": "Protein cereblon", "gene_name": "ohgt", "organism": "Fruit fly", "refseq_name": "ohgata", "refseq_ac": "NP_649973", "gene_names_uniprotkb": "ohgt; CG3925; crbn", "gene_names_refseq": "CG3925; Crbn; Dmel\\CG3925; ohgt", "protein_names_uniprotkb": "Protein cereblon; Protein ohgata", "protein_names_refseq": "CG3925-PA; ohgata; ohgt-PA", "tax_id": 7227, "disease": "autosomal recessive intellectual developmental disorder (Disease Ontology:DOID:0060308); autosomal recessive intellectual developmental disorder 2 (Disease Ontology:DOID:0081178)", "pathway": " (dme:Dmel_CG3925)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "10731132;12537569;12537572;27702999;29530986", "class_list": "", "function": "Substrate recognition component of a DCX (DDB1-CUL4-X-box) E3 protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins (Probable). Has an essential role in mediating growth by negatively regulating insulin signaling (PubMed:27702999). It also has a role in maintaining presynaptic function in the neuromuscular junction synapses of third-instar larvae (PubMed:29530986)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9VH35", "ec_number_list": "", "go_molecular_function": "GO:0046872 metal ion binding", "go_cellular_component": "GO:0031464 Cul4A-RING E3 ubiquitin ligase complex;GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0016567 protein ubiquitination;GO:0030177 positive regulation of Wnt signaling pathway;GO:1900075 positive regulation of neuromuscular synaptic transmission", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q9VH36-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VH45-1", "uniprot_id": "Q9VH45_DROME", "mass": 19063.0, "length": 173, "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG5359", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform B", "refseq_ac": "NP_001163579", "gene_names_uniprotkb": "Dmel\\CG5359; BcDNA:RE37471; CG5359; Dmel_CG5359", "gene_names_refseq": "BcDNA:RE37471; CG5359; Dmel\\CG5359", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "CG5359-PB; uncharacterized protein, isoform B", "tax_id": 7227, "disease": "asphyxiating thoracic dystrophy (Disease Ontology:DOID:0050592); ciliopathy (Disease Ontology:DOID:0060340); spermatogenic failure (Disease Ontology:DOID:0111910)", "pathway": " (dme:Dmel_CG5359)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0016787 hydrolase activity;GO:0045505 dynein intermediate chain binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005868 cytoplasmic dynein complex;GO:0030286 dynein complex", "go_biological_process": "GO:0007018 microtubule-based movement", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VH45-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VH48-1", "uniprot_id": "CARM1_DROME", "mass": 59728.0, "length": 530, "protein_name": "Probable histone-arginine methyltransferase CARMER", "gene_name": "Art4", "organism": "Fruit fly", "refseq_name": "arginine methyltransferase 4, isoform B", "refseq_ac": "NP_001262445", "gene_names_uniprotkb": "Art4; CG5358; Carmer", "gene_names_refseq": "Art4; CARM1; CG5358; DART4; Dart4; Dmel\\CG5358; PRMT4; dArt 4", "protein_names_uniprotkb": "Probable histone-arginine methyltransferase CARMER; 2.1.1.319; Coactivator arginine methyltransferase for EcR/Usp; DART4; Protein arginine N-methyltransferase 4", "protein_names_refseq": "Art4-PB; CARMER; CG5358-PB; arginie methyl transferase 4; arginine methyl-transferase 4; arginine methyltransferase 4, isoform B; coactivator Arg methyltransferase for Ecr/Usp", "tax_id": 7227, "disease": "hepatocellular adenoma (Disease Ontology:DOID:0050868); estrogen-receptor positive breast cancer (Disease Ontology:DOID:0060075); asthma (Disease Ontology:DOID:2841); hepatocellular carcinoma (Disease Ontology:DOID:684); prostate carcinoma in situ (Disease Ontology:DOID:8634)", "pathway": " (dme:Dmel_CG5358); (R-DME-400206); (R-DME-9018519); (R-DME-9707564)", "pathway_count": 4, "publication_count": 6, "publication_id_list": "10731132;12537569;12537572;14705965;14976192;17459088", "class_list": "", "function": "Methylates (mono- and asymmetric dimethylation) the guanidino nitrogens of arginyl residues in proteins. May methylate histone H3 at 'Arg-17' and activate transcription via chromatin remodeling. Coordinates ecdysone-mediated expression of cell death genes., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q86NL6", "ec_number_list": "2.3.1.48;3.6.4.13;5.6.2.5;3.5.1.98;2.1.1.319", "go_molecular_function": "GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity;GO:0042054 histone methyltransferase activity;GO:0035241 protein-arginine omega-N monomethyltransferase activity;GO:0070611 histone H3R2 methyltransferase activity;GO:0035642 histone H3R17 methyltransferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0035097 histone methyltransferase complex", "go_biological_process": "GO:0006338 chromatin remodeling;GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0006355 regulation of DNA-templated transcription;GO:0032259 methylation", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q9VH48-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VH58-1", "uniprot_id": "ELOF_DROME", "mass": 29923.0, "length": 257, "protein_name": "Very long chain fatty acid elongase F", "gene_name": "eloF", "organism": "Fruit fly", "refseq_name": "elongase F", "refseq_ac": "NP_649956", "gene_names_uniprotkb": "eloF; CG16905", "gene_names_refseq": "CG16905; Dmel\\CG16905; EloF; eloF", "protein_names_uniprotkb": "Very long chain fatty acid elongase F; 2.3.1.199; Elongation of very long chain fatty acids protein F", "protein_names_refseq": "CG16905-PA; eloF-PA; elongase F; elongase", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG16905); (R-DME-2046105); (R-DME-2046106); (R-DME-75876)", "pathway_count": 4, "publication_count": 3, "publication_id_list": "10731132;12537572;17360514", "class_list": "", "function": "Condensing enzyme that elongates saturated and monounsaturated very long chain fatty acids, to yield products up to 30 carbons in length. May also elongate diunsaturated fatty acids. Important for courtship behavior where it probably has a role in female pheromone biosynthesis., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q0E5H2", "ec_number_list": "2.3.1.199", "go_molecular_function": "GO:0009922 fatty acid elongase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0030148 sphingolipid biosynthetic process;GO:0030497 fatty acid elongation;GO:0034625 fatty acid elongation, monounsaturated fatty acid;GO:0034626 fatty acid elongation, polyunsaturated fatty acid;GO:0019367 fatty acid elongation, saturated fatty acid", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9VH58-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VH78-1", "uniprot_id": "ALG12_DROME", "mass": 76553.0, "length": 678, "protein_name": "Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase", "gene_name": "Alg12", "organism": "Fruit fly", "refseq_name": "Alg12 alpha-1,6-mannosyltransferase", "refseq_ac": "NP_649939", "gene_names_uniprotkb": "Alg12; CG8412", "gene_names_refseq": "Alg12; CG8412; Dmel\\CG8412; dAlg12", "protein_names_uniprotkb": "Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase; 2.4.1.260; Asparagine-linked glycosylation protein 12 homolog; Dolichyl-P-Man:Man(7)GlcNAc(2)-PP-dolichyl-alpha-1,6-mannosyltransferase; Mannosyltransferase ALG12 homolog", "protein_names_refseq": "Alg12 alpha-1,6-mannosyltransferase; Alg12-PA; CG8412-PA", "tax_id": 7227, "disease": "congenital disorder of glycosylation type I (Disease Ontology:DOID:0050570); congenital disorder of glycosylation Ig (Disease Ontology:DOID:0080559)", "pathway": " (dme:Dmel_CG8412); (R-DME-446193)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "10731132;12537569;12537572", "class_list": "", "function": "Mannosyltransferase that operates in the biosynthetic pathway of dolichol-linked oligosaccharides, the glycan precursors employed in protein asparagine (N)-glycosylation. The assembly of dolichol-linked oligosaccharides begins on the cytosolic side of the endoplasmic reticulum membrane and finishes in its lumen. The sequential addition of sugars to dolichol pyrophosphate produces dolichol-linked oligosaccharides containing fourteen sugars, including two GlcNAcs, nine mannoses and three glucoses. Once assembled, the oligosaccharide is transferred from the lipid to nascent proteins by oligosaccharyltransferases. In the lumen of the endoplasmic reticulum, adds the eighth mannose residue in an alpha-1,6 linkage onto Man(7)GlcNAc(2)-PP-dolichol to produce Man(8)GlcNAc(2)-PP-dolichol., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.4.1.260", "go_molecular_function": "GO:0000009 alpha-1,6-mannosyltransferase activity;GO:0052917 dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006488 dolichol-linked oligosaccharide biosynthetic process;GO:0006487 protein N-linked glycosylation", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9VH78-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VH89-1", "uniprot_id": "DALMA_DROME", "mass": 96513.0, "length": 857, "protein_name": "Protein dalmatian", "gene_name": "dmt", "organism": "Fruit fly", "refseq_name": "dalmatian", "refseq_ac": "NP_524295", "gene_names_uniprotkb": "dmt; CG8374", "gene_names_refseq": "0481/03; CG8374; Dmel\\CG8374; Dmt; anon-WO0118547.317; aul; dmt; s048103", "protein_names_uniprotkb": "Protein dalmatian; Sororin ortholog", "protein_names_refseq": "CG8374-PA; anduril; dalmatian; dalmation; dmt-PA", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG8374)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "10731132;11102367;12537569;12537572;18327897;21111234", "class_list": "", "function": "Regulator of sister chromatid cohesion in mitosis. Probably involved in development of the central nervous system., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q9U449", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0000785 chromatin;GO:0000792 heterochromatin", "go_biological_process": "GO:0043066 negative regulation of apoptotic process;GO:0051301 cell division;GO:0007422 peripheral nervous system development;GO:0071478 cellular response to radiation;GO:0007431 salivary gland development", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q9VH89-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VHG6-1", "uniprot_id": "Q9VHG6_DROME", "mass": 21939.0, "length": 195, "protein_name": "Insulator binding factor 2", "gene_name": "Ibf2", "organism": "Fruit fly", "refseq_name": "insulator binding factor 2", "refseq_ac": "NP_649874", "gene_names_uniprotkb": "Ibf2; CG9740; Dmel\\CG9740; Dmel_CG9740; Ibf", "gene_names_refseq": "CG9740; Dmel\\CG9740; Ibf2; Ibf", "protein_names_uniprotkb": "Insulator binding factor 2", "protein_names_refseq": "CG9740-PA; Ibf2-PA; insulator binding factor 2", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG9740)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0043035 chromatin insulator sequence binding;GO:0043565 sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006355 regulation of DNA-templated transcription;GO:0033696 heterochromatin boundary formation", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VHG6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VHH7-1", "uniprot_id": "ADAL_DROME", "mass": 37576.0, "length": 337, "protein_name": "Adenosine deaminase-like protein", "gene_name": "Ada", "organism": "Fruit fly", "refseq_name": "adenosine deaminase", "refseq_ac": "NP_649866", "gene_names_uniprotkb": "Ada; CG11994", "gene_names_refseq": "ADA; Ada; CG11994; DmADA; Dmel\\CG11994; DrosADA; ada; dADA", "protein_names_uniprotkb": "Adenosine deaminase-like protein; 3.5.4.-", "protein_names_refseq": "Ada-PA; CG11994-PA; adenosine deaminase", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG11994); (R-DME-2161541); (R-DME-74217)", "pathway_count": 3, "publication_count": 2, "publication_id_list": "10731132;12537572", "class_list": "", "function": "Catalyzes the hydrolysis of the free cytosolic methylated adenosine nucleotide N(6)-methyl-AMP (N6-mAMP) to produce inositol monophosphate (IMP) and methylamine. Is required for the catabolism of cytosolic N6-mAMP, which is derived from the degradation of mRNA containing N6-methylated adenine (m6A)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A8E767", "ec_number_list": "3.5.4.-", "go_molecular_function": "GO:0004000 adenosine deaminase activity;GO:0046872 metal ion binding;GO:0062154 N6-methyl-AMP deaminase activity", "go_cellular_component": "", "go_biological_process": "GO:0006154 adenosine catabolic process;GO:0009117 nucleotide metabolic process;GO:0046103 inosine biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q9VHH7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VHN1-1", "uniprot_id": "Q9VHN1_DROME", "mass": 10957.0, "length": 96, "protein_name": "Cyclin-dependent kinases regulatory subunit", "gene_name": "Cks85A", "organism": "Fruit fly", "refseq_name": "Cyclin-dependent kinase subunit 85A, isoform B", "refseq_ac": "NP_001246992", "gene_names_uniprotkb": "Cks85A; BcDNA:GM01344; CG9790; Cks; Dmel\\CG9790; Dmel_CG9790; cks85A", "gene_names_refseq": "BcDNA:GM01344; CG9790; Cks85A; Cks; Dmel\\CG9790; cks85A", "protein_names_uniprotkb": "Cyclin-dependent kinases regulatory subunit", "protein_names_refseq": "CG9790-PB; Cks85A-PB; Cyclin-dependent kinase subunit 85A, isoform B", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG9790)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0019901 protein kinase binding;GO:0042393 histone binding;GO:0016301 kinase activity;GO:0043130 ubiquitin binding;GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity", "go_cellular_component": "GO:0019005 SCF ubiquitin ligase complex;GO:0000307 cyclin-dependent protein kinase holoenzyme complex", "go_biological_process": "GO:0000278 mitotic cell cycle;GO:0051301 cell division;GO:0007346 regulation of mitotic cell cycle;GO:0007113 endomitotic cell cycle", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VHN1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VHR6-1", "uniprot_id": "ATG13_DROME", "mass": 56927.0, "length": 523, "protein_name": "Autophagy-related protein 13 homolog", "gene_name": "Atg13", "organism": "Fruit fly", "refseq_name": "Autophagy-related 13", "refseq_ac": "NP_649796", "gene_names_uniprotkb": "Atg13; CG7331", "gene_names_refseq": "ATG13; Atg13; BcDNA:HL01508; CG7331; Dmel\\CG7331; atg13; dAtg13", "protein_names_uniprotkb": "Autophagy-related protein 13 homolog", "protein_names_refseq": "Atg13-PA; Autophagy-related 13; Autophagy-specific gene 13; CG7331-PA", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG7331); (R-DME-1632852)", "pathway_count": 2, "publication_count": 6, "publication_id_list": "10731132;12537569;12537572;18327897;19225150;20713604", "class_list": "", "function": "Autophagy factor required for autophagosome formation. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of Atg13 and Atg1. The Atg1-Atg13 complex functions at multiple levels to mediate and adjust nutrient-dependent autophagic signaling. Involved in the autophagic degradation of dBruce which controls DNA fragmentation in nurse cells., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0019887 protein kinase regulator activity", "go_cellular_component": "GO:0005829 cytosol;GO:0005776 autophagosome;GO:0000407 phagophore assembly site;GO:1990316 Atg1/ULK1 kinase complex", "go_biological_process": "GO:0000045 autophagosome assembly;GO:0042594 response to starvation;GO:0016236 macroautophagy;GO:0034497 protein localization to phagophore assembly site;GO:0000423 mitophagy", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q9VHR6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VHS7-1", "uniprot_id": "COQ2_DROME", "mass": 42935.0, "length": 392, "protein_name": "4-hydroxybenzoate polyprenyltransferase, mitochondrial", "gene_name": "Coq2", "organism": "Fruit fly", "refseq_name": "coenzyme Q biosynthesis protein 2", "refseq_ac": "NP_649789", "gene_names_uniprotkb": "Coq2; CG9613", "gene_names_refseq": "CG9613; COQ2; Coq2; Dmel\\CG9613; coq2; sbo", "protein_names_uniprotkb": "4-hydroxybenzoate polyprenyltransferase, mitochondrial; 2.5.1.39; 4-HB polyprenyltransferase; Coenzyme Q biosynthesis protein 2; PHB:PPT; PHB:polyprenyltransferase; Para-hydroxybenzoate--polyprenyltransferase", "protein_names_refseq": "CG9613-PA; Coq2-PA; coenzyme Q biosynthesis protein 2; small boy", "tax_id": 7227, "disease": "coenzyme Q10 deficiency disease (Disease Ontology:DOID:0050730); primary coenzyme Q10 deficiency 1 (Disease Ontology:DOID:0070238); glucose intolerance (Disease Ontology:DOID:10603); nephrotic syndrome (Disease Ontology:DOID:1184); multiple system atrophy (Disease Ontology:DOID:4752)", "pathway": " (dme:Dmel_CG9613); (R-DME-1268020); (R-DME-2142789)", "pathway_count": 3, "publication_count": 4, "publication_id_list": "10731132;12537569;12537572;16849596", "class_list": "", "function": "Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "7.1.2.2;3.4.24.-;2.5.1.39", "go_molecular_function": "GO:0008412 4-hydroxybenzoate polyprenyltransferase activity", "go_cellular_component": "GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0050829 defense response to Gram-negative bacterium;GO:0050830 defense response to Gram-positive bacterium;GO:0006744 ubiquinone biosynthetic process;GO:0050832 defense response to fungus;GO:0008299 isoprenoid biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q9VHS7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VHT4-1", "uniprot_id": "FUCT1_DROME", "mass": 38107.0, "length": 337, "protein_name": "GDP-fucose transporter, Golgi", "gene_name": "Gfr", "organism": "Fruit fly", "refseq_name": "neuronally altered carbohydrate", "refseq_ac": "NP_649782", "gene_names_uniprotkb": "Gfr; CG9620; nac", "gene_names_refseq": "CG9620; Dmel\\CG9620; Gfr; Nac; gfr; nac", "protein_names_uniprotkb": "GDP-fucose transporter, Golgi; Neuronally altered carbohydrate; Solute carrier family 35 member C1 homolog", "protein_names_refseq": "CG9620-PA; Gfr; golgi GDP-fucose transporter; nac-PA; neurally altered carbohydrate; neuronally altered carbohydrate; neuronally-altered-carbohydrate", "tax_id": 7227, "disease": "congenital disorder of glycosylation type II (Disease Ontology:DOID:0050571); congenital disorder of glycosylation type IIc (Disease Ontology:DOID:0070255)", "pathway": " (dme:Dmel_CG9620); (R-DME-6787639); (R-DME-727802)", "pathway_count": 3, "publication_count": 5, "publication_id_list": "10731132;12537572;15530860;19948734;22745127", "class_list": "", "function": "Involved in GDP-fucose import from the cytoplasm into the Golgi lumen (PubMed:15530860, PubMed:22745127). Plays a major role in the fucosylation of N-glycans (PubMed:15530860, PubMed:22745127). Functions redundantly with Efr in the O-fucosylation of Notch, positively regulating Notch signaling (PubMed:19948734)., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q53YF6", "ec_number_list": "", "go_molecular_function": "GO:0015297 antiporter activity;GO:0005457 GDP-fucose transmembrane transporter activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005794 Golgi apparatus;GO:0005798 Golgi-associated vesicle", "go_biological_process": "GO:0015783 GDP-fucose transmembrane transport;GO:0036085 GDP-fucose import into Golgi lumen", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q9VHT4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VHU1-1", "uniprot_id": "DDX55_DROME", "mass": 69084.0, "length": 613, "protein_name": "Probable ATP-dependent RNA helicase DDX55 homolog", "gene_name": "CG9630", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": "NP_649777", "gene_names_uniprotkb": "CG9630", "gene_names_refseq": "CG9630; DDX55; DmRH16; Dmel\\CG9630; cg9630", "protein_names_uniprotkb": "Probable ATP-dependent RNA helicase DDX55 homolog; 3.6.4.13; DEAD box protein 55", "protein_names_refseq": "CG9630-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG9630)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "10731132;12537569;12537572", "class_list": "", "function": "Probable ATP-binding RNA helicase., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.6.4.13;7.2.2.-;3.6.4.-;3.6.4.10;3.6.4.6;3.6.4.12;5.6.2.4;5.6.2.5;2.7.4.3;5.6.2.3;3.1.-.-;3.6.1.15;3.-.-.-;5.6.1.1;2.7.11.1;3.6.-.-;5.6.2.-", "go_molecular_function": "GO:0003723 RNA binding;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0003724 RNA helicase activity", "go_cellular_component": "GO:0005730 nucleolus", "go_biological_process": "GO:0010468 regulation of gene expression", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9VHU1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VIK2-1", "uniprot_id": "CART_DROME", "mass": 76193.0, "length": 674, "protein_name": "Carcinine transporter", "gene_name": "CarT", "organism": "Fruit fly", "refseq_name": "carcinine transporter, isoform A", "refseq_ac": "NP_610052", "gene_names_uniprotkb": "CarT; CG9317", "gene_names_refseq": "38E.10; CG9317; CarT; Cart; Dmel\\CG9317; carT; cart", "protein_names_uniprotkb": "Carcinine transporter", "protein_names_refseq": "CG9317-PA; CarT-PA; carcinine transporter, isoform A; carcinine transporter", "tax_id": 7227, "disease": "kidney failure (Disease Ontology:DOID:1074); extrahepatic cholestasis (Disease Ontology:DOID:13619); intrahepatic cholestasis (Disease Ontology:DOID:1852); hyperuricemia (Disease Ontology:DOID:1920); asthma (Disease Ontology:DOID:2841); acute kidney failure (Disease Ontology:DOID:3021); end stage renal disease (Disease Ontology:DOID:783)", "pathway": " (dme:Dmel_CG9317); (R-DME-112311); (R-DME-181430); (R-DME-196807); (R-DME-200425); (R-DME-2161517); (R-DME-442660); (R-DME-549127); (R-DME-561048); (R-DME-917937); (R-DME-9749641); (R-DME-9793528)", "pathway_count": 12, "publication_count": 5, "publication_id_list": "10731132;12537569;12537572;26653853;26713872", "class_list": "", "function": "Carcinine transporter which is required for recycling of the neurotransmitter histamine in photoreceptor neurons of the compound eye. Following histamine release from photoreceptors and its uptake by glia where it is converted to carcinine, required for the uptake of carcinine from glia into photoreceptor cells where it can be hydrolyzed by tan to form histamine and beta-alanine., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 4, "predicted_n_glycosites": 3, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 7, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "Q961U9", "ec_number_list": "", "go_molecular_function": "GO:0005326 neurotransmitter transmembrane transporter activity;GO:1905131 carcinine transmembrane transporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0043679 axon terminus", "go_biological_process": "GO:0007601 visual perception;GO:0001504 neurotransmitter uptake;GO:0050908 detection of light stimulus involved in visual perception;GO:0046956 positive phototaxis;GO:1905130 carcinine import across plasma membrane", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q9VIK2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VIL0-1", "uniprot_id": "BRUN_DROME", "mass": 145958.0, "length": 1320, "protein_name": "Protein brunelleschi", "gene_name": "brun", "organism": "Fruit fly", "refseq_name": "brunelleschi", "refseq_ac": "NP_610044", "gene_names_uniprotkb": "brun; CG2478; bru", "gene_names_refseq": "38D.28; CG2478; Dmel\\CG2478; TRAPPC9; brun; bru; dTRAPPC9", "protein_names_uniprotkb": "Protein brunelleschi; NIK- and IKBKB-binding protein", "protein_names_refseq": "CG2478-PA; brun-PA; brunelleschi", "tax_id": 7227, "disease": "autosomal recessive intellectual developmental disorder 13 (Disease Ontology:DOID:0081098); intellectual disability (Disease Ontology:DOID:1059); attention deficit hyperactivity disorder (Disease Ontology:DOID:1094)", "pathway": " (dme:Dmel_CG2478); (R-DME-204005); (R-DME-8876198)", "pathway_count": 3, "publication_count": 6, "publication_id_list": "10731132;12537569;12537572;17372656;18327897;19934220", "class_list": "", "function": "Cooperates with Rab11 and fwd/PI4K to mediate the flow of membrane through the Golgi, which is required to support cleavage furrow ingression, therefore promoting cytokinesis in male meiotic cells., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q3KN61;Q961K0", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005794 Golgi apparatus;GO:0005802 trans-Golgi network;GO:0030008 TRAPP complex;GO:1990071 TRAPPII protein complex", "go_biological_process": "GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0048193 Golgi vesicle transport;GO:0000916 actomyosin contractile ring contraction;GO:0000212 meiotic spindle organization;GO:0006891 intra-Golgi vesicle-mediated transport", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q9VIL0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VIT3-1", "uniprot_id": "Q9VIT3_DROME", "mass": 42464.0, "length": 381, "protein_name": "Msb1l", "gene_name": "msb1l", "organism": "Fruit fly", "refseq_name": "msb1l", "refseq_ac": "NP_609991", "gene_names_uniprotkb": "msb1l; CG10364; Dmel\\CG10364; Dmel_CG10364; Msb1l; msh1l", "gene_names_refseq": "CG10364; Dmel\\CG10364; Msb1l; msb1l; msh1l", "protein_names_uniprotkb": "Msb1l", "protein_names_refseq": "CG10364-PA; msb1l-PA; msb1l", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG10364)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q960W4", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VIT3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VIV3-1", "uniprot_id": "CTU2_DROME", "mass": 44773.0, "length": 405, "protein_name": "Cytoplasmic tRNA 2-thiolation protein 2", "gene_name": "Ctu2", "organism": "Fruit fly", "refseq_name": "cytosolic thiouridylase subunit 2, isoform B", "refseq_ac": "NP_001260585", "gene_names_uniprotkb": "Ctu2; CG10189", "gene_names_refseq": "CG10189; CTU2; Ctu2; Dmel\\CG10189; i180; i199", "protein_names_uniprotkb": "Cytoplasmic tRNA 2-thiolation protein 2; Cytosolic thiouridylase subunit 2", "protein_names_refseq": "CG10189-PB; Ctu2-PB; cytosolic thiouridylase subunit 2, isoform B", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG10189)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "10731132;12537569;12537572", "class_list": "", "function": "Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with NCS6/CTU1 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "B5X547;M9PDQ5;Q8MT91", "ec_number_list": "", "go_molecular_function": "GO:0016783 sulfurtransferase activity;GO:0000049 tRNA binding;GO:0016779 nucleotidyltransferase activity", "go_cellular_component": "GO:0005829 cytosol;GO:0002144 cytosolic tRNA wobble base thiouridylase complex", "go_biological_process": "GO:0002143 tRNA wobble position uridine thiolation;GO:0034227 tRNA thio-modification;GO:0002098 tRNA wobble uridine modification;GO:0032447 protein urmylation", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9VIV3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VJ34-1", "uniprot_id": "GSTCD_DROME", "mass": 66005.0, "length": 585, "protein_name": "Glutathione S-transferase C-terminal domain-containing protein homolog", "gene_name": "CG10428", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": "NP_609918", "gene_names_uniprotkb": "CG10428", "gene_names_refseq": "CG10428; Dmel\\CG10428", "protein_names_uniprotkb": "Glutathione S-transferase C-terminal domain-containing protein homolog", "protein_names_refseq": "CG10428-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG10428)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "10731132;12537569;12537572", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q95TQ9", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9VJ34-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VJ71-1", "uniprot_id": "CP310_DROME", "mass": 57113.0, "length": 492, "protein_name": "Probable cytochrome P450 310a1", "gene_name": "Cyp310a1", "organism": "Fruit fly", "refseq_name": "cytochrome P450 310a1", "refseq_ac": "NP_609891", "gene_names_uniprotkb": "Cyp310a1; CG10391", "gene_names_refseq": "310a1; CG10391; Cyp310a1; Cyp310a; Cyp310; Dmel\\CG10391; H; anon-EST:CL1d7; cyp310a1", "protein_names_uniprotkb": "Probable cytochrome P450 310a1; 1.14.-.-; CYPCCCXA1", "protein_names_refseq": "CG10391-PA; Cyp310a1-PA; cytochrome P450 310a1; cytochrome P450", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG10391)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "10731132;12537569;12537572", "class_list": "", "function": "May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0004497 monooxygenase activity;GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9VJ71-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VJ83-1", "uniprot_id": "GRND_DROME", "mass": 26267.0, "length": 241, "protein_name": "Tumor necrosis factor receptor superfamily member grnd", "gene_name": "grnd", "organism": "Fruit fly", "refseq_name": "grindelwald, isoform C", "refseq_ac": "NP_001260538", "gene_names_uniprotkb": "grnd; CG10176", "gene_names_refseq": "CG10176; Dmel\\CG10176; Grnd; grnd", "protein_names_uniprotkb": "Tumor necrosis factor receptor superfamily member grnd; Protein grindelwald", "protein_names_refseq": "CG10176-PC; grindelwald, isoform C; grindelwald; grnd-PC", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG10176)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "10731132;12537572;25874673;27076079;29870719;33824334;38944657", "class_list": "", "function": "Acts as a receptor for TNF-cytokine egr (PubMed:25874673, PubMed:27076079, PubMed:33824334). Plays a role in activation of JNK signaling and is required for egr-induced apoptosis, including in wing imaginal discs during development (PubMed:25874673, PubMed:33824334). May also play an egr-independent role in cell proliferation (PubMed:25874673). TNF receptor involved in triggering JNK-dependent proliferation of the enteroblast-enterocyte lineage in response to stress-induced release of egr by intestinal stem cells and enteroblasts (PubMed:38944657). Involved in regulation of insulin production in response to dietary protein shortage keeping systemic growth in check (PubMed:27076079). Activation in brain insulin producing cells through binding of egr released into the hemolymph in response to dietary amino acid shortage, results in JNK-dependent inhibition of insulin production (PubMed:27076079)., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 7, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q8SXT4", "ec_number_list": "", "go_molecular_function": "GO:0005031 tumor necrosis factor receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016324 apical plasma membrane;GO:0030659 cytoplasmic vesicle membrane", "go_biological_process": "GO:1903427 negative regulation of reactive oxygen species biosynthetic process;GO:0046330 positive regulation of JNK cascade;GO:0033209 tumor necrosis factor-mediated signaling pathway;GO:0043068 positive regulation of programmed cell death;GO:1904801 positive regulation of neuron remodeling", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q9VJ83-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VJ87-1", "uniprot_id": "CWC22_DROME", "mass": 151637.0, "length": 1330, "protein_name": "Pre-mRNA-splicing factor CWC22 homolog", "gene_name": "ncm", "organism": "Fruit fly", "refseq_name": "nucampholin", "refseq_ac": "NP_609877", "gene_names_uniprotkb": "ncm; CG12750", "gene_names_refseq": "CG12750; Dmel\\CG12750; E-2a; NCM; Ncm; l(2)SH0931; l(2)SH2 0931; ncm", "protein_names_uniprotkb": "Pre-mRNA-splicing factor CWC22 homolog; Nucampholin", "protein_names_refseq": "CG12750-PA; lethal (2) SH0931; ncm-PA; nucampholin", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG12750); (R-DME-72163)", "pathway_count": 2, "publication_count": 7, "publication_id_list": "10731132;12537569;12537572;15998720;17372656;18327897;22961380", "class_list": "", "function": "Required for pre-mRNA splicing and for exon-junction complex (EJC) assembly. Hinders eIF4AIII from non-specifically binding RNA and escorts it to the splicing machinery to promote EJC assembly on mature mRNAs., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 10, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A8WHI6;C9QPF2;Q8SXP2;Q95R63", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding", "go_cellular_component": "GO:0016607 nuclear speck;GO:0005681 spliceosomal complex;GO:0071013 catalytic step 2 spliceosome", "go_biological_process": "GO:0000398 mRNA splicing, via spliceosome", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q9VJ87-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VJB6-1", "uniprot_id": "CADN2_DROME", "mass": 200480.0, "length": 1799, "protein_name": "Putative neural-cadherin 2", "gene_name": "CadN2", "organism": "Fruit fly", "refseq_name": "Cadherin-N2, isoform C", "refseq_ac": "NP_001036368", "gene_names_uniprotkb": "CadN2; CG42829; CG7527", "gene_names_refseq": "CG42829; CG7527; CT23007; CadN2; DN-Cad2; DN-cad2; DN-like; DNcad2; DmNCad2; Dmel\\CG42829; N-Cad2; NCad2; Ncad2; cadN2", "protein_names_uniprotkb": "Putative neural-cadherin 2; Cadherin-N2; dN2-cadherin", "protein_names_refseq": "CG42829-PC; CadN2-PC; Cadherin-N2, isoform C; DN-cadh-like; DN-cadherin; N-cadherin2; cadherin N2r", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG42829)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "10731132;12537572", "class_list": "", "function": "Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells (By similarity)., [UniProtKB]", "predicted_glycosites": 16, "predicted_n_glycosites": 16, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 16, "binding_glycan_count": 0, "secondary_ac_list": "G4LU36;Q0E8P8", "ec_number_list": "", "go_molecular_function": "GO:0005509 calcium ion binding;GO:0045296 cadherin binding;GO:0008013 beta-catenin binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016342 catenin complex", "go_biological_process": "GO:0016477 cell migration;GO:0031175 neuron projection development;GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules;GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0044331 cell-cell adhesion mediated by cadherin", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q9VJB6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VJC7-1", "uniprot_id": "EFTS_DROME", "mass": 35412.0, "length": 318, "protein_name": "Elongation factor Ts, mitochondrial", "gene_name": "mEFTs", "organism": "Fruit fly", "refseq_name": "mitochondrial translation elongation factor Ts", "refseq_ac": "NP_609847", "gene_names_uniprotkb": "mEFTs; CG6412", "gene_names_refseq": "CG6412; Dmel\\CG6412; mEFTs; mtEF-Ts", "protein_names_uniprotkb": "Elongation factor Ts, mitochondrial; EF-TsMt; EF-Ts", "protein_names_refseq": "CG6412-PA; mEFTs-PA; mitochondrial translation elongation factor Ts", "tax_id": 7227, "disease": "combined oxidative phosphorylation deficiency 3 (Disease Ontology:DOID:0111486)", "pathway": " (dme:Dmel_CG6412)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "10731132;12537569;12537572", "class_list": "", "function": "Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005085 guanyl-nucleotide exchange factor activity;GO:0003746 translation elongation factor activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0070125 mitochondrial translational elongation", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9VJC7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VJK8-1", "uniprot_id": "JHAMT_DROME", "mass": 34065.0, "length": 297, "protein_name": "Juvenile hormone acid O-methyltransferase", "gene_name": "jhamt", "organism": "Fruit fly", "refseq_name": "juvenile hormone acid methyltransferase, isoform B", "refseq_ac": "NP_001285980", "gene_names_uniprotkb": "jhamt; CG17330", "gene_names_refseq": "BG:DS09218.5; CG17330; DmJHAMT; Dmel\\CG17330; JAHMT; JHAMT; JHamt; Jhamt; jhamt", "protein_names_uniprotkb": "Juvenile hormone acid O-methyltransferase; 2.1.1.325; DmJHAMT; Juvenile hormone acid methyltransferase", "protein_names_refseq": "CG17330-PB; jhamt-PB; juvenile hormone acid O-Methyl transferase; juvenile hormone acid O-Methyltransferase; juvenile hormone acid methyl transferase; juvenile hormone acid methyltransferase, isoform B", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG17330)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "10731132;12537569;12537572;18549957", "class_list": "", "function": "O-methyltransferase that transfers a methyl group from S-adenosyl-L-methionine (SAM) to the carboxyl group of juvenile hormone acids to produce active juvenile hormones in the corpora allata, the last step during juvenile hormone biosynthesis (PubMed:18549957). Also able to methylate farnesoate to methyl farnesoate (PubMed:18549957)., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q767F0;Q8T900", "ec_number_list": "2.1.1.325", "go_molecular_function": "GO:0008168 methyltransferase activity;GO:0019010 farnesoic acid O-methyltransferase activity", "go_cellular_component": "", "go_biological_process": "GO:0008049 male courtship behavior;GO:0032259 methylation;GO:0006718 juvenile hormone biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q9VJK8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VJV8-1", "uniprot_id": "DPOG2_DROME", "mass": 41027.0, "length": 361, "protein_name": "DNA polymerase subunit gamma-2, mitochondrial", "gene_name": "PolG2", "organism": "Fruit fly", "refseq_name": "DNA polymerase gamma subunit 2", "refseq_ac": "NP_001027262", "gene_names_uniprotkb": "PolG2; CG33650; DNApol-gamma35; DNApol-gamma; DNApolG2; MtPolB; l(2)34De; l(2)br16; pol gamma-beta", "gene_names_refseq": "BG:DS00941.9; CG33084; CG33650; CG8969; D-pol gamma-beta; DNA pol-gam.35; DNApol-gamma.35; DNApol-gamma35; DNApol-gamma; DNApolg-35; Dmel\\CG33650; MtPolB; POLG; Pol gamma; PolG2; PolG; Polgamma-35; Polgamma-beta; Polgamma; Polg; br16; l(2)34De; l(2)br16; pol gamma-alpha; pol gamma-beta; pol gamma35; polgamma-beta; polgamma", "protein_names_uniprotkb": "DNA polymerase subunit gamma-2, mitochondrial; DNA polymerase beta subunit; DNA polymerase gamma 35kD subunit; DNA polymerase gamma subunit 2", "protein_names_refseq": "CG33650-PA; DNA polymerase -gamma; DNA polymerase gamma 35kD subunit; DNA polymerase gamma subunit 2; DNA polymerase gamma subunit alpha; DNA polymerase gamma; PolG2-PA; accessory subunit of mitochondrial DNA polymerase; accessory(beta)subunit; beta subunit; lethal 16 in the black-reduced region; lethal(2)34De; mitochondrial DNA polymerase accessory subunit; mitochondrial gamma polymerase", "tax_id": 7227, "disease": "mitochondrial DNA depletion syndrome 16 (Disease Ontology:DOID:0070446); mitochondrial DNA depletion syndrome 16B (Disease Ontology:DOID:0070447); autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions 4 (Disease Ontology:DOID:0111525); nephrocalcinosis (Disease Ontology:DOID:12679)", "pathway": " (dme:Dmel_CG33650); (R-DME-9913635)", "pathway_count": 2, "publication_count": 9, "publication_id_list": "10731132;10930405;11917141;12537569;12537572;19924234;3095323;7499423;9153213", "class_list": "", "function": "As accessory component of the DNA polymerase gamma complex is involved in the replication of mitochondrial DNA (PubMed:3095323, PubMed:7499423). Does not bind DNA (PubMed:7499423). Essential for mitochondrial DNA maintenance and larval development (PubMed:11917141, PubMed:19924234)., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "O02005;Q9NKE7", "ec_number_list": "", "go_molecular_function": "GO:0030337 DNA polymerase processivity factor activity;GO:0003727 single-stranded RNA binding;GO:0071667 DNA/RNA hybrid binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix;GO:0005760 gamma DNA polymerase complex", "go_biological_process": "GO:0006264 mitochondrial DNA replication;GO:0006261 DNA-templated DNA replication", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "Q9VJV8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VJY9-1", "uniprot_id": "LOQS_DROME", "mass": 50085.0, "length": 465, "protein_name": "Protein Loquacious", "gene_name": "loqs", "organism": "Fruit fly", "refseq_name": "loquacious, isoform D", "refseq_ac": "NP_001188796", "gene_names_uniprotkb": "loqs; CG6866; Dmel\\CG6866; Dmel_CG6866; LOQS; Loqs-PD; Loqs; LqPD; R3D1-L; R3D1-S; R3D1; TRBP; cg6866; dRax; loq; r3d1", "gene_names_refseq": "CG6866; Dmel\\CG6866; LOQS; Loqs-PD; Loqs; LqPD; R3D1-L; R3D1-S; R3D1; TRBP; cg6866; dRax; loqs; loq; r3d1", "protein_names_uniprotkb": "Protein Loquacious", "protein_names_refseq": "CG6866-PD; loqs-PD; loquacious, isoform D; loquacious", "tax_id": 7227, "disease": "dystonia 16 (Disease Ontology:DOID:0090048)", "pathway": " (dme:Dmel_CG6866); (R-DME-203927); (R-DME-426486); (R-DME-9833482)", "pathway_count": 4, "publication_count": 34, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;15918769;15918770;15985611;16110336;17320391;17569856;17569867;17666393;17928574;19451544;19635780;19644447;21245036;23063653;25589440;25891075;26109356;26109357;26769856;27184838;28874570;29040648;29373753;29550490;34590626;35768513;36057690;36182693", "class_list": "", "function": "Double-stranded RNA-binding protein which can function in gene silencing by acting with Dcr-1 to enhance its ATP-independent processing of a specific subset of precursor micro-RNAs (pre-miRNAs) to mature miRNAs (PubMed:19635780, PubMed:26769856, PubMed:27184838). Some reports found it was able to enhance the efficiency of pre-miRNA processing by Dcr-1, and can shift the cleavage site of Dcr-1 altering the length of the mature miRNAs produced by Dcr-1 alone (PubMed:17320391, PubMed:23063653, PubMed:29373753). However, in contrast to isoform PB, it is not necessary or sufficient for enhancing miRNA biogenesis, and is not required for development or female germline stem cell (GSC) maintenance (PubMed:17320391, PubMed:23063653). Another report also found that it decreases binding of Dcr-1 to the miRNA substrate let-7 (PubMed:17928574)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]; Double-stranded RNA-binding protein which functions in gene silencing by acting with Dcr-1 to enhance its ATP-independent processing of a specific subset of precursor micro-RNAs (pre-miRNAs) to mature miRNAs (PubMed:15918769, PubMed:15985611, PubMed:17666393, PubMed:17928574, PubMed:19635780, PubMed:26769856, PubMed:27184838, PubMed:36182693). Function is essential for development and female germline stem cell (GSC) maintenance (PubMed:15985611, PubMed:17320391, PubMed:23063653). Functions in miRNA-mediated gene silencing by enhancing the binding affinity and specific pre-miRNA processing activity of Dcr-1, and as part of the loqs-PB-Dcr-1 complex, is involved in substrate discrimination, correctly positioning the pre-miRNA in the Dcr-1 catalytic center for cleavage, and miRNA loading into the Argonaute 1 (Ago1)-containing RNA-induced silencing complex (miRISC) (PubMed:15918769, PubMed:17666393, PubMed:17928574, PubMed:23063653, PubMed:27184838, PubMed:36182693). Increases the binding affinity of Dcr-1 to pre-miRNAs, thereby increasing dicing efficiency and broadening the range of substrates that can be processed by the dicer (PubMed:17928574, PubMed:23063653, PubMed:27184838, PubMed:36182693). It may also confer the substrate specificity of Dcr-1 towards pre-miRNAs, as in its absence Dcr-1 displays siRNA-generating activity towards long dsRNA substrates (PubMed:15918769). It can also shift the cleavage site of Dcr-1 for a small number of pre-miRNAs, changing the length of the mature miRNAs produced by Dcr-1 alone (PubMed:23063653, PubMed:29373753). Increases the range of pre-miRNAs that can be processed by Dcr-1, by enhancing the dicing of suboptimal hairpin substrates including ones with mismatches at the dicing site (PubMed:27184838, PubMed:29373753). This function may also promote the generation of novel miRNA genes as it appears to have an important role in processing evolutionarily young miRNA genes, suggesting that it may also enhance dicing of substrates that have not acquired hairpin features required for efficient miRNA processing (PubMed:27184838). As newly emerged miRNAs can have deleterious or beneficial effects on fitness, this function is likely part of a regulatory system that prevents excessive emergence of active miRNA genes and thus keeps them within an optimal range (PubMed:27184838). Also forms a RISC loading complex (miRLC) with Dcr-1 to mediate Ago1-loading of mature miRNAs into the RNA-induced silencing complex (miRISC) (PubMed:15918769, PubMed:36182693). In female ovaries, required for Dcr-1 to generate the twenty-three nucleotide isomiR variant of miR-307a which is able to repress its targets Gk2 and tara (PubMed:23063653)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]; Double-stranded RNA-binding protein which has an essential role in gene silencing (RNAi) by acting with Dcr-2 to enhance its ATP-dependent processing of a subset of endogenous (endo) and exogenous (exo) dsRNAs into short interfering RNAs (siRNAs) (PubMed:19635780, PubMed:19644447, PubMed:21245036, PubMed:23063653, PubMed:25891075, PubMed:27184838, PubMed:28874570, PubMed:29040648, PubMed:29550490, PubMed:34590626). Functions in RNAi by increasing the initial binding affinity of Dcr-2 to certain dsRNA substrates, and in the absence of r2d2, may also function in siRNA loading into the Argonaute 2 (AGO2)-containing RNA-induced silencing complex (siRISC) and guide strand selection for target silencing by the siRISC (PubMed:19635780, PubMed:19644447, PubMed:21245036, PubMed:29550490). Promotes Dcr-2 cleavage of a subset of dsRNAs, including endo-dsRNAs derived from convergent transcription, inverted repeats and transposons (PubMed:19635780, PubMed:19644447, PubMed:21245036, PubMed:23063653, PubMed:29550490). Also enables Dcr-2 to produce hairpin-derived endo-siRNAs in the presence of cellular inhibitory inorganic phosphate, likely by increasing the binding affinity of the enzyme to the hairpin dsRNAs allowing the dsRNA to displace phosphate bound to Dcr-2 (PubMed:29550490). According to many reports, the cleavage reaction mode of Dcr-2 changes according to the termini of the dsRNA substrate, with the enzyme displaying a preference for processing blunt termini (BLT), likely non-self dsRNAs, over dsRNAs with 2 nucleotides 3' overhanging (3'ovr) termini, which are typically the structure of endo-dsRNAs (PubMed:25891075, PubMed:29550490, PubMed:34590626). According to many reports, interaction with Loqs-PD modifies the molecular recognition mechanisms of Dcr-2 towards sub-optimal 3'ovr dsRNA substrates and thus enables the dicer to cleave endo-dsRNA templates with diverse termini (PubMed:25891075, PubMed:29550490). However, according to another report, the mode of cleavage reaction is not affected by the presence or absence of loqs-PD (PubMed:34590626). In the absence of r2d2, may also form an alternative RISC loading complex (siRLC) with Dcr-2 to mediate AGO2-loading of endo- and exo-siRNAs into the RNA-induced silencing complex (siRISC) (PubMed:21245036, PubMed:29040648). Many reports suggest that loqs-PD and r2d2 function independently with dcr-2 in distinct siRNA pathways, and may even compete for binding to the enzyme (PubMed:21245036, PubMed:29040648). Loaded siRNAs serve as a guide to direct the siRISC to complementary RNAs to degrade them or prevent their translation (PubMed:29040648). The siRLC plays an important role in the ATP-dependent asymmetry sensing of the duplex, and is therefore also responsible for the selection of the strand that ultimately acts as the guide siRNA for the siRISC (PubMed:29040648). Thermodynamically asymmetric endo-siRNAs can be pre-oriented in the siRLC by the Loqs-PD and DCr-2 complex, which preferentially binds to the most thermodynamically stable strand prior to loading into the siRISC (PubMed:29040648). Appears to be involved in promoting double-strand breaks (DSBs) following exposure to a low-dose/dose-rate (LDR) of ionizing radiation (PubMed:36057690)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 8, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "M9MRT5;Q4TZM6;Q8IP72;Q8SZ74", "ec_number_list": "", "go_molecular_function": "GO:1905172 RISC complex binding;GO:0003725 double-stranded RNA binding;GO:0035197 siRNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0016442 RISC complex;GO:0070578 RISC-loading complex", "go_biological_process": "GO:0070922 RISC complex assembly;GO:0007417 central nervous system development;GO:0010586 miRNA metabolic process;GO:0031054 pre-miRNA processing;GO:0030422 siRNA processing", "synthesized_glycan_count": 0, "hit_score": 3.5, "record_id": "Q9VJY9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VJZ6-1", "uniprot_id": "Q9VJZ6_DROME", "mass": 23631.0, "length": 216, "protein_name": "Glutaredoxin 3", "gene_name": "Grx3", "organism": "Fruit fly", "refseq_name": "glutaredoxin 3", "refseq_ac": "NP_609641", "gene_names_uniprotkb": "Grx3; CG6523; Dmel\\CG6523; Dmel_CG6523; Grx4", "gene_names_refseq": "CG6523; Dmel\\CG6523; Grx3; Grx4", "protein_names_uniprotkb": "Glutaredoxin 3", "protein_names_refseq": "CG6523-PA; Grx3-PA; glutaredoxin 3", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG6523)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0046872 metal ion binding;GO:0051536 iron-sulfur cluster binding;GO:0141049 protein-glutathione oxidoreductase (glutathione) activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol", "go_biological_process": "GO:0006879 intracellular iron ion homeostasis", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VJZ6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VK50-1", "uniprot_id": "ACXE_DROME", "mass": 128918.0, "length": 1123, "protein_name": "Adenylyl cyclase X E", "gene_name": "ACXE", "organism": "Fruit fly", "refseq_name": "adenylyl cyclase X E", "refseq_ac": "NP_652601", "gene_names_uniprotkb": "ACXE; CG17178", "gene_names_refseq": "ACXE; AC; CG17178; DACXE; Dmel\\CG17178", "protein_names_uniprotkb": "Adenylyl cyclase X E; 4.6.1.1", "protein_names_refseq": "ACXE-PB; CG17178-PB; adenylyl cyclase X E", "tax_id": 7227, "disease": "congenital heart disease (Disease Ontology:DOID:1682); chronic obstructive pulmonary disease (Disease Ontology:DOID:3083)", "pathway": " (dme:Dmel_CG17178); (R-DME-163615); (R-DME-170660); (R-DME-170670); (R-DME-418597); (R-DME-5610787)", "pathway_count": 6, "publication_count": 3, "publication_id_list": "10731132;12537572;19046378", "class_list": "", "function": "Catalyzes the formation of the signaling molecule cAMP in response to G protein signaling., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "F3YDG3", "ec_number_list": "4.6.1.1", "go_molecular_function": "GO:0004016 adenylate cyclase activity;GO:0005524 ATP binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane", "go_biological_process": "GO:0006171 cAMP biosynthetic process;GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0035556 intracellular signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9VK50-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VK91-1", "uniprot_id": "FAM92_DROME", "mass": 45179.0, "length": 395, "protein_name": "CBY1-interacting BAR domain-containing protein homolog", "gene_name": "Fam92", "organism": "Fruit fly", "refseq_name": "Fam92", "refseq_ac": "NP_609564", "gene_names_uniprotkb": "Fam92; CG6405", "gene_names_refseq": "CG6405; Dmel\\CG6405; FAM92; Fam92; fam92", "protein_names_uniprotkb": "CBY1-interacting BAR domain-containing protein homolog; Protein Fam92", "protein_names_refseq": "CG6405-PA; Fam92-PA; Fam92", "tax_id": 7227, "disease": "polydactyly (Disease Ontology:DOID:1148)", "pathway": " (dme:Dmel_CG6405)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "10731132;12537572;31821146;33370260", "class_list": "", "function": "Component of the DZIP1-Fam92-Cby complex which promotes ciliogenesis in sensory neurons and spermatocytes by acting downstream of Cep290 to initiate early ciliary membrane formation and thus transition zone (TZ) assembly (PubMed:31821146). During spermatogenesis, also regulates distal elongation of the basal-body and their docking (anchoring) to the plasma membrane and as a consequence, regulates the initiation and proper elongation of axonemal microtubules (PubMed:31821146). Within the complex, required to recruit or stabilize Cby at the distal basal body of cilia to promote DZIP1-mediated early ciliary membrane formation and initiate TZ assembly (PubMed:31821146, PubMed:33370260). May also act with Dzip1 to restrict Cep290 localization to the proximal part of the TZ (PubMed:31821146). May also be involved in recruitment or stabilization of Mks1 at the TZ (PubMed:31821146)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q95SS2", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0030425 dendrite;GO:0036064 ciliary basal body;GO:0035869 ciliary transition zone", "go_biological_process": "GO:0050709 negative regulation of protein secretion;GO:0060271 cilium assembly", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q9VK91-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VKA5-1", "uniprot_id": "GR33A_DROME", "mass": 54585.0, "length": 475, "protein_name": "Gustatory and pheromone receptor 33a", "gene_name": "Gr33a", "organism": "Fruit fly", "refseq_name": "gustatory receptor 33a", "refseq_ac": "NP_525102", "gene_names_uniprotkb": "Gr33a; CG17213", "gene_names_refseq": "CG17213; Dmel\\CG17213; GR33a; Gr33C1; Gr33a", "protein_names_uniprotkb": "Gustatory and pheromone receptor 33a", "protein_names_refseq": "CG17213-PA; Gr33a-PA; gustatory receptor 33C1; gustatory receptor 33a", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG17213)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "10731132;11516643;12537572;19765987;20797533;22031876", "class_list": "", "function": "Gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates. Required for sensing all nonvolatile repulsive chemicals, including tastants, pheromones, and especially N,N-Diethyl-meta-toluamide (DEET), the most widely used insect repellent worldwide. Also functions as a pheromone receptor for a male inhibitory pheromone leading to male-male courtship suppression., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0015276 ligand-gated monoatomic ion channel activity;GO:0008527 taste receptor activity;GO:0170021 ionotropic taste receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane;GO:0030424 axon;GO:0030425 dendrite;GO:0043025 neuronal cell body", "go_biological_process": "GO:0008049 male courtship behavior;GO:0060179 male mating behavior;GO:0007165 signal transduction;GO:0034220 monoatomic ion transmembrane transport;GO:0009636 response to toxic substance", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q9VKA5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VKH0-1", "uniprot_id": "COG8_DROME", "mass": 64910.0, "length": 570, "protein_name": "Conserved oligomeric Golgi complex subunit 8", "gene_name": "Cog8", "organism": "Fruit fly", "refseq_name": "component of oligomeric golgi complex 8", "refseq_ac": "NP_609503", "gene_names_uniprotkb": "Cog8; CG6488", "gene_names_refseq": "CG6488; COG8; Cog8; Dmel\\CG6488", "protein_names_uniprotkb": "Conserved oligomeric Golgi complex subunit 8; COG complex subunit 8; Component of oligomeric Golgi complex 8", "protein_names_refseq": "CG6488-PA; Cog8-PA; component of oligomeric golgi complex 8", "tax_id": 7227, "disease": "congenital disorder of glycosylation type IIh (Disease Ontology:DOID:0070260)", "pathway": " (dme:Dmel_CG6488); (R-DME-6807878); (R-DME-6811438); (R-DME-6811440)", "pathway_count": 4, "publication_count": 3, "publication_id_list": "10731132;12537569;12537572", "class_list": "", "function": "Required for normal Golgi function., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A9UNB2;Q8T9C7", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0017119 Golgi transport complex", "go_biological_process": "GO:0015031 protein transport;GO:0007030 Golgi organization;GO:0000301 retrograde transport, vesicle recycling within Golgi;GO:0006891 intra-Golgi vesicle-mediated transport;GO:0007290 spermatid nucleus elongation", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9VKH0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VKV5-1", "uniprot_id": "CD2B2_DROME", "mass": 36838.0, "length": 319, "protein_name": "CD2 antigen cytoplasmic tail-binding protein 2 homolog", "gene_name": "holn1", "organism": "Fruit fly", "refseq_name": "hole-in-one", "refseq_ac": "NP_609404", "gene_names_uniprotkb": "holn1; CG5198", "gene_names_refseq": "CG5198; Dmel\\CG5198; holn1", "protein_names_uniprotkb": "CD2 antigen cytoplasmic tail-binding protein 2 homolog; Protein hole-in-one", "protein_names_refseq": "CG5198-PA; hole-in-one; holn1-PA", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG5198)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "10731132;12537569;12537572;18327897;19884309;22140578", "class_list": "", "function": "Required for embryonic epithelial tissue repair, but not for the assembly of the actomyosin cable at the wound edge. Probably acts downstream of rl in the regulation of Ddc and msn transcription to promote wound healing., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "C4XVH8;Q8T0Q7", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005682 U5 snRNP", "go_biological_process": "GO:0048749 compound eye development;GO:0090303 positive regulation of wound healing;GO:0042060 wound healing;GO:0022416 chaeta development;GO:0035220 wing disc development", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q9VKV5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VKV8-1", "uniprot_id": "CFA20_DROME", "mass": 23331.0, "length": 199, "protein_name": "Cilia- and flagella-associated protein 20", "gene_name": "Bug22", "organism": "Fruit fly", "refseq_name": "basal body up regulated gene 22", "refseq_ac": "NP_609402", "gene_names_uniprotkb": "Bug22; CFAP20; CG5343", "gene_names_refseq": "Bug22; CG5343; Dmel\\CG5343", "protein_names_uniprotkb": "Cilia- and flagella-associated protein 20; Basal body up-regulated protein 22", "protein_names_refseq": "Bug22-PA; CG5343-PA; basal body up regulated gene 22 ortholog; basal body up regulated gene 22", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG5343)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "10731132;12537569;12537572;24414207", "class_list": "", "function": "Cilium- and flagellum-specific protein that plays a role in axonemal structure organization and motility (PubMed:24414207). Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating (By similarity). Involved in the regulation of the size and morphology of cilia. Required for sperm individualization, differentiation of the sperm flagellum and tubulin polyglycylation of axonemal microtubules., [UniProtKB, PubMed, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005730 nucleolus;GO:0005929 cilium;GO:0031514 motile cilium;GO:0036126 sperm flagellum", "go_biological_process": "GO:0060271 cilium assembly;GO:2000147 positive regulation of cell motility;GO:0000398 mRNA splicing, via spliceosome;GO:0040011 locomotion;GO:0018094 protein polyglycylation", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q9VKV8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VL18-1", "uniprot_id": "EF1D_DROME", "mass": 28935.0, "length": 256, "protein_name": "Probable elongation factor 1-delta", "gene_name": "eEF1delta", "organism": "Fruit fly", "refseq_name": "eukaryotic translation elongation factor 1 delta, isoform B", "refseq_ac": "NP_609361", "gene_names_uniprotkb": "eEF1delta; CG4912", "gene_names_refseq": "CG4912; Dmel\\CG4912; eEF1delta; eEF1d; eEf1delta", "protein_names_uniprotkb": "Probable elongation factor 1-delta; EF-1-delta", "protein_names_refseq": "CG4912-PB; eEF1delta-PB; eukaryotic translation elongation factor 1 delta, isoform B; eukaryotic translation elongation factor 1delta", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG4912); (R-DME-156842)", "pathway_count": 2, "publication_count": 5, "publication_id_list": "10731132;12537569;12537572;17372656;18327897", "class_list": "", "function": "EF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9VL19", "ec_number_list": "", "go_molecular_function": "GO:0005085 guanyl-nucleotide exchange factor activity;GO:0003746 translation elongation factor activity", "go_cellular_component": "GO:0005829 cytosol;GO:0005853 eukaryotic translation elongation factor 1 complex", "go_biological_process": "GO:0006414 translational elongation", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q9VL18-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VL78-1", "uniprot_id": "FKB59_DROME", "mass": 48795.0, "length": 439, "protein_name": "FK506-binding protein 59", "gene_name": "Fkbp59", "organism": "Fruit fly", "refseq_name": "FK506-binding protein 59kD, isoform B", "refseq_ac": "NP_001285784", "gene_names_uniprotkb": "Fkbp59; CG4535; Dmel\\CG4535; Dmel_CG4535; FKBP59-bp1; FKBP59; anon-WO0118547.161; dFKBP4; dFKBP59; fkbp59; l(2)k00424; l(2)k09010", "gene_names_refseq": "CG4535; Dmel\\CG4535; FKBP59-bp1; FKBP59; Fkbp59; anon-WO0118547.161; dFKBP4; dFKBP59; fkbp59; l(2)k00424; l(2)k09010", "protein_names_uniprotkb": "FK506-binding protein 59; 5.2.1.8; PPIase; Peptidyl-prolyl cis-trans isomerase; Rotamase; dFKBP59", "protein_names_refseq": "CG4535-PB; FK506-binding protein 59kD, isoform B; FK506-binding protein FKBP59; Fkbp59-PB", "tax_id": 7227, "disease": "alcohol dependence (Disease Ontology:DOID:0050741); metabolic dysfunction and alcohol associated liver disease (Disease Ontology:DOID:0070508); major depressive disorder (Disease Ontology:DOID:1470); chronic obstructive pulmonary disease (Disease Ontology:DOID:3083); androgen insensitivity syndrome (Disease Ontology:DOID:4674); cocaine abuse (Disease Ontology:DOID:809); heroin dependence (Disease Ontology:DOID:9976)", "pathway": " (dme:Dmel_CG4535); (R-DME-3371497); (R-DME-3371568); (R-DME-8939211); (R-DME-9018519); (R-DME-9909505)", "pathway_count": 6, "publication_count": 14, "publication_id_list": "10731132;10767531;11514552;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "May have a role in phototransduction; inhibits or prevents Ca(2+) induced stimulation of the trpl ion channel., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 7, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9U4N1", "ec_number_list": "5.2.1.8;3.6.5.-;2.7.11.24;2.7.11.10;5.3.99.3", "go_molecular_function": "GO:0005528 FK506 binding;GO:0003755 peptidyl-prolyl cis-trans isomerase activity", "go_cellular_component": "GO:0016027 inaD signaling complex", "go_biological_process": "GO:0051924 regulation of calcium ion transport;GO:0006457 protein folding;GO:0050908 detection of light stimulus involved in visual perception", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "Q9VL78-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VL92-1", "uniprot_id": "CP4E3_DROME", "mass": 60883.0, "length": 526, "protein_name": "Cytochrome P450 4e3", "gene_name": "Cyp4e3", "organism": "Fruit fly", "refseq_name": "cytochrome P450 4e3", "refseq_ac": "NP_523527", "gene_names_uniprotkb": "Cyp4e3; CG4105", "gene_names_refseq": "4e3; CG4105; CYP4E3; Cyp4E3; Cyp4e3; Dmel\\CG4105; P-450; P450; cyp4e3", "protein_names_uniprotkb": "Cytochrome P450 4e3; 1.14.-.-; CYPIVE3", "protein_names_refseq": "CG4105-PA; Cyp4e3-PA; cytochrome P450 4e3; cytochrome P450-4e3; cytochrome P450", "tax_id": 7227, "disease": "Bietti crystalline corneoretinal dystrophy (Disease Ontology:DOID:0050664)", "pathway": " (dme:Dmel_CG4105); (R-DME-193144); (R-DME-196791); (R-DME-211916); (R-DME-211976)", "pathway_count": 5, "publication_count": 3, "publication_id_list": "10731132;12537572;8676871", "class_list": "", "function": "May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q24128", "ec_number_list": "1.14.-.-;1.14.15.-", "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0004497 monooxygenase activity;GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9VL92-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VL93-1", "uniprot_id": "Q9VL93_DROME", "mass": 12064.0, "length": 110, "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG13117", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform B", "refseq_ac": "NP_001260298", "gene_names_uniprotkb": "Dmel\\CG13117; BcDNA:SD27505; CG13117; Dmel_CG13117", "gene_names_refseq": "BcDNA:SD27505; CG13117; Dmel\\CG13117", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "CG13117-PB; uncharacterized protein, isoform B", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG13117)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VL93-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VLD6-1", "uniprot_id": "BOREA_DROME", "mass": 34681.0, "length": 315, "protein_name": "Borealin", "gene_name": "borr", "organism": "Fruit fly", "refseq_name": "borealin-related, isoform A", "refseq_ac": "NP_609279", "gene_names_uniprotkb": "borr; CG4454", "gene_names_refseq": "BORR; Borr; Bor; CG4454; Dmel\\CG4454; borr; dBor", "protein_names_uniprotkb": "Borealin; Aurora borealis protein; Borealin-related", "protein_names_refseq": "Borealin-related; CG4454-PA; borealin-related, isoform A; borealin; borr-PA", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG4454)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "10731132;12537569;12537572;16224046;18327897", "class_list": "", "function": "Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of embryonic mitosis. The CPC complex has essential functions at the centromere for ensuring sister chromatid cohesion, recruitment of the CPC to kinetochores, and chromosome alignment and segregation. There is no function in meiotic histone phosphorylation or spindle formation., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 8, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q8I0R3", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005938 cell cortex;GO:0051233 spindle midzone;GO:0000775 chromosome, centromeric region;GO:0000776 kinetochore", "go_biological_process": "GO:0000281 mitotic cytokinesis;GO:0051256 mitotic spindle midzone assembly;GO:0000070 mitotic sister chromatid segregation;GO:1902889 protein localization to spindle microtubule", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q9VLD6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VLL0-1", "uniprot_id": "ACSF4_DROME", "mass": 113084.0, "length": 1012, "protein_name": "Beta-alanine-activating enzyme", "gene_name": "Aasdh", "organism": "Fruit fly", "refseq_name": "Aminoadipate-semialdehyde dehydrogenase, isoform A", "refseq_ac": "NP_609230", "gene_names_uniprotkb": "Aasdh; CG13401; Dmel\\CG13401; Dmel_CG13401; U26", "gene_names_refseq": "Aasdh; CG13401; Dmel\\CG13401; U26", "protein_names_uniprotkb": "Beta-alanine-activating enzyme; 6.2.1.-; Acyl-CoA synthetase family member 4", "protein_names_refseq": "Aasdh-PA; Aminoadipate-semialdehyde dehydrogenase, isoform A; CG13401-PA; U26", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG13401)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "Covalently binds beta-alanine in an ATP-dependent manner to form a thioester bond with its phosphopantetheine group and transfers it to an, as yet, unknown acceptor. May be required for a post-translational protein modification or for post-transcriptional modification of an RNA., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q1RKX6;Q9U973", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0016878 acid-thiol ligase activity", "go_cellular_component": "", "go_biological_process": "GO:0006631 fatty acid metabolic process;GO:0019482 beta-alanine metabolic process;GO:0043041 amino acid activation for nonribosomal peptide biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VLL0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VLM5-1", "uniprot_id": "DAD1_DROME", "mass": 12526.0, "length": 112, "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1", "gene_name": "Dad1", "organism": "Fruit fly", "refseq_name": "defender against apoptotic cell death 1", "refseq_ac": "NP_609222", "gene_names_uniprotkb": "Dad1; CG13393; l(2)k12914", "gene_names_refseq": "BcDNA:RE23864; CG13393; Dad1; Dmel\\CG13393; OST; dDad1; l(2)k12914", "protein_names_uniprotkb": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1; DAD-1; Defender against apoptotic cell death 1; Defender against cell death 1; Oligosaccharyl transferase subunit DAD1", "protein_names_refseq": "CG13393-PA; Dad1-PA; defender against apoptotic cell death 1; lethal (2) k12914", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG13393)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "10731132;12537569;12537572;27693235", "class_list": "", "function": "Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity (By similarity). Probably as part of the N-glycosylation pathway, plays a role in the regulation of tissue growth and apoptosis (PubMed:27693235)., [UniProtKB, PubMed, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A1B2AKP8", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane;GO:0012505 endomembrane system;GO:0008250 oligosaccharyltransferase complex;GO:0160226 oligosaccharyltransferase complex A;GO:0160227 oligosaccharyltransferase complex B", "go_biological_process": "GO:0006915 apoptotic process;GO:0031647 regulation of protein stability;GO:0006487 protein N-linked glycosylation;GO:0180058 protein co-translational transfer of dolichol-linked oligosaccharide;GO:0180057 protein post-translational transfer of dolichol-linked oligosaccharide", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q9VLM5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VLS9-1", "uniprot_id": "LACB2_DROME", "mass": 32733.0, "length": 292, "protein_name": "Beta-lactamase-like protein 2 homolog", "gene_name": "CG12375", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": "NP_609183", "gene_names_uniprotkb": "CG12375", "gene_names_refseq": "CG12375; Dmel\\CG12375", "protein_names_uniprotkb": "Beta-lactamase-like protein 2 homolog; 3.-.-.-", "protein_names_refseq": "CG12375-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG12375)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "10731132;12537569;12537572", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q8MR51", "ec_number_list": "", "go_molecular_function": "GO:0016787 hydrolase activity;GO:0046872 metal ion binding;GO:0003727 single-stranded RNA binding;GO:0004521 RNA endonuclease activity", "go_cellular_component": "GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0031123 RNA 3'-end processing", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9VLS9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VM08-1", "uniprot_id": "GR28B_DROME", "mass": 53598.0, "length": 470, "protein_name": "Putative gustatory receptor 28b", "gene_name": "Gr28b", "organism": "Fruit fly", "refseq_name": "gustatory receptor 28b, isoform A", "refseq_ac": "NP_647614", "gene_names_uniprotkb": "Gr28b; CG13788", "gene_names_refseq": "28A3; CG13788; Dmel\\CG13788; GR28B(D); GR28B; GR28b; GRLU.2; Gr28A3; Gr28A4; Gr28b(D); Gr28b.a; Gr28b.b; Gr28b.c; Gr28b.d; Gr28b.e; Gr28bA; Gr28bB; Gr28bC; Gr28bD; Gr28bE; Gr28be; Gr28b; GrLU2; LU.2; gr28b", "protein_names_uniprotkb": "Putative gustatory receptor 28b", "protein_names_refseq": "CG13788-PA; Gr28b-PA; gustatory receptor 28A4; gustatory receptor 28b, isoform A; gustatory receptor LU.2", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG13788)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "10731132;11516643;12537572;18067151;22031876;22194978", "class_list": "", "function": "Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates (By similarity). Atypical expression also suggests nongustatory roles in the nervous system and tissues involved in proprioception, hygroreception, and other sensory modalities. It is also possible that it has chemosensory roles in the detection of internal ligands., [UniProtKB, PubMed]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0015276 ligand-gated monoatomic ion channel activity;GO:0008527 taste receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane;GO:0030424 axon;GO:0030425 dendrite;GO:0043025 neuronal cell body", "go_biological_process": "GO:0008049 male courtship behavior;GO:0006955 immune response;GO:0034220 monoatomic ion transmembrane transport;GO:0007631 feeding behavior;GO:0042742 defense response to bacterium", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q9VM08-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VM09-1", "uniprot_id": "GR28A_DROME", "mass": 51857.0, "length": 450, "protein_name": "Putative gustatory receptor 28a", "gene_name": "Gr28a", "organism": "Fruit fly", "refseq_name": "gustatory receptor 28a", "refseq_ac": "NP_523504", "gene_names_uniprotkb": "Gr28a; CG13787", "gene_names_refseq": "28A.1; CG13787; Dmel\\CG13787; GR28A.1; GR28a; Gr28A1; Gr28A2; Gr28a", "protein_names_uniprotkb": "Putative gustatory receptor 28a", "protein_names_refseq": "CG13787-PA; Gr28a-PA; gustatory receptor 28A.1; gustatory receptor 28A2; gustatory receptor 28a", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG13787)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "10731132;11516643;12537572;18067151;22031876;22194978", "class_list": "", "function": "Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates (By similarity). Atypical expression also suggests nongustatory roles in the nervous system and tissues involved in proprioception, hygroreception, and other sensory modalities. It is also possible that it has chemosensory roles in the detection of internal ligands., [UniProtKB, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0015276 ligand-gated monoatomic ion channel activity;GO:0008527 taste receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane;GO:0030424 axon;GO:0030425 dendrite;GO:0043025 neuronal cell body", "go_biological_process": "GO:0008049 male courtship behavior;GO:0007165 signal transduction;GO:0034220 monoatomic ion transmembrane transport;GO:0007635 chemosensory behavior;GO:0050909 sensory perception of taste", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q9VM09-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VM33-1", "uniprot_id": "EFGM_DROME", "mass": 83509.0, "length": 745, "protein_name": "Elongation factor G, mitochondrial", "gene_name": "mEFG1", "organism": "Fruit fly", "refseq_name": "mitochondrial translation elongation factor G 1", "refseq_ac": "NP_609105", "gene_names_uniprotkb": "mEFG1; CG4567; ico", "gene_names_refseq": "B; CG4567; Dmel\\CG4567; GFM1; G; dEF-G1; ico; l(2)27Cb; l(2)27Ea; mEFG1", "protein_names_uniprotkb": "Elongation factor G, mitochondrial; EF-Gmt; Elongation factor G 1, mitochondrial; Elongation factor G1; Protein iconoclast; dEF-G1; mEF-G 1", "protein_names_refseq": "CG4567-PA; complementation group B; complementation group G; iconoclast; lethal (2) 27Cb; lethal (2) 27Ea; mEFG1-PA; mitochondrial translation elongation factor G 1", "tax_id": 7227, "disease": "combined oxidative phosphorylation deficiency 1 (Disease Ontology:DOID:0111474)", "pathway": " (dme:Dmel_CG4567); (R-DME-5389840)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "10731132;12537572;21364917", "class_list": "", "function": "Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity). Essential during development as it acts as a retrograde signal from mitochondria to the nucleus to slow down cell proliferation if mitochondrial energy output is low., [UniProtKB, HAMAP, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q494L3", "ec_number_list": "", "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0003746 translation elongation factor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0070125 mitochondrial translational elongation", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9VM33-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VM95-1", "uniprot_id": "AATF_DROME", "mass": 55953.0, "length": 488, "protein_name": "Protein Aatf", "gene_name": "Aatf", "organism": "Fruit fly", "refseq_name": "apoptosis antagonizing transcription factor", "refseq_ac": "NP_609066", "gene_names_uniprotkb": "Aatf; CG11188", "gene_names_refseq": "AATF; Aatf; CG11188; Che-1; Dmel\\CG11188; anon-WO0118547.190; nutmeg", "protein_names_uniprotkb": "Protein Aatf; Apoptosis antagonizing transcription factor ortholog", "protein_names_refseq": "Aatf-PA; CG11188-PA; apoptosis antagonizing transcription factor ortholog; apoptosis antagonizing transcription factor; nutmeg", "tax_id": 7227, "disease": "chromosome 17q12 deletion syndrome (Disease Ontology:DOID:0060404)", "pathway": " (dme:Dmel_CG11188)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "10731132;12537569;12537572;18327897", "class_list": "", "function": "May function as a general inhibitor of the histone deacetylase HDAC1., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005730 nucleolus", "go_biological_process": "GO:0043069 negative regulation of programmed cell death;GO:0048477 oogenesis", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q9VM95-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VMC9-1", "uniprot_id": "KFA_DROME", "mass": 34911.0, "length": 300, "protein_name": "Kynurenine formamidase", "gene_name": "KFase", "organism": "Fruit fly", "refseq_name": "kynurenine formamidase, isoform B", "refseq_ac": "NP_001285676", "gene_names_uniprotkb": "KFase; CG9542; Dmel\\CG9542; Dmel_CG9542; Kf2", "gene_names_refseq": "CG9542; Dmel\\CG9542; KFase; Kf2", "protein_names_uniprotkb": "Kynurenine formamidase; 3.5.1.9; Arylformamidase; FKF; KFA; KFase; N-formylkynurenine formamidase", "protein_names_refseq": "CG9542-PB; KFase-PB; kynurenine formamidase 2; kynurenine formamidase, isoform B", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG9542)", "pathway_count": 1, "publication_count": 14, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;22690733;25589440;26109356;26109357;83140", "class_list": "", "function": "Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Required for elimination of toxic metabolites., [UniProtKB, PubMed, HAMAP, PubMed, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.5.1.9", "go_molecular_function": "GO:0004061 arylformamidase activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0019441 L-tryptophan catabolic process to kynurenine", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "Q9VMC9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VMD0-1", "uniprot_id": "DAXX_DROME", "mass": 183875.0, "length": 1659, "protein_name": "Daxx-like protein", "gene_name": "Daxx", "organism": "Fruit fly", "refseq_name": "Daxx-like protein, isoform B", "refseq_ac": "NP_001285675", "gene_names_uniprotkb": "Daxx; CG9537", "gene_names_refseq": "CG9537; DAXX; DLP; Daxx; Dmel\\CG9537; dlp", "protein_names_uniprotkb": "Daxx-like protein; DLP", "protein_names_refseq": "CG9537-PB; Daxx-PB; Daxx-like protein, isoform B", "tax_id": 7227, "disease": "oral squamous cell carcinoma (Disease Ontology:DOID:0050866); lung non-squamous non-small cell carcinoma (Disease Ontology:DOID:0080521); prostate cancer (Disease Ontology:DOID:10283); stomach cancer (Disease Ontology:DOID:10534); appendiceal neoplasm (Disease Ontology:DOID:11240); leukemia (Disease Ontology:DOID:1240); neuroendocrine tumor (Disease Ontology:DOID:169); pancreatic endocrine carcinoma (Disease Ontology:DOID:1798); islet cell tumor (Disease Ontology:DOID:1799); ovary epithelial cancer (Disease Ontology:DOID:2152); transient cerebral ischemia (Disease Ontology:DOID:224); colon adenocarcinoma (Disease Ontology:DOID:234); transitional cell carcinoma (Disease Ontology:DOID:2671); clear cell adenocarcinoma (Disease Ontology:DOID:4468)", "pathway": " (dme:Dmel_CG9537)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "10731132;12537572;17933869;23593018;28320872", "class_list": "", "function": "Transcription regulator (PubMed:17933869, PubMed:23593018). Acts as a histone chaperone that facilitates deposition of histone H3.3 (PubMed:28320872). Has a role in chromatin remodeling together with asf1 and XNP (PubMed:28320872). Has role in the transcriptional apoptotic response to oxidative and UV stress (PubMed:17933869, PubMed:23593018)., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 14, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "Q6NNF9", "ec_number_list": "", "go_molecular_function": "GO:0042393 histone binding;GO:0003712 transcription coregulator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0005694 chromosome", "go_biological_process": "GO:0006979 response to oxidative stress;GO:0006355 regulation of DNA-templated transcription;GO:0006915 apoptotic process;GO:0045893 positive regulation of DNA-templated transcription;GO:0042981 regulation of apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q9VMD0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VMG0-1", "uniprot_id": "DNAT2_DROME", "mass": 24360.0, "length": 216, "protein_name": "Arylalkylamine N-acetyltransferase-like 2", "gene_name": "AANATL2", "organism": "Fruit fly", "refseq_name": "arylalkylamine N-acetyltransferase-like 2, isoform B", "refseq_ac": "NP_001285667", "gene_names_uniprotkb": "AANATL2; CG9486; aaNAT2", "gene_names_refseq": "AANAT2; AANATL2; CG9486; DmAANATL2; Dmel\\CG9486; aaNAT2", "protein_names_uniprotkb": "Arylalkylamine N-acetyltransferase-like 2; 2.3.1.87; 2.3.2.-; AANAT2; Arylalkylamine N-acyltransferase-like 2", "protein_names_refseq": "AANATL2-PB; CG9486-PB; arylalkylamine N-acetyltransferase 2; arylalkylamine N-acetyltransferase-like 2, isoform B; arylalkylamine N-acetyltransferase-like 2; arylalkylamine N-acyltransferase-like 2", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG9486)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "10731132;11098219;12537572;24444601;26476413;31385627;40245499", "class_list": "", "function": "Catalyzes the formation of long-chain N-acylserotonins and N-acyldopamines, which are important cellular signaling lipids (PubMed:24444601, PubMed:31385627). Catalyzes in vitro the formation of various N-acetyl-2-arylethylamines such as N-acetyltryptamine and melatonin (PubMed:11098219, PubMed:26476413)., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 6, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q4V4G0", "ec_number_list": "2.3.1.87;2.3.2.-", "go_molecular_function": "GO:0004059 aralkylamine N-acetyltransferase activity;GO:0016410 N-acyltransferase activity;GO:0008080 N-acetyltransferase activity", "go_cellular_component": "", "go_biological_process": "GO:0006631 fatty acid metabolic process;GO:0030187 melatonin biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "Q9VMG0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VMH7-1", "uniprot_id": "EFM5_DROME", "mass": 26043.0, "length": 223, "protein_name": "Protein-lysine N-methyltransferase CG9154", "gene_name": "CG9154", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform B", "refseq_ac": "NP_001285662", "gene_names_uniprotkb": "CG9154", "gene_names_refseq": "CG9154; Dmel\\CG9154", "protein_names_uniprotkb": "Protein-lysine N-methyltransferase CG9154; 2.1.1.-", "protein_names_refseq": "CG9154-PB; uncharacterized protein, isoform B", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG9154); (R-DME-8876725)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "10731132;12537569;12537572", "class_list": "", "function": "S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that methylates elongation factor 1-alpha., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q95SB4", "ec_number_list": "2.1.1.-", "go_molecular_function": "GO:0003676 nucleic acid binding;GO:0016279 protein-lysine N-methyltransferase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0032259 methylation", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9VMH7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VML1-1", "uniprot_id": "DSF_DROME", "mass": 74053.0, "length": 691, "protein_name": "Protein dissatisfaction", "gene_name": "dsf", "organism": "Fruit fly", "refseq_name": "dissatisfaction, isoform B", "refseq_ac": "NP_001260109", "gene_names_uniprotkb": "dsf; CG9019; NR2E4", "gene_names_refseq": "CG9019; DSF; Dmel\\CG9019; Dsf; NR2E4; dsf", "protein_names_uniprotkb": "Protein dissatisfaction; Nuclear receptor subfamily 2 group E member 4", "protein_names_refseq": "CG9019-PB; dissatisfaction, isoform B; dissatisfaction; dsf-PB", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG9019)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "10731132;11977984;12537572;9023356;9883729", "class_list": "", "function": "Orphan receptor that binds DNA as a monomer to hormone response elements (HRE) containing an extended core motif half-site sequence 5'-AAGTCA-3' (PubMed:11977984). Acts as a transcriptional repressor (PubMed:11977984). In both females and males, functions downstream of tra2 to regulate the development and function of certain sex-specific abdominal neurons, and likely regulates the development and/or function of the nervous system that controls courtship behaviors involved in the recognition and response of adults to appropriate sexual partners (PubMed:11977984, PubMed:9023356, PubMed:9883729). In males, promotes abdominal motor neuronal innervation of the ventral muscles of abdominal segment 5 which is required for correct abdominal curling during copulation (PubMed:9023356, PubMed:9883729). In females, also promotes abdominal motor neuronal innervation but on the uterine muscles which is required for egg laying (PubMed:9023356, PubMed:9883729)., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 9, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "O96680", "ec_number_list": "", "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0008270 zinc ion binding;GO:0003707 nuclear steroid receptor activity;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0007530 sex determination;GO:0008049 male courtship behavior;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0007617 mating behavior", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q9VML1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VMQ5-1", "uniprot_id": "COQ6_DROME", "mass": 51994.0, "length": 477, "protein_name": "Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial", "gene_name": "Coq6", "organism": "Fruit fly", "refseq_name": "coenzyme Q6", "refseq_ac": "NP_608934", "gene_names_uniprotkb": "Coq6; CG7277", "gene_names_refseq": "CG7277; Coq6; Dmel\\CG7277", "protein_names_uniprotkb": "Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; 1.14.15.45; 1.14.15.46; 2-methoxy-6-polyprenolphenol 4-hydroxylase", "protein_names_refseq": "CG7277-PA; Coq6-PA; coenzyme Q6", "tax_id": 7227, "disease": "primary coenzyme Q10 deficiency 6 (Disease Ontology:DOID:0070243); nephrotic syndrome (Disease Ontology:DOID:1184); schwannomatosis (Disease Ontology:DOID:3204)", "pathway": " (dme:Dmel_CG7277); (R-DME-2142789)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "10731132;12537569;12537572", "class_list": "", "function": "FAD-dependent monooxygenase required for two non-consecutive steps during ubiquinone biosynthesis. Required for the C5-ring hydroxylation during ubiquinone biosynthesis by catalyzing the hydroxylation of 4-hydroxy-3-(all-trans-polyprenyl)benzoic acid to 3,4-dihydroxy-5-(all-trans-polyprenyl)benzoic acid. Also acts downstream of coq4, for the C1-hydroxylation during ubiquinone biosynthesis by catalyzing the hydroxylation of 2-methoxy-6-(all-trans-polyprenyl)phenol to 2-methoxy-6-(all-trans-polyprenyl)benzene-1,4-diol. The electrons required for the hydroxylation reaction are funneled indirectly to Coq6 from NADPH via a ferredoxin/ferredoxin reductase system., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.1.1.-;2.1.1.114;2.1.1.64;1.14.15.45;1.14.15.46;4.1.1.130;2.1.1.201;1.14.99.60", "go_molecular_function": "GO:0071949 FAD binding;GO:0016491 oxidoreductase activity;GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen;GO:0106364 4-hydroxy-3-all-trans-polyprenylbenzoate oxygenase activity;GO:0120538 2-methoxy-6-polyprenolphenol 4-hydroxylase activity", "go_cellular_component": "GO:0031314 extrinsic component of mitochondrial inner membrane;GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane;GO:0110142 ubiquinone biosynthesis complex", "go_biological_process": "GO:0006744 ubiquinone biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9VMQ5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VMQ7-1", "uniprot_id": "ELP4_DROME", "mass": 48712.0, "length": 437, "protein_name": "Elongator complex protein 4", "gene_name": "Elp4", "organism": "Fruit fly", "refseq_name": "elongator complex protein 4, isoform B", "refseq_ac": "NP_001285628", "gene_names_uniprotkb": "Elp4; CG6907", "gene_names_refseq": "CG6907; Dmel\\CG6907; Elp4", "protein_names_uniprotkb": "Elongator complex protein 4", "protein_names_refseq": "CG6907-PB; Elp4-PB; elongator complex protein 4, isoform B", "tax_id": 7227, "disease": "aniridia (Disease Ontology:DOID:12271)", "pathway": " (dme:Dmel_CG6907)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "10731132;12537569;12537572;18327897;36302967", "class_list": "", "function": "Component of the elongator complex, which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine) (PubMed:36302967). The elongator complex catalyzes the formation of carboxymethyluridine in the wobble base at position 34 in tRNAs (PubMed:36302967). Binding by the elongator complex stabilizes microtubules and promotes their growth (PubMed:36302967). This induces central spindle asymmetry, promoting polarized signaling endosome trafficking during asymmetric cell division and cell fate assignation of sensory organ precursor cells (PubMed:36302967)., [UniProtKB, UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "X2J4N6", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005819 spindle;GO:0005874 microtubule;GO:0008023 transcription elongation factor complex;GO:0033588 elongator holoenzyme complex", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0006417 regulation of translation;GO:0002098 tRNA wobble uridine modification;GO:0061867 establishment of mitotic spindle asymmetry", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q9VMQ7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VMS7-1", "uniprot_id": "C4AC3_DROME", "mass": 58821.0, "length": 509, "protein_name": "Probable cytochrome P450 4ac3", "gene_name": "Cyp4ac3", "organism": "Fruit fly", "refseq_name": "cytochrome P450 4ac3", "refseq_ac": "NP_608918", "gene_names_uniprotkb": "Cyp4ac3; CG14031", "gene_names_refseq": "4ac3; CG14031; CYP4AC3; Cyp4AC3; Cyp4ac3; Dmel\\CG14031", "protein_names_uniprotkb": "Probable cytochrome P450 4ac3; 1.14.-.-; CYPIVAC3", "protein_names_refseq": "CG14031-PA; Cyp4ac3-PA; cytochrome P450 4ac3; cytochrome P450", "tax_id": 7227, "disease": "Bietti crystalline corneoretinal dystrophy (Disease Ontology:DOID:0050664)", "pathway": " (dme:Dmel_CG14031); (R-DME-193144); (R-DME-196791); (R-DME-211916); (R-DME-211976)", "pathway_count": 5, "publication_count": 3, "publication_id_list": "10731132;12537569;12537572", "class_list": "", "function": "May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.14.-.-;1.14.15.-", "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0004497 monooxygenase activity;GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9VMS7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VMS9-1", "uniprot_id": "C4AC1_DROME", "mass": 59186.0, "length": 509, "protein_name": "Probable cytochrome P450 4ac1", "gene_name": "Cyp4ac1", "organism": "Fruit fly", "refseq_name": "cytochrome P450 4ac1", "refseq_ac": "NP_608916", "gene_names_uniprotkb": "Cyp4ac1; CG14032", "gene_names_refseq": "4ac1; CG14032; CYP4ac1; Cyp4AC1; Cyp4ac1; Dmel\\CG14032; cyp4ac1", "protein_names_uniprotkb": "Probable cytochrome P450 4ac1; 1.14.-.-; CYPIVAC1", "protein_names_refseq": "CG14032-PA; Cyp4ac1-PA; cytochrome P450 4ac1", "tax_id": 7227, "disease": "Bietti crystalline corneoretinal dystrophy (Disease Ontology:DOID:0050664)", "pathway": " (dme:Dmel_CG14032); (R-DME-193144); (R-DME-196791); (R-DME-211916); (R-DME-211976)", "pathway_count": 5, "publication_count": 3, "publication_id_list": "10731132;12537569;12537572", "class_list": "", "function": "May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.14.-.-;1.14.15.-", "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0004497 monooxygenase activity;GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9VMS9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VMT4-1", "uniprot_id": "Q9VMT4_DROME", "mass": 58477.0, "length": 509, "protein_name": "Rab-GAP TBC domain-containing protein", "gene_name": "Dmel\\CG7742", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform D", "refseq_ac": "NP_001285615", "gene_names_uniprotkb": "Dmel\\CG7742; CG7742; Dmel_CG7742", "gene_names_refseq": "CG7742; Dmel\\CG7742", "protein_names_uniprotkb": "Rab-GAP TBC domain-containing protein", "protein_names_refseq": "CG7742-PD; uncharacterized protein, isoform D", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG7742)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005096 GTPase activator activity", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VMT4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VMY9-1", "uniprot_id": "GUAD_DROME", "mass": 48885.0, "length": 448, "protein_name": "Guanine deaminase", "gene_name": "DhpD", "organism": "Fruit fly", "refseq_name": "dihydropterin deaminase", "refseq_ac": "NP_649439", "gene_names_uniprotkb": "DhpD; CG18143", "gene_names_refseq": "CG18143; DhpD; Dmel\\CG18143", "protein_names_uniprotkb": "Guanine deaminase; 3.5.4.-; 3.5.4.3; Dihydropterin deaminase", "protein_names_refseq": "CG18143-PA; DhpD-PA; dihydropterin deaminase", "tax_id": 7227, "disease": "stomach cancer (Disease Ontology:DOID:10534)", "pathway": " (dme:Dmel_CG18143); (R-DME-74259)", "pathway_count": 2, "publication_count": 4, "publication_id_list": "10731132;12537569;12537572;19567870", "class_list": "", "function": "Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia. Also has 7,8-dihydropterin deaminase activity, which plays a role in synthesis of the red eye pigment aurodrosopterin., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.5.4.3;3.5.4.-", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0008892 guanine deaminase activity;GO:0004153 dihydropterin deaminase activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0046098 guanine metabolic process;GO:0006726 eye pigment biosynthetic process;GO:0006147 guanine catabolic process;GO:0051067 dihydropteridine metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q9VMY9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VN14-1", "uniprot_id": "CONT_DROME", "mass": 158239.0, "length": 1390, "protein_name": "Contactin", "gene_name": "Cont", "organism": "Fruit fly", "refseq_name": "contactin", "refseq_ac": "NP_649461", "gene_names_uniprotkb": "Cont; CG1084", "gene_names_refseq": "CG1084; CONT; CT1481; Cont; D-Axonin; DCONT; Dmel\\CG1084; cont", "protein_names_uniprotkb": "Contactin", "protein_names_refseq": "CG1084-PA; Cont-PA; D-Contactin; contactin; dcontactin", "tax_id": 7227, "disease": "Compton-North congenital myopathy (Disease Ontology:DOID:0080101); familial adult myoclonic epilepsy 5 (Disease Ontology:DOID:0111691); high grade glioma (Disease Ontology:DOID:3070); T-cell adult acute lymphocytic leukemia (Disease Ontology:DOID:5602); lung disease (Disease Ontology:DOID:850)", "pathway": " (dme:Dmel_CG1084); (R-DME-1474228); (R-DME-210991); (R-DME-216083); (R-DME-428542); (R-DME-433692); (R-DME-9749641)", "pathway_count": 7, "publication_count": 7, "publication_id_list": "10731132;12537569;12537572;15459097;17893096;19349973;20935638", "class_list": "", "function": "Required for organization of septate junctions and paracellular barrier functions. Septate junctions, which are the equivalent of vertebrates tight junctions, are characterized by regular arrays of transverse structures that span the intermembrane space and form a physical barrier to diffusion., [UniProtKB, PubMed]", "predicted_glycosites": 10, "predicted_n_glycosites": 9, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 3, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 3, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 3, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 13, "binding_glycan_count": 0, "secondary_ac_list": "Q5BI91;Q8SWW3", "ec_number_list": "", "go_molecular_function": "GO:0098632 cell-cell adhesion mediator activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0030424 axon;GO:0005918 septate junction;GO:0098552 side of membrane", "go_biological_process": "GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007411 axon guidance;GO:0008366 axon ensheathment;GO:0070593 dendrite self-avoidance;GO:0060857 establishment of glial blood-brain barrier", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "Q9VN14-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VN50-1", "uniprot_id": "EI3F1_DROME", "mass": 31105.0, "length": 280, "protein_name": "Eukaryotic translation initiation factor 3 subunit F-1", "gene_name": "eIF3f1", "organism": "Fruit fly", "refseq_name": "eukaryotic translation initiation factor 3 subunit f1", "refseq_ac": "NP_649489", "gene_names_uniprotkb": "eIF3f1; CG9769; eIF3-S5-1", "gene_names_refseq": "CG9769; Dmel\\CG9769; Q9VN50; eIF3-S5; eIF3f1; eIF3f; eif3f", "protein_names_uniprotkb": "Eukaryotic translation initiation factor 3 subunit F-1; Eukaryotic translation initiation factor 3 subunit 5-1; eIF3f-1", "protein_names_refseq": "CG9769-PA; eIF3f1-PA; eukaryotic translation initiation factor 3 subunit f1", "tax_id": 7227, "disease": "autosomal recessive intellectual developmental disorder 67 (Disease Ontology:DOID:0081228); type 2 diabetes mellitus (Disease Ontology:DOID:9352)", "pathway": " (dme:Dmel_CG9769); (R-DME-156827); (R-DME-72649); (R-DME-72689); (R-DME-72695); (R-DME-72702)", "pathway_count": 6, "publication_count": 3, "publication_id_list": "10731132;12537569;12537572", "class_list": "", "function": "Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003743 translation initiation factor activity;GO:0031369 translation initiation factor binding;GO:0140492 metal-dependent deubiquitinase activity", "go_cellular_component": "GO:0016282 eukaryotic 43S preinitiation complex;GO:0033290 eukaryotic 48S preinitiation complex;GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m;GO:0005852 eukaryotic translation initiation factor 3 complex", "go_biological_process": "GO:0050829 defense response to Gram-negative bacterium;GO:0045747 positive regulation of Notch signaling pathway;GO:0006413 translational initiation;GO:0001732 formation of cytoplasmic translation initiation complex;GO:0061059 positive regulation of peptidoglycan recognition protein signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9VN50-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VN93-1", "uniprot_id": "CATF_DROME", "mass": 68961.0, "length": 614, "protein_name": "Cathepsin F", "gene_name": "CtsF", "organism": "Fruit fly", "refseq_name": "cathepsin F, isoform B", "refseq_ac": "NP_649521", "gene_names_uniprotkb": "CtsF; CG12163", "gene_names_refseq": "CG12163; CTSF; Cts8; Cts9; CtsF; Dmel\\CG12163; anon-WO0118547.305", "protein_names_uniprotkb": "Cathepsin F; 3.4.22.41; Cysteine proteinase CtsF", "protein_names_refseq": "CG12163-PB; CtsF-PB; cathepsin F, isoform B", "tax_id": 7227, "disease": "neuronal ceroid lipofuscinosis 13 (Disease Ontology:DOID:0110727)", "pathway": " (dme:Dmel_CG12163); (R-DME-114608); (R-DME-2132295)", "pathway_count": 3, "publication_count": 4, "publication_id_list": "10731132;12537569;12537572;12593804", "class_list": "", "function": "May have a role in autophagic cell death., [UniProtKB, PubMed]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "Q867H7;Q9VN92", "ec_number_list": "3.4.22.-;3.4.22.15;3.4.23.-;3.4.22.41;3.4.-.-", "go_molecular_function": "GO:0004197 cysteine-type endopeptidase activity;GO:0008234 cysteine-type peptidase activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005764 lysosome;GO:0098595 perivitelline space;GO:0045169 fusome", "go_biological_process": "GO:0051603 proteolysis involved in protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q9VN93-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VNH6-1", "uniprot_id": "EXOC4_DROME", "mass": 111667.0, "length": 985, "protein_name": "Exocyst complex component 4", "gene_name": "Sec8", "organism": "Fruit fly", "refseq_name": "secretory 8", "refseq_ac": "NP_730996", "gene_names_uniprotkb": "Sec8; CG2095", "gene_names_refseq": "CG2095; Dmel\\CG2095; Sec8p; Sec8; dsec8; fun; sec8", "protein_names_uniprotkb": "Exocyst complex component 4; Exocyst complex component Sec8", "protein_names_refseq": "CG2095-PA; Sec8 ortholog; Sec8-PA; funnel cakes; secretory 8", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG2095); (R-DME-264876); (R-DME-5620916)", "pathway_count": 3, "publication_count": 5, "publication_id_list": "10731132;12537569;12537572;16351720;18327897", "class_list": "", "function": "Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Involved in regulation of synaptic microtubule formation, and also regulation of synaptic growth and glutamate receptor trafficking. Does not appear to be required for basal neurotransmission., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q5ECP5", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0032584 growth cone membrane;GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0016020 membrane;GO:0045202 synapse", "go_biological_process": "GO:0016080 synaptic vesicle targeting;GO:0007009 plasma membrane organization;GO:0015031 protein transport;GO:0050803 regulation of synapse structure or activity;GO:0007268 chemical synaptic transmission", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q9VNH6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VNJ5-1", "uniprot_id": "DISP_DROME", "mass": 138979.0, "length": 1218, "protein_name": "Protein dispatched", "gene_name": "disp", "organism": "Fruit fly", "refseq_name": "dispatched", "refseq_ac": "NP_524734", "gene_names_uniprotkb": "disp; CG2019", "gene_names_refseq": "CG2019; Disp; Dmel\\CG2019; anon-WO0146227.1; disp", "protein_names_uniprotkb": "Protein dispatched", "protein_names_refseq": "CG2019-PA; disp-PA; dispatched", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG2019); (R-DME-209471)", "pathway_count": 2, "publication_count": 17, "publication_id_list": "10549295;10619433;10731132;11395778;11486055;11861468;12372301;12537569;12537572;12586063;14729575;15189162;15563523;15875013;17893096;18198278;8824192", "class_list": "", "function": "Segment polarity protein which functions in hedgehog (Hh) signaling. Regulates the trafficking and the release of cholesterol-modified hedgehog protein from cells of the posterior compartment (P cells) and is hence required for the effective production of the Hh signal., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 8, "predicted_n_glycosites": 7, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 2, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 2, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 2, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 4, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 10, "binding_glycan_count": 0, "secondary_ac_list": "B6IDI9;Q5U173;Q8SY40;Q9U477", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane;GO:0035230 cytoneme", "go_biological_process": "GO:0007224 smoothened signaling pathway;GO:0008354 germ cell migration;GO:0007225 patched ligand maturation;GO:0007367 segment polarity determination;GO:0035222 wing disc pattern formation", "synthesized_glycan_count": 0, "hit_score": 2.0, "record_id": "Q9VNJ5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VNL4-1", "uniprot_id": "GRCR1_DROME", "mass": 50164.0, "length": 454, "protein_name": "Glutaredoxin domain-containing cysteine-rich protein CG31559", "gene_name": "CG31559", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": "NP_731045", "gene_names_uniprotkb": "CG31559", "gene_names_refseq": "31559; CG11461; CG15584; CG31559; Dmel\\CG31559", "protein_names_uniprotkb": "Glutaredoxin domain-containing cysteine-rich protein CG31559", "protein_names_refseq": "CG31559-PA; uncharacterized protein", "tax_id": 7227, "disease": "autosomal recessive nonsyndromic deafness 25 (Disease Ontology:DOID:0110483)", "pathway": " (dme:Dmel_CG31559)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "10731132;12537572", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q8SZ66", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "GO:0007605 sensory perception of sound", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q9VNL4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VNV3-1", "uniprot_id": "DDX1_DROME", "mass": 80869.0, "length": 727, "protein_name": "ATP-dependent RNA helicase Ddx1", "gene_name": "Ddx1", "organism": "Fruit fly", "refseq_name": "Dead-box-1", "refseq_ac": "NP_524212", "gene_names_uniprotkb": "Ddx1; CG9054", "gene_names_refseq": "CG9054; DDX1; Dbp79E; Ddx1; DmDDX1; DmRH12; Dmel\\CG9054; anon-79E", "protein_names_uniprotkb": "ATP-dependent RNA helicase Ddx1; 3.6.4.13; DEAD box protein 1", "protein_names_refseq": "CG9054-PA; Ddx1-PA; Dead-box-1", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG9054)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "10731132;12537569;12537572;8666277", "class_list": "", "function": "Acts as an ATP-dependent RNA helicase, able to unwind both RNA-RNA and RNA-DNA duplexes. Possesses 5' single-stranded RNA overhang nuclease activity. It is also an accessory subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "O61663;Q24131", "ec_number_list": "3.6.4.13;7.2.2.-;3.6.4.-;3.6.4.10;3.6.4.6;3.6.4.12;5.6.2.4;5.6.2.5;2.7.4.3;5.6.2.3;3.1.-.-;3.6.1.15;3.-.-.-;5.6.1.1;2.7.11.1;3.6.-.-;5.6.2.-", "go_molecular_function": "GO:0033677 DNA/RNA helicase activity;GO:0003682 chromatin binding;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0004527 exonuclease activity", "go_cellular_component": "GO:0005634 nucleus;GO:0072669 tRNA-splicing ligase complex", "go_biological_process": "GO:0007283 spermatogenesis;GO:0008033 tRNA processing;GO:0006302 double-strand break repair;GO:0048477 oogenesis;GO:0001700 embryonic development via the syncytial blastoderm", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q9VNV3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VNZ8-1", "uniprot_id": "ALS2_DROME", "mass": 165886.0, "length": 1486, "protein_name": "Alsin homolog", "gene_name": "Als2", "organism": "Fruit fly", "refseq_name": "amyotrophic lateral sclerosis 2", "refseq_ac": "NP_649347", "gene_names_uniprotkb": "Als2; CG7158", "gene_names_refseq": "ALS2; Als2; CG7158; Dmel\\CG7158; dALS2", "protein_names_uniprotkb": "Alsin homolog; Amyotrophic lateral sclerosis 2 protein homolog", "protein_names_refseq": "Als2-PA; CG7158-PA; alsin; amyotrophic lateral sclerosis 2 ortholog; amyotrophic lateral sclerosis 2", "tax_id": 7227, "disease": "amyotrophic lateral sclerosis type 2 (Disease Ontology:DOID:0060194); amyotrophic lateral sclerosis (Disease Ontology:DOID:332)", "pathway": " (dme:Dmel_CG7158); (R-DME-8876198); (R-DME-9013149)", "pathway_count": 3, "publication_count": 4, "publication_id_list": "10731132;12537569;12537572;24702731", "class_list": "", "function": "Has guanine nucleotide exchange factor (GEF) activity towards Rab5. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab5 into its active GTP-bound form., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005096 GTPase activator activity;GO:0005085 guanyl-nucleotide exchange factor activity;GO:0031267 small GTPase binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0031982 vesicle", "go_biological_process": "GO:0032483 regulation of Rab protein signal transduction;GO:0045022 early endosome to late endosome transport;GO:0016197 endosomal transport;GO:0035011 melanotic encapsulation of foreign target", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q9VNZ8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VP61-1", "uniprot_id": "ACSA_DROME", "mass": 75946.0, "length": 670, "protein_name": "Acetyl-coenzyme A synthetase", "gene_name": "AcCoAS", "organism": "Fruit fly", "refseq_name": "acetyl coenzyme A synthase, isoform D", "refseq_ac": "NP_001014599", "gene_names_uniprotkb": "AcCoAS; CG9390", "gene_names_refseq": "ACS; ACeCS1; AcCoAS; AcCoAs; BEST:GH28401; CG9390; Dmel\\CG9390; acs; dACS", "protein_names_uniprotkb": "Acetyl-coenzyme A synthetase; 6.2.1.1; ACS; AceCS; Acetate--CoA ligase; Acetyl-CoA synthetase; Acyl-activating enzyme", "protein_names_refseq": "Ac CoA synthase; AcCoA synthetase; AcCoAS-PD; Acetyl-CoA synthase; Acetyl-CoA sythase; AcetylCoA synthase; CG9390-PD; acetate-coenzyme A ligase; acetyl CoA synthase; acetyl CoA synthetase; acetyl coenzyme A synthase, isoform D; acetyl coenzyme A synthase; acetyl-CoA synthetase; acetyl-coenzyme A synthase", "tax_id": 7227, "disease": "orofacial cleft (Disease Ontology:DOID:0050567); morbid obesity (Disease Ontology:DOID:11981); alcohol use disorder (Disease Ontology:DOID:1574); lymphangioleiomyomatosis (Disease Ontology:DOID:3319)", "pathway": " (dme:Dmel_CG9390); (R-DME-71384)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "10731132;12537569;12537572", "class_list": "", "function": "Activates acetate so that it can be used for lipid synthesis or for energy generation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "F3YDG9;Q24226;Q59E09;Q8IH30;Q9VP60", "ec_number_list": "6.2.1.1;6.2.1.17", "go_molecular_function": "GO:0005524 ATP binding;GO:0016208 AMP binding;GO:0003987 acetate-CoA ligase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0048149 behavioral response to ethanol;GO:0006085 acetyl-CoA biosynthetic process;GO:0045494 photoreceptor cell maintenance;GO:0019427 acetyl-CoA biosynthetic process from acetate", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9VP61-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VPC0-1", "uniprot_id": "KP58_DROME", "mass": 108838.0, "length": 952, "protein_name": "Serine/threonine-protein kinase PITSLRE", "gene_name": "Pitslre", "organism": "Fruit fly", "refseq_name": "pitslre, isoform E", "refseq_ac": "NP_001246851", "gene_names_uniprotkb": "Pitslre; CG4268", "gene_names_refseq": "CG4268; Dmel\\CG4268; Gat; Gta; PITSLRE; PitsIre; Pitslre; cdk11; group 3; pitslre", "protein_names_uniprotkb": "Serine/threonine-protein kinase PITSLRE; 2.7.11.22; Cell division cycle 2-like", "protein_names_refseq": "CG4268-PE; Galactosyltransferase-associated kinase-like; Gat-like; PITSLRE kinase; PITSLRE; Pitslre-PE; pitslre, isoform E", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG4268)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "10731132;12537569;12537572;1378625;18327897;8930898", "class_list": "", "function": "Acts as a negative regulator of the normal cell cycle progression. May function in regulating proliferation by the phosphorylation and subsequent plasma membrane targeting of galactosyltransferase (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q5U100;Q8MQR7;Q94889;Q9TXB3", "ec_number_list": "2.7.11.17;2.7.11.1;2.7.11.13;2.7.11.24;2.7.10.1;2.7.11.22;2.7.11.21;2.7.10.2;5.6.1.8;2.7.11.11;2.7.11.23;2.7.12.1;2.7.11.25;2.7.11.12;2.7.12.2;2.7.11.39", "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0004713 protein tyrosine kinase activity;GO:0005524 ATP binding;GO:0004693 cyclin-dependent protein serine/threonine kinase activity;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0002225 positive regulation of antimicrobial peptide production;GO:0045752 positive regulation of Toll signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q9VPC0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VPH8-1", "uniprot_id": "RBBP5_DROME", "mass": 54406.0, "length": 489, "protein_name": "Retinoblastoma-binding protein 5 homolog", "gene_name": "Rbbp5", "organism": "Fruit fly", "refseq_name": "retinoblastoma binding protein 5", "refseq_ac": "NP_649209", "gene_names_uniprotkb": "Rbbp5; CG5585", "gene_names_refseq": "CG5585; Dmel\\CG5585; RBBP5; RbBP5; Rbbp5; dRbbp5; rbbp5", "protein_names_uniprotkb": "Retinoblastoma-binding protein 5 homolog", "protein_names_refseq": "CG5585-PA; Rbbp5-PA; Retinoblastoma-binding; protein 5; retinoblastoma binding protein 5", "tax_id": 7227, "disease": "congenital heart disease (Disease Ontology:DOID:1682)", "pathway": " (dme:Dmel_CG5585); (R-DME-201722); (R-DME-8936459); (R-DME-8951664); (R-DME-9772755); (R-DME-9909649)", "pathway_count": 6, "publication_count": 5, "publication_id_list": "10731132;12537569;12537572;21694722;21875999", "class_list": "", "function": "Component of the SET1 complex that specifically di- and trimethylates 'Lys-4' of histone H3 and of the MLL3/4 complex which also methylates histone H3 'Lys-4'., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "B3DMX7", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0044666 MLL3/4 complex;GO:0048188 Set1C/COMPASS complex;GO:0044665 MLL1/2 complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0007507 heart development;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0006325 chromatin organization;GO:0032968 positive regulation of transcription elongation by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q9VPH8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VPN2-1", "uniprot_id": "AMNLS_DROME", "mass": 56864.0, "length": 505, "protein_name": "Protein amnionless", "gene_name": "Amnionless", "organism": "Fruit fly", "refseq_name": "amnionless, isoform B", "refseq_ac": "NP_001259813", "gene_names_uniprotkb": "Amnionless; CG11592", "gene_names_refseq": "Amnionless; Amn; BEST:CK02467; CG11592; CK02467; Dmel\\CG11592; dAMN; dAmn", "protein_names_uniprotkb": "Protein amnionless", "protein_names_refseq": "Amnionless-PB; CG11592-PB; amnionless ortholog; amnionless, isoform B", "tax_id": 7227, "disease": "cardiomyopathy (Disease Ontology:DOID:0050700); megaloblastic anemia (Disease Ontology:DOID:13382); kidney disease (Disease Ontology:DOID:557)", "pathway": " (dme:Dmel_CG11592); (R-DME-9758881)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "10731132;12537572;23264686", "class_list": "", "function": "Required in the nephrocyte for normal uptake of proteins and elimination of toxins, and for maintenance of endocytic trafficking structures. May function together with Cubn., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0038024 cargo receptor activity", "go_cellular_component": "GO:0016020 membrane;GO:0043235 receptor complex;GO:0016324 apical plasma membrane;GO:0030139 endocytic vesicle", "go_biological_process": "GO:0097017 renal protein absorption;GO:0015031 protein transport;GO:0006898 receptor-mediated endocytosis;GO:0008104 intracellular protein localization;GO:0072583 clathrin-dependent endocytosis", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9VPN2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VPQ2-1", "uniprot_id": "DJSHV_DROME", "mass": 40212.0, "length": 354, "protein_name": "DnaJ homolog shv", "gene_name": "shv", "organism": "Fruit fly", "refseq_name": "shriveled", "refseq_ac": "NP_608525", "gene_names_uniprotkb": "shv; CG4164", "gene_names_refseq": "CG4164; Dmel\\CG4164; shv", "protein_names_uniprotkb": "DnaJ homolog shv; Protein shriveled", "protein_names_refseq": "CG4164-PA; shriveled; shv-PA", "tax_id": 7227, "disease": "polycystic kidney disease 6 (Disease Ontology:DOID:0060951)", "pathway": " (dme:Dmel_CG4164)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "10731132;12537569;12537572;27191715", "class_list": "", "function": "Maintains stem cell niche architecture in the testes. Activates an extracellular integrin beta-PS pathway which regulates DE-cadherin (shg) levels in somatic hub cells, and is essential for maintaining the number of germline stem cells and the structure and localization of hub cells., [UniProtKB, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0051082 unfolded protein binding;GO:0048018 receptor ligand activity;GO:0051787 misfolded protein binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005634 nucleus;GO:0005783 endoplasmic reticulum;GO:0005886 plasma membrane;GO:0031594 neuromuscular junction", "go_biological_process": "GO:0007155 cell adhesion;GO:0006457 protein folding;GO:0090129 positive regulation of synapse maturation;GO:0051604 protein maturation;GO:2001046 positive regulation of integrin-mediated signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q9VPQ2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VPS5-1", "uniprot_id": "CH60B_DROME", "mass": 68637.0, "length": 648, "protein_name": "60 kDa heat shock protein homolog 1, mitochondrial", "gene_name": "Hsp60B", "organism": "Fruit fly", "refseq_name": "heat shock protein 60B", "refseq_ac": "NP_524925", "gene_names_uniprotkb": "Hsp60B; CG2830", "gene_names_refseq": "152031_at; CG2830; Dm21D; Dmel\\CG2830; HSP60B; Hsp60B; Hsp60b; Hsp60; Hsp64; anon-WO0140519.61; hsp60B; ms(2)06619; ms(2)21D", "protein_names_uniprotkb": "60 kDa heat shock protein homolog 1, mitochondrial; 60 kDa chaperonin; CPN60; HSP-60; Heat shock protein 60; Hsp60", "protein_names_refseq": "CG2830-PA; Hsp 60 related; Hsp60B-PA; heat shock protein 60 related; heat shock protein 60B; male sterile(2)21D", "tax_id": 7227, "disease": "hypomyelinating leukodystrophy 4 (Disease Ontology:DOID:0060789); hereditary spastic paraplegia 13 (Disease Ontology:DOID:0110766); glucose intolerance (Disease Ontology:DOID:10603); Alzheimer's disease (Disease Ontology:DOID:10652); hypertension (Disease Ontology:DOID:10763); hydrocephalus (Disease Ontology:DOID:10908); varicocele (Disease Ontology:DOID:12337); autistic disorder (Disease Ontology:DOID:12849); low tension glaucoma (Disease Ontology:DOID:13544); Down syndrome (Disease Ontology:DOID:14250); Parkinson's disease (Disease Ontology:DOID:14330); cystic fibrosis (Disease Ontology:DOID:1485); arteriosclerosis (Disease Ontology:DOID:2349); hereditary spastic paraplegia (Disease Ontology:DOID:2476); coronary artery disease (Disease Ontology:DOID:3393); carotid artery disease (Disease Ontology:DOID:3407); pulmonary fibrosis (Disease Ontology:DOID:3770); hyperglycemia (Disease Ontology:DOID:4195); myocardial infarction (Disease Ontology:DOID:5844); systemic juvenile rheumatoid arthritis (Disease Ontology:DOID:676); rheumatoid arthritis (Disease Ontology:DOID:7148); systemic lupus erythematosus (Disease Ontology:DOID:9074); aphthous stomatitis (Disease Ontology:DOID:9663)", "pathway": " (dme:Dmel_CG2830)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "10731132;12537569;12537572", "class_list": "", "function": "Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions., [UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 23, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "Q53YH7;Q961V0", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0051087 protein-folding chaperone binding;GO:0016887 ATP hydrolysis activity;GO:0140662 ATP-dependent protein folding chaperone", "go_cellular_component": "GO:0005743 mitochondrial inner membrane;GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0045041 protein import into mitochondrial intermembrane space;GO:0006457 protein folding;GO:0008637 apoptotic mitochondrial changes;GO:0042026 protein refolding;GO:0034514 mitochondrial unfolded protein response", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9VPS5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VPT8-1", "uniprot_id": "CPSF4_DROME", "mass": 33500.0, "length": 296, "protein_name": "Cleavage and polyadenylation specificity factor subunit 4", "gene_name": "Clp", "organism": "Fruit fly", "refseq_name": "clipper", "refseq_ac": "NP_477156", "gene_names_uniprotkb": "Clp; CG3642; CPSF30; Ssb-c6a", "gene_names_refseq": "CG3642; CLP; CPSF30; Clp; Cpsf30; Dmel\\CG3642; Ssb-c6a; c6a; clp", "protein_names_uniprotkb": "Cleavage and polyadenylation specificity factor subunit 4; 3.1.