[ { "uniprot_canonical_ac": "A0A3Q1MIH5-1", "uniprot_id": "A0A3Q1MIH5_BOVIN", "mass": 186833.0, "length": 1708, "protein_name": "Synaptojanin-1", "gene_name": "SYNJ1", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "SYNJ1", "gene_names_refseq": "", "protein_names_uniprotkb": "Synaptojanin-1; 3.1.3.36; Synaptic inositol 1,4,5-trisphosphate 5-phosphatase 1", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Phosphatase that acts on various phosphoinositides, including phosphatidylinositol 4-phosphate, phosphatidylinositol (4,5)-bisphosphate and phosphatidylinositol (3,4,5)-trisphosphate. Has a role in clathrin-mediated endocytosis. Hydrolyzes PIP2 bound to actin regulatory proteins resulting in the rearrangement of actin filaments downstream of tyrosine kinase and ASH/GRB2., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.1.3.56;3.1.3.36;3.1.3.86;3.1.3.-;3.1.3.95", "go_molecular_function": "GO:0003723 RNA binding;GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity;GO:0004438 phosphatidylinositol-3-phosphate phosphatase activity;GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity;GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity", "go_cellular_component": "GO:0048471 perinuclear region of cytoplasm;GO:0098793 presynapse", "go_biological_process": "GO:0006897 endocytosis;GO:0046856 phosphatidylinositol dephosphorylation;GO:0007612 learning;GO:0048488 synaptic vesicle endocytosis;GO:1904980 positive regulation of endosome organization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MIH5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1LM24-1", "uniprot_id": "A0A3Q1LM24_BOVIN", "mass": 58813.0, "length": 511, "protein_name": "Tripartite motif containing 5", "gene_name": "TRIM5", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "TRIM5", "gene_names_refseq": "", "protein_names_uniprotkb": "Tripartite motif containing 5", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0019901 protein kinase binding;GO:0042803 protein homodimerization activity;GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0046596 regulation of viral entry into host cell;GO:0045087 innate immune response;GO:0032880 regulation of protein localization;GO:0043123 positive regulation of canonical NF-kappaB signal transduction;GO:0010468 regulation of gene expression", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1LM24-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1LU01-1", "uniprot_id": "A0A3Q1LU01_BOVIN", "mass": 57598.0, "length": 512, "protein_name": "Centrosomal protein CCDC61", "gene_name": "CCDC61", "organism": "Bovine", "refseq_name": "centrosomal protein CCDC61 isoform X3", "refseq_ac": "XP_002695221", "gene_names_uniprotkb": "CCDC61", "gene_names_refseq": "CCDC61", "protein_names_uniprotkb": "Centrosomal protein CCDC61; Coiled-coil domain-containing protein 61; VFL3 homolog", "protein_names_refseq": "centrosomal protein CCDC61 isoform X3", "tax_id": 9913, "disease": "", "pathway": " (bta:515425)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008017 microtubule binding;GO:0042802 identical protein binding", "go_cellular_component": "GO:0034451 centriolar satellite;GO:0036064 ciliary basal body;GO:0120103 centriolar subdistal appendage", "go_biological_process": "GO:0090307 mitotic spindle assembly;GO:0098534 centriole assembly", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1LU01-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1LM61-1", "uniprot_id": "A0A3Q1LM61_BOVIN", "mass": 99395.0, "length": 889, "protein_name": "Serine/threonine-protein kinase N3", "gene_name": "PKN3", "organism": "Bovine", "refseq_name": "serine/threonine-protein kinase N3", "refseq_ac": "NP_001192495", "gene_names_uniprotkb": "PKN3", "gene_names_refseq": "PKN3", "protein_names_uniprotkb": "Serine/threonine-protein kinase N3; 2.7.11.13; Protein kinase PKN-beta; Protein-kinase C-related kinase 3", "protein_names_refseq": "serine/threonine-protein kinase N3", "tax_id": 9913, "disease": "", "pathway": " (bta:505353); (R-BTA-5625740); (R-BTA-8980692); (R-BTA-9013106)", "pathway_count": 4, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Contributes to invasiveness in malignant prostate cancer., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.11.1;2.7.11.25;2.7.11.24;3.1.4.4;2.7.11.22;2.7.11.13;2.7.11.23;2.7.12.1;2.7.12.2;2.7.11.17;2.7.11.39;2.7.10.2;2.7.1.150;2.7.11.12;2.7.11.31;2.7.11.26;2.7.11.21;2.7.1.153;2.7.1.137;2.7.1.154;1.14.14.18;4.1.1.32;2.7.11.38;2.7.11.11;3.1.11.-;2.7.4.6;2.7.13.3;2.7.4.18;3.1.24.-;3.6.5.2;2.7.11.-;2.7.11.4;2.7.2.3;3.6.4.-;2.7.11.10", "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0031267 small GTPase binding;GO:0004697 diacylglycerol-dependent serine/threonine kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "GO:0010631 epithelial cell migration;GO:0035556 intracellular signal transduction;GO:0007165 signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1LM61-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1LM89-1", "uniprot_id": "A0A3Q1LM89_BOVIN", "mass": 84307.0, "length": 779, "protein_name": "Metalloprotease TIKI", "gene_name": "TRABD2B", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "TRABD2B", "gene_names_refseq": "", "protein_names_uniprotkb": "Metalloprotease TIKI; 3.4.-.-; TRAB domain-containing protein 2", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Metalloprotease that acts as a negative regulator of the Wnt signaling pathway by mediating the cleavage of the N-terminal residues of a subset of Wnt proteins. Following cleavage, Wnt proteins become oxidized and form large disulfide-bond oligomers, leading to their inactivation., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004222 metalloendopeptidase activity;GO:0046872 metal ion binding;GO:0017147 Wnt-protein binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0031090 organelle membrane", "go_biological_process": "GO:0006508 proteolysis;GO:0031334 positive regulation of protein-containing complex assembly;GO:0016055 Wnt signaling pathway;GO:0030178 negative regulation of Wnt signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1LM89-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1LM90-1", "uniprot_id": "A0A3Q1LM90_BOVIN", "mass": 134113.0, "length": 1177, "protein_name": "Phospholipid-transporting ATPase", "gene_name": "ATP11B", "organism": "Bovine", "refseq_name": "phospholipid-transporting ATPase IF isoform X1", "refseq_ac": "XP_002684944", "gene_names_uniprotkb": "ATP11B", "gene_names_refseq": "ATP11B", "protein_names_uniprotkb": "Phospholipid-transporting ATPase; 7.6.2.1", "protein_names_refseq": "phospholipid-transporting ATPase IF isoform X1", "tax_id": 9913, "disease": "", "pathway": " (bta:614392); (R-BTA-6798695); (R-BTA-936837)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids, phosphatidylserines (PS) and phosphatidylethanolamines (PE), from the outer to the inner leaflet of intracellular membranes. May contribute to the maintenance of membrane lipid asymmetry in endosome compartment., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.5.1.92;7.6.2.1;3.6.5.2;3.2.1.25;3.4.16.2;3.1.3.5;3.1.3.2;3.1.3.48;2.5.1.18;2.4.1.-;2.4.1.275;2.4.1.22;2.4.1.38;2.4.1.90;3.2.1.20;3.4.23.-", "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0090556 phosphatidylserine floppase activity;GO:0140326 ATPase-coupled intramembrane lipid transporter activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0031901 early endosome membrane;GO:0055038 recycling endosome membrane;GO:0005769 early endosome", "go_biological_process": "GO:0015914 phospholipid transport;GO:0045332 phospholipid translocation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1LM90-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1LMB9-1", "uniprot_id": "A0A3Q1LMB9_BOVIN", "mass": 98302.0, "length": 883, "protein_name": "[histone H4]-N-methyl-L-lysine20 N-methyltransferase KMT5B", "gene_name": "KMT5B", "organism": "Bovine", "refseq_name": "histone-lysine N-methyltransferase KMT5B isoform X2", "refseq_ac": "XP_005227253", "gene_names_uniprotkb": "KMT5B", "gene_names_refseq": "KMT5B; 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(R-BTA-2132295); (R-BTA-2467813); (R-BTA-2500257); (R-BTA-3371497); (R-BTA-5620924); (R-BTA-6807878); (R-BTA-6811436); (R-BTA-9013407); (R-BTA-9646399); (R-BTA-9648025)", "pathway_count": 11, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.6.5.2;3.6.5.5;3.6.5.-;3.6.5.3;2.7.11.1;3.6.1.5;3.6.1.15;3.6.5.4", "go_molecular_function": "GO:0005200 structural constituent of cytoskeleton;GO:0005525 GTP binding;GO:0016787 hydrolase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005874 microtubule", "go_biological_process": "GO:0000278 mitotic cell cycle;GO:0030182 neuron differentiation;GO:0000226 microtubule cytoskeleton organization;GO:0007017 microtubule-based process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1LQR2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1LQV7-1", "uniprot_id": "A0A3Q1LQV7_BOVIN", "mass": 45311.0, "length": 409, "protein_name": "RING-type E3 ubiquitin transferase", "gene_name": "MARCHF4", "organism": "Bovine", "refseq_name": "E3 ubiquitin-protein ligase MARCHF4", "refseq_ac": "NP_001192420", "gene_names_uniprotkb": "MARCHF4", "gene_names_refseq": "MARCH4; MARCHF4", "protein_names_uniprotkb": "RING-type E3 ubiquitin transferase; 2.3.2.27", "protein_names_refseq": "E3 ubiquitin-protein ligase MARCHF4; membrane-associated ring finger (C3HC4) 4, E3 ubiquitin protein ligase", "tax_id": 9913, "disease": "", "pathway": " (bta:527624)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity;GO:0004842 ubiquitin-protein transferase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005795 Golgi stack;GO:0005802 trans-Golgi network", "go_biological_process": "GO:0016567 protein ubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1LQV7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1LR63-1", "uniprot_id": "A0A3Q1LR63_BOVIN", "mass": 99619.0, "length": 924, "protein_name": "Hexokinase-3", "gene_name": "HK3", "organism": "Bovine", "refseq_name": "hexokinase-3", "refseq_ac": "NP_001359046", "gene_names_uniprotkb": "HK3", "gene_names_refseq": "HK3", "protein_names_uniprotkb": "Hexokinase-3; 2.7.1.1; Hexokinase type III; Hexokinase-C", "protein_names_refseq": "hexokinase 3 (white cell); hexokinase-3", "tax_id": 9913, "disease": "", "pathway": " (bta:510616); (R-BTA-6798695); (R-BTA-70171)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalyzes the phosphorylation of hexose, such as D-glucose and D-fructose, to hexose 6-phosphate (D-glucose 6-phosphate and D-fructose 6-phosphate, respectively). Mediates the initial step of glycolysis by catalyzing phosphorylation of D-glucose to D-glucose 6-phosphate., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.1.1.42;2.5.1.18;2.7.1.1;2.7.11.24;3.2.1.23;2.4.2.1;5.2.1.8;4.1.2.13;3.6.1.6;2.3.2.27;2.7.1.-;3.1.6.14;3.6.4.13;1.1.1.205;2.7.1.11;2.7.11.22;2.7.11.23;2.3.2.26;2.4.1.25;3.2.1.33;4.2.99.18;5.6.2.4;3.6.4.12;3.4.23.5;1.13.11.34;1.13.11.12;3.6.4.6;1.16.3.1;1.11.1.6;3.4.18.1;3.4.22.1;3.6.4.10;3.4.22.27;3.4.24.35;3.6.5.-;3.1.1.47;5.3.2.1;5.3.3.12;3.4.19.1;2.7.1.35;2.4.1.1;3.5.1.23;3.5.1.-;3.4.22.52;2.3.3.8;5.4.2.11;5.4.2.4;3.3.2.6;3.4.11.4;3.4.21.46;2.7.4.6;2.7.13.3;4.1.2.4;5.3.1.9;5.1.3.-;3.6.1.-;2.4.2.7;4.2.1.24", "go_molecular_function": "GO:0004340 glucokinase activity;GO:0008865 fructokinase activity;GO:0019158 mannokinase activity;GO:0005524 ATP binding;GO:0005536 D-glucose binding", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005741 mitochondrial outer membrane;GO:0005829 cytosol", "go_biological_process": "GO:0006006 glucose metabolic process;GO:0001678 intracellular glucose homeostasis;GO:0006096 glycolytic process;GO:0051156 glucose 6-phosphate metabolic process;GO:0019318 hexose metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1LR63-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1LRM6-1", "uniprot_id": "A0A3Q1LRM6_BOVIN", "mass": 52929.0, "length": 467, "protein_name": "Stress-activated protein kinase JNK", "gene_name": "MAPK10", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "MAPK10", "gene_names_refseq": "", "protein_names_uniprotkb": "Stress-activated protein kinase JNK; 2.7.11.24", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, and thus regulates transcriptional activity., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.11.1;2.7.11.25;2.7.11.24;2.7.11.22;2.7.11.13;2.7.11.23;2.7.12.1;2.7.12.2;2.7.11.17;2.7.11.39;2.7.10.2;2.7.1.150;2.7.11.12;2.7.11.31;2.7.11.26;2.7.11.21;2.7.1.153;2.7.1.137;2.7.1.154;4.1.1.32;2.7.11.38;2.7.11.11;3.1.11.-;2.7.4.6;2.7.13.3;2.7.4.18;3.1.24.-;2.7.11.-;2.7.11.4;2.7.2.3;2.7.11.10", "go_molecular_function": "GO:0005524 ATP binding;GO:0004705 JUN kinase activity;GO:0106310 protein serine kinase activity;GO:0004707 MAP kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm", "go_biological_process": "GO:0007254 JNK cascade;GO:0048511 rhythmic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1LRM6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1LSF3-1", "uniprot_id": "A0A3Q1LSF3_BOVIN", "mass": 97005.0, "length": 867, "protein_name": "Xylosyltransferase 2", "gene_name": "XYLT2", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "XYLT2", "gene_names_refseq": "", "protein_names_uniprotkb": "Xylosyltransferase 2; 2.4.2.26; Xylosyltransferase II", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-1971475)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalyzes the first step in the biosynthesis of chondroitin sulfate, heparan sulfate and dermatan sulfate proteoglycans, such as DCN. Transfers D-xylose from UDP-D-xylose to specific serine residues of the core protein., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.4.2.26", "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0030145 manganese ion binding;GO:0030158 protein xylosyltransferase activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005615 extracellular space;GO:0005576 extracellular region", "go_biological_process": "GO:0015012 heparan sulfate proteoglycan biosynthetic process;GO:0050650 chondroitin sulfate proteoglycan biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1LSF3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1LSI0-1", "uniprot_id": "A0A3Q1LSI0_BOVIN", "mass": 36205.0, "length": 324, "protein_name": "Transmembrane protein 59", "gene_name": "LOC787679", "organism": "Bovine", "refseq_name": "transmembrane protein 59-like", "refseq_ac": "XP_010809650", "gene_names_uniprotkb": "LOC787679", "gene_names_refseq": "LOC787679", "protein_names_uniprotkb": "Transmembrane protein 59", "protein_names_refseq": "transmembrane protein 59-like", "tax_id": 9913, "disease": "", "pathway": " (bta:787679)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Acts as a regulator of autophagy in response to S.aureus infection by promoting activation of LC3 (MAP1LC3A, MAP1LC3B or MAP1LC3C). Acts by interacting with ATG16L1, leading to promote a functional complex between LC3 and ATG16L1 and promoting LC3 lipidation and subsequent activation of autophagy. Modulates the O-glycosylation and complex N-glycosylation steps occurring during the Golgi maturation of several proteins such as APP, BACE1, SEAP or PRNP. Inhibits APP transport to the cell surface and further shedding., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005886 plasma membrane;GO:0005764 lysosome;GO:0005765 lysosomal membrane;GO:0031902 late endosome membrane", "go_biological_process": "GO:0006914 autophagy;GO:0010508 positive regulation of autophagy", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1LSI0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1M5L1-1", "uniprot_id": "A0A3Q1M5L1_BOVIN", "mass": 98490.0, "length": 885, "protein_name": "Phosphodiesterase", "gene_name": "PDE8B", "organism": "Bovine", "refseq_name": "high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform X1", "refseq_ac": "XP_024853664", "gene_names_uniprotkb": "PDE8B", "gene_names_refseq": "PDE8B", "protein_names_uniprotkb": "Phosphodiesterase; 3.1.4.-", "protein_names_refseq": "high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform X1", "tax_id": 9913, "disease": "", "pathway": " (bta:107131388); (R-BTA-418555)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in specific signaling in the thyroid gland., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.1.4.-;3.1.4.1;3.6.1.9;3.1.4.17;3.6.1.1;3.6.1.25;3.6.1.14", "go_molecular_function": "GO:0046872 metal ion binding;GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity;GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity;GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity", "go_cellular_component": "", "go_biological_process": "GO:0007165 signal transduction;GO:0006198 cAMP catabolic process;GO:0070374 positive regulation of ERK1 and ERK2 cascade;GO:0141162 negative regulation of cAMP/PKA signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1M5L1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MBH7-1", "uniprot_id": "A0A3Q1MBH7_BOVIN", "mass": 29018.0, "length": 265, "protein_name": "Gamma-secretase subunit APH-1", "gene_name": "APH1A", "organism": "Bovine", "refseq_name": "gamma-secretase subunit APH-1A isoform X1", "refseq_ac": "XP_010801342", "gene_names_uniprotkb": "APH1A", "gene_names_refseq": "APH1A", "protein_names_uniprotkb": "Gamma-secretase subunit APH-1; APH-1", "protein_names_refseq": "gamma-secretase subunit APH-1A isoform X1", "tax_id": 9913, "disease": "", "pathway": " (bta:539247); (R-BTA-1251985); (R-BTA-193692); (R-BTA-205043); (R-BTA-3928665); (R-BTA-9839383)", "pathway_count": 6, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Potential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0019899 enzyme binding;GO:0030674 protein-macromolecule adaptor activity;GO:0061133 endopeptidase activator activity", "go_cellular_component": "GO:0070765 gamma-secretase complex;GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus", "go_biological_process": "GO:0007219 Notch signaling pathway;GO:0016485 protein processing;GO:0006509 membrane protein ectodomain proteolysis;GO:0007220 Notch receptor processing;GO:0031293 membrane protein intracellular domain proteolysis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MBH7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1LTP7-1", "uniprot_id": "A0A3Q1LTP7_BOVIN", "mass": 49738.0, "length": 450, "protein_name": "Neuronal acetylcholine receptor subunit alpha-10", "gene_name": "CHRNA10", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "CHRNA10", "gene_names_refseq": "", "protein_names_uniprotkb": "Neuronal acetylcholine receptor subunit alpha-10; Nicotinic acetylcholine receptor subunit alpha-10", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.11.1;1.8.-.-", "go_molecular_function": "GO:0005262 calcium channel activity;GO:0022848 acetylcholine-gated monoatomic cation-selective channel activity;GO:0022850 serotonin-gated monoatomic cation channel activity;GO:1904315 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential;GO:0005231 excitatory extracellular ligand-gated monoatomic ion channel activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0045202 synapse;GO:0045211 postsynaptic membrane;GO:0043005 neuron projection;GO:1902495 transmembrane transporter complex", "go_biological_process": "GO:0042391 regulation of membrane potential;GO:0050910 detection of mechanical stimulus involved in sensory perception of sound;GO:0007268 chemical synaptic transmission;GO:0034220 monoatomic ion transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1LTP7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1LTX1-1", "uniprot_id": "A0A3Q1LTX1_BOVIN", "mass": 47390.0, "length": 439, "protein_name": "ADP/ATP translocase", "gene_name": "SLC25A6", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "SLC25A6", "gene_names_refseq": "", "protein_names_uniprotkb": "ADP/ATP translocase; ADP,ATP carrier protein", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalyzes the exchange of ADP and ATP across the membrane., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005471 ATP:ADP antiporter activity", "go_cellular_component": "GO:0005743 mitochondrial inner membrane;GO:0005757 mitochondrial permeability transition pore complex", "go_biological_process": "GO:0046902 regulation of mitochondrial membrane permeability;GO:0140021 mitochondrial ADP transmembrane transport;GO:1990544 mitochondrial ATP transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1LTX1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MHE5-1", "uniprot_id": "A0A3Q1MHE5_BOVIN", "mass": 56572.0, "length": 529, "protein_name": "Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial", "gene_name": "DLST", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "DLST", "gene_names_refseq": "", "protein_names_uniprotkb": "Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial; 2-oxoglutarate dehydrogenase complex component E2; 2.3.1.61; Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex; E2K", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-6783984); (R-BTA-9853506); (R-BTA-9857492); (R-BTA-9858328)", "pathway_count": 4, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Dihydrolipoamide succinyltransferase (E2) component of the 2-oxoglutarate dehydrogenase complex. The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). The 2-oxoglutarate dehydrogenase complex is mainly active in the mitochondrion. A fraction of the 2-oxoglutarate dehydrogenase complex also localizes in the nucleus and is required for lysine succinylation of histones: associates with KAT2A on chromatin and provides succinyl-CoA to histone succinyltransferase KAT2A., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.3.1.61;1.8.1.4;2.3.1.-;2.3.1.200;2.3.1.168;1.2.4.2", "go_molecular_function": "GO:0004149 dihydrolipoyllysine-residue succinyltransferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005759 mitochondrial matrix;GO:0045252 oxoglutarate dehydrogenase complex;GO:0005654 nucleoplasm;GO:0005739 mitochondrion", "go_biological_process": "GO:0006099 tricarboxylic acid cycle;GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine;GO:0120551 2-oxoglutarate decarboxylation to succinyl-CoA", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MHE5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1LU60-1", "uniprot_id": "A0A3Q1LU60_BOVIN", "mass": 229021.0, "length": 2054, "protein_name": "histone acetyltransferase", "gene_name": "KAT6B", "organism": "Bovine", "refseq_name": "histone acetyltransferase KAT6B isoform X1", "refseq_ac": "XP_002698931", "gene_names_uniprotkb": "KAT6B", "gene_names_refseq": "KAT6B", "protein_names_uniprotkb": "histone acetyltransferase; 2.3.1.48", "protein_names_refseq": "histone acetyltransferase KAT6B isoform X1", "tax_id": 9913, "disease": "", "pathway": " (bta:535403); (R-BTA-3214847)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.3.1.48;2.3.1.-;2.3.1.259", "go_molecular_function": "GO:0003677 DNA binding;GO:0003682 chromatin binding;GO:0003713 transcription coactivator activity;GO:0008270 zinc ion binding;GO:0003712 transcription coregulator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0000785 chromatin;GO:0070776 MOZ/MORF histone acetyltransferase complex;GO:0000786 nucleosome", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0045892 negative regulation of DNA-templated transcription;GO:0006334 nucleosome assembly;GO:0006355 regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1LU60-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1LUB3-1", "uniprot_id": "A0A3Q1LUB3_BOVIN", "mass": 31340.0, "length": 283, "protein_name": "S-methyl-5'-thioadenosine phosphorylase", "gene_name": "MTAP", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "MTAP", "gene_names_refseq": "", "protein_names_uniprotkb": "S-methyl-5'-thioadenosine phosphorylase; 2.4.2.28; 5'-methylthioadenosine phosphorylase; MTA phosphorylase; MTAPase; MTAP", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates., [UniProtKB, HAMAP, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.4.2.28;3.5.4.4;2.4.2.1", "go_molecular_function": "GO:0017061 S-methyl-5-thioadenosine phosphorylase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol", "go_biological_process": "GO:0006166 purine ribonucleoside salvage;GO:0019509 L-methionine salvage from methylthioadenosine", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1LUB3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1LUF0-1", "uniprot_id": "A0A3Q1LUF0_BOVIN", "mass": 131357.0, "length": 1181, "protein_name": "AT-rich interactive domain-containing protein 5B", "gene_name": "ARID5B", "organism": "Bovine", "refseq_name": "AT-rich interactive domain-containing protein 5B isoform X1", "refseq_ac": "XP_024842616", "gene_names_uniprotkb": "ARID5B", "gene_names_refseq": "ARID5B", "protein_names_uniprotkb": "AT-rich interactive domain-containing protein 5B", "protein_names_refseq": "AT-rich interactive domain-containing protein 5B isoform X1", "tax_id": 9913, "disease": "", "pathway": " (bta:783538); (R-BTA-3214842)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003713 transcription coactivator activity;GO:0000976 transcription cis-regulatory region binding;GO:0003677 DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006357 regulation of transcription by RNA polymerase II;GO:0060612 adipose tissue development;GO:0045815 transcription initiation-coupled chromatin remodeling;GO:0006351 DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1LUF0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1LUQ3-1", "uniprot_id": "A0A3Q1LUQ3_BOVIN", "mass": 47147.0, "length": 451, "protein_name": "Transcription factor SOX", "gene_name": "SOX11", "organism": "Bovine", "refseq_name": "transcription factor SOX-11", "refseq_ac": "XP_024855327", "gene_names_uniprotkb": "SOX11", "gene_names_refseq": "SOX11", "protein_names_uniprotkb": "Transcription factor SOX", "protein_names_refseq": "transcription factor SOX-11", "tax_id": 9913, "disease": "", "pathway": " (bta:107132954)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0007420 brain development;GO:0030182 neuron differentiation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1LUQ3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1LUU0-1", "uniprot_id": "A0A3Q1LUU0_BOVIN", "mass": 107711.0, "length": 948, "protein_name": "Type II inositol 1,4,5-trisphosphate 5-phosphatase", "gene_name": "INPP5B", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "INPP5B", "gene_names_refseq": "", "protein_names_uniprotkb": "Type II inositol 1,4,5-trisphosphate 5-phosphatase; 3.1.3.36; 3.1.3.56; Phosphoinositide 5-phosphatase", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-1855183); (R-BTA-1855204)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Regulates phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) cellular levels by cleaving the phosphate at the 5-position producing PtdIns(4)P. Also hydrolyzes the 5-position phosphate from inositol 1,4,5-trisphosphate (Ins(1,4,5)P3), thereby modulating cellular signaling events., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.1.3.56;3.1.3.36;3.1.3.86;3.1.3.-;3.1.3.95", "go_molecular_function": "GO:0046872 metal ion binding;GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity;GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity", "go_cellular_component": "GO:0005829 cytosol;GO:0030670 phagocytic vesicle membrane;GO:0031901 early endosome membrane;GO:0005793 endoplasmic reticulum-Golgi intermediate compartment;GO:0005737 cytoplasm", "go_biological_process": "GO:0007165 signal transduction;GO:0046856 phosphatidylinositol dephosphorylation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1LUU0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1LUZ8-1", "uniprot_id": "A0A3Q1LUZ8_BOVIN", "mass": 96380.0, "length": 861, "protein_name": "DNA topoisomerase", "gene_name": "TOP3B", "organism": "Bovine", "refseq_name": "DNA topoisomerase 3-beta-1", "refseq_ac": "NP_001193635", "gene_names_uniprotkb": "TOP3B", "gene_names_refseq": "TOP3B", "protein_names_uniprotkb": "DNA topoisomerase; 5.6.2.1", "protein_names_refseq": "DNA topoisomerase 3-beta-1; topoisomerase (DNA) III beta", "tax_id": 9913, "disease": "", "pathway": " (bta:537418)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand., [UniProtKB, UniProtKB, UniProtKB]; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand than undergoes passage around the unbroken strand thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone. Possesses negatively supercoiled DNA relaxing activity., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0003917 DNA topoisomerase type I (single strand cut, ATP-independent) activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006281 DNA repair;GO:0006310 DNA recombination;GO:0006265 DNA topological change", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1LUZ8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1M337-1", "uniprot_id": "A0A3Q1M337_BOVIN", "mass": 88252.0, "length": 784, "protein_name": "Nucleoporin NDC1", "gene_name": "NDC1", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "NDC1", "gene_names_refseq": "", "protein_names_uniprotkb": "Nucleoporin NDC1; Transmembrane protein 48", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-159227); (R-BTA-159230); (R-BTA-159231); (R-BTA-159236); (R-BTA-1855170); (R-BTA-1855196); (R-BTA-1855229); (R-BTA-191859); (R-BTA-3108214); (R-BTA-3232142); (R-BTA-3301854); (R-BTA-3371453); (R-BTA-4085377); (R-BTA-4551638); (R-BTA-4570464); (R-BTA-4615885); (R-BTA-9615933)", "pathway_count": 17, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of the nuclear pore complex (NPC), which plays a key role in de novo assembly and insertion of NPC in the nuclear envelope. Required for NPC and nuclear envelope assembly, possibly by forming a link between the nuclear envelope membrane and soluble nucleoporins, thereby anchoring the NPC in the membrane., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0017056 structural constituent of nuclear pore;GO:0030674 protein-macromolecule adaptor activity", "go_cellular_component": "GO:0005643 nuclear pore;GO:0031965 nuclear membrane;GO:0005737 cytoplasm;GO:0070762 nuclear pore transmembrane ring", "go_biological_process": "GO:0015031 protein transport;GO:0051028 mRNA transport;GO:0051292 nuclear pore complex assembly;GO:0051664 nuclear pore localization;GO:0006999 nuclear pore organization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1M337-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1LVF3-1", "uniprot_id": "A0A3Q1LVF3_BOVIN", "mass": 199450.0, "length": 1729, "protein_name": "Transcription elongation factor SPT6", "gene_name": "SUPT6H", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "SUPT6H", "gene_names_refseq": "", "protein_names_uniprotkb": "Transcription elongation factor SPT6; Transcription elongation factor spt6", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Histone H3-H4 chaperone that plays a key role in the regulation of transcription elongation and mRNA processing. Enhances the transcription elongation by RNA polymerase II (RNAPII) and is also required for the efficient activation of transcriptional elongation by the HIV-1 nuclear transcriptional activator, Tat. Besides chaperoning histones in transcription, acts to transport and splice mRNA by forming a complex with IWS1 and the C-terminal domain (CTD) of the RNAPII subunit RPB1 (POLR2A). The SUPT6H:IWS1:CTD complex recruits mRNA export factors (ALYREF/THOC4, EXOSC10) as well as histone modifying enzymes (such as SETD2), to ensure proper mRNA splicing, efficient mRNA export and elongation-coupled H3K36 methylation, a signature chromatin mark of active transcription. SUPT6H via its association with SETD1A, regulates both class-switch recombination and somatic hypermutation through formation of H3K4me3 epigenetic marks on activation-induced cytidine deaminase (AICDA) target loci. Promotes the activation of the myogenic gene program by entailing erasure of the repressive H3K27me3 epigenetic mark through stabilization