-.-; Cleavage and polyadenylation specificity factor 30 kDa subunit; Protein clipper", "protein_names_refseq": "CG3642-PA; Clp-PA; clipper; single stranded-binding protein c6a", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG3642); (R-DME-159231); (R-DME-73856); (R-DME-77595); (R-DME-9770562)", "pathway_count": 5, "publication_count": 6, "publication_id_list": "10731132;12537572;19450530;8206370;8943320;9512528", "class_list": "", "function": "Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. Has endonuclease activity. Binds RNA polymers with a preference for G- and/or C-rich clusters. Binds single-stranded DNA non-specifically., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0JQ42;Q24081", "ec_number_list": "2.3.2.-;2.7.7.19;2.7.7.6;3.1.3.16;3.6.4.13;3.4.21.-;3.1.27.-;3.1.-.-", "go_molecular_function": "GO:0003723 RNA binding;GO:0008270 zinc ion binding;GO:0016787 hydrolase activity;GO:0004521 RNA endonuclease activity", "go_cellular_component": "GO:0005847 mRNA cleavage and polyadenylation specificity factor complex", "go_biological_process": "GO:0006397 mRNA processing", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q9VPT8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VPW1-1", "uniprot_id": "ASTE_DROME", "mass": 98376.0, "length": 854, "protein_name": "Protein asteroid", "gene_name": "ast", "organism": "Fruit fly", "refseq_name": "asteroid", "refseq_ac": "NP_523451", "gene_names_uniprotkb": "ast; CG4426", "gene_names_refseq": "Ast; CG4426; Dmel\\CG4426; S[r]; Star/asteroid; ast", "protein_names_uniprotkb": "Protein asteroid", "protein_names_refseq": "CG4426-PA; Star-recessive; ast-PA; asteroid", "tax_id": 7227, "disease": "mismatch repair cancer syndrome (Disease Ontology:DOID:0112182); Lynch syndrome (Disease Ontology:DOID:3883)", "pathway": " (dme:Dmel_CG4426)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "10731132;12537569;12537572;9644838", "class_list": "", "function": "May function in EGF receptor signaling. May play a role in compound eye morphogenesis., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "B5RJ71;O61517;Q960G8", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "GO:0001745 compound eye morphogenesis;GO:0001752 compound eye photoreceptor fate commitment;GO:0007476 imaginal disc-derived wing morphogenesis;GO:0007526 larval somatic muscle development;GO:0008586 imaginal disc-derived wing vein morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q9VPW1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VQD2-1", "uniprot_id": "CP391_DROME", "mass": 57362.0, "length": 506, "protein_name": "Probable cytochrome P450 309a1", "gene_name": "Cyp309a1", "organism": "Fruit fly", "refseq_name": "cytochrome P450 309a1, isoform C", "refseq_ac": "NP_001259943", "gene_names_uniprotkb": "Cyp309a1; CG9964", "gene_names_refseq": "309a1; CG9964; CYP309A1; Cyp309A1; Cyp309a1; Dmel\\CG9964", "protein_names_uniprotkb": "Probable cytochrome P450 309a1; 1.14.-.-; CYPCCCIXA1", "protein_names_refseq": "CG9964-PC; Cyp309a1-PC; cytochrome P450 309a1, isoform C; cytochrome P450", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG9964)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "10731132;12537569;12537572;17372656", "class_list": "", "function": "May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "M9PCC5", "ec_number_list": "", "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0004497 monooxygenase activity;GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q9VQD2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VQD6-1", "uniprot_id": "ELBA2_DROME", "mass": 43310.0, "length": 381, "protein_name": "Early boundary activity protein 2", "gene_name": "Elba2", "organism": "Fruit fly", "refseq_name": "early boundary activity 2", "refseq_ac": "NP_608691", "gene_names_uniprotkb": "Elba2; CG9883", "gene_names_refseq": "CG9883; Dmel\\CG9883; Elba2; Elba", "protein_names_uniprotkb": "Early boundary activity protein 2", "protein_names_refseq": "CG9883-PA; Elba2-PA; early boundary activity 2; early boundary factor", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG9883)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "10731132;12537569;12537572;23240086;25561495", "class_list": "", "function": "The heterotrimeric Elba complex is required for chromatin domain boundary function during early embryogenesis. It binds to a 8-bp sequence 5'-CCAATAAG-3' in the Fab-7 insulator or boundary element in the bithorax complex and contributes to its insulator or boundary activity (PubMed:23240086). Elba2 can act as a transcriptional repressor and binds the palindromic sequence 5'-CCAATTGG-3' to mediate transcriptional repression (PubMed:25561495)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003682 chromatin binding;GO:0003714 transcription corepressor activity;GO:0043565 sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005677 chromatin silencing complex;GO:0005704 polytene chromosome band", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045666 positive regulation of neuron differentiation;GO:0045892 negative regulation of DNA-templated transcription;GO:0006325 chromatin organization;GO:0045746 negative regulation of Notch signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q9VQD6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VQF7-1", "uniprot_id": "BACC_DROME", "mass": 15460.0, "length": 152, "protein_name": "Bacchus", "gene_name": "Bacc", "organism": "Fruit fly", "refseq_name": "bacchus, isoform C", "refseq_ac": "NP_001245850", "gene_names_uniprotkb": "Bacc; CG9894", "gene_names_refseq": "Bacc; CG9894; Dmel\\CG9894; anon-EST:Liang-2.54; bacc; clone 2.54", "protein_names_uniprotkb": "Bacchus", "protein_names_refseq": "Bacc-PC; CG9894-PC; bacchus, isoform C; baccus", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG9894)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "10731132;11900973;12537572;23142736", "class_list": "", "function": "Negatively regulates tyramine beta-hydroxylase tbh and thus the conversion of tyramine (TA) to octopamine (OA). In tyrosine decarboxylase 2 (Tdc2) neurons, acts in an amine-mediated signaling pathway to negatively regulate acute ethanol sensitivity probably via tbh-mediated depletion of TA., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm", "go_biological_process": "GO:0048149 behavioral response to ethanol", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q9VQF7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VQG4-1", "uniprot_id": "COLT_DROME", "mass": 32952.0, "length": 306, "protein_name": "Congested-like trachea protein", "gene_name": "colt", "organism": "Fruit fly", "refseq_name": "congested-like trachea, isoform A", "refseq_ac": "NP_477221", "gene_names_uniprotkb": "colt; CG3057", "gene_names_refseq": "CACT; CG3057; Colt; Dmel\\CG3057; colt", "protein_names_uniprotkb": "Congested-like trachea protein", "protein_names_refseq": "CG3057-PA; carnitine Acyl-Carnitine translocase; collapsed trachea; colt-PA; congested-like trachea, isoform A", "tax_id": 7227, "disease": "carnitine-acylcarnitine translocase deficiency (Disease Ontology:DOID:0111585); lipid metabolism disorder (Disease Ontology:DOID:3146)", "pathway": " (dme:Dmel_CG3057); (R-DME-200425)", "pathway_count": 2, "publication_count": 4, "publication_id_list": "10731132;12537569;12537572;9409834", "class_list": "", "function": "Putative mitochondrial carrier of unknown solute specificity. Required for gas-filling of the tracheal system at hatching time of the embryo and for normal epithelial morphogenesis of the wings., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A4V020;O01396", "ec_number_list": "", "go_molecular_function": "GO:0015227 O-acyl-L-carnitine transmembrane transporter activity", "go_cellular_component": "GO:0005740 mitochondrial envelope;GO:0005743 mitochondrial inner membrane;GO:0016020 membrane", "go_biological_process": "GO:0006839 mitochondrial transport;GO:0003382 epithelial cell morphogenesis;GO:1902603 carnitine transmembrane transport;GO:0035002 liquid clearance, open tracheal system", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q9VQG4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VQQ9-1", "uniprot_id": "EXOC2_DROME", "mass": 100729.0, "length": 894, "protein_name": "Exocyst complex component 2", "gene_name": "Sec5", "organism": "Fruit fly", "refseq_name": "secretory 5", "refseq_ac": "NP_608780", "gene_names_uniprotkb": "Sec5; CG8843", "gene_names_refseq": "CG8843; Dmel\\CG8843; SEC5; Sec-5; Sec5p; Sec5; dsec5; sec5", "protein_names_uniprotkb": "Exocyst complex component 2; Exocyst complex component Sec5", "protein_names_refseq": "CG8843-PA; Sec5 ortholog; Sec5-PA; sec5; secretory 5", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG8843); (R-DME-264876); (R-DME-5620916)", "pathway_count": 3, "publication_count": 3, "publication_id_list": "10731132;12537569;12537572", "class_list": "", "function": "Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0031267 small GTPase binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0005938 cell cortex;GO:0031594 neuromuscular junction;GO:0055037 recycling endosome", "go_biological_process": "GO:0016080 synaptic vesicle targeting;GO:0072697 protein localization to cell cortex;GO:0099641 anterograde axonal protein transport;GO:0045087 innate immune response;GO:0072659 protein localization to plasma membrane", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9VQQ9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VR09-1", "uniprot_id": "Q9VR09_DROME", "mass": 11841.0, "length": 106, "protein_name": "Heterochromatin protein 6", "gene_name": "HP6", "organism": "Fruit fly", "refseq_name": "heterochromatin protein 6", "refseq_ac": "NP_608842", "gene_names_uniprotkb": "HP6; CG15636; Dmel\\CG15636; Dmel_CG15636; UMBREA; UMB; Umbrea; umbrea", "gene_names_refseq": "CG15636; Dmel\\CG15636; HP6; UMBREA; UMB; Umbrea; umbrea", "protein_names_uniprotkb": "Heterochromatin protein 6", "protein_names_refseq": "CG15636-PA; HP6-PA; heterochromatin protein 6; umbrea", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG15636)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003682 chromatin binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005730 nucleolus;GO:0000775 chromosome, centromeric region;GO:0000785 chromatin;GO:0000792 heterochromatin", "go_biological_process": "GO:0016233 telomere capping;GO:0007143 female meiotic nuclear division;GO:0031507 heterochromatin formation;GO:0051276 chromosome organization", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VR09-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VR17-1", "uniprot_id": "ELBA1_DROME", "mass": 41583.0, "length": 363, "protein_name": "Early boundary activity protein 1", "gene_name": "Elba1", "organism": "Fruit fly", "refseq_name": "early boundary activity 1", "refseq_ac": "NP_523472", "gene_names_uniprotkb": "Elba1; Bsg25A; CG12205", "gene_names_refseq": "Bsg25A; CG12205; Dmel\\CG12205; Elba1; Elba; anon-EST:Liang-1.70; bsg25A; clone 1.70; elba1", "protein_names_uniprotkb": "Early boundary activity protein 1; Blastoderm-specific gene 25A", "protein_names_refseq": "CG12205-PA; Elba1-PA; blastoderm-specific gene 25A; early boundary activity 1; early boundary factor", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG12205)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "10731132;12537569;12537572;23240086;25561495", "class_list": "", "function": "The heterotrimeric Elba complex is required for chromatin domain boundary function during early embryogenesis. It binds to a 8-bp sequence 5'-CCAATAAG-3' in the Fab-7 insulator or boundary element in the bithorax complex and contributes to its insulator or boundary activity (PubMed:23240086). Elba1 may act as a transcriptional repressor and binds the palindromic sequence 5'-CCAATTGG-3' to mediate transcriptional repression (PubMed:25561495)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "O01400;Q8SXI9", "ec_number_list": "", "go_molecular_function": "GO:0043035 chromatin insulator sequence binding;GO:0003714 transcription corepressor activity;GO:0043565 sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005677 chromatin silencing complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045666 positive regulation of neuron differentiation;GO:0045746 negative regulation of Notch signaling pathway;GO:0001700 embryonic development via the syncytial blastoderm;GO:0033696 heterochromatin boundary formation", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q9VR17-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VR82-1", "uniprot_id": "INX6_DROME", "mass": 55661.0, "length": 481, "protein_name": "Innexin inx6", "gene_name": "Inx6", "organism": "Fruit fly", "refseq_name": "innexin 6", "refseq_ac": "NP_572374", "gene_names_uniprotkb": "Inx6; CG17063; prp6", "gene_names_refseq": "CG17063; Dm-inx6; Dmel\\CG17063; FBpp0077031; Inx6; inx-6; inx6; prp6", "protein_names_uniprotkb": "Innexin inx6; Gap junction protein prp6; Innexin-6; Pas-related protein 6", "protein_names_refseq": "CG17063-PA; Inx6-PA; innexin 6; inx6; pas related protein 6", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG17063)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "10352230;10731132;11960713;12537572", "class_list": "", "function": "Structural components of the gap junctions., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9UA15", "ec_number_list": "", "go_molecular_function": "GO:0005243 gap junction channel activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane;GO:0005921 gap junction", "go_biological_process": "GO:0034220 monoatomic ion transmembrane transport;GO:0007602 phototransduction;GO:0010496 intercellular transport;GO:0072375 medium-term memory", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q9VR82-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VR91-1", "uniprot_id": "HERC2_DROME", "mass": 529997.0, "length": 4912, "protein_name": "Probable E3 ubiquitin-protein ligase HERC2", "gene_name": "HERC2", "organism": "Fruit fly", "refseq_name": "HECT and RLD domain containing protein 2", "refseq_ac": "NP_608388", "gene_names_uniprotkb": "HERC2; CG11734", "gene_names_refseq": "AF189221.1; CG11734; Dmel\\CG11734; HERC2; dHERC2", "protein_names_uniprotkb": "Probable E3 ubiquitin-protein ligase HERC2; 2.3.2.26; HECT domain and RCC1-like domain-containing protein 2; HECT-type E3 ubiquitin transferase HERC2", "protein_names_refseq": "CG11734-PC; HECT and RLD domain containing protein 2 ortholog; HECT and RLD domain containing protein 2; HERC2-PC", "tax_id": 7227, "disease": "autosomal recessive intellectual developmental disorder 38 (Disease Ontology:DOID:0081203); pigmentation disease (Disease Ontology:DOID:10123)", "pathway": " (dme:Dmel_CG11734); (R-DME-983168)", "pathway_count": 2, "publication_count": 5, "publication_id_list": "10720573;10731132;12537569;12537572;18327897", "class_list": "", "function": "Probable E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q8MZ96;Q9N2R1", "ec_number_list": "2.3.2.27;2.3.2.25;2.3.2.23;2.3.2.31;2.3.2.26;2.3.2.-;2.3.2.34;2.3.2.24", "go_molecular_function": "GO:0046872 metal ion binding;GO:0061630 ubiquitin protein ligase activity;GO:0004842 ubiquitin-protein transferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0016020 membrane;GO:0005814 centriole", "go_biological_process": "GO:0016567 protein ubiquitination;GO:0009966 regulation of signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q9VR91-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VRB3-1", "uniprot_id": "CP6V1_DROME", "mass": 60763.0, "length": 520, "protein_name": "Probable cytochrome P450 6v1", "gene_name": "Cyp6v1", "organism": "Fruit fly", "refseq_name": "cytochrome P450 6v1, isoform B", "refseq_ac": "NP_001285499", "gene_names_uniprotkb": "Cyp6v1; 6v1; CG1829; Dmel\\CG1829; Dmel_CG1829", "gene_names_refseq": "6v1; CG1829; Cyp6v1; Dmel\\CG1829", "protein_names_uniprotkb": "Probable cytochrome P450 6v1; 1.14.-.-; CYPVIV1", "protein_names_refseq": "CG1829-PB; Cyp6v1-PB; cytochrome P450 6v1, isoform B; cytochrome P450", "tax_id": 7227, "disease": "alcohol-associated liver disease (Disease Ontology:DOID:0070658); B-lymphoblastic leukemia/lymphoma (Disease Ontology:DOID:0080630); prostate cancer (Disease Ontology:DOID:10283); Alzheimer's disease (Disease Ontology:DOID:10652); essential hypertension (Disease Ontology:DOID:10825); familial Mediterranean fever (Disease Ontology:DOID:2987); oral submucous fibrosis (Disease Ontology:DOID:5773); chronic myeloid leukemia (Disease Ontology:DOID:8552); acute lymphoblastic leukemia (Disease Ontology:DOID:9952)", "pathway": " (dme:Dmel_CG1829)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 9, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A9UNF2", "ec_number_list": "", "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0004497 monooxygenase activity;GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0046680 response to DDT;GO:0046701 insecticide catabolic process", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VRB3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VRG7-1", "uniprot_id": "CNEP1_DROME", "mass": 28486.0, "length": 243, "protein_name": "CTD nuclear envelope phosphatase 1 homolog", "gene_name": "Ctdnep1; Dd", "organism": "Fruit fly", "refseq_name": "dullard, isoform A", "refseq_ac": "NP_608449", "gene_names_uniprotkb": "Ctdnep1; Dd; 20151539; BcDNA:LD08201; CG1696; DD; Dd; Dmel\\CG1696; Dmel_CG1696; anon-WO03040301.167; ddd; l(1)G0269", "gene_names_refseq": "20151539; BcDNA:LD08201; CG1696; Ctdnep1; DD; Dd; Dmel\\CG1696; anon-WO03040301.167; ddd; l(1)G0269", "protein_names_uniprotkb": "CTD nuclear envelope phosphatase 1 homolog; 3.1.3.16; Serine/threonine-protein phosphatase dullard homolog", "protein_names_refseq": "CG1696-PA; Dd-PA; d-dullard; dullard, isoform A; lethal (1) G0269", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG1696); (R-DME-4419969)", "pathway_count": 2, "publication_count": 12, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane., [UniProtKB, UniProtKB]; Serine/threonine protein phosphatase that may dephosphorylate and activate lipin-like phosphatases. Lipins are phosphatidate phosphatases that catalyze the conversion of phosphatidic acid to diacylglycerol and control the metabolism of fatty acids at different levels. May indirectly modulate the lipid composition of nuclear and/or endoplasmic reticulum membranes and be required for proper nuclear membrane morphology and/or dynamics. May also indirectly regulate the production of lipid droplets and triacylglycerol (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q8MT79", "ec_number_list": "3.1.3.16;3.1.3.48;3.1.3.27;3.1.3.-", "go_molecular_function": "GO:0004722 protein serine/threonine phosphatase activity;GO:0004721 phosphoprotein phosphatase activity;GO:0019211 phosphatase activator activity;GO:0016787 hydrolase activity", "go_cellular_component": "GO:0005635 nuclear envelope;GO:0005737 cytoplasm;GO:0031965 nuclear membrane;GO:0005789 endoplasmic reticulum membrane;GO:0008287 protein serine/threonine phosphatase complex", "go_biological_process": "GO:0030514 negative regulation of BMP signaling pathway;GO:0006998 nuclear envelope organization;GO:0010867 positive regulation of triglyceride biosynthetic process;GO:0007474 imaginal disc-derived wing vein specification;GO:0101025 nuclear membrane biogenesis", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "Q9VRG7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VRJ0-1", "uniprot_id": "GEN_DROME", "mass": 82534.0, "length": 726, "protein_name": "Flap endonuclease GEN", "gene_name": "Gen", "organism": "Fruit fly", "refseq_name": "XPG-like endonuclease", "refseq_ac": "NP_647943", "gene_names_uniprotkb": "Gen; CG10670", "gene_names_refseq": "BcDNA:GM10765; CG10670; DmGEN; DmGen; Dmel\\CG10670; GEN; Gen; mus324", "protein_names_uniprotkb": "Flap endonuclease GEN; 3.1.-.-; DmGEN; Flap structure-specific endonuclease GEN; Xpg-like endonuclease", "protein_names_refseq": "CG10670-PA; Gen-PA; XPG-like endonuclease; mutagen-sensitive 324", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG10670)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "10731132;12537569;12537572;15576351;17614965;18327897", "class_list": "", "function": "Endonuclease which cleaves flap structures at the junction between single-stranded DNA and double-stranded DNA. Specific for 5'-overhanging flap structures in which the 5'-upstream of the flap is completely double-stranded. Prefers the blocked-flap structures similar to those occurring at replication forks, in which the 5' single-strand overhang of the flap is double-stranded. Also possesses weak 5'- to 3'-exonuclease activity on nicked but not gapped double-stranded DNA. Does not cleave bubble-like or Holliday junction substrates., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9U9Q6", "ec_number_list": "", "go_molecular_function": "GO:0008310 single-stranded DNA 3'-5' DNA exonuclease activity;GO:0046872 metal ion binding;GO:0004520 DNA endonuclease activity;GO:0008311 double-stranded DNA 3'-5' DNA exonuclease activity;GO:0000400 four-way junction DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006281 DNA repair;GO:0006302 double-strand break repair", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q9VRJ0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VRJ8-1", "uniprot_id": "ASTER_DROME", "mass": 12082.0, "length": 108, "protein_name": "Protein Asterix", "gene_name": "CG10674", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": "NP_647950", "gene_names_uniprotkb": "CG10674", "gene_names_refseq": "CG10674; Dmel\\CG10674", "protein_names_uniprotkb": "Protein Asterix", "protein_names_refseq": "CG10674-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG10674)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "10731132;12537572", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q4QPW7", "ec_number_list": "", "go_molecular_function": "GO:0044183 protein folding chaperone", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0045048 protein insertion into ER membrane", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q9VRJ8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VRM7-1", "uniprot_id": "CP307_DROME", "mass": 62448.0, "length": 543, "protein_name": "Cytochrome P450 307a1", "gene_name": "spo", "organism": "Fruit fly", "refseq_name": "spook, isoform C", "refseq_ac": "NP_001286943", "gene_names_uniprotkb": "spo; CG10594; Cyp307a1", "gene_names_refseq": "307a1; CG10594; CYP307A1-Dm; CYP307A1; Cyp307a1; Dmel\\CG10594; Dmspo; Spo; spo", "protein_names_uniprotkb": "Cytochrome P450 307a1; 1.14.-.-; CYPCCCVIIA1; Protein spook", "protein_names_refseq": "CG10594-PC; spo-PC; spook, isoform C; spook", "tax_id": 7227, "disease": "Keshan disease (Disease Ontology:DOID:0050083); congenital adrenal hyperplasia (Disease Ontology:DOID:0050811); oral squamous cell carcinoma (Disease Ontology:DOID:0050866); Peters anomaly (Disease Ontology:DOID:0060673); anterior segment dysgenesis 6 (Disease Ontology:DOID:0080611); cholelithiasis (Disease Ontology:DOID:10211); prostate cancer (Disease Ontology:DOID:10283); stomach cancer (Disease Ontology:DOID:10534); primary open angle glaucoma (Disease Ontology:DOID:1070); hypertension (Disease Ontology:DOID:10763); hypospadias (Disease Ontology:DOID:10892); urinary bladder cancer (Disease Ontology:DOID:11054); buphthalmos (Disease Ontology:DOID:11211); hydrophthalmos (Disease Ontology:DOID:11212); heart disease (Disease Ontology:DOID:114); osteoporosis (Disease Ontology:DOID:11476); polycystic ovary syndrome (Disease Ontology:DOID:11612); clubfoot (Disease Ontology:DOID:11836); head and neck cancer (Disease Ontology:DOID:11934); hypertrophic cardiomyopathy (Disease Ontology:DOID:11984); Graves' disease (Disease Ontology:DOID:12361); Sjogren's syndrome (Disease Ontology:DOID:12894); dilated cardiomyopathy (Disease Ontology:DOID:12930); lung cancer (Disease Ontology:DOID:1324); Behcet's disease (Disease Ontology:DOID:13241); endometrial cancer (Disease Ontology:DOID:1380); Parkinson's disease (Disease Ontology:DOID:14330); cystic fibrosis (Disease Ontology:DOID:1485); breast cancer (Disease Ontology:DOID:1612); pancreatic cancer (Disease Ontology:DOID:1793); endometriosis (Disease Ontology:DOID:289); chronic obstructive pulmonary disease (Disease Ontology:DOID:3083); gallbladder cancer (Disease Ontology:DOID:3121); porphyria cutanea tarda (Disease Ontology:DOID:3132); breast adenocarcinoma (Disease Ontology:DOID:3458); esophagus squamous cell carcinoma (Disease Ontology:DOID:3748); lung squamous cell carcinoma (Disease Ontology:DOID:3907); renal cell carcinoma (Disease Ontology:DOID:4450); biliary tract cancer (Disease Ontology:DOID:4607); esophageal cancer (Disease Ontology:DOID:5041); pneumonia (Disease Ontology:DOID:552); myocardial infarction (Disease Ontology:DOID:5844); bronchitis (Disease Ontology:DOID:6132); reactive arthritis (Disease Ontology:DOID:6196); pulmonary hypertension (Disease Ontology:DOID:6432); ankylosing spondylitis (Disease Ontology:DOID:7147); end stage renal disease (Disease Ontology:DOID:783); periodontitis (Disease Ontology:DOID:824); chronic myeloid leukemia (Disease Ontology:DOID:8552); oral cavity cancer (Disease Ontology:DOID:8618); psoriasis (Disease Ontology:DOID:8893); psoriatic arthritis (Disease Ontology:DOID:9008); systemic lupus erythematosus (Disease Ontology:DOID:9074); acute myeloid leukemia (Disease Ontology:DOID:9119); diabetes mellitus (Disease Ontology:DOID:9351); type 2 diabetes mellitus (Disease Ontology:DOID:9352); multiple myeloma (Disease Ontology:DOID:9538); acute lymphoblastic leukemia (Disease Ontology:DOID:9952)", "pathway": " (dme:Dmel_CG10594)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "10328928;10731132;12537569;12537572;18327897", "class_list": "", "function": "Required for correct development of the embryonic midline glial cells which are necessary for the formation of distinct segmental commissures., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 58, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q8SZ84", "ec_number_list": "", "go_molecular_function": "GO:0005506 iron ion binding;GO:0016491 oxidoreductase activity;GO:0020037 heme binding;GO:0004497 monooxygenase activity;GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0042335 cuticle development;GO:0007417 central nervous system development;GO:0048566 embryonic digestive tract development;GO:0007494 midgut development;GO:0048477 oogenesis", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q9VRM7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VRP9-1", "uniprot_id": "BRE1_DROME", "mass": 119060.0, "length": 1044, "protein_name": "E3 ubiquitin-protein ligase Bre1", "gene_name": "Bre1", "organism": "Fruit fly", "refseq_name": "Bre1, isoform B", "refseq_ac": "NP_001286950", "gene_names_uniprotkb": "Bre1; BRE1; Bre-1; CG10542; Dmel\\CG10542; Dmel_CG10542; EC3-8; bre-1; bre1; dBRE1; dBre1; l(3)01640", "gene_names_refseq": "BRE1; Bre-1; Bre1; CG10542; Dmel\\CG10542; EC3-8; bre-1; bre1; dBRE1; dBre1; l(3)01640", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase Bre1; 2.3.2.27; RING-type E3 ubiquitin transferase Bre1; dBre1", "protein_names_refseq": "Bre1, isoform B; Bre1-PB; CG10542-PB; lethal (3) 01640", "tax_id": 7227, "disease": "nephrogenic diabetes insipidus (Disease Ontology:DOID:12387); breast cancer (Disease Ontology:DOID:1612); congenital heart disease (Disease Ontology:DOID:1682)", "pathway": " (dme:Dmel_CG10542); (R-DME-8866654); (R-DME-9013422)", "pathway_count": 3, "publication_count": 14, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;15691768;16110336;17569856;17569867;18327897;25589440;26109356;26109357", "class_list": "", "function": "E3 ubiquitin-protein ligase that mediates monoubiquitination of 'Lys-117' of histone H2B. H2B 'Lys-117' ubiquitination gives a specific tag for epigenetic transcriptional activation and is also prerequisite for histone H3 'Lys-4' and 'Lys-79' methylation. It thereby plays a central role in histone code and gene regulation. Required for the expression of Notch target genes in development by affecting the levels of Su(H) in imaginal disk cells and stimulating the Su(H)-mediated transcription of Notch-specific genes., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "C3KGI2;Q8IGT1;Q95TN7", "ec_number_list": "2.3.2.23;2.7.11.1;3.1.4.-;3.1.4.35;3.1.4.53;2.3.2.27", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0000785 chromatin;GO:0033503 HULC complex", "go_biological_process": "GO:0007219 Notch signaling pathway;GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0045597 positive regulation of cell differentiation;GO:0045893 positive regulation of DNA-templated transcription;GO:0006325 chromatin organization", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "Q9VRP9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VRQ7-1", "uniprot_id": "DPOE2_DROME", "mass": 58759.0, "length": 525, "protein_name": "DNA polymerase epsilon subunit 2", "gene_name": "PolE2", "organism": "Fruit fly", "refseq_name": "DNA polymerase epsilon subunit 2", "refseq_ac": "NP_647995", "gene_names_uniprotkb": "PolE2; CG10489; DNApol-epsilon58; DNApolE2", "gene_names_refseq": "10489; CG10489; DNApol-epsilon58; DNApol-epsilon; Dmel\\CG10489; POLE2; PolE2; Pole2; dpolepsilonp58; pol.epsilon 2", "protein_names_uniprotkb": "DNA polymerase epsilon subunit 2; DNA polymerase II subunit 2; DNA polymerase epsilon 58kD subunit; DNA polymerase epsilon subunit", "protein_names_refseq": "CG10489-PA; DNA polymerase epsilon 58kD subunit; DNA polymerase epsilon B subunit; DNA polymerase epsilon subunit 2; PolE2-PA; Pole2", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG10489); (R-DME-110314); (R-DME-5651801); (R-DME-5656169); (R-DME-5696400); (R-DME-6782135); (R-DME-68952); (R-DME-68962)", "pathway_count": 8, "publication_count": 5, "publication_id_list": "10731132;12537569;12537572;15135399;24224125", "class_list": "", "function": "Accessory component of the DNA polymerase epsilon complex (By similarity). Participates in DNA repair and in chromosomal DNA replication (By similarity). Has a role in the entrance and progression through S phase (PubMed:24224125). Has a role in endoreplication (PubMed:24224125). Essential for viability and tissue development (PubMed:24224125)., [UniProtKB, UniProtKB, PubMed, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A9UND8;D3DMG0;Q95RJ7", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding", "go_cellular_component": "GO:0008622 epsilon DNA polymerase complex", "go_biological_process": "GO:0032877 positive regulation of DNA endoreduplication;GO:0045004 DNA replication proofreading;GO:0042276 error-prone translesion synthesis;GO:0042023 DNA endoreduplication;GO:0006261 DNA-templated DNA replication", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q9VRQ7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VRY7-1", "uniprot_id": "Q9VRY7_DROME", "mass": 74025.0, "length": 659, "protein_name": "Radial spoke head protein 3, isoform B", "gene_name": "Rsph3", "organism": "Fruit fly", "refseq_name": "radial spoke head protein 3, isoform B", "refseq_ac": "NP_648059", "gene_names_uniprotkb": "Rsph3; CG10099; CG14912; CG32392; Dmel\\CG32392; Dmel_CG32392; dRSPH3; rsp3", "gene_names_refseq": "CG10099; CG14912; CG32392; Dmel\\CG32392; Rsph3; dRSPH3; rsp3", "protein_names_uniprotkb": "Radial spoke head protein 3, isoform B", "protein_names_refseq": "CG32392-PB; Rsph3-PB; radial spoke head protein 3, isoform B", "tax_id": 7227, "disease": "primary ciliary dyskinesia 32 (Disease Ontology:DOID:0110603)", "pathway": " (dme:Dmel_CG32392)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0005929 cilium;GO:0036126 sperm flagellum", "go_biological_process": "GO:0035082 axoneme assembly;GO:0007291 sperm individualization", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VRY7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VS05-1", "uniprot_id": "FOXF_DROME", "mass": 71063.0, "length": 676, "protein_name": "Forkhead box protein biniou", "gene_name": "bin", "organism": "Fruit fly", "refseq_name": "biniou", "refseq_ac": "NP_523950", "gene_names_uniprotkb": "bin; CG18647; FoxF", "gene_names_refseq": "BIN; Bin; CG18647; DmFoxF; Dmbin; Dmel\\CG18647; FOXF; FoxF; XIV; binI; bin; l(3)65CEe", "protein_names_uniprotkb": "Forkhead box protein biniou; DmFoxF; Forkhead box protein FoxF", "protein_names_refseq": "CG18647-PA; bin-PA; biniou; distal W5.4 group XIV", "tax_id": 7227, "disease": "persistent fetal circulation syndrome (Disease Ontology:DOID:13042)", "pathway": " (dme:Dmel_CG18647)", "pathway_count": 1, "publication_count": 14, "publication_id_list": "10731132;11691840;11804790;12175492;12537572;14523446;14718563;15750188;16171793;16987868;17511863;17908931;20736287;22378636", "class_list": "", "function": "Component of a regulatory network controlling visceral mesoderm development and midgut morphogenesis. Transcriptional regulator involved in the activation of a large number of genes in the visceral mesoderm including betaTub60D, dpp and Hand. Binds to and regulates a number of enhancers driving expression in the visceral mesoderm in a temporally and spatially restricted manner. Also to binds to enhancers cooperatively with activators, such as bap or HLH54F, to coregulate expression of shared target genes in the visceral mesoderm. Binds to the Ndg enhancer and drives expression of Ndg in the late visceral musculature. May be involved in the transcriptional regulation of wupA in the visceral mesoderm. Plays an indirect role in the later stages of salivary gland positioning., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q8T9N0;Q95WV0", "ec_number_list": "", "go_molecular_function": "GO:0000976 transcription cis-regulatory region binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0043565 sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0001710 mesodermal cell fate commitment;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0009887 animal organ morphogenesis", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "Q9VS05-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VS50-1", "uniprot_id": "ECO_DROME", "mass": 117414.0, "length": 1052, "protein_name": "N-acetyltransferase eco", "gene_name": "eco", "organism": "Fruit fly", "refseq_name": "establishment of cohesion, isoform A", "refseq_ac": "NP_648106", "gene_names_uniprotkb": "eco; CG8598", "gene_names_refseq": "CG8598; Deco; Dmel\\CG8598; ECO; Eco1; Eco; deco; eco", "protein_names_uniprotkb": "N-acetyltransferase eco; 2.3.1.-; ECO1 homolog; Establishment of cohesion 1 homolog", "protein_names_refseq": "CG8598-PA; drosophila eco1; eco-PA; establishment of cohesion, isoform A", "tax_id": 7227, "disease": "lung cancer (Disease Ontology:DOID:1324); lung adenocarcinoma (Disease Ontology:DOID:3910); Roberts syndrome (Disease Ontology:DOID:5325); rheumatoid arthritis (Disease Ontology:DOID:7148)", "pathway": " (dme:Dmel_CG8598); (R-DME-2468052)", "pathway_count": 2, "publication_count": 5, "publication_id_list": "10731132;12537569;12537572;14653991;18327897", "class_list": "", "function": "Acetyltransferase required for the establishment of sister chromatid cohesion and couple the processes of cohesion and DNA replication to ensure that only sister chromatids become paired together. In contrast to the structural cohesins, the deposition and establishment factors are required only during S phase., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A4V1K9;Q6AWN5;Q95RU6", "ec_number_list": "2.3.1.-", "go_molecular_function": "GO:0061733 protein-lysine-acetyltransferase activity;GO:0008270 zinc ion binding;GO:0016407 acetyltransferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0000785 chromatin", "go_biological_process": "GO:0007064 mitotic sister chromatid cohesion", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q9VS50-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VSA3-1", "uniprot_id": "ACADM_DROME", "mass": 45871.0, "length": 419, "protein_name": "Medium-chain specific acyl-CoA dehydrogenase, mitochondrial", "gene_name": "Mcad", "organism": "Fruit fly", "refseq_name": "Medium-chain acyl-CoA dehydrogenase", "refseq_ac": "NP_648149", "gene_names_uniprotkb": "Mcad; CG12262", "gene_names_refseq": "ACAD; CG 12262; CG12262; Dmel\\CG12262; MCAD; Mcad; mcad", "protein_names_uniprotkb": "Medium-chain specific acyl-CoA dehydrogenase, mitochondrial; 1.3.8.7", "protein_names_refseq": "CG12262-PA; Mcad-PA; Medium-chain acyl-CoA dehydrogenase; acyl-CoA dehdrogenase; medium chain acyl-CoA dehydrogenase; medium-chain acyl-coenzyme A dehydrogenase; probable medium-chain specific acyl-CoA dehydrogenase, mitochondrial", "tax_id": 7227, "disease": "medium chain acyl-CoA dehydrogenase deficiency (Disease Ontology:DOID:0080153); metabolic dysfunction-associated steatotic liver disease (Disease Ontology:DOID:0080208)", "pathway": " (dme:Dmel_CG12262); (R-DME-77288); (R-DME-77346); (R-DME-77348)", "pathway_count": 4, "publication_count": 4, "publication_id_list": "10731132;12537569;12537572;29563254", "class_list": "", "function": "Medium-chain specific acyl-CoA dehydrogenase that catalyzes the first step of mitochondrial fatty acid beta-oxidation, an aerobic process that breaks down fatty acids into acetyl-CoA and allows the production of energy from fats (PubMed:29563254). The first step of fatty acid beta-oxidation consists in the removal of one hydrogen from C-2 and C-3 of the straight-chain fatty acyl-CoA thioester, resulting in the formation of trans-2-enoyl-CoA (By similarity). Electron transfer flavoprotein (ETF) is the electron acceptor that transfers electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) (By similarity). May contribute to Pink1-mediated regulation of fatty acid and amino acid metabolism, through a mechanism that is independent of its acyl-CoA dehydrogenase activity (PubMed:29563254)., [UniProtKB, PubMed, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 3, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.3.8.7", "go_molecular_function": "GO:0003995 acyl-CoA dehydrogenase activity;GO:0050660 flavin adenine dinucleotide binding;GO:0070991 medium-chain fatty acyl-CoA dehydrogenase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix;GO:0005829 cytosol", "go_biological_process": "GO:0006635 fatty acid beta-oxidation;GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase;GO:0051793 medium-chain fatty acid catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q9VSA3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VSD7-1", "uniprot_id": "DBR1_DROME", "mass": 59462.0, "length": 534, "protein_name": "Lariat debranching enzyme", "gene_name": "ldbr", "organism": "Fruit fly", "refseq_name": "lariat debranching enzyme", "refseq_ac": "NP_996022", "gene_names_uniprotkb": "ldbr; CG7942; DBR1", "gene_names_refseq": "CG7942; Dmel\\CG7942; Lbdr; Ldbr; ldbr", "protein_names_uniprotkb": "Lariat debranching enzyme; 3.1.4.-; DmDBR1", "protein_names_refseq": "CG7942-PB; lariat debranching enzyme; lariat-debranching enzyme; ldbr-PB", "tax_id": 7227, "disease": "brain disease (Disease Ontology:DOID:936)", "pathway": " (dme:Dmel_CG7942)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "10731132;12537569;12537572", "class_list": "", "function": "Cleaves the 2'-5' phosphodiester linkage at the branch point of lariat intron pre-mRNAs after splicing and converts them into linear molecules that are subsequently degraded. It thereby facilitates ribonucleotide turnover., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A4V1M7", "ec_number_list": "", "go_molecular_function": "GO:0008419 RNA lariat debranching enzyme activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0000375 RNA splicing, via transesterification reactions;GO:0006396 RNA processing;GO:0000398 mRNA splicing, via spliceosome", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9VSD7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VSJ8-1", "uniprot_id": "EXOC7_DROME", "mass": 80026.0, "length": 693, "protein_name": "Exocyst complex component 7", "gene_name": "Exo70", "organism": "Fruit fly", "refseq_name": "exocyst 70", "refseq_ac": "NP_648222", "gene_names_uniprotkb": "Exo70; CG7127", "gene_names_refseq": "CG7127; Dmel\\CG7127; Exo70p; Exo70; exo70", "protein_names_uniprotkb": "Exocyst complex component 7; Exocyst complex component Exo70", "protein_names_refseq": "CG7127-PA; Exo70 ortholog; Exo70-PA; exocyst 70", "tax_id": 7227, "disease": "microcephaly (Disease Ontology:DOID:10907)", "pathway": " (dme:Dmel_CG7127); (R-DME-264876); (R-DME-5620916)", "pathway_count": 3, "publication_count": 5, "publication_id_list": "10731132;10908590;12537569;12537572;18327897", "class_list": "", "function": "Required for exocytosis. Thought to function in intracellular vesicle targeting and docking before SNARE complex formation., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q8T0E9", "ec_number_list": "", "go_molecular_function": "GO:0005546 phosphatidylinositol-4,5-bisphosphate binding;GO:0008013 beta-catenin binding", "go_cellular_component": "GO:0043195 terminal bouton;GO:0000145 exocyst", "go_biological_process": "GO:0016080 synaptic vesicle targeting;GO:0015031 protein transport;GO:0051124 synaptic assembly at neuromuscular junction;GO:0016192 vesicle-mediated transport;GO:0000281 mitotic cytokinesis", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q9VSJ8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VSS1-1", "uniprot_id": "ABCE1_DROME", "mass": 69298.0, "length": 611, "protein_name": "Protein Pixie", "gene_name": "pix", "organism": "Fruit fly", "refseq_name": "pixie, isoform A", "refseq_ac": "NP_648272", "gene_names_uniprotkb": "pix; ABCE1; CG5651", "gene_names_refseq": "ABCE1; BEST:GH18088; CG5651; DmCG5651; Dmel\\CG5651; E3-c; Pix; pix", "protein_names_uniprotkb": "Protein Pixie; ATP-binding cassette sub-family E member 1", "protein_names_refseq": "ABCE1; CG5651-PA; pix-PA; pixie, isoform A; pixie", "tax_id": 7227, "disease": "breast carcinoma (Disease Ontology:DOID:3459); lung adenocarcinoma (Disease Ontology:DOID:3910); human immunodeficiency virus infectious disease (Disease Ontology:DOID:526); hepatocellular carcinoma (Disease Ontology:DOID:684)", "pathway": " (dme:Dmel_CG5651); (R-DME-9954714)", "pathway_count": 2, "publication_count": 8, "publication_id_list": "10731132;12537569;12537572;16291791;17392269;18996366;25128630;29861391", "class_list": "", "function": "Plays a role in translation initiation and quality control of translation (PubMed:16291791, PubMed:17392269, PubMed:29861391). Together with pelo and HBS1, is required for 48S complex formation from 80S ribosomes and dissociation of vacant 80S ribosomes (PubMed:17392269). Stabilizes core components of eIF3 complex promoting their assembly into translation initiation-competent complexes (PubMed:17392269). Together with pelo and HBS1, recognizes stalled ribosomes and promotes dissociation of elongation complexes assembled on non-stop mRNAs; this triggers endonucleolytic cleavage of the mRNA, a mechanism to release non-functional ribosomes and to degrade damaged mRNAs as part of the No-Go Decay (NGD) pathway (PubMed:25128630). Plays a role in the regulation of mRNA turnover (By similarity). Plays a role in quality control of translation of mitochondrial outer membrane-localized mRNA (PubMed:29861391). As part of the Pink1-regulated signaling, ubiquitinated by Cnot4 upon mitochondria damage; this modification generates polyubiquitin signals that recruits autophagy receptors to the mitochondrial outer membrane to initiate mitophagy (PubMed:29861391). Required in the wing disk for cell division and growth as well as cell survival (PubMed:16291791). During muscle embryogenesis, required for the recruitment of Pak to muscle attachments in the embryo, hence may play a role in proper muscle morphogenesis and proper guidance and targeting of subsets of myotubes (PubMed:18996366)., [UniProtKB, PubMed, UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 5, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005506 iron ion binding;GO:0005524 ATP binding;GO:0051539 4 iron, 4 sulfur cluster binding;GO:0016887 ATP hydrolysis activity;GO:0043024 ribosomal small subunit binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0032790 ribosome disassembly;GO:0070481 nuclear-transcribed mRNA catabolic process, non-stop decay;GO:0006415 translational termination;GO:0006417 regulation of translation;GO:0043524 negative regulation of neuron apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q9VSS1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VSS7-1", "uniprot_id": "EVG1_DROME", "mass": 28564.0, "length": 250, "protein_name": "UPF0193 protein EVG1 homolog", "gene_name": "CG5280", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": "NP_648278", "gene_names_uniprotkb": "CG5280", "gene_names_refseq": "CG5280; Dmel\\CG5280", "protein_names_uniprotkb": "UPF0193 protein EVG1 homolog", "protein_names_refseq": "CG5280-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG5280)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "10731132;12537572", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q9VSS7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VT57-1", "uniprot_id": "CDK8_DROME", "mass": 53682.0, "length": 454, "protein_name": "Cyclin-dependent kinase 8", "gene_name": "Cdk8", "organism": "Fruit fly", "refseq_name": "Cyclin-dependent kinase 8", "refseq_ac": "NP_536735", "gene_names_uniprotkb": "Cdk8; CG10572", "gene_names_refseq": "CDK8; CG10572; Cdk8; DmCdk8; Dmel\\CG10572; cdk8; dCdk8; dTRAP56; p58", "protein_names_uniprotkb": "Cyclin-dependent kinase 8; 2.7.11.22; 2.7.11.23; Cell division protein kinase 8; DmCdk8; Mediator complex subunit Cdk8; Mediator of RNA polymerase II transcription subunit Cdk8", "protein_names_refseq": "CG10572-PA; Cdk8-PA; Cyclin-dependent kinase 8", "tax_id": 7227, "disease": "developmental and epileptic encephalopathy 87 (Disease Ontology:DOID:0112221); dilated cardiomyopathy (Disease Ontology:DOID:12930)", "pathway": " (dme:Dmel_CG10572); (R-DME-2173796); (R-DME-9841922)", "pathway_count": 3, "publication_count": 5, "publication_id_list": "10731132;12537569;12537572;17290221;8730095", "class_list": "", "function": "Component of the Mediator complex, a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional pre-initiation complex with RNA polymerase II and the general transcription factors. May phosphorylate the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAp II), which may inhibit the formation of a transcription initiation complex. Required for leg and eye development and macrochaete specification or differentiation., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "P91642;Q8MS41", "ec_number_list": "2.7.11.17;2.7.11.1;2.7.11.13;2.7.11.24;2.3.1.48;2.7.11.22;2.7.11.23;2.7.11.21;5.6.1.8;2.7.11.11;2.7.12.1;2.7.11.25;2.7.11.12;2.7.12.2;2.7.10.2;2.7.11.39", "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0004693 cyclin-dependent protein serine/threonine kinase activity;GO:0008353 RNA polymerase II CTD heptapeptide repeat kinase activity;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0016592 mediator complex;GO:1990508 CKM complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006468 protein phosphorylation;GO:0000082 G1/S transition of mitotic cell cycle;GO:0034472 snRNA 3'-end processing;GO:0045498 sex comb development", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q9VT57-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VTC4-1", "uniprot_id": "GALL2_DROME", "mass": 17587.0, "length": 156, "protein_name": "MIP18 family protein galla-2", "gene_name": "galla-2", "organism": "Fruit fly", "refseq_name": "galla-2", "refseq_ac": "NP_648416", "gene_names_uniprotkb": "galla-2; CG7949", "gene_names_refseq": "CG7949; CIAO2B; Dmel\\CG7949; Galla-2; Galla2; galla-2; galla2", "protein_names_uniprotkb": "MIP18 family protein galla-2", "protein_names_refseq": "CG7949-PA; galla-2-PA; galla-2", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG7949)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "10731132;12537572;25065591", "class_list": "", "function": "Component of the crb-galla-Xpd (CGX) complex which is essential for proper mitotic chromosome segregation in early embryos. The CGX complex is also required for cell proliferation in developing wing disks. In the CGX complex, acts with crb to recruit Xpd thus forming the functional complex., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0097361 cytosolic [4Fe-4S] assembly targeting complex;GO:0005829 cytosol", "go_biological_process": "GO:0007059 chromosome segregation;GO:0051301 cell division;GO:0051604 protein maturation;GO:0044572 [4Fe-4S] cluster assembly", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9VTC4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VTE0-1", "uniprot_id": "BL1S2_DROME", "mass": 17564.0, "length": 159, "protein_name": "Biogenesis of lysosome-related organelles complex 1 subunit 2", "gene_name": "Blos2", "organism": "Fruit fly", "refseq_name": "biogenesis of lysosome-related organelles complex 1, subunit 2", "refseq_ac": "NP_648427", "gene_names_uniprotkb": "Blos2; CG14145", "gene_names_refseq": "BLOS2; Blos2; CG14145; DmBlos2; Dmel\\CG14145; NP_648427; blos2", "protein_names_uniprotkb": "Biogenesis of lysosome-related organelles complex 1 subunit 2; BLOC-1 subunit 2", "protein_names_refseq": "BLOC-1 subunit 2; Blos2-PA; CG14145-PA; biogenesis of lysosome-related organelles complex 1, subunit 2", "tax_id": 7227, "disease": "Hermansky-Pudlak syndrome (Disease Ontology:DOID:3753)", "pathway": " (dme:Dmel_CG14145)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "10731132;12537569;12537572;20015953", "class_list": "", "function": "Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1) involved in pigment granule biogenesis., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0042803 protein homodimerization activity;GO:0043015 gamma-tubulin binding", "go_cellular_component": "GO:0098574 cytoplasmic side of lysosomal membrane;GO:0099078 BORC complex;GO:0031083 BLOC-1 complex;GO:0000930 gamma-tubulin complex", "go_biological_process": "GO:0008057 eye pigment granule organization;GO:0016197 endosomal transport;GO:0032418 lysosome localization;GO:0072384 organelle transport along microtubule;GO:0061909 autophagosome-lysosome fusion", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q9VTE0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VTJ4-1", "uniprot_id": "FUCO_DROME", "mass": 57723.0, "length": 494, "protein_name": "Putative alpha-L-fucosidase", "gene_name": "Fuca", "organism": "Fruit fly", "refseq_name": "alpha-L-fucosidase, isoform C", "refseq_ac": "NP_001303363", "gene_names_uniprotkb": "Fuca; CG6128", "gene_names_refseq": "CG33047; CG6128; DmFuca; Dmel\\CG6128; Fuca_Dm; Fuca; Fuc; a-FUC; alpha-FUC; fuc", "protein_names_uniprotkb": "Putative alpha-L-fucosidase; 3.2.1.51; Alpha-L-fucoside fucohydrolase", "protein_names_refseq": "CG6128-PC; Fuca-PC; alpha fucosidase; alpha-L-fucosidase, isoform C; alpha-fucosidase", "tax_id": 7227, "disease": "fucosidosis (Disease Ontology:DOID:14500); diabetic retinopathy (Disease Ontology:DOID:8947); diabetes mellitus (Disease Ontology:DOID:9351); type 2 diabetes mellitus (Disease Ontology:DOID:9352); type 1 diabetes mellitus (Disease Ontology:DOID:9744)", "pathway": " (dme:Dmel_CG6128); (R-DME-381426); (R-DME-6798695); (R-DME-8957275); (R-DME-975578)", "pathway_count": 5, "publication_count": 4, "publication_id_list": "10731132;11698403;12537569;12537572", "class_list": "", "function": "Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "A4V1U8", "ec_number_list": "1.-.-.-;1.14.18.1;1.10.3.1;3.5.2.17;3.2.1.17;3.2.1.31;2.7.11.1;3.1.1.3;3.5.3.1;2.7.11.24;5.3.4.1;2.7.11.13;1.1.1.205;3.6.4.6;1.16.3.1;3.2.1.-;3.4.19.9;3.5.1.26;5.3.99.3;2.7.10.2;3.2.1.23;3.4.24.81;1.10.3.3;3.4.21.112;6.3.4.21;4.6.1.19;3.2.1.51;2.4.1.145;3.1.1.98;3.5.4.4;1.11.2.-;2.4.1.1;1.6.2.2", "go_molecular_function": "GO:0042806 fucose binding;GO:0004560 alpha-L-fucosidase activity", "go_cellular_component": "GO:0005764 lysosome;GO:0097524 sperm plasma membrane;GO:0002081 outer acrosomal membrane", "go_biological_process": "GO:0007339 binding of sperm to zona pellucida;GO:0042742 defense response to bacterium;GO:0016139 glycoside catabolic process;GO:0006004 fucose metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q9VTJ4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VTM0-1", "uniprot_id": "BL1S6_DROME", "mass": 18963.0, "length": 167, "protein_name": "Biogenesis of lysosome-related organelles complex 1 subunit 6", "gene_name": "Pldn", "organism": "Fruit fly", "refseq_name": "pallidin", "refseq_ac": "NP_648494", "gene_names_uniprotkb": "Pldn; CG14133; Pallidin", "gene_names_refseq": "CG14133; Dmel\\CG14133; NP_648494; Pldn; pallidin; pldn", "protein_names_uniprotkb": "Biogenesis of lysosome-related organelles complex 1 subunit 6; BLOC-1 subunit 6; Pallid protein homolog", "protein_names_refseq": "CG14133-PB; Pldn-PB; pallidin ortholog; pallidin", "tax_id": 7227, "disease": "Hermansky-Pudlak syndrome 9 (Disease Ontology:DOID:0060547); platelet storage pool deficiency (Disease Ontology:DOID:2223); pulmonary emphysema (Disease Ontology:DOID:9675)", "pathway": " (dme:Dmel_CG14133)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "10731132;12537572;20015953;28317021", "class_list": "", "function": "Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1) involved in pigment granule biogenesis and membrane trafficking in synapses (PubMed:20015953, PubMed:28317021). In response to high synaptic activity at neuromuscular junctions, plays a key role in promoting efficient synaptic vesicle recycling and re-formation through early endosomes (PubMed:28317021)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005856 cytoskeleton;GO:0031594 neuromuscular junction;GO:0030133 transport vesicle;GO:0030018 Z disc;GO:0031083 BLOC-1 complex", "go_biological_process": "GO:0008057 eye pigment granule organization;GO:0036466 synaptic vesicle recycling via endosome;GO:0098693 regulation of synaptic vesicle cycle", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q9VTM0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VTT9-1", "uniprot_id": "DEFI8_DROME", "mass": 55408.0, "length": 492, "protein_name": "Differentially expressed in FDCP 8 homolog", "gene_name": "DEF8", "organism": "Fruit fly", "refseq_name": "differentially expressed in FDCP 8 homolog", "refseq_ac": "NP_648549", "gene_names_uniprotkb": "DEF8; CG11534", "gene_names_refseq": "BEST:GH12489; CG11534; DEF8; Def8; Dmel\\CG11534", "protein_names_uniprotkb": "Differentially expressed in FDCP 8 homolog", "protein_names_refseq": "CG11534-PA; DEF8-PA; differentially expressed in FDCP 8 homolog", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG11534)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "10731132;12537569;12537572", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9VTT9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VTU4-1", "uniprot_id": "EIF3L_DROME", "mass": 63223.0, "length": 539, "protein_name": "Eukaryotic translation initiation factor 3 subunit L", "gene_name": "eIF3l", "organism": "Fruit fly", "refseq_name": "eukaryotic translation initiation factor 3 subunit l", "refseq_ac": "NP_648553", "gene_names_uniprotkb": "eIF3l; CG5642", "gene_names_refseq": "CG5642; Dmel\\CG5642; eIF3l", "protein_names_uniprotkb": "Eukaryotic translation initiation factor 3 subunit L; eIF3l", "protein_names_refseq": "CG5642-PA; eIF3l-PA; eukaryotic translation initiation factor 3 subunit l", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG5642); (R-DME-156827); (R-DME-72649); (R-DME-72689); (R-DME-72695); (R-DME-72702)", "pathway_count": 6, "publication_count": 3, "publication_id_list": "10731132;12537569;12537572", "class_list": "", "function": "Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003743 translation initiation factor activity", "go_cellular_component": "GO:0005829 cytosol;GO:0016282 eukaryotic 43S preinitiation complex;GO:0033290 eukaryotic 48S preinitiation complex;GO:0005852 eukaryotic translation initiation factor 3 complex", "go_biological_process": "GO:0006413 translational initiation;GO:0001732 formation of cytoplasmic translation initiation complex", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9VTU4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VU31-1", "uniprot_id": "EXD1_DROME", "mass": 30279.0, "length": 265, "protein_name": "Protein Exd1 homolog", "gene_name": "CG11263", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform B", "refseq_ac": "NP_001163435", "gene_names_uniprotkb": "CG11263", "gene_names_refseq": "CG11263; Dmel\\CG11263", "protein_names_uniprotkb": "Protein Exd1 homolog; DmExd1; Exonuclease 3'-5' domain-containing protein 1 homolog; Exonuclease 3'-5' domain-like-containing protein 1 homolog", "protein_names_refseq": "CG11263-PB; uncharacterized protein, isoform B", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG11263)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "10731132;12537569;12537572;26669262", "class_list": "", "function": "RNA-binding protein. Inactive exonuclease., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding;GO:0042803 protein homodimerization activity", "go_cellular_component": "GO:1990923 PET complex;GO:0043186 P granule", "go_biological_process": "GO:0034587 piRNA processing", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q9VU31-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VU95-1", "uniprot_id": "AGT2L_DROME", "mass": 54284.0, "length": 494, "protein_name": "Alanine--glyoxylate aminotransferase 2-like", "gene_name": "CG8745", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": "NP_648665", "gene_names_uniprotkb": "CG8745", "gene_names_refseq": "CG8745; Dmel\\CG8745", "protein_names_uniprotkb": "Alanine--glyoxylate aminotransferase 2-like; 4.2.3.-", "protein_names_refseq": "CG8745-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG8745); (R-DME-1442490); (R-DME-1483213); (R-DME-71064)", "pathway_count": 4, "publication_count": 3, "publication_id_list": "10731132;12537569;12537572", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q95RV4", "ec_number_list": "4.2.3.-", "go_molecular_function": "GO:0030170 pyridoxal phosphate binding;GO:0050459 ethanolamine-phosphate phospho-lyase activity", "go_cellular_component": "", "go_biological_process": "GO:0035094 response to nicotine", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9VU95-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VUC6-1", "uniprot_id": "FRL_DROME", "mass": 133159.0, "length": 1183, "protein_name": "Formin-like protein", "gene_name": "Frl", "organism": "Fruit fly", "refseq_name": "Formin-like, isoform C", "refseq_ac": "NP_001137948", "gene_names_uniprotkb": "Frl; CG32138", "gene_names_refseq": "CG13485; CG32138; CG43986; CG6807; Dmel\\CG32138; Frl; Q9VUC5_DROME; Q9VUC6_DROME; anon-WO0172774.98; frl", "protein_names_uniprotkb": "Formin-like protein; Formin related in leukocytes", "protein_names_refseq": "CG32138-PC; Formin-like, isoform C; Frl-PC", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG32138); (R-DME-5663220); (R-DME-8980692); (R-DME-9013149)", "pathway_count": 4, "publication_count": 5, "publication_id_list": "10731132;12537572;17372656;26801180;40245499", "class_list": "", "function": "Together with Cdc42, involved in establishment of planar cell polarity in the developing compound eye by contributing to ommatidial rotation. Together with DAAM and Cdc42, has a role in neuronal development of mushroom bodies., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 1, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "B7Z050;M9PCF8;Q86NT2;Q9VUC5", "ec_number_list": "", "go_molecular_function": "GO:0051015 actin filament binding;GO:0051020 GTPase binding;GO:0031267 small GTPase binding", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0016477 cell migration;GO:0008360 regulation of cell shape;GO:0030866 cortical actin cytoskeleton organization;GO:0048675 axon extension;GO:0016318 ommatidial rotation", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q9VUC6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VUK8-1", "uniprot_id": "GARS_DROME", "mass": 85192.0, "length": 765, "protein_name": "Glycine--tRNA ligase", "gene_name": "GlyRS", "organism": "Fruit fly", "refseq_name": "Glycyl-tRNA synthetase, isoform C", "refseq_ac": "NP_001261867", "gene_names_uniprotkb": "GlyRS; Aat-gly; Aats-gly; CG6778; GRS; aaRS(Gly); gars; team", "gene_names_refseq": "Aat-gly; Aats-gly; CG6778; Dmel\\CG6778; GARS; GRS; Gars; GlyRS; aaRS(Gly); dGARS1; dGARS; dGars; gars; team", "protein_names_uniprotkb": "Glycine--tRNA ligase; 2.7.7.-; 6.1.1.14; Diadenosine tetraphosphate synthetase; Glycyl-tRNA synthetase", "protein_names_refseq": "CG6778-PC; GlyRS-PC; Glycyl-tRNA synthetase, isoform C; glycyl-tRNA synthetase; terminal arbors missing", "tax_id": 7227, "disease": "Charcot-Marie-Tooth disease type 2 (Disease Ontology:DOID:0050539); Charcot-Marie-Tooth disease type 2D (Disease Ontology:DOID:0110164); autosomal dominant distal hereditary motor neuronopathy 5 (Disease Ontology:DOID:0111203); Charcot-Marie-Tooth disease (Disease Ontology:DOID:10595); spinal muscular atrophy (Disease Ontology:DOID:12377)", "pathway": " (dme:Dmel_CG6778)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "10731132;12537569;12537572;17529987;24807208;25972375;29520219", "class_list": "", "function": "Catalyzes the ATP-dependent ligation of glycine to the 3'-end of its cognate tRNA, via the formation of an aminoacyl-adenylate intermediate (Gly-AMP). Also produces diadenosine tetraphosphate (Ap4A), a universal pleiotropic signaling molecule needed for cell regulation pathways, by direct condensation of 2 ATPs. Thereby, may play a special role in Ap4A homeostasis (By similarity). Required for terminal arborization of both dendrites and axons during development (PubMed:17529987)., [UniProtKB, UniProtKB, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 5, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "C9QP25;Q961R8", "ec_number_list": "2.7.7.-;6.1.1.14", "go_molecular_function": "GO:0005524 ATP binding;GO:0016740 transferase activity;GO:0004820 glycine-tRNA ligase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0030424 axon", "go_biological_process": "GO:0048813 dendrite morphogenesis;GO:0070150 mitochondrial glycyl-tRNA aminoacylation;GO:0006426 glycyl-tRNA aminoacylation", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q9VUK8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VUL9-1", "uniprot_id": "FUTA_DROME", "mass": 59160.0, "length": 503, "protein_name": "Core alpha-(1,3)-fucosyltransferase", "gene_name": "FucTA", "organism": "Fruit fly", "refseq_name": "alpha1,3-fucosyltransferase A, isoform B", "refseq_ac": "NP_001261872", "gene_names_uniprotkb": "FucTA; CG6869", "gene_names_refseq": "3-FucT; CG6869; Dm alpha1; Dmel\\CG6869; FucTA; anon-EST:Posey285; fucTA", "protein_names_uniprotkb": "Core alpha-(1,3)-fucosyltransferase; 2.4.1.214; Alpha(1,3)-fucosyltransferase A; Glycoprotein 3-alpha-L-fucosyltransferase FucTA", "protein_names_refseq": "CG6869-PB; FucTA-PB; alpha1,3-fucosyltransferase A, isoform B; alpha1,3-fucosyltransferase; core alpha1,3-fucosyltransferase; core fucosyltransferase", "tax_id": 7227, "disease": "candidiasis (Disease Ontology:DOID:1508)", "pathway": " (dme:Dmel_CG6869); (R-DME-9037629); (R-DME-975578)", "pathway_count": 3, "publication_count": 6, "publication_id_list": "10731132;11382750;12537569;12537572;16314421;21203496", "class_list": "", "function": "Core alpha1,3-fucosyltransferase that catalyzes the addition of fucose in an alpha 1-3 linkage to the innermost GlcNAc residue of N-glycans attached to the peptide (PubMed:11382750, PubMed:16314421). The presence of alpha 1,6-linked fucose enhances the activity (PubMed:11382750, PubMed:16314421). Plays a role in neuronal development by promoting ventral nerve cord formation, possibly by promoting interactions between migrating cells and the extracellular matrix or by promoting neural activity (PubMed:21203496)., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "I0DHK8;Q8SYT5", "ec_number_list": "2.4.1.214", "go_molecular_function": "GO:0046920 alpha-(1->3)-fucosyltransferase activity;GO:0018392 glycoprotein 3-alpha-L-fucosyltransferase activity", "go_cellular_component": "GO:0032580 Golgi cisterna membrane;GO:0005797 Golgi medial cisterna", "go_biological_process": "GO:0007399 nervous system development;GO:0006487 protein N-linked glycosylation;GO:0016258 Golgi apparatus N-glycan diversification", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q9VUL9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VUT6-1", "uniprot_id": "GALT8_DROME", "mass": 68100.0, "length": 590, "protein_name": "Polypeptide N-acetylgalactosaminyltransferase 8", "gene_name": "Pgant8", "organism": "Fruit fly", "refseq_name": "polypeptide N-Acetylgalactosaminyltransferase 8", "refseq_ac": "NP_648800", "gene_names_uniprotkb": "Pgant8; CG7297", "gene_names_refseq": "CG7297; Dmel\\CG7297; Pgant8; pgant8", "protein_names_uniprotkb": "Polypeptide N-acetylgalactosaminyltransferase 8; 2.4.1.41; Protein-UDP acetylgalactosaminyltransferase 8; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 8; pp-GaNTase 8", "protein_names_refseq": "CG7297-PA; Pgant8-PA; polypeptide GalNAc transferase 8; polypeptide N-Acetylgalactosaminyltransferase 8", "tax_id": 7227, "disease": "depressive disorder (Disease Ontology:DOID:1596)", "pathway": " (dme:Dmel_CG7297); (R-DME-913709)", "pathway_count": 2, "publication_count": 5, "publication_id_list": "10731132;12537569;12537572;12829714;16251381", "class_list": "", "function": "Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. It can both act as a peptide transferase that transfers GalNAc onto unmodified peptide substrates, and as a glycopeptide transferase that requires the prior addition of a GalNAc on a peptide before adding additional GalNAc moieties. Prefers both EA2 and the diglycosylated Muc5AC-3/13 as substrates, albeit at very low levels fro Muc5AC-3/13., [UniProtKB, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.4.1.-;2.4.1.41", "go_molecular_function": "GO:0046872 metal ion binding;GO:0030246 carbohydrate binding;GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005794 Golgi apparatus;GO:0005795 Golgi stack", "go_biological_process": "GO:0006493 protein O-linked glycosylation;GO:0016266 protein O-linked glycosylation via N-acetyl-galactosamine", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q9VUT6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VV87-1", "uniprot_id": "ELOV6_DROME", "mass": 36829.0, "length": 316, "protein_name": "Very long chain fatty acid elongase 6", "gene_name": "Baldspot", "organism": "Fruit fly", "refseq_name": "baldspot, isoform A", "refseq_ac": "NP_648909", "gene_names_uniprotkb": "Baldspot; CG3971; l(3)01895; l(3)02281; l(3)04106; l(3)neo21; l(3)neo22; noa", "gene_names_refseq": "Baldspot; CG 3971; CG3971; Dmel\\CG3971; ELOVL6; Elovl6; NEST:bs18f10; NEST:bs18g10; baldspot; blp; l(3)01895; l(3)02281; l(3)04106; l(3)neo21; l(3)neo22; noa", "protein_names_uniprotkb": "Very long chain fatty acid elongase 6; 2.3.1.199; ELOVL6; Elongation of very long chain fatty acids protein 6; Neighbor of abl; Very-long-chain 3-oxoacyl-CoA synthase", "protein_names_refseq": "Baldspot-PA; CG3971-PA; baldspot, isoform A; baldspot; neighbor of abl", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG3971); (R-DME-2046105); (R-DME-2046106); (R-DME-75876)", "pathway_count": 4, "publication_count": 5, "publication_id_list": "10731132;12537572;17666430;26214738;30081392", "class_list": "", "function": "Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle (PubMed:26214738). This process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle (PubMed:26214738). Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs (By similarity). Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degree (By similarity). May participate in the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators (By similarity)., [UniProtKB, UniProtKB, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "Q95T92;Q9NB55", "ec_number_list": "2.3.1.199", "go_molecular_function": "GO:0009922 fatty acid elongase activity", "go_cellular_component": "GO:0005741 mitochondrial outer membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0030148 sphingolipid biosynthetic process;GO:0030497 fatty acid elongation;GO:0034625 fatty acid elongation, monounsaturated fatty acid;GO:0034626 fatty acid elongation, polyunsaturated fatty acid;GO:0042759 long-chain fatty acid biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q9VV87-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VVB4-1", "uniprot_id": "CCD22_DROME", "mass": 63013.0, "length": 555, "protein_name": "Coiled-coil domain-containing protein 22 homolog", "gene_name": "CG9951", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": "NP_648929", "gene_names_uniprotkb": "CG9951", "gene_names_refseq": "CG9951; Dmel\\CG9951", "protein_names_uniprotkb": "Coiled-coil domain-containing protein 22 homolog", "protein_names_refseq": "CG9951-PA; uncharacterized protein", "tax_id": 7227, "disease": "Ritscher-Schinzel syndrome 2 (Disease Ontology:DOID:0060572)", "pathway": " (dme:Dmel_CG9951); (R-DME-8951664)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "10731132;12537569;12537572", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0097602 cullin family protein binding", "go_cellular_component": "", "go_biological_process": "GO:2000060 positive regulation of ubiquitin-dependent protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9VVB4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VVN4-1", "uniprot_id": "ATRIP_DROME", "mass": 96119.0, "length": 846, "protein_name": "ATR-interacting protein mus304", "gene_name": "mus304", "organism": "Fruit fly", "refseq_name": "mutagen-sensitive 304", "refseq_ac": "NP_524135", "gene_names_uniprotkb": "mus304; CG7347", "gene_names_refseq": "ATRIP; CG7347; Dmel\\CG7347; Mus304; anon-WO0140519.82; atrip; mus(3)304; mus-304; mus304", "protein_names_uniprotkb": "ATR-interacting protein mus304; Mutagen-sensitive protein 304", "protein_names_refseq": "ATR-interacting protein; CG7347-PA; mus304-PA; mutagen sensitive 304; mutagen-sensitive 304", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG7347); (R-DME-176187); (R-DME-69473)", "pathway_count": 3, "publication_count": 7, "publication_id_list": "10731132;10733527;12361566;12537569;12537572;14729967;18984573", "class_list": "", "function": "DNA damage checkpoint protein required for chromosome break repair and for genomic stability during development., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 3, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "B6UXA1;B6UXA5;B6UXA6;B6UXA7;B6UXA8;B6UXA9;B6UXB0;B6UXB1;B6UXB2;B6UXB3;B6UXB4;B6UXB5;B6UXB6;B6UXB7;B6UXB8;B6UXB9;B6UXC0;B6UXC1;B6UXC2;B6UXC3;B6UXC4;B6UXC5;B6UXC6;B6UXC7;B6UXC8;B6UXC9;B6UXD0;B6UXD1", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0016321 female meiosis chromosome segregation;GO:0006281 DNA repair;GO:0000723 telomere maintenance;GO:0007143 female meiotic nuclear division;GO:0006139 nucleobase-containing compound metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q9VVN4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VVR2-1", "uniprot_id": "BORA_DROME", "mass": 59142.0, "length": 539, "protein_name": "Protein aurora borealis", "gene_name": "bora", "organism": "Fruit fly", "refseq_name": "aurora borealis", "refseq_ac": "NP_649048", "gene_names_uniprotkb": "bora; CG6897", "gene_names_refseq": "CG6897; Dmel\\CG6897; bora", "protein_names_uniprotkb": "Protein aurora borealis", "protein_names_refseq": "CG6897-PA; aurora borealis; bora-PA; borealis", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG6897); (R-DME-2565942); (R-DME-69273)", "pathway_count": 3, "publication_count": 4, "publication_id_list": "10731132;12537572;16890155;18327897", "class_list": "", "function": "Required for the activation of Aurora-A (aur) at the onset of mitosis., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0019901 protein kinase binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0051301 cell division;GO:0032147 activation of protein kinase activity;GO:0060236 regulation of mitotic spindle organization;GO:0007088 regulation of mitotic nuclear division;GO:0045167 asymmetric protein localization involved in cell fate determination", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q9VVR2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VVR9-1", "uniprot_id": "C12C1_DROME", "mass": 60598.0, "length": 524, "protein_name": "Probable cytochrome P450 12c1, mitochondrial", "gene_name": "Cyp12c1", "organism": "Fruit fly", "refseq_name": "cytochrome P450 12c1, isoform B", "refseq_ac": "NP_001287109", "gene_names_uniprotkb": "Cyp12c1; 12c1; CG4120; Cyp12C1; Cyp12c; Dmel\\CG4120; Dmel_CG4120; cyp12c1", "gene_names_refseq": "12c1; CG4120; Cyp12C1; Cyp12c1; Cyp12c; Dmel\\CG4120; cyp12c1", "protein_names_uniprotkb": "Probable cytochrome P450 12c1, mitochondrial; 1.14.-.-; CYPXIIC1", "protein_names_refseq": "CG4120-PB; Cyp12c1-PB; cytochrome P450 12c1, isoform B", "tax_id": 7227, "disease": "colorectal adenoma (Disease Ontology:DOID:0050860); colorectal adenocarcinoma (Disease Ontology:DOID:0050861); oral squamous cell carcinoma (Disease Ontology:DOID:0050866); infantile hypercalcemia 1 (Disease Ontology:DOID:0061136); metabolic dysfunction-associated steatohepatitis (Disease Ontology:DOID:0080547); childhood-onset asthma (Disease Ontology:DOID:0080815); vitamin D-dependent rickets type 1A (Disease Ontology:DOID:0080886); pre-eclampsia (Disease Ontology:DOID:10591); rickets (Disease Ontology:DOID:10609); gestational diabetes (Disease Ontology:DOID:11714); lung cancer (Disease Ontology:DOID:1324); extrahepatic cholestasis (Disease Ontology:DOID:13619); alcohol use disorder (Disease Ontology:DOID:1574); rectum cancer (Disease Ontology:DOID:1993); hepatitis B (Disease Ontology:DOID:2043); colon cancer (Disease Ontology:DOID:219); colon adenocarcinoma (Disease Ontology:DOID:234); nephrosis (Disease Ontology:DOID:2527); asthma (Disease Ontology:DOID:2841); pulmonary tuberculosis (Disease Ontology:DOID:2957); acute kidney failure (Disease Ontology:DOID:3021); chronic obstructive pulmonary disease (Disease Ontology:DOID:3083); breast carcinoma (Disease Ontology:DOID:3459); ovary adenocarcinoma (Disease Ontology:DOID:3713); esophagus squamous cell carcinoma (Disease Ontology:DOID:3748); lung carcinoma (Disease Ontology:DOID:3905); lung non-small cell carcinoma (Disease Ontology:DOID:3908); lung adenocarcinoma (Disease Ontology:DOID:3910); cerebrotendinous xanthomatosis (Disease Ontology:DOID:4810); esophagus adenocarcinoma (Disease Ontology:DOID:4914); esophageal cancer (Disease Ontology:DOID:5041); lung small cell carcinoma (Disease Ontology:DOID:5409); ulcerative colitis (Disease Ontology:DOID:8577); Wilson disease (Disease Ontology:DOID:893); colorectal cancer (Disease Ontology:DOID:9256); type 1 diabetes mellitus (Disease Ontology:DOID:9744); obesity (Disease Ontology:DOID:9970)", "pathway": " (dme:Dmel_CG4120)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 37, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0004497 monooxygenase activity;GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "go_cellular_component": "GO:0031966 mitochondrial membrane;GO:0016020 membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "Q9VVR9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VW15-1", "uniprot_id": "ASH1_DROME", "mass": 246266.0, "length": 2226, "protein_name": "Histone-lysine N-methyltransferase ash1", "gene_name": "ash1", "organism": "Fruit fly", "refseq_name": "absent, small, or homeotic discs 1, isoform C", "refseq_ac": "NP_001246834", "gene_names_uniprotkb": "ash1; CG8887; KMT2H", "gene_names_refseq": "ASH-1; ASH1; Ash 1; Ash1; Ash; CG8887; Dmel\\CG8887; ash-1; ash1; ash; dash; l(3)76BDb; l(3)SG29a", "protein_names_uniprotkb": "Histone-lysine N-methyltransferase ash1; 2.1.1.354; Absent small and homeotic disks protein 1; Lysine N-methyltransferase 2H", "protein_names_refseq": "Absent, small or homeotic 1; Absent, small or homeotic discs 1; Absent, small, or homeotic disc 1; CG8887-PC; absent small or homeotic 1; absent, small, or homeotic discs 1, isoform C; ash1-PC; discs absent, small, or homeotic-1", "tax_id": 7227, "disease": "developmental disorder of mental health (Disease Ontology:DOID:0060037); autism spectrum disorder (Disease Ontology:DOID:0060041); autosomal dominant intellectual developmental disorder 52 (Disease Ontology:DOID:0080231); leukemia (Disease Ontology:DOID:1240)", "pathway": " (dme:Dmel_CG8887)", "pathway_count": 1, "publication_count": 16, "publication_id_list": "10454589;10656681;10731132;11094082;12397363;12537569;12537572;13679578;15031712;16497925;16882982;18327897;26957542;7982557;8725238;9735357", "class_list": "", "function": "Trithorax group (TrxG) protein that has histone methyltransferase activity (PubMed:13679578, PubMed:16882982). Specifically trimethylates 'Lys-4' of histone H3 (H3K4me3), a specific tag for epigenetic transcriptional activation (PubMed:13679578, PubMed:16882982). TrxG proteins are generally required to maintain the transcriptionally active state of homeotic genes throughout development. Does not act as a coactivator required for transcriptional activation, but specifically prevents inappropriate Polycomb Group (PcG) silencing of homeotic genes in cells in which they must stay transcriptionally active (PubMed:15031712)., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 8, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 4, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "A8WHI9;M9NFL0;Q24189;Q8MQX5", "ec_number_list": "2.1.1.354", "go_molecular_function": "GO:0003682 chromatin binding;GO:0008270 zinc ion binding;GO:0042054 histone methyltransferase activity;GO:0042800 histone H3K4 methyltransferase activity;GO:0046975 histone H3K36 methyltransferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0000785 chromatin;GO:0035097 histone methyltransferase complex;GO:0032991 protein-containing complex", "go_biological_process": "GO:0010628 positive regulation of gene expression;GO:0006355 regulation of DNA-templated transcription;GO:0045815 transcription initiation-coupled chromatin remodeling;GO:0032259 methylation;GO:0048477 oogenesis", "synthesized_glycan_count": 0, "hit_score": 1.9, "record_id": "Q9VW15-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VW43-1", "uniprot_id": "CP305_DROME", "mass": 57720.0, "length": 504, "protein_name": "Probable cytochrome P450 305a1", "gene_name": "Cyp305a1", "organism": "Fruit fly", "refseq_name": "cytochrome P450 305a1", "refseq_ac": "NP_649151", "gene_names_uniprotkb": "Cyp305a1; CG8733", "gene_names_refseq": "305a1; AAF49108.1; CG8733; CYP305A1-Dm; CYP305A1; Cyp305A1; Cyp305a1; Dmel\\CG8733", "protein_names_uniprotkb": "Probable cytochrome P450 305a1; 1.14.-.-; CYPCCCVA1", "protein_names_refseq": "CG8733-PA; Cyp305a1-PA; cytochrome P450 305a1; cytochrome P450", "tax_id": 7227, "disease": "invasive aspergillosis (Disease Ontology:DOID:0050073); Keshan disease (Disease Ontology:DOID:0050083); alcohol dependence (Disease Ontology:DOID:0050741); nicotine dependence (Disease Ontology:DOID:0050742); renal fibrosis (Disease Ontology:DOID:0050855); hepatocellular adenoma (Disease Ontology:DOID:0050868); alcohol-associated liver disease (Disease Ontology:DOID:0070658); metabolic dysfunction-associated steatotic liver disease (Disease Ontology:DOID:0080208); warfarin resistance (Disease Ontology:DOID:0080665); pre-eclampsia (Disease Ontology:DOID:10591); renal hypertension (Disease Ontology:DOID:1073); hypertension (Disease Ontology:DOID:10763); sickle cell anemia (Disease Ontology:DOID:10923); urinary bladder cancer (Disease Ontology:DOID:11054); familial hyperlipidemia (Disease Ontology:DOID:1168); hypertrophic cardiomyopathy (Disease Ontology:DOID:11984); dilated cardiomyopathy (Disease Ontology:DOID:12930); eosinophilic esophagitis (Disease Ontology:DOID:13922); Plasmodium falciparum malaria (Disease Ontology:DOID:14067); alcohol use disorder (Disease Ontology:DOID:1574); depressive disorder (Disease Ontology:DOID:1596); breast cancer (Disease Ontology:DOID:1612); drug-induced hepatitis (Disease Ontology:DOID:2044); colon cancer (Disease Ontology:DOID:219); acute kidney failure (Disease Ontology:DOID:3021); middle cerebral artery infarction (Disease Ontology:DOID:3525); tuberculosis (Disease Ontology:DOID:399); liver disease (Disease Ontology:DOID:409); hyperglycemia (Disease Ontology:DOID:4195); multiple chemical sensitivity (Disease Ontology:DOID:4661); human immunodeficiency virus infectious disease (Disease Ontology:DOID:526); head and neck squamous cell carcinoma (Disease Ontology:DOID:5520); myocardial infarction (Disease Ontology:DOID:5844); pulmonary hypertension (Disease Ontology:DOID:6432); hepatocellular carcinoma (Disease Ontology:DOID:684); peptic ulcer disease (Disease Ontology:DOID:750); end stage renal disease (Disease Ontology:DOID:783); acute myeloid leukemia (Disease Ontology:DOID:9119); diabetes mellitus (Disease Ontology:DOID:9351); type 2 diabetes mellitus (Disease Ontology:DOID:9352); steatotic liver disease (Disease Ontology:DOID:9452); multiple myeloma (Disease Ontology:DOID:9538); neonatal abstinence syndrome (Disease Ontology:DOID:9828); obesity (Disease Ontology:DOID:9970); drug dependence (Disease Ontology:DOID:9974); heroin dependence (Disease Ontology:DOID:9976); hypoglycemia (Disease Ontology:DOID:9993)", "pathway": " (dme:Dmel_CG8733)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "10731132;12537569;12537572", "class_list": "", "function": "May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 47, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0004497 monooxygenase activity;GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9VW43-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VW71-1", "uniprot_id": "FAT2_DROME", "mass": 523781.0, "length": 4699, "protein_name": "Fat-like cadherin-related tumor suppressor homolog", "gene_name": "kug", "organism": "Fruit fly", "refseq_name": "kugelei, isoform D", "refseq_ac": "NP_001027138", "gene_names_uniprotkb": "kug; CG7749; CT23445; Cad76E; DCad76E; Dmel\\CG7749; Dmel_CG7749; Fat-like; Fat2; Ftl; Kug; RE-A; fat2; fat; ft2; ftl", "gene_names_refseq": "CG7749; CT23445; Cad76E; DCad76E; Dmel\\CG7749; Fat-like; Fat2; Ftl; Kug; RE-A; fat2; fat; ft2; ftl; kug", "protein_names_uniprotkb": "Fat-like cadherin-related tumor suppressor homolog; Protein kugelei", "protein_names_refseq": "CG7749-PD; fat-like; fat2; kug-PD; kugelei, isoform D; kugelei", "tax_id": 7227, "disease": "oral squamous cell carcinoma (Disease Ontology:DOID:0050866); spinocerebellar ataxia 45 (Disease Ontology:DOID:0080287); facioscapulohumeral muscular dystrophy (Disease Ontology:DOID:11727); nephrotic syndrome (Disease Ontology:DOID:1184); esophagus squamous cell carcinoma (Disease Ontology:DOID:3748); lung non-small cell carcinoma (Disease Ontology:DOID:3908); lung small cell carcinoma (Disease Ontology:DOID:5409); colorectal cancer (Disease Ontology:DOID:9256)", "pathway": " (dme:Dmel_CG7749)", "pathway_count": 1, "publication_count": 15, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;19906848;23369713;25589440;26109356;26109357;40245499", "class_list": "", "function": "Required for the planar polarity of actin filament orientation at the basal side of ovarian follicle cells (PubMed:19906848, PubMed:23369713). Required for proper egg chamber shape and elongation of the egg chamber during oogenesis (PubMed:19906848, PubMed:23369713). Required for the correct planar polarization of Rab10 within the basal follicle cell epithelium and is therefore indirectly involved in the Rab10-dependent remodeling of the basal membrane during egg chamber elongation (PubMed:23369713)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 12, "predicted_n_glycosites": 12, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 8, "glyco_site_count": 13, "binding_glycan_count": 0, "secondary_ac_list": "A4V252;Q95S51", "ec_number_list": "", "go_molecular_function": "GO:0005509 calcium ion binding;GO:0050839 cell adhesion molecule binding;GO:0044877 protein-containing complex binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005912 adherens junction;GO:0005925 focal adhesion;GO:0009925 basal plasma membrane;GO:0031254 cell trailing edge", "go_biological_process": "GO:0007442 hindgut morphogenesis;GO:0042247 establishment of planar polarity of follicular epithelium;GO:0050829 defense response to Gram-negative bacterium;GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules;GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules", "synthesized_glycan_count": 0, "hit_score": 1.8, "record_id": "Q9VW71-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VWA8-1", "uniprot_id": "FRG1_DROME", "mass": 29530.0, "length": 262, "protein_name": "Protein FRG1 homolog", "gene_name": "FRG1", "organism": "Fruit fly", "refseq_name": "FSHD region gene 1", "refseq_ac": "NP_649202", "gene_names_uniprotkb": "FRG1; CG6480", "gene_names_refseq": "CG6480; DmFRG1; Dmel\\CG6480; FRG1; dFRG1", "protein_names_uniprotkb": "Protein FRG1 homolog", "protein_names_refseq": "CG6480-PA; FRG1-PA; FSHD region gene 1 ortholog; FSHD region gene 1", "tax_id": 7227, "disease": "facioscapulohumeral muscular dystrophy (Disease Ontology:DOID:11727)", "pathway": " (dme:Dmel_CG6480)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "10731132;12537572;23720823", "class_list": "", "function": "May have a role in processing of pre-rRNA or in the assembly of rRNA into ribosomal subunits (By similarity). May be involved in epigenetic regulation of muscle differentiation through regulation of the activity of the histone-lysine N-methyltransferase Suv4-20., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q4V3U4", "ec_number_list": "", "go_molecular_function": "GO:0051015 actin filament binding", "go_cellular_component": "GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0030018 Z disc;GO:0015030 Cajal body;GO:0071013 catalytic step 2 spliceosome", "go_biological_process": "GO:0007517 muscle organ development;GO:0006364 rRNA processing;GO:0070828 heterochromatin organization", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9VWA8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VWE0-1", "uniprot_id": "DOME_DROME", "mass": 142361.0, "length": 1282, "protein_name": "Cytokine receptor", "gene_name": "dome", "organism": "Fruit fly", "refseq_name": "domeless", "refseq_ac": "NP_523412", "gene_names_uniprotkb": "dome; CG14226", "gene_names_refseq": "142932_at; CG14226; CT33841; DOME; Dmel\\CG14226; Domeless; Dome; Dom; anon-18DEb; domeMESO; dome; l(1)G0217; l(1)G0218; l(1)G0264; l(1)G0282; l(1)G0321; l(1)G0367; l(1)G0405; l(1)G0441; l(1)G0468; mom; vsp", "protein_names_uniprotkb": "Cytokine receptor; Protein domeless", "protein_names_refseq": "CG14226-PA; dome receptor; dome-PA; domeless; master of marelle; verstopft", "tax_id": 7227, "disease": "viral infectious disease (Disease Ontology:DOID:934)", "pathway": " (dme:Dmel_CG14226); (R-DME-209209); (R-DME-209228); (R-DME-210688); (R-DME-6798695)", "pathway_count": 5, "publication_count": 23, "publication_id_list": "10731132;10823841;11696329;11825879;12403714;12537569;12537572;12783781;12967563;15925495;16055650;16094372;16129580;16277982;16477645;18327897;25923769;8463208;8608596;9047382;9620640;9671298;9784499", "class_list": "", "function": "Critical for epithelial morphogenesis during oogenesis; border cell migration. Required in the germarium for the polarization of follicle cells during encapsulation of germline cells. Required for embryonic segmentation and trachea specification. Essential receptor molecule for upd and JAK/STAT signaling during oogenesis., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 24, "predicted_n_glycosites": 23, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 24, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0097677 STAT family protein binding;GO:0046982 protein heterodimerization activity;GO:1990782 protein tyrosine kinase binding;GO:0004896 cytokine receptor activity;GO:0097678 SOCS family protein binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016324 apical plasma membrane;GO:0016327 apicolateral plasma membrane", "go_biological_process": "GO:0007442 hindgut morphogenesis;GO:0008284 positive regulation of cell population proliferation;GO:0050829 defense response to Gram-negative bacterium;GO:0042246 tissue regeneration;GO:0007616 long-term memory", "synthesized_glycan_count": 0, "hit_score": 2.4, "record_id": "Q9VWE0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VWE6-1", "uniprot_id": "ELYS_DROME", "mass": 235187.0, "length": 2111, "protein_name": "Protein ELYS homolog", "gene_name": "Elys", "organism": "Fruit fly", "refseq_name": "elys, isoform B", "refseq_ac": "NP_001285454", "gene_names_uniprotkb": "Elys; CG14215; Dmel\\CG14215; Dmel_CG14215; ELYS; dElys; elys", "gene_names_refseq": "CG14215; Dmel\\CG14215; ELYS; Elys; dElys; elys", "protein_names_uniprotkb": "Protein ELYS homolog", "protein_names_refseq": "CG14215-PB; Elys-PB; elys, isoform B", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG14215); (R-DME-9615933)", "pathway_count": 2, "publication_count": 19, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17372656;17569856;17569867;18327897;25589440;26109356;26109357;28366641;28472469;29773558;31784359;40245499", "class_list": "", "function": "Component of the nuclear pore complex (PubMed:28366641, PubMed:29773558). Binds to transcriptionally active chromatin including regulatory regions (PubMed:28366641, PubMed:31784359)., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 29, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "Q95TR2", "ec_number_list": "", "go_molecular_function": "GO:0003682 chromatin binding;GO:0031490 chromatin DNA binding", "go_cellular_component": "GO:0005635 nuclear envelope;GO:0005643 nuclear pore;GO:0005694 chromosome;GO:0005634 nucleus", "go_biological_process": "GO:0006913 nucleocytoplasmic transport;GO:0015031 protein transport;GO:0051028 mRNA transport", "synthesized_glycan_count": 0, "hit_score": 2.2, "record_id": "Q9VWE6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VWF4-1", "uniprot_id": "DUSK4_DROME", "mass": 43742.0, "length": 387, "protein_name": "Dual specificity protein phosphatase MPK-4", "gene_name": "MKP-4", "organism": "Fruit fly", "refseq_name": "MAPK phosphatase 4, isoform C", "refseq_ac": "NP_001259717", "gene_names_uniprotkb": "MKP-4; CG14211", "gene_names_refseq": "CG14211; DMKP-4; Dmel\\CG14211; MAPK; MKP-4; Mkp4", "protein_names_uniprotkb": "Dual specificity protein phosphatase MPK-4; 3.1.3.16; 3.1.3.48", "protein_names_refseq": "CG14211-PC; MAPK phosphatase 4, isoform C; MKP-4-PC; MKP-like", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG14211)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "10731132;12537569;12537572;18456458", "class_list": "", "function": "Dual specificity phosphatase; can dephosphorylate both phosphotyrosine and phosphoserine or phosphothreonine residues. May suppress bsk/JNK activation during the immune response., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q95TD9", "ec_number_list": "3.1.3.16;3.1.3.48;3.1.3.-;3.1.3.2;3.1.3.27", "go_molecular_function": "GO:0004722 protein serine/threonine phosphatase activity;GO:0008138 protein tyrosine/serine/threonine phosphatase activity;GO:0016791 phosphatase activity;GO:0004725 protein tyrosine phosphatase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0043409 negative regulation of MAPK cascade", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q9VWF4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VWH4-1", "uniprot_id": "IDH3A_DROME", "mass": 40844.0, "length": 377, "protein_name": "Probable isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial", "gene_name": "Idh3a", "organism": "Fruit fly", "refseq_name": "isocitrate dehydrogenase 3a, isoform D", "refseq_ac": "NP_001259705", "gene_names_uniprotkb": "Idh3a; CG12233; l(1)G0156", "gene_names_refseq": "CG12233; Dmel\\CG12233; IDH3A; Idh3a; dIDH3a; idh3a; l (1) G0156; l(1)G0156; lethal (1) G0156", "protein_names_uniprotkb": "Probable isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial; 1.1.1.41; Isocitric dehydrogenase subunit alpha; NAD(+)-specific ICDH subunit alpha", "protein_names_refseq": "CG12233-PD; Idh3a-PD; Lethal(1)G0156; isocitrate dehydrogenase 3a, isoform D; isocitrate dehydrogenase 3a; l(1)G0156; lethal (1) G0156", "tax_id": 7227, "disease": "early infantile epileptic encephalopathy (Disease Ontology:DOID:0050709); retinitis pigmentosa 90 (Disease Ontology:DOID:0112147); neuromuscular junction disease (Disease Ontology:DOID:439)", "pathway": " (dme:Dmel_CG12233); (R-DME-71403); (R-DME-9837999)", "pathway_count": 3, "publication_count": 3, "publication_id_list": "10731132;12537569;12537572", "class_list": "", "function": "Probable catalytic subunit of the enzyme which catalyzes the decarboxylation of isocitrate (ICT) into alpha-ketoglutarate., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "E4NKP2;Q8IQW9;Q8SXH8", "ec_number_list": "1.1.1.40;1.1.1.38;1.1.1.39;1.2.4.2;2.3.1.37;3.5.3.1;2.7.11.2;2.7.11.-;7.1.2.2;1.2.4.1;7.1.1.2;6.2.1.4;4.98.1.1;1.-.-.-;1.1.1.62;1.1.1.239;1.1.1.37;4.2.1.3;3.4.21.92;1.2.1.3;1.8.1.4;1.1.1.41;2.8.3.5;2.3.-.-;2.3.1.-;2.3.1.9;4.2.1.2;2.3.3.16;5.3.3.21", "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0051287 NAD binding;GO:0004449 isocitrate dehydrogenase (NAD+) activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix;GO:0045242 isocitrate dehydrogenase complex (NAD+)", "go_biological_process": "GO:0006099 tricarboxylic acid cycle;GO:0006102 isocitrate metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9VWH4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VWN4-1", "uniprot_id": "FLACC_DROME", "mass": 128975.0, "length": 1150, "protein_name": "Fl(2)d-associated complex component", "gene_name": "Flacc", "organism": "Fruit fly", "refseq_name": "Fl(2)d-associated complex component, isoform B", "refseq_ac": "NP_001285418", "gene_names_uniprotkb": "Flacc; CG7358; Xio", "gene_names_refseq": "CG7358; Dmel\\CG7358; Flacc; flacc; xio", "protein_names_uniprotkb": "Fl(2)d-associated complex component; Protein Xiong", "protein_names_refseq": "CG7358-PB; Fl(2)d-associated complex component, isoform B; Flacc-PB; xiong", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG7358)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "10731132;12537569;12537572;29535189;29555755", "class_list": "", "function": "Associated component of the WMM complex, a complex that mediates N6-methyladenosine (m6A) methylation of mRNAs, a modification that plays a role in the efficiency of mRNA splicing and is required for sex determination (PubMed:29535189, PubMed:29555755). In the WMM complex, acts as a key regulator of m6A methylation by bridging fl(2)d to the RNA-binding component nito (PubMed:29535189). Required for sex determination and dosage compensation via Sxl alternative splicing: m6A methylation acts as a key regulator of Sxl pre-mRNA and promotes female-specific alternative splicing of Sxl, which determines female physiognomy (PubMed:29535189, PubMed:29555755)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "X2JFQ1;X2JG10", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0036396 RNA N6-methyladenosine methyltransferase complex;GO:0005634 nucleus", "go_biological_process": "GO:0007530 sex determination;GO:0006397 mRNA processing;GO:0016556 mRNA modification;GO:0030154 cell differentiation;GO:0008380 RNA splicing", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q9VWN4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VWR2-1", "uniprot_id": "CP308_DROME", "mass": 55713.0, "length": 490, "protein_name": "Probable cytochrome P450 308a1", "gene_name": "Cyp308a1", "organism": "Fruit fly", "refseq_name": "cytochrome P450 308a1", "refseq_ac": "NP_573320", "gene_names_uniprotkb": "Cyp308a1; CG6585", "gene_names_refseq": "308a1; CG6585; Cyp308a1; Dmel\\CG6585", "protein_names_uniprotkb": "Probable cytochrome P450 308a1; 1.14.-.-; CYPCCCVIIIA1", "protein_names_refseq": "CG6585-PA; Cyp308a1-PA; cytochrome P450 308a1", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG6585)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "10731132;12537572", "class_list": "", "function": "May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q1RKQ7", "ec_number_list": "", "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0004497 monooxygenase activity;GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q9VWR2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VWR8-1", "uniprot_id": "DPY19_DROME", "mass": 101097.0, "length": 872, "protein_name": "C-mannosyltransferase dpy-19 homolog", "gene_name": "CG6659", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform A", "refseq_ac": "NP_573317", "gene_names_uniprotkb": "CG6659", "gene_names_refseq": "CG6659; Dmel\\CG6659", "protein_names_uniprotkb": "C-mannosyltransferase dpy-19 homolog; 2.4.1.-", "protein_names_refseq": "CG6659-PA; uncharacterized protein, isoform A", "tax_id": 7227, "disease": "spermatogenic failure 9 (Disease Ontology:DOID:0111156)", "pathway": " (dme:Dmel_CG6659)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "10731132;12537569;12537572", "class_list": "", "function": "Probable C-mannosyltransferase that mediates C-mannosylation of tryptophan residues on target proteins., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q7KUV6;Q9VWR9", "ec_number_list": "", "go_molecular_function": "GO:0000030 mannosyltransferase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0018103 protein C-linked glycosylation", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9VWR8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VWS4-1", "uniprot_id": "WGN_DROME", "mass": 37829.0, "length": 343, "protein_name": "Tumor necrosis factor receptor superfamily member wgn", "gene_name": "wgn", "organism": "Fruit fly", "refseq_name": "wengen, isoform A", "refseq_ac": "NP_728186", "gene_names_uniprotkb": "wgn; CG6531; Dmel\\CG6531; Dmel_CG6531; TNFR; Vader; Wengen; Wgn; Wng; vader", "gene_names_refseq": "CG6531; Dmel\\CG6531; TNFR; Wengen; Wgn; Wng; vader; wgn", "protein_names_uniprotkb": "Tumor necrosis factor receptor superfamily member wgn; Protein wengen", "protein_names_refseq": "CG6531-PA; TNF-alpha receptor; wengen, isoform A; wengen; wgn-PA", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG6531)", "pathway_count": 1, "publication_count": 19, "publication_id_list": "10731132;12084706;12537568;12537569;12537572;12537573;12537574;12894227;16110336;17569856;17569867;19289090;19375319;23544124;25589440;26109356;26109357;33824334;38944657", "class_list": "", "function": "Receptor for egr (PubMed:12084706, PubMed:12894227, PubMed:33824334). Involved in induction of apoptosis by triggering JNK signaling (PubMed:12894227). Mediates the tumor suppressor activity of egr which eliminates oncogenic cells from epithelia, thereby maintaining epithelial integrity (PubMed:19289090). Following UV-induced epidermal damage, binds to egr released from apoptotic epidermal cells and plays a role in development of thermal allodynia, a responsiveness to subthreshold thermal stimuli which are not normally perceived as noxious (PubMed:19375319). Together with Moe, involved in control of axon targeting of R8 and R2-R5 photoreceptors, independent of egr (PubMed:23544124)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q7Z1X1", "ec_number_list": "", "go_molecular_function": "GO:0005031 tumor necrosis factor receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0009986 cell surface;GO:0030659 cytoplasmic vesicle membrane", "go_biological_process": "GO:0070050 neuron cellular homeostasis;GO:0006915 apoptotic process;GO:0033209 tumor necrosis factor-mediated signaling pathway;GO:0043068 positive regulation of programmed cell death;GO:0072499 photoreceptor cell axon guidance", "synthesized_glycan_count": 0, "hit_score": 2.0, "record_id": "Q9VWS4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VWW0-3", "uniprot_id": "CREBB_DROME", "mass": 34931.0, "length": 331, "protein_name": "Cyclic AMP response element-binding protein B", "gene_name": "CrebB", "organism": "Fruit fly", "refseq_name": "Cyclic-AMP response element binding protein B, isoform P", "refseq_ac": "NP_001097016", "gene_names_uniprotkb": "CrebB; CG6103; CrebB-17A", "gene_names_refseq": "CG6103; CRE-BP; CREB-B; CREB-b; CREB2-b; CREB2a; CREB2b; CREB2; CREB; Creb B 17A; Creb-B; Creb17A; Creb2-b; Creb2.b; Creb2b; Creb2; CrebB-17A; CrebB-17B; CrebB17-A; CrebB; Creb; DM9; Dmel\\CG6103; FBgn0014467; S162; creb2; crebB; dCREB-2a; dCREB-2; dCREB-B; dCREB2-a; dCREB2-b; dCREB2a; dCREB2b; dCREB2; dCREB; dCbz; dCreb2-b; dCreb2b; dCreb2; dCrebB2; dcreb2-b; l(1)17Af", "protein_names_uniprotkb": "Cyclic AMP response element-binding protein B; cAMP response element-binding protein B; dCREB-B", "protein_names_refseq": "CG6103-PP; CREB; CrebB-PP; Cyclic-AMP response element binding protein B at 17A; Cyclic-AMP response element binding protein B at 17B; Cyclic-AMP response element binding protein B, isoform P; activator; blocker; cAMP response element binding; cAMP response element-binding protein; cAMP response-element binding protein; cAMP-regulated enhancer-binding protein; cAMP-response element binding protein; cAMP-response element-binding protein; cyclic AMP response element binding protein; dCREB2; lethal(1)17Af", "tax_id": 7227, "disease": "alcohol dependence (Disease Ontology:DOID:0050741); nicotine dependence (Disease Ontology:DOID:0050742); withdrawal disorder (Disease Ontology:DOID:0060001); autism spectrum disorder (Disease Ontology:DOID:0060041); polycystic kidney disease (Disease Ontology:DOID:0080322); hypertension (Disease Ontology:DOID:10763); amnestic disorder (Disease Ontology:DOID:10914); obsessive-compulsive disorder (Disease Ontology:DOID:10933); opioid abuse (Disease Ontology:DOID:11206); sciatic neuropathy (Disease Ontology:DOID:11446); Pick's disease (Disease Ontology:DOID:11870); Huntington's disease (Disease Ontology:DOID:12858); Parkinson's disease (Disease Ontology:DOID:14330); alcohol use disorder (Disease Ontology:DOID:1574); depressive disorder (Disease Ontology:DOID:1596); anxiety disorder (Disease Ontology:DOID:2030); transient cerebral ischemia (Disease Ontology:DOID:224); brain ischemia (Disease Ontology:DOID:2316); morphine dependence (Disease Ontology:DOID:2560); middle cerebral artery infarction (Disease Ontology:DOID:3525); schizophrenia (Disease Ontology:DOID:5419); congestive heart failure (Disease Ontology:DOID:6000); amphetamine abuse (Disease Ontology:DOID:670); cocaine abuse (Disease Ontology:DOID:809); vascular dementia (Disease Ontology:DOID:8725); type 2 diabetes mellitus (Disease Ontology:DOID:9352); substance dependence (Disease Ontology:DOID:9973); drug dependence (Disease Ontology:DOID:9974); cocaine dependence (Disease Ontology:DOID:9975); heroin dependence (Disease Ontology:DOID:9976)", "pathway": " (dme:Dmel_CG6103); (R-DME-198693); (R-DME-199920); (R-DME-375165); (R-DME-442742); (R-DME-881907); (R-DME-9634638)", "pathway_count": 7, "publication_count": 7, "publication_id_list": "10731132;12537572;15219829;18327897;29473541;7651429;8397816", "class_list": "", "function": "Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters (PubMed:15219829, PubMed:7651429). Has a role in long-term memory (PubMed:29473541)., [UniProtKB, PubMed, PubMed, PubMed]; Direct antagonist of activation by isoform E in cell culture., [UniProtKB, PubMed]; PKA-dependent transcriptional activator., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 30, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A1Z1CK36;A8JUN2;A8JUN4;C6SUU1;M9PHW9;M9PHZ6;Q0IGS5;Q0IGV7;Q26329;Q26446;Q7KUW0;Q7KUW1;Q8IQY4", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0043565 sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005667 transcription regulator complex", "go_biological_process": "GO:0045187 regulation of circadian sleep/wake cycle, sleep;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0007528 neuromuscular junction development;GO:0007611 learning or memory", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q9VWW0-3", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VX31-1", "uniprot_id": "INT2_DROME", "mass": 124890.0, "length": 1105, "protein_name": "Integrator complex subunit 2", "gene_name": "IntS2", "organism": "Fruit fly", "refseq_name": "integrator 2", "refseq_ac": "NP_573232", "gene_names_uniprotkb": "IntS2; CG8211", "gene_names_refseq": "CG8211; Dmel\\CG8211; Int2; IntS2; intS2", "protein_names_uniprotkb": "Integrator complex subunit 2", "protein_names_refseq": "CG8211-PA; IntS2-PA; integrator 2", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG8211); (R-DME-6807505)", "pathway_count": 2, "publication_count": 8, "publication_id_list": "10731132;12537572;21078872;23097424;31530651;32966759;37995689;39032490", "class_list": "", "function": "Component of the integrator complex, a multiprotein complex that terminates RNA polymerase II (Pol II) transcription in the promoter-proximal region of genes (PubMed:21078872, PubMed:23097424, PubMed:32966759). The integrator complex provides a quality checkpoint during transcription elongation by driving premature transcription termination of transcripts that are unfavorably configured for transcriptional elongation: the complex terminates transcription by (1) catalyzing dephosphorylation of the C-terminal domain (CTD) of Pol II subunit Polr2A/Rbp1 and Spt5, and (2) degrading the exiting nascent RNA transcript via endonuclease activity (PubMed:32966759). The integrator complex is also involved in the 3'-end processing of the U7 snRNA, and also the spliceosomal snRNAs U1, U2, U4 and U5 (PubMed:21078872, PubMed:23097424)., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0031965 nuclear membrane;GO:0032039 integrator complex;GO:0160232 INTAC complex", "go_biological_process": "GO:0010628 positive regulation of gene expression;GO:0045666 positive regulation of neuron differentiation;GO:0016180 snRNA processing;GO:0034472 snRNA 3'-end processing;GO:0160240 RNA polymerase II transcription initiation surveillance", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q9VX31-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VX36-1", "uniprot_id": "Q9VX36_DROME", "mass": 26782.0, "length": 242, "protein_name": "1.-.-.-; NADH dehydrogenase (Ubiquinone) 24 kDa subunit, isoform A; NADH dehydrogenase (Ubiquinone) 24 kDa subunit, isoform B", "gene_name": "ND-24", "organism": "Fruit fly", "refseq_name": "NADH dehydrogenase (ubiquinone) 24 kDa subunit, isoform B", "refseq_ac": "NP_001285378", "gene_names_uniprotkb": "ND-24; BEST:LP01573; CG 5703; CG5703; Dmel\\CG5703; Dmel_CG5703; ND24; NDUFV2; NUHM; Ndufv2; Q9VX36; dNDUFV2A; dNDUFV2", "gene_names_refseq": "BEST:LP01573; CG 5703; CG5703; Dmel\\CG5703; ND-24; ND24; NDUFV2; NUHM; Ndufv2; Q9VX36; dNDUFV2A; dNDUFV2", "protein_names_uniprotkb": "1.-.-.-; NADH dehydrogenase (Ubiquinone) 24 kDa subunit, isoform A; NADH dehydrogenase (Ubiquinone) 24 kDa subunit, isoform B", "protein_names_refseq": "CG5703-PB; COMPLEX I: 24 kDa subunit; NADH dehydrogenase (ubiquinone) 24 kDa subunit, isoform B; NADH dehydrogenase ubiquinone flavoprotein 2; NADH ubiquinone oxidoreductase 24 kDa; NADH-ubiquinone oxidoreductase 24 kDa subunit; NADH:ubiquinone oxidoreductase 24 kDa subunit; ND-24-PB", "tax_id": 7227, "disease": "nuclear type mitochondrial complex I deficiency 7 (Disease Ontology:DOID:0112092); Parkinson's disease (Disease Ontology:DOID:14330); mitochondrial metabolism disease (Disease Ontology:DOID:700)", "pathway": " (dme:Dmel_CG5703); (R-DME-611105); (R-DME-6799198)", "pathway_count": 3, "publication_count": 13, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357;36622099;36952377", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "7.1.1.2;2.1.1.320;1.-.-.-", "go_molecular_function": "GO:0046872 metal ion binding;GO:0051537 2 iron, 2 sulfur cluster binding;GO:0016491 oxidoreductase activity;GO:0008137 NADH dehydrogenase (ubiquinone) activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane;GO:0045271 respiratory chain complex I", "go_biological_process": "GO:0006120 mitochondrial electron transport, NADH to ubiquinone", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "Q9VX36-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VX98-1", "uniprot_id": "DENR_DROME", "mass": 21349.0, "length": 189, "protein_name": "Density-regulated protein homolog", "gene_name": "DENR", "organism": "Fruit fly", "refseq_name": "density regulated protein, isoform B", "refseq_ac": "NP_001259630", "gene_names_uniprotkb": "DENR; CG9099", "gene_names_refseq": "CG9099; DENR; Dmel\\CG9099", "protein_names_uniprotkb": "Density-regulated protein homolog", "protein_names_refseq": "CG9099-PB; DENR-PB; density regulated protein, isoform B", "tax_id": 7227, "disease": "autism spectrum disorder (Disease Ontology:DOID:0060041)", "pathway": " (dme:Dmel_CG9099)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "10731132;12537569;12537572;25043021", "class_list": "", "function": "Regulates translation as part of a complex with MCTS1. Specifically required for translational re-initiation in mRNAs containing upstream open reading frames (uORFs). Not required for standard translational initiation. Regulates expression of a subset of gene products including mbc, InR and EcR., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q95SJ6", "ec_number_list": "", "go_molecular_function": "GO:0003743 translation initiation factor activity;GO:0048027 mRNA 5'-UTR binding", "go_cellular_component": "GO:0032991 protein-containing complex", "go_biological_process": "GO:0002188 translation reinitiation;GO:0006417 regulation of translation;GO:0046628 positive regulation of insulin receptor signaling pathway;GO:0001731 formation of translation preinitiation complex;GO:0120142 positive regulation of ecdysone receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q9VX98-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VXA8-1", "uniprot_id": "DXO_DROME", "mass": 42903.0, "length": 375, "protein_name": "Decapping and exoribonuclease protein Rai1", "gene_name": "Rai1", "organism": "Fruit fly", "refseq_name": "Rat1 interacting protein 1", "refseq_ac": "NP_996492", "gene_names_uniprotkb": "Rai1; CG9125", "gene_names_refseq": "CG32566; CG9125; Dmel\\CG9125; Rai1; dRai1", "protein_names_uniprotkb": "Decapping and exoribonuclease protein Rai1; 3.1.13.-; 3.6.1.