of the chromatin interaction of the H3K27 demethylase KDM6A., [UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0042393 histone binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006397 mRNA processing;GO:0008380 RNA splicing;GO:0045191 regulation of isotype switching;GO:0051028 mRNA transport;GO:0051147 regulation of muscle cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1LVF3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1LVP8-1", "uniprot_id": "A0A3Q1LVP8_BOVIN", "mass": 301755.0, "length": 2706, "protein_name": "Teneurin-3", "gene_name": "TENM3", "organism": "Bovine", "refseq_name": "teneurin-3 isoform X1", "refseq_ac": "XP_059738180", "gene_names_uniprotkb": "TENM3", "gene_names_refseq": "ODZ3; TENM3", "protein_names_uniprotkb": "Teneurin-3; Protein Odd Oz/ten-m homolog 3; Tenascin-M3; Teneurin transmembrane protein 3", "protein_names_refseq": "teneurin-3 isoform X1", "tax_id": 9913, "disease": "", "pathway": " (bta:511615)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0042803 protein homodimerization activity;GO:0046982 protein heterodimerization activity;GO:0050839 cell adhesion molecule binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0030424 axon;GO:0043005 neuron projection", "go_biological_process": "GO:0007155 cell adhesion;GO:0007165 signal transduction;GO:0048666 neuron development;GO:0048593 camera-type eye morphogenesis;GO:0030154 cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1LVP8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1LVR6-1", "uniprot_id": "A0A3Q1LVR6_BOVIN", "mass": 32925.0, "length": 315, "protein_name": "Forkhead box E3", "gene_name": "FOXE3", "organism": "Bovine", "refseq_name": "forkhead box protein E3", "refseq_ac": "NP_001193251", "gene_names_uniprotkb": "FOXE3", "gene_names_refseq": "FOXE3", "protein_names_uniprotkb": "Forkhead box E3", "protein_names_refseq": "forkhead box protein E3", "tax_id": 9913, "disease": "", "pathway": " (bta:787258)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005667 transcription regulator complex", "go_biological_process": "GO:0002930 trabecular meshwork development;GO:0006357 regulation of transcription by RNA polymerase II;GO:0030154 cell differentiation;GO:0043066 negative regulation of apoptotic process;GO:0042789 mRNA transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1LVR6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1M9W0-1", "uniprot_id": "A0A3Q1M9W0_BOVIN", "mass": 41657.0, "length": 384, "protein_name": "N-myc downstream regulated 1", "gene_name": "NDRG1", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "NDRG1", "gene_names_refseq": "", "protein_names_uniprotkb": "N-myc downstream regulated 1", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (bta:504499)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes. May be involved in neuron differentiation., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008017 microtubule binding;GO:0045296 cadherin binding;GO:0031267 small GTPase binding;GO:0016151 nickel cation binding;GO:0043015 gamma-tubulin binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005634 nucleus;GO:0005813 centrosome;GO:0005829 cytosol;GO:0005874 microtubule", "go_biological_process": "GO:0007165 signal transduction;GO:0007399 nervous system development;GO:0030154 cell differentiation;GO:0016055 Wnt signaling pathway;GO:0008285 negative regulation of cell population proliferation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1M9W0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1LWL1-1", "uniprot_id": "A0A3Q1LWL1_BOVIN", "mass": 32535.0, "length": 327, "protein_name": "Oligodendrocyte transcription factor 2", "gene_name": "OLIG2", "organism": "Bovine", "refseq_name": "oligodendrocyte transcription factor 2", "refseq_ac": "XP_024849412", "gene_names_uniprotkb": "OLIG2", "gene_names_refseq": "OLIG2", "protein_names_uniprotkb": "Oligodendrocyte transcription factor 2", "protein_names_refseq": "oligodendrocyte transcription factor 2", "tax_id": 9913, "disease": "", "pathway": " (bta:539695)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0042802 identical protein binding;GO:0046983 protein dimerization activity;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0071837 HMG box domain binding;GO:0070888 E-box binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0042552 myelination;GO:0061564 axon development;GO:0021778 oligodendrocyte cell fate specification", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1LWL1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1LWN6-1", "uniprot_id": "A0A3Q1LWN6_BOVIN", "mass": 228406.0, "length": 1979, "protein_name": "Myosin-11", "gene_name": "CEP20; MYH11", "organism": "Bovine", "refseq_name": "myosin-11 isoform X1", "refseq_ac": "XP_024840730", "gene_names_uniprotkb": "CEP20; MYH11; CEP20", "gene_names_refseq": "MYH11", "protein_names_uniprotkb": "Myosin-11; Myosin heavy chain 11; Myosin heavy chain, smooth muscle isoform; SMMHC", "protein_names_refseq": "myosin-11 isoform X1", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Involved in the biogenesis of cilia. Required for the recruitment of PLK1 to centrosomes and S phase progression., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Muscle contraction., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005516 calmodulin binding;GO:0005524 ATP binding;GO:0051015 actin filament binding;GO:0008307 structural constituent of muscle;GO:0003774 cytoskeletal motor activity", "go_cellular_component": "GO:0005859 muscle myosin complex;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0042470 melanosome;GO:0032982 myosin filament", "go_biological_process": "GO:0008360 regulation of cell shape;GO:0055013 cardiac muscle cell development;GO:0048251 elastic fiber assembly;GO:0030030 cell projection organization;GO:0034453 microtubule anchoring", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1LWN6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1LX04-1", "uniprot_id": "A0A3Q1LX04_BOVIN", "mass": 33998.0, "length": 314, "protein_name": "Transcription factor SOX", "gene_name": "SOX12", "organism": "Bovine", "refseq_name": "transcription factor SOX-12", "refseq_ac": "XP_010809935", "gene_names_uniprotkb": "SOX12", "gene_names_refseq": "SOX12", "protein_names_uniprotkb": "Transcription factor SOX", "protein_names_refseq": "transcription factor SOX-12", "tax_id": 9913, "disease": "", "pathway": " (bta:101905202)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0032993 protein-DNA complex", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0021510 spinal cord development;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0007420 brain development", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1LX04-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1LXB8-1", "uniprot_id": "A0A3Q1LXB8_BOVIN", "mass": 99505.0, "length": 938, "protein_name": "E3 ubiquitin-protein ligase ZNRF3", "gene_name": "ZNRF3", "organism": "Bovine", "refseq_name": "E3 ubiquitin-protein ligase ZNRF3", "refseq_ac": "XP_024833583", "gene_names_uniprotkb": "ZNRF3", "gene_names_refseq": "ZNRF3", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase ZNRF3; 2.3.2.27; RING-type E3 ubiquitin transferase ZNRF3; Zinc/RING finger protein 3", "protein_names_refseq": "E3 ubiquitin-protein ligase ZNRF3", "tax_id": 9913, "disease": "", "pathway": " (bta:535441)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination and subsequent degradation of Wnt receptor complex components Frizzled and LRP6. Acts on both canonical and non-canonical Wnt signaling pathway. Acts as a tumor suppressor in the intestinal stem cell zone by inhibiting the Wnt signaling pathway, thereby restricting the size of the intestinal stem cell zone. Along with RSPO2 and RNF43, constitutes a master switch that governs limb specification., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005109 frizzled binding;GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:2000095 regulation of Wnt signaling pathway, planar cell polarity pathway;GO:0090090 negative regulation of canonical Wnt signaling pathway;GO:0016055 Wnt signaling pathway;GO:0016567 protein ubiquitination;GO:0006511 ubiquitin-dependent protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1LXB8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1LXH4-1", "uniprot_id": "A0A3Q1LXH4_BOVIN", "mass": 35850.0, "length": 340, "protein_name": "Ephrin-B3", "gene_name": "EFNB3", "organism": "Bovine", "refseq_name": "ephrin-B3 precursor", "refseq_ac": "NP_001193212", "gene_names_uniprotkb": "EFNB3", "gene_names_refseq": "EFNB3", "protein_names_uniprotkb": "Ephrin-B3", "protein_names_refseq": "ephrin-B3 precursor", "tax_id": 9913, "disease": "", "pathway": " (bta:617714); (R-BTA-2682334); (R-BTA-3928662); (R-BTA-3928664); (R-BTA-3928665)", "pathway_count": 5, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. May play a pivotal role in forebrain function. Binds to, and induce the collapse of, commissural axons/growth cones in vitro. May play a role in constraining the orientation of longitudinally projecting axons., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0046875 ephrin receptor binding", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0005886 plasma membrane;GO:0042734 presynaptic membrane;GO:0098686 hippocampal mossy fiber to CA3 synapse", "go_biological_process": "GO:0048013 ephrin receptor signaling pathway;GO:0007411 axon guidance;GO:0050771 negative regulation of axonogenesis;GO:0099557 trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1LXH4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1LXW0-1", "uniprot_id": "A0A3Q1LXW0_BOVIN", "mass": 122553.0, "length": 1126, "protein_name": "E3 ubiquitin-protein ligase TRIM33", "gene_name": "TRIM33", "organism": "Bovine", "refseq_name": "E3 ubiquitin-protein ligase TRIM33", "refseq_ac": "NP_001192947", "gene_names_uniprotkb": "TRIM33", "gene_names_refseq": "TRIM33", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase TRIM33; 2.3.2.27; Ectodermin homolog; RING-type E3 ubiquitin transferase TRIM33; Transcription intermediary factor 1-gamma; Tripartite motif-containing protein 33", "protein_names_refseq": "E3 ubiquitin-protein ligase TRIM33", "tax_id": 9913, "disease": "", "pathway": " (bta:533296); (R-BTA-2173795)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.3.2.27", "go_molecular_function": "GO:0070410 co-SMAD binding;GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity;GO:0070412 R-SMAD binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0000785 chromatin", "go_biological_process": "GO:0017015 regulation of transforming growth factor beta receptor signaling pathway;GO:0006351 DNA-templated transcription;GO:0030514 negative regulation of BMP signaling pathway;GO:0016567 protein ubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1LXW0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1LXZ6-1", "uniprot_id": "A0A3Q1LXZ6_BOVIN", "mass": 20402.0, "length": 193, "protein_name": "BCL2 binding component 3", "gene_name": "BBC3", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "BBC3", "gene_names_refseq": "", "protein_names_uniprotkb": "BCL2 binding component 3", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0070245 positive regulation of thymocyte apoptotic process;GO:0071456 cellular response to hypoxia;GO:0006974 DNA damage response;GO:0031334 positive regulation of protein-containing complex assembly;GO:0097194 execution phase of apoptosis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1LXZ6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MJ94-1", "uniprot_id": "A0A3Q1MJ94_BOVIN", "mass": 70643.0, "length": 619, "protein_name": "Neutral amino acid transporter 9", "gene_name": "SLC38A9", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "SLC38A9", "gene_names_refseq": "", "protein_names_uniprotkb": "Neutral amino acid transporter 9; Solute carrier family 38 member 9", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-1632852); (R-BTA-165159); (R-BTA-166208); (R-BTA-380972); (R-BTA-5628897); (R-BTA-8943724); (R-BTA-9639288)", "pathway_count": 7, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0015179 L-amino acid transmembrane transporter activity;GO:0046872 metal ion binding;GO:0015485 cholesterol binding;GO:0005085 guanyl-nucleotide exchange factor activity;GO:0015186 L-glutamine transmembrane transporter activity", "go_cellular_component": "GO:0005765 lysosomal membrane;GO:0031902 late endosome membrane;GO:0071986 Ragulator complex;GO:1990877 FNIP-folliculin RagC/D GAP", "go_biological_process": "GO:0003333 amino acid transmembrane transport;GO:1904263 positive regulation of TORC1 signaling;GO:0071230 cellular response to amino acid stimulus;GO:0006865 amino acid transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MJ94-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1LZ03-1", "uniprot_id": "A0A3Q1LZ03_BOVIN", "mass": 51734.0, "length": 454, "protein_name": "unspecific monooxygenase", "gene_name": "CYP3A24", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "CYP3A24", "gene_names_refseq": "", "protein_names_uniprotkb": "unspecific monooxygenase; 1.14.14.1", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-211945); (R-BTA-211958); (R-BTA-211981); (R-BTA-5423646); (R-BTA-9027307); (R-BTA-9749641); (R-BTA-9754706); (R-BTA-9757110)", "pathway_count": 8, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.14.14.1;1.14.13.n7;1.14.14.-", "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen;GO:0050649 testosterone 6-beta-hydroxylase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0070989 oxidative demethylation;GO:0008202 steroid metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1LZ03-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1LZ20-1", "uniprot_id": "A0A3Q1LZ20_BOVIN", "mass": 22088.0, "length": 186, "protein_name": "Interferon, beta 3", "gene_name": "LOC112447878", "organism": "Bovine", "refseq_name": "interferon beta-3", "refseq_ac": "XP_059745362", "gene_names_uniprotkb": "LOC112447878; LOC100848709; LOC112441480; LOC112447877; LOC112447879; LOC112447880", "gene_names_refseq": "LOC112447880", "protein_names_uniprotkb": "Interferon, beta 3", "protein_names_refseq": "interferon beta-3", "tax_id": 9913, "disease": "", "pathway": " (bta:112447880); (R-BTA-909733); (R-BTA-912694)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005125 cytokine activity;GO:0005132 type I interferon receptor binding", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0002312 B cell activation involved in immune response;GO:0071359 cellular response to dsRNA;GO:0051607 defense response to virus;GO:0060337 type I interferon-mediated signaling pathway;GO:0002250 adaptive immune response", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1LZ20-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1M0A4-1", "uniprot_id": "A0A3Q1M0A4_BOVIN", "mass": 137342.0, "length": 1220, "protein_name": "Cation-transporting ATPase", "gene_name": "ATP13A5", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "ATP13A5", "gene_names_refseq": "", "protein_names_uniprotkb": "Cation-transporting ATPase; 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May be involved in Mg(2+) transport., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, 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TNF and IL6 levels were also decreased while those of NAMPT were unaffected., [RefSeq, PubMed]; The presence of 35bp-insertion in visfatin gene may influence the birth weight and bodyweight in 6-month-old cows., [RefSeq, PubMed]; These results indicate that mammary epithelial cells express the visfatin protein and secrete them into the milk., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.4.2.12", "go_molecular_function": "GO:0047280 nicotinamide phosphoribosyltransferase activity;GO:0042802 identical protein binding;GO:0005125 cytokine activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005759 mitochondrial matrix;GO:0005829 cytosol", "go_biological_process": "GO:0009435 NAD+ biosynthetic process;GO:0032922 circadian regulation of gene expression;GO:0048511 rhythmic process;GO:0006741 NADP+ biosynthetic process;GO:0006954 inflammatory response", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A3Q1M241-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1M294-1", "uniprot_id": "A0A3Q1M294_BOVIN", "mass": 53970.0, "length": 471, "protein_name": "Kynurenine 3-monooxygenase", "gene_name": "KMO", "organism": "Bovine", "refseq_name": "kynurenine 3-monooxygenase", "refseq_ac": "NP_001230227", "gene_names_uniprotkb": "KMO", "gene_names_refseq": "KMO", "protein_names_uniprotkb": "Kynurenine 3-monooxygenase; 1.14.13.9; Kynurenine 3-hydroxylase", "protein_names_refseq": "kynurenine 3-monooxygenase (kynurenine 3-hydroxylase); kynurenine 3-monooxygenase", "tax_id": 9913, "disease": "", "pathway": " (bta:515996); (R-BTA-71240)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract., [UniProtKB, HAMAP, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, 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hydrocarbon receptor complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0051775 response to redox state;GO:0032922 circadian regulation of gene expression;GO:0042753 positive regulation of circadian rhythm", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1M2L6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1M2P8-1", "uniprot_id": "A0A3Q1M2P8_BOVIN", "mass": 95983.0, "length": 862, "protein_name": "Epidermal growth factor receptor kinase substrate 8", "gene_name": "EPS8", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "EPS8", "gene_names_refseq": "", "protein_names_uniprotkb": "Epidermal growth factor receptor kinase substrate 8", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (bta:538419)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", 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0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003779 actin binding;GO:0031267 small GTPase binding", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0017146 NMDA selective glutamate receptor complex;GO:0005903 brush border;GO:0005938 cell cortex;GO:0014069 postsynaptic density", "go_biological_process": "GO:0070358 actin polymerization-dependent cell motility;GO:0051016 barbed-end actin filament capping;GO:0051017 actin filament bundle assembly;GO:0016601 Rac protein signal transduction;GO:0008360 regulation of cell shape", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1M2P8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1M2R2-1", "uniprot_id": "A0A3Q1M2R2_BOVIN", "mass": 214166.0, "length": 1929, "protein_name": "Transport and Golgi organization protein 1 homolog", "gene_name": "MIA3", "organism": "Bovine", "refseq_name": "transport and Golgi organization protein 1 homolog isoform X1", "refseq_ac": "XP_024831920", "gene_names_uniprotkb": "MIA3", "gene_names_refseq": "MIA3", "protein_names_uniprotkb": "Transport and Golgi organization protein 1 homolog", "protein_names_refseq": "transport and Golgi organization protein 1 homolog isoform X1", "tax_id": 9913, "disease": "", "pathway": " (bta:509133); (R-BTA-381426); (R-BTA-8957275)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0038024 cargo receptor activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane;GO:0070971 endoplasmic reticulum exit site", "go_biological_process": "GO:0090110 COPII-coated vesicle cargo loading;GO:0042953 lipoprotein transport;GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0009306 protein secretion;GO:0006887 exocytosis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1M2R2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1M2V4-1", "uniprot_id": "A0A3Q1M2V4_BOVIN", "mass": 146735.0, "length": 1325, "protein_name": "Bile salt export pump", "gene_name": "ABCB11", "organism": "Bovine", "refseq_name": "bile salt export pump isoform X1", "refseq_ac": "XP_005202395", "gene_names_uniprotkb": "ABCB11", "gene_names_refseq": "ABCB11", "protein_names_uniprotkb": "Bile salt export pump", "protein_names_refseq": "bile salt export pump isoform X1", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-159418); (R-BTA-193368)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalyzes the transport of the major hydrophobic bile salts, such as taurine and glycine-conjugated cholic acid across the canalicular membrane of hepatocytes in an ATP-dependent manner, therefore participates in hepatic bile acid homeostasis and consequently to lipid homeostasis through regulation of biliary lipid secretion in a bile salts dependent manner. Transports taurine-conjugated bile salts more rapidly than glycine-conjugated bile salts. Also transports non-bile acid compounds, such as pravastatin and fexofenadine in an ATP-dependent manner and may be involved in their biliary excretion., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0008559 ABC-type xenobiotic transporter activity;GO:0015126 canalicular bile acid transmembrane transporter activity;GO:0015432 ABC-type bile acid transporter activity;GO:0016887 ATP hydrolysis activity", "go_cellular_component": "GO:0009986 cell surface;GO:0016324 apical plasma membrane;GO:0046581 intercellular canaliculus;GO:0055038 recycling endosome membrane", "go_biological_process": "GO:0006631 fatty acid metabolic process;GO:0006805 xenobiotic metabolic process;GO:0042632 cholesterol homeostasis;GO:0055091 phospholipid homeostasis;GO:0016567 protein ubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1M2V4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1M334-1", "uniprot_id": "A0A3Q1M334_BOVIN", "mass": 111702.0, "length": 967, "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "STK10", "organism": "Bovine", "refseq_name": "serine/threonine-protein kinase 10", "refseq_ac": "NP_001179556", "gene_names_uniprotkb": "STK10", "gene_names_refseq": "STK10", "protein_names_uniprotkb": "non-specific serine/threonine protein kinase; 2.7.11.1", "protein_names_refseq": "serine/threonine-protein kinase 10", "tax_id": 9913, "disease": "", "pathway": " (bta:526376)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.11.1;2.7.11.25;2.7.11.24;2.7.11.22;2.7.11.13;2.7.11.23;2.7.12.1;2.7.12.2;2.7.11.17;2.7.11.39;2.7.10.2;2.7.1.150;2.7.11.12;2.7.11.31;2.7.11.26;2.7.11.21;2.7.1.153;2.7.1.137;2.7.1.154;4.1.1.32;2.7.11.38;2.7.11.11;3.1.11.-;2.7.4.6;2.7.13.3;2.7.4.18;3.1.24.-;2.7.11.-;2.7.11.4;2.7.2.3;2.7.11.10", "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0042803 protein homodimerization activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0071593 lymphocyte aggregation;GO:2000401 regulation of lymphocyte migration", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1M334-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MEQ8-1", "uniprot_id": "A0A3Q1MEQ8_BOVIN", "mass": 140487.0, "length": 1265, "protein_name": "Methionine synthase", "gene_name": "MTR", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "MTR", "gene_names_refseq": "", "protein_names_uniprotkb": "Methionine synthase; 2.1.1.13; 5-methyltetrahydrofolate--homocysteine methyltransferase", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-156581); (R-BTA-1614635); (R-BTA-9013407); (R-BTA-9759218)", "pathway_count": 4, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalyzes the transfer of a methyl group from methylcob(III)alamin (MeCbl) to homocysteine, yielding enzyme-bound cob(I)alamin and methionine in the cytosol. MeCbl is an active form of cobalamin (vitamin B12) used as a cofactor for methionine biosynthesis. Cob(I)alamin form is regenerated to MeCbl by a transfer of a methyl group from 5-methyltetrahydrofolate. The processing of cobalamin in the cytosol occurs in a multiprotein complex composed of at least MMACHC, MMADHC, MTRR (methionine synthase reductase) and MTR which may contribute to shuttle safely and efficiently cobalamin towards MTR in order to produce methionine., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.11.1;2.1.1.13;2.7.11.39;2.7.10.2;1.16.1.8;3.6.4.6;2.3.1.168;2.3.1.-;2.7.10.4;3.6.5.-;1.16.1.6;2.5.1.151", "go_molecular_function": "GO:0008705 methionine synthase activity;GO:0008270 zinc ion binding;GO:0031419 cobalamin binding", "go_cellular_component": "GO:0005829 cytosol;GO:0005737 cytoplasm", "go_biological_process": "GO:0032259 methylation;GO:0046653 tetrahydrofolate metabolic process;GO:0009086 methionine biosynthetic process;GO:0050667 homocysteine metabolic process;GO:0042558 pteridine-containing compound metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MEQ8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1M376-1", "uniprot_id": "A0A3Q1M376_BOVIN", "mass": 192799.0, "length": 1794, "protein_name": "Neurexin-2", "gene_name": "NRXN2", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "NRXN2", "gene_names_refseq": "", "protein_names_uniprotkb": "Neurexin-2; Neurexin II-alpha; Neurexin-2-alpha", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Neuronal cell surface protein that may be involved in cell recognition and cell adhesion. May mediate intracellular signaling., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004888 transmembrane signaling receptor activity;GO:0046872 metal ion binding;GO:0005246 calcium channel regulator activity;GO:0050839 cell adhesion molecule binding;GO:0097109 neuroligin family protein binding", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0042734 presynaptic membrane;GO:0032991 protein-containing complex", "go_biological_process": "GO:0097116 gephyrin clustering involved in postsynaptic density assembly;GO:0007155 cell adhesion;GO:0007165 signal transduction;GO:0030534 adult behavior;GO:0035176 social behavior", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1M376-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1M407-1", "uniprot_id": "A0A3Q1M407_BOVIN", "mass": 125454.0, "length": 1110, "protein_name": "Centrosomal protein 131", "gene_name": "CEP131", "organism": "Bovine", "refseq_name": "centrosomal protein of 131 kDa isoform X1", "refseq_ac": "XP_005221098", "gene_names_uniprotkb": "CEP131", "gene_names_refseq": "AZI1; CEP131", "protein_names_uniprotkb": "Centrosomal protein 131", "protein_names_refseq": "centrosomal protein of 131 kDa isoform X1", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-2565942); (R-BTA-380259); (R-BTA-380270); (R-BTA-380284); (R-BTA-380320); (R-BTA-5620912); (R-BTA-8854518)", "pathway_count": 7, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0042803 protein homodimerization activity;GO:0044877 protein-containing complex binding", "go_cellular_component": "GO:0005929 cilium;GO:0001669 acrosomal vesicle;GO:0005814 centriole;GO:0034451 centriolar satellite;GO:0036064 ciliary basal body", "go_biological_process": "GO:0035735 intraciliary transport involved in cilium assembly;GO:0010824 regulation of centrosome duplication;GO:0008284 positive regulation of cell population proliferation;GO:0090316 positive regulation of intracellular protein transport;GO:0060271 cilium assembly", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1M407-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1M3I7-1", "uniprot_id": "A0A3Q1M3I7_BOVIN", "mass": 89404.0, "length": 817, "protein_name": "Protein phosphatase 1 regulatory subunit 9B", "gene_name": "PPP1R9B", "organism": "Bovine", "refseq_name": "neurabin-2", "refseq_ac": "XP_024836587", "gene_names_uniprotkb": "PPP1R9B", "gene_names_refseq": "PPP1R9B", "protein_names_uniprotkb": "Protein phosphatase 1 regulatory subunit 9B", "protein_names_refseq": "neurabin-2", "tax_id": 9913, "disease": "", "pathway": " (bta:101906096)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0051015 actin filament binding;GO:0003779 actin binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0014069 postsynaptic density;GO:0015629 actin cytoskeleton;GO:0030027 lamellipodium", "go_biological_process": "GO:0007015 actin filament organization;GO:0016477 cell migration;GO:0019722 calcium-mediated signaling;GO:0031175 neuron projection development;GO:0046847 filopodium assembly", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1M3I7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1M3R2-1", "uniprot_id": "A0A3Q1M3R2_BOVIN", "mass": 93690.0, "length": 837, "protein_name": "Phosphodiesterase", "gene_name": "PDE8A", "organism": "Bovine", "refseq_name": "high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A isoform X1", "refseq_ac": "XP_010815247", "gene_names_uniprotkb": "PDE8A", "gene_names_refseq": "PDE8A", "protein_names_uniprotkb": "Phosphodiesterase; 3.1.4.-", "protein_names_refseq": "high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A isoform X1", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-418555)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in maintaining basal levels of the cyclic nucleotide and/or in the cAMP regulation of germ cell development. Binding to RAF1 reduces RAF1 'Ser-259' inhibitory-phosphorylation and stimulates RAF1-dependent EGF-activated ERK-signaling. 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(R-BTA-2132295); (R-BTA-2467813); (R-BTA-2500257); (R-BTA-3371497); (R-BTA-5620924); (R-BTA-6807878); (R-BTA-6811436); (R-BTA-9646399); (R-BTA-9648025)", "pathway_count": 10, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. 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CRK-associated substrate; p130cas", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-186763); (R-BTA-372708); (R-BTA-4420097); (R-BTA-8849471)", "pathway_count": 4, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0017124 SH3 domain binding;GO:0019901 protein kinase binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005925 focal adhesion;GO:0030424 axon;GO:0005886 plasma membrane;GO:0015629 actin cytoskeleton", "go_biological_process": "GO:0007155 cell adhesion;GO:0007169 cell surface receptor protein tyrosine kinase signaling pathway;GO:0016477 cell migration;GO:0086100 endothelin receptor signaling pathway;GO:0007015 actin filament organization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1M7M1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1M516-1", "uniprot_id": "A0A3Q1M516_BOVIN", "mass": 86568.0, "length": 777, "protein_name": "Acyl-CoA dehydrogenase family member 11", "gene_name": "ACAD10", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "ACAD10", "gene_names_refseq": "", "protein_names_uniprotkb": "Acyl-CoA dehydrogenase family member 11", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Participates in fatty acid beta-oxidation (FAO) and energy production in the central nervous system (CNS), and to a lesser extent in the liver. Catalyzes the first step in FAO, which consists in the proR-proR stereospecific alpha,beta-dehydrogenation of fatty acyl-CoA thioesters using the electron transfer flavoprotein (ETF) as their physiologic electron acceptor, with maximal activity towards saturated docosanoyl-CoA (CoA 22:0) in both the cerebellum and the liver. Among the different mitochondrial acyl-CoA dehydrogenases, its FAO activity overlaps with that of ACADV and ACADL, but plays a primary role in tissues where it is the main long-chain ACAD expressed, such as the CNS, where together with ACAD9, they accommodate the full spectrum of long chain fatty acid substrates., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.3.8.7;1.3.8.8;1.3.8.9", "go_molecular_function": "GO:0003995 acyl-CoA dehydrogenase activity;GO:0050660 flavin adenine dinucleotide binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005777 peroxisome;GO:0031966 mitochondrial membrane", "go_biological_process": "GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1M516-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MDQ0-1", "uniprot_id": "A0A3Q1MDQ0_BOVIN", "mass": 73483.0, "length": 676, "protein_name": "T-cell differentiation antigen CD6", "gene_name": "CD6", "organism": "Bovine", "refseq_name": "T-cell differentiation antigen CD6 isoform X3", "refseq_ac": "XP_002699304", "gene_names_uniprotkb": "CD6", "gene_names_refseq": "CD6", "protein_names_uniprotkb": "T-cell differentiation antigen CD6", "protein_names_refseq": "T-cell differentiation antigen CD6 isoform X3", "tax_id": 9913, "disease": "", "pathway": " (bta:282881)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Cell adhesion molecule that mediates cell-cell contacts and regulates T-cell responses via its interaction with ALCAM/CD166. Contributes to signaling cascades triggered by activation of the TCR/CD3 complex. Functions as a costimulatory molecule; promotes T-cell activation and proliferation. Contributes to the formation and maturation of the immunological synapse. Functions as a calcium-dependent pattern receptor that binds and aggregates both Gram-positive and Gram-negative bacteria. Binds both lipopolysaccharide (LPS) from Gram-negative bacteria and lipoteichoic acid from Gram-positive bacteria. LPS binding leads to the activation of signaling cascades and down-stream MAP kinases. Mediates activation of the inflammatory response and the secretion of pro-inflammatory cytokines in response to LPS., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0042802 identical protein binding;GO:0001530 lipopolysaccharide binding;GO:0070891 lipoteichoic acid binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0042101 T cell receptor complex;GO:0001772 immunological synapse", "go_biological_process": "GO:0007155 cell adhesion;GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0042102 positive regulation of T cell proliferation;GO:0031663 lipopolysaccharide-mediated signaling pathway;GO:0002438 acute inflammatory response to antigenic stimulus", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MDQ0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MCS9-1", "uniprot_id": "A0A3Q1MCS9_BOVIN", "mass": 85338.0, "length": 776, "protein_name": "Neutral ceramidase", "gene_name": "ASAH2", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "ASAH2", "gene_names_refseq": "", "protein_names_uniprotkb": "Neutral ceramidase; 3.5.1.23", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-9840310)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.5.1.23;3.5.1.-;3.5.1.60", "go_molecular_function": "GO:0046872 metal ion binding;GO:0017040 N-acylsphingosine amidohydrolase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0005615 extracellular space;GO:0005739 mitochondrion;GO:0005901 caveola", "go_biological_process": "GO:0046513 ceramide biosynthetic process;GO:0046512 sphingosine biosynthetic process;GO:0046514 ceramide catabolic process;GO:0044241 lipid digestion;GO:0042759 long-chain fatty acid biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MCS9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1M5V9-1", "uniprot_id": "A0A3Q1M5V9_BOVIN", "mass": 10864.0, "length": 94, "protein_name": "C-C motif chemokine", "gene_name": "CCL26", "organism": "Bovine", "refseq_name": "C-C motif chemokine 26 precursor", "refseq_ac": "NP_001192564", "gene_names_uniprotkb": "CCL26", "gene_names_refseq": "CCL26", "protein_names_uniprotkb": "C-C motif chemokine", "protein_names_refseq": "C-C motif chemokine 26 precursor", "tax_id": 9913, "disease": "", "pathway": " (bta:508387)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0031737 CX3C chemokine receptor binding;GO:0008009 chemokine activity;GO:0048020 CCR chemokine receptor binding;GO:0031728 CCR3 chemokine receptor binding", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0006954 inflammatory response;GO:0030335 positive regulation of cell migration;GO:0061844 antimicrobial humoral immune response mediated by antimicrobial peptide;GO:0070098 chemokine-mediated signaling pathway;GO:0001938 positive regulation of endothelial cell proliferation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1M5V9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1M5Z8-1", "uniprot_id": "A0A3Q1M5Z8_BOVIN", "mass": 37893.0, "length": 358, "protein_name": "Acyl-protein thioesterase 1", "gene_name": "LYPLA1", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "LYPLA1", "gene_names_refseq": "", "protein_names_uniprotkb": "Acyl-protein thioesterase 1; 3.1.2.22; Lysophospholipase 1; Lysophospholipase I; Palmitoyl-protein hydrolase", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-203615); (R-BTA-9648002)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Acts as an acyl-protein thioesterase. Hydrolyzes fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS. Acts as a palmitoyl thioesterase that catalyzes depalmitoylation of proteins, such as ADRB2, KCNMA1 and SQSTM1. Acts as a negative regulator of autophagy by mediating palmitoylation of SQSTM1, decreasing affinity between SQSTM1 and ATG8 proteins and recruitment of ubiquitinated cargo proteins to autophagosomes. Acts as a lysophospholipase and hydrolyzes lysophosphatidylcholine (lyso-PC). Also hydrolyzes lysophosphatidylethanolamine (lyso-PE), lysophosphatidylinositol (lyso-PI) and lysophosphatidylserine (lyso-PS). Has much higher thioesterase activity than lysophospholipase activity. Contributes to the production of lysophosphatidic acid (LPA) during blood coagulation by recognizing and cleaving plasma phospholipids to generate lysophospholipids which in turn act as substrates for ENPP2 to produce LPA., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.6.5.2;3.1.1.4;3.1.1.3;3.1.1.5;3.1.2.22;3.1.2.2;3.1.1.93;3.5.1.1;3.1.1.47;3.4.19.12;1.14.13.39;3.1.1.13;3.1.1.6;2.3.1.-;3.1.2.-;3.1.1.32", "go_molecular_function": "GO:0008474 palmitoyl-(protein) hydrolase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005783 endoplasmic reticulum;GO:0005886 plasma membrane;GO:0031965 nuclear membrane", "go_biological_process": "GO:0006631 fatty acid metabolic process;GO:0042997 negative regulation of Golgi to plasma membrane protein transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1M5Z8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1M6A7-1", "uniprot_id": "A0A3Q1M6A7_BOVIN", "mass": 51699.0, "length": 457, "protein_name": "[histone H4]-N-methyl-L-lysine20 N-methyltransferase KMT5B", "gene_name": "KMT5C", "organism": "Bovine", "refseq_name": "histone-lysine N-methyltransferase KMT5C isoform X2", "refseq_ac": "XP_002695433", "gene_names_uniprotkb": "KMT5C", "gene_names_refseq": "KMT5C", "protein_names_uniprotkb": "[histone H4]-N-methyl-L-lysine20 N-methyltransferase KMT5B; 2.1.1.361; 2.1.1.362; [histone H4]-lysine20 N-methyltransferase KMT5B", "protein_names_refseq": "histone-lysine N-methyltransferase KMT5C isoform X2", "tax_id": 9913, "disease": "", "pathway": " (bta:519777); (R-BTA-3214841)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.1.1.362;2.1.1.361;2.1.1.359;2.1.1.355;2.1.1.354;2.1.1.364", "go_molecular_function": "GO:0003682 chromatin binding;GO:0042393 histone binding;GO:1904047 S-adenosyl-L-methionine binding;GO:0042799 histone H4K20 methyltransferase activity;GO:0140941 histone H4K20me methyltransferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0000779 condensed chromosome, centromeric region;GO:0005721 pericentric heterochromatin", "go_biological_process": "GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining;GO:0006281 DNA repair;GO:0006351 DNA-templated transcription;GO:0032259 methylation;GO:0045830 positive regulation of isotype switching", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1M6A7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MK49-1", "uniprot_id": "A0A3Q1MK49_BOVIN", "mass": 466131.0, "length": 4049, "protein_name": "A-kinase anchoring protein 9", "gene_name": "AKAP9", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "AKAP9", "gene_names_refseq": "", "protein_names_uniprotkb": "A-kinase anchoring protein 9", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0060090 molecular adaptor activity;GO:0003677 DNA binding;GO:0044325 transmembrane transporter binding;GO:0034237 protein kinase A regulatory subunit binding;GO:0099104 potassium channel activator activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005813 centrosome;GO:0098978 glutamatergic synapse;GO:0008076 voltage-gated potassium channel complex;GO:0005795 Golgi stack", "go_biological_process": "GO:0007165 signal transduction;GO:0071320 cellular response to cAMP;GO:0086091 regulation of heart rate by cardiac conduction;GO:0007020 microtubule nucleation;GO:0051661 maintenance of centrosome location", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MK49-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MAC0-1", "uniprot_id": "A0A3Q1MAC0_BOVIN", "mass": 70034.0, "length": 605, "protein_name": "Formin-binding protein 1-like", "gene_name": "FNBP1L", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "FNBP1L", "gene_names_refseq": "", "protein_names_uniprotkb": "Formin-binding protein 1-like; Transducer of Cdc42-dependent actin assembly protein 1", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-8856828)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008289 lipid binding;GO:0051020 GTPase binding", "go_cellular_component": "GO:0005856 cytoskeleton;GO:0005886 plasma membrane;GO:0005938 cell cortex;GO:0031410 cytoplasmic vesicle;GO:0005829 cytosol", "go_biological_process": "GO:0006897 endocytosis;GO:0007165 signal transduction;GO:0006914 autophagy;GO:0010324 membrane invagination;GO:0006900 vesicle budding from membrane", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MAC0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MEV3-1", "uniprot_id": "A0A3Q1MEV3_BOVIN", "mass": 65130.0, "length": 760, "protein_name": "Elastin", "gene_name": "ELN", "organism": "Bovine", "refseq_name": "elastin isoform X1", "refseq_ac": "XP_005225311", "gene_names_uniprotkb": "ELN", "gene_names_refseq": "ELN", "protein_names_uniprotkb": "Elastin; Tropoelastin", "protein_names_refseq": "elastin isoform X1", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-1474228); (R-BTA-1566948); (R-BTA-2129379)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005201 extracellular matrix structural constituent;GO:0050840 extracellular matrix binding;GO:0030023 extracellular matrix constituent conferring elasticity", "go_cellular_component": "GO:0031012 extracellular matrix;GO:0071953 elastic fiber", "go_biological_process": "GO:0085029 extracellular matrix assembly;GO:0003151 outflow tract morphogenesis;GO:0003180 aortic valve morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MEV3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1M7Q2-1", "uniprot_id": "A0A3Q1M7Q2_BOVIN", "mass": 147190.0, "length": 1293, "protein_name": "TRAF2 and NCK interacting kinase", "gene_name": "TNIK", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "TNIK", "gene_names_refseq": "", "protein_names_uniprotkb": "TRAF2 and NCK interacting kinase", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0005856 cytoskeleton;GO:0016324 apical plasma membrane", "go_biological_process": "GO:0035556 intracellular signal transduction;GO:0046330 positive regulation of JNK cascade;GO:0048814 regulation of dendrite morphogenesis;GO:0030036 actin cytoskeleton organization;GO:1903698 positive regulation of microvillus assembly", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1M7Q2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1M8L1-1", "uniprot_id": "A0A3Q1M8L1_BOVIN", "mass": 233628.0, "length": 2044, "protein_name": "Dedicator of cytokinesis 4", "gene_name": "DOCK4", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "DOCK4", "gene_names_refseq": "", "protein_names_uniprotkb": "Dedicator of cytokinesis 4", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-9013404); (R-BTA-9013408); (R-BTA-983231)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Functions as a guanine nucleotide exchange factor (GEF) that promotes the exchange of GDP to GTP, converting inactive GDP-bound small GTPases into their active GTP-bound form. Involved in regulation of adherens junction between cells. Plays a role in cell migration., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Has a higher guanine nucleotide exchange factor activity compared to other isoforms., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0017124 SH3 domain binding;GO:0005085 guanyl-nucleotide exchange factor activity;GO:0031267 small GTPase binding;GO:0030165 PDZ domain binding;GO:0030971 receptor tyrosine kinase binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0032420 stereocilium;GO:0043226 organelle", "go_biological_process": "GO:0007264 small GTPase-mediated signal transduction;GO:0060326 cell chemotaxis;GO:1904754 positive regulation of vascular associated smooth muscle cell migration;GO:1904694 negative regulation of vascular associated smooth muscle contraction", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1M8L1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1M8X0-1", "uniprot_id": "A0A3Q1M8X0_BOVIN", "mass": 23310.0, "length": 224, "protein_name": "Claudin", "gene_name": "CLDN19", "organism": "Bovine", "refseq_name": "claudin-19 isoform X1", "refseq_ac": "XP_005204775", "gene_names_uniprotkb": "CLDN19", "gene_names_refseq": "CLDN19", "protein_names_uniprotkb": "Claudin", "protein_names_refseq": "claudin-19 isoform X1", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Claudins function as major constituents of the tight junction complexes that regulate the permeability of epithelia., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005198 structural molecule activity;GO:0098632 cell-cell adhesion mediator activity;GO:0160187 paracellular tight junction channel activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005886 plasma membrane;GO:0005923 bicellular tight junction;GO:0016323 basolateral plasma membrane;GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "GO:0043297 apical junction assembly;GO:0008285 negative regulation of cell population proliferation;GO:0010628 positive regulation of gene expression;GO:0010629 negative regulation of gene expression;GO:0030336 negative regulation of cell migration", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1M8X0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1M996-1", "uniprot_id": "A0A3Q1M996_BOVIN", "mass": 139761.0, "length": 1262, "protein_name": "Tripeptidyl-peptidase 2", "gene_name": "TPP2", "organism": "Bovine", "refseq_name": "tripeptidyl-peptidase 2 isoform X1", "refseq_ac": "XP_005214009", "gene_names_uniprotkb": "TPP2", "gene_names_refseq": "TPP-2; TPP2", "protein_names_uniprotkb": "Tripeptidyl-peptidase 2; 3.4.14.10; Tripeptidyl aminopeptidase; Tripeptidyl-peptidase II", "protein_names_refseq": "tripeptidyl-peptidase 2 isoform X1", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-983168)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Cytosolic tripeptidyl-peptidase that releases N-terminal tripeptides from polypeptides and is a component of the proteolytic cascade acting downstream of the 26S proteasome in the ubiquitin-proteasome pathway. It plays an important role in intracellular amino acid homeostasis. Stimulates adipogenesis., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.4.14.10;3.4.22.40;3.4.11.-", "go_molecular_function": "GO:0004252 serine-type endopeptidase activity;GO:0008240 tripeptidyl-peptidase activity;GO:0004177 aminopeptidase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0005737 cytoplasm", "go_biological_process": "GO:0006508 proteolysis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1M996-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1M9D9-1", "uniprot_id": "A0A3Q1M9D9_BOVIN", "mass": 92426.0, "length": 839, "protein_name": "Mannosyl-oligosaccharide glucosidase", "gene_name": "MOGS", "organism": "Bovine", "refseq_name": "mannosyl-oligosaccharide glucosidase", "refseq_ac": "XP_024855131", "gene_names_uniprotkb": "MOGS", "gene_names_refseq": "MOGS", "protein_names_uniprotkb": "Mannosyl-oligosaccharide glucosidase; 3.2.1.106; Glucosidase I", "protein_names_refseq": "mannosyl-oligosaccharide glucosidase", "tax_id": 9913, "disease": "", "pathway": " (bta:516155); (R-BTA-9768727)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Cleaves the distal alpha 1,2-linked glucose residue from the Glc(3)Man(9)GlcNAc(2) oligosaccharide precursor., [UniProtKB, UniProtKB, UniProtKB]; In the context of N-glycan degradation, cleaves the distal alpha 1,2-linked glucose residue from the Glc(3)Man(9)GlcNAc(2) oligosaccharide precursor in a highly specific manner., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.2.1.106", "go_molecular_function": "GO:0004573 Glc3Man9GlcNAc2 oligosaccharide glucosidase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006487 protein N-linked glycosylation;GO:0009311 oligosaccharide metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1M9D9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1M9H7-1", "uniprot_id": "A0A3Q1M9H7_BOVIN", "mass": 19857.0, "length": 171, "protein_name": "Interleukin family protein", "gene_name": "IL26", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "IL26", "gene_names_refseq": "", "protein_names_uniprotkb": "Interleukin family protein", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-8854691)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Immune regulatory cytokine., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005125 cytokine activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005829 cytosol", "go_biological_process": "GO:0006955 immune response;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0051897 positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction;GO:0070374 positive regulation of ERK1 and ERK2 cascade;GO:0050680 negative regulation of epithelial cell proliferation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1M9H7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1M9L7-1", "uniprot_id": "A0A3Q1M9L7_BOVIN", "mass": 97053.0, "length": 865, "protein_name": "Mitogen-activated protein kinase kinase kinase kinase", "gene_name": "MAP4K5", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "MAP4K5", "gene_names_refseq": "", "protein_names_uniprotkb": "Mitogen-activated protein kinase kinase kinase kinase; 2.7.11.1", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Serine/threonine kinase that plays a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.11.1;2.7.11.25;2.7.11.24;2.7.11.22;2.7.11.13;2.7.11.23;2.7.12.1;2.7.12.2;2.7.11.17;2.7.11.39;2.7.10.2;2.7.1.150;2.7.11.12;2.7.11.31;2.7.11.26;2.7.11.21;2.7.1.153;2.7.1.137;2.7.1.154;4.1.1.32;2.7.11.38;2.7.11.11;3.1.11.-;2.7.4.6;2.7.13.3;2.7.4.18;3.1.24.-;2.7.11.-;2.7.11.4;2.7.2.3;2.7.11.10", "go_molecular_function": "GO:0005524 ATP binding;GO:0008349 MAP kinase kinase kinase kinase activity;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0035556 intracellular signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1M9L7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MA30-1", "uniprot_id": "A0A3Q1MA30_BOVIN", "mass": 51434.0, "length": 467, "protein_name": "Solute carrier family 2, facilitated glucose transporter member 3", "gene_name": "LOC538810", "organism": "Bovine", "refseq_name": "solute carrier family 2, facilitated glucose transporter member 3-like", "refseq_ac": "XP_059733594", "gene_names_uniprotkb": "LOC538810", "gene_names_refseq": "LOC538810", "protein_names_uniprotkb": "Solute carrier family 2, facilitated glucose transporter member 3; GLUT-3; Glucose transporter type 3", "protein_names_refseq": "solute carrier family 2, facilitated glucose transporter member 3-like", "tax_id": 9913, "disease": "", "pathway": " (bta:538810); (R-BTA-189200)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Facilitative glucose transporter that can also mediate the uptake of various other monosaccharides across the cell membrane. Mediates the uptake of glucose, 2-deoxyglucose, galactose, mannose, xylose and fucose, and probably also dehydroascorbate. Does not mediate fructose transport., [UniProtKB, UniProtKB]; Facilitative glucose transporter. Can also mediate the uptake of various other monosaccharides across the cell membrane. Mediates the uptake of glucose, 2-deoxyglucose, galactose, mannose, xylose and fucose, and probably also dehydroascorbate. Does not mediate fructose transport. Required for mesendoderm differentiation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0033300 dehydroascorbic acid transmembrane transporter activity;GO:0005536 D-glucose binding;GO:0055056 D-glucose transmembrane transporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0043204 perikaryon;GO:0042995 cell projection", "go_biological_process": "GO:0070837 dehydroascorbic acid transport;GO:1904659 D-glucose transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MA30-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MA37-1", "uniprot_id": "A0A3Q1MA37_BOVIN", "mass": 173539.0, "length": 1561, "protein_name": "Serine/threonine-protein kinase MRCK gamma", "gene_name": "CDC42BPG", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "CDC42BPG", "gene_names_refseq": "", "protein_names_uniprotkb": "Serine/threonine-protein kinase MRCK gamma; 2.7.11.1; CDC42-binding protein kinase gamma; DMPK-like gamma; Myotonic dystrophy kinase-related CDC42-binding kinase gamma; Myotonic dystrophy protein kinase-like alpha", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "May act as a downstream effector of CDC42 in cytoskeletal reorganization. Contributes to the actomyosin contractility required for cell invasion, through the regulation of MYPT1 and thus MLC2 phosphorylation., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.11.1;2.7.11.25;2.7.11.24;2.7.11.22;2.7.11.13;2.7.11.23;2.7.12.1;2.7.12.2;2.7.11.17;2.7.11.39;2.7.10.2;2.7.1.150;2.7.11.12;2.7.11.31;2.7.11.26;2.7.11.21;2.7.1.153;2.7.1.137;2.7.1.154;4.1.1.32;2.7.11.38;2.7.11.11;3.1.11.-;2.7.4.6;2.7.13.3;2.7.4.18;3.1.24.-;2.7.11.-;2.7.11.4;2.7.2.3;2.7.11.10", "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005856 cytoskeleton;GO:0031252 cell leading edge", "go_biological_process": "GO:0031032 actomyosin structure organization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MA37-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MA58-1", "uniprot_id": "A0A3Q1MA58_BOVIN", "mass": 119959.0, "length": 1077, "protein_name": "Adenylate cyclase type 4", "gene_name": "ADCY4", "organism": "Bovine", "refseq_name": "adenylate cyclase type 4 isoform X1", "refseq_ac": "XP_024853651", "gene_names_uniprotkb": "ADCY4", "gene_names_refseq": "ADCY4", "protein_names_uniprotkb": "Adenylate cyclase type 4; 4.6.1.1", "protein_names_refseq": "adenylate cyclase type 4 isoform X1", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-163615); (R-BTA-170660); (R-BTA-170670); (R-BTA-418597); (R-BTA-5610787)", "pathway_count": 5, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "4.6.1.1;3.6.5.-;2.7.7.85", "go_molecular_function": "GO:0004016 adenylate cyclase activity;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0005080 protein kinase C binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0030425 dendrite", "go_biological_process": "GO:0006171 cAMP biosynthetic process;GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0035556 intracellular signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MA58-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MA72-1", "uniprot_id": "A0A3Q1MA72_BOVIN", "mass": 58230.0, "length": 563, "protein_name": "Homeobox protein ARX", "gene_name": "ARX", "organism": "Bovine", "refseq_name": "homeobox protein ARX", "refseq_ac": "XP_024844383", "gene_names_uniprotkb": "ARX", "gene_names_refseq": "ARX", "protein_names_uniprotkb": "Homeobox protein ARX; Aristaless-related homeobox", "protein_names_refseq": "homeobox protein ARX", "tax_id": 9913, "disease": "", "pathway": " (bta:529211)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Transcription factor. Binds to specific sequence motif 5'-TAATTA-3' in regulatory elements of target genes, such as histone demethylase KDM5C. Positively modulates transcription of KDM5C. Activates expression of KDM5C synergistically with histone lysine demethylase PHF8 and perhaps in competition with transcription regulator ZNF711; synergy may be related to enrichment of histone H3K4me3 in regulatory elements. Required for normal brain development. Plays a role in neuronal proliferation, interneuronal migration and differentiation in the embryonic forebrain. May also be involved in axonal guidance in the floor plate., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003682 chromatin binding;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0048666 neuron development;GO:0003310 pancreatic A cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MA72-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MAM7-1", "uniprot_id": "A0A3Q1MAM7_BOVIN", "mass": 262139.0, "length": 2341, "protein_name": "Tyrosine-protein kinase receptor", "gene_name": "ROS1", "organism": "Bovine", "refseq_name": "proto-oncogene tyrosine-protein kinase ROS isoform X1", "refseq_ac": "XP_024852728", "gene_names_uniprotkb": "ROS1", "gene_names_refseq": "ROS1", "protein_names_uniprotkb": "Tyrosine-protein kinase receptor; 2.7.10.1", "protein_names_refseq": "proto-oncogene tyrosine-protein kinase ROS isoform X1", "tax_id": 9913, "disease": "", "pathway": " (bta:100336768)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.10.2;2.7.11.23;2.7.12.1;2.7.10.1;2.7.12.2;2.7.11.1;2.7.10.4", "go_molecular_function": "GO:0005524 ATP binding;GO:0019903 protein phosphatase binding;GO:0004714 transmembrane receptor protein tyrosine kinase activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0009986 cell surface;GO:0043235 receptor complex;GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "GO:0007169 cell surface receptor protein tyrosine kinase signaling pathway;GO:0070372 regulation of ERK1 and ERK2 cascade;GO:0032006 regulation of TOR signaling;GO:0002066 columnar/cuboidal epithelial cell development", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MAM7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MAR8-1", "uniprot_id": "A0A3Q1MAR8_BOVIN", "mass": 21374.0, "length": 193, "protein_name": "E2 ubiquitin-conjugating enzyme", "gene_name": "UBE2E1", "organism": "Bovine", "refseq_name": "ubiquitin-conjugating enzyme E2 E1", "refseq_ac": "NP_001193145", "gene_names_uniprotkb": "UBE2E1", "gene_names_refseq": "UBE2E1", "protein_names_uniprotkb": "E2 ubiquitin-conjugating enzyme; 2.3.2.23", "protein_names_refseq": "ubiquitin-conjugating enzyme E2 E1; ubiquitin-conjugating enzyme E2E 1 (UBC4/5 homolog, yeast)", "tax_id": 9913, "disease": "", "pathway": " (bta:615599); (R-BTA-1169408); (R-BTA-141430); (R-BTA-174048); (R-BTA-174084); (R-BTA-174154); (R-BTA-174178); (R-BTA-174184); (R-BTA-176407); (R-BTA-176408); (R-BTA-176409); (R-BTA-176412); (R-BTA-179409); (R-BTA-2467813); (R-BTA-2559582); (R-BTA-68867); (R-BTA-69017); (R-BTA-8866652); (R-BTA-8866654); (R-BTA-983168)", "pathway_count": 20, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.3.2.27;2.3.2.23;2.3.2.31;2.7.11.1;2.3.2.26;3.6.4.13;2.7.10.2;2.3.2.-;6.2.1.45;2.3.2.34;2.3.2.25;2.7.11.24;2.3.2.24;2.7.11.22;2.7.11.23;2.7.11.21;3.4.25.1", "go_molecular_function": "GO:0005524 ATP binding;GO:0042296 ISG15 transferase activity;GO:0061631 ubiquitin conjugating enzyme activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0000151 ubiquitin ligase complex", "go_biological_process": "GO:0070936 protein K48-linked ubiquitination;GO:0032020 ISG15-protein conjugation;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0006513 protein monoubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MAR8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MAW4-1", "uniprot_id": "A0A3Q1MAW4_BOVIN", "mass": 33276.0, "length": 293, "protein_name": "Dehydrodolichyl diphosphate synthase complex subunit NUS1", "gene_name": "NUS1", "organism": "Bovine", "refseq_name": "dehydrodolichyl diphosphate synthase complex subunit NUS1", "refseq_ac": "NP_001242897", "gene_names_uniprotkb": "NUS1", "gene_names_refseq": "NUS1", "protein_names_uniprotkb": "Dehydrodolichyl diphosphate synthase complex subunit NUS1; 2.5.1.87; Dehydrodolichyl diphosphate synthase complex subunit nus1; Nogo-B receptor; Nuclear undecaprenyl pyrophosphate synthase 1 homolog", "protein_names_refseq": "dehydrodolichyl diphosphate syntase complex subunit NUS1 pseudogene; dehydrodolichyl diphosphate synthase complex subunit NUS1; nuclear undecaprenyl pyrophosphate synthase 1 homolog", "tax_id": 9913, "disease": "", "pathway": " (bta:100849670); (R-BTA-446199)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "With DHDDS, forms the dehydrodolichyl diphosphate synthase (DDS) complex, an essential component of the dolichol monophosphate (Dol-P) biosynthetic machinery. Both subunits contribute to enzymatic activity, i.e. condensation of multiple copies of isopentenyl pyrophosphate (IPP) to farnesyl pyrophosphate (FPP) to produce dehydrodolichyl diphosphate (Dedol-PP), a precursor of dolichol phosphate which is utilized as a sugar carrier in protein glycosylation in the endoplasmic reticulum (ER). Synthesizes long-chain polyprenols, mostly of C95 and C100 chain length. Regulates the glycosylation and stability of nascent NPC2, thereby promoting trafficking of LDL-derived cholesterol. Acts as a specific receptor for the N-terminus of Nogo-B, a neural and cardiovascular regulator., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.5.1.87;2.5.1.