-; DXO; DeNADding enzyme; Dom-3 homolog Z; Dom3Z; NAD-capped RNA hydrolase", "protein_names_refseq": "CG9125-PA; Rai1-PA; Rat1 interacting protein 1", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG9125)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "10731132;12537572;19126864;27292797", "class_list": "", "function": "Decapping enzyme for NAD-capped RNAs: specifically hydrolyzes the nicotinamide adenine dinucleotide (NAD) cap from a subset of RNAs by removing the entire NAD moiety from the 5'-end of an NAD-capped RNA. The NAD-cap is present at the 5'-end of some RNAs and snoRNAs. In contrast to the canonical 5'-end N7 methylguanosine (m7G) cap, the NAD cap promotes mRNA decay. Also acts as a non-canonical decapping enzyme that removes the entire cap structure of m7G capped or incompletely capped RNAs and mediates their subsequent degradation. Specifically degrades pre-mRNAs with a defective 5'-end m7G cap and is part of a pre-mRNA capping quality control. Possesses 5'-pyrophosphohydrolase activity, hydrolyzing the 5'-end triphosphate to release pyrophosphates, and 5'-3' exonuclease activity (PubMed:27292797). May be involved in RNA degradation in the nucleus (PubMed:27292797)., [UniProtKB, UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.1.13.-;3.6.1.-", "go_molecular_function": "GO:0034353 mRNA 5'-diphosphatase activity;GO:0003723 RNA binding;GO:0046872 metal ion binding;GO:0000166 nucleotide binding;GO:0004534 5'-3' RNA exonuclease activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol", "go_biological_process": "GO:0006402 mRNA catabolic process;GO:0000956 nuclear-transcribed mRNA catabolic process;GO:0110155 NAD-cap decapping", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q9VXA8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VXG4-1", "uniprot_id": "ANX11_DROME", "mass": 56215.0, "length": 511, "protein_name": "Annexin B11", "gene_name": "AnxB11", "organism": "Fruit fly", "refseq_name": "annexin B11, isoform C", "refseq_ac": "NP_001259614", "gene_names_uniprotkb": "AnxB11; CG9968", "gene_names_refseq": "ANXB11; AnxB11; Anxb11; Axb11; BcDNA:GH16395; CG9968; Dmel\\CG9968; annexin", "protein_names_uniprotkb": "Annexin B11", "protein_names_refseq": "AnxB11-PC; CG9968-PC; annexin B11, isoform C; annexin B11", "tax_id": 7227, "disease": "non-Hodgkin lymphoma (Disease Ontology:DOID:0060060); amyotrophic lateral sclerosis type 23 (Disease Ontology:DOID:0080225); inclusion body myopathy and brain white matter abnormalities (Disease Ontology:DOID:0081121); prostate cancer (Disease Ontology:DOID:10283); cryptorchidism (Disease Ontology:DOID:11383); hypothyroidism (Disease Ontology:DOID:1459); breast cancer (Disease Ontology:DOID:1612); colon adenocarcinoma (Disease Ontology:DOID:234); ovarian cancer (Disease Ontology:DOID:2394); glomerulonephritis (Disease Ontology:DOID:2921); skin cancer (Disease Ontology:DOID:4159); myocardial infarction (Disease Ontology:DOID:5844); hyperthyroidism (Disease Ontology:DOID:7998); Wilson disease (Disease Ontology:DOID:893)", "pathway": " (dme:Dmel_CG9968)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "10731132;12537569;12537572", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 14, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "M9PEV0;M9PHW3;Q9VXG3", "ec_number_list": "", "go_molecular_function": "GO:0005509 calcium ion binding;GO:0005544 calcium-dependent phospholipid binding;GO:0001786 phosphatidylserine binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0012506 vesicle membrane", "go_biological_process": "GO:0051592 response to calcium ion", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9VXG4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VXG8-1", "uniprot_id": "ATR_DROME", "mass": 289330.0, "length": 2517, "protein_name": "Serine/threonine-protein kinase ATR", "gene_name": "mei-41", "organism": "Fruit fly", "refseq_name": "meiotic 41", "refseq_ac": "NP_523369", "gene_names_uniprotkb": "mei-41; CG4252", "gene_names_refseq": "4252; ATR; CG4252; DmATR; Dmel\\CG4252; Dmmei41; MEI41/FRP1; MEI41; Mei-41/DATR; Mei-41; Mei41; atr; dATR; fs(1)M37; mei-195; mei-41; mei41; meiP41; mus(1)103; mus(1)104; mus-103; mus-104; mus103; mus104", "protein_names_uniprotkb": "Serine/threonine-protein kinase ATR; 2.7.11.1; ATR homolog; Ataxia telangiectasia and Rad3-related protein homolog; Meiotic protein 41; dATR", "protein_names_refseq": "ATM-RAD3 related; CG4252-PA; ataxia telangiectasia and Rad3 related; drosophila ATR; mei-41-PA; meiotic 41; meiotic-41", "tax_id": 7227, "disease": "Seckel syndrome (Disease Ontology:DOID:0050569); non-Hodgkin lymphoma (Disease Ontology:DOID:0060060); Seckel syndrome 1 (Disease Ontology:DOID:0070007); adenoid cystic carcinoma (Disease Ontology:DOID:0080202); Alzheimer's disease (Disease Ontology:DOID:10652); ataxia telangiectasia (Disease Ontology:DOID:12704); lung cancer (Disease Ontology:DOID:1324); endometrial cancer (Disease Ontology:DOID:1380); breast cancer (Disease Ontology:DOID:1612); pancreatic cancer (Disease Ontology:DOID:1793); colon cancer (Disease Ontology:DOID:219); nasopharynx carcinoma (Disease Ontology:DOID:9261)", "pathway": " (dme:Dmel_CG4252); (R-DME-176187); (R-DME-69473)", "pathway_count": 3, "publication_count": 14, "publication_id_list": "10209095;10731132;11676920;12361566;12537572;12689597;12807779;14711410;14729967;15860729;18327897;19240120;29746464;7671309", "class_list": "", "function": "Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates various proteins, which collectively inhibits DNA replication and mitosis and promotes DNA repair and recombination. Phosphorylates grp/CHK1. Phosphorylates 'Ser-137' of histone variant H2AX/H2AV at sites of DNA damage, thereby regulating DNA damage response mechanism. Essential for the DNA damage checkpoint in larval imaginal disks and neuroblasts and for the DNA replication checkpoint in the embryo. Also has an essential role during early nuclear divisions in embryos, where it is required to delay mitosis in response to incomplete DNA replication. Also plays an important role during meiosis, where it may monitor double-strand-break repair during meiotic crossing over, to regulate the progression of prophase I, and to enforce metaphase I delay observed at the end of oogenesis. Involved in telomere maintenance and prevention of telomere fusion; potentially functioning downstream of moi/modigliani (PubMed:19240120)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 7, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 12, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q24135", "ec_number_list": "2.7.11.17;2.7.11.1;2.7.11.13;2.7.11.24;2.7.11.22;2.7.11.21;5.6.1.8;2.7.11.11;2.7.11.23;2.7.12.1;3.6.4.12;2.7.11.25;2.7.11.12;2.7.12.2;2.7.10.2;5.6.2.4;2.7.11.39", "go_molecular_function": "GO:0003677 DNA binding;GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005694 chromosome", "go_biological_process": "GO:0016321 female meiosis chromosome segregation;GO:0045002 double-strand break repair via single-strand annealing;GO:0006281 DNA repair;GO:0000723 telomere maintenance;GO:0006302 double-strand break repair", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "Q9VXG8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VXJ0-1", "uniprot_id": "DHB4_DROME", "mass": 64073.0, "length": 598, "protein_name": "Peroxisomal multifunctional enzyme type 2", "gene_name": "Mfe2", "organism": "Fruit fly", "refseq_name": "peroxisomal multifunctional enzyme type 2, isoform B", "refseq_ac": "NP_001285318", "gene_names_uniprotkb": "Mfe2; CG3415; DBP; DmMFE-2; Dmel\\CG3415; Dmel_CG3415; HSD17B4; MFE-2; MFE2", "gene_names_refseq": "CG3415; DBP; DmMFE-2; Dmel\\CG3415; HSD17B4; MFE-2; MFE2; Mfe2", "protein_names_uniprotkb": "Peroxisomal multifunctional enzyme type 2; DmMFE-2", "protein_names_refseq": "CG3415-PB; Mfe2-PB; multifunctional enzyme type 2; peroxisomal multifunctional enzyme type 2, isoform B; peroxisomal multifunctional enzyme type 2", "tax_id": 7227, "disease": "Perrault syndrome (Disease Ontology:DOID:0050857); D-bifunctional protein deficiency (Disease Ontology:DOID:0090031); hypertension (Disease Ontology:DOID:10763); Stiff-Person syndrome (Disease Ontology:DOID:13366); lipid metabolism disorder (Disease Ontology:DOID:3146); obesity (Disease Ontology:DOID:9970)", "pathway": " (dme:Dmel_CG3415); (R-DME-193368); (R-DME-2046106); (R-DME-389887); (R-DME-390247); (R-DME-9033241)", "pathway_count": 6, "publication_count": 13, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;21320074;25589440;26109356;26109357", "class_list": "", "function": "Bifunctional enzyme acting on the peroxisomal beta-oxidation pathway for fatty acids., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 6, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.1.1.n12;4.2.1.119", "go_molecular_function": "GO:0004303 estradiol 17-beta-dehydrogenase [NAD(P)+] activity;GO:0080023 (2E)-enoyl-CoA hydratase activity;GO:0106386 (3R)-3-hydroxyacyl-CoA dehydrogenase (NAD+) activity;GO:0016491 oxidoreductase activity;GO:0018812 3-hydroxyacyl-CoA dehydratase activity", "go_cellular_component": "GO:0005777 peroxisome", "go_biological_process": "GO:0006635 fatty acid beta-oxidation;GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "Q9VXJ0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VXT2-1", "uniprot_id": "DJC25_DROME", "mass": 39887.0, "length": 333, "protein_name": "DnaJ homolog subfamily C member 25 homolog", "gene_name": "CG7872", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": "NP_573044", "gene_names_uniprotkb": "CG7872", "gene_names_refseq": "CG7872; Dmel\\CG7872", "protein_names_uniprotkb": "DnaJ homolog subfamily C member 25 homolog", "protein_names_refseq": "CG7872-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG7872)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "10731132;12537569;12537572", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane;GO:0012505 endomembrane system", "go_biological_process": "GO:0006457 protein folding", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9VXT2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VXT5-1", "uniprot_id": "C19L2_DROME", "mass": 78149.0, "length": 687, "protein_name": "CWF19-like protein 2 homolog", "gene_name": "Dmel\\CG9213", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform B", "refseq_ac": "NP_001285277", "gene_names_uniprotkb": "Dmel\\CG9213; CG32585; CG9213; Dmel_CG9213", "gene_names_refseq": "CG32585; CG9213; Dmel\\CG9213", "protein_names_uniprotkb": "CWF19-like protein 2 homolog", "protein_names_refseq": "CG9213-PB; uncharacterized protein, isoform B", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG9213)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;18327897;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q95RI4", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0071014 post-mRNA release spliceosomal complex", "go_biological_process": "GO:0000398 mRNA splicing, via spliceosome", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "Q9VXT5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VXY0-1", "uniprot_id": "CP4S3_DROME", "mass": 57189.0, "length": 495, "protein_name": "Probable cytochrome P450 4s3", "gene_name": "Cyp4s3", "organism": "Fruit fly", "refseq_name": "cytochrome P450 4s3", "refseq_ac": "NP_573003", "gene_names_uniprotkb": "Cyp4s3; CG9081", "gene_names_refseq": "4s3; CG9081; Cyp4s3; Dmel\\CG9081; RE63964", "protein_names_uniprotkb": "Probable cytochrome P450 4s3; 1.14.-.-; CYPIVS3", "protein_names_refseq": "CG9081-PA; Cyp4s3-PA; cytochrome P450 4s3; cytochrome P450", "tax_id": 7227, "disease": "Bietti crystalline corneoretinal dystrophy (Disease Ontology:DOID:0050664)", "pathway": " (dme:Dmel_CG9081); (R-DME-193144); (R-DME-196791); (R-DME-211916); (R-DME-211976)", "pathway_count": 5, "publication_count": 2, "publication_id_list": "10731132;12537572", "class_list": "", "function": "May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.14.-.-;1.14.15.-", "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0004497 monooxygenase activity;GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q9VXY0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VY20-1", "uniprot_id": "Q9VY20_DROME", "mass": 32861.0, "length": 285, "protein_name": "RING-type E3 ubiquitin transferase", "gene_name": "Dmel\\CG5347", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": "NP_572970", "gene_names_uniprotkb": "Dmel\\CG5347; CG5347; Dmel_CG5347", "gene_names_refseq": "CG5347; Dmel\\CG5347", "protein_names_uniprotkb": "RING-type E3 ubiquitin transferase; 2.3.2.27", "protein_names_refseq": "CG5347-PA; uncharacterized protein", "tax_id": 7227, "disease": "central precocious puberty 2 (Disease Ontology:DOID:0112309)", "pathway": " (dme:Dmel_CG5347)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding;GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity;GO:0004842 ubiquitin-protein transferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:1990904 ribonucleoprotein complex", "go_biological_process": "GO:0016567 protein ubiquitination;GO:0000209 protein polyubiquitination;GO:0060255 regulation of macromolecule metabolic process", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9VY20-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VYB0-1", "uniprot_id": "BTHD_DROME", "mass": 27774.0, "length": 249, "protein_name": "Selenoprotein BthD", "gene_name": "BthD", "organism": "Fruit fly", "refseq_name": "BthD selenoprotein", "refseq_ac": "NP_572903", "gene_names_uniprotkb": "BthD; CG11177", "gene_names_refseq": "BthD; CG11177; Dmel\\CG11177; SelH; dSelH; dselH; dselM", "protein_names_uniprotkb": "Selenoprotein BthD; dSelM", "protein_names_refseq": "BthD selenoprotein; BthD-PA; BthDselenoprotein; CG11177-PA", "tax_id": 7227, "disease": "colorectal adenoma (Disease Ontology:DOID:0050860); colorectal carcinoma (Disease Ontology:DOID:0080199)", "pathway": " (dme:Dmel_CG11177)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "10731132;11389138;11493597;12537569;12537572;14612395;17372656", "class_list": "", "function": "May be involved in a redox-related process. Required for survival and specifically for salivary gland morphogenesis., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q8MRZ5;Q962X5", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005576 extracellular region;GO:0005737 cytoplasm;GO:0005794 Golgi apparatus", "go_biological_process": "GO:0009792 embryo development ending in birth or egg hatching;GO:0051775 response to redox state;GO:0045454 cell redox homeostasis;GO:0008340 determination of adult lifespan;GO:0007432 salivary gland boundary specification", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q9VYB0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VYF8-1", "uniprot_id": "COQ5_DROME", "mass": 34338.0, "length": 301, "protein_name": "2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial", "gene_name": "Coq5", "organism": "Fruit fly", "refseq_name": "coenzyme Q5, isoform B", "refseq_ac": "NP_001285193", "gene_names_uniprotkb": "Coq5; CG2453; Dmel\\CG2453; Dmel_CG2453", "gene_names_refseq": "CG2453; Coq5; Dmel\\CG2453", "protein_names_uniprotkb": "2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; 2.1.1.201; Ubiquinone biosynthesis methyltransferase COQ5", "protein_names_refseq": "CG2453-PB; Coq5-PB; coenzyme Q5, isoform B", "tax_id": 7227, "disease": "coenzyme Q10 deficiency disease (Disease Ontology:DOID:0050730); primary coenzyme Q10 deficiency 9 (Disease Ontology:DOID:0112138)", "pathway": " (dme:Dmel_CG2453); (R-DME-2142789)", "pathway_count": 2, "publication_count": 12, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "Methyltransferase required for the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2)., [UniProtKB, HAMAP, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q8MR39", "ec_number_list": "2.1.1.-;2.1.1.114;2.1.1.64;1.14.15.45;1.14.15.46;4.1.1.130;2.1.1.201;1.14.99.60", "go_molecular_function": "GO:0008425 2-methoxy-6-polyprenyl-1,4-benzoquinol methyltransferase activity", "go_cellular_component": "GO:0031314 extrinsic component of mitochondrial inner membrane;GO:0005739 mitochondrion;GO:0110142 ubiquinone biosynthesis complex", "go_biological_process": "GO:0006744 ubiquinone biosynthetic process;GO:0032259 methylation", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "Q9VYF8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VYG2-1", "uniprot_id": "BAP60_DROME", "mass": 58170.0, "length": 515, "protein_name": "Brahma-associated protein of 60 kDa", "gene_name": "Bap60", "organism": "Fruit fly", "refseq_name": "brahma associated protein 60kD", "refseq_ac": "NP_511143", "gene_names_uniprotkb": "Bap60; CG4303", "gene_names_refseq": "BAF60; BAP60; BAPp60; Bap60; CG4303; Dmel\\CG4303; bap60; dBAP60; i127; i133", "protein_names_uniprotkb": "Brahma-associated protein of 60 kDa; BRM-associated protein 60", "protein_names_refseq": "BRM-associated protein 60; Bap60-PA; CG4303-PA; brahma associated protein 60 kDa; brahma associated protein 60 kD; brahma associated protein 60kD", "tax_id": 7227, "disease": "Coffin-Siris syndrome 11 (Disease Ontology:DOID:0112372); familial hyperlipidemia (Disease Ontology:DOID:1168); alcohol use disorder (Disease Ontology:DOID:1574); Coffin-Siris syndrome (Disease Ontology:DOID:1925)", "pathway": " (dme:Dmel_CG4303); (R-DME-3214858); (R-DME-400206); (R-DME-8939243); (R-DME-9707564); (R-DME-9933937); (R-DME-9933939); (R-DME-9933946); (R-DME-9933947); (R-DME-9934037)", "pathway_count": 10, "publication_count": 10, "publication_id_list": "10731132;10809665;12537569;12537572;15060132;16083904;20308539;24618901;25180232;9735357", "class_list": "", "function": "Involved in the recruitment and site-specific anchoring of the Brahma complex at specific promoter sites (PubMed:16083904, PubMed:24618901). The Brahma complex is a multiprotein complex which is the equivalent of the yeast SWI/SNF complex and acts by remodeling the chromatin by catalyzing an ATP-dependent alteration in the structure of nucleosomal DNA (PubMed:16083904, PubMed:24618901). This complex can both serve as a transcriptional coactivator or corepressor, depending on the context (PubMed:16083904). Participates in X-chromosomal dosage compensation (PubMed:16083904). Participates in neurogenesis (PubMed:16083904, PubMed:24618901)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 3, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "O76490", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0019904 protein domain specific binding;GO:0017022 myosin binding;GO:0003712 transcription coregulator activity;GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding", "go_cellular_component": "GO:0005634 nucleus;GO:0016514 SWI/SNF complex;GO:0000791 euchromatin;GO:0035060 brahma complex", "go_biological_process": "GO:0006338 chromatin remodeling;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0010628 positive regulation of gene expression;GO:0045893 positive regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "Q9VYG2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VYQ7-1", "uniprot_id": "CP311_DROME", "mass": 54790.0, "length": 483, "protein_name": "Probable cytochrome P450 311a1", "gene_name": "Cyp311a1", "organism": "Fruit fly", "refseq_name": "cytochrome P450 311a1", "refseq_ac": "NP_572780", "gene_names_uniprotkb": "Cyp311a1; CG1488", "gene_names_refseq": "311a1; CG1488; CYP311A1; Cyp311a1; Dmel\\CG1488", "protein_names_uniprotkb": "Probable cytochrome P450 311a1; 1.14.-.-; CYPCCCXIA1", "protein_names_refseq": "CG1488-PB; Cyp311a1-PB; cytochrome P450 311a1; cytochrome P450", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG1488); (R-DME-211935); (R-DME-211958); (R-DME-211979); (R-DME-2142691); (R-DME-2142816)", "pathway_count": 6, "publication_count": 3, "publication_id_list": "10731132;12537569;12537572", "class_list": "", "function": "May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q8SX16", "ec_number_list": "1.14.-.-;1.14.14.-;1.14.15.-", "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0004497 monooxygenase activity;GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9VYQ7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VYS4-1", "uniprot_id": "GLD2B_DROME", "mass": 151312.0, "length": 1373, "protein_name": "Poly(A) RNA polymerase gld-2 homolog B", "gene_name": "wisp", "organism": "Fruit fly", "refseq_name": "wispy, isoform C", "refseq_ac": "NP_001285144", "gene_names_uniprotkb": "wisp; CG15737; DmCG15737; Dmel\\CG15737; Dmel_CG15737; PAP; TAMP; TUTase2; Wispy; Wisp; fs(1)M19", "gene_names_refseq": "CG15737; DmCG15737; Dmel\\CG15737; PAP; TAMP; TUTase2; Wispy; Wisp; fs(1)M19; wisp", "protein_names_uniprotkb": "Poly(A) RNA polymerase gld-2 homolog B; 2.7.7.19; Protein wispy", "protein_names_refseq": "3' terminal uridylyl transferase 2; CG15737-PC; female sterile(1)M19; poly(A) polymerase; temprano; toll pathway activation mediating protein; wisp-PC; wispy, isoform C; wispy", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG15737)", "pathway_count": 1, "publication_count": 16, "publication_id_list": "10731132;10747060;12537568;12537572;12537573;12537574;12871909;16110336;17569856;17569867;18430932;18434412;25589440;26109356;26109357;29317541", "class_list": "", "function": "Cytoplasmic poly(A) RNA polymerase that adds successive AMP monomers to the 3'-end of specific maternal RNAs (bcd, Tl, and tor), forming a poly(A) tail, during late oogenesis and early embryogenesis (PubMed:18430932, PubMed:18434412, PubMed:29317541). In contrast to the canonical nuclear poly(A) RNA polymerase, it only adds poly(A) to selected cytoplasmic mRNAs (PubMed:18430932, PubMed:18434412). Required for localization of mRNAs to both poles of the egg, to recruit or maintain known centrosomal proteins with two types of microtubule organizing centers (MTOCs): the central MTOC that forms between the meiosis II tandem spindles and the centrosomes of the mitotic spindle (PubMed:10747060). Required at the final stage of oogenesis for meiosis I metaphase arrest and for progression beyond this stage (PubMed:10747060, PubMed:12871909, PubMed:18434412). Functions with the RNA-binding protein Dcr-2 to promote cytoplasmic polyadenylation and translational activation of certain mRNAs such as Tl and r2d2 (PubMed:29317541). As a consequence, is involved in regulating Toll immune signaling and promoting resistance to fungal infection (PubMed:29317541)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.7.19", "go_molecular_function": "GO:0003723 RNA binding;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:1990817 poly(A) RNA polymerase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0001556 oocyte maturation;GO:0048477 oogenesis;GO:0007052 mitotic spindle organization;GO:0008298 intracellular mRNA localization;GO:0007344 pronuclear fusion", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "Q9VYS4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VYV5-1", "uniprot_id": "FUT8_DROME", "mass": 70206.0, "length": 619, "protein_name": "Alpha-(1,6)-fucosyltransferase", "gene_name": "FucT6", "organism": "Fruit fly", "refseq_name": "alpha1,6-fucosyltransferase", "refseq_ac": "NP_572740", "gene_names_uniprotkb": "FucT6; CG2448", "gene_names_refseq": "6-FucT; BEST:CK00490; CG2448; CK00490; Dm alpha1; Dmel\\CG2448; Fuc-TVIII; FucT6; dalpha6Fut", "protein_names_uniprotkb": "Alpha-(1,6)-fucosyltransferase; 2.4.1.68; Alpha1-6FucT; GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase; GDP-fucose--glycoprotein fucosyltransferase; Glycoprotein 6-alpha-L-fucosyltransferase", "protein_names_refseq": "CG2448-PA; FucT6-PA; alpha1,6-fucosyltransferase; core alpha1,6-fucosyltransferase", "tax_id": 7227, "disease": "pulmonary emphysema (Disease Ontology:DOID:9675)", "pathway": " (dme:Dmel_CG2448); (R-DME-975578)", "pathway_count": 2, "publication_count": 5, "publication_id_list": "10731132;11698403;12537569;12537572;15604090", "class_list": "", "function": "Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans. The addition is prevented if the GlcNAc residue is already alpha1,3-fucosylated., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.4.1.68", "go_molecular_function": "GO:0046921 alpha-(1->6)-fucosyltransferase activity;GO:0046872 metal ion binding;GO:0008424 glycoprotein 6-alpha-L-fucosyltransferase activity", "go_cellular_component": "GO:0032580 Golgi cisterna membrane", "go_biological_process": "GO:0006487 protein N-linked glycosylation;GO:0046368 GDP-L-fucose metabolic process;GO:0016258 Golgi apparatus N-glycan diversification", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q9VYV5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VYY4-1", "uniprot_id": "C4G15_DROME", "mass": 65380.0, "length": 574, "protein_name": "Cytochrome P450 4g15", "gene_name": "Cyp4g15", "organism": "Fruit fly", "refseq_name": "cytochrome P450 4g15, isoform A", "refseq_ac": "NP_572721", "gene_names_uniprotkb": "Cyp4g15; CG11715", "gene_names_refseq": "152658_at; 4g15; CG11715; CYP4G15; Cyp4g15; Dmel\\CG11715; cyp4g15", "protein_names_uniprotkb": "Cytochrome P450 4g15; 1.14.-.-; CYPIVG15", "protein_names_refseq": "CG11715-PA; Cyp4g15-PA; cytochrome P450 4g15, isoform A; cytochrome P450", "tax_id": 7227, "disease": "Bietti crystalline corneoretinal dystrophy (Disease Ontology:DOID:0050664)", "pathway": " (dme:Dmel_CG11715); (R-DME-193144); (R-DME-196791); (R-DME-211916); (R-DME-211976)", "pathway_count": 5, "publication_count": 5, "publication_id_list": "10731132;10891384;12537569;12537572;38008364", "class_list": "", "function": "Oxidative decarbonylase catalyzing the terminal step in insect hydrocarbon production (PubMed:38008364). Probably involved in steroid hormone biosynthesis., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q8IR88", "ec_number_list": "1.14.-.-;1.14.15.-", "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0004497 monooxygenase activity;GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q9VYY4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VYY9-1", "uniprot_id": "EVI5_DROME", "mass": 92782.0, "length": 807, "protein_name": "Ecotropic viral integration site 5 ortholog", "gene_name": "Evi5", "organism": "Fruit fly", "refseq_name": "ecotropic viral integration site 5, isoform C", "refseq_ac": "NP_001162721", "gene_names_uniprotkb": "Evi5; CG11727", "gene_names_refseq": "BcDNA:GH08923; BcDNA:LD11130; CG11727; Dmel\\CG11727; Evi5; MRE21", "protein_names_uniprotkb": "Ecotropic viral integration site 5 ortholog", "protein_names_refseq": "CG11727-PC; Evi5-PC; ecotropic viral integration site 5 ortholog; ecotropic viral integration site 5, isoform C; mRNA-like ncRNA in embryogenesis 21", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG11727)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "10731132;12537569;12537572;17372656;18327897;22778279", "class_list": "", "function": "Functions as a GTPase-activating protein (GAP). During border cell migration in the ovary, acts as a GAP for Rab11 and is necessary for the maintenance of active receptor tyrosine kinases at the leading edge., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "C9QP48;E1JJH7;F0JAJ2;Q8IR89;Q8MT90;Q95S00", "ec_number_list": "", "go_molecular_function": "GO:0005096 GTPase activator activity;GO:0031267 small GTPase binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005768 endosome;GO:0005794 Golgi apparatus;GO:0031982 vesicle", "go_biological_process": "GO:0032880 regulation of protein localization;GO:0030334 regulation of cell migration", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q9VYY9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VYZ2-1", "uniprot_id": "GR10B_DROME", "mass": 44030.0, "length": 373, "protein_name": "Putative gustatory receptor 10b", "gene_name": "Gr10b", "organism": "Fruit fly", "refseq_name": "gustatory receptor 10b", "refseq_ac": "NP_511121", "gene_names_uniprotkb": "Gr10b; CG12622", "gene_names_refseq": "CG12622; Dmel\\CG12622; GR10b; Gr10B2; Gr10b", "protein_names_uniprotkb": "Putative gustatory receptor 10b", "protein_names_refseq": "CG12622-PA; Gr10b-PA; gustatory receptor 10B2; gustatory receptor 10b", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG12622)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "10731132;12537572", "class_list": "", "function": "Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0015276 ligand-gated monoatomic ion channel activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0030424 axon;GO:0030425 dendrite;GO:0043025 neuronal cell body", "go_biological_process": "GO:0008049 male courtship behavior;GO:0007165 signal transduction;GO:0034220 monoatomic ion transmembrane transport;GO:0007635 chemosensory behavior;GO:0050909 sensory perception of taste", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q9VYZ2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VZ49-1", "uniprot_id": "ENDUA_DROME", "mass": 63596.0, "length": 592, "protein_name": "Endoribonuclease Arlr", "gene_name": "Arlr", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform B", "refseq_ac": "NP_001285102", "gene_names_uniprotkb": "Arlr; CG2145", "gene_names_refseq": "CG2145; Dmel\\CG2145; Dmel_CG2145", "protein_names_uniprotkb": "Endoribonuclease Arlr; 3.1.-.-; 4.6.1.-; Poly(U)-specific endoribonuclease homolog; Protein Age-related lipid regulator", "protein_names_refseq": "CG2145-PB; uncharacterized protein, isoform B", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG2145)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "10731132;12537569;12537572;28139767;37803019", "class_list": "", "function": "Endoribonuclease that cleaves single-stranded RNAs; unlike its paralog EndoU it does not appear to preferentially cleave at uridylates and releases linear products instead of products that have 2'-3'-cyclic phosphate termini (PubMed:28139767). Preferentially cleaves single stranded RNA at sites with AU, UC and poly-U sites cleaved less efficiently (PubMed:28139767). Targets mRNAs encoding proteins involved in lipid metabolism, particularly those involved in lipolysis, to regulate their expression (PubMed:37803019)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 9, "predicted_n_glycosites": 0, "predicted_o_glycosites": 9, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 9, "binding_glycan_count": 0, "secondary_ac_list": "A9UNF0;Q8SY54;X2JJD6", "ec_number_list": "3.1.-.-;4.6.1.-", "go_molecular_function": "GO:0003723 RNA binding;GO:0016787 hydrolase activity;GO:0046872 metal ion binding;GO:0004521 RNA endonuclease activity;GO:0033897 ribonuclease T2 activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0005783 endoplasmic reticulum;GO:0005788 endoplasmic reticulum lumen", "go_biological_process": "GO:0050995 negative regulation of lipid catabolic process;GO:0061157 mRNA destabilization;GO:0016441 post-transcriptional gene silencing", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q9VZ49-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VZ64-1", "uniprot_id": "6PGL_DROME", "mass": 26672.0, "length": 243, "protein_name": "Probable 6-phosphogluconolactonase", "gene_name": "Pgls", "organism": "Fruit fly", "refseq_name": "6-phosphogluconolactonase", "refseq_ac": "NP_572656", "gene_names_uniprotkb": "Pgls; CG17333", "gene_names_refseq": "6PGL; CG17333; Dm6PGL; Dmel\\CG17333; PGLS; Pgls", "protein_names_uniprotkb": "Probable 6-phosphogluconolactonase; 3.1.1.31; 6PGL", "protein_names_refseq": "6-phosphogluconolactonase; CG17333-PA; Pgls-PA", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG17333); (R-DME-71336)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "10731132;12537572", "class_list": "", "function": "Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q53XD9", "ec_number_list": "3.1.1.31", "go_molecular_function": "GO:0017057 6-phosphogluconolactonase activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0005975 carbohydrate metabolic process;GO:0009051 pentose-phosphate shunt, oxidative branch", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q9VZ64-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VZD2-1", "uniprot_id": "BN3D3_DROME", "mass": 28070.0, "length": 238, "protein_name": "Probable RNA methyltransferase CG11342", "gene_name": "CG11342", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": "NP_647896", "gene_names_uniprotkb": "CG11342", "gene_names_refseq": "CG11342; Dmel\\CG11342", "protein_names_uniprotkb": "Probable RNA methyltransferase CG11342; 2.1.1.-", "protein_names_refseq": "CG11342-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG11342)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "10731132;12537572", "class_list": "", "function": "Probable RNA methyltransferase., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008171 O-methyltransferase activity;GO:0008173 RNA methyltransferase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0032259 methylation;GO:2000632 negative regulation of pre-miRNA processing", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q9VZD2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VZE6-1", "uniprot_id": "BRX1_DROME", "mass": 41618.0, "length": 359, "protein_name": "Ribosome biogenesis protein BRX1 homolog", "gene_name": "CG11583", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": "NP_001033989", "gene_names_uniprotkb": "CG11583", "gene_names_refseq": "CG11583; CG32253; Dmel\\CG11583; dBRX1", "protein_names_uniprotkb": "Ribosome biogenesis protein BRX1 homolog; Brix domain-containing protein 2 homolog", "protein_names_refseq": "CG11583-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG11583)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "10731132;12537569;12537572", "class_list": "", "function": "Required for biogenesis of the 60S ribosomal subunit., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q8MSC3", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding;GO:0019843 rRNA binding", "go_cellular_component": "GO:0005730 nucleolus", "go_biological_process": "GO:0006364 rRNA processing;GO:0000027 ribosomal large subunit assembly", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9VZE6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VZH1-1", "uniprot_id": "CF298_DROME", "mass": 33117.0, "length": 291, "protein_name": "Cilia- and flagella-associated protein 298", "gene_name": "CG18675", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": "NP_652334", "gene_names_uniprotkb": "CG18675", "gene_names_refseq": "CG18675; Dmel\\CG18675", "protein_names_uniprotkb": "Cilia- and flagella-associated protein 298", "protein_names_refseq": "CG18675-PA; uncharacterized protein", "tax_id": 7227, "disease": "primary ciliary dyskinesia 26 (Disease Ontology:DOID:0110627)", "pathway": " (dme:Dmel_CG18675)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "10731132;12537569;12537572", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q8T478", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "GO:0003352 regulation of cilium movement", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9VZH1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VZH2-1", "uniprot_id": "MAS_DROME", "mass": 111564.0, "length": 1047, "protein_name": "Protein masquerade", "gene_name": "mas", "organism": "Fruit fly", "refseq_name": "masquerade, isoform C", "refseq_ac": "NP_001261408", "gene_names_uniprotkb": "mas; CG15002; SPH79; c-SPH79", "gene_names_refseq": "CG15002; Dmel\\CG15002; Mas; SPH79; c-SPH79; cSPH79; mas", "protein_names_uniprotkb": "Protein masquerade", "protein_names_refseq": "CG15002-PC; mas-PC; masquerade, isoform C; masquerade", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG15002)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "10731132;11441068;12537569;12537572;7851790;8817456", "class_list": "", "function": "In embryogenesis, has a role in somatic muscle attachment and in the development of axonal pathways probably by stabilizing cell-matrix adhesion and/or by acting as a competitive antagonist of serine proteases., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 9, "predicted_n_glycosites": 6, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 9, "binding_glycan_count": 0, "secondary_ac_list": "M9PE44;Q24019;Q960I5", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005615 extracellular space;GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0030424 axon;GO:0043025 neuronal cell body", "go_biological_process": "GO:0006508 proteolysis;GO:0010976 positive regulation of neuron projection development;GO:0007417 central nervous system development;GO:0007422 peripheral nervous system development;GO:0061564 axon development", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q9VZH2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VZI2-1", "uniprot_id": "ACK_DROME", "mass": 118418.0, "length": 1073, "protein_name": "Activated Cdc42 kinase Ack", "gene_name": "Ack", "organism": "Fruit fly", "refseq_name": "activated Cdc42 kinase", "refseq_ac": "NP_647859", "gene_names_uniprotkb": "Ack; CG14992; DACK; p145", "gene_names_refseq": "ACK2; ACK; Ack; BcDNA:GH10777; CG14992; DACK; DAck; Dmel\\CG14992; dACK; p145", "protein_names_uniprotkb": "Activated Cdc42 kinase Ack; 2.7.10.2; 2.7.11.1", "protein_names_refseq": "Ack-PA; CG14992-PA; activated Cdc42 kinase", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG14992)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "10731132;11773052;11997505;12537569;12537572;18816840;22615583;23562806;23579691;25223282;27462444;40245499", "class_list": "", "function": "Non-receptor tyrosine-protein and serine/threonine-protein kinase that is implicated in diverse biological functions such as cell survival, cell differentiation, cell growth and proliferation (PubMed:11997505, PubMed:18816840, PubMed:22615583, PubMed:23562806, PubMed:25223282, PubMed:27462444). Phosphorylates SH3PX1 and ex (PubMed:11773052, PubMed:22615583, PubMed:27462444). Phosphorylates SH3PX1 predominantly on 'Tyr-56', which likely promotes the recruitment of SH3PX1 to an axonal guidance receptor complex that includes dock and Dscam; because phosphorylation of SH3PX1 increases its interaction with the complex member dock while decreasing its interaction with the actin cytoskeleton modulator WASp (PubMed:11773052). In the wing and eye, promotes tissue growth, and during embryogenesis coordinates cell shape changes required for correct dorsal closure (PubMed:18816840, PubMed:22615583, PubMed:27462444). Functions in the negative regulation of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway by enhancing yki activity thereby promoting cell proliferation and inhibiting apoptosis (PubMed:22615583, PubMed:27462444). This is accomplished, at least in part, by phosphorylating ex thereby reducing its ability to efficiently activate the Hippo signaling cascade (PubMed:27462444). In the eye disk, wing disk and possibly spermatids, inhibits programmed cell death induced by hid and rpr through a mechanism that is independent of the MAP kinase signal transduction pathway (PubMed:22615583). Essential for male and female fertility (PubMed:22615583, PubMed:23562806). During oogenesis required for the correct temporal assembly, and consequently the catalytic activity of long Ctps filaments (cytoophidium) in the germline nurse cells, likely by phosphorylating an unidentified substrate that is essential for linking individual Ctps filaments into large, catalytically active assemblies (PubMed:25223282)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 3, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q9U4G3", "ec_number_list": "2.7.11.17;2.7.11.1;2.7.11.13;2.7.11.24;2.7.10.1;2.7.11.22;2.7.11.21;2.7.10.2;5.6.1.8;2.7.11.11;2.7.11.23;2.7.12.1;2.7.11.25;2.7.11.12;2.7.12.2;2.7.11.39", "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0004713 protein tyrosine kinase activity;GO:0004715 non-membrane spanning protein tyrosine kinase activity;GO:0005524 ATP binding;GO:0017124 SH3 domain binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0030136 clathrin-coated vesicle;GO:0071944 cell periphery;GO:0032991 protein-containing complex", "go_biological_process": "GO:0031034 myosin filament assembly;GO:0043066 negative regulation of apoptotic process;GO:0007286 spermatid development;GO:0008104 intracellular protein localization;GO:0035331 negative regulation of hippo signaling", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "Q9VZI2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VZJ6-1", "uniprot_id": "GR64D_DROME", "mass": 48869.0, "length": 417, "protein_name": "Gustatory receptor for sugar taste 64d", "gene_name": "Gr64d", "organism": "Fruit fly", "refseq_name": "gustatory receptor 64d, isoform C", "refseq_ac": "NP_001027105", "gene_names_uniprotkb": "Gr64d; CG14987", "gene_names_refseq": "CG14987; CG33157; Dmel64d; Dmel\\CG14987; GR64d; Gr64d; Gr64", "protein_names_uniprotkb": "Gustatory receptor for sugar taste 64d", "protein_names_refseq": "CG14987-PC; Gr64d-PC; gustatory receptor 64d, isoform C", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG14987)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "10731132;11516643;12537572;14608037;17715294;23850280", "class_list": "", "function": "One of the few identified sugar gustatory receptors identified so far and which promotes the starvation-induced increase of feeding motivation., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 1, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0015276 ligand-gated monoatomic ion channel activity;GO:0033041 sweet taste receptor activity;GO:0008527 taste receptor activity;GO:0170021 ionotropic taste receptor activity;GO:0170023 ionotropic sweet taste receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane", "go_biological_process": "GO:0007165 signal transduction;GO:0034220 monoatomic ion transmembrane transport;GO:0050912 detection of chemical stimulus involved in sensory perception of taste;GO:0050916 sensory perception of sweet taste;GO:0007637 proboscis extension reflex", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q9VZJ6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VZJ9-1", "uniprot_id": "MUL1_DROME", "mass": 37844.0, "length": 338, "protein_name": "Mitochondrial E3 ubiquitin protein ligase 1", "gene_name": "Mul1", "organism": "Fruit fly", "refseq_name": "mitochondrial E3 ubiquitin protein ligase 1, isoform B", "refseq_ac": "NP_001303365", "gene_names_uniprotkb": "Mul1; CG1134", "gene_names_refseq": "CG1134; Dmel\\CG1134; MUL1; Mul1; mul1", "protein_names_uniprotkb": "Mitochondrial E3 ubiquitin protein ligase 1; 2.3.2.27; Mitochondrial E3 ubiquitin protein transferase 1", "protein_names_refseq": "CG1134-PB; Mul1-PB; mitochondrial E3 ubiquitin protein ligase 1 homologue; mitochondrial E3 ubiquitin protein ligase 1, isoform B", "tax_id": 7227, "disease": "Parkinson's disease (Disease Ontology:DOID:14330)", "pathway": " (dme:Dmel_CG1134); (R-DME-5689880); (R-DME-8951664); (R-DME-9755511)", "pathway_count": 4, "publication_count": 4, "publication_id_list": "10731132;12537569;12537572;24898855", "class_list": "", "function": "Exhibits weak E3 ubiquitin-protein ligase activity. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. Plays a role in the control of mitochondrial morphology by promoting mitochondrial fission. Negatively regulates the mitochondrial fusion protein marf by promoting its ubiquitination, acting in a pathway that is parallel to the park/pink1 regulatory pathway., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.1.1.29;3.4.24.56;3.6.5.-;3.4.19.12;2.3.2.27", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005741 mitochondrial outer membrane;GO:0005777 peroxisome", "go_biological_process": "GO:0050821 protein stabilization;GO:0016567 protein ubiquitination;GO:0090141 positive regulation of mitochondrial fission", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q9VZJ9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VZM7-1", "uniprot_id": "INT10_DROME", "mass": 72257.0, "length": 631, "protein_name": "Integrator complex subunit 10", "gene_name": "IntS10", "organism": "Fruit fly", "refseq_name": "integrator 10", "refseq_ac": "NP_647830", "gene_names_uniprotkb": "IntS10; CG1120", "gene_names_refseq": "CG1120; Dmel\\CG1120; Int10; IntS10", "protein_names_uniprotkb": "Integrator complex subunit 10", "protein_names_refseq": "CG1120-PA; IntS10-PA; integrator 10", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG1120); (R-DME-6807505)", "pathway_count": 2, "publication_count": 8, "publication_id_list": "10731132;12537572;21078872;23097424;31530651;32966759;37995689;39032490", "class_list": "", "function": "Component of the integrator complex, a multiprotein complex that terminates RNA polymerase II (Pol II) transcription in the promoter-proximal region of genes (PubMed:21078872, PubMed:23097424, PubMed:32966759). The integrator complex provides a quality checkpoint during transcription elongation by driving premature transcription termination of transcripts that are unfavorably configured for transcriptional elongation: the complex terminates transcription by (1) catalyzing dephosphorylation of the C-terminal domain (CTD) of Pol II subunit Polr2A/Rbp1 and Spt5, and (2) degrading the exiting nascent RNA transcript via endonuclease activity (PubMed:32966759). The integrator complex is also involved in the 3'-end processing of the U7 snRNA, and also the spliceosomal snRNAs U1, U2, U4 and U5 (PubMed:21078872, PubMed:23097424)., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0032039 integrator complex;GO:0160232 INTAC complex", "go_biological_process": "GO:0016180 snRNA processing;GO:0160240 RNA polymerase II transcription initiation surveillance", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q9VZM7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VZS3-1", "uniprot_id": "ETIF1_DROME", "mass": 12450.0, "length": 110, "protein_name": "Eukaryotic translation initiation factor eIF1", "gene_name": "eIF1", "organism": "Fruit fly", "refseq_name": "eukaryotic translation initiation factor 1", "refseq_ac": "NP_647792", "gene_names_uniprotkb": "eIF1; CG17737", "gene_names_refseq": "BcDNA:RE14985; CG17737; Dmel\\CG17737; EIF1; anon-EST:Posey272; dEIF1; eIF1", "protein_names_uniprotkb": "Eukaryotic translation initiation factor eIF1; Protein translation factor SUI1 homolog", "protein_names_refseq": "CG17737-PA; eIF1-PA; eukaryotic translation initiation factor 1", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG17737)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "10731132;12537569;12537572;17372656", "class_list": "", "function": "Probably involved in translation., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding;GO:0043024 ribosomal small subunit binding;GO:0003743 translation initiation factor activity", "go_cellular_component": "GO:0016282 eukaryotic 43S preinitiation complex;GO:0043614 multi-eIF complex", "go_biological_process": "GO:0006417 regulation of translation;GO:0071456 cellular response to hypoxia;GO:0001731 formation of translation preinitiation complex", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q9VZS3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VZU2-1", "uniprot_id": "HHAT_DROME", "mass": 58106.0, "length": 500, "protein_name": "Protein-cysteine N-palmitoyltransferase Rasp", "gene_name": "rasp", "organism": "Fruit fly", "refseq_name": "rasp", "refseq_ac": "NP_523898", "gene_names_uniprotkb": "rasp; CG11495; cmn; sit; ski", "gene_names_refseq": "7F21; CG11495; Dmel\\CG11495; RASP; Rasp; Ski; cmn; cnm; l(3)63Bg; l(3)M47; l(3)SG3; l(3)m47; rasp; rsp; sig/ski; sit; ski/sit; ski", "protein_names_uniprotkb": "Protein-cysteine N-palmitoyltransferase Rasp; 2.3.1.-; Protein central missing; Protein sightless; Protein skinny hedgehog", "protein_names_refseq": "CG11495-PA; central missing; lethal(3)63Bg; lethal(3)SG3; rasp-PA; rasp; sightless; skinny hedgehog", "tax_id": 7227, "disease": "chondrodysplasia-pseudohermaphroditism syndrome (Disease Ontology:DOID:0060644)", "pathway": " (dme:Dmel_CG11495); (R-DME-209471); (R-DME-5358346)", "pathway_count": 3, "publication_count": 16, "publication_id_list": "10549295;10619433;10731132;11395778;11486055;11509241;11748147;11861468;12537569;12537572;14729575;15189162;15563523;15875013;18198278;8824192", "class_list": "", "function": "Required in hedgehog (hh) expressing cells for production of appropriate signaling activity in embryos and in the imaginal precursors of adult tissues. Acts within the secretory pathway to catalyze N-terminal palmitoylation of Hh; this lipid modification is required for the embryonic and larval patterning activities of the Hh signal. Not required for Wg signaling., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q95VY0", "ec_number_list": "3.1.-.-;2.3.1.-", "go_molecular_function": "GO:0019706 protein-cysteine S-palmitoyltransferase activity;GO:0016746 acyltransferase activity;GO:0016409 palmitoyltransferase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005829 cytosol;GO:0016020 membrane", "go_biological_process": "GO:0007224 smoothened signaling pathway;GO:0007225 patched ligand maturation;GO:0018009 N-terminal peptidyl-L-cysteine N-palmitoylation;GO:0038004 epidermal growth factor receptor ligand maturation;GO:0007367 segment polarity determination", "synthesized_glycan_count": 0, "hit_score": 1.7, "record_id": "Q9VZU2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VZV5-1", "uniprot_id": "CYHR1_DROME", "mass": 45395.0, "length": 412, "protein_name": "Zinc finger TRAF-type-containing protein 1 homolog", "gene_name": "CG32486", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": "NP_647765", "gene_names_uniprotkb": "CG32486", "gene_names_refseq": "CG14954; CG16745; CG32486; Dmel\\CG32486; anon-WO0118547.267; l(2)SH3 095; l(3)SH095", "protein_names_uniprotkb": "Zinc finger TRAF-type-containing protein 1 homolog; Cysteine and histidine-rich protein 1 homolog", "protein_names_refseq": "CG32486-PD; lethal (3) SH095; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG32486)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "10731132;12537569;12537572", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q960J5", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9VZV5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9VZZ9-1", "uniprot_id": "DOS_DROME", "mass": 95536.0, "length": 878, "protein_name": "Protein daughter of sevenless", "gene_name": "dos", "organism": "Fruit fly", "refseq_name": "daughter of sevenless, isoform A", "refseq_ac": "NP_523890", "gene_names_uniprotkb": "dos; CG1044", "gene_names_refseq": "141511_at; CG1044; DOS; Dmel\\CG1044; Dos; E(csw)3A; E(csw[CS])3A; EC3-4; Gab-1; Su(sev)3A; Su(sev[S11])3A; dos", "protein_names_uniprotkb": "Protein daughter of sevenless", "protein_names_refseq": "CG1044-PA; daughter of sevenless, isoform A; daughter of sevenless; dos-PA; enhancer of corkscrew-CS; suppressor of sevenless-S11", "tax_id": 7227, "disease": "autosomal recessive nonsyndromic deafness 26 (Disease Ontology:DOID:0110484); chronic myeloid leukemia (Disease Ontology:DOID:8552)", "pathway": " (dme:Dmel_CG1044); (R-DME-109704); (R-DME-1257604); (R-DME-180292); (R-DME-1963642); (R-DME-2730905); (R-DME-5654689); (R-DME-5654695); (R-DME-5654710); (R-DME-5654720); (R-DME-6811558); (R-DME-8853659)", "pathway_count": 12, "publication_count": 10, "publication_id_list": "10601017;10640704;10731132;12128212;12537569;12537572;17372656;18327897;8681384;8681385", "class_list": "", "function": "Essential component for signaling from various receptor tyrosine kinases such as Sevenless, TORSO and DER. Required for photoreceptor cell and wing development., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 4, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q24452;Q9W000", "ec_number_list": "", "go_molecular_function": "GO:0042169 SH2 domain binding;GO:0035591 signaling adaptor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane", "go_biological_process": "GO:0007165 signal transduction;GO:0042461 photoreceptor cell development;GO:0046578 regulation of Ras protein signal transduction;GO:0008595 anterior/posterior axis specification, embryo;GO:0007465 R7 cell fate commitment", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "Q9VZZ9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9W011-1", "uniprot_id": "C4D20_DROME", "mass": 58213.0, "length": 510, "protein_name": "Probable cytochrome P450 4d20", "gene_name": "Cyp4d20", "organism": "Fruit fly", "refseq_name": "cytochrome P450 4d20", "refseq_ac": "NP_647723", "gene_names_uniprotkb": "Cyp4d20; CG16761", "gene_names_refseq": "4d20; CG16761; CYP4d20; Cyp4d20; Dmel\\CG16761; RH59895", "protein_names_uniprotkb": "Probable cytochrome P450 4d20; 1.14.-.-; CYPIVD20", "protein_names_refseq": "CG16761-PA; Cyp4d20-PA; cytochrome P450 4d20", "tax_id": 7227, "disease": "Bietti crystalline corneoretinal dystrophy (Disease Ontology:DOID:0050664); autosomal recessive polycystic kidney disease (Disease Ontology:DOID:0110861)", "pathway": " (dme:Dmel_CG16761); (R-DME-193144); (R-DME-196791); (R-DME-211916); (R-DME-211976)", "pathway_count": 5, "publication_count": 2, "publication_id_list": "10731132;12537572", "class_list": "", "function": "May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.14.-.-;1.14.15.-", "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0004497 monooxygenase activity;GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q9W011-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9W056-1", "uniprot_id": "S36A_DROME", "mass": 50042.0, "length": 451, "protein_name": "Proton-coupled amino acid transporter-like protein acs", "gene_name": "acs", "organism": "Fruit fly", "refseq_name": "arcus", "refseq_ac": "NP_647686", "gene_names_uniprotkb": "acs; CG1139", "gene_names_refseq": "CG1139; Dmel\\CG1139; acs", "protein_names_uniprotkb": "Proton-coupled amino acid transporter-like protein acs; Protein arcus", "protein_names_refseq": "CG1139-PA; acs-PA; arcus", "tax_id": 7227, "disease": "iminoglycinuria (Disease Ontology:DOID:0112265)", "pathway": " (dme:Dmel_CG1139); (R-DME-352230); (R-DME-428559); (R-DME-71240)", "pathway_count": 4, "publication_count": 6, "publication_id_list": "10731132;12537569;12537572;15843412;22574197;37636057", "class_list": "", "function": "Amino acid transporter which has pH-dependent electrogenic transport activity for alanine, glycine and proline (PubMed:15843412). Plays a role in positive regulation of growth by directly or indirectly modulating the effects of the TOR signaling pathway (PubMed:15843412, PubMed:22574197). Required in enterocytes for the efficient recovery of gut epithelium following the cytoplasmic purge response to bacterial infection (PubMed:37636057). Acts cell-autonomously to promote the retrograde transport of amino acids into the intestinal epithelium (PubMed:37636057). Acts non-cell-autonomously through the insulin signaling pathway to stimulate Myc expression and the release of amino acids from nutrient stores into the hemolymph (PubMed:37636057)., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0015179 L-amino acid transmembrane transporter activity;GO:0015171 amino acid transmembrane transporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005765 lysosomal membrane;GO:0031902 late endosome membrane;GO:0005774 vacuolar membrane;GO:0031090 organelle membrane", "go_biological_process": "GO:0040008 regulation of growth;GO:0003333 amino acid transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q9W056-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9W088-1", "uniprot_id": "DPOD2_DROME", "mass": 48009.0, "length": 431, "protein_name": "DNA polymerase delta subunit 2", "gene_name": "PolD2", "organism": "Fruit fly", "refseq_name": "DNA polymerase delta subunit 2", "refseq_ac": "NP_647659", "gene_names_uniprotkb": "PolD2; CG12018; DNApolD1; Pol31", "gene_names_refseq": "12018; BcDNA:HL03874; CG12018; Dmel\\CG12018; Pol31; PolD2", "protein_names_uniprotkb": "DNA polymerase delta subunit 2; Pol31 polymerase delta subunit", "protein_names_refseq": "CG12018-PA; DNA polymerase delta small subunit; DNA polymerase delta subunit 2; DNApol- delta small subunit; Pol31 polymerase delta subunit; PolD2-PA", "tax_id": 7227, "disease": "cancer (Disease Ontology:DOID:162)", "pathway": " (dme:Dmel_CG12018); (R-DME-69166); (R-DME-69183)", "pathway_count": 3, "publication_count": 4, "publication_id_list": "10731132;12537569;12537572;31100062", "class_list": "", "function": "Accessory component of both the DNA polymerase delta complex and possibly the DNA polymerase zeta complex (By similarity). As a component of the delta complex, participates in high fidelity genome replication, including lagging strand synthesis, DNA recombination and repair (By similarity). Appears to promote the function of the DNA pol-delta complex accessory subunit PolD3 in both embryonic and postembryonic somatic cells (PubMed:31100062)., [UniProtKB, UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q8MZ80;Q9U9Q3;T2GGB6", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding", "go_cellular_component": "GO:0043625 delta DNA polymerase complex;GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0016035 zeta DNA polymerase complex", "go_biological_process": "GO:0006271 DNA strand elongation involved in DNA replication;GO:0042276 error-prone translesion synthesis;GO:0006261 DNA-templated DNA replication;GO:1990506 mitotic DNA-templated DNA replication", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q9W088-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9W092-1", "uniprot_id": "CHIT2_DROME", "mass": 54122.0, "length": 484, "protein_name": "Probable chitinase 2", "gene_name": "Cht2", "organism": "Fruit fly", "refseq_name": "chitinase 2, isoform B", "refseq_ac": "NP_001246550", "gene_names_uniprotkb": "Cht2; CG2054", "gene_names_refseq": "CG2054; CHT2; Cht-2; Cht2; Cht; DmCHT2; DmCht2; Dmel\\CG2054; cht2", "protein_names_uniprotkb": "Probable chitinase 2; 3.2.1.14", "protein_names_refseq": "CG2054-PB; Cht2-PB; chitinase 2, isoform B", "tax_id": 7227, "disease": "invasive aspergillosis (Disease Ontology:DOID:0050073); sinusitis (Disease Ontology:DOID:0050127); silicosis (Disease Ontology:DOID:10325); cryptococcosis (Disease Ontology:DOID:12053); relapsing-remitting multiple sclerosis (Disease Ontology:DOID:2378); asthma (Disease Ontology:DOID:2841); neuromyelitis optica (Disease Ontology:DOID:8869)", "pathway": " (dme:Dmel_CG2054); (R-DME-189085); (R-DME-6798695)", "pathway_count": 3, "publication_count": 5, "publication_id_list": "10731132;12537569;12537572;18327897;9662472", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 7, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "O17421", "ec_number_list": "3.2.1.17;1.1.1.42;3.5.1.28;3.2.1.14;3.5.3.1;4.1.2.13;3.1.3.48;1.16.3.1;2.7.1.35;2.3.2.5;3.4.19.9;3.4.24.