-", "go_molecular_function": "GO:0045547 ditrans,polycis-polyprenyl diphosphate synthase [(2E,6E)-farnesyl diphosphate specific] activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane;GO:1904423 dehydrodolichyl diphosphate synthase complex", "go_biological_process": "GO:0001525 angiogenesis;GO:0030154 cell differentiation;GO:0032383 regulation of intracellular cholesterol transport;GO:0038084 vascular endothelial growth factor signaling pathway;GO:0043048 dolichyl monophosphate biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MAW4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MB37-1", "uniprot_id": "A0A3Q1MB37_BOVIN", "mass": 88694.0, "length": 792, "protein_name": "Propionate--CoA ligase", "gene_name": "ACSS2", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "ACSS2", "gene_names_refseq": "", "protein_names_uniprotkb": "Propionate--CoA ligase; 6.2.1.17; 6.2.1.1", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "6.2.1.1;6.2.1.17", "go_molecular_function": "GO:0005524 ATP binding;GO:0003987 acetate-CoA ligase activity;GO:0050218 propionate-CoA ligase activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0008610 lipid biosynthetic process;GO:0006629 lipid metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MB37-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MB78-1", "uniprot_id": "A0A3Q1MB78_BOVIN", "mass": 94154.0, "length": 869, "protein_name": "Cadherin-15", "gene_name": "CDH15", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "CDH15", "gene_names_refseq": "", "protein_names_uniprotkb": "Cadherin-15; Cadherin-14; Muscle cadherin", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-418990); (R-BTA-525793)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. M-cadherin is part of the myogenic program and may provide a trigger for terminal muscle differentiation., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005509 calcium ion binding;GO:0045296 cadherin binding;GO:0008013 beta-catenin binding", "go_cellular_component": "GO:0005912 adherens junction;GO:0031594 neuromuscular junction;GO:0005901 caveola;GO:0016342 catenin complex;GO:0005886 plasma membrane", "go_biological_process": "GO:0016477 cell migration;GO:0000902 cell morphogenesis;GO:0007043 cell-cell junction assembly;GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules;GO:0034332 adherens junction organization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MB78-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MBC1-1", "uniprot_id": "A0A3Q1MBC1_BOVIN", "mass": 27302.0, "length": 240, "protein_name": "Tumor protein p53 inducible nuclear protein 1", "gene_name": "TP53INP1", "organism": "Bovine", "refseq_name": "tumor protein p53-inducible nuclear protein 1", "refseq_ac": "NP_001192352", "gene_names_uniprotkb": "TP53INP1", "gene_names_refseq": "TP53INP1", "protein_names_uniprotkb": "Tumor protein p53 inducible nuclear protein 1", "protein_names_refseq": "tumor protein p53-inducible nuclear protein 1", "tax_id": 9913, "disease": "", "pathway": " (bta:782667); (R-BTA-6804756)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0016209 antioxidant activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0031410 cytoplasmic vesicle;GO:0016604 nuclear body;GO:0005776 autophagosome", "go_biological_process": "GO:1904761 negative regulation of myofibroblast differentiation;GO:0000045 autophagosome assembly;GO:0006351 DNA-templated transcription;GO:0010628 positive regulation of gene expression;GO:0010629 negative regulation of gene expression", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MBC1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MBI9-1", "uniprot_id": "A0A3Q1MBI9_BOVIN", "mass": 61672.0, "length": 586, "protein_name": "Thrombomodulin", "gene_name": "", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "", "gene_names_refseq": "", "protein_names_uniprotkb": "Thrombomodulin", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-202733); (R-BTA-9769739)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Endothelial cell receptor that plays a critical role in regulating several physiological processes including hemostasis, coagulation, fibrinolysis, inflammation, and angiogenesis. Acts as a cofactor for thrombin activation of protein C/PROC on the surface of vascular endothelial cells leading to initiation of the activated protein C anticoagulant pathway. Also accelerates the activation of the plasma carboxypeptidase B2/CPB2, which catalyzes removal of C-terminal basic amino acids from its substrates including kinins or anaphylatoxins leading to fibrinolysis inhibition. Plays critical protective roles in changing the cleavage specificity of protease-activated receptor 1/PAR1, inhibiting endothelial cell permeability and inflammation. Suppresses inflammation distinctly from its anticoagulant cofactor activity by sequestering HMGB1 thereby preventing it from engaging cellular receptors such as RAGE and contributing to the inflammatory response., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004888 transmembrane signaling receptor activity;GO:0005509 calcium ion binding", "go_cellular_component": "GO:0009897 external side of plasma membrane", "go_biological_process": "GO:0007596 blood coagulation;GO:0030195 negative regulation of blood coagulation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MBI9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MBK2-1", "uniprot_id": "A0A3Q1MBK2_BOVIN", "mass": 207821.0, "length": 1907, "protein_name": "Plexin-B3", "gene_name": "PLXNB3", "organism": "Bovine", "refseq_name": "plexin-B3 isoform X1", "refseq_ac": "XP_002699769", "gene_names_uniprotkb": "PLXNB3", "gene_names_refseq": "PLXNB3", "protein_names_uniprotkb": "Plexin-B3", "protein_names_refseq": "plexin-B3 isoform X1", "tax_id": 9913, "disease": "", "pathway": " (bta:504294); (R-BTA-416700)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 4, "predicted_n_glycosites": 0, "predicted_o_glycosites": 4, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0019904 protein domain specific binding;GO:0017154 semaphorin receptor activity;GO:0098632 cell-cell adhesion mediator activity;GO:0051022 Rho GDP-dissociation inhibitor binding", "go_cellular_component": "GO:0002116 semaphorin receptor complex;GO:0005886 plasma membrane;GO:0009986 cell surface", "go_biological_process": "GO:0007162 negative regulation of cell adhesion;GO:0010976 positive regulation of neuron projection development;GO:0071526 semaphorin-plexin signaling pathway;GO:0030336 negative regulation of cell migration;GO:0007416 synapse assembly", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MBK2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MBS7-1", "uniprot_id": "A0A3Q1MBS7_BOVIN", "mass": 23563.0, "length": 208, "protein_name": "RAB6A, member RAS onco family", "gene_name": "RAB6A", "organism": "Bovine", "refseq_name": "ras-related protein Rab-6A isoform X1", "refseq_ac": "XP_005216287", "gene_names_uniprotkb": "RAB6A", "gene_names_refseq": "RAB6A", "protein_names_uniprotkb": "RAB6A, member RAS onco family", "protein_names_refseq": "ras-related protein Rab-6A isoform X1", "tax_id": 9913, "disease": "", "pathway": " (bta:616537); (R-BTA-6798695); (R-BTA-6811436); (R-BTA-6811440); (R-BTA-8854214); (R-BTA-8873719); (R-BTA-8876198)", "pathway_count": 7, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0019904 protein domain specific binding;GO:0031489 myosin V binding;GO:0003925 G protein activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005794 Golgi apparatus;GO:0005829 cytosol;GO:0070381 endosome to plasma membrane transport vesicle;GO:0012505 endomembrane system", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0006890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum;GO:0042147 retrograde transport, endosome to Golgi;GO:1903292 protein localization to Golgi membrane;GO:0006891 intra-Golgi vesicle-mediated transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MBS7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MC59-1", "uniprot_id": "A0A3Q1MC59_BOVIN", "mass": 215085.0, "length": 1869, "protein_name": "Dedicator of cytokinesis 5", "gene_name": "DOCK5", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "DOCK5", "gene_names_refseq": "", "protein_names_uniprotkb": "Dedicator of cytokinesis 5", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (bta:505572); (R-BTA-9013408); (R-BTA-983231)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005096 GTPase activator activity;GO:0005085 guanyl-nucleotide exchange factor activity;GO:0031267 small GTPase binding", "go_cellular_component": "GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0002102 podosome;GO:0005737 cytoplasm;GO:0016020 membrane", "go_biological_process": "GO:0016477 cell migration;GO:0016601 Rac protein signal transduction;GO:1900026 positive regulation of substrate adhesion-dependent cell spreading;GO:1904754 positive regulation of vascular associated smooth muscle cell migration;GO:0010634 positive regulation of epithelial cell migration", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MC59-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MC64-1", "uniprot_id": "A0A3Q1MC64_BOVIN", "mass": 48004.0, "length": 430, "protein_name": "PRKCA-binding protein", "gene_name": "PICK1", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "PICK1", "gene_names_refseq": "", "protein_names_uniprotkb": "PRKCA-binding protein; Protein interacting with C kinase 1; Protein kinase C-alpha-binding protein", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-416993)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Probable adapter protein that bind to and organize the subcellular localization of a variety of membrane proteins containing some PDZ recognition sequence. Involved in the clustering of various receptors, possibly by acting at the receptor internalization level. Plays a role in synaptic plasticity by regulating the trafficking and internalization of AMPA receptors. May be regulated upon PRKCA activation. May regulate ASIC1/ASIC3 channel. Regulates actin polymerization by inhibiting the actin-nucleating activity of the Arp2/3 complex; the function is competitive with nucleation promoting factors and is linked to neuronal morphology regulation and AMPA receptor (AMPAR) endocytosis. Via interaction with the Arp2/3 complex involved in regulation of synaptic plasicity of excitatory synapses and required for spine shrinkage during long-term depression (LTD). Involved in regulation of astrocyte morphology, antagonistic to Arp2/3 complex activator WASL/N-WASP function., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003779 actin binding;GO:0019904 protein domain specific binding;GO:0042802 identical protein binding;GO:0046872 metal ion binding;GO:0140090 membrane curvature sensor activity", "go_cellular_component": "GO:0005829 cytosol;GO:0005856 cytoskeleton;GO:0014069 postsynaptic density;GO:0048471 perinuclear region of cytoplasm;GO:0043005 neuron projection", "go_biological_process": "GO:0015844 monoamine transport;GO:0050796 regulation of insulin secretion;GO:0006886 intracellular protein transport;GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation;GO:0002092 positive regulation of receptor internalization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MC64-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MCB1-1", "uniprot_id": "A0A3Q1MCB1_BOVIN", "mass": 54840.0, "length": 505, "protein_name": "Alkaline phosphatase", "gene_name": "", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "", "gene_names_refseq": "", "protein_names_uniprotkb": "Alkaline phosphatase; 3.1.3.1", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-163125)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.5.1.92;3.1.3.1;3.1.3.2;3.1.3.48;2.4.2.31;3.1.3.5;3.1.3.106;3.4.11.9;3.2.2.6;3.1.4.50;3.9.1.1", "go_molecular_function": "GO:0004035 alkaline phosphatase activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0098552 side of membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MCB1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MCH2-1", "uniprot_id": "A0A3Q1MCH2_BOVIN", "mass": 60564.0, "length": 548, "protein_name": "Frizzled class receptor 9", "gene_name": "FZD9", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "FZD9", "gene_names_refseq": "", "protein_names_uniprotkb": "Frizzled class receptor 9", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0042803 protein homodimerization activity;GO:0046982 protein heterodimerization activity;GO:0017147 Wnt-protein binding;GO:0042813 Wnt receptor activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0009986 cell surface;GO:0048471 perinuclear region of cytoplasm;GO:0031527 filopodium membrane", "go_biological_process": "GO:0043524 negative regulation of neuron apoptotic process;GO:0030501 positive regulation of bone mineralization;GO:0060070 canonical Wnt signaling pathway;GO:0090263 positive regulation of canonical Wnt signaling pathway;GO:2000179 positive regulation of neural precursor cell proliferation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MCH2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MCT6-1", "uniprot_id": "A0A3Q1MCT6_BOVIN", "mass": 29991.0, "length": 268, "protein_name": "Proenkephalin-B", "gene_name": "PDYN", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "PDYN", "gene_names_refseq": "", "protein_names_uniprotkb": "Proenkephalin-B; Beta-neoendorphin-dynorphin; Preprodynorphin", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (bta:281385); (R-BTA-111885); (R-BTA-202040); (R-BTA-375276); (R-BTA-418594)", "pathway_count": 5, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Dynorphin peptides differentially regulate the kappa opioid receptor. Dynorphin A(1-13) has a typical opioid activity, it is 700 times more potent than Leu-enkephalin., [UniProtKB, UniProtKB, UniProtKB]; Leu-enkephalins compete with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress., [UniProtKB, UniProtKB, UniProtKB]; Leumorphin has a typical opioid activity and may have anti-apoptotic effect., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, 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"mass": 71230.0, "length": 628, "protein_name": "Shootin-1", "gene_name": "SHTN1", "organism": "Bovine", "refseq_name": "shootin-1 isoform X1", "refseq_ac": "XP_003587946", "gene_names_uniprotkb": "SHTN1", "gene_names_refseq": "SHTN1", "protein_names_uniprotkb": "Shootin-1", "protein_names_refseq": "shootin-1 isoform X1", "tax_id": 9913, "disease": "", "pathway": " (bta:532603)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, 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"reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0042803 protein homodimerization activity;GO:0046982 protein heterodimerization activity;GO:0003730 mRNA 3'-UTR binding;GO:0045182 translation regulator activity;GO:0003729 mRNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0043005 neuron projection;GO:0010494 cytoplasmic stress granule;GO:0098793 presynapse", "go_biological_process": "GO:0043488 regulation of mRNA stability;GO:0045727 positive regulation of translation;GO:0048513 animal organ development;GO:0048170 positive regulation of long-term neuronal synaptic plasticity;GO:0051028 mRNA transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MDB8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1ME66-1", "uniprot_id": "A0A3Q1ME66_BOVIN", "mass": 31662.0, "length": 280, "protein_name": "ADP/ATP translocase", "gene_name": "", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "", "gene_names_refseq": "", "protein_names_uniprotkb": "ADP/ATP translocase; ADP,ATP carrier protein", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalyzes the exchange of ADP and ATP across the membrane., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005471 ATP:ADP antiporter activity", "go_cellular_component": "GO:0005743 mitochondrial inner membrane;GO:0005757 mitochondrial permeability transition pore complex", "go_biological_process": "GO:0046902 regulation of mitochondrial membrane permeability;GO:0140021 mitochondrial ADP transmembrane transport;GO:1990544 mitochondrial ATP transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1ME66-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1ME67-1", "uniprot_id": "A0A3Q1ME67_BOVIN", "mass": 23302.0, "length": 208, "protein_name": "EGF-like domain-containing protein", "gene_name": "", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "", "gene_names_refseq": "", "protein_names_uniprotkb": "EGF-like domain-containing protein", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0038100 nodal binding;GO:0070697 activin receptor binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0009986 cell surface", "go_biological_process": "GO:0007507 heart development;GO:0001568 blood vessel development;GO:0009952 anterior/posterior pattern specification;GO:0038092 nodal signaling pathway;GO:0007368 determination of left/right symmetry", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1ME67-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MEB1-1", "uniprot_id": "A0A3Q1MEB1_BOVIN", "mass": 22413.0, "length": 186, "protein_name": "Uncharacterized protein", "gene_name": "LOC784525", "organism": "Bovine", "refseq_name": "interferon beta-2", "refseq_ac": "XP_002689586", "gene_names_uniprotkb": "LOC784525", "gene_names_refseq": "LOC784525", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "interferon beta-2", "tax_id": 9913, "disease": "", "pathway": " (bta:784525)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005125 cytokine activity;GO:0005132 type I interferon receptor binding", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0002312 B cell activation involved in immune response;GO:0071359 cellular response to dsRNA;GO:0051607 defense response to virus;GO:0060337 type I interferon-mediated signaling pathway;GO:0002250 adaptive immune response", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MEB1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MEL9-1", "uniprot_id": "A0A3Q1MEL9_BOVIN", "mass": 70095.0, "length": 621, "protein_name": "Vacuolar protein sorting-associated protein 33A", "gene_name": "VPS33A", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "VPS33A", "gene_names_refseq": "", "protein_names_uniprotkb": "Vacuolar protein sorting-associated protein 33A", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes which are proposed to be involved in the Rab5-to-Rab7 endosome conversion probably implicating MON1A/B, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion. The HOPS complex is proposed to be recruited to Rab7 on the late endosomal membrane and to regulate late endocytic, phagocytic and autophagic traffic towards lysosomes. The CORVET complex is proposed to function as a Rab5 effector to mediate early endosome fusion probably in specific endosome subpopulations. Required for fusion of endosomes and autophagosomes with lysosomes; the function is dependent on its association with VPS16 but not VIPAS39. The function in autophagosome-lysosome fusion implicates STX17 but not UVRAG., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0060090 molecular adaptor activity", "go_cellular_component": "GO:0030897 HOPS complex;GO:0005769 early endosome;GO:0048471 perinuclear region of cytoplasm;GO:0005765 lysosomal membrane;GO:0031902 late endosome membrane", "go_biological_process": "GO:0097352 autophagosome maturation;GO:0015031 protein transport;GO:0008333 endosome to lysosome transport;GO:0032418 lysosome localization;GO:0032400 melanosome localization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MEL9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MEQ4-1", "uniprot_id": "A0A3Q1MEQ4_BOVIN", "mass": 37671.0, "length": 358, "protein_name": "Krueppel-like factor 2", "gene_name": "KLF2", "organism": "Bovine", "refseq_name": "Krueppel-like factor 2", "refseq_ac": "XP_024850584", "gene_names_uniprotkb": "KLF2", "gene_names_refseq": "KLF2", "protein_names_uniprotkb": "Krueppel-like factor 2; Lung krueppel-like factor", "protein_names_refseq": "Krueppel-like factor 2", "tax_id": 9913, "disease": "", "pathway": " (bta:520939)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Transcription factor that binds to the CACCC box in the promoter of target genes such as HBB/beta globin or NOV and activates their transcription. Might be involved in transcriptional regulation by modulating the binding of the RARA nuclear receptor to RARE DNA elements., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0000785 chromatin", "go_biological_process": "GO:0097533 cellular stress response to acid chemical;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0045944 positive regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MEQ4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MF99-1", "uniprot_id": "A0A3Q1MF99_BOVIN", "mass": 61639.0, "length": 527, "protein_name": "Tyrosine-protein kinase", "gene_name": "TXK", "organism": "Bovine", "refseq_name": "tyrosine-protein kinase TXK isoform X1", "refseq_ac": "XP_024848860", "gene_names_uniprotkb": "TXK", "gene_names_refseq": "TXK", "protein_names_uniprotkb": "Tyrosine-protein kinase; 2.7.10.2", "protein_names_refseq": "tyrosine-protein kinase TXK isoform X1", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-2871809)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.10.2;2.7.11.23;2.7.12.1;2.7.10.1;2.7.12.2;2.7.11.1;3.1.4.11;2.7.10.4", "go_molecular_function": "GO:0004715 non-membrane spanning protein tyrosine kinase activity;GO:0005524 ATP binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005829 cytosol;GO:0005886 plasma membrane", "go_biological_process": "GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0050852 T cell receptor signaling pathway;GO:0002250 adaptive immune response;GO:0032729 positive regulation of type II interferon production;GO:0060335 positive regulation of type II interferon-mediated signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MF99-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MFD0-1", "uniprot_id": "A0A3Q1MFD0_BOVIN", "mass": 96099.0, "length": 865, "protein_name": "Major vault protein", "gene_name": "MVP", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "MVP", "gene_names_refseq": "", "protein_names_uniprotkb": "Major vault protein", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-6798695)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Required for normal vault structure. Vaults are multi-subunit structures that may act as scaffolds for proteins involved in signal transduction. Vaults may also play a role in nucleo-cytoplasmic transport. Down-regulates IFNG-mediated STAT1 signaling and subsequent activation of JAK. Down-regulates SRC activity and signaling through MAP kinases., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0019901 protein kinase binding;GO:0042802 identical protein binding;GO:0019903 protein phosphatase binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0005856 cytoskeleton;GO:0048471 perinuclear region of cytoplasm;GO:1990904 ribonucleoprotein complex", "go_biological_process": "GO:0072376 protein activation cascade;GO:0038127 ERBB signaling pathway;GO:0008283 cell population proliferation;GO:0035556 intracellular signal transduction;GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MFD0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MFN7-1", "uniprot_id": "A0A3Q1MFN7_BOVIN", "mass": 20438.0, "length": 179, "protein_name": "Complexin-2", "gene_name": "CPLX2", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "CPLX2", "gene_names_refseq": "", "protein_names_uniprotkb": "Complexin-2", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0019905 syntaxin binding;GO:0000149 SNARE binding", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0044305 calyx of Held;GO:0005634 nucleus;GO:0005829 cytosol;GO:0043195 terminal bouton", "go_biological_process": "GO:0050804 modulation of chemical synaptic transmission;GO:0031915 positive regulation of synaptic plasticity;GO:0031630 regulation of synaptic vesicle fusion to presynaptic active zone membrane;GO:0016079 synaptic vesicle exocytosis;GO:0006887 exocytosis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MFN7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MFP2-1", "uniprot_id": "A0A3Q1MFP2_BOVIN", "mass": 111475.0, "length": 989, "protein_name": "Rab3 GTPase-activating protein catalytic subunit", "gene_name": "RAB3GAP1", "organism": "Bovine", "refseq_name": "rab3 GTPase-activating protein catalytic subunit isoform X1", "refseq_ac": "XP_059731395", "gene_names_uniprotkb": "RAB3GAP1", "gene_names_refseq": "RAB3GAP1", "protein_names_uniprotkb": "Rab3 GTPase-activating protein catalytic subunit", "protein_names_refseq": "rab3 GTPase-activating protein catalytic subunit isoform X1", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalytic subunit of the Rab3 GTPase-activating (Rab3GAP) complex composed of RAB3GAP1 and RAB3GAP2, which accelerates the otherwise slow GTP hydrolysis catalyzed by Rab proteins. Has GTPase-activating protein (GAP) activity towards various Rab3 subfamily members (RAB3A, RAB3B, RAB3C and RAB3D), RAB5A and RAB43. Additionally, it has guanine nucleotide exchange factor (GEF) activity towards RAB18, promoting GDP release from RAB18 and the conversion of inactive RAB18-GDP to the active form RAB18-GTP. Recruits and stabilizes RAB18 at the cis-Golgi membrane in fibroblasts where RAB18 is most likely activated. Also involved in RAB18 recruitment at the endoplasmic reticulum (ER) membrane where it maintains proper ER structure. Required for normal eye and brain development. May participate in neurodevelopmental processes such as cell proliferation, migration and differentiation before synapse formation, and is involved in regulating non-synaptic vesicular release of neurotransmitters., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005096 GTPase activator activity;GO:0005085 guanyl-nucleotide exchange factor activity;GO:0031267 small GTPase binding", "go_cellular_component": "GO:0005811 lipid droplet;GO:0005801 cis-Golgi network;GO:0032991 protein-containing complex;GO:0071782 endoplasmic reticulum tubular network;GO:0005783 endoplasmic reticulum", "go_biological_process": "GO:0097051 establishment of protein localization to endoplasmic reticulum membrane;GO:0060325 face morphogenesis;GO:0021854 hypothalamus development;GO:1903373 positive regulation of endoplasmic reticulum tubular network organization;GO:0043010 camera-type eye development", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MFP2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MHE7-1", "uniprot_id": "A0A3Q1MHE7_BOVIN", "mass": 171378.0, "length": 1522, "protein_name": "Adhesion G protein-coupled receptor B3", "gene_name": "ADGRB3", "organism": "Bovine", "refseq_name": "adhesion G protein-coupled receptor B3 isoform X1", "refseq_ac": "XP_024852636", "gene_names_uniprotkb": "ADGRB3", "gene_names_refseq": "ADGRB3", "protein_names_uniprotkb": "Adhesion G protein-coupled receptor B3; Brain-specific angiogenesis inhibitor 3", "protein_names_refseq": "adhesion G protein-coupled receptor B3 isoform X1", "tax_id": 9913, "disease": "", "pathway": " (bta:100337167)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Receptor that plays a role in the regulation of synaptogenesis and dendritic spine formation at least partly via interaction with ELMO1 and RAC1 activity. Promotes myoblast fusion through ELMO/DOCK1., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0005096 GTPase activator activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0098794 postsynapse;GO:0043083 synaptic cleft;GO:0098839 postsynaptic density membrane;GO:0150053 cerebellar climbing fiber to Purkinje cell synapse", "go_biological_process": "GO:0007166 cell surface receptor signaling pathway;GO:0007186 G protein-coupled receptor signaling pathway;GO:0016322 neuron remodeling;GO:0048814 regulation of dendrite morphogenesis;GO:0007520 myoblast fusion", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MHE7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MHH5-1", "uniprot_id": "A0A3Q1MHH5_BOVIN", "mass": 121643.0, "length": 1103, "protein_name": "Mitogen-activated protein kinase kinase kinase", "gene_name": "MAP3K9", "organism": "Bovine", "refseq_name": "mitogen-activated protein kinase kinase kinase 9", "refseq_ac": "NP_001193781", "gene_names_uniprotkb": "MAP3K9", "gene_names_refseq": "MAP3K9", "protein_names_uniprotkb": "Mitogen-activated protein kinase kinase kinase; 2.7.11.25", "protein_names_refseq": "mitogen-activated protein kinase kinase kinase 9", "tax_id": 9913, "disease": "", "pathway": " (bta:538340)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.11.1;2.7.11.25;2.7.11.24;2.7.11.22;2.7.11.13;2.7.11.23;2.7.12.1;2.7.12.2;2.7.11.17;2.7.11.39;2.7.10.2;2.7.1.150;2.7.11.12;2.7.11.31;2.7.11.26;2.7.11.21;2.7.1.153;2.7.1.137;2.7.1.154;4.1.1.32;2.7.11.38;2.7.11.11;3.1.11.-;2.7.4.6;2.7.13.3;2.7.4.18;3.1.24.-;2.7.11.-;2.7.11.4;2.7.2.3;2.7.11.10", "go_molecular_function": "GO:0005524 ATP binding;GO:0004706 JUN kinase kinase kinase activity;GO:0106310 protein serine kinase activity;GO:0004709 MAP kinase kinase kinase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0007165 signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MHH5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MHL9-1", "uniprot_id": "A0A3Q1MHL9_BOVIN", "mass": 31179.0, "length": 276, "protein_name": "E3 SUMO-protein ligase NSE2", "gene_name": "NSMCE2", "organism": "Bovine", "refseq_name": "E3 SUMO-protein ligase NSE2 isoform X1", "refseq_ac": "XP_010810259", "gene_names_uniprotkb": "NSMCE2", "gene_names_refseq": "NSMCE2", "protein_names_uniprotkb": "E3 SUMO-protein ligase NSE2; E3 SUMO-protein transferase NSE2; Non-structural maintenance of chromosomes element 2 homolog", "protein_names_refseq": "E3 SUMO-protein ligase NSE2 isoform X1", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-3108214)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0004842 ubiquitin-protein transferase activity;GO:0019789 SUMO transferase activity;GO:0061665 SUMO ligase activity", "go_cellular_component": "GO:0016605 PML body;GO:0000781 chromosome, telomeric region;GO:0030915 Smc5-Smc6 complex;GO:0005634 nucleus", "go_biological_process": "GO:0016925 protein sumoylation;GO:0051301 cell division;GO:0016567 protein ubiquitination;GO:0045842 positive regulation of mitotic metaphase/anaphase transition;GO:0000724 double-strand break repair via homologous recombination", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MHL9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MHS1-1", "uniprot_id": "A0A3Q1MHS1_BOVIN", "mass": 34785.0, "length": 318, "protein_name": "Ribose-phosphate pyrophosphokinase 2", "gene_name": "PRPS2", "organism": "Bovine", "refseq_name": "ribose-phosphate pyrophosphokinase 2 isoform X3", "refseq_ac": "XP_024843920", "gene_names_uniprotkb": "PRPS2", "gene_names_refseq": "PRPS2", "protein_names_uniprotkb": "Ribose-phosphate pyrophosphokinase 2; 2.7.6.1; Phosphoribosyl pyrophosphate synthase II", "protein_names_refseq": "ribose-phosphate pyrophosphokinase 2 isoform X3", "tax_id": 9913, "disease": "", "pathway": " (bta:537688); (R-BTA-73843)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.6.1", "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0005524 ATP binding;GO:0016301 kinase activity;GO:0004749 ribose phosphate diphosphokinase activity;GO:0042802 identical protein binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0009156 ribonucleoside monophosphate biosynthetic process;GO:0006015 5-phosphoribose 1-diphosphate biosynthetic process;GO:0006164 purine nucleotide biosynthetic process;GO:0009165 nucleotide biosynthetic process;GO:0006098 pentose-phosphate shunt", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MHS1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MJN8-1", "uniprot_id": "A0A3Q1MJN8_BOVIN", "mass": 60070.0, "length": 530, "protein_name": "Neuronal acetylcholine receptor subunit beta-2", "gene_name": "CHRNB2", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "CHRNB2", "gene_names_refseq": "", "protein_names_uniprotkb": "Neuronal acetylcholine receptor subunit beta-2", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-629587); 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2.3.2.27", "protein_names_refseq": "seven in absentia homolog 3 isoform X1", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity;GO:0031624 ubiquitin conjugating enzyme binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion", "go_biological_process": "GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0031647 regulation of protein stability;GO:0016567 protein ubiquitination;GO:1903215 negative regulation of protein targeting to mitochondrion", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MK03-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MKD6-1", "uniprot_id": "A0A3Q1MKD6_BOVIN", "mass": 29230.0, "length": 262, "protein_name": "CD40 ligand", "gene_name": "CD40LG", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "CD40LG", "gene_names_refseq": "", "protein_names_uniprotkb": "CD40 ligand; CD40-L; Tumor necrosis factor ligand superfamily member 5", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-198933); (R-BTA-5668541); (R-BTA-5676594)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Acts as a ligand for integrins, specifically ITGA5:ITGB1 and ITGAV:ITGB3; both integrins and the CD40 receptor are required for activation of CD40-CD40LG signaling, which have cell-type dependent effects, such as B-cell activation, NF-kappa-B signaling and anti-apoptotic signaling., [UniProtKB, UniProtKB]; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005125 cytokine activity;GO:0005174 CD40 receptor binding;GO:0005164 tumor necrosis factor receptor binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005886 plasma membrane;GO:0009986 cell surface", "go_biological_process": "GO:0006954 inflammatory response;GO:0006955 immune response;GO:0007166 cell surface receptor signaling pathway;GO:0002682 regulation of immune system process;GO:0030168 platelet activation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MKD6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1ML43-1", "uniprot_id": "A0A3Q1ML43_BOVIN", "mass": 22107.0, "length": 195, "protein_name": "Interferon tau c1", "gene_name": "IFN-tau-c1", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "IFN-tau-c1", "gene_names_refseq": "", "protein_names_uniprotkb": "Interferon tau c1", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005125 cytokine activity;GO:0005132 type I interferon receptor binding", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0002312 B cell activation involved in immune response;GO:0051607 defense response to virus;GO:0060337 type I interferon-mediated signaling pathway;GO:0002250 adaptive immune response;GO:0043330 response to exogenous dsRNA", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1ML43-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MLX1-1", "uniprot_id": "A0A3Q1MLX1_BOVIN", "mass": 78120.0, "length": 720, "protein_name": "Denticleless protein homolog", "gene_name": "DTL", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "DTL", "gene_names_refseq": "", "protein_names_uniprotkb": "Denticleless protein homolog; Lethal(2) denticleless protein homolog; Retinoic acid-regulated nuclear matrix-associated protein", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-110314); (R-BTA-8951664)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004842 ubiquitin-protein transferase activity;GO:0030674 protein-macromolecule adaptor activity", "go_cellular_component": "GO:0031464 Cul4A-RING E3 ubiquitin ligase complex;GO:0005654 nucleoplasm;GO:0005813 centrosome;GO:0031965 nuclear membrane;GO:0005694 chromosome", "go_biological_process": "GO:0010971 positive regulation of G2/M transition of mitotic cell cycle;GO:0009411 response to UV;GO:0048511 rhythmic process;GO:0045732 positive regulation of protein catabolic process;GO:0000209 protein polyubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MLX1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1NAI2-1", "uniprot_id": "A0A3Q1NAI2_BOVIN", "mass": 83016.0, "length": 755, "protein_name": "Thyroid peroxidase", "gene_name": "TPO", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "TPO", "gene_names_refseq": "", "protein_names_uniprotkb": "Thyroid peroxidase; 1.11.1.8", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-209968)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Iodination and coupling of the hormonogenic tyrosines in thyroglobulin to yield the thyroid hormones T(3) and T(4)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.11.1.8;1.6.3.1", "go_molecular_function": "GO:0046872 metal ion binding;GO:0020037 heme binding;GO:0004447 iodide peroxidase activity;GO:0005509 calcium ion binding;GO:0004601 peroxidase activity", "go_cellular_component": "GO:0016020 membrane;GO:0005615 extracellular space", "go_biological_process": "GO:0006979 response to oxidative stress;GO:0042446 hormone biosynthetic process;GO:0042744 hydrogen peroxide catabolic process;GO:0006590 thyroid hormone generation;GO:0006082 organic acid metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1NAI2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q58DH2-1", "uniprot_id": "PISD_BOVIN", "mass": 47244.0, "length": 416, "protein_name": "Phosphatidylserine decarboxylase proenzyme, mitochondrial", "gene_name": "PISD; PRR14L", "organism": "Bovine", "refseq_name": "phosphatidylserine decarboxylase proenzyme, mitochondrial", "refseq_ac": "NP_001019646", "gene_names_uniprotkb": "PISD; PRR14L; PISD", "gene_names_refseq": "PISD", "protein_names_uniprotkb": "Phosphatidylserine decarboxylase proenzyme, mitochondrial; 4.1.1.65", "protein_names_refseq": "phosphatidylserine decarboxylase proenzyme, mitochondrial", "tax_id": 9913, "disease": "", "pathway": " (bta:505332); (bta:787908)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "16305752;6859873", "class_list": "", "function": "Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine. May be involved in lipid droplet biogenesis at the endoplasmic reticulum membrane (By similarity)., [UniProtKB, HAMAP, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "4.1.1.65", "go_molecular_function": "GO:0004609 phosphatidylserine decarboxylase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane;GO:0005811 lipid droplet;GO:0005634 nucleus;GO:0005829 cytosol", "go_biological_process": "GO:0016540 protein autoprocessing;GO:0035694 mitochondrial protein catabolic process;GO:0006646 phosphatidylethanolamine biosynthetic process;GO:0010821 regulation of mitochondrion organization;GO:0140042 lipid droplet formation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q58DH2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q6QRN6-1", "uniprot_id": "NNRE_BOVIN", "mass": 31363.0, "length": 288, "protein_name": "NAD(P)H-hydrate epimerase", "gene_name": "AIBP; NAXE", "organism": "Bovine", "refseq_name": "NAD(P)H-hydrate epimerase precursor", "refseq_ac": "NP_991365", "gene_names_uniprotkb": "AIBP; NAXE; AIBP; APOA1BP; NAXE", "gene_names_refseq": "AIBP; APOA1BP; NAXE", "protein_names_uniprotkb": "NAD(P)H-hydrate epimerase; 5.1.99.6; AI-BP; Apolipoprotein A-I-binding protein; NAD(P)HX epimerase", "protein_names_refseq": "AI-BP; NAD(P)H-hydrate epimerase precursor; NAD(P)H-hydrate epimerase; apolipoprotein A-I-binding protein; apoliprotein A-I binding protein; apoliprotein A-I-interacting protein", "tax_id": 9913, "disease": "", "pathway": " (bta:404132); (R-BTA-196807)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "15278903", "class_list": "", "function": "Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX. Accelerates cholesterol efflux from endothelial cells to high-density lipoprotein (HDL) and thereby regulates angiogenesis (By similarity)., [UniProtKB, HAMAP, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "5.1.99.6", "go_molecular_function": "GO:0046872 metal ion binding;GO:0000166 nucleotide binding;GO:0052856 NAD(P)HX epimerase activity;GO:0042802 identical protein binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0005739 mitochondrion;GO:0005615 extracellular space;GO:0005829 cytosol;GO:0005929 cilium", "go_biological_process": "GO:0006869 lipid transport;GO:0016525 negative regulation of angiogenesis;GO:0002040 sprouting angiogenesis;GO:0010874 regulation of cholesterol efflux;GO:0046496 nicotinamide nucleotide metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q6QRN6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3ZBL1-1", "uniprot_id": "MTND_BOVIN", "mass": 21487.0, "length": 179, "protein_name": "Acireductone dioxygenase", "gene_name": "ADI1", "organism": "Bovine", "refseq_name": "acireductone dioxygenase", "refseq_ac": "NP_001030545", "gene_names_uniprotkb": "ADI1; MTCBP1", "gene_names_refseq": "ADI1; ARD'; Fe-ARD; MTCBP-1; Ni-ARD", "protein_names_uniprotkb": "Acireductone dioxygenase; 1.13.11.53; 1.13.11.54; ARD'; ARD; Acireductone dioxygenase (Fe(2+)-requiring); Acireductone dioxygenase (Ni(2+)-requiring); Fe-ARD; MTCBP-1; Membrane-type 1 matrix metalloproteinase cytoplasmic tail-binding protein 1; Ni-ARD", "protein_names_refseq": "1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; ARD; aci-reductone dioxygenase; acireductone dioxygenase (Fe(2+)-requiring); acireductone dioxygenase (Ni(2+)-requiring); acireductone dioxygenase; fe-ARD; membrane-type 1 matrix metalloproteinase cytoplasmic tail binding protein-1", "tax_id": 9913, "disease": "", "pathway": " (bta:615764); (R-BTA-1237112)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway. Also down-regulates cell migration mediated by MMP14., [UniProtKB, HAMAP, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "F1N597", "ec_number_list": "1.13.11.54;1.13.11.53", "go_molecular_function": "GO:0005506 iron ion binding;GO:0016491 oxidoreductase activity;GO:0016151 nickel cation binding;GO:0010309 acireductone dioxygenase [iron(II)-requiring] activity;GO:0010308 acireductone dioxygenase (Ni2+-requiring) activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005886 plasma membrane", "go_biological_process": "GO:0019509 L-methionine salvage from methylthioadenosine;GO:0006555 methionine metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q3ZBL1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1NMP3-1", "uniprot_id": "A0A3Q1NMP3_BOVIN", "mass": 34849.0, "length": 301, "protein_name": "Uricase", "gene_name": "UOX", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "UOX", "gene_names_refseq": "", "protein_names_uniprotkb": "Uricase; 1.7.3.3; Urate oxidase", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.7.3.3", "go_molecular_function": "GO:0004846 urate oxidase activity", "go_cellular_component": "GO:0005777 peroxisome", "go_biological_process": "GO:0006145 purine nucleobase catabolic process;GO:0019628 urate catabolic process;GO:0006154 adenosine catabolic process;GO:0006157 deoxyadenosine catabolic process;GO:0006196 AMP catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1NMP3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q5KR49-1", "uniprot_id": "TPM1_BOVIN", "mass": 32695.0, "length": 284, "protein_name": "Tropomyosin alpha-1 chain", "gene_name": "TPM1", "organism": "Bovine", "refseq_name": "tropomyosin alpha-1 chain", "refseq_ac": "NP_001013608", "gene_names_uniprotkb": "TPM1", "gene_names_refseq": "TPM1", "protein_names_uniprotkb": "Tropomyosin alpha-1 chain; Alpha-tropomyosin; Tropomyosin-1", "protein_names_refseq": "tropomyosin 1 (alpha); tropomyosin 1 alpha chain; tropomyosin alpha-1 chain", "tax_id": 9913, "disease": "", "pathway": " (bta:281544); (R-BTA-390522); (R-BTA-445355)", "pathway_count": 3, "publication_count": 6, "publication_id_list": "14500764;14742733;16980359;20682264;23077624;25451174", "class_list": "", "function": "Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments., [UniProtKB, UniProtKB]; Deletion of regions 2-3 in tropomyosin alpha resulted in an 60 % decrease in both isometric tension and stiffness of tropomyosin-reconstituted myocardium., [RefSeq, PubMed]; Over-inhibition of the actomyosin interaction by E40K and E54K Tm mutants leads to a decreased force-generating ability at systole, which is the main mechanism underlying the early pathogenesis of DCM., [RefSeq, PubMed]; The first step of hypertrophic cardiomyopathy pathogenesis with E99K is increased calcium sensitivity and decreased calcium cooperativity, which result in larger tension during partial activation to cause a diastolic problem., [RefSeq, PubMed]; The tendency of smooth muscle tropomyosin to form semi-rigid polymers with continuous and undampened rigidity may compensate for the lack of troponin-based structural support in smooth muscles., [RefSeq, PubMed]; Tm affects the conformation of actin so as to increase the area of hydrophobic interaction between actin and myosin molecules, [RefSeq, PubMed]; Tropomyosin is primarily responsible for the change in the kinetic constants of the elementary steps of the cross bridge cycle., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 8, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0042802 identical protein binding;GO:0042803 protein homodimerization activity;GO:0046982 protein heterodimerization activity;GO:0051015 actin filament binding;GO:0097718 disordered domain specific binding", "go_cellular_component": "GO:0005884 actin filament;GO:0015629 actin cytoskeleton;GO:0030017 sarcomere;GO:0030016 myofibril;GO:0097512 cardiac myofibril", "go_biological_process": "GO:0007015 actin filament organization;GO:0060048 cardiac muscle contraction", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q5KR49-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q5BIM5-1", "uniprot_id": "ZFY27_BOVIN", "mass": 44777.0, "length": 404, "protein_name": "Protrudin", "gene_name": "ZFYVE27", "organism": "Bovine", "refseq_name": "protrudin", "refseq_ac": "NP_001017939", "gene_names_uniprotkb": "ZFYVE27", "gene_names_refseq": "ZFYVE27", "protein_names_uniprotkb": "Protrudin; Zinc finger FYVE domain-containing protein 27", "protein_names_refseq": "protrudin; zinc finger FYVE domain-containing protein 27; zinc finger, FYVE domain containing 27", "tax_id": 9913, "disease": "", "pathway": " (bta:514383)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "Molecular tethering protein, which plays a role in the formation of membrane contact sites between the endoplasmic reticulum and late endosomes/lysosomes. Promotes neurite formation by tethering endosomes to the endoplasmic reticulum membrane: interacts with Rab7-positive late endosomes, acting as a bridge to form endoplasmic reticulum membrane-endosome contact sites. Acts in cooperation with vesicle-associated membrane protein-associated protein (VAPA or VAPB), thereby facilitating loading of the endosome membrane with KIF5, which is required for movement of the endosomes along microtubules in the plus-end direction. Also associates with Rab11-positive recycling endosomes, facilitating exocytosis and membrane expansion. Contributes to both the formation and stabilization of the tubular endoplasmic reticulum network. Involved in endoplasmic reticulum morphogenesis by regulating the sheet-to-tubule balance and possibly the density of tubule interconnections., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A4IFC7", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0042802 identical protein binding", "go_cellular_component": "GO:0032584 growth cone membrane;GO:0005783 endoplasmic reticulum;GO:0016020 membrane;GO:0030424 axon;GO:0030425 dendrite", "go_biological_process": "GO:0031175 neuron projection development;GO:0072659 protein localization to plasma membrane;GO:0016192 vesicle-mediated transport;GO:0045773 positive regulation of axon extension;GO:0048011 neurotrophin TRK receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q5BIM5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3T102-1", "uniprot_id": "EIF3E_BOVIN", "mass": 52191.0, "length": 445, "protein_name": "Eukaryotic translation initiation factor 3 subunit E", "gene_name": "EIF3E", "organism": "Bovine", "refseq_name": "eukaryotic translation initiation factor 3 subunit E", "refseq_ac": "NP_001029775", "gene_names_uniprotkb": "EIF3E; EIF3S6; INT6", "gene_names_refseq": "EIF3E; EIF3S6", "protein_names_uniprotkb": "Eukaryotic translation initiation factor 3 subunit E; Eukaryotic translation initiation factor 3 subunit 6; eIF-3 p48; eIF3e", "protein_names_refseq": "eIF-3 p48; eukaryotic translation initiation factor 3 subunit 6; eukaryotic translation initiation factor 3 subunit E; eukaryotic translation initiation factor 3, subunit 6 48kDa", "tax_id": 9913, "disease": "", "pathway": " (bta:534165); (R-BTA-156827); (R-BTA-72649); (R-BTA-72689); (R-BTA-72695); (R-BTA-72702)", "pathway_count": 6, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression. Required for nonsense-mediated mRNA decay (NMD); may act in conjunction with UPF2 to divert mRNAs from translation to the NMD pathway. May interact with MCM7 and EPAS1 and regulate the proteasome-mediated degradation of these proteins., [UniProtKB, HAMAP, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q1JP76", "ec_number_list": "", "go_molecular_function": "GO:0003743 translation initiation factor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0016605 PML body;GO:0016282 eukaryotic 43S preinitiation complex;GO:0033290 eukaryotic 48S preinitiation complex", "go_biological_process": "GO:0006413 translational initiation;GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0001732 formation of cytoplasmic translation initiation complex;GO:0045727 positive regulation of translation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q3T102-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MWX6-1", "uniprot_id": "A0A3Q1MWX6_BOVIN", "mass": 38982.0, "length": 345, "protein_name": "Regulation of nuclear pre-mRNA domain-containing protein", "gene_name": "RPRD1B", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "RPRD1B", "gene_names_refseq": "", "protein_names_uniprotkb": "Regulation of nuclear pre-mRNA domain-containing protein", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0042802 identical protein binding;GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity;GO:0099122 RNA polymerase II C-terminal domain binding", "go_cellular_component": "GO:0097550 transcription preinitiation complex;GO:0005654 nucleoplasm", "go_biological_process": "GO:0001111 RNA polymerase II promoter clearance;GO:0031124 mRNA 3'-end processing;GO:0008284 positive regulation of cell population proliferation;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0010564 regulation of cell cycle process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MWX6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MPX4-1", "uniprot_id": "A0A3Q1MPX4_BOVIN", "mass": 36424.0, "length": 347, "protein_name": "CDC42 effector protein 4", "gene_name": "CDC42EP4", "organism": "Bovine", "refseq_name": "cdc42 effector protein 4", "refseq_ac": "NP_001039936", "gene_names_uniprotkb": "CDC42EP4", "gene_names_refseq": "CDC42EP4", "protein_names_uniprotkb": "CDC42 effector protein 4", "protein_names_refseq": "CDC42 effector protein (Rho GTPase binding) 4; cdc42 effector protein 4", "tax_id": 9913, "disease": "", "pathway": " (bta:540152); (R-BTA-9013404); (R-BTA-9013406)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q1RMQ9", "ec_number_list": "", "go_molecular_function": "GO:0031267 small GTPase binding", "go_cellular_component": "GO:0005912 adherens junction;GO:0015629 actin cytoskeleton;GO:0012505 endomembrane system;GO:0015630 microtubule cytoskeleton;GO:0045335 phagocytic vesicle", "go_biological_process": "GO:0008360 regulation of cell shape;GO:0031274 positive regulation of pseudopodium assembly;GO:0007266 Rho protein signal transduction;GO:0030838 positive regulation of actin filament polymerization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MPX4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1N147-1", "uniprot_id": "A0A3Q1N147_BOVIN", "mass": 24625.0, "length": 221, "protein_name": "small monomeric GTPase", "gene_name": "RAB1A", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "RAB1A", "gene_names_refseq": "", "protein_names_uniprotkb": "small monomeric GTPase; 3.6.5.2", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.6.5.2;3.6.5.5;3.6.5.-;3.6.5.3;2.7.11.1;3.6.1.5;3.6.1.15;3.6.5.4", "go_molecular_function": "GO:0005525 GTP binding;GO:0003925 G protein activity;GO:0003924 GTPase activity", "go_cellular_component": "GO:0016020 membrane;GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0005829 cytosol;GO:0042470 melanosome", "go_biological_process": "GO:0015031 protein transport;GO:0090110 COPII-coated vesicle cargo loading;GO:1903020 positive regulation of glycoprotein metabolic process;GO:0000045 autophagosome assembly;GO:0006897 endocytosis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1N147-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MZ37-1", "uniprot_id": "A0A3Q1MZ37_BOVIN", "mass": 45655.0, "length": 413, "protein_name": "S-adenosylmethionine synthase", "gene_name": "MAT2A", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "MAT2A", "gene_names_refseq": "", "protein_names_uniprotkb": "S-adenosylmethionine synthase; 2.5.1.6", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalyzes the formation of S-adenosylmethionine from methionine and ATP., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.5.1.6", "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0004478 methionine adenosyltransferase activity;GO:0042802 identical protein binding", "go_cellular_component": "GO:0048269 methionine adenosyltransferase complex", "go_biological_process": "GO:0006730 one-carbon metabolic process;GO:0006556 S-adenosylmethionine biosynthetic process;GO:1904263 positive regulation of TORC1 signaling;GO:0051291 protein heterooligomerization;GO:0034214 protein hexamerization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MZ37-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3ZC09-1", "uniprot_id": "ENOB_BOVIN", "mass": 47096.0, "length": 434, "protein_name": "Beta-enolase", "gene_name": "ENO3", "organism": "Bovine", "refseq_name": "beta-enolase", "refseq_ac": "NP_001029874", "gene_names_uniprotkb": "ENO3", "gene_names_refseq": "ENO3", "protein_names_uniprotkb": "Beta-enolase; 2-phospho-D-glycerate hydro-lyase; 4.2.1.11; Enolase 3; MSE; Muscle-specific enolase; Skeletal muscle enolase", "protein_names_refseq": "2-phospho-D-glycerate hydro-lyase; MSE; beta-enolase; enolase 3 (beta, muscle); muscle-specific enolase; skeletal muscle enolase", "tax_id": 9913, "disease": "", "pathway": " (bta:540303); (R-BTA-70171); (R-BTA-70263)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "30172809", "class_list": "", "function": "Biochemical characterization, homology modelling and investigation of muscle specific enolase, [RefSeq, PubMed]; Enolase that catalyzes the conversion of 2-phosphoglycerate to phosphoenolpyruvate in glycolysis and the reverse reaction in gluconeogenesis. Appears to have a function in striated muscle development and regeneration., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 8, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "4.2.1.11", "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0004634 phosphopyruvate hydratase activity", "go_cellular_component": "GO:0000015 phosphopyruvate hydratase complex;GO:0005886 plasma membrane", "go_biological_process": "GO:0006096 glycolytic process;GO:0061621 canonical glycolysis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q3ZC09-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MMQ9-1", "uniprot_id": "A0A3Q1MMQ9_BOVIN", "mass": 18802.0, "length": 167, "protein_name": "Activated RNA polymerase II transcriptional coactivator p15", "gene_name": "SUB1", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "SUB1", "gene_names_refseq": "", "protein_names_uniprotkb": "Activated RNA polymerase II transcriptional coactivator p15; SUB1 homolog", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "General coactivator that functions cooperatively with TAFs and mediates functional interactions between upstream activators and the general transcriptional machinery. May be involved in stabilizing the multiprotein transcription complex. Binds single-stranded DNA. Also binds, in vitro, non-specifically to double-stranded DNA (ds DNA)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0003713 transcription coactivator activity;GO:0042802 identical protein binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0003697 single-stranded DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005667 transcription regulator complex", "go_biological_process": "GO:0060261 positive regulation of transcription initiation by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0051053 negative regulation of DNA metabolic process;GO:0001111 RNA polymerase II promoter clearance", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MMQ9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q58DQ5-1", "uniprot_id": "RT09_BOVIN", "mass": 45231.0, "length": 396, "protein_name": "Small ribosomal subunit protein uS9m", "gene_name": "MRPS9", "organism": "Bovine", "refseq_name": "small ribosomal subunit protein uS9m", "refseq_ac": "NP_001030409", "gene_names_uniprotkb": "MRPS9", "gene_names_refseq": "MRPS9", "protein_names_uniprotkb": "Small ribosomal subunit protein uS9m; 28S ribosomal protein S9, mitochondrial; MRP-S9; S9mt", "protein_names_refseq": "28S ribosomal protein S9, mitochondrial; MRP-S9; S9mt; small ribosomal subunit protein uS9m", "tax_id": 9913, "disease": "", "pathway": " (bta:519302); (R-BTA-5389840); (R-BTA-5419276); (R-BTA-9937383)", "pathway_count": 4, "publication_count": 3, "publication_id_list": "11344316;16305752;24799711", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "P82676;Q0V8L9;Q32LH0;Q5BIN8", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding;GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005763 mitochondrial small ribosomal subunit;GO:0005743 mitochondrial inner membrane;GO:0005840 ribosome;GO:1990904 ribonucleoprotein complex;GO:0070013 intracellular organelle lumen", "go_biological_process": "GO:0006412 translation", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q58DQ5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q7M3E1-1", "uniprot_id": "CTRC_BOVIN", "mass": 29255.0, "length": 268, "protein_name": "Chymotrypsin-C", "gene_name": "CTRC", "organism": "Bovine", "refseq_name": "chymotrypsin-C precursor", "refseq_ac": "NP_001092435", "gene_names_uniprotkb": "CTRC", "gene_names_refseq": "CTRC; bPTLP", "protein_names_uniprotkb": "Chymotrypsin-C; 3.4.21.2; bPTLP", "protein_names_refseq": "chymotrypsin C (caldecrin); chymotrypsin-C precursor", "tax_id": 9913, "disease": "", "pathway": " (bta:514047)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "11282978;7556081;8907182;9223647", "class_list": "", "function": "Regulates activation and degradation of trypsinogens and procarboxypeptidases by targeting specific cleavage sites within their zymogen precursors (By similarity). Has chymotrypsin-type protease activity and hypocalcemic activity (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A5PJB3", "ec_number_list": "", "go_molecular_function": "GO:0004252 serine-type endopeptidase activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005576 extracellular region", "go_biological_process": "GO:0006508 proteolysis", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q7M3E1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q58DD2-1", "uniprot_id": "S2611_BOVIN", "mass": 65350.0, "length": 602, "protein_name": "Sodium-independent sulfate anion transporter", "gene_name": "SLC26A11", "organism": "Bovine", "refseq_name": "sodium-independent sulfate anion transporter", "refseq_ac": "NP_001014866", "gene_names_uniprotkb": "SLC26A11", "gene_names_refseq": "SLC26A11", "protein_names_uniprotkb": "Sodium-independent sulfate anion transporter; Solute carrier family 26 member 11", "protein_names_refseq": "sodium-independent sulfate anion transporter", "tax_id": 9913, "disease": "", "pathway": " (bta:507491); (R-BTA-174362); (R-BTA-427601)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "Sodium-independent anion exchanger mediating bicarbonate, chloride, sulfate and oxalate transport (By similarity). Exhibits sodium-independent sulfate anion transporter activity that may cooperate with SLC26A2 to mediate DIDS-sensitive sulfate uptake into high endothelial venules endothelial cells (HEVEC) (By similarity). In the kidney, mediates chloride-bicarbonate exchange, facilitating V-ATPase-mediated acid secretion (By similarity). May function as a chloride channel, playing an important role in moderating chloride homeostasis and neuronal activity in the cerebellum (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Sodium-independent anion exchanger mediating bicarbonate, chloride, sulfate and oxalate transport. Exhibits sodium-independent sulfate anion transporter activity that may cooperate with SLC26A2 to mediate DIDS-sensitive sulfate uptake into high endothelial venules endothelial cells (HEVEC). In the kidney, mediates chloride-bicarbonate exchange, facilitating V-ATPase-mediated acid secretion. May function as a chloride channel, playing an important role in moderating chloride homeostasis and neuronal activity in the cerebellum., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A6QPG7", "ec_number_list": "", "go_molecular_function": "GO:0008509 monoatomic anion transmembrane transporter activity;GO:0005254 chloride channel activity;GO:0008271 secondary active sulfate transmembrane transporter activity;GO:0015116 sulfate transmembrane transporter activity;GO:0140900 chloride:bicarbonate antiporter activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0005886 plasma membrane;GO:0016020 membrane;GO:0016323 basolateral plasma membrane", "go_biological_process": "GO:0019532 oxalate transport;GO:1902476 chloride transmembrane transport;GO:1902358 sulfate transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q58DD2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3T0X8-1", "uniprot_id": "NHRF3_BOVIN", "mass": 57175.0, "length": 520, "protein_name": "Na(+)/H(+) exchange regulatory cofactor NHE-RF3", "gene_name": "PDZK1", "organism": "Bovine", "refseq_name": "Na(+)/H(+) exchange regulatory cofactor NHE-RF3", "refseq_ac": "NP_001029783", "gene_names_uniprotkb": "PDZK1; NHERF3; PDZD1", "gene_names_refseq": "NHERF-3; PDZK1", "protein_names_uniprotkb": "Na(+)/H(+) exchange regulatory cofactor NHE-RF3; NHERF-3; Na(+)/H(+) exchanger regulatory factor 3; PDZ domain-containing protein 1; Sodium-hydrogen exchanger regulatory factor 3", "protein_names_refseq": "Na(+)/H(+) exchange regulatory cofactor NHE-RF3; Na(+)/H(+) exchanger regulatory factor 3; PDZ domain-containing protein 1; sodium-hydrogen exchanger regulatory factor 3", "tax_id": 9913, "disease": "", "pathway": " (bta:534439)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "A scaffold protein that connects plasma membrane proteins and regulatory components, regulating their surface expression in epithelial cells apical domains. May be involved in the coordination of a diverse range of regulatory processes for ion transport and second messenger cascades. In complex with NHERF1, may cluster proteins that are functionally dependent in a mutual fashion and modulate the trafficking and the activity of the associated membrane proteins. May play a role in the cellular mechanisms associated with multidrug resistance through its interaction with ABCC2 and PDZK1IP1. May potentiate the CFTR chloride channel activity. Required for normal cell-surface expression of SCARB1. Plays a role in maintaining normal plasma cholesterol levels via its effects on SCARB1. Plays a role in the normal localization and function of the chloride-anion exchanger SLC26A6 to the plasma membrane in the brush border of the proximal tubule of the kidney. May be involved in the regulation of proximal tubular Na(+)-dependent inorganic phosphate cotransport therefore playing an important role in tubule function (By similarity)., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 13, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005102 signaling receptor binding;GO:0043495 protein-membrane adaptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016324 apical plasma membrane;GO:0031526 brush border membrane", "go_biological_process": "GO:0072659 protein localization to plasma membrane;GO:0090314 positive regulation of protein targeting to membrane;GO:0044070 regulation of monoatomic anion transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q3T0X8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3ZBV9-1", "uniprot_id": "DHR11_BOVIN", "mass": 27811.0, "length": 255, "protein_name": "Dehydrogenase/reductase SDR family member 11", "gene_name": "DHRS11", "organism": "Bovine", "refseq_name": "dehydrogenase/reductase SDR family member 11 precursor", "refseq_ac": "NP_001030260", "gene_names_uniprotkb": "DHRS11; SDR24C1", "gene_names_refseq": "DHRS11", "protein_names_uniprotkb": "Dehydrogenase/reductase SDR family member 11; 1.1.1.270; 1.1.1.62; 17-beta-hydroxysteroid dehydrogenase; 3-beta-hydroxysteroid 3-dehydrogenase; Estradiol 17-beta-dehydrogenase; Short-chain dehydrogenase/reductase family 24C member 1", "protein_names_refseq": "17-beta-hydroxysteroid dehydrogenase; 3-beta-hydroxysteroid 3-dehydrogenase; dehydrogenase/reductase SDR family member 11 precursor; dehydrogenase/reductase SDR family member 11; estradiol 17-beta-dehydrogenase; short-chain dehydrogenase/reductase family 24C member 1", "tax_id": 9913, "disease": "", "pathway": " (bta:510264)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalyzes the conversion of the 17-keto group of estrone, 4- and 5-androstenes and 5-alpha-androstanes into their 17-beta-hydroxyl metabolites and the conversion of the 3-keto group of 3-, 3,17- and 3,20- diketosteroids into their 3beta-hydroxyl metabolites. Exhibits reductive 3-beta-hydroxysteroid dehydrogenase activity toward 5-beta-androstanes, 5-beta-pregnanes, 4-pregnenes and bile acids. May contribute to the metabolism of adrenal-derived androgen precursors. Reduces 11-keto-4-androstene-3,17-dione (11KA4) and 11-keto-5alpha-androstane-3,17-dione (11K-Adione) into potent androgens 11-ketotestosterone (11KT) and 11-ketodihydrotestosterone (11KDHT), respectively. May also reduce endogenous and exogenous alpha-dicarbonyl compounds and xenobiotic alicyclic ketones., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.1.1.330;1.1.1.62;1.1.1.