-;2.7.10.2;3.6.1.5;3.5.1.3;3.3.2.6;3.5.4.5;5.4.2.2;3.4.17.13;3.2.1.-", "go_molecular_function": "GO:0004568 chitinase activity;GO:0008843 endochitinase activity;GO:0008061 chitin binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0005615 extracellular space;GO:0098591 external side of apical plasma membrane", "go_biological_process": "GO:0042060 wound healing;GO:0000272 polysaccharide catabolic process;GO:0006032 chitin catabolic process;GO:0008362 chitin-based embryonic cuticle biosynthetic process;GO:0008363 larval chitin-based cuticle development", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q9W092-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9W0Z5-1", "uniprot_id": "Q9W0Z5_DROME", "mass": 58337.0, "length": 536, "protein_name": "Neural proliferation differentiation and control protein 1", "gene_name": "Atf-2", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform B", "refseq_ac": "NP_611974", "gene_names_uniprotkb": "Atf-2; CG30420; CG3749; CG44247; Dmel\\CG44247; Dmel_CG44247; FBgn0050420", "gene_names_refseq": "Atf-2; CG30420; CG3749; CG44247; Dmel\\CG44247; FBgn0050420", "protein_names_uniprotkb": "Neural proliferation differentiation and control protein 1", "protein_names_refseq": "CG44247-PB; uncharacterized protein, isoform B", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG44247)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "Q95TP1;Q9W0Z3", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9W0Z5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9W130-1", "uniprot_id": "CP9C1_DROME", "mass": 60538.0, "length": 522, "protein_name": "Cytochrome P450 9c1", "gene_name": "Cyp9c1", "organism": "Fruit fly", "refseq_name": "cytochrome P450 9c1", "refseq_ac": "NP_523850", "gene_names_uniprotkb": "Cyp9c1; CG3616", "gene_names_refseq": "9c1; CG3616; CYP9C1; Cyp9C1; Cyp9c1; Dmel\\CG3616; P-450; P450", "protein_names_uniprotkb": "Cytochrome P450 9c1; 1.14.-.-; CYPIXC1", "protein_names_refseq": "CG3616-PA; Cyp9c1-PA; cytochrome P450 9c1; cytochrome P450-9c1", "tax_id": 7227, "disease": "alcohol dependence (Disease Ontology:DOID:0050741); thrombosis (Disease Ontology:DOID:0060903); alcohol-associated liver disease (Disease Ontology:DOID:0070658); B-lymphoblastic leukemia/lymphoma (Disease Ontology:DOID:0080630); acute necrotizing pancreatitis (Disease Ontology:DOID:0080998); hypertension (Disease Ontology:DOID:10763); essential hypertension (Disease Ontology:DOID:10825); membranous glomerulonephritis (Disease Ontology:DOID:10976); hydronephrosis (Disease Ontology:DOID:11111); cholestasis (Disease Ontology:DOID:13580); depressive disorder (Disease Ontology:DOID:1596); anxiety disorder (Disease Ontology:DOID:2030); arteriosclerosis (Disease Ontology:DOID:2349); glomerulonephritis (Disease Ontology:DOID:2921); familial Mediterranean fever (Disease Ontology:DOID:2987); brain infarction (Disease Ontology:DOID:3454); liver cirrhosis (Disease Ontology:DOID:5082); oral submucous fibrosis (Disease Ontology:DOID:5773); end stage renal disease (Disease Ontology:DOID:783); chronic myeloid leukemia (Disease Ontology:DOID:8552); pulmonary embolism (Disease Ontology:DOID:9477); acute lymphoblastic leukemia (Disease Ontology:DOID:9952)", "pathway": " (dme:Dmel_CG3616)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "10731132;12537569;12537572;8676871", "class_list": "", "function": "May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 22, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q24124", "ec_number_list": "", "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0004497 monooxygenase activity;GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q9W130-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9W133-1", "uniprot_id": "ADCK_DROME", "mass": 59859.0, "length": 518, "protein_name": "AarF domain-containing kinase 1", "gene_name": "Adck1", "organism": "Fruit fly", "refseq_name": "aarF domain containing kinase 1, isoform B", "refseq_ac": "NP_001286851", "gene_names_uniprotkb": "Adck1; Adck; CG3608", "gene_names_refseq": "ADCK1; Adck1; Adck; CG3608; Dmel\\CG3608; cg3608; dADCK1", "protein_names_uniprotkb": "AarF domain-containing kinase 1; 2.7.-.-", "protein_names_refseq": "Adck1-PB; CG3608-PB; aarF domain containing kinase 1, isoform B; aarF domain containing kinase; aarf domain-containing kinase 1", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG3608)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "10731132;12537569;12537572;31125351;31175694", "class_list": "", "function": "Essential for maintaining mitochondrial cristae formation and mitochondrial function by acting via YME1L1 to regulate the mitochondrial structural proteins Opa1 and Mitofilin (PubMed:31125351). This function is likely to be kinase-independent (By similarity). Functions in tracheal development and larval molting probably by acting in sterol modification and/or intracellular lipid trafficking (PubMed:31175694). The action of this enzyme is not yet clear (Probable). It is not known if it has protein kinase activity and what type of substrate it would phosphorylate (Ser, Thr or Tyr) (Probable)., [UniProtKB, UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004672 protein kinase activity;GO:0005524 ATP binding", "go_cellular_component": "GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0055088 lipid homeostasis;GO:0007005 mitochondrion organization;GO:1903852 positive regulation of cristae formation;GO:0010637 negative regulation of mitochondrial fusion", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q9W133-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9W1B0-1", "uniprot_id": "GEK_DROME", "mass": 186724.0, "length": 1637, "protein_name": "Serine/threonine-protein kinase Genghis Khan", "gene_name": "gek", "organism": "Fruit fly", "refseq_name": "genghis khan", "refseq_ac": "NP_523837", "gene_names_uniprotkb": "gek; CG4012", "gene_names_refseq": "CG4012; Dmel\\CG4012; Gek; MRCKalpha; MRCK; MdaPk; Mrck; anon-WO0200864.1; dMRCK; gek; l(2)09373", "protein_names_uniprotkb": "Serine/threonine-protein kinase Genghis Khan; 2.7.11.1", "protein_names_refseq": "CG4012-PA; chingis khan; gek-PA; genghis kahn; genghis khan; myotonic dystrophy kinase related", "tax_id": 7227, "disease": "cerebral cavernous malformation (Disease Ontology:DOID:0060669); azoospermia (Disease Ontology:DOID:14227)", "pathway": " (dme:Dmel_CG4012); (R-DME-9013149); (R-DME-9013406)", "pathway_count": 3, "publication_count": 6, "publication_id_list": "10731132;12537569;12537572;17372656;18327897;9371783", "class_list": "", "function": "Acts as a downstream effector for the regulation of actin polymerization by Cdc42., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "O44368", "ec_number_list": "2.7.11.1;2.7.11.17;2.7.11.13;2.7.11.24;3.1.4.4;2.7.11.22;3.6.5.2;2.7.11.21;2.7.10.2;5.6.1.8;2.7.11.11;2.7.11.23;2.7.12.1;2.7.11.25;2.7.11.12;2.7.12.2;2.7.10.1;2.7.11.39;2.3.2.26", "go_molecular_function": "GO:0004672 protein kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0008270 zinc ion binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005856 cytoskeleton;GO:0030424 axon;GO:0030426 growth cone", "go_biological_process": "GO:0008154 actin polymerization or depolymerization;GO:0031032 actomyosin structure organization;GO:0030833 regulation of actin filament polymerization;GO:0008039 synaptic target recognition", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q9W1B0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9W1H4-1", "uniprot_id": "DNLI1_DROME", "mass": 84719.0, "length": 747, "protein_name": "DNA ligase 1", "gene_name": "DNAlig1", "organism": "Fruit fly", "refseq_name": "DNA ligase 1", "refseq_ac": "NP_611843", "gene_names_uniprotkb": "DNAlig1; CG5602; DNA-ligI", "gene_names_refseq": "CG5602; DNA-lig1; DNA-ligI; DNAlig1; Dlig-I; DmDNA Lig I; Dmel\\CG5602; LIG1; dDNAlig1", "protein_names_uniprotkb": "DNA ligase 1; 6.5.1.1; DNA ligase I; DmDNA Lig I", "protein_names_refseq": "CG5602-PA; DNA ligase 1; DNA ligase I; DNAlig1-PA", "tax_id": 7227, "disease": "immunodeficiency 96 (Disease Ontology:DOID:0061066); cancer (Disease Ontology:DOID:162); primary immunodeficiency disease (Disease Ontology:DOID:612); inherited metabolic disorder (Disease Ontology:DOID:655); epilepsy with generalized tonic-clonic seizures (Disease Ontology:DOID:7725)", "pathway": " (dme:Dmel_CG5602); (R-DME-5358565); (R-DME-5358606); (R-DME-5651801); (R-DME-6782210); (R-DME-69183)", "pathway_count": 6, "publication_count": 7, "publication_id_list": "10731132;12537569;12537572;17372656;17937809;18327897;37268618", "class_list": "", "function": "DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 7, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q960P4", "ec_number_list": "2.7.7.6;3.1.11.2;3.1.-.-;5.6.2.4;2.7.11.22;2.7.11.23;3.6.4.13;5.6.2.3;5.2.1.8;2.7.7.7;3.1.11.-;6.5.1.1;3.4.19.12", "go_molecular_function": "GO:0003677 DNA binding;GO:0005524 ATP binding;GO:0003910 DNA ligase (ATP) activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0071897 DNA biosynthetic process;GO:0006273 lagging strand elongation;GO:0006281 DNA repair;GO:0006310 DNA recombination;GO:0051301 cell division", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q9W1H4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9W1I9-1", "uniprot_id": "FKBP6_DROME", "mass": 51838.0, "length": 455, "protein_name": "Inactive peptidyl-prolyl cis-trans isomerase shutdown", "gene_name": "shu", "organism": "Fruit fly", "refseq_name": "shutdown", "refseq_ac": "NP_611837", "gene_names_uniprotkb": "shu; CG4735", "gene_names_refseq": "CG4735; Dmel\\CG4735; Shu; shu", "protein_names_uniprotkb": "Inactive peptidyl-prolyl cis-trans isomerase shutdown", "protein_names_refseq": "CG4735-PA; Shut-down; shu-PA; shut down; shutdown", "tax_id": 7227, "disease": "spermatogenic failure 77 (Disease Ontology:DOID:0070576); male infertility (Disease Ontology:DOID:12336); Williams-Beuren syndrome (Disease Ontology:DOID:1928)", "pathway": " (dme:Dmel_CG4735)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "10731132;10978289;12537572;22753781;22902557", "class_list": "", "function": "Co-chaperone required during oogenesis to repress transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Acts as a co-chaperone via its interaction with Hsp83/HSP90 and is required for the biogenesis of all three piRNA major populations., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0051879 Hsp90 protein binding;GO:0003755 peptidyl-prolyl cis-trans isomerase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0043186 P granule;GO:0070725 Yb body", "go_biological_process": "GO:0007283 spermatogenesis;GO:0048477 oogenesis;GO:0034587 piRNA processing;GO:0051321 meiotic cell cycle;GO:0010526 transposable element silencing", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q9W1I9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9W1N5-1", "uniprot_id": "GR59F_DROME", "mass": 47559.0, "length": 406, "protein_name": "Putative gustatory receptor 59f", "gene_name": "Gr59f", "organism": "Fruit fly", "refseq_name": "gustatory receptor 59f", "refseq_ac": "NP_788432", "gene_names_uniprotkb": "Gr59f; CG33150; GR59E.1", "gene_names_refseq": "59E.1; CG33150; CG5365; Dmel\\CG33150; GR59E.1; GR59f; Gr59E1; Gr59f", "protein_names_uniprotkb": "Putative gustatory receptor 59f", "protein_names_refseq": "CG33150-PA; Gr59f-PA; gustatory receptor 59E.1; gustatory receptor 59f", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG33150)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "10710312;10731132;11516643;12537572;22031876", "class_list": "", "function": "Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates., [UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0015276 ligand-gated monoatomic ion channel activity;GO:0008527 taste receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane;GO:0030424 axon;GO:0030425 dendrite;GO:0043025 neuronal cell body", "go_biological_process": "GO:0008049 male courtship behavior;GO:0007165 signal transduction;GO:0034220 monoatomic ion transmembrane transport;GO:0007635 chemosensory behavior;GO:0050912 detection of chemical stimulus involved in sensory perception of taste", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q9W1N5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9W1U4-1", "uniprot_id": "KI59C_DROME", "mass": 70053.0, "length": 626, "protein_name": "Kinesin-like protein Klp59C", "gene_name": "Klp59C", "organism": "Fruit fly", "refseq_name": "Kinesin-like protein at 59C", "refseq_ac": "NP_611759", "gene_names_uniprotkb": "Klp59C; CG3219", "gene_names_refseq": "CG3219; DmCG3219; DmKLP59C; DmKlp59C; Dmel\\CG3219; KIF 2B; KIF2A/B/C; KLP59C; Klp59C", "protein_names_uniprotkb": "Kinesin-like protein Klp59C; Kinesin-like protein at cytological position 59C", "protein_names_refseq": "CG3219-PA; Kinesin-like protein at 59C; Kinesin13C; Klp59C-PA; kinesin-13", "tax_id": 7227, "disease": "colorectal cancer (Disease Ontology:DOID:9256)", "pathway": " (dme:Dmel_CG3219); (R-DME-983189)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "10731132;12537572;14681690", "class_list": "", "function": "Required during anaphase to drive sister chromatid separation to actively depolymerize kinetochore microtubules at their kinetochore-associated plus ends, thereby contributing to chromatid mobility through a 'Pac-man' mechanism., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0008017 microtubule binding;GO:0016887 ATP hydrolysis activity;GO:0003777 microtubule motor activity;GO:0003774 cytoskeletal motor activity", "go_cellular_component": "GO:0005828 kinetochore microtubule;GO:0000922 spindle pole;GO:0005737 cytoplasm;GO:0005813 centrosome;GO:0005819 spindle", "go_biological_process": "GO:0007059 chromosome segregation;GO:0051301 cell division;GO:0007018 microtubule-based movement", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9W1U4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9W1V1-1", "uniprot_id": "ANM7_DROME", "mass": 77946.0, "length": 690, "protein_name": "Protein arginine N-methyltransferase 7", "gene_name": "Art7", "organism": "Fruit fly", "refseq_name": "arginine methyltransferase 7", "refseq_ac": "NP_611753", "gene_names_uniprotkb": "Art7; CG9882", "gene_names_refseq": "Art7; CG9882; DART7; Dmel\\CG9882; PRMT7; dart7", "protein_names_uniprotkb": "Protein arginine N-methyltransferase 7; 2.1.1.-; Dart7", "protein_names_refseq": "Art7-PB; CG9882-PB; arginine methyltransferase 7", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG9882)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "10731132;12537569;12537572;14705965;18369183", "class_list": "", "function": "Essential arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA). Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins SmD1 and SmD3., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "B5X512;Q8MYV1", "ec_number_list": "", "go_molecular_function": "GO:0016274 protein-arginine N-methyltransferase activity;GO:0042054 histone methyltransferase activity;GO:0035243 protein-arginine omega-N symmetric methyltransferase activity", "go_cellular_component": "", "go_biological_process": "GO:0006338 chromatin remodeling;GO:0006355 regulation of DNA-templated transcription;GO:0018216 peptidyl-arginine methylation", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q9W1V1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9W1V3-1", "uniprot_id": "FBRL_DROME", "mass": 34637.0, "length": 344, "protein_name": "rRNA 2'-O-methyltransferase fibrillarin", "gene_name": "Fib", "organism": "Fruit fly", "refseq_name": "fibrillarin", "refseq_ac": "NP_523817", "gene_names_uniprotkb": "Fib; CG9888", "gene_names_refseq": "CG9888; Dmel\\CG9888; Fibri; Fib; GCR-6; GCR6; Pen59C5; dFib; fibrillarin; fib; pen59C5", "protein_names_uniprotkb": "rRNA 2'-O-methyltransferase fibrillarin; 2.1.1.-; Histone-glutamine methyltransferase", "protein_names_refseq": "CG9888-PA; Fib-PA; fibrillarin", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG9888); (R-DME-6791226)", "pathway_count": 2, "publication_count": 6, "publication_id_list": "10731132;12537569;12537572;19229318;22242017;2884623", "class_list": "", "function": "S-adenosyl-L-methionine-dependent methyltransferase that has the ability to methylate both RNAs and proteins. Involved in pre-rRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in pre-ribosomal RNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA. Also acts as a protein methyltransferase by mediating methylation of 'Gln-105' of histone H2A (H2AQ105me), a modification that impairs binding of the FACT complex and is specifically present at 35S ribosomal DNA locus (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q24348;Q8IGK5", "ec_number_list": "3.6.4.13;3.1.13.-;2.1.1.-", "go_molecular_function": "GO:0003723 RNA binding;GO:0008649 rRNA methyltransferase activity;GO:1990259 histone H2AQ104 methyltransferase activity", "go_cellular_component": "GO:0005730 nucleolus;GO:0015030 Cajal body;GO:0001651 dense fibrillar component;GO:0031428 box C/D methylation guide snoRNP complex;GO:0032040 small-subunit processome", "go_biological_process": "GO:0031167 rRNA methylation;GO:0000494 box C/D sno(s)RNA 3'-end processing;GO:0000451 rRNA 2'-O-methylation;GO:0000452 snoRNA guided rRNA 2'-O-methylation", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q9W1V3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9W1X8-1", "uniprot_id": "FCL_DROME", "mass": 36123.0, "length": 321, "protein_name": "Probable GDP-L-fucose synthase", "gene_name": "Gmer", "organism": "Fruit fly", "refseq_name": "GDP-4-keto-6-deoxy-D-mannose 3,5-epimerase/4-reductase", "refseq_ac": "NP_611734", "gene_names_uniprotkb": "Gmer; CG3495", "gene_names_refseq": "CG3495; DmGMER; Dmel\\CG3495; GER; Gmer; gmer; l(2)SH1931", "protein_names_uniprotkb": "Probable GDP-L-fucose synthase; 1.1.1.271; GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase-4-reductase; GER; Protein FX", "protein_names_refseq": "CG3495-PA; GDP-4-keto-6-deoxy-D-mannose 3,5-epimerase/4-reductase; GDP-keto-6-deoxymannose 3,5-epimerase/4-reductase; Gmer-PA; lethal (2) SH1931", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG3495); (R-DME-6787639)", "pathway_count": 2, "publication_count": 5, "publication_id_list": "10731132;11698403;12537569;12537572;16650000", "class_list": "", "function": "Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q1H8X1;Q8MS16", "ec_number_list": "1.1.1.271", "go_molecular_function": "GO:0050577 GDP-L-fucose synthase activity;GO:0047918 GDP-mannose 3,5-epimerase activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0042351 'de novo' GDP-L-fucose biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q9W1X8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9W1Y1-1", "uniprot_id": "EMC89_DROME", "mass": 22781.0, "length": 203, "protein_name": "ER membrane protein complex subunit 8/9 homolog", "gene_name": "EMC8-9", "organism": "Fruit fly", "refseq_name": "ER membrane protein complex subunit 8/9", "refseq_ac": "NP_611731", "gene_names_uniprotkb": "EMC8-9; CG3501", "gene_names_refseq": "BcDNA:SD01117; CG3501; Dmel\\CG3501; EMC8-9; EMC8/9; emc8/9", "protein_names_uniprotkb": "ER membrane protein complex subunit 8/9 homolog", "protein_names_refseq": "CG3501-PA; EMC8-9-PA; ER membrane protein complex 8-9; ER membrane protein complex subunit 8/9; endoplasmic reticulum membrane protein complex 8/9; subunit 8/9 of EMC", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG3501)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "10731132;12537572;31263175", "class_list": "", "function": "Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized multi-pass membrane proteins like rhodopsins., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0072546 EMC complex;GO:0005789 endoplasmic reticulum membrane;GO:0012505 endomembrane system", "go_biological_process": "GO:0071816 tail-anchored membrane protein insertion into ER membrane;GO:0045050 protein insertion into ER membrane by stop-transfer membrane-anchor sequence", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9W1Y1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9W223-1", "uniprot_id": "CP6D2_DROME", "mass": 58679.0, "length": 512, "protein_name": "Probable cytochrome P450 6d2", "gene_name": "Cyp6d2", "organism": "Fruit fly", "refseq_name": "cytochrome P450 6d2", "refseq_ac": "NP_611698", "gene_names_uniprotkb": "Cyp6d2; CG4373", "gene_names_refseq": "6d2; CG4373; Cyp6d2; Dmel\\CG4373", "protein_names_uniprotkb": "Probable cytochrome P450 6d2; 1.14.-.-; CYPVID2", "protein_names_refseq": "CG4373-PA; Cyp6d2-PA; cytochrome P450 6d2; cytochrome P450", "tax_id": 7227, "disease": "alcohol-associated liver disease (Disease Ontology:DOID:0070658); B-lymphoblastic leukemia/lymphoma (Disease Ontology:DOID:0080630); prostate cancer (Disease Ontology:DOID:10283); Alzheimer's disease (Disease Ontology:DOID:10652); essential hypertension (Disease Ontology:DOID:10825); familial Mediterranean fever (Disease Ontology:DOID:2987); oral submucous fibrosis (Disease Ontology:DOID:5773); chronic myeloid leukemia (Disease Ontology:DOID:8552); acute lymphoblastic leukemia (Disease Ontology:DOID:9952)", "pathway": " (dme:Dmel_CG4373)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "10731132;12537572", "class_list": "", "function": "May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 9, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0004497 monooxygenase activity;GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:1901563 response to camptothecin", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q9W223-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9W256-1", "uniprot_id": "DPOE4_DROME", "mass": 17370.0, "length": 155, "protein_name": "DNA polymerase epsilon subunit 4", "gene_name": "PolE4", "organism": "Fruit fly", "refseq_name": "DNA polymerase epsilon subunit 4, isoform B", "refseq_ac": "NP_001163253", "gene_names_uniprotkb": "PolE4; CG11301; DNApolE4; Mes4; NF-Yc", "gene_names_refseq": "11301; BcDNA:GM21739; CG11301; Dmel\\CG11301; MES4; Mes4; NF-Yc; PolE4", "protein_names_uniprotkb": "DNA polymerase epsilon subunit 4; DNA polymerase II subunit 4; Mesoderm-expressed 4", "protein_names_refseq": "CG11301-PB; DNA polymerase epsilon subunit 4, isoform B; Mes4; Mesoderm-expressed 4; NF-YC-like; PolE4-PB", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG11301); (R-DME-110314); (R-DME-5651801); (R-DME-5656169); (R-DME-5696400); (R-DME-6782135); (R-DME-68952); (R-DME-68962)", "pathway_count": 8, "publication_count": 4, "publication_id_list": "10731132;12537569;12537572;19150446", "class_list": "", "function": "Accessory component of the DNA polymerase epsilon complex (By similarity). Participates in DNA repair and in chromosomal DNA replication (By similarity). Has a role in cell cycle progression (PubMed:19150446). Required for wing morphogenesis (PubMed:19150446)., [UniProtKB, UniProtKB, PubMed, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q8MSF2", "ec_number_list": "", "go_molecular_function": "GO:0046982 protein heterodimerization activity", "go_cellular_component": "GO:0008622 epsilon DNA polymerase complex;GO:0005634 nucleus", "go_biological_process": "GO:0006261 DNA-templated DNA replication", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q9W256-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9W2P0-1", "uniprot_id": "DGT3_DROME", "mass": 65823.0, "length": 565, "protein_name": "Augmin complex subunit dgt3", "gene_name": "dgt3", "organism": "Fruit fly", "refseq_name": "dim gamma-tubulin 3", "refseq_ac": "NP_611533", "gene_names_uniprotkb": "dgt3; CG3221", "gene_names_refseq": "CG3221; Dgt3; Dmel\\CG3221; dgt3; dim", "protein_names_uniprotkb": "Augmin complex subunit dgt3; Dim gamma-tubulin 3", "protein_names_refseq": "CG3221-PB; dgt3-PB; dim gamma-tubulin 3", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG3221)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "10731132;12537569;12537572;17412918;18443220;19369198", "class_list": "", "function": "As part of the augmin complex, plays a role in centrosome-independent generation of spindle microtubules (PubMed:18443220). The complex is required for mitotic spindle assembly through its involvement in localizing gamma-tubulin to spindle microtubules (PubMed:17412918)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "C9QP53;Q7K3C0", "ec_number_list": "", "go_molecular_function": "GO:0030674 protein-macromolecule adaptor activity", "go_cellular_component": "GO:0005819 spindle;GO:0005874 microtubule;GO:0070652 HAUS complex", "go_biological_process": "GO:0010968 regulation of microtubule nucleation;GO:0051301 cell division;GO:0090307 mitotic spindle assembly;GO:0007088 regulation of mitotic nuclear division;GO:0007098 centrosome cycle", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q9W2P0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9W332-1", "uniprot_id": "CUBN_DROME", "mass": 418179.0, "length": 3750, "protein_name": "Cubilin homolog", "gene_name": "Cubn", "organism": "Fruit fly", "refseq_name": "cubilin", "refseq_ac": "NP_727348", "gene_names_uniprotkb": "Cubn; CG32702", "gene_names_refseq": "CG2996; CG32702; CT7882; Cubn; Dmel\\CG32702; cubilin; dCubn; tok-like", "protein_names_uniprotkb": "Cubilin homolog", "protein_names_refseq": "CG32702-PB; Cubn-PB; TMPRSS6 iron sensing; cubilin ortholog; cubilin; dCubilin", "tax_id": 7227, "disease": "pre-eclampsia (Disease Ontology:DOID:10591); coronary artery disease (Disease Ontology:DOID:3393); kidney disease (Disease Ontology:DOID:557)", "pathway": " (dme:Dmel_CG32702)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "10731132;12537569;12537572;23264686", "class_list": "", "function": "Required in the nephrocyte for normal uptake of proteins and elimination of toxins, and for maintenance of endocytic trafficking structures. May function together with Amnionless., [UniProtKB, PubMed]", "predicted_glycosites": 41, "predicted_n_glycosites": 41, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 41, "binding_glycan_count": 0, "secondary_ac_list": "Q8T4G4", "ec_number_list": "", "go_molecular_function": "GO:0005509 calcium ion binding;GO:0038024 cargo receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0043235 receptor complex", "go_biological_process": "GO:0097017 renal protein absorption;GO:0015031 protein transport;GO:0072583 clathrin-dependent endocytosis;GO:0097206 nephrocyte filtration", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q9W332-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9W351-1", "uniprot_id": "AAAS_DROME", "mass": 52279.0, "length": 466, "protein_name": "Aladin", "gene_name": "Aladin", "organism": "Fruit fly", "refseq_name": "aladin, isoform B", "refseq_ac": "NP_001285049", "gene_names_uniprotkb": "Aladin; CG16892", "gene_names_refseq": "ALADIN; Aladin; CG16892; Dmel\\CG16892; aladin", "protein_names_uniprotkb": "Aladin", "protein_names_refseq": "Aladin-PB; CG16892-PB; aladin, isoform B", "tax_id": 7227, "disease": "triple-A syndrome (Disease Ontology:DOID:0050602); achalasia (Disease Ontology:DOID:9164)", "pathway": " (dme:Dmel_CG16892); (R-DME-159227); (R-DME-159230); (R-DME-159231); (R-DME-159236); (R-DME-1855170); (R-DME-1855196); (R-DME-1855229); (R-DME-3108214); (R-DME-3301854); (R-DME-3371453); (R-DME-4085377); (R-DME-4551638); (R-DME-4615885); (R-DME-8980692)", "pathway_count": 15, "publication_count": 4, "publication_id_list": "10731132;12537569;12537572;26246606", "class_list": "", "function": "Involved in mitotic spindle assembly., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0000922 spindle pole;GO:0005635 nuclear envelope;GO:0005643 nuclear pore;GO:0012505 endomembrane system;GO:0072686 mitotic spindle", "go_biological_process": "GO:1902365 positive regulation of protein localization to spindle pole body;GO:0006913 nucleocytoplasmic transport;GO:0015031 protein transport;GO:0090307 mitotic spindle assembly;GO:0051028 mRNA transport", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q9W351-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9W354-1", "uniprot_id": "ERK7_DROME", "mass": 105715.0, "length": 916, "protein_name": "Extracellular signal-regulated kinase 7", "gene_name": "Erk7", "organism": "Fruit fly", "refseq_name": "extracellularly regulated kinase 7, isoform B", "refseq_ac": "NP_001188568", "gene_names_uniprotkb": "Erk7; CG32703", "gene_names_refseq": "CG17441; CG2309; CG32703; Dmel\\CG32703; ERK7; ERK; Erk7; Erk; erk", "protein_names_uniprotkb": "Extracellular signal-regulated kinase 7; 2.7.11.24", "protein_names_refseq": "CG32703-PB; Erk7-PB; extracellularly regulated kinase 7, isoform B", "tax_id": 7227, "disease": "breast cancer (Disease Ontology:DOID:1612)", "pathway": " (dme:Dmel_CG32703)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "10731132;12537572;21847093;25393288", "class_list": "", "function": "Atypical MAPK protein that regulates protein secretion in a kinase activity-dependent manner (PubMed:21847093, PubMed:25393288). In response to starvation regulates protein secretion by mediating transitional endoplasmic reticulum site disassembly (PubMed:21847093). Mediates inhibition of insulin-like peptide secretion upon disturbed ribosome biogenesis and acts as a downstream effector of TP53 (PubMed:25393288)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 3, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "M9MSN4", "ec_number_list": "2.7.11.17;2.7.11.1;2.7.11.13;2.7.11.24;2.7.11.22;2.7.11.21;5.6.1.8;2.7.11.11;2.7.11.23;2.7.12.1;2.7.11.25;2.7.11.12;2.7.12.2;2.7.10.2;2.7.11.39", "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0004707 MAP kinase activity;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005635 nuclear envelope;GO:0005737 cytoplasm;GO:0005789 endoplasmic reticulum membrane;GO:0036064 ciliary basal body", "go_biological_process": "GO:0050709 negative regulation of protein secretion;GO:0035556 intracellular signal transduction;GO:0009267 cellular response to starvation;GO:0045792 negative regulation of cell size;GO:0007030 Golgi organization", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q9W354-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9W396-1", "uniprot_id": "Q9W396_DROME", "mass": 25974.0, "length": 240, "protein_name": "Heterochromatin protein 1b, isoform A; Heterochromatin protein 1b, isoform B; Heterochromatin protein 1b, isoform C", "gene_name": "HP1b", "organism": "Fruit fly", "refseq_name": "heterochromatin protein 1b, isoform B", "refseq_ac": "NP_001162713", "gene_names_uniprotkb": "HP1b; CG7041; Dmel\\CG7041; Dmel_CG7041; HP1B; HP1; Hp1b; hp1b", "gene_names_refseq": "CG7041; Dmel\\CG7041; HP1B; HP1b; HP1; Hp1b; hp1b", "protein_names_uniprotkb": "Heterochromatin protein 1b, isoform A; Heterochromatin protein 1b, isoform B; Heterochromatin protein 1b, isoform C", "protein_names_refseq": "CG7041-PB; HP1b-PB; heterochromatin protein 1B; heterochromatin protein 1b, isoform B", "tax_id": 7227, "disease": "prostate cancer (Disease Ontology:DOID:10283); lung adenocarcinoma (Disease Ontology:DOID:3910)", "pathway": " (dme:Dmel_CG7041); (R-DME-983231); (R-DME-9843940)", "pathway_count": 3, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003682 chromatin binding", "go_cellular_component": "GO:0005634 nucleus;GO:0000791 euchromatin;GO:0000792 heterochromatin;GO:0005721 pericentric heterochromatin;GO:0010369 chromocenter", "go_biological_process": "GO:0031507 heterochromatin formation;GO:0031452 negative regulation of heterochromatin formation", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9W396-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9W3E1-1", "uniprot_id": "INT4_DROME", "mass": 113423.0, "length": 1022, "protein_name": "Integrator complex subunit 4", "gene_name": "IntS4", "organism": "Fruit fly", "refseq_name": "integrator 4", "refseq_ac": "NP_572488", "gene_names_uniprotkb": "IntS4; CG12113; l(1)G0095", "gene_names_refseq": "CG12113; Dmel\\CG12113; Int4; IntS4; l(1)G0095", "protein_names_uniprotkb": "Integrator complex subunit 4", "protein_names_refseq": "CG12113-PA; IntS4-PA; integrator 4; lethal (1) G0095", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG12113); (R-DME-6807505)", "pathway_count": 2, "publication_count": 9, "publication_id_list": "10731132;12537572;21078872;23097424;31530651;32966759;36180473;37995689;39032490", "class_list": "", "function": "Component of the integrator complex, a multiprotein complex that terminates RNA polymerase II (Pol II) transcription in the promoter-proximal region of genes (PubMed:21078872, PubMed:23097424, PubMed:32966759). The integrator complex provides a quality checkpoint during transcription elongation by driving premature transcription termination of transcripts that are unfavorably configured for transcriptional elongation: the complex terminates transcription by (1) catalyzing dephosphorylation of the C-terminal domain (CTD) of Pol II subunit Polr2A/Rbp1 and Spt5, and (2) degrading the exiting nascent RNA transcript via endonuclease activity (PubMed:32966759). The integrator complex is also involved in the 3'-end processing of the U7 snRNA, and also the spliceosomal snRNAs U1, U2, U4 and U5 (PubMed:21078872, PubMed:23097424)., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0000822 inositol hexakisphosphate binding", "go_cellular_component": "GO:0005634 nucleus;GO:0032039 integrator complex;GO:0160232 INTAC complex", "go_biological_process": "GO:0016180 snRNA processing;GO:0034472 snRNA 3'-end processing;GO:0160240 RNA polymerase II transcription initiation surveillance", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "Q9W3E1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9W3I9-1", "uniprot_id": "Q9W3I9_DROME", "mass": 53844.0, "length": 475, "protein_name": "TNF-receptor-associated factor 6", "gene_name": "Traf6", "organism": "Fruit fly", "refseq_name": "TNF-receptor-associated factor 6", "refseq_ac": "NP_511080", "gene_names_uniprotkb": "Traf6; 2; CG10961; DTRAF2; Dmel\\CG10961; Dmel_CG10961; EP325; TRAF-6; TRAF2; TRAF6; TRAF; Traf2; dTRAF2; dTRAF6; dTraf2; dTraf6; dtraf2; dtraf6; traf2; traf6", "gene_names_refseq": "CG10961; DTRAF2; Dmel\\CG10961; EP325; TRAF-6; TRAF2; TRAF6; TRAF; Traf2; Traf6/2; Traf6; dTRAF2; dTRAF6; dTraf2; dTraf6; dtraf2; dtraf6; traf2; traf6", "protein_names_uniprotkb": "TNF-receptor-associated factor 6", "protein_names_refseq": "CG10961-PA; EP325; TNF-receptor-associated factor 2; TNF-receptor-associated factor 6; Traf6-PA; tumor necrosis factor receptor 2", "tax_id": 7227, "disease": "intrinsic cardiomyopathy (Disease Ontology:DOID:0060036); hypohidrotic ectodermal dysplasia (Disease Ontology:DOID:14793); laryngeal carcinoma (Disease Ontology:DOID:2600)", "pathway": " (dme:Dmel_CG10961); (R-DME-445989); (R-DME-450302); (R-DME-450321); (R-DME-5689880); (R-DME-5689896); (R-DME-9020702); (R-DME-937039); (R-DME-937042); (R-DME-937072); (R-DME-975144); (R-DME-975163)", "pathway_count": 12, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity;GO:0035591 signaling adaptor activity;GO:0032813 tumor necrosis factor receptor superfamily binding;GO:0005164 tumor necrosis factor receptor binding", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0009898 cytoplasmic side of plasma membrane", "go_biological_process": "GO:0045087 innate immune response;GO:0046330 positive regulation of JNK cascade;GO:0043123 positive regulation of canonical NF-kappaB signal transduction;GO:0010508 positive regulation of autophagy;GO:0000209 protein polyubiquitination", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9W3I9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9W3J8-1", "uniprot_id": "DRC1_DROME", "mass": 88162.0, "length": 743, "protein_name": "Dynein regulatory complex protein 1 homolog", "gene_name": "CG10958", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": "NP_572445", "gene_names_uniprotkb": "CG10958", "gene_names_refseq": "CG10958; Dmel\\CG10958", "protein_names_uniprotkb": "Dynein regulatory complex protein 1 homolog", "protein_names_refseq": "CG10958-PA; uncharacterized protein", "tax_id": 7227, "disease": "Kartagener syndrome (Disease Ontology:DOID:0050144); visceral heterotaxy (Disease Ontology:DOID:0050545); spermatogenic failure 80 (Disease Ontology:DOID:0070579); primary ciliary dyskinesia 21 (Disease Ontology:DOID:0110596)", "pathway": " (dme:Dmel_CG10958)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "10731132;12537569;12537572", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005930 axoneme;GO:0005858 axonemal dynein complex", "go_biological_process": "GO:0060285 cilium-dependent cell motility;GO:0070286 axonemal dynein complex assembly;GO:0003352 regulation of cilium movement", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9W3J8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9W3L5-1", "uniprot_id": "DM7A_DROME", "mass": 60747.0, "length": 542, "protein_name": "DM7 family protein CG15333", "gene_name": "CG15333", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": "NP_572431", "gene_names_uniprotkb": "CG15333", "gene_names_refseq": "CG15333; CG18293; Dmel\\CG15333", "protein_names_uniprotkb": "DM7 family protein CG15333", "protein_names_refseq": "CG15333-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG15333)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "10731132;12537569;12537572;17989248", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A9YJU0;A9YJU1;A9YJU2;A9YJU3;A9YJU7;A9YJU9;A9YJV0;Q8MTT0", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q9W3L5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9W3Q4-1", "uniprot_id": "Q9W3Q4_DROME", "mass": 58618.0, "length": 552, "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG15478", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform B", "refseq_ac": "NP_001162692", "gene_names_uniprotkb": "Dmel\\CG15478; CG15478; Dmel_CG15478", "gene_names_refseq": "CG15478; Dmel\\CG15478", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "CG15478-PB; uncharacterized protein, isoform B", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG15478)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "Q960G0", "ec_number_list": "", "go_molecular_function": "GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9W3Q4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9W3V8-1", "uniprot_id": "ALG8_DROME", "mass": 57945.0, "length": 511, "protein_name": "Probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase", "gene_name": "xit", "organism": "Fruit fly", "refseq_name": "xiantuan", "refseq_ac": "NP_572355", "gene_names_uniprotkb": "xit; CG4542", "gene_names_refseq": "Alg8; CG4542; Dalg8; Dmel\\CG4542; Xit; dAlg8; xit", "protein_names_uniprotkb": "Probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase; 2.4.1.265; Asparagine-linked glycosylation protein 8 homolog; Dol-P-Glc:Glc(1)Man(9)GlcNAc(2)-PP-dolichyl alpha-1,3-glucosyltransferase; Dolichyl-P-Glc:Glc1Man9GlcNAc2-PP-dolichyl glucosyltransferase; Protein xiantuan", "protein_names_refseq": "CG4542-PA; xiantuan; xit-PA", "tax_id": 7227, "disease": "congenital disorder of glycosylation type I (Disease Ontology:DOID:0050570); polycystic liver disease 3 (Disease Ontology:DOID:0060976); congenital disorder of glycosylation Ih (Disease Ontology:DOID:0080560)", "pathway": " (dme:Dmel_CG4542); (R-DME-446193)", "pathway_count": 2, "publication_count": 4, "publication_id_list": "10731132;12537569;12537572;24681004", "class_list": "", "function": "Adds the second glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc(1)Man(9)GlcNAc(2)-PP-Dol (By similarity). Functions in developmental processes such as germband extension, the apical constriction of mesoderm precursor cells and ventral furrow formation in early embryogenesis prior to gastrulation (PubMed:24681004). Involved in the glycosylation and intracellular distribution of shg (E-cadherin) (PubMed:24681004). Function in cell intercalation in the lateral epidermis during germband extension may be due to its effect on shg (PubMed:24681004)., [UniProtKB, PubMed, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q058Z6", "ec_number_list": "2.4.1.265", "go_molecular_function": "GO:0042283 dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006488 dolichol-linked oligosaccharide biosynthetic process;GO:0006487 protein N-linked glycosylation", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q9W3V8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9W3Y4-1", "uniprot_id": "GA2PE_DROME", "mass": 104466.0, "length": 977, "protein_name": "GAS2-like protein pickled eggs", "gene_name": "pigs", "organism": "Fruit fly", "refseq_name": "pickled eggs, isoform B", "refseq_ac": "NP_001245550", "gene_names_uniprotkb": "pigs; CG3973", "gene_names_refseq": "CG3973; Dmel\\CG3973; pigs; pig", "protein_names_uniprotkb": "GAS2-like protein pickled eggs", "protein_names_refseq": "CG3973-PB; pickled eggs, isoform B; pigs-PB", "tax_id": 7227, "disease": "primary ciliary dyskinesia (Disease Ontology:DOID:9562)", "pathway": " (dme:Dmel_CG3973)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "10731132;12537569;12537572;20150280", "class_list": "", "function": "Essential for development and viability. Required for ovary development and oogenesis, and is essential for the development of the indirect flight muscles. May act as a negative regulator of the Notch signaling pathway in certain tissues, such as the muscle precursors and ovaries. May function as a linker protein between the actin and microtubule cytoskeletons., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q95TD5", "ec_number_list": "", "go_molecular_function": "GO:0008017 microtubule binding;GO:0051015 actin filament binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005856 cytoskeleton;GO:0005938 cell cortex", "go_biological_process": "GO:0031110 regulation of microtubule polymerization or depolymerization;GO:0051764 actin crosslink formation;GO:0045746 negative regulation of Notch signaling pathway;GO:0001578 microtubule bundle formation;GO:1904825 protein localization to microtubule plus-end", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q9W3Y4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9W401-1", "uniprot_id": "CISY_DROME", "mass": 51574.0, "length": 464, "protein_name": "Probable citrate synthase, mitochondrial", "gene_name": "Cs1", "organism": "Fruit fly", "refseq_name": "knockdown, isoform A", "refseq_ac": "NP_572319", "gene_names_uniprotkb": "Cs1; CG3861; kdn; l(1)G0030", "gene_names_refseq": "BEST:GM01832; CG 3861; CG3861; CS; Csyn; Dmel\\CG3861; Kdn; csyn; kdn; l (1) G0030; l(1)G0030; l(1)G0033; l(1)G0159", "protein_names_uniprotkb": "Probable citrate synthase, mitochondrial; 2.3.3.16; Protein knockdown", "protein_names_refseq": "CG3861-PA; citrate synthase; kdn-PA; knockdown, isoform A; lethal (1) G0030", "tax_id": 7227, "disease": "limb ischemia (Disease Ontology:DOID:0050852); left ventricular failure (Disease Ontology:DOID:0051064); hypertrophic cardiomyopathy (Disease Ontology:DOID:11984); dilated cardiomyopathy (Disease Ontology:DOID:12930); hypothyroidism (Disease Ontology:DOID:1459); bipolar disorder (Disease Ontology:DOID:3312); myocardial infarction (Disease Ontology:DOID:5844); congestive heart failure (Disease Ontology:DOID:6000); hyperthyroidism (Disease Ontology:DOID:7998); retinal degeneration (Disease Ontology:DOID:8466)", "pathway": " (dme:Dmel_CG3861); (R-DME-71403); (R-DME-9837999)", "pathway_count": 3, "publication_count": 5, "publication_id_list": "10731132;12537569;12537572;14680800;16648587", "class_list": "", "function": "Plays a role in controlling neuronal activity and seizure susceptibility., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 10, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q8T477", "ec_number_list": "2.7.1.23;1.1.1.40;1.1.1.38;1.1.1.39;1.2.4.2;1.1.1.35;1.1.1.-;1.1.1.62;1.1.1.51;1.1.1.53;2.3.1.37;3.5.3.1;1.4.1.3;2.7.11.2;2.7.11.-;7.1.2.2;1.2.4.1;3.4.21.53;7.1.1.2;6.2.1.4;4.98.1.1;1.-.-.-;1.1.1.239;1.1.1.37;4.2.1.3;3.4.21.92;5.6.2.3;1.2.1.3;6.1.1.5;1.8.1.4;1.3.8.1;1.3.8.5;1.1.1.41;2.3.1.-;2.8.3.5;2.3.-.-;2.3.1.9;4.2.1.2;2.3.3.16;5.3.3.21", "go_molecular_function": "GO:0036440 citrate synthase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0006099 tricarboxylic acid cycle;GO:0006101 citrate metabolic process;GO:0005975 carbohydrate metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q9W401-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9W485-1", "uniprot_id": "INT6_DROME", "mass": 137108.0, "length": 1284, "protein_name": "Integrator complex subunit 6", "gene_name": "IntS6", "organism": "Fruit fly", "refseq_name": "integrator 6, isoform C", "refseq_ac": "NP_001259259", "gene_names_uniprotkb": "IntS6; CG3125; l(1)G0060", "gene_names_refseq": "CG3125; Dmel\\CG3125; Int6; IntS6; l(1)G0060", "protein_names_uniprotkb": "Integrator complex subunit 6", "protein_names_refseq": "CG3125-PC; IntS6-PC; integrator 6, isoform C", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG3125); (R-DME-6807505)", "pathway_count": 2, "publication_count": 8, "publication_id_list": "10731132;12537572;21078872;23097424;31530651;32966759;37995689;39032490", "class_list": "", "function": "Component of the integrator complex, a multiprotein complex that terminates RNA polymerase II (Pol II) transcription in the promoter-proximal region of genes (PubMed:21078872, PubMed:23097424, PubMed:32966759, PubMed:37995689). The integrator complex provides a quality checkpoint during transcription elongation by driving premature transcription termination of transcripts that are unfavorably configured for transcriptional elongation: the complex terminates transcription by (1) catalyzing dephosphorylation of the C-terminal domain (CTD) of Pol II subunit Polr2A/Rbp1 and Spt5, and (2) degrading the exiting nascent RNA transcript via endonuclease activity (PubMed:32966759, PubMed:37995689). The integrator complex is also involved in the 3'-end processing of the U7 snRNA, and also the spliceosomal snRNAs U1, U2, U4 and U5 (PubMed:21078872, PubMed:23097424). Within the integrator complex, IntS6 acts as a substrate adapter for protein phosphatase 2A (PP2A) (PubMed:37995689)., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "Q960F1", "ec_number_list": "", "go_molecular_function": "GO:0030674 protein-macromolecule adaptor activity;GO:0019888 protein phosphatase regulator activity;GO:0140767 enzyme-substrate adaptor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0032039 integrator complex;GO:0160232 INTAC complex", "go_biological_process": "GO:0016180 snRNA processing;GO:0034472 snRNA 3'-end processing;GO:0160240 RNA polymerase II transcription initiation surveillance", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q9W485-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9W4M8-1", "uniprot_id": "DGT4_DROME", "mass": 21425.0, "length": 188, "protein_name": "Augmin complex subunit dgt4", "gene_name": "dgt4", "organism": "Fruit fly", "refseq_name": "dim gamma-tubulin 4, isoform B", "refseq_ac": "NP_001259231", "gene_names_uniprotkb": "dgt4; CG4865", "gene_names_refseq": "BcDNA:SD26403; CG4865; Dgt4; Dmel\\CG4865; EG0007.10; EG:EG0007.10; dgt4; msd3", "protein_names_uniprotkb": "Augmin complex subunit dgt4; Dim gamma-tubulin 4", "protein_names_refseq": "CG4865-PB; dgt4-PB; dim gamma-tubulin 4, isoform B; mitotic spindle density 3", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG4865)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "10731132;10731137;12537569;12537572;17412918;18443220;19369198", "class_list": "", "function": "As part of the augmin complex, plays a role in centrosome-independent generation of spindle microtubules (PubMed:18443220). The complex is required for mitotic spindle assembly through its involvement in localizing gamma-tubulin to spindle microtubules (PubMed:17412918)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "O97426;Q7K763", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005819 spindle;GO:0005874 microtubule;GO:0070652 HAUS complex", "go_biological_process": "GO:0010968 regulation of microtubule nucleation;GO:0051301 cell division;GO:0090307 mitotic spindle assembly;GO:0007088 regulation of mitotic nuclear division;GO:0007098 centrosome cycle", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q9W4M8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9W4S1-1", "uniprot_id": "GRCR2_DROME", "mass": 63369.0, "length": 582, "protein_name": "Glutaredoxin domain-containing cysteine-rich protein CG12206", "gene_name": "CG12206", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform A", "refseq_ac": "NP_570060", "gene_names_uniprotkb": "CG12206", "gene_names_refseq": "CG12206; Dmel\\CG12206", "protein_names_uniprotkb": "Glutaredoxin domain-containing cysteine-rich protein CG12206", "protein_names_refseq": "CG12206-PA; uncharacterized protein, isoform A", "tax_id": 7227, "disease": "autosomal recessive nonsyndromic deafness 25 (Disease Ontology:DOID:0110483)", "pathway": " (dme:Dmel_CG12206)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "10731132;12537572", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "GO:0007605 sensory perception of sound", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q9W4S1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9W4X7-1", "uniprot_id": "EI3G1_DROME", "mass": 29946.0, "length": 269, "protein_name": "Eukaryotic translation initiation factor 3 subunit G-1", "gene_name": "eIF3g1", "organism": "Fruit fly", "refseq_name": "eukaryotic translation initiation factor 3 subunit g1", "refseq_ac": "NP_570011", "gene_names_uniprotkb": "eIF3g1; CG8636; eIF3-S4; eIF3ga", "gene_names_refseq": "CG8636; Dmel\\CG8636; cg8636; eIF s4; eIF-3ga; eIF-3; eIF3-S4; eIF3G1; eIF3g1; eIF3ga; eIF3g", "protein_names_uniprotkb": "Eukaryotic translation initiation factor 3 subunit G-1; Eukaryotic translation initiation factor 3 RNA-binding subunit 1; Eukaryotic translation initiation factor 3 subunit 4-1; eIF-3 RNA-binding subunit 1", "protein_names_refseq": "CG8636-PA; eIF3g paralogue a; eIF3g1-PA; eukaryotic translation initiation factor 3 subunit g1", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG8636); (R-DME-156827); (R-DME-72649); (R-DME-72689); (R-DME-72695); (R-DME-72702)", "pathway_count": 6, "publication_count": 5, "publication_id_list": "10731132;12537569;12537572;17372656;18327897", "class_list": "", "function": "RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. This subunit can bind 18S rRNA., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003729 mRNA binding;GO:0003743 translation initiation factor activity", "go_cellular_component": "GO:0016282 eukaryotic 43S preinitiation complex;GO:0033290 eukaryotic 48S preinitiation complex;GO:0005852 eukaryotic translation initiation factor 3 complex", "go_biological_process": "GO:0000278 mitotic cell cycle;GO:0006413 translational initiation;GO:0001732 formation of cytoplasmic translation initiation complex", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q9W4X7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9W542-1", "uniprot_id": "Q9W542_DROME", "mass": 110427.0, "length": 986, "protein_name": "Myb-interacting protein 130", "gene_name": "mip130", "organism": "Fruit fly", "refseq_name": "Myb-interacting protein 130", "refseq_ac": "NP_569958", "gene_names_uniprotkb": "mip130; 86E4.4; CG3480; Dmel\\CG3480; Dmel_CG3480; EG:86E4.4; Mip130; TWIT; Twit; Twt; twit", "gene_names_refseq": "86E4.4; CG3480; Dmel\\CG3480; EG:86E4.4; Mip130/TWIT; Mip130/Twt; Mip130; TWIT; Twit; mip130; twit", "protein_names_uniprotkb": "Myb-interacting protein 130", "protein_names_refseq": "CG3480-PA; Myb-interacting protein 130; mip130-PA; twilight", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG3480); (R-DME-1538133)", "pathway_count": 2, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding", "go_cellular_component": "GO:0070176 DRM complex;GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0000785 chromatin;GO:0031523 Myb complex", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0006355 regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "Q9W542-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9W590-1", "uniprot_id": "LSG1_DROME", "mass": 70246.0, "length": 606, "protein_name": "Large subunit GTPase 1 homolog", "gene_name": "Ns3", "organism": "Fruit fly", "refseq_name": "nucleostemin 3, isoform B", "refseq_ac": "NP_001284779", "gene_names_uniprotkb": "Ns3; A60; BACN32G11.5; CG14788; Dmel\\CG14788; Dmel_CG14788; EG:BACN32G11.5; NS3; dNS3; dmNuc3; l(1)2Ad; l(1)BA11; l(1)G0431; ns3", "gene_names_refseq": "A60; BACN32G11.5; CG14788; Dmel\\CG14788; EG:BACN32G11.5; NS3; Ns3; dNS3; dmNuc3; l(1)2Ad; l(1)BA11; l(1)G0431; ns3", "protein_names_uniprotkb": "Large subunit GTPase 1 homolog; 3.6.1.-; Nucleostemin-3", "protein_names_refseq": "CG14788-PB; Ns3-PB; lethal (1) 2Ad; lethal (1) G0431; nucleostemin 3, isoform B; nucleostemin 3; nucleostemin ortholog 3", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG14788)", "pathway_count": 1, "publication_count": 15, "publication_id_list": "10731132;10731137;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;18327897;18628395;25589440;26109356;26109357", "class_list": "", "function": "GTPase required for the nuclear export of the 60S ribosomal subunit. Probably acts by mediating the release of Nmd3 from the 60S ribosomal subunit after export into the cytoplasm. Regulator of body size; acts in serotonergic neurons to regulate insulin signaling and thus exerts global growth control., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005783 endoplasmic reticulum;GO:0005829 cytosol;GO:0015030 Cajal body", "go_biological_process": "GO:0015031 protein transport;GO:0000054 ribosomal subunit export from nucleus;GO:0051168 nuclear export;GO:0046626 regulation of insulin receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "Q9W590-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9W5N0-1", "uniprot_id": "COA7_DROME", "mass": 29640.0, "length": 266, "protein_name": "Cytochrome c oxidase assembly factor 7 homolog", "gene_name": "Coa7", "organism": "Fruit fly", "refseq_name": "cytochrome c oxidase assembly factor 7, isoform A", "refseq_ac": "NP_001036323", "gene_names_uniprotkb": "Coa7; CG13865; CG40301; COA7; Dmel\\CG13865; Dmel_CG13865; FBgn0039965; dCOA7", "gene_names_refseq": "CG13865; CG40301; COA7; Coa7; Dmel\\CG13865; FBgn0039965; dCOA7", "protein_names_uniprotkb": "Cytochrome c oxidase assembly factor 7 homolog; Beta-lactamase hcp-like protein CG13865; Sel1 repeat-containing protein 1 homolog", "protein_names_refseq": "CG13865-PA; Coa7-PA; cytochrome c oxidase assembly factor 7, isoform A", "tax_id": 7227, "disease": "autosomal recessive spinocerebellar ataxia with axonal neuropathy 3 (Disease Ontology:DOID:0070465)", "pathway": " (dme:Dmel_CG13865)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "10731132;12537568;12537569;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357;29718187", "class_list": "", "function": "Required for locomotion. Probably involved in the regulation of formation/maintenance of motor neurons at presynaptic terminals at the neuromuscular junction., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q0KHN1", "ec_number_list": "", "go_molecular_function": "GO:0015035 protein-disulfide reductase activity", "go_cellular_component": "GO:0005758 mitochondrial intermembrane space", "go_biological_process": "GO:0033617 mitochondrial respiratory chain complex IV assembly;GO:0008535 respiratory chain complex IV assembly", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "Q9W5N0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9W5X9-1", "uniprot_id": "ATAT2_DROME", "mass": 32383.0, "length": 287, "protein_name": "Alpha-tubulin N-acetyltransferase 2", "gene_name": "lky", "organism": "Fruit fly", "refseq_name": "leaky", "refseq_ac": "NP_608365", "gene_names_uniprotkb": "lky; CG17003", "gene_names_refseq": "CG17003; Dmel\\CG17003; lky", "protein_names_uniprotkb": "Alpha-tubulin N-acetyltransferase 2; 2.3.1.108; Acetyltransferase mec-17 homolog 2; Alpha-TAT 2; Protein leaky; TAT 2", "protein_names_refseq": "CG17003-PA; leaky; lky-PA", "tax_id": 7227, "disease": "neurodegenerative disease (Disease Ontology:DOID:1289)", "pathway": " (dme:Dmel_CG17003)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "10731132;12537569;12537572;36342916", "class_list": "", "function": "Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules (PubMed:36342916). Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dynamically unstable microtubules before the enzyme is released (By similarity). Main acetyltransferase responsible for alpha-tubulin 'Lys-40' acetylation in germline cells during the early stages of oogenesis (PubMed:36342916). Required for normal egg chamber separation (PubMed:36342916)., [UniProtKB, HAMAP, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q8T8W1", "ec_number_list": "2.3.1.108", "go_molecular_function": "GO:0019799 tubulin N-acetyltransferase activity", "go_cellular_component": "GO:0005874 microtubule;GO:0090543 Flemming body;GO:0045169 fusome", "go_biological_process": "GO:0000226 microtubule cytoskeleton organization;GO:0048666 neuron development;GO:0070507 regulation of microtubule cytoskeleton organization", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q9W5X9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9XTM1-1", "uniprot_id": "EXOC5_DROME", "mass": 82031.0, "length": 710, "protein_name": "Exocyst complex component 5", "gene_name": "Sec10", "organism": "Fruit fly", "refseq_name": "secretory 10", "refseq_ac": "NP_651218", "gene_names_uniprotkb": "Sec10; CG6159", "gene_names_refseq": "CG6159; Dmel\\CG6159; P71; Sec10p; Sec10; dSec10; dsec10; sec10", "protein_names_uniprotkb": "Exocyst complex component 5; Exocyst complex component Sec10", "protein_names_refseq": "CG6159-PA; Sec10 ortholog; Sec10-PA; secretory 10", "tax_id": 7227, "disease": "obstructive nephropathy (Disease Ontology:DOID:0070314); bicuspid aortic valve disease (Disease Ontology:DOID:0080332)", "pathway": " (dme:Dmel_CG6159); (R-DME-264876); (R-DME-5620916)", "pathway_count": 3, "publication_count": 3, "publication_id_list": "10731132;12537569;12537572", "class_list": "", "function": "Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q95TZ8", "ec_number_list": "", "go_molecular_function": "GO:0008013 beta-catenin binding", "go_cellular_component": "GO:0098793 presynapse;GO:0000145 exocyst", "go_biological_process": "GO:0016080 synaptic vesicle targeting;GO:0015031 protein transport;GO:0046718 symbiont entry into host cell;GO:0016192 vesicle-mediated transport;GO:0000281 mitotic cytokinesis", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9XTM1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9XTN4-1", "uniprot_id": "Q9XTN4_DROME", "mass": 77514.0, "length": 704, "protein_name": "Brinker", "gene_name": "brk", "organism": "Fruit fly", "refseq_name": "brinker", "refseq_ac": "NP_511069", "gene_names_uniprotkb": "brk; BRK; Brk; CG9653; Dm brk; Dmel\\CG9653; Dmel_CG9653; ssg-1", "gene_names_refseq": "BRK; Brk; CG9653; Dm brk; Dmel\\CG9653; brk; ssg-1", "protein_names_uniprotkb": "Brinker", "protein_names_refseq": "CG9653-PA; brinker; brk-PA; small salivary glands-1", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG9653)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;16876822;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003676 nucleic acid binding;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0030514 negative regulation of BMP signaling pathway;GO:0010468 regulation of gene expression;GO:0035212 cell competition in a multicellular organism;GO:0007472 wing disc morphogenesis", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "Q9XTN4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9XYZ5-1", "uniprot_id": "DDB1_DROME", "mass": 126045.0, "length": 1140, "protein_name": "DNA damage-binding protein 1", "gene_name": "pic", "organism": "Fruit fly", "refseq_name": "piccolo", "refseq_ac": "NP_650257", "gene_names_uniprotkb": "pic; CG7769; DDB1", "gene_names_refseq": "0263/16; 1258/16; 1366/03; 153636_at; 263/16; CG7769; D-DDB1; DDB-1; DDB1; Dbd1; Ddb1; Dmel\\CG7769; PIC; d-ddb1; dDDB1; dDdb1; ddb1; l(3)87Dh; l(3)S136603; pic", "protein_names_uniprotkb": "DNA damage-binding protein 1; D-DDB1; Damage-specific DNA-binding protein 1; Protein piccolo", "protein_names_refseq": "CG7769-PA; DDB1; Damage-specific DNA binding protein 1; damaged DNA binding protein 1; drosophila damage-specific DNA-binding protein 1; pic-PA; piccolo", "tax_id": 7227, "disease": "xeroderma pigmentosum (Disease Ontology:DOID:0050427); communication disorder (Disease Ontology:DOID:2033)", "pathway": " (dme:Dmel_CG7769); (R-DME-110314); (R-DME-5696394); (R-DME-5696395); (R-DME-5696400); (R-DME-6781823); (R-DME-6782135); (R-DME-6782210); (R-DME-8951664)", "pathway_count": 9, "publication_count": 6, "publication_id_list": "10731132;10731138;12537572;16428319;18381890;27702999", "class_list": "", "function": "Protein, which is both involved in DNA repair and protein ubiquitination, as part of the UV-DDB complex and DCX (DDB1-CUL4-X-box) complexes, respectively (By similarity). Core component of the UV-DDB complex (UV-damaged DNA-binding protein complex), a complex that recognizes UV-induced DNA damage and recruit proteins of the nucleotide excision repair pathway (the NER pathway) to initiate DNA repair (By similarity). The UV-DDB complex preferentially binds to cyclobutane pyrimidine dimers (CPD), 6-4 photoproducts (6-4 PP), apurinic sites and short mismatches (By similarity). Also functions as a component of numerous distinct DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). The functional specificity of the DCX E3 ubiquitin-protein ligase complex is determined by the variable substrate recognition component recruited by DDB1 (By similarity). Required for degradation of gig (PubMed:18381890). Required for genomic stability in the face of endogenous DNA lesions and for the response to MMS-induced DNA damage (PubMed:16428319). Required for normal wing development (PubMed:16428319)., [UniProtKB, UniProtKB, PubMed, UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0035861 site of double-strand break", "go_biological_process": "GO:0006281 DNA repair;GO:0006974 DNA damage response;GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0016567 protein ubiquitination;GO:0045732 positive regulation of protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q9XYZ5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9XZ08-1", "uniprot_id": "EXT3_DROME", "mass": 111000.0, "length": 972, "protein_name": "Exostosin-3", "gene_name": "botv", "organism": "Fruit fly", "refseq_name": "brother of tout-velu", "refseq_ac": "NP_523790", "gene_names_uniprotkb": "botv; CG15110; DEXT3", "gene_names_refseq": "BcDNA:LD21192; Botv; CG15110; DEXT3; DEXTL3; DExt3; Dextl3; Dmel\\CG15110; EXTL3; Extl3; botv; dExt3", "protein_names_uniprotkb": "Exostosin-3; 2.4.1.223; Protein brother of tout-velu", "protein_names_refseq": "CG15110-PA; botv-PA; brother of tout velu; brother of tout-velo; brother of tout-velu; brother of ttv; brother-of-tout-velu; drosophila Ext-like 3", "tax_id": 7227, "disease": "hereditary multiple exostoses (Disease Ontology:DOID:206)", "pathway": " (dme:Dmel_CG15110); (R-DME-2022928)", "pathway_count": 2, "publication_count": 8, "publication_id_list": "10731132;10731138;11832488;12537572;14645127;14998928;15056609;23720043", "class_list": "", "function": "Glycosyltransferase required for the biosynthesis of heparan-sulfate and responsible for the alternating addition of beta-1-4-linked glucuronic acid (GlcA) and alpha-1-4-linked N-acetylglucosamine (GlcNAc) units to nascent heparan sulfate chains. Plays a central role in diffusion of morphogens hedgehog (hh), wingless (wg) and Decapentaplegic (dpp) via its role in heparan sulfate proteoglycans (HSPGs) biosynthesis, HSPGs being required for movement of Hh, Dpp and wg morphogens., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 4, "predicted_n_glycosites": 4, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 3, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.4.1.223", "go_molecular_function": "GO:0046872 metal ion binding;GO:0008375 acetylglucosaminyltransferase activity;GO:0016757 glycosyltransferase activity;GO:0001888 glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0016020 membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006044 N-acetylglucosamine metabolic process;GO:0016055 Wnt signaling pathway;GO:0015012 heparan sulfate proteoglycan biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q9XZ08-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9XZ14-1", "uniprot_id": "GOE_DROME", "mass": 100068.0, "length": 879, "protein_name": "Protein gone early", "gene_name": "goe", "organism": "Fruit fly", "refseq_name": "gone early, isoform C", "refseq_ac": "NP_001285350", "gene_names_uniprotkb": "goe; BcDNA:LD21405; CG9634; Dmel\\CG9634; Dmel_CG9634; Nepl2", "gene_names_refseq": "BcDNA:LD21405; CG9634; Dmel\\CG9634; Nepl2; goe", "protein_names_uniprotkb": "Protein gone early", "protein_names_refseq": "CG9634-PC; Neprilysin-like 2; goe-PC; gone early, isoform C", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG9634)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "10731132;10731138;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25420147;25589440;26109356;26109357", "class_list": "", "function": "Plays a role in the ovary in limiting the number of primordial germ cells (PGCs) that develop directly into gametes, allowing them instead to enter the developmental pathway that produces germline stem cells (GSCs) from PGCs and ensuring lifelong production of gametes from these GSCs. Negatively regulates epidermal growth factor receptor (Egfr) signaling. Probably down-regulates EGFR signaling on intermingled cells, a type of somatic stromal cell which contacts PGCs, and the resultant low level of signaling limits the proportion of PGCs which start gametogenesis, maintaining them in an undifferentiated proliferative state., [UniProtKB, PubMed]", "predicted_glycosites": 4, "predicted_n_glycosites": 4, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0006508 proteolysis;GO:0048477 oogenesis;GO:2000737 negative regulation of stem cell differentiation", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "Q9XZ14-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9XZT6-1", "uniprot_id": "DNK_DROME", "mass": 29088.0, "length": 250, "protein_name": "Deoxynucleoside kinase", "gene_name": "dnk", "organism": "Fruit fly", "refseq_name": "deoxyribonucleoside kinase, isoform B", "refseq_ac": "NP_001262722", "gene_names_uniprotkb": "dnk; CG5452", "gene_names_refseq": "CG5452; DM-dNK; DNK; Dm-dNK; DmdNK; Dmel\\CG5452; dNK; dnk", "protein_names_uniprotkb": "Deoxynucleoside kinase; 2.7.1.145; Deoxyribonucleoside kinase; Dm-dNK; Multispecific deoxynucleoside kinase", "protein_names_refseq": "2'-deoxynucleoside kinase; CG5452-PB; deoxyribonucleoside kinase, isoform B; deoxyribonucleoside; dnk-PB", "tax_id": 7227, "disease": "mitochondrial DNA depletion syndrome 2 (Disease Ontology:DOID:0080120); autosomal recessive progressive external ophthalmoplegia with mitochondrial DNA deletions 3 (Disease Ontology:DOID:0111523)", "pathway": " (dme:Dmel_CG5452); (R-DME-73614)", "pathway_count": 2, "publication_count": 10, "publication_id_list": "10446143;10692477;10731132;12537572;12741827;16008571;17372656;18327897;18384378;9461577", "class_list": "", "function": "Deoxyribonucleoside kinase that has a broad specificity phosphorylating thymidine, 2'-deoxyriboadenosine, 2'-deoxyribocytidine and 2'-deoxyriboguanosine. Specificity is higher for pyrimidine nucleosides. Several anti-viral and anti-cancer nucleoside analogs are also efficiently phosphorylated., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.1.145", "go_molecular_function": "GO:0004138 deoxyguanosine kinase activity;GO:0005524 ATP binding;GO:0016301 kinase activity;GO:0004849 uridine kinase activity;GO:0004137 deoxycytidine kinase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion", "go_biological_process": "GO:0071897 DNA biosynthetic process;GO:1901293 nucleoside phosphate biosynthetic process;GO:0043174 nucleoside salvage", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "Q9XZT6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9Y0A7-1", "uniprot_id": "AMOS_DROME", "mass": 22569.0, "length": 198, "protein_name": "Basic helix-loop-helix transcription factor amos", "gene_name": "amos", "organism": "Fruit fly", "refseq_name": "absent MD neurons and olfactory sensilla", "refseq_ac": "NP_477446", "gene_names_uniprotkb": "amos; CG10393; Roi; rolo", "gene_names_refseq": "Amos; CG10393; Dmel\\CG10393; Roi; Tft; amos; asolo; bHLHa10; rolo", "protein_names_uniprotkb": "Basic helix-loop-helix transcription factor amos; Absent MD neurons and olfactory sensilla protein; Amos protein; Reduced olfactory organs protein; Rough eye protein", "protein_names_refseq": "CG10393-PA; Rough-eye; absent MD neurons and olfactory sensilla; absent MD neurons; amos-PA; rough eye; tufted", "tax_id": 7227, "disease": "persistent hyperplastic primary vitreous (Disease Ontology:DOID:0060282); autosomal dominant nonsyndromic deafness 89 (Disease Ontology:DOID:0070612)", "pathway": " (dme:Dmel_CG10393)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "10707972;10707973;10731132;12537572", "class_list": "", "function": "Transcription factor involved in early neurogenesis; sensillum basiconica formation and maybe sensillum trichodea development. Promotes multiple dendritic (MD) neuron formation. Required for olfactory sensilla; regulated by lozenge (lz)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q0IGQ5;Q9VJ76", "ec_number_list": "", "go_molecular_function": "GO:0046982 protein heterodimerization activity;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0070888 E-box binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0008052 sensory organ boundary specification;GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0048813 dendrite morphogenesis;GO:0048663 neuron fate commitment", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q9Y0A7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9Y117-1", "uniprot_id": "GALT3_DROME", "mass": 76807.0, "length": 667, "protein_name": "Polypeptide N-acetylgalactosaminyltransferase 3", "gene_name": "Pgant3", "organism": "Fruit fly", "refseq_name": "polypeptide N-Acetylgalactosaminyltransferase 3", "refseq_ac": "NP_610256", "gene_names_uniprotkb": "Pgant3; CG4445", "gene_names_refseq": "BcDNA:GH09147; CG4445; Dmel\\CG4445; Pgant3; anon-WO0118547.119; pgant3; ppGalNAcT3", "protein_names_uniprotkb": "Polypeptide N-acetylgalactosaminyltransferase 3; 2.4.1.41; Protein-UDP acetylgalactosaminyltransferase 3; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 3; pp-GaNTase 3", "protein_names_refseq": "CG4445-PA; Pgant3-PA; polypeptide GalNAc transferase 3; polypeptide N-Acetylgalactosaminyltransferase 3", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG4445); (R-DME-913709)", "pathway_count": 2, "publication_count": 10, "publication_id_list": "10731132;12537569;12537572;12829714;16251381;18835818;20371600;20807760;22157008;25253852", "class_list": "", "function": "Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor (PubMed:12829714). It can both act as a peptide transferase that transfers GalNAc onto unmodified peptide substrates, and as a glycopeptide transferase that requires the prior addition of a GalNAc on a peptide before adding additional GalNAc moieties. Prefers EA2 as substrate. Has weak activity toward Muc5AC-3, -13 and -3/13 substrates (PubMed:12829714). Plays a critical role in the regulation of integrin-mediated cell adhesion during wing development by influencing, via glycosylation, the secretion and localization of the integrin ligand Tig to the basal cell layer interface (PubMed:18835818, PubMed:20371600, PubMed:20807760, PubMed:22157008). Might have a role in protein O-glycosylation in the Golgi and thereby in establishing and/or maintaining a proper secretory apparatus structure (PubMed:20807760). Together with Pgant35A, regulates integrin levels and activity-dependent integrin signaling at the synapse in neurons and muscles (PubMed:25253852)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 6, "predicted_n_glycosites": 6, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 6, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.4.1.-;2.4.1.41", "go_molecular_function": "GO:0046872 metal ion binding;GO:0030246 carbohydrate binding;GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005794 Golgi apparatus;GO:0005795 Golgi stack", "go_biological_process": "GO:0033628 regulation of cell adhesion mediated by integrin;GO:0006493 protein O-linked glycosylation;GO:0016266 protein O-linked glycosylation via N-acetyl-galactosamine;GO:0031589 cell-substrate adhesion;GO:0070278 extracellular matrix constituent secretion", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "Q9Y117-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9Y118-1", "uniprot_id": "DPOD3_DROME", "mass": 47046.0, "length": 431, "protein_name": "DNA polymerase delta subunit 3", "gene_name": "PolD3", "organism": "Fruit fly", "refseq_name": "DNA polymerase delta subunit 3, isoform B", "refseq_ac": "NP_001188816", "gene_names_uniprotkb": "PolD3; CG3975; DNApolD3; Pol32; rd", "gene_names_refseq": "BG:DS07295.3; BcDNA:GH08865; CG3975; Dmel\\CG3975; Pol32; PolD3; pol32; rd", "protein_names_uniprotkb": "DNA polymerase delta subunit 3; Pol32 polymerase delta subunit 3", "protein_names_refseq": "CG3975-PB; DNA polymerase delta subunit 3, isoform B; Pol32 polymerase delta subunit; PolD3-PB; reduced", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG3975)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "10731132;10731138;12537572;22532806;25826374;31053594;31100062", "class_list": "", "function": "Accessory component of the DNA polymerase delta complex and possibly the DNA polymerase zeta complex (By similarity). As a component of the delta complex, participates in high fidelity genome replication, including lagging strand synthesis, DNA recombination and repair (PubMed:22532806, PubMed:25826374, PubMed:31100062). Required to recruit the DNA polymerase delta complex to the nucleus of rapidly dividing embryonic cells, and as a consequence is essential for genome replication during the earliest cell cycles (PubMed:25826374, PubMed:31100062). Increases the efficiency and processivity of DNA synthesis of the DNA polymerases during mitotic DNA replication and repair (PubMed:22532806, PubMed:25826374, PubMed:31100062). During development this function is essential for preventing replication stress that results in the formation of chromosomal fragile sites (CFS) such as chromosomal breaks (PubMed:25826374, PubMed:31100062). Ensures genomic stability by promoting several types of DNA repair mechanisms including repairing broken dicentric chromosomes through homolog-dependent break-induced replication (BIR) (PubMed:22532806, PubMed:25826374, PubMed:31053594). During homologous recombination (HR) repair, required for maintaining the processivity of the delta complex during break-induced replication; a form of HR that requires extensive DNA synthesis such as the repair of large gaps (PubMed:22532806, PubMed:25826374). Able to suppress position effect variegation and may therefore have a role in the induction of chromatin state changes that likely include its activities in DNA replication and repair (PubMed:25826374)., [UniProtKB, PubMed, UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 8, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0030337 DNA polymerase processivity factor activity", "go_cellular_component": "GO:0043625 delta DNA polymerase complex;GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0016035 zeta DNA polymerase complex", "go_biological_process": "GO:0006281 DNA repair;GO:0000724 double-strand break repair via homologous recombination;GO:0031503 protein-containing complex localization;GO:0000727 double-strand break repair via break-induced replication;GO:0042276 error-prone translesion synthesis", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q9Y118-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9Y140-1", "uniprot_id": "DHRS7_DROME", "mass": 35744.0, "length": 326, "protein_name": "Dehydrogenase/reductase SDR family protein 7-like", "gene_name": "CG7601", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": "NP_651717", "gene_names_uniprotkb": "CG7601", "gene_names_refseq": "BcDNA:GH06026; CG7601; DHRS7B; Dmel\\CG7601", "protein_names_uniprotkb": "Dehydrogenase/reductase SDR family protein 7-like; 1.1.-.-", "protein_names_refseq": "CG7601-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG7601); (R-DME-75896)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "10731132;10731138;12537572", "class_list": "", "function": "Putative oxidoreductase., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.1.-.-", "go_molecular_function": "GO:0000140 acylglycerone-phosphate reductase (NADP+) activity", "go_cellular_component": "GO:0005778 peroxisomal membrane;GO:0016020 membrane", "go_biological_process": "GO:0006629 lipid metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9Y140-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A023GRW3-1", "uniprot_id": "A0A023GRW3_DROME", "mass": 107664.0, "length": 949, "protein_name": "RNA-binding protein 5-A", "gene_name": "Dmel\\CG4896", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform D", "refseq_ac": "NP_608583", "gene_names_uniprotkb": "Dmel\\CG4896; 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ATG9; Atg9a; CG3615; Dmel\\CG3615; Dmel_CG3615; atg9; dAtg9", "gene_names_refseq": "ATG9; Atg9a; Atg9; CG3615; Dmel\\CG3615; atg9; dAtg9", "protein_names_uniprotkb": "Autophagy-related protein 9", "protein_names_refseq": "Atg9-PB; Autophagy-related 9, isoform B; Autophagy-specific gene 9; CG3615-PB", "tax_id": 7227, "disease": "Parkinson's disease (Disease Ontology:DOID:14330)", "pathway": " (dme:Dmel_CG3615); (R-DME-1632852); (R-DME-5205685)", "pathway_count": 3, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "Phospholipid scramblase involved in autophagy. Cycles between the preautophagosomal structure/phagophore assembly site (PAS) and the cytoplasmic vesicle pool and supplies membrane for the growing autophagosome. Lipid scramblase activity plays a key role in preautophagosomal structure/phagophore assembly by distributing the phospholipids that arrive through ATG2 from the cytoplasmic to the luminal leaflet of the bilayer, thereby driving autophagosomal membrane expansion., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0017128 phospholipid scramblase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0016020 membrane;GO:0030054 cell junction;GO:0005776 autophagosome;GO:0034045 phagophore assembly site membrane", "go_biological_process": "GO:0000045 autophagosome assembly;GO:0046330 positive regulation of JNK cascade;GO:0016236 macroautophagy;GO:0006914 autophagy;GO:0034599 cellular response to oxidative stress", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0B4KF86-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0B4KFC9-1", "uniprot_id": "A0A0B4KFC9_DROME", "mass": 98662.0, "length": 881, "protein_name": "FXNA-like protease", "gene_name": "Dmel\\CG10073", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform C", "refseq_ac": "NP_001261090", "gene_names_uniprotkb": "Dmel\\CG10073; CG10073; Dmel_CG10073; FBgn0034440", "gene_names_refseq": "CG10073; Dmel\\CG10073; FBgn0034440", "protein_names_uniprotkb": "FXNA-like protease", "protein_names_refseq": "CG10073-PC; uncharacterized protein, isoform C", "tax_id": 7227, "disease": "chronic kidney disease (Disease Ontology:DOID:784)", "pathway": " (dme:Dmel_CG10073)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0046872 metal ion binding;GO:0008235 metalloexopeptidase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006508 proteolysis", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0B4KFC9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0B4KFF2-1", "uniprot_id": "A0A0B4KFF2_DROME", "mass": 53497.0, "length": 474, "protein_name": "Peptidase S1 domain-containing protein", "gene_name": "Dmel\\CG43742", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": "NP_001261130", "gene_names_uniprotkb": "Dmel\\CG43742; CG43742; Dmel_CG43742; SP251", "gene_names_refseq": "CG43742; Dmel\\CG43742; SP251", "protein_names_uniprotkb": "Peptidase S1 domain-containing protein", "protein_names_refseq": "CG43742-PB; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG43742)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004252 serine-type endopeptidase activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0006508 proteolysis;GO:0045087 innate immune response;GO:0051604 protein maturation", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0B4KFF2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0B4KFL3-1", "uniprot_id": "A0A0B4KFL3_DROME", "mass": 66877.0, "length": 605, "protein_name": "Katanin p60 ATPase-containing subunit A1", "gene_name": "Kat60", "organism": "Fruit fly", "refseq_name": "katanin 60, isoform B", "refseq_ac": "NP_001262276", "gene_names_uniprotkb": "Kat60; CG10229; Dm-Kat60; DmCG10229; Dmel\\CG10229; Dmel_CG10229; KATNA1; Kat-60; Katanin-60; kat-60; kat60; katanin-60; katanin60-dm", "gene_names_refseq": "CG10229; Dm-Kat60; DmCG10229; Dmel\\CG10229; Kat-60; Kat60; Katanin-60; kat-60; kat60; katanin-60; katanin60-dm", "protein_names_uniprotkb": "Katanin p60 ATPase-containing subunit A1; 5.6.1.1; Katanin p60 subunit A1; p60 katanin", "protein_names_refseq": "CG10229-PB; Kat60-PB; Katanin-60; katanin 60, isoform B; katanin 60; katanin", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG10229)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation., [UniProtKB, HAMAP, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008568 microtubule severing ATPase activity;GO:0005524 ATP binding;GO:0008017 microtubule binding;GO:0016887 ATP hydrolysis activity;GO:0017022 myosin binding", "go_cellular_component": "GO:0000922 spindle pole;GO:0005737 cytoplasm;GO:0005813 centrosome;GO:0005819 spindle;GO:0005938 cell cortex", "go_biological_process": "GO:0051013 microtubule severing;GO:0016358 dendrite development;GO:0051301 cell division;GO:0030336 negative regulation of cell migration;GO:0007019 microtubule depolymerization", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0B4KFL3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0B4KFQ5-1", "uniprot_id": "A0A0B4KFQ5_DROME", "mass": 36255.0, "length": 316, "protein_name": "Tetraspanin-33", "gene_name": "Tsp86D", "organism": "Fruit fly", "refseq_name": "tetraspanin 86D, isoform C", "refseq_ac": "NP_001262468", "gene_names_uniprotkb": "Tsp86D; 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3; CG8208; Dmel\\CG8208; Dmel_CG8208; MBD2-3; MBD2; MBD3; dMBD-like", "gene_names_refseq": "CG8208; Dm Mbd2/3; DmMbd2/3; Dmel\\CG8208; MBD-like; MBD2-3; MBD2/3; MBD2; MBD3; dMBD-like; dMBD2/3; dMbD2/3", "protein_names_uniprotkb": "Methyl-CpG binding domain protein-like, isoform C", "protein_names_refseq": "CG8208-PC; MBD-like-PC; Methyl-CpG binding domain protein-like, isoform C; methyl-CpG-binding-domain-like-protein", "tax_id": 7227, "disease": "transient cerebral ischemia (Disease Ontology:DOID:224); schizophrenia (Disease Ontology:DOID:5419); rheumatoid arthritis (Disease Ontology:DOID:7148); choline deficiency disease (Disease Ontology:DOID:8456); type 1 diabetes mellitus (Disease Ontology:DOID:9744)", "pathway": " (dme:Dmel_CG8208); (R-DME-3214815); (R-DME-427413); (R-DME-6804758); (R-DME-8943724); (R-DME-9937850); (R-DME-9940951)", "pathway_count": 7, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0042803 protein homodimerization activity;GO:0003714 transcription corepressor activity;GO:0042826 histone deacetylase binding;GO:0008327 methyl-CpG binding", "go_cellular_component": "GO:0005634 nucleus;GO:0016581 NuRD complex;GO:0005700 polytene chromosome", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006338 chromatin remodeling;GO:0006351 DNA-templated transcription;GO:0045892 negative regulation of DNA-templated transcription;GO:0030261 chromosome condensation", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0B4KGZ0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0B4KH03-1", "uniprot_id": "A0A0B4KH03_DROME", "mass": 31819.0, "length": 284, "protein_name": "Tetraspanin", "gene_name": "Tsp96F", "organism": "Fruit fly", "refseq_name": "tetraspanin 96F, isoform B", "refseq_ac": "NP_001262976", "gene_names_uniprotkb": "Tsp96F; 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BcDNA:GM02031; Beta-TRCP1; CG3412; Dmel\\CG3412; Dmel_CG3412; FBXW1; MENE (3R)-B; MENE(3R)-B; SLIMB; SLMB; Slimb; Slmb; beta-TRCP; beta-TrCP; betaTrCP; crd; ica; l(3)00295; shv; slimb; wel", "gene_names_refseq": "BcDNA:GM02031; CG3412; Dmel\\CG3412; FBXW1; MENE (3R)-B; MENE(3R)-B; SLIMB; SLMB; Slimb/Beta-TRCP1; Slimb/beta-TRCP; Slimb/beta-TrCP; Slimb/betaTrCP; Slimb; Slmb; beta-TrCP; betaTrCP; crd; ica; l(3)00295; shv; slimb; slmb; wel", "protein_names_uniprotkb": "Supernumerary limbs, isoform B", "protein_names_refseq": "CG3412-PB; SCF-betaTrCP complex; SLIMB; centrosome replication defective; icare; pingiel; shiva; slmb-PB; supernumerary limbs, isoform B; supernumerary limbs; wellman", "tax_id": 7227, "disease": "Menkes disease (Disease Ontology:DOID:1838)", "pathway": " (dme:Dmel_CG3412)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0046983 protein dimerization activity;GO:0051219 phosphoprotein binding;GO:1904713 beta-catenin destruction complex binding;GO:1990756 ubiquitin-like ligase-substrate adaptor activity", "go_cellular_component": "GO:0019005 SCF ubiquitin ligase complex;GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006508 proteolysis;GO:0008285 negative regulation of cell population proliferation;GO:0043066 negative regulation of apoptotic process;GO:0007623 circadian rhythm;GO:0016055 Wnt signaling pathway", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0B4KHK1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A6M3Q9L5-1", "uniprot_id": "A0A6M3Q9L5_DROME", "mass": 99021.0, "length": 891, "protein_name": "2.7.1.68; Phosphatidylinositol 4-phosphate 5-kinase 59B, isoform J", "gene_name": "PIP5K59B", "organism": "Fruit fly", "refseq_name": "phosphatidylinositol 4-phosphate 5-kinase 59B, isoform J", "refseq_ac": "NP_001369113", "gene_names_uniprotkb": "PIP5K59B; CG17281; CG3682; Dmel\\CG3682; Dmel_CG3682; PI4P5K; PIP5K 59B; PIP5K; PIPK59B; dPIP5K59B; dPIP5K; dpip5k", "gene_names_refseq": "CG17281; CG3682; Dmel\\CG3682; PI4P5K; PIP5K 59B; PIP5K59B; PIP5K; PIPK59B; dPIP5K59B; dPIP5K; dpip5k", "protein_names_uniprotkb": "2.7.1.68; Phosphatidylinositol 4-phosphate 5-kinase 59B, isoform J", "protein_names_refseq": "CG3682-PJ; PIP5K59B-PJ; phosphatidylinositol 4-phosphate 5-kinase 59B, isoform J; phosphatidylinositol 4-phosphate 5-kinase at 59B", "tax_id": 7227, "disease": "cancer (Disease Ontology:DOID:162)", "pathway": " (dme:Dmel_CG3682); (R-DME-1660499); (R-DME-201688); (R-DME-399955); (R-DME-6811558); (R-DME-8856828)", "pathway_count": 6, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.1.68", "go_molecular_function": "GO:0005524 ATP binding;GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0035997 rhabdomere microvillus membrane;GO:0005886 plasma membrane", "go_biological_process": "GO:0007603 phototransduction, visible light;GO:0010513 positive regulation of phosphatidylinositol biosynthetic process;GO:0046488 phosphatidylinositol metabolic process;GO:0071482 cellular response to light stimulus;GO:0008582 regulation of synaptic assembly at neuromuscular junction", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A6M3Q9L5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A1Z7S9-1", "uniprot_id": "A1Z7S9_DROME", "mass": 19622.0, "length": 170, "protein_name": "tRNA splicing endonuclease subunit 15, isoform A", "gene_name": "Tsen15", "organism": "Fruit fly", "refseq_name": "tRNA splicing endonuclease subunit 15, isoform A", "refseq_ac": "NP_724774", "gene_names_uniprotkb": "Tsen15; BcDNA:GM04716; CG30343; Dmel\\CG30343; Dmel_CG30343; TSEN15", "gene_names_refseq": "BcDNA:GM04716; CG30343; Dmel\\CG30343; TSEN15; Tsen15", "protein_names_uniprotkb": "tRNA splicing endonuclease subunit 15, isoform A", "protein_names_refseq": "CG30343-PA; Tsen15-PA; tRNA splicing endonuclease subunit 15, isoform A", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG30343)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003676 nucleic acid binding;GO:0004519 endonuclease activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation;GO:0008033 tRNA processing", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A1Z7S9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A1Z6P8-1", "uniprot_id": "A1Z6P8_DROME", "mass": 113842.0, "length": 1006, "protein_name": "Exchange protein directly activated by cAMP, isoform E", "gene_name": "Epac", "organism": "Fruit fly", "refseq_name": "exchange protein directly activated by cAMP, isoform E", "refseq_ac": "NP_001097202", "gene_names_uniprotkb": "Epac; CG15235; CG3427; CG34392; D-EPAC; D-Epac; Dm_2R:10367; Dmel\\CG34392; Dmel_CG34392; epac", "gene_names_refseq": "CG15235; CG3427; CG34392; D-EPAC; D-Epac; Dm_2R:10367; Dmel\\CG34392; Epac; epac", "protein_names_uniprotkb": "Exchange protein directly activated by cAMP, isoform E", "protein_names_refseq": "CG34392-PE; Epac-PE; epac guanine nucleotide exchange factor; exchange protein directly activated by cAMP ortholog; exchange protein directly activated by cAMP, isoform E", "tax_id": 7227, "disease": "nicotine dependence (Disease Ontology:DOID:0050742); autistic disorder (Disease Ontology:DOID:12849); congestive heart failure (Disease Ontology:DOID:6000)", "pathway": " (dme:Dmel_CG34392); (R-DME-354192); (R-DME-381676); (R-DME-392517); (R-DME-422356)", "pathway_count": 5, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005085 guanyl-nucleotide exchange factor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0032487 regulation of Rap protein signal transduction;GO:0007264 small GTPase-mediated signal transduction;GO:0007265 Ras protein signal transduction", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A1Z6P8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0B4KHF1-1", "uniprot_id": "A0A0B4KHF1_DROME", "mass": 60415.0, "length": 524, "protein_name": "Mitochondrial calcium uptake 3, isoform D", "gene_name": "MICU3", "organism": "Fruit fly", "refseq_name": "mitochondrial calcium uptake 3, isoform D", "refseq_ac": "NP_001262741", "gene_names_uniprotkb": "MICU3; CG4662; Dmel\\CG4662; Dmel_CG4662; micu3", "gene_names_refseq": "CG4662; Dmel\\CG4662; MICU3; micu3", "protein_names_uniprotkb": "Mitochondrial calcium uptake 3, isoform D", "protein_names_refseq": "CG4662-PD; MICU3-PD; mitochondrial calcium uptake 3, isoform D", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG4662); (R-DME-8949215); (R-DME-8949664)", "pathway_count": 3, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005509 calcium ion binding;GO:0005246 calcium channel regulator activity", "go_cellular_component": "GO:0005743 mitochondrial inner membrane;GO:0005758 mitochondrial intermembrane space;GO:1990246 uniplex complex", "go_biological_process": "GO:0036444 calcium import into the mitochondrion;GO:0051560 mitochondrial calcium ion homeostasis", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0B4KHF1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0B4KI51-1", "uniprot_id": "A0A0B4KI51_DROME", "mass": 322066.0, "length": 3003, "protein_name": "BRD4 interacting chromatin remodeling complex associated protein, isoform B", "gene_name": "Bicra", "organism": "Fruit fly", "refseq_name": "BRD4 interacting chromatin remodeling complex associated protein, isoform B", "refseq_ac": "NP_001263051", "gene_names_uniprotkb": "Bicra; CG11873; Dmel\\CG11873; Dmel_CG11873; anon-WO0140519.162", "gene_names_refseq": "Bicra; CG11873; Dmel\\CG11873; anon-WO0140519.162", "protein_names_uniprotkb": "BRD4 interacting chromatin remodeling complex associated protein, isoform B", "protein_names_refseq": "BRD4 interacting chromatin remodeling complex associated protein, isoform B; Bicra-PB; CG11873-PB", "tax_id": 7227, "disease": "Coffin-Siris syndrome 12 (Disease Ontology:DOID:0112370); Coffin-Siris syndrome (Disease Ontology:DOID:1925)", "pathway": " (dme:Dmel_CG11873); (R-DME-9933947)", "pathway_count": 2, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 11, "predicted_n_glycosites": 0, "predicted_o_glycosites": 11, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 11, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0016514 SWI/SNF complex;GO:0035060 brahma complex", "go_biological_process": "GO:0034976 response to endoplasmic reticulum stress;GO:0006338 chromatin remodeling;GO:0045893 positive regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0B4KI51-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0B4LF16-1", "uniprot_id": "A0A0B4LF16_DROME", "mass": 51574.0, "length": 452, "protein_name": "Palmitoyltransferase", "gene_name": "Dmel\\CG1407", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform G", "refseq_ac": "NP_001286264", "gene_names_uniprotkb": "Dmel\\CG1407; CG1407; Dmel_CG1407; ZDHHC15", "gene_names_refseq": "CG1407; Dmel\\CG1407; ZDHHC15", "protein_names_uniprotkb": "Palmitoyltransferase; 2.3.1.225", "protein_names_refseq": "CG1407-PG; uncharacterized protein, isoform G", "tax_id": 7227, "disease": "syndrome (Disease Ontology:DOID:225)", "pathway": " (dme:Dmel_CG1407)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.3.1.225", "go_molecular_function": "GO:0019706 protein-cysteine S-palmitoyltransferase activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus", "go_biological_process": "GO:0006612 protein targeting to membrane;GO:0016188 synaptic vesicle maturation", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0B4LF16-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A1ZBW6-1", "uniprot_id": "A1ZBW6_DROME", "mass": 82630.0, "length": 726, "protein_name": "G-patch domain-containing protein", "gene_name": "Dmel\\CG11180", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform A", "refseq_ac": "NP_611495", "gene_names_uniprotkb": "Dmel\\CG11180; CG11180; Dmel_CG11180", "gene_names_refseq": "CG11180; Dmel\\CG11180", "protein_names_uniprotkb": "G-patch domain-containing protein", "protein_names_refseq": "CG11180-PA; uncharacterized protein, isoform A", "tax_id": 7227, "disease": "cancer (Disease Ontology:DOID:162); hepatocellular carcinoma (Disease Ontology:DOID:684)", "pathway": " (dme:Dmel_CG11180)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003676 nucleic acid binding;GO:0010521 telomerase inhibitor activity", "go_cellular_component": "GO:0005730 nucleolus", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A1ZBW6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "E1JIH3-1", "uniprot_id": "E1JIH3_DROME", "mass": 93910.0, "length": 844, "protein_name": "Uncoordinated 115a, isoform B", "gene_name": "Unc-115a", "organism": "Fruit fly", "refseq_name": "uncoordinated 115a, isoform B", "refseq_ac": "NP_001163573", "gene_names_uniprotkb": "Unc-115a; CG31352; CG9489; Dmel\\CG31352; Dmel_CG31352; Dunc-115; Unc-115b; anon-WO0140519.21; dunc-115; unc-115; unc-15a", "gene_names_refseq": "CG31352; CG9489; Dmel\\CG31352; Dunc-115; Unc-115a; anon-WO0140519.21; dunc-115; unc-115; unc-15a", "protein_names_uniprotkb": "Uncoordinated 115a, isoform B", "protein_names_refseq": "CG31352-PB; Unc-115a-PB; uncoordinated 115a, isoform B", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG31352); (R-DME-5223345)", "pathway_count": 2, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003779 actin binding;GO:0046872 metal ion binding;GO:0051015 actin filament binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0015629 actin cytoskeleton;GO:0005654 nucleoplasm", "go_biological_process": "GO:0007010 cytoskeleton organization;GO:0007411 axon guidance;GO:0072499 photoreceptor cell axon guidance;GO:0030032 lamellipodium assembly", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "E1JIH3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "M9MRJ1-1", "uniprot_id": "M9MRJ1_DROME", "mass": 104194.0, "length": 984, "protein_name": "Uncharacterized protein", "gene_name": "CG16851; CG31846; CR31846; mdcds_2231", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform F", "refseq_ac": "NP_001188798", "gene_names_uniprotkb": "CG16851; CG31846; CR31846; mdcds_2231; BcDNA:GH04046; BcDNA:HL01958; CG16850; CG16851; CG31846; CG31847; CG42784; CR31846; Dm_2L:67149; Dmel\\CG42784; Dmel_CG42784; mdcds_2231", "gene_names_refseq": "BcDNA:GH04046; BcDNA:HL01958; CG16850; CG16851; CG31846; CG31847; CG42784; CR31846; Dm_2L:67149; Dmel\\CG42784; mdcds_2231", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "CG42784-PF; uncharacterized protein, isoform F", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG42784)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0080008 Cul4-RING E3 ubiquitin ligase complex", "go_biological_process": "GO:0016567 protein ubiquitination", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "M9MRJ1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "M9NEB2-1", "uniprot_id": "M9NEB2_DROME", "mass": 137409.0, "length": 1273, "protein_name": "Protein phosphatase 1 regulatory subunit 12B", "gene_name": "Mbs", "organism": "Fruit fly", "refseq_name": "myosin binding subunit, isoform O", "refseq_ac": "NP_001246786", "gene_names_uniprotkb": "Mbs; 04; 06; CG32156; CG5600; CG5891; DMBS; DMYPT; DMbs; Dmel\\CG32156; Dmel_CG32156; MBS; Mypt; l(3)03802; l(3)72Dd; l(3)S005331b; l(3)S057306b; l(3)S057306; l(3)S095304; l(3)j3B4; l(3)j7A1; mbs", "gene_names_refseq": "0573/06; 0953/04; CG32156; CG5600; CG5891; DMBS; DMYPT; DMbs; Dmel\\CG32156; MBS; Mbs; Mypt; l(3)03802; l(3)72Dd; l(3)S005331b; l(3)S057306b; l(3)S057306; l(3)S095304; l(3)j3B4; l(3)j7A1; mbs", "protein_names_uniprotkb": "Protein phosphatase 1 regulatory subunit 12B; Myosin phosphatase-targeting subunit 2", "protein_names_refseq": "CG32156-PO; MLC-phosphatase; Mbs-PO; lethal (3) S057306b; lethal (3) S095304; lethal(3)72Dd; myosin binding subunit, isoform O; myosin binding subunit; myosin phosphatase target subunit; myosin phosphatase-binding subunit; myosin-binding subunit", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG32156); (R-DME-2565942); (R-DME-350416); (R-DME-350480); (R-DME-5625740); (R-DME-5627123)", "pathway_count": 6, "publication_count": 15, "publication_id_list": "10570971;10731132;11301004;11874917;12537568;12537572;12537573;12537574;15269282;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "Regulates myosin phosphatase activity. Augments Ca(2+) sensitivity of the contractile apparatus., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 4, "predicted_n_glycosites": 0, "predicted_o_glycosites": 4, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0019901 protein kinase binding;GO:0017020 myosin phosphatase regulator activity;GO:0004857 enzyme inhibitor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005856 cytoskeleton;GO:0045179 apical cortex;GO:0045177 apical part of cell;GO:0005829 cytosol", "go_biological_process": "GO:1904059 regulation of locomotor rhythm;GO:0008544 epidermis development;GO:0048812 neuron projection morphogenesis;GO:0030725 germline ring canal formation;GO:0007391 dorsal closure", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "M9NEB2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A6M3Q7H0-1", "uniprot_id": "A0A6M3Q7H0_DROME", "mass": 125656.0, "length": 1170, "protein_name": "Pipsqueak, isoform O", "gene_name": "psq", "organism": "Fruit fly", "refseq_name": "pipsqueak, isoform O", "refseq_ac": "NP_001369078", "gene_names_uniprotkb": "psq; BTB-V; BtbV; CG2368; Dmel\\CG2368; Dmel_CG2368; Lola; PSQ; Pipsqueak; Piq; Psq; eyeful; pip; psk; psq-1; rum; zep", "gene_names_refseq": "BTB-V; BtbV; CG2368; Dmel\\CG2368; Lola; PSQ; Pipsqueak; Piq; Psq; eyeful; pip; psk; psq-1; psq; rum; zep", "protein_names_uniprotkb": "Pipsqueak, isoform O", "protein_names_refseq": "BTB-protein-V; CG2368-PO; eyeful; peepsqueak; pipsqeak; pipsqueak, isoform O; pipsqueak; psq-PO; rumpf; zeppelin; zepplin", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG2368)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0042803 protein homodimerization activity;GO:0043565 sequence-specific DNA binding;GO:0031208 POZ domain binding", "go_cellular_component": "GO:0005634 nucleus;GO:0031519 PcG protein complex", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0031507 heterochromatin formation;GO:0009880 embryonic pattern specification;GO:0008595 anterior/posterior axis specification, embryo;GO:0007315 pole plasm assembly", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A6M3Q7H0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A1Z6Z8-1", "uniprot_id": "A1Z6Z8_DROME", "mass": 208245.0, "length": 1800, "protein_name": "5.6.1.8; Dilute class unconventional myosin, isoform C", "gene_name": "didum", "organism": "Fruit fly", "refseq_name": "dilute class unconventional myosin, isoform C", "refseq_ac": "NP_724569", "gene_names_uniprotkb": "didum; 43CD; CG2146; Didum; DmV; Dmel\\CG2146; Dmel_CG2146; M5; MYOV; Myo1C; Myo5; MyoV43CD; MyoV; NEST:bs14c05; NMC7; dmM5; myoV; soy", "gene_names_refseq": "43CD; CG2146; Didum; DmV; Dmel\\CG2146; M5; MYOV; Myo1C; Myo5; MyoV43CD; MyoV; NEST:bs14c05; NMC7; didum; dmM5; myoV; soy", "protein_names_uniprotkb": "5.6.1.8; Dilute class unconventional myosin, isoform C", "protein_names_refseq": "CG2146-PC; Myosin5; MyosinV; didum-PC; dilute class unconventional myosin, isoform C; myosin V; myosin-5; myosin-V; shorty", "tax_id": 7227, "disease": "microvillus inclusion disease (Disease Ontology:DOID:0060775); Griscelli syndrome type 1 (Disease Ontology:DOID:0060832); progressive familial intrahepatic cholestasis (Disease Ontology:DOID:0070221)", "pathway": " (dme:Dmel_CG2146); (R-DME-432040)", "pathway_count": 2, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "5.6.1.8", "go_molecular_function": "GO:0003779 actin binding;GO:0005516 calmodulin binding;GO:0005524 ATP binding;GO:0032027 myosin light chain binding;GO:0030899 calcium-dependent ATPase activity", "go_cellular_component": "GO:0031475 myosin V complex;GO:0005737 cytoplasm;GO:0043025 neuronal cell body;GO:0016459 myosin complex;GO:0016028 rhabdomere", "go_biological_process": "GO:0047497 mitochondrion transport along microtubule;GO:0006886 intracellular protein transport;GO:0030048 actin filament-based movement;GO:0009888 tissue development;GO:0007291 sperm individualization", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A1Z6Z8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A8DYB7-1", "uniprot_id": "A8DYB7_DROME", "mass": 90485.0, "length": 816, "protein_name": "Dystrobrevin, isoform F", "gene_name": "Dyb", "organism": "Fruit fly", "refseq_name": "dystrobrevin, isoform F", "refseq_ac": "NP_001097287", "gene_names_uniprotkb": "Dyb; CG8529; DmDYB; Dmel\\CG8529; Dmel_CG8529", "gene_names_refseq": "CG8529; DmDYB; Dmel\\CG8529; Dyb", "protein_names_uniprotkb": "Dystrobrevin, isoform F", "protein_names_refseq": "CG8529-PF; Dyb-PF; Dystrobrevin-like; dystrobrevin, isoform F", "tax_id": 7227, "disease": "cardiomyopathy (Disease Ontology:DOID:0050700); left ventricular noncompaction (Disease Ontology:DOID:0060480); myopathy with myalgia, increased serum creatine kinase, and with or without episodic rhabdomyolysis 2 (Disease Ontology:DOID:0061184); Duchenne muscular dystrophy (Disease Ontology:DOID:11723)", "pathway": " (dme:Dmel_CG8529); (R-DME-9913351)", "pathway_count": 2, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0008307 structural constituent of muscle", "go_cellular_component": "GO:0016010 dystrophin-associated glycoprotein complex;GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0031594 neuromuscular junction;GO:0045202 synapse", "go_biological_process": "GO:0046716 muscle cell cellular homeostasis;GO:0050804 modulation of chemical synaptic transmission;GO:0048790 maintenance of presynaptic active zone structure;GO:0046928 regulation of neurotransmitter secretion;GO:0099536 synaptic signaling", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A8DYB7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "B7YZT5-1", "uniprot_id": "B7YZT5_DROME", "mass": 155371.0, "length": 1364, "protein_name": "Phospholipase", "gene_name": "Pld", "organism": "Fruit fly", "refseq_name": "phospholipase D, isoform F", "refseq_ac": "NP_001137610", "gene_names_uniprotkb": "Pld; CG12110; Dmel\\CG12110; Dmel_CG12110; MitoPLD; PC-Pld; PLD; dPLD; dPld; phospholipase D; pld1; pld", "gene_names_refseq": "CG12110; Dmel\\CG12110; MitoPLD; PC-Pld; PLD; Pld; dPLD; dPld; phospholipase D; pld1; pld", "protein_names_uniprotkb": "Phospholipase; 3.1.4.4", "protein_names_refseq": "CG12110-PF; Phosphatidylcholine-specific phospholipase-D; Pld-PF; phospholipase D, isoform F; phospholipase D", "tax_id": 7227, "disease": "developmental cardiac valvular defect (Disease Ontology:DOID:0080633); pancreatic ductal adenocarcinoma (Disease Ontology:DOID:3498); renal cell carcinoma (Disease Ontology:DOID:4450); congestive heart failure (Disease Ontology:DOID:6000)", "pathway": " (dme:Dmel_CG12110); (R-DME-1483166); (R-DME-2029485); (R-DME-6798695); (R-DME-8980692); (R-DME-9013149)", "pathway_count": 6, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.11.1;1.2.1.-;1.2.1.3;1.-.-.-;2.7.11.13;7.6.2.1;3.4.24.-;3.1.4.4;6.2.1.3;3.6.5.2;2.7.10.2;1.14.19.17;2.7.10.1;3.4.24.81;2.3.1.51;3.1.3.48;2.3.1.78", "go_molecular_function": "GO:0004630 phospholipase D activity;GO:0035091 phosphatidylinositol binding", "go_cellular_component": "GO:0012505 endomembrane system;GO:0031410 cytoplasmic vesicle;GO:0005886 plasma membrane", "go_biological_process": "GO:0006654 phosphatidic acid biosynthetic process;GO:0035556 intracellular signal transduction;GO:0016042 lipid catabolic process;GO:0007030 Golgi organization;GO:0007602 phototransduction", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "B7YZT5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "M9MRX4-1", "uniprot_id": "M9MRX4_DROME", "mass": 1488354.0, "length": 13559, "protein_name": "Ankyrin 2, isoform U", "gene_name": "Ank2", "organism": "Fruit fly", "refseq_name": "ankyrin 2, isoform U", "refseq_ac": "NP_001189070", "gene_names_uniprotkb": "Ank2; CG18025; CG18227; CG18768; CG32373; CG32375; CG32377; CG34121; CG34158; CG34416; CG42734; CG7462; CG7493; DAnk2; Dank2; Dmel\\CG42734; Dmel_CG42734; ESTS:149B10S; SP2523; ank2-L; ank2; dank2; sp2523", "gene_names_refseq": "Ank2; CG18025; CG18227; CG18768; CG32373; CG32375; CG32377; CG34121; CG34158; CG34416; CG42734; CG7462; CG7493; DAnk2; Dank2; Dmel\\CG42734; ESTS:149B10S; SP2523; ank2-L; ank2; dank2; sp2523", "protein_names_uniprotkb": "Ankyrin 2, isoform U", "protein_names_refseq": "Ank2-PU; Ankyrin2 extra large; CG42734-PU; Dank2; SP2523; ankyrin 2, isoform U; ankyrin2-XL", "tax_id": 7227, "disease": "sinoatrial node disease (Disease Ontology:DOID:0050824); atrial fibrillation (Disease Ontology:DOID:0060224); ankyrin-B-related cardiac arrhythmia (Disease Ontology:DOID:0111700); intellectual disability (Disease Ontology:DOID:1059); Alzheimer's disease (Disease Ontology:DOID:10652); autistic disorder (Disease Ontology:DOID:12849); sick sinus syndrome (Disease Ontology:DOID:13884); status epilepticus (Disease Ontology:DOID:1824); epilepsy (Disease Ontology:DOID:1826); transient cerebral ischemia (Disease Ontology:DOID:224); long QT syndrome (Disease Ontology:DOID:2843)", "pathway": " (R-DME-8951664); (R-DME-983168)", "pathway_count": 2, "publication_count": 17, "publication_id_list": "10731132;11329;11334;12185;12451;12537568;12537572;12537573;12537574;13414;16110336;17569856;17569867;25589440;26109356;26109357;40245499", "class_list": "", "function": "", "predicted_glycosites": 4, "predicted_n_glycosites": 0, "predicted_o_glycosites": 4, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 6, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 6, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 6, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 11, "glyco_site_count": 10, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005856 cytoskeleton;GO:0005886 plasma membrane;GO:0031594 neuromuscular junction;GO:0043195 terminal bouton;GO:0042734 presynaptic membrane", "go_biological_process": "GO:0007165 signal transduction;GO:0007528 neuromuscular junction development;GO:0070050 neuron cellular homeostasis;GO:0007614 short-term memory;GO:0007605 sensory perception of sound", "synthesized_glycan_count": 0, "hit_score": 2.5, "record_id": "M9MRX4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A1Z8G0-1", "uniprot_id": "A1Z8G0_DROME", "mass": 66674.0, "length": 595, "protein_name": "Menage a trois, isoform A", "gene_name": "metro", "organism": "Fruit fly", "refseq_name": "menage a trois, isoform A", "refseq_ac": "NP_610642", "gene_names_uniprotkb": "metro; CG13219; CG18338; CG30021; Dmel\\CG30021; Dmel_CG30021; FBgn0050021; Metro; met", "gene_names_refseq": "CG13219; CG18338; CG30021; Dmel\\CG30021; FBgn0050021; Metro; metro; met", "protein_names_uniprotkb": "Menage a trois, isoform A", "protein_names_refseq": "CG30021-PA; menage a trois, isoform A; menage a trois; metro-PA", "tax_id": 7227, "disease": "", "pathway": " (R-DME-9013149); (R-DME-9013406); (R-DME-9013423)", "pathway_count": 3, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0016020 membrane;GO:0071212 subsynaptic reticulum;GO:0070161 anchoring junction;GO:0005886 plasma membrane;GO:0005911 cell-cell junction", "go_biological_process": "GO:0008582 regulation of synaptic assembly at neuromuscular junction", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A1Z8G0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "B7Z0E5-1", "uniprot_id": "B7Z0E5_DROME", "mass": 188661.0, "length": 1647, "protein_name": "Misfire, isoform F", "gene_name": "mfr", "organism": "Fruit fly", "refseq_name": "misfire, isoform F", "refseq_ac": "NP_001137919", "gene_names_uniprotkb": "mfr; 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CG17816; Dmel_CG17816", "gene_names_refseq": "CG17816; Dmel\\CG17816", "protein_names_uniprotkb": "Nuclear protein MDM1", "protein_names_refseq": "CG17816-PG; uncharacterized protein, isoform G", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG17816)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "Microtubule-binding protein that negatively regulates centriole duplication. 