-;1.1.1.357;1.1.1.188;1.1.1.239;1.1.1.64;1.1.1.210;1.1.1.53;1.1.1.225;1.1.1.209;1.1.1.51;1.1.1.105;1.1.1.270", "go_molecular_function": "GO:0072582 17-beta-hydroxysteroid dehydrogenase (NADP+) activity;GO:0000166 nucleotide binding;GO:0004303 estradiol 17-beta-dehydrogenase [NAD(P)+] activity;GO:0000253 3-beta-hydroxysteroid 3-dehydrogenase (NADP+) activity", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "GO:0006703 estrogen biosynthetic process;GO:0006694 steroid biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q3ZBV9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q5EA20-1", "uniprot_id": "HPPD_BOVIN", "mass": 44963.0, "length": 393, "protein_name": "4-hydroxyphenylpyruvate dioxygenase", "gene_name": "HPD", "organism": "Bovine", "refseq_name": "4-hydroxyphenylpyruvate dioxygenase", "refseq_ac": "NP_001015611", "gene_names_uniprotkb": "HPD", "gene_names_refseq": "HPD", "protein_names_uniprotkb": "4-hydroxyphenylpyruvate dioxygenase; 1.13.11.27; 2.1.1.348; 4-hydroxyphenylpyruvic acid oxidase; 4HPPD; HPD; HPPDase; N(6)-adenosine-methyltransferase HPD", "protein_names_refseq": "4-hydroxyphenylpyruvate dioxygenase; 4-hydroxyphenylpyruvic acid oxidase; 4HPPD; HPPDase", "tax_id": 9913, "disease": "", "pathway": " (bta:516058); (R-BTA-8963684)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "Catalyzes the conversion of 4-hydroxyphenylpyruvic acid to homogentisic acid, one of the steps in tyrosine catabolism., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.1.1.348;1.13.11.27", "go_molecular_function": "GO:0003868 4-hydroxyphenylpyruvate dioxygenase activity;GO:0042803 protein homodimerization activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006559 L-phenylalanine catabolic process;GO:0006572 L-tyrosine catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q5EA20-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1N6J8-1", "uniprot_id": "A0A3Q1N6J8_BOVIN", "mass": 91910.0, "length": 803, "protein_name": "Oligophrenin-1", "gene_name": "OPHN1", "organism": "Bovine", "refseq_name": "oligophrenin-1 isoform X1", "refseq_ac": "XP_024844559", "gene_names_uniprotkb": "OPHN1", "gene_names_refseq": "OPHN1", "protein_names_uniprotkb": "Oligophrenin-1", "protein_names_refseq": "oligophrenin-1 isoform X1", "tax_id": 9913, "disease": "", "pathway": " (bta:525644); (R-BTA-8980692); (R-BTA-9013106); (R-BTA-9013148); (R-BTA-9013404); (R-BTA-9013406); (R-BTA-9013408); (R-BTA-9013409); (R-BTA-9013423)", "pathway_count": 9, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005096 GTPase activator activity;GO:0003779 actin binding;GO:0005543 phospholipid binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0043197 dendritic spine;GO:0098793 presynapse;GO:0098978 glutamatergic synapse;GO:0015629 actin cytoskeleton", "go_biological_process": "GO:0006897 endocytosis;GO:0007165 signal transduction;GO:0007399 nervous system development;GO:0030100 regulation of endocytosis;GO:0031175 neuron projection development", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1N6J8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3ZC84-1", "uniprot_id": "CNDP2_BOVIN", "mass": 52655.0, "length": 475, "protein_name": "Cytosolic non-specific dipeptidase", "gene_name": "CNDP2", "organism": "Bovine", "refseq_name": "cytosolic non-specific dipeptidase", "refseq_ac": "NP_001030280", "gene_names_uniprotkb": "CNDP2", "gene_names_refseq": "CNDP2", "protein_names_uniprotkb": "Cytosolic non-specific dipeptidase; 3.4.-.-; 3.4.13.18; CNDP dipeptidase 2; N-lactoyl-amino acid synthase/hydrolase; Threonyl dipeptidase", "protein_names_refseq": "CNDP dipeptidase 2; cytosolic non-specific dipeptidase; threonyl dipeptidase", "tax_id": 9913, "disease": "", "pathway": " (bta:512626); (R-BTA-174403); (R-BTA-9753281)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalyzes the peptide bond hydrolysis in dipeptides, displaying a non-redundant activity toward threonyl dipeptides. Mediates threonyl dipeptide catabolism in a tissue-specific way. Has high dipeptidase activity toward cysteinylglycine, an intermediate metabolite in glutathione metabolism. Metabolizes N-lactoyl-amino acids, both through hydrolysis to form lactic acid and amino acids, as well as through their formation by reverse proteolysis. Plays a role in the regulation of cell cycle arrest and apoptosis., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Cytosolic metallodipeptidase with broad substrate specificity that catalyzes the hydrolysis of amide bonds in dipeptides and pseudopeptides. Substrates include L-cysteinylglycine, an intermediate metabolite of the gamma-glutamyl cycle of glutathione metabolism (By similarity). Can also hydrolyze threonyl-containing dipeptides (By similarity). Upon physiological conditions of amino acids and lactate excess can also catalyze a reverse proteolysis reaction, generating N-[(S)-lactoyl]-L-phenylalanine and possibly other N-lactoyl-amino acids which it can also hydrolyze in vitro. N-[(S)-lactoyl]-L-phenylalanine is an exercise-induced metabolite that influences food intake and systemic energy balance. Carnosine is probably not a physiological substrate and L-homocarnosine is not a substrate for this enzyme. Plays a role in the regulation of cell cycle arrest and apoptosis (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.4.11.1;3.4.11.5;3.4.13.23;3.4.13.18;3.4.-.-", "go_molecular_function": "GO:0046872 metal ion binding;GO:0004180 carboxypeptidase activity;GO:0070573 metallodipeptidase activity;GO:0016805 dipeptidase activity;GO:0008237 metallopeptidase activity", "go_cellular_component": "GO:0005829 cytosol;GO:0005737 cytoplasm;GO:0005654 nucleoplasm", "go_biological_process": "GO:0006508 proteolysis;GO:0019184 nonribosomal peptide biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q3ZC84-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3T0N3-1", "uniprot_id": "TMCO1_BOVIN", "mass": 21175.0, "length": 188, "protein_name": "Calcium load-activated calcium channel", "gene_name": "TMCO1", "organism": "Bovine", "refseq_name": "calcium load-activated calcium channel", "refseq_ac": "NP_001029938", "gene_names_uniprotkb": "TMCO1", "gene_names_refseq": "TMCO1", "protein_names_uniprotkb": "Calcium load-activated calcium channel; CLAC channel; GEL complex subunit TMCO1; Transmembrane and coiled-coil domain-containing protein 1", "protein_names_refseq": "CLAC channel; GEL complex subunit TMCO1; calcium load-activated calcium channel; transmembrane and coiled-coil domain-containing protein 1", "tax_id": 9913, "disease": "", "pathway": " (bta:614715)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Endoplasmic reticulum (ER) calcium-selective channel preventing intracellular Ca2(+) stores from overfilling and maintaining calcium homeostasis in the ER. In response to endoplasmic reticulum (ER) Ca2(+) overloading, assembles into a homotetramer, forming a functional calcium-selective channel facilitating Ca2(+) release (By similarity). Mediates ER Ca2(+) homeostasis in osteoblasts and plays a key role in bone formation, via the CaMKII-HDAC4-RUNX2 signaling axis (By similarity). Component of the multi-pass translocon (MPT) complex that mediates insertion of multi-pass membrane proteins into the lipid bilayer of membranes (By similarity). The MPT complex takes over after the SEC61 complex: following membrane insertion of the first few transmembrane segments of proteins by the SEC61 complex, the MPT complex occludes the lateral gate of the SEC61 complex to promote insertion of subsequent transmembrane regions (By similarity). Within the MPT complex, the GEL subcomplex may mediate insertion of transmembrane regions into the membrane (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.11.1", "go_molecular_function": "GO:0005262 calcium channel activity;GO:0043022 ribosome binding", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005737 cytoplasm;GO:0005783 endoplasmic reticulum;GO:0031966 mitochondrial membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0001503 ossification;GO:0070588 calcium ion transmembrane transport;GO:0006983 ER overload response;GO:0032469 endoplasmic reticulum calcium ion homeostasis;GO:0160063 multi-pass transmembrane protein insertion into ER membrane", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q3T0N3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3ZCE8-1", "uniprot_id": "RBM8A_BOVIN", "mass": 19889.0, "length": 174, "protein_name": "RNA-binding protein 8A", "gene_name": "LIX1L; RBM8A", "organism": "Bovine", "refseq_name": "RNA-binding protein 8A", "refseq_ac": "NP_001030401", "gene_names_uniprotkb": "LIX1L; RBM8A; LIX1L", "gene_names_refseq": "RBM8A", "protein_names_uniprotkb": "RNA-binding protein 8A; RNA-binding motif protein 8A", "protein_names_refseq": "RNA-binding protein 8A", "tax_id": 9913, "disease": "", "pathway": " (bta:518045)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs., [UniProtKB, UniProtKB]; Required for pre-mRNA splicing as component of the spliceosome (By similarity). Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. The EJC marks the position of the exon-exon junction in the mature mRNA for the gene expression machinery and the core components remain bound to spliced mRNAs throughout all stages of mRNA metabolism thereby influencing downstream processes including nuclear mRNA export, subcellular mRNA localization, translation efficiency and nonsense-mediated mRNA decay (NMD). Its removal from cytoplasmic mRNAs requires translation initiation from EJC-bearing spliced mRNAs. Associates preferentially with mRNAs produced by splicing. Does not interact with pre-mRNAs, introns, or mRNAs produced from intronless cDNAs. Associates with both nuclear mRNAs and newly exported cytoplasmic mRNAs (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q1JPH7", "ec_number_list": "", "go_molecular_function": "GO:0003729 mRNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0016607 nuclear speck;GO:0071006 U2-type catalytic step 1 spliceosome;GO:0035145 exon-exon junction complex", "go_biological_process": "GO:0006417 regulation of translation;GO:0008380 RNA splicing;GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0000398 mRNA splicing, via spliceosome;GO:0051028 mRNA transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q3ZCE8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q5EA95-1", "uniprot_id": "IFT57_BOVIN", "mass": 48960.0, "length": 429, "protein_name": "Intraflagellar transport protein 57 homolog", "gene_name": "IFT57", "organism": "Bovine", "refseq_name": "intraflagellar transport protein 57 homolog", "refseq_ac": "NP_001098873", "gene_names_uniprotkb": "IFT57", "gene_names_refseq": "ESRRBL1; IFT57", "protein_names_uniprotkb": "Intraflagellar transport protein 57 homolog", "protein_names_refseq": "estrogen-related receptor beta like 1; intraflagellar transport 57 homolog; intraflagellar transport protein 57 homolog", "tax_id": 9913, "disease": "", "pathway": " (bta:531436); (R-BTA-5610787); (R-BTA-5620924)", "pathway_count": 3, "publication_count": 2, "publication_id_list": "11916979;16305752", "class_list": "", "function": "Required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway (By similarity). Together with RAB23 and KIF17, it is required for the localization of specific G protein-coupled receptors, such as dopamime receptor DRD1, to primary cilia. Has pro-apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5'-AAAGACATG-3' present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator; however the relevance of such function remains unclear (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0005929 cilium;GO:0005815 microtubule organizing center;GO:0036064 ciliary basal body;GO:0032391 photoreceptor connecting cilium", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006915 apoptotic process;GO:0042981 regulation of apoptotic process;GO:1905515 non-motile cilium assembly;GO:0042073 intraciliary transport", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q5EA95-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q5BIP9-1", "uniprot_id": "DUS18_BOVIN", "mass": 21028.0, "length": 188, "protein_name": "Dual specificity protein phosphatase 18", "gene_name": "DUSP18", "organism": "Bovine", "refseq_name": "dual specificity protein phosphatase 18", "refseq_ac": "NP_001029431", "gene_names_uniprotkb": "DUSP18", "gene_names_refseq": "DUSP18", "protein_names_uniprotkb": "Dual specificity protein phosphatase 18; 3.1.3.16; 3.1.3.48", "protein_names_refseq": "dual specificity protein phosphatase 18", "tax_id": 9913, "disease": "", "pathway": " (bta:505912)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "Can dephosphorylate single and diphosphorylated synthetic MAPK peptides, with preference for the phosphotyrosine and diphosphorylated forms over phosphothreonine. In vitro, dephosphorylates p-nitrophenyl phosphate (pNPP). In bone tissue, upon activation of the G(q)-dependent KISS1/KISS1R signaling pathway, DUSP18 is recruited to the KISS1R C-terminus, where it dephosphorylates SRC resulting in down-regulation of osteoclast differentiation and activity, and consequently suppression of bone resorption., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q32KN1", "ec_number_list": "3.1.3.48;3.1.3.16;3.1.3.2;3.1.3.67;3.1.3.21;3.1.3.5;3.1.3.74;3.1.3.52;3.1.3.18;3.1.3.53", "go_molecular_function": "GO:0004722 protein serine/threonine phosphatase activity;GO:0008138 protein tyrosine/serine/threonine phosphatase activity;GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity;GO:0016791 phosphatase activity;GO:0004725 protein tyrosine phosphatase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005743 mitochondrial inner membrane;GO:0005654 nucleoplasm", "go_biological_process": "GO:0016311 dephosphorylation;GO:0035335 peptidyl-tyrosine dephosphorylation;GO:0045779 negative regulation of bone resorption;GO:0035970 peptidyl-threonine dephosphorylation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q5BIP9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q5E956-1", "uniprot_id": "TPIS_BOVIN", "mass": 26690.0, "length": 249, "protein_name": "Triosephosphate isomerase", "gene_name": "TPI1", "organism": "Bovine", "refseq_name": "triosephosphate isomerase", "refseq_ac": "NP_001013607", "gene_names_uniprotkb": "TPI1", "gene_names_refseq": "TPI1", "protein_names_uniprotkb": "Triosephosphate isomerase; 4.2.3.3; 5.3.1.1; Methylglyoxal synthase; TIM; Triose-phosphate isomerase", "protein_names_refseq": "TIM; methylglyoxal synthase; triose-phosphate isomerase; triosephosphate isomerase", "tax_id": 9913, "disease": "", "pathway": " (bta:281543); (R-BTA-70171); (R-BTA-70263)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "It is also responsible for the non-negligible production of methylglyoxal a reactive cytotoxic side-product that modifies and can alter proteins, DNA and lipids., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Triosephosphate isomerase is an extremely efficient metabolic enzyme that catalyzes the interconversion between dihydroxyacetone phosphate (DHAP) and D-glyceraldehyde-3-phosphate (G3P) in glycolysis and gluconeogenesis., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 8, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "5.3.1.1;4.2.3.3", "go_molecular_function": "GO:0004807 triose-phosphate isomerase activity;GO:0042803 protein homodimerization activity;GO:0008929 methylglyoxal synthase activity;GO:0031625 ubiquitin protein ligase binding", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0019563 glycerol catabolic process;GO:0006094 gluconeogenesis;GO:0006096 glycolytic process;GO:0019242 methylglyoxal biosynthetic process;GO:0046166 glyceraldehyde-3-phosphate biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q5E956-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q5EA40-1", "uniprot_id": "BCAT2_BOVIN", "mass": 44648.0, "length": 393, "protein_name": "Branched-chain-amino-acid aminotransferase, mitochondrial", "gene_name": "BCAT2", "organism": "Bovine", "refseq_name": "branched-chain-amino-acid aminotransferase, mitochondrial precursor", "refseq_ac": "NP_001013611", "gene_names_uniprotkb": "BCAT2", "gene_names_refseq": "BCAT2", "protein_names_uniprotkb": "Branched-chain-amino-acid aminotransferase, mitochondrial; 2.6.1.42; BCAT(m)", "protein_names_refseq": "BCAT(m); branched chain aminotransferase 2, mitochondrial; branched-chain-amino-acid aminotransferase, mitochondrial precursor; branched-chain-amino-acid aminotransferase, mitochondrial", "tax_id": 9913, "disease": "", "pathway": " (bta:281643); (R-BTA-70895)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine. Branched chain amino acid catabolism plays a role in adipocyte differentiation by providing lipogenic acetyl-CoA pools in differentiated adipocytes. Mechanistically, acetyl-CoA derived from branched chain amino acid catabolism is used by EP300/p300 to acetylate and inhibit PRDM16, thereby preventing adipose tissue browning. May also function as a transporter of branched chain alpha-keto acids., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q0V8P3", "ec_number_list": "2.6.1.42", "go_molecular_function": "GO:0004084 branched-chain-amino-acid transaminase activity;GO:0052654 L-leucine-2-oxoglutarate transaminase activity;GO:0052655 L-valine-2-oxoglutarate transaminase activity;GO:0052656 L-isoleucine-2-oxoglutarate transaminase activity", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0006629 lipid metabolic process;GO:0050873 brown fat cell differentiation;GO:0009098 L-leucine biosynthetic process;GO:0009099 L-valine biosynthetic process;GO:0008652 amino acid biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q5EA40-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MWG1-1", "uniprot_id": "A0A3Q1MWG1_BOVIN", "mass": 67221.0, "length": 626, "protein_name": "Histone-arginine methyltransferase CARM1", "gene_name": "CARM1", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "CARM1", "gene_names_refseq": "", "protein_names_uniprotkb": "Histone-arginine methyltransferase CARM1; 2.1.1.319; Coactivator-associated arginine methyltransferase 1; Protein arginine N-methyltransferase 4", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-3214858); (R-BTA-400206); (R-BTA-9018519); (R-BTA-9707564)", "pathway_count": 4, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.6.4.13;2.3.1.48;2.1.1.319;3.5.1.98", "go_molecular_function": "GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity;GO:0003713 transcription coactivator activity;GO:0070611 histone H3R2 methyltransferase activity;GO:0035642 histone H3R17 methyltransferase activity;GO:0140297 DNA-binding transcription factor binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005694 chromosome;GO:0043596 nuclear replication fork;GO:0005654 nucleoplasm", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006325 chromatin organization;GO:0032259 methylation;GO:0006338 chromatin remodeling;GO:0006355 regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MWG1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q58CQ5-1", "uniprot_id": "ANKZ1_BOVIN", "mass": 81185.0, "length": 728, "protein_name": "tRNA endonuclease ANKZF1", "gene_name": "ANKZF1", "organism": "Bovine", "refseq_name": "tRNA endonuclease ANKZF1", "refseq_ac": "NP_001019668", "gene_names_uniprotkb": "ANKZF1", "gene_names_refseq": "ANKZF1", "protein_names_uniprotkb": "tRNA endonuclease ANKZF1; 3.1.-.-; Ankyrin repeat and zinc finger domain-containing protein 1", "protein_names_refseq": "ankyrin repeat and zinc finger domain containing 1; ankyrin repeat and zinc finger domain-containing protein 1; tRNA endonuclease ANKZF1", "tax_id": 9913, "disease": "", "pathway": " (bta:507867)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "Endonuclease that cleaves polypeptidyl-tRNAs downstream of the ribosome-associated quality control (RQC) pathway to release incompletely synthesized polypeptides for degradation. The RQC pathway disassembles aberrantly stalled translation complexes to recycle or degrade the constituent parts. ANKZF1 acts downstream disassembly of stalled ribosomes and specifically cleaves off the terminal 3'-CCA nucleotides universal to all tRNAs from polypeptidyl-tRNAs, releasing (1) ubiquitinated polypeptides from 60S ribosomal subunit for degradation and (2) cleaved tRNAs. ANKZF1-cleaved tRNAs are then repaired and recycled by ELAC1 and TRNT1. Also plays a role in the cellular response to hydrogen peroxide and in the maintenance of mitochondrial integrity under conditions of cellular stress., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0016787 hydrolase activity;GO:0004521 RNA endonuclease activity;GO:0140101 catalytic activity, acting on a tRNA;GO:0004519 endonuclease activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0072344 rescue of stalled ribosome;GO:0070301 cellular response to hydrogen peroxide;GO:0036503 ERAD pathway;GO:0006515 protein quality control for misfolded or incompletely synthesized proteins", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q58CQ5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3ZBV2-1", "uniprot_id": "DD19A_BOVIN", "mass": 53986.0, "length": 478, "protein_name": "ATP-dependent RNA helicase DDX19A", "gene_name": "DDX19A", "organism": "Bovine", "refseq_name": "ATP-dependent RNA helicase DDX19A", "refseq_ac": "NP_001029743", "gene_names_uniprotkb": "DDX19A", "gene_names_refseq": "DDX19A", "protein_names_uniprotkb": "ATP-dependent RNA helicase DDX19A; 3.6.4.13; DEAD box protein 19A", "protein_names_refseq": "ATP-dependent RNA helicase DDX19A; DEAD (Asp-Glu-Ala-As) box polypeptide 19A; DEAD (Asp-Glu-Ala-Asp) box polypeptide 19A; DEAD box protein 19A", "tax_id": 9913, "disease": "", "pathway": " (bta:529929)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "ATP-dependent RNA helicase involved in mRNA export from the nucleus. Rather than unwinding RNA duplexes, DDX19 functions as a remodeler of ribonucleoprotein particles, whereby proteins bound to nuclear mRNA are dissociated and replaced by cytoplasmic mRNA binding proteins., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.6.4.12;5.6.2.4;3.6.4.13;2.3.2.27;7.2.2.-;2.7.7.7;2.7.7.49;3.6.1.5;3.6.4.6;3.6.4.10;5.6.2.3;3.6.5.-;5.6.2.-;2.7.4.3;3.6.4.-;2.7.11.1;3.1.-.-;4.2.99.18;5.6.1.6;3.6.1.15;7.6.2.1;3.1.3.1;3.9.1.1;5.6.2.5;3.4.24.-;3.6.-.-;3.6.1.-;5.6.1.7;3.1.4.-;3.4.21.53", "go_molecular_function": "GO:0003729 mRNA binding;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0003724 RNA helicase activity;GO:0003723 RNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0010494 cytoplasmic stress granule;GO:0005737 cytoplasm", "go_biological_process": "GO:0016973 poly(A)+ mRNA export from nucleus", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q3ZBV2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3T127-1", "uniprot_id": "U2AF4_BOVIN", "mass": 25884.0, "length": 220, "protein_name": "Splicing factor U2AF 26 kDa subunit", "gene_name": "U2AF1L4", "organism": "Bovine", "refseq_name": "splicing factor U2AF 26 kDa subunit", "refseq_ac": "NP_001029950", "gene_names_uniprotkb": "U2AF1L4", "gene_names_refseq": "TMEM149; U2AF1L4", "protein_names_uniprotkb": "Splicing factor U2AF 26 kDa subunit; U2 small nuclear RNA auxiliary factor 1-like protein 4; U2AF1-like 4", "protein_names_refseq": "U2 small nuclear RNA auxiliary factor 1-like protein 4; U2AF1-like 4; splicing factor U2AF 26 kDa subunit; transmembrane protein 149", "tax_id": 9913, "disease": "", "pathway": " (bta:615198); (R-BTA-159236); (R-BTA-72163); (R-BTA-9770562)", "pathway_count": 4, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "RNA-binding protein that function as a pre-mRNA splicing factor. Plays a critical role in both constitutive and enhancer-dependent splicing by mediating protein-protein interactions and protein-RNA interactions required for accurate 3'-splice site selection. Acts by enhancing the binding of U2AF2 to weak pyrimidine tracts. Also participates in the regulation of alternative pre-mRNA splicing. Activates exon 5 skipping of PTPRC during T-cell activation; an event reversed by GFI1. Binds to RNA at the AG dinucleotide at the 3'-splice site (By similarity). Shows a preference for AGC or AGA (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0030628 pre-mRNA 3'-splice site binding;GO:0003723 RNA binding;GO:0003677 DNA binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0016607 nuclear speck;GO:0005681 spliceosomal complex;GO:0089701 U2AF complex", "go_biological_process": "GO:0000398 mRNA splicing, via spliceosome", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q3T127-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q5E9P1-1", "uniprot_id": "ABRX1_BOVIN", "mass": 46184.0, "length": 410, "protein_name": "BRCA1-A complex subunit Abraxas 1", "gene_name": "ABRAXAS1", "organism": "Bovine", "refseq_name": "BRCA1-A complex subunit Abraxas 1", "refseq_ac": "NP_001015516", "gene_names_uniprotkb": "ABRAXAS1; ABRA1; CCDC98; FAM175A", "gene_names_refseq": "ABRAXAS1; CCDC98; FAM175A", "protein_names_uniprotkb": "BRCA1-A complex subunit Abraxas 1; Coiled-coil domain-containing protein 98; Protein FAM175A", "protein_names_refseq": "BRCA1-A complex subunit Abraxas 1; coiled-coil domain containing 98; coiled-coil domain-containing protein 98; family with sequence similarity 175 member A", "tax_id": 9913, "disease": "", "pathway": " (bta:504796); (R-BTA-5689901); (R-BTA-5693565); (R-BTA-5693571); (R-BTA-5693607); (R-BTA-69473)", "pathway_count": 6, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "Involved in DNA damage response and double-strand break (DSB) repair. Component of the BRCA1-A complex, acting as a central scaffold protein that assembles the various components of the complex and mediates the recruitment of BRCA1. The BRCA1-A complex specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesion sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at DSBs. This complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A4FV82", "ec_number_list": "", "go_molecular_function": "GO:0008017 microtubule binding;GO:0031593 polyubiquitin modification-dependent protein binding", "go_cellular_component": "GO:0005634 nucleus;GO:0070531 BRCA1-A complex;GO:0016604 nuclear body;GO:0000922 spindle pole;GO:0005874 microtubule", "go_biological_process": "GO:0008608 attachment of spindle microtubules to kinetochore;GO:0090307 mitotic spindle assembly;GO:0006302 double-strand break repair;GO:0010212 response to ionizing radiation;GO:0045739 positive regulation of DNA repair", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q5E9P1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3T147-1", "uniprot_id": "DX39B_BOVIN", "mass": 48964.0, "length": 428, "protein_name": "Spliceosome RNA helicase DDX39B", "gene_name": "DDX39B", "organism": "Bovine", "refseq_name": "spliceosome RNA helicase DDX39B", "refseq_ac": "NP_001028801", "gene_names_uniprotkb": "DDX39B; BAT1; UAP56", "gene_names_refseq": "BAT1; DDX39B", "protein_names_uniprotkb": "Spliceosome RNA helicase DDX39B; 3.6.4.13; 56 kDa U2AF65-associated protein; DEAD box protein UAP56", "protein_names_refseq": "56 kDa U2AF65-associated protein; DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B; DEAD box protein UAP56; DEAD-box helicase 39B; DEADD box protein; HLA-B associated transcript 1; spliceosome RNA helicase BAT1; spliceosome RNA helicase DDX39B", "tax_id": 9913, "disease": "", "pathway": " (bta:540191); (R-BTA-159236); (R-BTA-72163); (R-BTA-9013418)", "pathway_count": 4, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Involved in nuclear export of spliced and unspliced mRNA. Component of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and specifically associates with spliced mRNA and not with unspliced pre-mRNA. The TREX complex is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NXF1 pathway. The THOC1-THOC2-THOC3 core complex alone is sufficient to promote ATPase activity of DDX39B; in the complex THOC2 is the only component that directly interacts with DDX39B. Associates with SARNP/CIP29, which facilitates RNA binding of DDX39B and likely plays a role in mRNA export. May undergo several rounds of ATP hydrolysis during assembly of TREX to drive subsequent loading of components such as ALYREF/THOC4 and CHTOP onto mRNA. Also associates with pre-mRNA independent of ALYREF/THOC4. Involved in the nuclear export of intronless mRNA; the ATP-bound form is proposed to recruit export adapter ALYREF/THOC4 to intronless mRNA; its ATPase activity is cooperatively stimulated by RNA and ALYREF/THOC4 and ATP hydrolysis is thought to trigger the dissociation from RNA to allow the association of ALYREF/THOC4 and the NXF1-NXT1 heterodimer. Involved in transcription elongation and genome stability., [UniProtKB, UniProtKB]; Splice factor that is required for the first ATP-dependent step in spliceosome assembly and for the interaction of U2 snRNP with the branchpoint. Has both RNA-stimulated ATP binding/hydrolysis activity and ATP-dependent RNA unwinding activity. Even with the stimulation of RNA, the ATPase activity is weak. Can only hydrolyze ATP but not other NTPs. The RNA stimulation of ATPase activity does not have a strong preference for the sequence and length of the RNA. However, ssRNA stimulates the ATPase activity much more strongly than dsRNA. Can unwind 5' or 3' overhangs or blunt end RNA duplexes in vitro. The ATPase and helicase activities are not influenced by U2AF2; the effect of ALYREF/THOC4 is reported conflictingly., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.6.4.12;5.6.2.4;3.6.4.13;2.3.2.27;7.2.2.-;2.7.7.7;2.7.7.49;3.6.1.5;3.6.4.6;5.2.1.8;3.6.4.10;5.6.2.3;3.6.5.-;2.7.11.1;5.6.2.-;2.7.4.3;3.6.4.-;3.1.13.-;2.7.7.48;2.7.7.6;3.1.-.-;4.2.99.18;5.6.1.6;3.6.1.15;7.6.2.1;3.1.3.1;3.9.1.1;5.6.2.5;3.4.24.-;3.6.-.-;3.6.1.-;5.6.1.7;3.1.4.-;3.4.21.53", "go_molecular_function": "GO:0030621 U4 snRNA binding;GO:0003729 mRNA binding;GO:0005524 ATP binding;GO:0042802 identical protein binding;GO:0016887 ATP hydrolysis activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0016607 nuclear speck;GO:0005681 spliceosomal complex;GO:0000346 transcription export complex;GO:0005687 U4 snRNP", "go_biological_process": "GO:0006406 mRNA export from nucleus;GO:0000398 mRNA splicing, via spliceosome;GO:0000245 spliceosomal complex assembly", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q3T147-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3ZBC0-1", "uniprot_id": "RPAB4_BOVIN", "mass": 7004.0, "length": 58, "protein_name": "DNA-directed RNA polymerases I, II, and III subunit RPABC4", "gene_name": "POLR2K", "organism": "Bovine", "refseq_name": "DNA-directed RNA polymerases I, II, and III subunit RPABC4", "refseq_ac": "NP_001032712", "gene_names_uniprotkb": "POLR2K", "gene_names_refseq": "POLR2K", "protein_names_uniprotkb": "DNA-directed RNA polymerases I, II, and III subunit RPABC4; DNA-directed RNA polymerase II subunit K; RNA polymerases I, II, and III subunit ABC4", "protein_names_refseq": "DNA-directed RNA polymerase II subunit K; DNA-directed RNA polymerases I, II, and III subunit RPABC4; RNA polymerases I, II, and III subunit ABC4; polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa", "tax_id": 9913, "disease": "", "pathway": " (bta:614776); (R-BTA-112382); (R-BTA-113418); (R-BTA-5250924); (R-BTA-5578749); (R-BTA-674695); (R-BTA-6781823); (R-BTA-6782135); (R-BTA-6782210); (R-BTA-6796648); (R-BTA-6803529); (R-BTA-6807505); (R-BTA-72086); (R-BTA-72163); (R-BTA-72165); (R-BTA-72203); (R-BTA-73762); (R-BTA-73772); (R-BTA-73776); (R-BTA-73779); (R-BTA-73863); (R-BTA-75953); (R-BTA-75955); (R-BTA-76042); (R-BTA-76061); (R-BTA-76066); (R-BTA-76071); (R-BTA-77075); (R-BTA-9018519); (R-BTA-9770562)", "pathway_count": 30, "publication_count": 3, "publication_id_list": "16769904;26789250;28892040", "class_list": "", "function": "DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and a small RNAs, such as 5S rRNA and tRNAs, respectively., [UniProtKB, UniProtKB, UniProtKB, PubMed, UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0003899 DNA-directed RNA polymerase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0001650 fibrillar center;GO:0005665 RNA polymerase II, core complex;GO:0005736 RNA polymerase I complex;GO:0005666 RNA polymerase III complex", "go_biological_process": "GO:0006366 transcription by RNA polymerase II;GO:0006367 transcription initiation at RNA polymerase II promoter;GO:0006368 transcription elongation by RNA polymerase II;GO:0006362 transcription elongation by RNA polymerase I;GO:0006386 termination of RNA polymerase III transcription", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q3ZBC0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MRJ4-1", "uniprot_id": "A0A3Q1MRJ4_BOVIN", "mass": 62187.0, "length": 568, "protein_name": "Solute carrier family 11 member 2", "gene_name": "SLC11A2", "organism": "Bovine", "refseq_name": "natural resistance-associated macrophage protein 2 isoform X2", "refseq_ac": "XP_024847549", "gene_names_uniprotkb": "SLC11A2", "gene_names_refseq": "SLC11A2", "protein_names_uniprotkb": "Solute carrier family 11 member 2", "protein_names_refseq": "natural resistance-associated macrophage protein 2 isoform X2", "tax_id": 9913, "disease": "", "pathway": " (bta:521189); (R-BTA-425410); (R-BTA-917937)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0046873 metal ion transmembrane transporter activity;GO:0046870 cadmium ion binding;GO:0005384 manganese ion transmembrane transporter activity;GO:0015087 cobalt ion transmembrane transporter activity;GO:0015093 ferrous iron transmembrane transporter activity", "go_cellular_component": "GO:0005765 lysosomal membrane;GO:0031902 late endosome membrane;GO:0005886 plasma membrane;GO:0010008 endosome membrane", "go_biological_process": "GO:0006826 iron ion transport;GO:0034755 iron ion transmembrane transport;GO:0006879 intracellular iron ion homeostasis;GO:0006828 manganese ion transport;GO:0030026 intracellular manganese ion homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MRJ4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q5E9N5-1", "uniprot_id": "CLPB_BOVIN", "mass": 75440.0, "length": 677, "protein_name": "Mitochondrial disaggregase", "gene_name": "CLPB", "organism": "Bovine", "refseq_name": "mitochondrial disaggregase", "refseq_ac": "NP_001015625", "gene_names_uniprotkb": "CLPB; SKD3", "gene_names_refseq": "CLPB; SKD3", "protein_names_uniprotkb": "Mitochondrial disaggregase; 3.6.1.-; Suppressor of potassium transport defect 3", "protein_names_refseq": "ClpB caseinolytic peptidase B homolog; ClpB homolog, mitochondrial AAA ATPase chaperonin; caseinolytic peptidase B protein homolog; mitochondrial disaggregase; suppressor of potassium transport defect 3", "tax_id": 9913, "disease": "", "pathway": " (bta:520639)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "Functions as a regulatory ATPase and participates in secretion/protein trafficking process. Has ATP-dependent protein disaggregase activity and is required to maintain the solubility of key mitochondrial proteins. Involved in mitochondrial-mediated antiviral innate immunity, activates RIG-I-mediated signal transduction and production of IFNB1 and pro-inflammatory cytokine IL6. Plays a role in granulocyte differentiation., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.6.4.12;5.6.2.4;3.6.4.13;2.3.2.27;7.2.2.-;2.7.7.7;2.7.7.49;3.6.1.5;3.6.4.6;3.6.4.10;5.6.2.3;3.6.5.-;5.6.2.-;2.7.4.3;3.6.4.-;2.7.11.1;3.1.-.-;4.2.99.18;5.6.1.6;3.6.1.15;7.6.2.1;3.1.3.1;3.9.1.1;5.6.2.5;3.4.24.-;3.6.-.-;3.6.1.-;5.6.1.7;3.1.4.-;3.4.21.53", "go_molecular_function": "GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0140545 ATP-dependent protein disaggregase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005758 mitochondrial intermembrane space", "go_biological_process": "GO:0034605 cellular response to heat;GO:0030851 granulocyte differentiation;GO:0039529 RIG-I signaling pathway;GO:0140374 antiviral innate immune response", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q5E9N5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q4PKH3-1", "uniprot_id": "CLCN7_BOVIN", "mass": 88831.0, "length": 809, "protein_name": "H(+)/Cl(-) exchange transporter 7", "gene_name": "CLCN7", "organism": "Bovine", "refseq_name": "H(+)/Cl(-) exchange transporter 7", "refseq_ac": "NP_001020502", "gene_names_uniprotkb": "CLCN7", "gene_names_refseq": "CLC-7; CLC7; CLCN7", "protein_names_uniprotkb": "H(+)/Cl(-) exchange transporter 7; Chloride channel 7 alpha subunit; Chloride channel protein 7; ClC-7", "protein_names_refseq": "H(+)/Cl(-) exchange transporter 7; chloride channel 7 alpha subunit; chloride channel protein 7", "tax_id": 9913, "disease": "", "pathway": " (bta:513545); (R-BTA-2672351)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "24159188", "class_list": "", "function": "Accelerated ClC-7/Ostm1 gating per se is deleterious, highlighting a physiological importance of the slow voltage-activation of ClC-7/Ostm1 in lysosomal function and bone resorption, [RefSeq, PubMed]; Slowly voltage-gated channel mediating the exchange of chloride ions against protons (By similarity). Functions as antiporter and contributes to the acidification of the lysosome lumen and may be involved in maintaining lysosomal pH (By similarity). The CLC channel family contains both chloride channels and proton-coupled anion transporters that exchange chloride or another anion for protons (By similarity). The presence of conserved gating glutamate residues is typical for family members that function as antiporters (By similarity)., [UniProtKB, UniProtKB, UniProtKB]; Slowly voltage-gated channel mediating the exchange of chloride ions against protons. Functions as antiporter and contributes to the acidification of the lysosome lumen and may be involved in maintaining lysosomal pH. The CLC channel family contains both chloride channels and proton-coupled anion transporters that exchange chloride or another anion for protons. The presence of conserved gating glutamate residues is typical for family members that function as antiporters., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0062158 chloride:proton antiporter activity;GO:0005254 chloride channel activity", "go_cellular_component": "GO:0005765 lysosomal membrane;GO:0034707 chloride channel complex;GO:0016020 membrane", "go_biological_process": "GO:1902476 chloride transmembrane transport;GO:0030321 transepithelial chloride transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q4PKH3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q599T9-1", "uniprot_id": "MYD88_BOVIN", "mass": 33709.0, "length": 296, "protein_name": "Myeloid differentiation primary response protein MyD88", "gene_name": "MYD88", "organism": "Bovine", "refseq_name": "myeloid differentiation primary response protein MyD88", "refseq_ac": "NP_001014404", "gene_names_uniprotkb": "MYD88", "gene_names_refseq": "MYD88", "protein_names_uniprotkb": "Myeloid differentiation primary response protein MyD88", "protein_names_refseq": "myeloid differentiation factor 88; myeloid differentiation primary response 88; myeloid differentiation primary response gene (88); myeloid differentiation primary response protein MyD88", "tax_id": 9913, "disease": "", "pathway": " (bta:444881); (R-BTA-1257604); (R-BTA-1810476); (R-BTA-209543); (R-BTA-3134963); (R-BTA-6811558); (R-BTA-9020702)", "pathway_count": 7, "publication_count": 6, "publication_id_list": "16701904;17936907;18760477;23545302;26043978;27236308", "class_list": "", "function": "Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, PubMed, UniProtKB, PubMed]; L. rhamnosus GR-1 ameliorates the E. coli-induced disruption of cellular ultrastructure, subsequently reducing the percentage of bovine endometrial epithelial cells apoptosis and limiting inflammatory responses, partly via attenuation of MyD88-dependent and MyD88-independent pathway activation, [RefSeq, PubMed]; Modulated cytokine expression in Bovine viral diarrhea virus type 2 infected macrophages was associated with decreased MyD88 expression., [RefSeq, PubMed]; MyD88 plays a functional role in transducing LPS signaling from TLR-4 to downstream effector molecules involved in NF-kappaB activation, [RefSeq, PubMed]; The study demonstrates that in cattle, animals heterozygous at the MyD88 A625C polymorphic marker have a 5-fold reduced risk for active pulmonary tuberculosis., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q49BZ6;Q49CF6;Q6GV22", "ec_number_list": "", "go_molecular_function": "GO:0035325 Toll-like receptor binding;GO:0070976 TIR domain binding;GO:0005126 cytokine receptor binding;GO:0042802 identical protein binding;GO:0035591 signaling adaptor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0005829 cytosol;GO:0009986 cell surface", "go_biological_process": "GO:0006954 inflammatory response;GO:0045087 innate immune response;GO:0050830 defense response to Gram-positive bacterium;GO:0051607 defense response to virus;GO:0043123 positive regulation of canonical NF-kappaB signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q599T9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MZY8-1", "uniprot_id": "A0A3Q1MZY8_BOVIN", "mass": 72262.0, "length": 664, "protein_name": "Sphingomyelin phosphodiesterase 3", "gene_name": "SMPD3", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "SMPD3", "gene_names_refseq": "", "protein_names_uniprotkb": "Sphingomyelin phosphodiesterase 3; 3.1.4.12; Neutral sphingomyelinase 2; Neutral sphingomyelinase II", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (bta:514201); (R-BTA-5626978); (R-BTA-9840310)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.1.4.12;3.1.4.38;3.1.4.-;3.1.4.3", "go_molecular_function": "GO:0046872 metal ion binding;GO:0004767 sphingomyelin phosphodiesterase activity;GO:0042802 identical protein binding;GO:0001786 phosphatidylserine binding;GO:0070300 phosphatidic acid binding", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005576 extracellular region;GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0005783 endoplasmic reticulum", "go_biological_process": "GO:0006684 sphingomyelin metabolic process;GO:0006685 sphingomyelin catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MZY8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MYK9-1", "uniprot_id": "A0A3Q1MYK9_BOVIN", "mass": 139767.0, "length": 1302, "protein_name": "Palladin", "gene_name": "PALLD", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "PALLD", "gene_names_refseq": "", "protein_names_uniprotkb": "Palladin", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003779 actin binding;GO:0098632 cell-cell adhesion mediator activity", "go_cellular_component": "GO:0005925 focal adhesion;GO:0030027 lamellipodium;GO:0030426 growth cone;GO:0002102 podosome;GO:0001725 stress fiber", "go_biological_process": "GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007411 axon guidance;GO:0070593 dendrite self-avoidance", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MYK9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1N9E9-1", "uniprot_id": "A0A3Q1N9E9_BOVIN", "mass": 202712.0, "length": 1824, "protein_name": "Laminin subunit alpha-4", "gene_name": "LAMA4", "organism": "Bovine", "refseq_name": "laminin subunit alpha-4 precursor", "refseq_ac": "NP_001192894", "gene_names_uniprotkb": "LAMA4", "gene_names_refseq": "LAMA4", "protein_names_uniprotkb": "Laminin subunit alpha-4; Laminin-14 subunit alpha; Laminin-8 subunit alpha; Laminin-9 subunit alpha", "protein_names_refseq": "laminin subunit alpha-4 precursor; laminin, alpha 4", "tax_id": 9913, "disease": "", "pathway": " (bta:529670)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005102 signaling receptor binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0005604 basement membrane;GO:0005886 plasma membrane;GO:0031594 neuromuscular junction;GO:0045202 synapse", "go_biological_process": "GO:0007155 cell adhesion;GO:0030155 regulation of cell adhesion;GO:0030334 regulation of cell migration;GO:0045995 regulation of embryonic development;GO:0007165 signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1N9E9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MTS5-1", "uniprot_id": "A0A3Q1MTS5_BOVIN", "mass": 125180.0, "length": 1116, "protein_name": "Phospholipid-transporting ATPase", "gene_name": "ATP9A", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "ATP9A", "gene_names_refseq": "", "protein_names_uniprotkb": "Phospholipid-transporting ATPase; 7.6.2.1", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-936837)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "7.6.2.1", "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0140326 ATPase-coupled intramembrane lipid transporter activity;GO:0002020 protease binding", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0016020 membrane;GO:0005768 endosome;GO:0005886 plasma membrane;GO:0032588 trans-Golgi network membrane", "go_biological_process": "GO:0015914 phospholipid transport;GO:0006897 endocytosis;GO:0048812 neuron projection morphogenesis;GO:0045332 phospholipid translocation;GO:0006890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MTS5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1N4S8-1", "uniprot_id": "A0A3Q1N4S8_BOVIN", "mass": 86903.0, "length": 769, "protein_name": "Phosphodiesterase", "gene_name": "PDE1C", "organism": "Bovine", "refseq_name": "dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C isoform X1", "refseq_ac": "XP_024846855", "gene_names_uniprotkb": "PDE1C", "gene_names_refseq": "PDE1C", "protein_names_uniprotkb": "Phosphodiesterase; 3.1.4.-", "protein_names_refseq": "dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C isoform X1", "tax_id": 9913, "disease": "", "pathway": " (bta:526211); (R-BTA-111957)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.1.4.-;3.1.4.1;3.6.1.9;3.1.4.35;3.1.4.17;3.6.1.1;3.6.1.25;3.6.1.14", "go_molecular_function": "GO:0005516 calmodulin binding;GO:0046872 metal ion binding;GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity;GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity;GO:0004117 calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity", "go_cellular_component": "GO:0005764 lysosome;GO:0043025 neuronal cell body", "go_biological_process": "GO:0007165 signal transduction;GO:0141162 negative regulation of cAMP/PKA signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1N4S8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MTZ4-1", "uniprot_id": "A0A3Q1MTZ4_BOVIN", "mass": 139346.0, "length": 1249, "protein_name": "Adhesion G-protein coupled receptor G6", "gene_name": "ADGRG6", "organism": "Bovine", "refseq_name": "adhesion G-protein coupled receptor G6 isoform X2", "refseq_ac": "XP_005211056", "gene_names_uniprotkb": "ADGRG6", "gene_names_refseq": "ADGRG6", "protein_names_uniprotkb": "Adhesion G-protein coupled receptor G6; Developmentally regulated G-protein-coupled receptor; G-protein coupled receptor 126", "protein_names_refseq": "adhesion G-protein coupled receptor G6 isoform X2", "tax_id": 9913, "disease": "", "pathway": " (bta:534326); (R-BTA-9619665)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Adhesion G-protein coupled receptor (aGPCR) for steroid hormones, such as progesterone and 17alpha-hydroxyprogesterone (17OHP). Involved in many biological processes, such as myelination, sprouting angiogenesis, placenta, ear and cartilage development. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors, such as adenylate cyclase. ADGRG6 is coupled to G(i) G alpha proteins and mediates inhibition of adenylate cyclase. Also able to couple to G(q) G proteins. Involved in myelination of the peripheral nervous system: required for differentiation of promyelinating Schwann cells and for normal myelination of axons. Also acts as a regulator of body length and bone mass. Acts as a regulator of blood-brain barrier formation in the central nervous system vie its association with LRP1 and ITGB1., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0046872 metal ion binding;GO:0043236 laminin binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005737 cytoplasm;GO:0009986 cell surface", "go_biological_process": "GO:0007166 cell surface receptor signaling pathway;GO:0042552 myelination;GO:0007188 adenylate cyclase-modulating G protein-coupled receptor signaling pathway;GO:0014037 Schwann cell differentiation;GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MTZ4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1N1M4-1", "uniprot_id": "A0A3Q1N1M4_BOVIN", "mass": 270418.0, "length": 2390, "protein_name": "Acetyl-CoA carboxylase 1", "gene_name": "ACACA; ACACB", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "ACACA; ACACB; ACACA", "gene_names_refseq": "", "protein_names_uniprotkb": "Acetyl-CoA carboxylase 1; 6.4.1.2; ACC-alpha", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-196780); (R-BTA-200425); (R-BTA-75105)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Cytosolic enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the first and rate-limiting step of de novo fatty acid biosynthesis. This is a 2 steps reaction starting with the ATP-dependent carboxylation of the biotin carried by the biotin carboxyl carrier (BCC) domain followed by the transfer of the carboxyl group from carboxylated biotin to acetyl-CoA., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "6.4.1.2;2.7.11.1;2.7.11.31", "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0003989 acetyl-CoA carboxylase activity;GO:0042802 identical protein binding", "go_cellular_component": "GO:0005829 cytosol;GO:0005739 mitochondrion", "go_biological_process": "GO:0006633 fatty acid biosynthetic process;GO:2001295 malonyl-CoA biosynthetic process;GO:0051289 protein homotetramerization;GO:0006084 acetyl-CoA metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1N1M4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MME8-1", "uniprot_id": "A0A3Q1MME8_BOVIN", "mass": 52009.0, "length": 460, "protein_name": "Cysteine protease", "gene_name": "ATG4A", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "ATG4A", "gene_names_refseq": "", "protein_names_uniprotkb": "Cysteine protease; 3.4.22.-", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-1632852)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.4.22.-", "go_molecular_function": "GO:0008234 cysteine-type peptidase activity;GO:0019786 protein-phosphatidylethanolamide deconjugating activity;GO:0004197 cysteine-type endopeptidase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0006508 proteolysis;GO:0015031 protein transport;GO:0006914 autophagy;GO:0006629 lipid metabolic process;GO:0000045 autophagosome assembly", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MME8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1NGK6-1", "uniprot_id": "A0A3Q1NGK6_BOVIN", "mass": 78749.0, "length": 696, "protein_name": "Methylenetetrahydrofolate reductase", "gene_name": "MTHFR", "organism": "Bovine", "refseq_name": "methylenetetrahydrofolate reductase (NADPH) isoform X1", "refseq_ac": "XP_005216989", "gene_names_uniprotkb": "MTHFR", "gene_names_refseq": "MTHFR", "protein_names_uniprotkb": "Methylenetetrahydrofolate reductase; 1.5.1.53", "protein_names_refseq": "methylenetetrahydrofolate reductase (NADPH) isoform X1", "tax_id": 9913, "disease": "", "pathway": " (bta:497032); (R-BTA-196757)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a cosubstrate for homocysteine remethylation to methionine. Represents a key regulatory connection between the folate and methionine cycles., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.5.1.53", "go_molecular_function": "GO:0106313 methylenetetrahydrofolate reductase (NADPH) activity;GO:0071949 FAD binding;GO:0044877 protein-containing complex binding;GO:0004489 methylenetetrahydrofolate reductase [NAD(P)H] activity;GO:0072341 modified amino acid binding", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0035999 tetrahydrofolate interconversion;GO:0006555 methionine metabolic process;GO:0009086 methionine biosynthetic process;GO:0050667 homocysteine metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1NGK6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1NC60-1", "uniprot_id": "A0A3Q1NC60_BOVIN", "mass": 137081.0, "length": 1240, "protein_name": "Zinc finger MYND-type containing 8", "gene_name": "ZMYND8", "organism": "Bovine", "refseq_name": "MYND-type zinc finger-containing chromatin reader ZMYND8 isoform X6", "refseq_ac": "XP_005214626", "gene_names_uniprotkb": "ZMYND8", "gene_names_refseq": "ZMYND8", "protein_names_uniprotkb": "Zinc finger MYND-type containing 8", "protein_names_refseq": "MYND-type zinc finger-containing chromatin reader ZMYND8 isoform X6", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-9940951)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0140006 histone H3 reader activity;GO:0019904 protein domain specific binding;GO:0003714 transcription corepressor activity;GO:0140015 histone H3K14ac reader activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005694 chromosome;GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045892 negative regulation of DNA-templated transcription;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0007399 nervous system development;GO:0030336 negative regulation of cell migration", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1NC60-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1NBH6-1", "uniprot_id": "A0A3Q1NBH6_BOVIN", "mass": 74199.0, "length": 674, "protein_name": "glutaminase", "gene_name": "GLS", "organism": "Bovine", "refseq_name": "glutaminase kidney isoform, mitochondrial isoform X1", "refseq_ac": "XP_005202636", "gene_names_uniprotkb": "GLS", "gene_names_refseq": "GLS", "protein_names_uniprotkb": "glutaminase; 3.5.1.2", "protein_names_refseq": "glutaminase kidney isoform, mitochondrial isoform X1", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.5.1.2;6.3.4.16;2.1.3.2;3.5.2.3;6.3.5.5", "go_molecular_function": "GO:0004359 glutaminase activity", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0006541 glutamine metabolic process;GO:0051289 protein homotetramerization;GO:0006537 glutamate biosynthetic process;GO:0006543 L-glutamine catabolic process;GO:0090461 intracellular glutamate homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1NBH6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q7SIH1-1", "uniprot_id": "A2MG_BOVIN", "mass": 167576.0, "length": 1510, "protein_name": "Alpha-2-macroglobulin", "gene_name": "A2M", "organism": "Bovine", "refseq_name": "alpha-2-macroglobulin precursor", "refseq_ac": "NP_001103265", "gene_names_uniprotkb": "A2M", "gene_names_refseq": "A2M", "protein_names_uniprotkb": "Alpha-2-macroglobulin; Alpha-2-M", "protein_names_refseq": "alpha-2-M; alpha-2-macroglobulin precursor", "tax_id": 9913, "disease": "", "pathway": " (bta:513856)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "12631277;14715656;15001551;22923050;22949401;25237709;30573663;9634697", "class_list": "", "function": "Alpha2-macroglobulin is a substrate and an endogenous inhibitor for ADAMTS-4 and ADAMTS-5, [RefSeq, PubMed]; Amounts of alpha(2)-M receptor in granulosa cells were strongly inversely associated with concentrations of estradiol in dominant and subordinate follicles., [RefSeq, PubMed]; Exon 29 c.3535A>T in the alpha-2-macroglobulin gene causing aberrant splice variants is associated with mastitis., [RefSeq, PubMed]; Is able to inhibit all four classes of proteinases by a unique 'trapping' mechanism. This protein has a peptide stretch, called the 'bait region' which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region, a conformational change is induced in the protein which traps the proteinase. The entrapped enzyme remains active against low molecular weight substrates (activity against high molecular weight substrates is greatly reduced). Following cleavage in the bait region a thioester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase (By similarity)., [UniProtKB]; Mutations in the promoter region and the 3'-untranslated region of the A2M gene are involved in the mastitis susceptibility in dairy cows., [RefSeq, PubMed]; These results suggest the possible involvement of cathepsin E in disruption of the structural and functional integrity of alpha 2-macroglobulin in the endolysosome system., [RefSeq, PubMed]; We report here for the first time the direct isolation of Spp24 covalently bound to alpha2-macroglobulins as a core complex (Spp24-alpha2M) from bovine calf serum., [RefSeq, PubMed]", "predicted_glycosites": 6, "predicted_n_glycosites": 5, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 1, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 1, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 1, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 7, "binding_glycan_count": 0, "secondary_ac_list": "A8E647", "ec_number_list": "", "go_molecular_function": "GO:0002020 protease binding;GO:0004867 serine-type endopeptidase inhibitor activity;GO:0004866 endopeptidase inhibitor activity;GO:0005102 signaling receptor binding;GO:0019959 interleukin-8 binding", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0001869 negative regulation of complement activation, lectin pathway", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "Q7SIH1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MRU9-1", "uniprot_id": "A0A3Q1MRU9_BOVIN", "mass": 66275.0, "length": 575, "protein_name": "Immunoglobulin like domain containing receptor 1", "gene_name": "ILDR1", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "ILDR1", "gene_names_refseq": "", "protein_names_uniprotkb": "Immunoglobulin like domain containing receptor 1", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0070506 high-density lipoprotein particle receptor activity;GO:0042802 identical protein binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005923 bicellular tight junction;GO:0012505 endomembrane system;GO:0032991 protein-containing complex;GO:0061689 tricellular tight junction", "go_biological_process": "GO:0061833 protein localization to tricellular tight junction;GO:1904274 tricellular tight junction assembly;GO:0043484 regulation of RNA splicing;GO:0070542 response to fatty acid;GO:0010669 epithelial structure maintenance", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MRU9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1N141-1", "uniprot_id": "A0A3Q1N141_BOVIN", "mass": 122668.0, "length": 1102, "protein_name": "Kinesin family member 1C", "gene_name": "KIF1C", "organism": "Bovine", "refseq_name": "kinesin-like protein KIF1C", "refseq_ac": "NP_001192731", "gene_names_uniprotkb": "KIF1C", "gene_names_refseq": "KIF1C", "protein_names_uniprotkb": "Kinesin family member 1C", "protein_names_refseq": "kinesin-like protein KIF1C", "tax_id": 9913, "disease": "", "pathway": " (bta:514928)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "30067756", "class_list": "", "function": "KIF1C bovine mutation leads to a functional knock-out, therefore mimicking mutations in humans affected by spastic paraplegia type 58/spastic ataxia 2. This model highlights the role of KIF1C protein in preserving the structural integrity and function of myelin, since the clinical signs and lesions arise in young-adult Charolais cattle. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0008017 microtubule binding;GO:0003777 microtubule motor activity;GO:0016887 ATP hydrolysis activity;GO:0008574 plus-end-directed microtubule motor activity", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0005874 microtubule;GO:0005737 cytoplasm;GO:0030424 axon;GO:0030425 dendrite", "go_biological_process": "GO:0007018 microtubule-based movement;GO:0016192 vesicle-mediated transport;GO:1990049 retrograde neuronal dense core vesicle transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A3Q1N141-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q58DC5-1", "uniprot_id": "GTPB1_BOVIN", "mass": 72585.0, "length": 669, "protein_name": "GTP-binding protein 1", "gene_name": "GTPBP1", "organism": "Bovine", "refseq_name": "GTP-binding protein 1", "refseq_ac": "NP_001017938", "gene_names_uniprotkb": "GTPBP1", "gene_names_refseq": "GTPBP1", "protein_names_uniprotkb": "GTP-binding protein 1; 3.6.5.3", "protein_names_refseq": "GTP-binding protein 1", "tax_id": 9913, "disease": "", "pathway": " (bta:513922)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "GTPase that plays a role in the elongation phase of protein synthesis by forming ternary complexes with GTP and aminoacyl-transfer RNAs (aa-tRNAs), and delivering aa-tRNAs to the ribosomal A site in a GTP-dependent manner. Is also able to deliver deacylated tRNA to the A site. Additionally, it is involved in RNA quality control; after GTP hydrolysis, which is not immediately followed by rapid peptide bond formation, GTPBP1 likely retains aa-tRNA in the A site and promotes exosomal degradation of faulty mRNAs engaged in 80S elongation complexes. Plays a role in the regulation of circadian mRNA stability., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 9, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.6.5.2;3.6.5.5;3.6.5.-;3.6.5.3;2.7.11.1;3.6.1.5;3.6.1.15;3.6.5.4", "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0000049 tRNA binding;GO:0003746 translation elongation factor activity;GO:1904678 alpha-aminoacyl-tRNA binding", "go_cellular_component": "GO:0005829 cytosol;GO:0000177 cytoplasmic exosome (RNase complex);GO:0005737 cytoplasm", "go_biological_process": "GO:0071025 RNA surveillance;GO:0046039 GTP metabolic process;GO:0061014 positive regulation of mRNA catabolic process;GO:0006414 translational elongation;GO:0002181 cytoplasmic translation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q58DC5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MW97-1", "uniprot_id": "A0A3Q1MW97_BOVIN", "mass": 115946.0, "length": 1014, "protein_name": "Anoctamin", "gene_name": "ANO1", "organism": "Bovine", "refseq_name": "anoctamin-1 isoform X4", "refseq_ac": "XP_059738947", "gene_names_uniprotkb": "ANO1", "gene_names_refseq": "ANO1; TMEM16A", "protein_names_uniprotkb": "Anoctamin", "protein_names_refseq": "anoctamin-1 isoform X4", "tax_id": 9913, "disease": "", "pathway": " (bta:532126)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0046983 protein dimerization activity;GO:0042802 identical protein binding;GO:0005227 calcium-activated cation channel activity;GO:0005229 intracellularly calcium-gated chloride channel activity;GO:0015111 iodide transmembrane transporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016324 apical plasma membrane", "go_biological_process": "GO:0070254 mucus secretion;GO:0072657 protein localization to membrane", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MW97-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MN33-1", "uniprot_id": "A0A3Q1MN33_BOVIN", "mass": 73319.0, "length": 644, "protein_name": "Glutamate--cysteine ligase", "gene_name": "GCLC", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "GCLC", "gene_names_refseq": "", "protein_names_uniprotkb": "Glutamate--cysteine ligase; 6.3.2.2; Gamma-ECS; Gamma-glutamylcysteine synthetase", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (bta:512468); (R-BTA-174403)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalyzes the ATP-dependent ligation of L-glutamate and L-cysteine and participates in the first and rate-limiting step in glutathione biosynthesis., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "6.3.2.2", "go_molecular_function": "GO:0005524 ATP binding;GO:0004357 glutamate-cysteine ligase activity;GO:0000287 magnesium ion binding;GO:0043531 ADP binding;GO:0016595 glutamate binding", "go_cellular_component": "GO:0017109 glutamate-cysteine ligase complex", "go_biological_process": "GO:0006750 glutathione biosynthetic process;GO:0043066 negative regulation of apoptotic process;GO:0006536 glutamate metabolic process;GO:0006979 response to oxidative stress;GO:0045892 negative regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MN33-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1N1F3-1", "uniprot_id": "A0A3Q1N1F3_BOVIN", "mass": 45633.0, "length": 402, "protein_name": "Glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)", "gene_name": "GCNT2", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "GCNT2", "gene_names_refseq": "", "protein_names_uniprotkb": "Glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (bta:520336)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0016757 glycosyltransferase activity;GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity;GO:0008375 acetylglucosaminyltransferase activity", "go_cellular_component": "GO:0000139 Golgi membrane", "go_biological_process": "GO:0030335 positive regulation of cell migration;GO:0051897 positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction;GO:0070374 positive regulation of ERK1 and ERK2 cascade;GO:0009101 glycoprotein biosynthetic process;GO:0010608 post-transcriptional regulation of gene expression", "synthesized_glycan_count": 2877, "hit_score": 0.1, "record_id": "A0A3Q1N1F3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3S5ZPR2-1", "uniprot_id": "A0A3S5ZPR2_BOVIN", "mass": 74300.0, "length": 650, "protein_name": "Maternal embryonic leucine zipper kinase", "gene_name": "MELK", "organism": "Bovine", "refseq_name": "maternal embryonic leucine zipper kinase isoform X1", "refseq_ac": "XP_024851491", "gene_names_uniprotkb": "MELK", "gene_names_refseq": "MELK", "protein_names_uniprotkb": "Maternal embryonic leucine zipper kinase; 2.7.10.2; 2.7.11.1; Protein kinase PK38; Tyrosine-protein kinase MELK", "protein_names_refseq": "maternal embryonic leucine zipper kinase isoform X1", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.11.1;2.7.11.25;2.7.11.24;2.7.11.22;2.7.11.13;2.7.11.23;2.7.12.1;2.7.12.2;2.7.11.17;2.7.11.39;2.7.10.2;2.7.1.150;2.7.11.12;2.7.11.31;2.7.11.26;2.7.11.21;2.7.1.153;2.7.1.137;2.7.1.154;4.1.1.32;2.7.11.38;2.7.11.11;3.1.11.