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CG13685; Dmel_CG13685", "gene_names_refseq": "CG13685; Dmel\\CG13685", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "CG13685-PD; uncharacterized protein, isoform D", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG13685)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0S0WPM5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0B4KHJ0-1", "uniprot_id": "A0A0B4KHJ0_DROME", "mass": 101468.0, "length": 907, "protein_name": "Grik, isoform C", "gene_name": "Grik", "organism": "Fruit fly", "refseq_name": "grik, isoform C", "refseq_ac": "NP_001262788", "gene_names_uniprotkb": "Grik; CG5621; CT17756; DKaiRIC; DmelCG5621; Dmel\\CG5621; Dmel_CG5621; KaiR1C; anon-WO0138359.5", "gene_names_refseq": "CG5621; CT17756; DKaiRIC; DmelCG5621; Dmel\\CG5621; Grik; KaiR1C; anon-WO0138359.5", "protein_names_uniprotkb": "Grik, isoform C", "protein_names_refseq": "CG5621-PC; Grik-PC; grik, isoform C", "tax_id": 7227, "disease": "autosomal recessive intellectual developmental disorder 6 (Disease Ontology:DOID:0081182); Huntington's disease (Disease Ontology:DOID:12858); childhood absence epilepsy (Disease Ontology:DOID:1825); chronic obstructive pulmonary disease (Disease Ontology:DOID:3083); temporal lobe epilepsy (Disease Ontology:DOID:3328)", "pathway": " (dme:Dmel_CG5621); (R-DME-451307); (R-DME-451308); (R-DME-500657)", "pathway_count": 4, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 5, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0015277 kainate selective glutamate receptor activity;GO:1904315 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential;GO:0008066 glutamate receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0045211 postsynaptic membrane;GO:0098839 postsynaptic density membrane", "go_biological_process": "GO:0060025 regulation of synaptic activity;GO:0035249 synaptic transmission, glutamatergic;GO:0050804 modulation of chemical synaptic transmission", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0B4KHJ0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "H9XVP2-1", "uniprot_id": "H9XVP2_DROME", "mass": 360416.0, "length": 3186, "protein_name": "Unc-13, isoform E", "gene_name": "unc-13", "organism": "Fruit fly", "refseq_name": "unc-13, isoform E", "refseq_ac": "NP_001245427", "gene_names_uniprotkb": "unc-13; CG2999; DUNC-13; Dmel\\CG2999; Dmel_CG2999; Dunc-13; Dunc13; Munc-13; UNC-13-B; UNC-13; UNC13A; UNC13B; Unc-13; Unc13A; Unc13B; Unc13; dUNC-13; dUnc-13; drunc13; dunc-13; l(4)ry16; unc13A; unc", "gene_names_refseq": "CG2999; DUNC-13; Dmel\\CG2999; Dunc-13; Dunc13; Munc-13/UNC-13; Munc-13; UNC-13-B; UNC-13; UNC13A; UNC13B; Unc-13; Unc13A; Unc13B; Unc13; dUNC-13; dUnc-13; drunc13; dunc-13; l(4)ry16; unc-13; unc13A; unc", "protein_names_uniprotkb": "Unc-13, isoform E", "protein_names_refseq": "CG2999-PE; lethal (4) ry16; unc-13, isoform E; unc-13-PE; uncoordinated-13", "tax_id": 7227, "disease": "alcohol use disorder (Disease Ontology:DOID:1574); epilepsy (Disease Ontology:DOID:1826); amyotrophic lateral sclerosis (Disease Ontology:DOID:332)", "pathway": " (dme:Dmel_CG2999); (R-DME-181429); (R-DME-181430); (R-DME-210500); (R-DME-212676); (R-DME-264642)", "pathway_count": 6, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005516 calmodulin binding;GO:0005543 phospholipid binding;GO:0008270 zinc ion binding;GO:0005509 calcium ion binding;GO:0019992 diacylglycerol binding", "go_cellular_component": "GO:0043195 terminal bouton;GO:0045211 postsynaptic membrane;GO:0005886 plasma membrane;GO:0031594 neuromuscular junction;GO:0048786 presynaptic active zone", "go_biological_process": "GO:0007268 chemical synaptic transmission;GO:0016079 synaptic vesicle exocytosis;GO:0035249 synaptic transmission, glutamatergic;GO:0007269 neurotransmitter secretion;GO:0016082 synaptic vesicle priming", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "H9XVP2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A6H2EF03-1", "uniprot_id": "A0A6H2EF03_DROME", "mass": 44708.0, "length": 397, "protein_name": "Membrane-associated protein", "gene_name": "Dmel\\CG5768", "organism": "Fruit fly", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Dmel\\CG5768; CG5768; Dmel_CG5768", "gene_names_refseq": "", "protein_names_uniprotkb": "Membrane-associated protein", "protein_names_refseq": "", "tax_id": 7227, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A6H2EF03-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0B4KHD0-1", "uniprot_id": "A0A0B4KHD0_DROME", "mass": 80023.0, "length": 740, "protein_name": "Alpha2-adrenergic-like octopamine receptor, isoform B", "gene_name": "Octalpha2R", "organism": "Fruit fly", "refseq_name": "alpha2-adrenergic-like octopamine receptor, isoform B", "refseq_ac": "NP_001262715", "gene_names_uniprotkb": "Octalpha2R; CG18208; DmOctalpha2R; Dmel\\CG18208; Dmel_CG18208; Octalpha", "gene_names_refseq": "CG18208; DmOctalpha2R; Dmel\\CG18208; Octalpha2R; Octalpha", "protein_names_uniprotkb": "Alpha2-adrenergic-like octopamine receptor, isoform B", "protein_names_refseq": "CG18208-PB; Octalpha2R-PB; alpha2-adrenergic-like octopamine receptor, isoform B; octopamine receptor", "tax_id": 7227, "disease": "familial partial lipodystrophy (Disease Ontology:DOID:0050440); alcohol dependence (Disease Ontology:DOID:0050741); nicotine dependence (Disease Ontology:DOID:0050742); metabolic dysfunction and alcohol associated liver disease (Disease Ontology:DOID:0070508); metabolic dysfunction-associated steatohepatitis (Disease Ontology:DOID:0080547); hypertension (Disease Ontology:DOID:10763); attention deficit hyperactivity disorder (Disease Ontology:DOID:1094); depressive disorder (Disease Ontology:DOID:1596); anxiety disorder (Disease Ontology:DOID:2030); morphine dependence (Disease Ontology:DOID:2560); substance abuse (Disease Ontology:DOID:302); myocardial infarction (Disease Ontology:DOID:5844); congestive heart failure (Disease Ontology:DOID:6000); type 2 diabetes mellitus (Disease Ontology:DOID:9352); diabetic neuropathy (Disease Ontology:DOID:9743); obesity (Disease Ontology:DOID:9970)", "pathway": " (dme:Dmel_CG18208); (R-DME-390696); (R-DME-392023); (R-DME-400042); (R-DME-418594); (R-DME-418597)", "pathway_count": 6, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 16, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0032795 heterotrimeric G-protein binding;GO:0008227 G protein-coupled amine receptor activity;GO:0004989 octopamine receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway;GO:0007193 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0B4KHD0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0B4KH20-1", "uniprot_id": "A0A0B4KH20_DROME", "mass": 85245.0, "length": 775, "protein_name": "Nervous fingers 2, isoform B", "gene_name": "nerfin-2", "organism": "Fruit fly", "refseq_name": "nervous fingers 2, isoform B", "refseq_ac": "NP_001262446", "gene_names_uniprotkb": "nerfin-2; CG12809; Dmel\\CG12809; Dmel_CG12809; Nerfin", "gene_names_refseq": "CG12809; Dmel\\CG12809; Nerfin; nerfin-2", "protein_names_uniprotkb": "Nervous fingers 2, isoform B", "protein_names_refseq": "CG12809-PB; nerfin-2-PB; nervous fingers 2, isoform B; nervous fingers", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG12809)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0008270 zinc ion binding;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0017053 transcription repressor complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0030154 cell differentiation;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0030182 neuron differentiation;GO:0010564 regulation of cell cycle process", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0B4KH20-1", "record_type": "protein" }, { "uniprot_canonical_ac": "B7YZX6-1", "uniprot_id": "B7YZX6_DROME", "mass": 153643.0, "length": 1406, "protein_name": "Round spermatid basic protein 1-like protein", "gene_name": "Dmel\\CG10600", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform B", "refseq_ac": "NP_001137839", "gene_names_uniprotkb": "Dmel\\CG10600; CG10600; Dmel_CG10600", "gene_names_refseq": "CG10600; Dmel\\CG10600", "protein_names_uniprotkb": "Round spermatid basic protein 1-like protein", "protein_names_refseq": "CG10600-PB; uncharacterized protein, isoform B", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG10600)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0035575 histone H4K20 demethylase activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "B7YZX6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A6H2EJG3-1", "uniprot_id": "A0A6H2EJG3_DROME", "mass": 466027.0, "length": 4065, "protein_name": "Dynein axonemal heavy chain 7", "gene_name": "Dhc36C", "organism": "Fruit fly", "refseq_name": "dynein heavy chain at 36C, isoform C", "refseq_ac": "NP_001369131", "gene_names_uniprotkb": "Dhc36C; CG5526; DHC7A; DHC; Dhc 36C; Dhc36c; Dhc; Dmel\\CG5526; Dmel_CG5526; dhc", "gene_names_refseq": "CG5526; DHC7A; DHC; Dhc 36C; Dhc36C; Dhc36c; Dhc; Dmel\\CG5526; dhc", "protein_names_uniprotkb": "Dynein axonemal heavy chain 7; Axonemal beta dynein heavy chain 7; Ciliary dynein heavy chain 7", "protein_names_refseq": "CG5526-PC; Dhc36C-PC; dynein heavy chain at 36C, isoform C; dynein-related heavy chain polypeptide", "tax_id": 7227, "disease": "primary ciliary dyskinesia (Disease Ontology:DOID:9562)", "pathway": " (dme:Dmel_CG5526)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 4, "predicted_n_glycosites": 0, "predicted_o_glycosites": 4, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0008569 minus-end-directed microtubule motor activity;GO:0051959 dynein light intermediate chain binding;GO:0045505 dynein intermediate chain binding", "go_cellular_component": "GO:0005874 microtubule;GO:0031514 motile cilium;GO:0005858 axonemal dynein complex;GO:0036126 sperm flagellum;GO:0036156 inner dynein arm", "go_biological_process": "GO:0003341 cilium movement;GO:0060294 cilium movement involved in cell motility;GO:0030317 flagellated sperm motility;GO:0007605 sensory perception of sound", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A6H2EJG3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "E1JI40-1", "uniprot_id": "E1JI40_DROME", "mass": 63092.0, "length": 555, "protein_name": "Vermiform, isoform I", "gene_name": "verm", "organism": "Fruit fly", "refseq_name": "vermiform, isoform I", "refseq_ac": "NP_001163469", "gene_names_uniprotkb": "verm; CG8756; DmCDA2; Dmel\\CG8756; Dmel_CG8756; LCBP1; N63; Verm; hlm; l(3)76BDx", "gene_names_refseq": "CG8756; DmCDA2; Dmel\\CG8756; LCBP1; N63; Verm; hlm; l(3)76BDx; verm", "protein_names_uniprotkb": "Vermiform, isoform I", "protein_names_refseq": "CG8756-PI; LDLa domain containing chitin binding protein 1; LDLa domain containing chitin binding protein-1; helmsman; verm-PI; vermiform, isoform I; vermiform", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG8756)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357;28604694", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 2, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 2, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 2, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0016787 hydrolase activity;GO:0008061 chitin binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0009986 cell surface;GO:0062129 chitin-based extracellular matrix", "go_biological_process": "GO:0060439 trachea morphogenesis;GO:0005975 carbohydrate metabolic process;GO:0007632 visual behavior;GO:0007424 open tracheal system development;GO:0035001 dorsal trunk growth, open tracheal system", "synthesized_glycan_count": 0, "hit_score": 1.6, "record_id": "E1JI40-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0C4DHC8-1", "uniprot_id": "A0A0C4DHC8_DROME", "mass": 63039.0, "length": 564, "protein_name": "1.-.-.-; 1.2.1.-; 1.2.1.3; Aldehyde dehydrogenase type III, isoform Q", "gene_name": "Aldh-III", "organism": "Fruit fly", "refseq_name": "aldehyde dehydrogenase type III, isoform Q", "refseq_ac": "NP_724562", "gene_names_uniprotkb": "Aldh-III; ALDH-III; ALDH; AldhIII; CG11140; CT41571; Dhap; Dmel\\CG11140; Dmel_CG11140; FALDH; l(2)03610", "gene_names_refseq": "ALDH-III; ALDH; Aldh-III; AldhIII; CG11140; CT41571; Dhap; Dmel\\CG11140; FALDH; l(2)03610", "protein_names_uniprotkb": "1.-.-.-; 1.2.1.-; 1.2.1.3; Aldehyde dehydrogenase type III, isoform Q", "protein_names_refseq": "Aldh-III-PQ; CG11140-PQ; aldehyde dehydrogenase type III, isoform Q; fatty aldehyde dehydrogenase", "tax_id": 7227, "disease": "Sjogren-Larsson syndrome (Disease Ontology:DOID:14501); arteriosclerosis (Disease Ontology:DOID:2349)", "pathway": " (dme:Dmel_CG11140); (R-DME-211945); (R-DME-389599); (R-DME-6798695); (R-DME-9603798); (R-DME-9609523); (R-DME-9845614)", "pathway_count": 7, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.2.1.-;1.2.1.3;1.-.-.-;7.6.2.1;3.4.24.-;3.1.4.4;6.2.1.3;3.6.5.2;3.1.3.48;7.6.2.4;3.4.11.-;1.14.19.17;2.3.2.23;3.4.24.81;2.3.1.51;2.7.11.1;2.3.1.78;3.4.24.11", "go_molecular_function": "GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor;GO:0004029 aldehyde dehydrogenase (NAD+) activity;GO:0120553 farnesal dehydrogenase (NAD+) activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005741 mitochondrial outer membrane;GO:0016020 membrane", "go_biological_process": "GO:0006081 aldehyde metabolic process", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0C4DHC8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A8DYA3-1", "uniprot_id": "A8DYA3_DROME", "mass": 336605.0, "length": 3131, "protein_name": "Toutatis, isoform E", "gene_name": "tou", "organism": "Fruit fly", "refseq_name": "toutatis, isoform E", "refseq_ac": "NP_001097270", "gene_names_uniprotkb": "tou; CG10897; Dm Tou; Dmel\\CG10897; Dmel_CG10897; EP(2)0622; EP0622; EP622; TIP5; TOU; Tou; VI; anon-48Ad; gene VI", "gene_names_refseq": "CG10897; Dm Tou; Dmel\\CG10897; EP(2)0622; EP0622; EP622; TIP5; TOU; Tou; VI; anon-48Ad; gene VI; tou", "protein_names_uniprotkb": "Toutatis, isoform E", "protein_names_refseq": "CG10897-PE; tou-PE; toutatis, isoform E; toutatis; transcript group VI", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG10897)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357;40245499", "class_list": "", "function": "", "predicted_glycosites": 4, "predicted_n_glycosites": 0, "predicted_o_glycosites": 4, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 5, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 5, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 5, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 9, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0140297 DNA-binding transcription factor binding", "go_cellular_component": "GO:0031010 ISWI-type complex;GO:0000785 chromatin", "go_biological_process": "GO:0006338 chromatin remodeling;GO:0006351 DNA-templated transcription;GO:0007399 nervous system development;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:2001208 negative regulation of transcription elongation by RNA polymerase I", "synthesized_glycan_count": 0, "hit_score": 1.9, "record_id": "A8DYA3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "B9A0M5-1", "uniprot_id": "B9A0M5_DROME", "mass": 15281.0, "length": 133, "protein_name": "Chibby, isoform E", "gene_name": "Cby", "organism": "Fruit fly", "refseq_name": "chibby, isoform E", "refseq_ac": "NP_650989", "gene_names_uniprotkb": "Cby; CBY; CG13415; Dmel\\CG13415; Dmel_CG13415; cby", "gene_names_refseq": "CBY; CG13415; Cby; Dmel\\CG13415; cby", "protein_names_uniprotkb": "Chibby, isoform E", "protein_names_refseq": "CG13415-PE; Cby-PE; chibby, isoform E; chibby", "tax_id": 7227, "disease": "otitis media (Disease Ontology:DOID:10754); primary ciliary dyskinesia (Disease Ontology:DOID:9562)", "pathway": " (dme:Dmel_CG13415); (R-DME-3769402)", "pathway_count": 2, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0036064 ciliary basal body;GO:0035869 ciliary transition zone;GO:0120135 distal portion of axoneme;GO:0061822 ciliary cap", "go_biological_process": "GO:0097711 ciliary basal body-plasma membrane docking;GO:0007286 spermatid development;GO:0032880 regulation of protein localization;GO:0060271 cilium assembly;GO:0035735 intraciliary transport involved in cilium assembly", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "B9A0M5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0B4LGJ9-1", "uniprot_id": "A0A0B4LGJ9_DROME", "mass": 60627.0, "length": 537, "protein_name": "2.3.-.-; 2.3.1.15; Glycerol-3-phosphate acyltransferase 4, isoform D", "gene_name": "Gpat4", "organism": "Fruit fly", "refseq_name": "Glycerol-3-phosphate acyltransferase 4, isoform D", "refseq_ac": "NP_001286818", "gene_names_uniprotkb": "Gpat4; 4; CG3209; Dmel\\CG3209; Dmel_CG3209; GPAT4; GPAT; dGPAT4", "gene_names_refseq": "CG3209; DmGPAT3/4; Dmel\\CG3209; GPAT4; GPAT; Gpat4; dGPAT4", "protein_names_uniprotkb": "2.3.-.-; 2.3.1.15; Glycerol-3-phosphate acyltransferase 4, isoform D", "protein_names_refseq": "CG3209-PD; Glycerol-3-phosphate acyltransferase 4, isoform D; Gpat4-PD; glycerol- 3-phosphate acyltransferase 4; glycerol-3-phosphate acyltransferase", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG3209); (R-DME-1483166)", "pathway_count": 2, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.3.-.-;2.3.1.15;2.3.1.23;2.3.1.51", "go_molecular_function": "GO:0004366 glycerol-3-phosphate O-acyltransferase activity", "go_cellular_component": "GO:0016020 membrane;GO:0012505 endomembrane system", "go_biological_process": "GO:0008654 phospholipid biosynthetic process;GO:0034389 lipid droplet organization", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0B4LGJ9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A8JR01-1", "uniprot_id": "A8JR01_DROME", "mass": 343124.0, "length": 3090, "protein_name": "Kramer, isoform I", "gene_name": "kmr", "organism": "Fruit fly", "refseq_name": "kramer, isoform I", "refseq_ac": "NP_001097775", "gene_names_uniprotkb": "kmr; CG14365; CG14366; CG34383; CG9322; Dm_3R:52023; Dmel\\CG34383; Dmel_CG34383; PLEKHA4", "gene_names_refseq": "CG14365; CG14366; CG34383; CG9322; Dm_3R:52023; Dmel\\CG34383; PLEKHA4; kmr", "protein_names_uniprotkb": "Kramer, isoform I", "protein_names_refseq": "CG34383-PI; kmr-PI; kramer, isoform I; kramer", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG34383); (R-DME-1660499)", "pathway_count": 2, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 5, "predicted_n_glycosites": 0, "predicted_o_glycosites": 5, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:1902936 phosphatidylinositol bisphosphate binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0016020 membrane;GO:0031234 extrinsic component of cytoplasmic side of plasma membrane", "go_biological_process": "GO:0090175 regulation of establishment of planar polarity", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A8JR01-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A4D6K4L3-1", "uniprot_id": "A0A4D6K4L3_DROME", "mass": 69073.0, "length": 613, "protein_name": "Palmitoyltransferase", "gene_name": "Patsas", "organism": "Fruit fly", "refseq_name": "patsas, isoform C", "refseq_ac": "NP_001356957", "gene_names_uniprotkb": "Patsas; CG6618; Dmel\\CG6618; Dmel_CG6618", "gene_names_refseq": "CG6618; Dmel\\CG6618; Patsas", "protein_names_uniprotkb": "Palmitoyltransferase; 2.3.1.225", "protein_names_refseq": "CG6618-PC; Patsas-PC; patsas, isoform C", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG6618)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.3.1.225", "go_molecular_function": "GO:0019706 protein-cysteine S-palmitoyltransferase activity", "go_cellular_component": "GO:0016020 membrane;GO:0005794 Golgi apparatus", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A4D6K4L3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0S0WNI0-1", "uniprot_id": "A0A0S0WNI0_DROME", "mass": 68451.0, "length": 596, "protein_name": "DNA double-strand break repair Rad50 ATPase", "gene_name": "CG14538", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform D", "refseq_ac": "NP_001303313", "gene_names_uniprotkb": "CG14538; CG46025; CG7196; Dmel\\CG46025; Dmel_CG46025", "gene_names_refseq": "CG14538; CG46025; CG7196; Dmel\\CG46025", "protein_names_uniprotkb": "DNA double-strand break repair Rad50 ATPase", "protein_names_refseq": "CG46025-PD; uncharacterized protein, isoform D", "tax_id": 7227, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0S0WNI0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A1Z8W8-1", "uniprot_id": "A1Z8W8_DROME", "mass": 220591.0, "length": 1983, "protein_name": "Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1", "gene_name": "garz", "organism": "Fruit fly", "refseq_name": "gartenzwerg, isoform B", "refseq_ac": "NP_610761", "gene_names_uniprotkb": "garz; ARF1GEF; ArfGEF; CG 8487; CG8487; Dmel\\CG8487; Dmel_CG8487; GBF1; GEF; Garz; ang", "gene_names_refseq": "ARF1GEF; ArfGEF; CG 8487; CG8487; Dmel\\CG8487; GBF1; GEF; Garz; ang; garz", "protein_names_uniprotkb": "Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1", "protein_names_refseq": "CG8487-PB; angina; angle wing; gartenzwerg, isoform B; gartenzwerg; garz-PB; sec7-family GEF", "tax_id": 7227, "disease": "Charcot-Marie-Tooth disease dominant intermediate A (Disease Ontology:DOID:0110202)", "pathway": " (dme:Dmel_CG8487); (R-DME-199992); (R-DME-5620916); (R-DME-6807878); (R-DME-6811434)", "pathway_count": 5, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005085 guanyl-nucleotide exchange factor activity;GO:0031267 small GTPase binding", "go_cellular_component": "GO:0005811 lipid droplet;GO:0016020 membrane;GO:0005801 cis-Golgi network;GO:0005793 endoplasmic reticulum-Golgi intermediate compartment;GO:0000137 Golgi cis cisterna", "go_biological_process": "GO:0015031 protein transport;GO:0032940 secretion by cell;GO:0016197 endosomal transport;GO:0007431 salivary gland development;GO:0002064 epithelial cell development", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A1Z8W8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A1Z9Q2-1", "uniprot_id": "A1Z9Q2_DROME", "mass": 22732.0, "length": 200, "protein_name": "Odorant-binding protein 50a, isoform B", "gene_name": "Obp50a", "organism": "Fruit fly", "refseq_name": "Odorant-binding protein 50a, isoform B", "refseq_ac": "NP_995832", "gene_names_uniprotkb": "Obp50a; CG30067; DmelObp50a; Dmel\\CG30067; Dmel_CG30067; anon-AE003814.2", "gene_names_refseq": "CG30067; DmelObp50a; Dmel\\CG30067; Obp50a; anon-AE003814.2", "protein_names_uniprotkb": "Odorant-binding protein 50a, isoform B", "protein_names_refseq": "CG30067-PB; Obp50a-PB; Odorant-binding protein 50a, isoform B", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG30067)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005549 odorant binding", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "GO:0007606 sensory perception of chemical stimulus", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A1Z9Q2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A4UZL3-1", "uniprot_id": "A4UZL3_DROME", "mass": 127910.0, "length": 1141, "protein_name": "Eps15 homology domain containing protein-binding protein 1, isoform F", "gene_name": "Ehbp1", "organism": "Fruit fly", "refseq_name": "Eps15 homology domain containing protein-binding protein 1, isoform F", "refseq_ac": "NP_995865", "gene_names_uniprotkb": "Ehbp1; 2R11; CG15609; Dmel\\CG15609; Dmel_CG15609; EHBP1; dEHBP-1; dEHBP1; ehbp1", "gene_names_refseq": "2R11; CG15609; Dmel\\CG15609; EHBP1; Ehbp1; dEHBP-1; dEHBP1; ehbp1", "protein_names_uniprotkb": "Eps15 homology domain containing protein-binding protein 1, isoform F", "protein_names_refseq": "CG15609-PF; Ehbp1-PF; Eps15 homology domain containing protein-binding protein 1, isoform F", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG15609)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0051015 actin filament binding;GO:0031267 small GTPase binding", "go_cellular_component": "GO:0005768 endosome;GO:0005886 plasma membrane;GO:0005938 cell cortex", "go_biological_process": "GO:0030036 actin cytoskeleton organization;GO:0045747 positive regulation of Notch signaling pathway;GO:0032456 endocytic recycling;GO:0061864 basement membrane constituent secretion;GO:0110010 basolateral protein secretion", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A4UZL3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D1YSG0-1", "uniprot_id": "D1YSG0_DROME", "mass": 1000078.0, "length": 8933, "protein_name": "2.7.11.1; Bent, isoform F", "gene_name": "bt", "organism": "Fruit fly", "refseq_name": "bent, isoform F", "refseq_ac": "NP_001162825", "gene_names_uniprotkb": "bt; 39c-18; Bt; CG10285; CG1479; CG32019; CT3598; CT8086; Dmel\\CG32019; Dmel_CG32019; Prj; l(2)23; l(2)2; l(4)102CDa; l(4)21; l(4)23; l(4)2; l(4)37; l(4)38; l(4)PT-2; projectin; titin", "gene_names_refseq": "39c-18; Bt; CG10285; CG1479; CG32019; CT3598; CT8086; Dmel\\CG32019; Prj; bt; l(2)23; l(2)2; l(4)102CDa; l(4)21; l(4)23; l(4)2; l(4)37; l(4)38; l(4)PT-2; projectin; titin", "protein_names_uniprotkb": "2.7.11.1; Bent, isoform F", "protein_names_refseq": "C-protein; CG32019-PF; bent, isoform F; bent; bt-PF; lethal(4) Powell, Tennessee-2; myosin LCK; projectin myosin light chain kinase; twitchin", "tax_id": 7227, "disease": "atrial fibrillation (Disease Ontology:DOID:0060224); congenital myopathy 5 (Disease Ontology:DOID:0081341); autosomal recessive limb-girdle muscular dystrophy type 2J (Disease Ontology:DOID:0110283); hypertrophic cardiomyopathy 9 (Disease Ontology:DOID:0110315); dilated cardiomyopathy 1G (Disease Ontology:DOID:0110430); tibial muscular dystrophy (Disease Ontology:DOID:0111078); myofibrillar myopathy 9 (Disease Ontology:DOID:0111188); dilated cardiomyopathy (Disease Ontology:DOID:12930); coronary artery disease (Disease Ontology:DOID:3393); myocardial infarction (Disease Ontology:DOID:5844)", "pathway": " (dme:Dmel_CG32019)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 10, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0008307 structural constituent of muscle;GO:0004672 protein kinase activity", "go_cellular_component": "GO:0030017 sarcomere;GO:0031674 I band;GO:0030018 Z disc;GO:0031672 A band;GO:0031430 M band", "go_biological_process": "GO:0050793 regulation of developmental process;GO:0045214 sarcomere organization;GO:0007498 mesoderm development;GO:0071689 muscle thin filament assembly;GO:0051239 regulation of multicellular organismal process", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "D1YSG0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A8DYY1-1", "uniprot_id": "A8DYY1_DROME", "mass": 64270.0, "length": 554, "protein_name": "E3 ubiquitin-protein ligase APD1-4 middle domain-containing protein", "gene_name": "CG9524; Dmel\\CG31886; anon-WO0172774.161", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform B", "refseq_ac": "NP_001097129", "gene_names_uniprotkb": "CG9524; Dmel\\CG31886; anon-WO0172774.161; CG31886; CG9524; Dmel\\CG31886; Dmel_CG31886; anon-WO0172774.159; anon-WO0172774.161", "gene_names_refseq": "CG31886; CG9524; Dmel\\CG31886; anon-WO0172774.159; anon-WO0172774.161", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase APD1-4 middle domain-containing protein", "protein_names_refseq": "CG31886-PB; uncharacterized protein, isoform B", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG31886)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A8DYY1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A8JNS4-1", "uniprot_id": "A8JNS4_DROME", "mass": 68856.0, "length": 635, "protein_name": "Starvin, isoform E", "gene_name": "stv", "organism": "Fruit fly", "refseq_name": "starvin, isoform E", "refseq_ac": "NP_001097600", "gene_names_uniprotkb": "stv; CG10745; CG14108; CG32130; Dmel\\CG32130; Dmel_CG32130; GH04349; Stv; cg32130; dBAG3; l(3)00543", "gene_names_refseq": "CG10745; CG14108; CG32130; Dmel\\CG32130; GH04349; Stv; cg32130; dBAG3; l(3)00543; stv", "protein_names_uniprotkb": "Starvin, isoform E", "protein_names_refseq": "CG32130-PE; Dm-Starvin; lethal (3) 00543; starvin, isoform E; starving; starvin; stv-PE", "tax_id": 7227, "disease": "cardiomyopathy (Disease Ontology:DOID:0050700); autosomal dominant distal hereditary motor neuronopathy 15 (Disease Ontology:DOID:0051042); Charcot-Marie-Tooth disease axonal type 2JJ (Disease Ontology:DOID:0051043); myofibrillar myopathy 6 (Disease Ontology:DOID:0080097); dilated cardiomyopathy 1HH (Disease Ontology:DOID:0110448); dilated cardiomyopathy (Disease Ontology:DOID:12930); pancreatic cancer (Disease Ontology:DOID:1793); glioblastoma (Disease Ontology:DOID:3068)", "pathway": " (dme:Dmel_CG32130); (R-DME-3371453)", "pathway_count": 2, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 8, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0051087 protein-folding chaperone binding;GO:0031072 heat shock protein binding;GO:0000774 adenyl-nucleotide exchange factor activity", "go_cellular_component": "GO:0005829 cytosol;GO:0030018 Z disc;GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0016020 membrane", "go_biological_process": "GO:0050821 protein stabilization", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A8JNS4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "M9MSL4-1", "uniprot_id": "M9MSL4_DROME", "mass": 123763.0, "length": 1065, "protein_name": "Centrosomal protein 135kDa, isoform B", "gene_name": "Cep135", "organism": "Fruit fly", "refseq_name": "centrosomal protein 135kDa, isoform B", "refseq_ac": "NP_001189108", "gene_names_uniprotkb": "Cep135; BLD10; Bld-10; Bld10p; Bld10; CEP135; CG17081; DBld10; DCep135; DmBLD10; Dmel\\CG17081; Dmel_CG17081; bld10; dbld10", "gene_names_refseq": "BLD10; Bld-10; Bld10p; Bld10; CEP135; CG17081; Cep135/bld10; Cep135; DBld10; DCep135/Bld10; DCep135; DmBLD10; Dmel\\CG17081; bld10; dbld10", "protein_names_uniprotkb": "Centrosomal protein 135kDa, isoform B", "protein_names_refseq": "CG17081-PB; Cep135-PB; centrosomal protein 135kDa, isoform B", "tax_id": 7227, "disease": "primary autosomal recessive microcephaly 8 (Disease Ontology:DOID:0070282); spermatogenic failure 26 (Disease Ontology:DOID:0111924)", "pathway": " (dme:Dmel_CG17081)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008017 microtubule binding", "go_cellular_component": "GO:0005813 centrosome;GO:0005814 centriole;GO:0036064 ciliary basal body;GO:0035869 ciliary transition zone", "go_biological_process": "GO:0007026 negative regulation of microtubule depolymerization;GO:0007098 centrosome cycle;GO:0055059 asymmetric neuroblast division;GO:0007100 mitotic centrosome separation;GO:0007288 sperm axoneme assembly", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "M9MSL4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "B7YZW3-1", "uniprot_id": "B7YZW3_DROME", "mass": 223201.0, "length": 2064, "protein_name": "Miles to go, isoform E", "gene_name": "mtgo", "organism": "Fruit fly", "refseq_name": "miles to go, isoform E", "refseq_ac": "NP_001137829", "gene_names_uniprotkb": "mtgo; CG13260; CG13261; CG31738; CG42389; CG4668; CT15043; CT15049; Dmel\\CG42389; Dmel_CG42389; anon-EST:Liang-1.16; clone 1.16", "gene_names_refseq": "CG13260; CG13261; CG31738; CG42389; CG4668; CT15043; CT15049; Dmel\\CG42389; anon-EST:Liang-1.16; clone 1.16; mtgo", "protein_names_uniprotkb": "Miles to go, isoform E", "protein_names_refseq": "CG42389-PE; miles to go, isoform E; mtgo-PE", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG42389)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "B7YZW3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "M9MRW9-1", "uniprot_id": "M9MRW9_DROME", "mass": 19081.0, "length": 161, "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG42654", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform C", "refseq_ac": "NP_001189134", "gene_names_uniprotkb": "Dmel\\CG42654; CG42654; Dmel_CG42654", "gene_names_refseq": "CG42654; Dmel\\CG42654", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "CG42654-PC; uncharacterized protein, isoform C", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG42654)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "M9MRW9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0S0WP14-1", "uniprot_id": "A0A0S0WP14_DROME", "mass": 88050.0, "length": 811, "protein_name": "Capricious, isoform E", "gene_name": "caps", "organism": "Fruit fly", "refseq_name": "capricious, isoform E", "refseq_ac": "NP_001303391", "gene_names_uniprotkb": "caps; 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:GABA-B-R2; BcDNA:GH07312; CG6706; D-GABA-B-R2; D-GABA[[B]]R2; D-Gaba2; Dmel\\CG6706; Dmel_CG6706; GABA B R2; GABA-BR2; GABA-[[B]]R2; GABA2; GABAB(R2); GABAB-R2; GABABR-R2; GABABR2; GABA[[B]]-R2; GABA[[B]]R2; GB2; GBR; GH07312; anon-WO0170980.58; anon-WO0170980.59; dGB2", "gene_names_refseq": ":GABA-B-R2; BcDNA:GH07312; CG6706; D-GABA-B-R2; D-GABA[[B]]R2; D-Gaba2; Dmel\\CG6706; GABA B R2; GABA-B-R2; GABA-BR2; GABA-[[B]]R2; GABA2; GABAB(R2); GABAB-R2; GABABR-R2; GABABR2; GABA[[B]]-R2; GABA[[B]]R2; GB2; GBR; GH07312; anon-WO0170980.58; anon-WO0170980.59; dGB2", "protein_names_uniprotkb": "Gamma-aminobutyric acid type B receptor subunit 2; G-protein coupled receptor 51", "protein_names_refseq": "CG6706-PC; GABA-B-R2-PC; GABA[[B]]- 2 receptor; GABA[[B]]receptor2; metabotropic GABA-B receptor subtype 2, isoform C; metabotropic GABA-B receptor subtype 2; metabotropic GABA[[B]] receptor 2", "tax_id": 7227, "disease": "nicotine dependence (Disease Ontology:DOID:0050742); developmental and epileptic encephalopathy 59 (Disease Ontology:DOID:0080291); alcohol use disorder (Disease Ontology:DOID:1574)", "pathway": " (dme:Dmel_CG6706); (R-DME-1296041); (R-DME-418594); (R-DME-420499); (R-DME-977444); (R-DME-997272)", "pathway_count": 6, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 3, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0046982 protein heterodimerization activity;GO:0004965 G protein-coupled GABA receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane;GO:0045211 postsynaptic membrane;GO:0038039 G protein-coupled receptor heterodimeric complex", "go_biological_process": "GO:0042048 olfactory behavior;GO:0007186 G protein-coupled receptor signaling pathway;GO:0007193 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway;GO:0007214 gamma-aminobutyric acid signaling pathway;GO:0046676 negative regulation of insulin secretion", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0B4LHR4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0B4LIB4-1", "uniprot_id": "A0A0B4LIB4_DROME", "mass": 7729.0, "length": 65, "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG44259", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": "NP_001287373", "gene_names_uniprotkb": "Dmel\\CG44259; CG44259; Dmel_CG44259; FBgn0265199", "gene_names_refseq": "CG44259; Dmel\\CG44259; FBgn0265199", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "CG44259-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG44259)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0B4LIB4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0B7P7M6-1", "uniprot_id": "A0A0B7P7M6_DROME", "mass": 104907.0, "length": 890, "protein_name": "Lethal (2) 41Ab, isoform A", "gene_name": "l(2)41Ab", "organism": "Fruit fly", "refseq_name": "lethal (2) 41Ab, isoform A", "refseq_ac": "NP_001104357", "gene_names_uniprotkb": "l(2)41Ab; 1(2R)B; 41Ab; CG40214; CG40334; CG41265; Dmel\\CG41265; Dmel_CG41265; GroupI; l(2)EMS45-10; l(2R)B", "gene_names_refseq": "1(2R)B; 41Ab; CG40214; CG40334; CG41265; Dmel\\CG41265; GroupI; l(2)41Ab; l(2)EMS45-10; l(2R)B", "protein_names_uniprotkb": "Lethal (2) 41Ab, isoform A", "protein_names_refseq": "CG41265-PA; l(2)41Ab-PA; lethal (2) 41Ab, isoform A", "tax_id": 7227, "disease": "primary ciliary dyskinesia 15 (Disease Ontology:DOID:0110623); primary ciliary dyskinesia (Disease Ontology:DOID:9562)", "pathway": " (dme:Dmel_CG41265)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 2, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005930 axoneme;GO:0097731 9+0 non-motile cilium", "go_biological_process": "GO:0003341 cilium movement;GO:0036159 inner dynein arm assembly;GO:0070286 axonemal dynein complex assembly;GO:0035082 axoneme assembly", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A0B7P7M6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A0C4DH96-1", "uniprot_id": "A0A0C4DH96_DROME", "mass": 126147.0, "length": 1174, "protein_name": "Sidestep V, isoform B", "gene_name": "side-V", "organism": "Fruit fly", "refseq_name": "sidestep V, isoform B", "refseq_ac": "NP_611765", "gene_names_uniprotkb": "side-V; 34371; CG13546; CG13547; CG13548; CG30188; CG34371; CT32921; CT32922; Dmel\\CG34371; Dmel_CG34371", "gene_names_refseq": "34371; CG13546; CG13547; CG13548; CG30188; CG34371; CT32921; CT32922; Dmel\\CG34371; side-V", "protein_names_uniprotkb": "Sidestep V, isoform B", "protein_names_refseq": "CG34371-PB; side-V-PB; sidestep V, isoform B", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG34371)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357;40245499", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "A0A0C4DH96-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A8JQT5-1", "uniprot_id": "A8JQT5_DROME", "mass": 473474.0, "length": 4273, "protein_name": "Moesin/ezrin/radixin homolog 1", "gene_name": "Cdep", "organism": "Fruit fly", "refseq_name": "Chondrocyte-derived ezrin-like domain containing protein, isoform G", "refseq_ac": "NP_001097685", "gene_names_uniprotkb": "Cdep; 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glomerulonephritis (Disease Ontology:DOID:2921); familial Mediterranean fever (Disease Ontology:DOID:2987); brain infarction (Disease Ontology:DOID:3454); liver cirrhosis (Disease Ontology:DOID:5082); oral submucous fibrosis (Disease Ontology:DOID:5773); end stage renal disease (Disease Ontology:DOID:783); chronic myeloid leukemia (Disease Ontology:DOID:8552); pulmonary embolism (Disease Ontology:DOID:9477); acute lymphoblastic leukemia (Disease Ontology:DOID:9952)", "pathway": " (dme:Dmel_CG17875)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 22, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005506 iron ion binding;GO:0016491 oxidoreductase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A2U8U1P3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A384ZD34-1", "uniprot_id": "A0A384ZD34_DROME", "mass": 38787.0, "length": 341, "protein_name": "Mitochondrial translation initiation factor 3, isoform C", "gene_name": "mIF3", "organism": "Fruit fly", "refseq_name": "mitochondrial translation initiation factor 3, isoform C", "refseq_ac": "NP_001350856", "gene_names_uniprotkb": "mIF3; 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CG46383; Dmel_CG46383", "gene_names_refseq": "", "protein_names_uniprotkb": "RING-type domain-containing protein", "protein_names_refseq": "", "tax_id": 7227, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0060255 regulation of macromolecule metabolic process", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A0A4D6K4B0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A4D6K823-1", "uniprot_id": "A0A4D6K823_DROME", "mass": 49161.0, "length": 439, "protein_name": "Mitogen-activated protein kinase", "gene_name": "nmo", "organism": "Fruit fly", "refseq_name": "nemo, isoform I", "refseq_ac": "NP_001356976", "gene_names_uniprotkb": "nmo; CG7892; Dmel\\CG7892; Dmel_CG7892; NEMO; NLK; Nemo; Nlk; Nmo; ORE-6; adk1; adk; anon-EST:Gibbs3; anon-EST:Liang-2.43; anon-WO0118547.332; anon-WO0140519.256; anon-WO0172774.138; clone 2.43", "gene_names_refseq": "CG7892; Dmel\\CG7892; NEMO/NLK; NEMO; NLK; Nemo; Nlk; Nmo; ORE-6; adk1; adk; anon-EST:Gibbs3; anon-EST:Liang-2.43; anon-WO0118547.332; anon-WO0140519.256; anon-WO0172774.138; clone 2.43; nmo", "protein_names_uniprotkb": "Mitogen-activated protein kinase; 2.7.11.24", "protein_names_refseq": "CG7892-PI; NEMO; Nemo-like kinase; adirondack; dNEMO; nemo, isoform I; nmo-PI", "tax_id": 7227, "disease": "myocardial infarction (Disease Ontology:DOID:5844)", "pathway": " (dme:Dmel_CG7892); (R-DME-4086398)", "pathway_count": 2, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "Has a role in the Wnt signaling pathway controlling the asymmetry of cell divisions during embryogenesis. Operates in the AB and EMS cell lineages influencing cell specification. Required for body wall muscle development, endoderm development, pop-1 asymmetry and T-cell division asymmetry. Component of the beta-catenin-lit-1 complex which promotes the phosphorylation, down-regulation and subcellular relocation of pop-1. Regulates plp-1 nuclear localization in embryos. 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CG33919; Dmel_CG33919", "gene_names_refseq": "CG33919; Dmel\\CG33919", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "CG33919-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG33919)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A1Z6L8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A1Z6Q3-1", "uniprot_id": "A1Z6Q3_DROME", "mass": 76926.0, "length": 656, "protein_name": "Acyltransferase 3 domain-containing protein", "gene_name": "Dmel\\CG9447", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": "NP_610243", "gene_names_uniprotkb": "Dmel\\CG9447; 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146747_at; CG2137; Dmel\\CG2137; Dmel_CG2137; GPO-2; GPO; Gpo; alpha-GPO; gpo-2", "gene_names_refseq": "146747_at; CG2137; Dmel\\CG2137; GPO-2; GPO; Gpo2; Gpo; alpha-GPO; gpo-2", "protein_names_uniprotkb": "Glycerol-3-phosphate dehydrogenase; 1.1.5.3", "protein_names_refseq": "CG2137-PA; Gpo2-PA; alpha glycerophosphate oxidase 2; glycerophosphate oxidase 2", "tax_id": 7227, "disease": "type 2 diabetes mellitus (Disease Ontology:DOID:9352)", "pathway": " (dme:Dmel_CG2137)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.1.5.3", "go_molecular_function": "GO:0004368 glycerol-3-phosphate dehydrogenase (quinone) activity;GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0006127 glycerol-3-phosphate shuttle;GO:0006072 glycerol-3-phosphate metabolic process", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A1Z707-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A1Z765-1", "uniprot_id": "A1Z765_DROME", "mass": 21652.0, "length": 202, "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG12159", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform A", "refseq_ac": "NP_610330", "gene_names_uniprotkb": "Dmel\\CG12159; 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CG13188; Dmel\\CG13188; Dmel_CG13188; Exp", "gene_names_refseq": "CG13188; Dmel\\CG13188; Exp; exp", "protein_names_uniprotkb": "Expansion, isoform A", "protein_names_refseq": "CG13188-PA; exp-PA; expansion, isoform A; expansion", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG13188)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0045177 apical part of cell;GO:0098592 cytoplasmic side of apical plasma membrane", "go_biological_process": "GO:0050793 regulation of developmental process;GO:0060439 trachea morphogenesis;GO:0006355 regulation of DNA-templated transcription;GO:0009791 post-embryonic development;GO:0051239 regulation of multicellular organismal process", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A1Z8R1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A1Z8U0-1", "uniprot_id": "A1Z8U0_DROME", "mass": 279578.0, "length": 2396, "protein_name": "Pre-mRNA-processing-splicing factor 8", "gene_name": "Prp8", "organism": "Fruit fly", "refseq_name": "pre-mRNA processing factor 8", "refseq_ac": "NP_610735", "gene_names_uniprotkb": "Prp8; 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Functions as a scaffold that mediates the ordered assembly of spliceosomal proteins and snRNAs. Required for the assembly of the U4/U6-U5 tri-snRNP complex, a building block of the spliceosome. Functions as a scaffold that positions spliceosomal U2, U5 and U6 snRNAs at splice sites on pre-mRNA substrates, so that splicing can occur. Interacts with both the 5' and the 3' splice site., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0097157 pre-mRNA intronic binding;GO:0030620 U2 snRNA binding;GO:0017069 snRNA binding;GO:0030619 U1 snRNA binding;GO:0017070 U6 snRNA binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0071013 catalytic step 2 spliceosome;GO:0071011 precatalytic spliceosome;GO:0030532 small nuclear ribonucleoprotein complex;GO:0005682 U5 snRNP", "go_biological_process": "GO:0000244 spliceosomal tri-snRNP complex assembly;GO:0000398 mRNA splicing, via spliceosome;GO:0007419 ventral cord development", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A1Z8U0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A1Z8Y8-1", "uniprot_id": "A1Z8Y8_DROME", "mass": 18966.0, "length": 166, "protein_name": "Cuticular protein 49Ad", "gene_name": "Cpr49Ad", "organism": "Fruit fly", "refseq_name": "cuticular protein 49Ad", "refseq_ac": "NP_610773", "gene_names_uniprotkb": "Cpr49Ad; 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CG13157; Dmel_CG13157", "gene_names_refseq": "CG13157; Dmel\\CG13157", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "CG13157-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG13157)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A1Z8Z8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A1Z910-1", "uniprot_id": "A1Z910_DROME", "mass": 73797.0, "length": 633, "protein_name": "Neprilysin-like 10", "gene_name": "Nepl10", "organism": "Fruit fly", "refseq_name": "Neprilysin-like 10", "refseq_ac": "NP_610787", "gene_names_uniprotkb": "Nepl10; CG8550; Dmel\\CG8550; Dmel_CG8550", "gene_names_refseq": "CG8550; Dmel\\CG8550; Nepl10", "protein_names_uniprotkb": "Neprilysin-like 10", "protein_names_refseq": "CG8550-PA; Nepl10-PA; Neprilysin-like 10", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG8550)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0006508 proteolysis", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A1Z910-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A1Z931-1", "uniprot_id": "A1Z931_DROME", "mass": 26208.0, "length": 225, "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG33792", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": "NP_001027411", "gene_names_uniprotkb": "Dmel\\CG33792; 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CG18324; Dmel_CG18324", "gene_names_refseq": "CG18324; Dmel\\CG18324", "protein_names_uniprotkb": "Solute carrier family 25 member 35", "protein_names_refseq": "CG18324-PB; uncharacterized protein, isoform B", "tax_id": 7227, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0022857 transmembrane transporter activity", "go_cellular_component": "GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:1990542 mitochondrial transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A1Z9M0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A1Z9M6-1", "uniprot_id": "A1Z9M6_DROME", "mass": 60838.0, "length": 549, "protein_name": "Vesicular inhibitory amino acid transporter", "gene_name": "VGAT", "organism": "Fruit fly", "refseq_name": "vesicular GABA transporter", "refseq_ac": "NP_610938", "gene_names_uniprotkb": "VGAT; CG8394.2; CG8394; Dmel\\CG8394; Dmel_CG8394; VIAAT; Vgat; dVGAT; vGAT", "gene_names_refseq": "CG8394.2; CG8394; Dmel\\CG8394; VGAT; VIAAT; Vgat; dVGAT; vGAT", "protein_names_uniprotkb": "Vesicular inhibitory amino acid transporter; Solute carrier family 32 member 1; Vesicular GABA transporter", "protein_names_refseq": "CG8394-PA; VGAT-PA; vesicular GABA transporter", "tax_id": 7227, "disease": "generalized epilepsy with febrile seizures plus (Disease Ontology:DOID:0060170); developmental and epileptic encephalopathy (Disease Ontology:DOID:0112202); alcohol use disorder (Disease Ontology:DOID:1574); temporal lobe epilepsy (Disease Ontology:DOID:3328)", "pathway": " (dme:Dmel_CG8394); (R-DME-442660); (R-DME-888590)", "pathway_count": 3, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "Antiporter that exchanges vesicular protons for cytosolic 4-aminobutanoate or to a lesser extend glycine, thus allowing their secretion from nerve terminals. The transport is equally dependent on the chemical and electrical components of the proton gradient. May also transport beta-alanine. Acidification of GABAergic synaptic vesicles is a prerequisite for 4-aminobutanoate uptake., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 4, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0015187 glycine transmembrane transporter activity;GO:0015185 gamma-aminobutyric acid transmembrane transporter activity;GO:0140800 gamma-aminobutyric acid:proton antiporter activity", "go_cellular_component": "GO:0030672 synaptic vesicle membrane;GO:0060077 inhibitory synapse;GO:0044292 dendrite terminus;GO:0044306 neuron projection terminus", "go_biological_process": "GO:0015816 glycine transport;GO:0030431 sleep;GO:0007632 visual behavior;GO:0015812 gamma-aminobutyric acid transport;GO:0051939 gamma-aminobutyric acid import", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A1Z9M6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A1Z9Q6-1", "uniprot_id": "A1Z9Q6_DROME", "mass": 22225.0, "length": 196, "protein_name": "Odorant-binding protein 50e", "gene_name": "Obp50e", "organism": "Fruit fly", "refseq_name": "Odorant-binding protein 50e", "refseq_ac": "NP_610959", "gene_names_uniprotkb": "Obp50e; CG13939; DmelObp50e; Dmel\\CG13939; Dmel_CG13939", "gene_names_refseq": "CG13939; DmelObp50e; Dmel\\CG13939; Obp50e", "protein_names_uniprotkb": "Odorant-binding protein 50e", "protein_names_refseq": "CG13939-PA; Obp50e-PA; Odorant-binding protein 50e", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG13939)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005549 odorant binding", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "GO:0007606 sensory perception of chemical stimulus", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A1Z9Q6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A1Z9Q8-1", "uniprot_id": "A1Z9Q8_DROME", "mass": 56343.0, "length": 504, "protein_name": "Diuretic hormone receptor", "gene_name": "Dh44-R1", "organism": "Fruit fly", "refseq_name": "diuretic hormone 44 receptor 1", "refseq_ac": "NP_610960", "gene_names_uniprotkb": "Dh44-R1; CG8422; DH-R; DH44-R1; DH44R1; DH[[44]]-R1; Dh44R1; DmeCG8422; Dmel\\CG8422; Dmel_CG8422; anon-WO0170980.100; anon-WO0170980.101", "gene_names_refseq": "CG8422; DH-R; DH44-R1; DH44R1; DH[[44]]-R1; Dh44-R1; Dh44R1; DmeCG8422; Dmel\\CG8422; anon-WO0170980.100; anon-WO0170980.101", "protein_names_uniprotkb": "Diuretic hormone receptor", "protein_names_refseq": "CG8422-PA; CRF-like diuretic hormone receptor 1; DH44 receptor; DH44-receptor; DH[[44]] receptor; Dh44 receptor 1; Dh44-R1-PA; diuretic hormone 44 receptor 1", "tax_id": 7227, "disease": "fetal alcohol spectrum disorder (Disease Ontology:DOID:0050696); colitis (Disease Ontology:DOID:0060180); hypertension (Disease Ontology:DOID:10763); thromboangiitis obliterans (Disease Ontology:DOID:12918); alcohol use disorder (Disease Ontology:DOID:1574); depressive disorder (Disease Ontology:DOID:1596); asthma (Disease Ontology:DOID:2841); chronic obstructive pulmonary disease (Disease Ontology:DOID:3083); ischemia (Disease Ontology:DOID:326); functional colonic disease (Disease Ontology:DOID:3877); rhinitis (Disease Ontology:DOID:4483); muscular atrophy (Disease Ontology:DOID:767); type 2 diabetes mellitus (Disease Ontology:DOID:9352); irritable bowel syndrome (Disease Ontology:DOID:9778); obesity (Disease Ontology:DOID:9970); heroin dependence (Disease Ontology:DOID:9976)", "pathway": " (dme:Dmel_CG8422)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "Receptor for the insect diurectic hormone. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 16, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0017046 peptide hormone binding;GO:0008528 G protein-coupled peptide receptor activity;GO:0004948 calcitonin receptor activity;GO:0008188 neuropeptide receptor activity;GO:0008036 diuretic hormone receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane", "go_biological_process": "GO:0007166 cell surface receptor signaling pathway;GO:0007186 G protein-coupled receptor signaling pathway;GO:0007188 adenylate cyclase-modulating G protein-coupled receptor signaling pathway;GO:0009755 hormone-mediated signaling pathway", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A1Z9Q8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A1Z9S6-1", "uniprot_id": "A1Z9S6_DROME", "mass": 355974.0, "length": 3257, "protein_name": "Su(Var)2-HP2, isoform A", "gene_name": "Su(var)2-HP2", "organism": "Fruit fly", "refseq_name": "Su(var)2-HP2, isoform A", "refseq_ac": "NP_610972", "gene_names_uniprotkb": "Su(var)2-HP2; CG12864; Dmel\\CG12864; Dmel_CG12864; HP2; Hp2; SU(VAR)2-HP2", "gene_names_refseq": "CG12864; Dmel\\CG12864; HP2; Hp2; SU(VAR)2-HP2; Su(var)2-HP2", "protein_names_uniprotkb": "Su(Var)2-HP2, isoform A", "protein_names_refseq": "CG12864-PA; Su(var)2-HP2, isoform A; Su(var)2-HP2-PA; heterochromatic protein 2; heterochromatin protein 2", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG12864)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding", "go_cellular_component": "GO:0000793 condensed chromosome;GO:0000792 heterochromatin;GO:0005700 polytene chromosome", "go_biological_process": "GO:0007076 mitotic chromosome condensation;GO:0031507 heterochromatin formation;GO:0051276 chromosome organization", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A1Z9S6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A1Z9S8-1", "uniprot_id": "A1Z9S8_DROME", "mass": 51083.0, "length": 437, "protein_name": "Zinc finger CCHC domain-containing protein 4", "gene_name": "Dmel\\CG12863", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": "NP_610973", "gene_names_uniprotkb": "Dmel\\CG12863; CG12863; Dmel_CG12863", "gene_names_refseq": "CG12863; Dmel\\CG12863", "protein_names_uniprotkb": "Zinc finger CCHC domain-containing protein 4", "protein_names_refseq": "CG12863-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG12863)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0003676 nucleic acid binding;GO:0008988 rRNA (adenine-N6-)-methyltransferase activity", "go_cellular_component": "GO:0005730 nucleolus;GO:0005737 cytoplasm", "go_biological_process": "GO:0031167 rRNA methylation", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A1Z9S8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A1Z9V4-1", "uniprot_id": "A1Z9V4_DROME", "mass": 25025.0, "length": 224, "protein_name": "Uncharacterized protein", "gene_name": "CT28709", "organism": "Fruit fly", "refseq_name": "uncharacterized protein, isoform A", "refseq_ac": "NP_725422", "gene_names_uniprotkb": "CT28709; CG10205; Dmel\\CG10205; Dmel_CG10205", "gene_names_refseq": "CG10205; CT28709; Dmel\\CG10205", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "CG10205-PA; uncharacterized protein, isoform A", "tax_id": 7227, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A1Z9V4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A1ZA17-1", "uniprot_id": "A1ZA17_DROME", "mass": 69505.0, "length": 594, "protein_name": "Ionotropic receptor 52d", "gene_name": "Ir52d", "organism": "Fruit fly", "refseq_name": "ionotropic receptor 52d", "refseq_ac": "NP_611042", "gene_names_uniprotkb": "Ir52d; 52d; CG12961; CG30464; DmelIR52d; Dmel\\CG30464; Dmel_CG30464; IR52d", "gene_names_refseq": "52d; CG12961; CG30464; DmelIR52d; Dmel\\CG30464; IR52d; Ir52d", "protein_names_uniprotkb": "Ionotropic receptor 52d", "protein_names_refseq": "CG30464-PB; Ir52d-PB; ionotropic receptor 52d", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG30464)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0015276 ligand-gated monoatomic ion channel activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane", "go_biological_process": "GO:0009593 detection of chemical stimulus;GO:0019098 reproductive behavior", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A1ZA17-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A1ZA22-1", "uniprot_id": "A1ZA22_DROME", "mass": 50671.0, "length": 455, "protein_name": "Translation initiation factor eIF2B subunit gamma", "gene_name": "eIF2Bgamma", "organism": "Fruit fly", "refseq_name": "eukaryotic translation initiation factor 2B subunit gamma", "refseq_ac": "NP_611046", "gene_names_uniprotkb": "eIF2Bgamma; 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CG17288; CG30457-PA; CG30457; Dmel_CG30457", "gene_names_refseq": "CG17288; CG30457-PA; CG30457; Dmel\\CG30457", "protein_names_uniprotkb": "Skin secretory protein xP2-like", "protein_names_refseq": "CG30457-PA; uncharacterized protein", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG30457)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A1ZAR4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A1ZAS8-1", "uniprot_id": "A1ZAS8_DROME", "mass": 83892.0, "length": 754, "protein_name": "3.1.3.-; 3.1.3.64; Egg-derived tyrosine phosphatase, isoform C", "gene_name": "EDTP", "organism": "Fruit fly", "refseq_name": "Egg-derived tyrosine phosphatase, isoform C", "refseq_ac": "NP_995873", "gene_names_uniprotkb": "EDTP; BcDNA:LD23181; CG6542; D-EDTP; Dmel\\CG6542; Dmel_CG6542; anon-WO0118547.124", "gene_names_refseq": "BcDNA:LD23181; CG6542; D-EDTP; Dmel\\CG6542; EDTP; anon-WO0118547.124", "protein_names_uniprotkb": "3.1.3.-; 3.1.3.64; Egg-derived tyrosine phosphatase, isoform C", "protein_names_refseq": "CG6542-PC; EDTP-PC; Egg-derived tyrosine phosphatase, isoform C", "tax_id": 7227, "disease": "centronuclear myopathy 1 (Disease Ontology:DOID:0111223)", "pathway": " (R-DME-1632852); (R-DME-1660499)", "pathway_count": 2, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 1, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.1.3.-;3.1.3.64;3.1.3.95", "go_molecular_function": "GO:0008138 protein tyrosine/serine/threonine phosphatase activity;GO:0004438 phosphatidylinositol-3-phosphate phosphatase activity", "go_cellular_component": "", "go_biological_process": "GO:0048477 oogenesis", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A1ZAS8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A1ZAW6-1", "uniprot_id": "A1ZAW6_DROME", "mass": 17426.0, "length": 155, "protein_name": "Uncharacterized protein", "gene_name": "BcDNA:RE11282", "organism": "Fruit fly", "refseq_name": "uncharacterized protein", "refseq_ac": "NP_725699", "gene_names_uniprotkb": "BcDNA:RE11282; 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56b; CG15129; CG30129; DmelObp56b; Dmel\\CG30129; Dmel_CG30129; OBP56b", "gene_names_refseq": "56b; CG15129; CG30129; DmelObp56b; Dmel\\CG30129; OBP56b; Obp56b", "protein_names_uniprotkb": "Odorant-binding protein 56b", "protein_names_refseq": "CG30129-PA; Obp56b-PA; Odorant-binding protein 56b", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG30129)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005549 odorant binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0005615 extracellular space", "go_biological_process": "GO:0007608 sensory perception of smell;GO:0007606 sensory perception of chemical stimulus", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A1ZBP7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A1ZBP9-1", "uniprot_id": "A1ZBP9_DROME", "mass": 28055.0, "length": 245, "protein_name": "Odorant-binding protein 56c, isoform B", "gene_name": "Obp56c", "organism": "Fruit fly", "refseq_name": "Odorant-binding protein 56c, isoform B", "refseq_ac": "NP_995902", "gene_names_uniprotkb": "Obp56c; 56c; CG15129; CG30128; DmelObp56c; Dmel\\CG30128; Dmel_CG30128; OBP56c", "gene_names_refseq": "56c; CG15129; CG30128; DmelObp56c; Dmel\\CG30128; OBP56c; Obp56c", "protein_names_uniprotkb": "Odorant-binding protein 56c, isoform B", "protein_names_refseq": "CG30128-PB; Obp56c-PB; Odorant-binding protein 56c, isoform B", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG30128)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005549 odorant binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0005615 extracellular space", "go_biological_process": "GO:0007606 sensory perception of chemical stimulus;GO:0007608 sensory perception of smell", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A1ZBP9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A1ZBR2-1", "uniprot_id": "A1ZBR2_DROME", "mass": 154819.0, "length": 1385, "protein_name": "18 wheeler", "gene_name": "18w", "organism": "Fruit fly", "refseq_name": "18 wheeler", "refseq_ac": "NP_476814", "gene_names_uniprotkb": "18w; 18-wheeler; 18-w; 18W; CG8896; CT25100; Dmel\\CG8896; Dmel_CG8896; EP-709; Toll-2; Toll2; l(2)00053; tlr; toll-2; toll", "gene_names_refseq": "18-wheeler; 18-w; 18W; 18w; CG8896; CT25100; Dmel\\CG8896; EP-709; Toll-2; Toll2; l(2)00053; tlr; toll-2; toll", "protein_names_uniprotkb": "18 wheeler", "protein_names_refseq": "18 wheeler; 18-wheeler; 18Wheeler; 18w-PA; CG8896-PA; Toll-2; toll like receptor; toll receptor; wheeler", "tax_id": 7227, "disease": "", "pathway": " (dme:Dmel_CG8896)", "pathway_count": 1, "publication_count": 11, "publication_id_list": "10731132;12537568;12537572;12537573;12537574;16110336;17569856;17569867;25589440;26109356;26109357", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004888 transmembrane signaling receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0006955 immune response;GO:0007155 cell adhesion;GO:0007165 signal transduction;GO:0019731 antibacterial humoral response;GO:0045087 innate immune response", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "A1ZBR2-1", "record_type": "protein" } ]