-;2.7.4.6;2.7.13.3;2.7.4.18;3.1.24.-;2.7.11.-;2.7.11.4;2.7.2.3;2.7.11.10", "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0004715 non-membrane spanning protein tyrosine kinase activity;GO:0005524 ATP binding;GO:0008289 lipid binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0005938 cell cortex", "go_biological_process": "GO:0008283 cell population proliferation;GO:0006915 apoptotic process;GO:0035556 intracellular signal transduction;GO:0043065 positive regulation of apoptotic process;GO:0061351 neural precursor cell proliferation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3S5ZPR2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3ZC55-1", "uniprot_id": "ACTN2_BOVIN", "mass": 103779.0, "length": 894, "protein_name": "Alpha-actinin-2", "gene_name": "ACTN2", "organism": "Bovine", "refseq_name": "alpha-actinin-2", "refseq_ac": "NP_001029807", "gene_names_uniprotkb": "ACTN2", "gene_names_refseq": "ACTN2", "protein_names_uniprotkb": "Alpha-actinin-2; Alpha-actinin skeletal muscle isoform 2; F-actin cross-linking protein", "protein_names_refseq": "F-actin cross-linking protein; alpha-actinin skeletal muscle; alpha-actinin-2", "tax_id": 9913, "disease": "", "pathway": " (bta:536607); (R-BTA-114608); (R-BTA-390522); (R-BTA-438066); (R-BTA-5673001)", "pathway_count": 5, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003713 transcription coactivator activity;GO:0005546 phosphatidylinositol-4,5-bisphosphate binding;GO:0042802 identical protein binding;GO:0051015 actin filament binding;GO:0044325 transmembrane transporter binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005925 focal adhesion;GO:0030054 cell junction;GO:0030175 filopodium;GO:0030018 Z disc", "go_biological_process": "GO:0042391 regulation of membrane potential;GO:0072659 protein localization to plasma membrane;GO:0043268 positive regulation of potassium ion transport;GO:0030036 actin cytoskeleton organization;GO:0030035 microspike assembly", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q3ZC55-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3ZC24-1", "uniprot_id": "MARH5_BOVIN", "mass": 31232.0, "length": 278, "protein_name": "E3 ubiquitin-protein ligase MARCHF5", "gene_name": "MARCHF5", "organism": "Bovine", "refseq_name": "E3 ubiquitin-protein ligase MARCHF5", "refseq_ac": "NP_001029887", "gene_names_uniprotkb": "MARCHF5; MARCH5", "gene_names_refseq": "MARCH5; MARCHF5", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase MARCHF5; 2.3.2.27; MARCH-V; Membrane-associated RING finger protein 5; Membrane-associated RING-CH protein V; RING-type E3 ubiquitin transferase MARCHF5", "protein_names_refseq": "E3 ubiquitin-protein ligase MARCH5; E3 ubiquitin-protein ligase MARCHF5; MARCH-V; RING-type E3 ubiquitin transferase MARCH5; RING-type E3 ubiquitin transferase MARCHF5; membrane-associated RING finger protein 5; membrane-associated RING-CH protein V; membrane-associated ring finger (C3HC4) 5", "tax_id": 9913, "disease": "", "pathway": " (bta:540937)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Mitochondrial E3 ubiquitin-protein ligase that plays a crucial role in the control of mitochondrial morphology by acting as a positive regulator of mitochondrial fission and as an important regulator of immune response. Plays a crucial role in maintaining mitochondrial homeostasis by regulating the dynamics of mitochondria through the ubiquitination of key proteins involved in fission and fusion such as FIS1, DNM1L and MFN1 (By similarity). Acts as a critical determinant of mitotic apoptosis through both MCL1-dependent and -independent pathways (By similarity). Turns off persistent immune signaling by degrading oligomeric complexes of retinoic acid-inducible gene I/DDX58 and mitochondrial antiviral-signaling protein/MAVS formed upon RNA virus infection. Promotes STING-mediated type-I interferon production via 'Lys-63'-linked ubiquitination of STING1 thereby preserving its activity and preventing the formation of inactive STING1 polymers. Plays also an essential role in the formation of PEX3-containing vesicles in the de novo biogenesis of peroxisomes from mitochondria. Acts as a regulator of NLRP3 inflammasome activation on the mitochondria by mediating the 'Lys-27'-linked polyubiquitination of NLRP3, positively regulating the NLRP3-NEK7 complex formation and NLRP3 oligomerization (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0051020 GTPase binding;GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0005741 mitochondrial outer membrane;GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0090140 regulation of mitochondrial fission;GO:0070585 protein localization to mitochondrion;GO:0000209 protein polyubiquitination;GO:0051865 protein autoubiquitination;GO:0070936 protein K48-linked ubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q3ZC24-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1N3K8-1", "uniprot_id": "A0A3Q1N3K8_BOVIN", "mass": 138452.0, "length": 1235, "protein_name": "Phosphorylase b kinase regulatory subunit", "gene_name": "PHKA2", "organism": "Bovine", "refseq_name": "phosphorylase b kinase regulatory subunit alpha, liver isoform", "refseq_ac": "NP_001178474", "gene_names_uniprotkb": "PHKA2", "gene_names_refseq": "PHKA2", "protein_names_uniprotkb": "Phosphorylase b kinase regulatory subunit", "protein_names_refseq": "phosphorylase b kinase regulatory subunit alpha, liver isoform", "tax_id": 9913, "disease": "", "pathway": " (bta:515732); (R-BTA-70221)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The alpha chain may bind calmodulin., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005516 calmodulin binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0005964 phosphorylase kinase complex", "go_biological_process": "GO:0005977 glycogen metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1N3K8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MQ82-1", "uniprot_id": "A0A3Q1MQ82_BOVIN", "mass": 43151.0, "length": 389, "protein_name": "Protein Wnt", "gene_name": "WNT7B", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "WNT7B", "gene_names_refseq": "", "protein_names_uniprotkb": "Protein Wnt", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-3238698)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Ligand for members of the frizzled family of seven transmembrane receptors that functions in the canonical Wnt/beta-catenin signaling pathway. Required for normal fusion of the chorion and the allantois during placenta development. Required for central nervous system (CNS) angiogenesis and blood-brain barrier regulation., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005109 frizzled binding;GO:0005125 cytokine activity;GO:0048018 receptor ligand activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005576 extracellular region", "go_biological_process": "GO:0046330 positive regulation of JNK cascade;GO:0030182 neuron differentiation;GO:0060070 canonical Wnt signaling pathway;GO:0009888 tissue development;GO:0048513 animal organ development", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MQ82-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3ZC31-1", "uniprot_id": "HEM0_BOVIN", "mass": 65137.0, "length": 587, "protein_name": "5-aminolevulinate synthase, erythroid-specific, mitochondrial", "gene_name": "ALAS2", "organism": "Bovine", "refseq_name": "5-aminolevulinate synthase, erythroid-specific, mitochondrial", "refseq_ac": "NP_001030275", "gene_names_uniprotkb": "ALAS2", "gene_names_refseq": "ALAS2", "protein_names_uniprotkb": "5-aminolevulinate synthase, erythroid-specific, mitochondrial; 2.3.1.37; 5-aminolevulinic acid synthase 2; ALAS-E; Delta-ALA synthase 2; Delta-aminolevulinate synthase 2", "protein_names_refseq": "5-aminolevulinate synthase, erythroid-specific, mitochondrial; 5-aminolevulinic acid synthase 2; ALAS-E; aminolevulinate, delta-, synthase 2 (sideroblastic/hypochromic anemia); delta-ALA synthase 2; delta-ALA synthetase 2; delta-aminolevulinate synthase 2", "tax_id": 9913, "disease": "", "pathway": " (bta:511791); (R-BTA-189451)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalyzes the pyridoxal 5'-phosphate (PLP)-dependent condensation of succinyl-CoA and glycine to form aminolevulinic acid (ALA), with CoA and CO2 as by-products. Contributes significantly to heme formation during erythropoiesis., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.3.1.37", "go_molecular_function": "GO:0030170 pyridoxal phosphate binding;GO:0003870 5-aminolevulinate synthase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane;GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0001666 response to hypoxia;GO:0006783 heme biosynthetic process;GO:0006782 protoporphyrinogen IX biosynthetic process;GO:0042541 hemoglobin biosynthetic process;GO:0030218 erythrocyte differentiation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q3ZC31-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q58DS7-1", "uniprot_id": "PON2_BOVIN", "mass": 39421.0, "length": 354, "protein_name": "Serum paraoxonase/arylesterase 2", "gene_name": "PON2", "organism": "Bovine", "refseq_name": "serum paraoxonase/arylesterase 2", "refseq_ac": "NP_001013606", "gene_names_uniprotkb": "PON2", "gene_names_refseq": "PON2", "protein_names_uniprotkb": "Serum paraoxonase/arylesterase 2; 3.1.1.2; 3.1.1.81; A-esterase 2; Aromatic esterase 2; PON 2; Serum aryldialkylphosphatase 2", "protein_names_refseq": "A-esterase 2; PON 2; aromatic esterase 2; serum aryldialkylphosphatase 2; serum paraoxonase/arylesterase 2", "tax_id": 9913, "disease": "", "pathway": " (bta:281417); (R-BTA-2142688)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "16305752;23758560", "class_list": "", "function": "Capable of hydrolyzing lactones and a number of aromatic carboxylic acid esters., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; The aim of this study was to evaluate expression of the natural anti-oxidants paraoxonase (PON) 1, 2 and 3 in granulosa cells and PON1 activity in follicular fluid and plasma of dairy cows., [RefSeq, PubMed]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "B2BIS6;Q148F7", "ec_number_list": "3.1.1.2;3.1.1.81", "go_molecular_function": "GO:0102007 acyl-L-homoserine-lactone lactonohydrolase activity;GO:0046872 metal ion binding;GO:0004064 arylesterase activity;GO:0042803 protein homodimerization activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0016020 membrane;GO:0005886 plasma membrane", "go_biological_process": "GO:0009636 response to toxic substance;GO:1901335 lactone catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q58DS7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1N427-1", "uniprot_id": "A0A3Q1N427_BOVIN", "mass": 59908.0, "length": 532, "protein_name": "Dimethylaniline monooxygenase [N-oxide-forming]", "gene_name": "FMO1", "organism": "Bovine", "refseq_name": "flavin-containing monooxygenase 1", "refseq_ac": "NP_001193128", "gene_names_uniprotkb": "FMO1", "gene_names_refseq": "FMO1", "protein_names_uniprotkb": "Dimethylaniline monooxygenase [N-oxide-forming]; 1.14.13.148; 1.14.13.8", "protein_names_refseq": "flavin containing monooxygenase 1; flavin-containing monooxygenase 1", "tax_id": 9913, "disease": "", "pathway": " (bta:508781); (R-BTA-1614558); (R-BTA-217271)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Broad spectrum monooxygenase that catalyzes the oxygenation of a wide variety of nitrogen- and sulfur-containing compounds including xenobiotics. Catalyzes the S-oxygenation of hypotaurine to produce taurine, an organic osmolyte involved in cell volume regulation as well as a variety of cytoprotective and developmental processes. In vitro, catalyzes the N-oxygenation of trimethylamine (TMA) to produce trimethylamine N-oxide (TMAO) and could therefore participate to the detoxification of this compound that is generated by the action of gut microbiota from dietary precursors such as choline, choline containing compounds, betaine or L-carnitine., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.-.-.-;1.14.13.148;1.14.13.8;1.14.13.32", "go_molecular_function": "GO:0050660 flavin adenine dinucleotide binding;GO:0034899 trimethylamine monooxygenase activity;GO:0050661 NADP binding;GO:0004499 N,N-dimethylaniline monooxygenase activity;GO:0047822 hypotaurine monooxygenase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0009404 toxin metabolic process;GO:0042412 taurine biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1N427-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1NEK7-1", "uniprot_id": "A0A3Q1NEK7_BOVIN", "mass": 53679.0, "length": 463, "protein_name": "Glycine receptor alpha 3", "gene_name": "GLRA3", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "GLRA3", "gene_names_refseq": "", "protein_names_uniprotkb": "Glycine receptor alpha 3", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-112314)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "5.6.1.6;1.8.-.-;1.8.5.1", "go_molecular_function": "GO:0016934 extracellularly glycine-gated chloride channel activity;GO:0022824 transmitter-gated monoatomic ion channel activity;GO:0004888 transmembrane signaling receptor activity;GO:0016594 glycine binding;GO:0022852 glycine-gated chloride ion channel activity", "go_cellular_component": "GO:0045211 postsynaptic membrane;GO:0034707 chloride channel complex;GO:0042995 cell projection;GO:0016935 glycine-gated chloride channel complex;GO:0042734 presynaptic membrane", "go_biological_process": "GO:0051260 protein homooligomerization;GO:1902476 chloride transmembrane transport;GO:0099171 presynaptic modulation of chemical synaptic transmission", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1NEK7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q5BIM8-1", "uniprot_id": "ERCC8_BOVIN", "mass": 44113.0, "length": 397, "protein_name": "DNA excision repair protein ERCC-8", "gene_name": "ERCC8", "organism": "Bovine", "refseq_name": "DNA excision repair protein ERCC-8", "refseq_ac": "NP_001103651", "gene_names_uniprotkb": "ERCC8", "gene_names_refseq": "ERCC8", "protein_names_uniprotkb": "DNA excision repair protein ERCC-8", "protein_names_refseq": "DNA excision repair protein ERCC-8; excision repair cross-complementing rodent repair deficiency, complementation group 8", "tax_id": 9913, "disease": "", "pathway": " (bta:518857); (R-BTA-6781823); (R-BTA-6782135); (R-BTA-6782210); (R-BTA-8951664)", "pathway_count": 5, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "Substrate-recognition component of the CSA complex, a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex, involved in transcription-coupled nucleotide excision repair (TC-NER), a process during which RNA polymerase II-blocking lesions are rapidly removed from the transcribed strand of active genes. Following recruitment to lesion-stalled RNA polymerase II (Pol II), the CSA complex mediates ubiquitination of Pol II subunit POLR2A/RPB1 at 'Lys-1268', a critical TC-NER checkpoint, governing RNA Pol II stability and initiating DNA damage excision by TFIIH recruitment. The CSA complex also promotes the ubiquitination and subsequent proteasomal degradation of ERCC6/CSB in a UV-dependent manner; ERCC6 degradation is essential for the recovery of RNA synthesis after transcription-coupled repair. Also plays a role in DNA double-strand breaks (DSSBs) repair by non-homologous end joining (NHEJ)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:1990756 ubiquitin-like ligase-substrate adaptor activity", "go_cellular_component": "GO:0031464 Cul4A-RING E3 ubiquitin ligase complex;GO:0000109 nucleotide-excision repair complex;GO:0005634 nucleus;GO:0016363 nuclear matrix;GO:0032991 protein-containing complex", "go_biological_process": "GO:0097680 double-strand break repair via classical nonhomologous end joining;GO:0006979 response to oxidative stress;GO:0006974 DNA damage response;GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0045739 positive regulation of DNA repair", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q5BIM8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3ZBL0-1", "uniprot_id": "RUXG_BOVIN", "mass": 8496.0, "length": 76, "protein_name": "Small nuclear ribonucleoprotein G", "gene_name": "SNRPG", "organism": "Bovine", "refseq_name": "small nuclear ribonucleoprotein G", "refseq_ac": "NP_001035633", "gene_names_uniprotkb": "SNRPG", "gene_names_refseq": "SNRPG", "protein_names_uniprotkb": "Small nuclear ribonucleoprotein G; Sm protein G; Sm-G; SmG; snRNP-G", "protein_names_refseq": "sm protein G; sm-G; smG; small nuclear ribonucleoprotein G; snRNP-G", "tax_id": 9913, "disease": "", "pathway": " (bta:107131494); (bta:522621); (R-BTA-111367); (R-BTA-191859); (R-BTA-72163); (R-BTA-72165); (R-BTA-73856); (R-BTA-77588); (R-BTA-9770562); (R-BTA-9943411)", "pathway_count": 10, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs. As part of the U7 snRNP it is involved in histone 3'-end processing., [UniProtKB, UniProtKB]; Plays role in pre-mRNA splicing as core component of the SMN-Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding", "go_cellular_component": "GO:0005685 U1 snRNP;GO:0005634 nucleus;GO:0005829 cytosol;GO:0034709 methylosome;GO:0071013 catalytic step 2 spliceosome", "go_biological_process": "GO:0000387 spliceosomal snRNP assembly;GO:0000398 mRNA splicing, via spliceosome", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q3ZBL0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q6IE77-1", "uniprot_id": "NEIL2_BOVIN", "mass": 36392.0, "length": 329, "protein_name": "Endonuclease 8-like 2", "gene_name": "NEIL2", "organism": "Bovine", "refseq_name": "endonuclease 8-like 2", "refseq_ac": "NP_001013021", "gene_names_uniprotkb": "NEIL2", "gene_names_refseq": "NEIL2", "protein_names_uniprotkb": "Endonuclease 8-like 2; 3.2.2.-; 4.2.99.18; DNA glycosylase/AP lyase Neil2; DNA-(apurinic or apyrimidinic site) lyase Neil2; Endonuclease VIII-like 2; NEH2; Nei homolog 2; Nei-like protein 2", "protein_names_refseq": "DNA glycosylase/AP lyase Neil2; DNA-(apurinic or apyrimidinic site) lyase Neil2; NEH2; endonuclease 8-like 2; endonuclease VIII-like 2; nei endonuclease VIII-like 2; nei homolog 2; nei like 2; nei-like protein 2", "tax_id": 9913, "disease": "", "pathway": " (bta:444987); (R-BTA-110329); (R-BTA-5649702)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "15025586", "class_list": "", "function": "Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Has DNA glycosylase activity towards 5-hydroxyuracil and other oxidized derivatives of cytosine with a preference for mismatched double-stranded DNA (DNA bubbles). Has low or no DNA glycosylase activity towards thymine glycol, 2-hydroxyadenine, hypoxanthine and 8-oxoguanine. Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "4.2.99.18;5.6.2.4;3.6.4.12;6.5.1.1;2.7.7.7;4.2.99.-;3.2.2.-", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0003684 damaged DNA binding;GO:0019104 DNA N-glycosylase activity;GO:0140078 class I DNA-(apurinic or apyrimidinic site) endonuclease activity;GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0072686 mitotic spindle", "go_biological_process": "GO:0006284 base-excision repair", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q6IE77-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1N5S1-1", "uniprot_id": "A0A3Q1N5S1_BOVIN", "mass": 126355.0, "length": 1125, "protein_name": "Replication factor C subunit 1", "gene_name": "RFC1", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "RFC1", "gene_names_refseq": "", "protein_names_uniprotkb": "Replication factor C subunit 1", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-110312); (R-BTA-110314); (R-BTA-110320); (R-BTA-174411); (R-BTA-5651801); (R-BTA-5655862); (R-BTA-5656121); (R-BTA-5656169); (R-BTA-5685942); (R-BTA-5693537); (R-BTA-5696397); (R-BTA-5696400); (R-BTA-6782135); (R-BTA-6782210); (R-BTA-69091)", "pathway_count": 15, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Subunit of the replication factor C (RFC) complex which acts during elongation of primed DNA templates by DNA polymerases delta and epsilon, and is necessary for ATP-dependent loading of proliferating cell nuclear antigen (PCNA) onto primed DNA. This subunit binds to the primer-template junction. Binds the PO-B transcription element as well as other GA rich DNA sequences. Can bind single- or double-stranded DNA., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0003689 DNA clamp loader activity;GO:0061860 DNA clamp unloader activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005663 DNA replication factor C complex;GO:0005654 nucleoplasm;GO:0031391 Elg1 RFC-like complex", "go_biological_process": "GO:0006281 DNA repair;GO:0006260 DNA replication;GO:0006261 DNA-templated DNA replication", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1N5S1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3S5ZP34-1", "uniprot_id": "A0A3S5ZP34_BOVIN", "mass": 80961.0, "length": 714, "protein_name": "NADPH--cytochrome P450 reductase", "gene_name": "POR", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "POR", "gene_names_refseq": "", "protein_names_uniprotkb": "NADPH--cytochrome P450 reductase; 1.6.2.4; CPR; P450R", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5., [UniProtKB, HAMAP, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.6.2.4", "go_molecular_function": "GO:0050660 flavin adenine dinucleotide binding;GO:0010181 FMN binding;GO:0050661 NADP binding;GO:0003958 NADPH-hemoprotein reductase activity;GO:0008047 enzyme activator activity", "go_cellular_component": "GO:0005829 cytosol;GO:0005789 endoplasmic reticulum membrane;GO:0005654 nucleoplasm", "go_biological_process": "GO:0009725 response to hormone;GO:0006809 nitric oxide biosynthetic process;GO:0022900 electron transport chain;GO:0090346 organofluorine metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3S5ZP34-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q6T8E9-1", "uniprot_id": "CCNT1_BOVIN", "mass": 81307.0, "length": 727, "protein_name": "Cyclin-T1", "gene_name": "CCNT1", "organism": "Bovine", "refseq_name": "cyclin-T1", "refseq_ac": "NP_001001147", "gene_names_uniprotkb": "CCNT1", "gene_names_refseq": "CCNT1", "protein_names_uniprotkb": "Cyclin-T1; CycT1", "protein_names_refseq": "cycT1; cyclin-T1", "tax_id": 9913, "disease": "", "pathway": " (bta:407194); (R-BTA-112382); (R-BTA-2173796); (R-BTA-674695); (R-BTA-6796648); (R-BTA-6807505); (R-BTA-75955); (R-BTA-9018519)", "pathway_count": 8, "publication_count": 1, "publication_id_list": "14972556", "class_list": "", "function": "Regulatory subunit of the cyclin-dependent kinase pair (CDK9/cyclin-T1) complex, also called positive transcription elongation factor B (P-TEFb), which facilitates the transition from abortive to productive elongation by phosphorylating the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNA Pol II). Required to activate the protein kinase activity of CDK9: acts by mediating formation of liquid-liquid phase separation (LLPS) that enhances binding of P-TEFb to the CTD of RNA Pol II., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003682 chromatin binding;GO:0019901 protein kinase binding;GO:0000976 transcription cis-regulatory region binding;GO:0070063 RNA polymerase binding;GO:0097322 7SK snRNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0008024 cyclin/CDK positive transcription elongation factor complex;GO:0070691 P-TEFb complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0051301 cell division;GO:0043923 host-mediated activation of viral transcription;GO:0032968 positive regulation of transcription elongation by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q6T8E9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1N5T1-1", "uniprot_id": "A0A3Q1N5T1_BOVIN", "mass": 90933.0, "length": 827, "protein_name": "Enhancer of filamentation 1", "gene_name": "NEDD9", "organism": "Bovine", "refseq_name": "enhancer of filamentation 1 isoform X3", "refseq_ac": "XP_005223904", "gene_names_uniprotkb": "NEDD9", "gene_names_refseq": "NEDD9", "protein_names_uniprotkb": "Enhancer of filamentation 1; CRK-associated substrate-related protein; Neural precursor cell expressed developmentally down-regulated protein 9; p105", "protein_names_refseq": "enhancer of filamentation 1 isoform X3", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:1990782 protein tyrosine kinase binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0042995 cell projection;GO:0000922 spindle pole;GO:0005654 nucleoplasm;GO:0005794 Golgi apparatus", "go_biological_process": "GO:0007155 cell adhesion;GO:0007169 cell surface receptor protein tyrosine kinase signaling pathway;GO:0007611 learning or memory;GO:0016477 cell migration;GO:0032956 regulation of actin cytoskeleton organization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1N5T1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3ZBH9-1", "uniprot_id": "MCM7_BOVIN", "mass": 81315.0, "length": 719, "protein_name": "DNA replication licensing factor MCM7", "gene_name": "MCM7", "organism": "Bovine", "refseq_name": "DNA replication licensing factor MCM7", "refseq_ac": "NP_001020516", "gene_names_uniprotkb": "MCM7", "gene_names_refseq": "MCM7", "protein_names_uniprotkb": "DNA replication licensing factor MCM7; 3.6.4.12", "protein_names_refseq": "DNA replication licensing factor MCM7; MCM7 minichromosome maintenance deficient 7; minichromosome maintenance protein 7", "tax_id": 9913, "disease": "", "pathway": " (bta:539924); (R-BTA-176187); (R-BTA-68867); (R-BTA-68949); (R-BTA-68962); (R-BTA-69052)", "pathway_count": 6, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Acts as a component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. Core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for S-phase checkpoint activation upon UV-induced damage., [UniProtKB, UniProtKB]; Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.6.4.12;5.6.2.4;3.6.4.13;2.3.2.27;7.2.2.-;2.7.7.7;2.7.7.49;3.6.1.5;2.7.7.-;3.6.4.6;3.6.4.10;5.6.2.3;3.6.5.-;5.6.2.-;2.7.4.3;3.6.4.-;2.7.11.1;3.1.-.-;4.2.99.18;5.6.1.6;3.6.1.15;7.6.2.1;3.1.3.1;3.9.1.1;5.6.2.5;3.4.24.-;3.6.-.-;3.6.1.-;5.6.1.7;3.1.4.-;3.4.21.53;2.7.11.22", "go_molecular_function": "GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0003697 single-stranded DNA binding;GO:0003678 DNA helicase activity;GO:0016787 hydrolase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0042555 MCM complex;GO:0071162 CMG complex;GO:0005694 chromosome", "go_biological_process": "GO:0006271 DNA strand elongation involved in DNA replication;GO:0008283 cell population proliferation;GO:0006260 DNA replication;GO:0006974 DNA damage response;GO:0006270 DNA replication initiation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q3ZBH9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A452DHY1-1", "uniprot_id": "A0A452DHY1_BOVIN", "mass": 45217.0, "length": 391, "protein_name": "Neutrophil cytosolic factor 1", "gene_name": "NCF1", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "NCF1", "gene_names_refseq": "", "protein_names_uniprotkb": "Neutrophil cytosolic factor 1", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-1222556); (R-BTA-1236973); (R-BTA-3299685); (R-BTA-4420097); (R-BTA-5668599); (R-BTA-9013404); (R-BTA-9013423)", "pathway_count": 7, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0035091 phosphatidylinositol binding;GO:0016176 superoxide-generating NADPH oxidase activator activity;GO:0017124 SH3 domain binding;GO:0043325 phosphatidylinositol-3,4-bisphosphate binding;GO:0016175 superoxide-generating NAD(P)H oxidase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0016020 membrane;GO:0043020 NADPH oxidase complex;GO:0005829 cytosol;GO:0009898 cytoplasmic side of plasma membrane", "go_biological_process": "GO:0072593 reactive oxygen species metabolic process;GO:0006612 protein targeting to membrane;GO:0045730 respiratory burst;GO:0042554 superoxide anion generation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A452DHY1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q865V6-1", "uniprot_id": "CAPG_BOVIN", "mass": 38876.0, "length": 349, "protein_name": "Macrophage-capping protein", "gene_name": "CAPG", "organism": "Bovine", "refseq_name": "macrophage-capping protein", "refseq_ac": "NP_848669", "gene_names_uniprotkb": "CAPG", "gene_names_refseq": "CAPG", "protein_names_uniprotkb": "Macrophage-capping protein; Actin regulatory protein CAP-G", "protein_names_refseq": "actin regulatory protein CAP-G; capping protein (actin filament), gelsolin-like; macrophage-capping protein", "tax_id": 9913, "disease": "", "pathway": " (bta:353121)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "12754261", "class_list": "", "function": "Calcium-sensitive protein which reversibly blocks the barbed ends of actin filaments but does not sever preformed actin filaments. May play an important role in macrophage function. May play a role in regulating cytoplasmic and/or nuclear structures through potential interactions with actin. May bind DNA (By similarity)., [UniProtKB]; Observations suggest that macrophage capping protein(Cap G) may contribute to the protective effect exerted by plaque-free flow on endothelial cells, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005546 phosphatidylinositol-4,5-bisphosphate binding;GO:0051015 actin filament binding;GO:0019904 protein domain specific binding", "go_cellular_component": "GO:0005634 nucleus;GO:0015629 actin cytoskeleton;GO:0030027 lamellipodium;GO:0042470 melanosome;GO:0001726 ruffle", "go_biological_process": "GO:0007417 central nervous system development;GO:0051016 barbed-end actin filament capping;GO:0008154 actin polymerization or depolymerization;GO:0051014 actin filament severing;GO:0030031 cell projection assembly", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q865V6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3S5ZPW1-1", "uniprot_id": "A0A3S5ZPW1_BOVIN", "mass": 25139.0, "length": 224, "protein_name": "Neuroendocrine protein 7B2", "gene_name": "SCG5", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "SCG5", "gene_names_refseq": "", "protein_names_uniprotkb": "Neuroendocrine protein 7B2; Secretogranin-5", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Acts as a molecular chaperone for PCSK2/PC2, preventing its premature activation in the regulated secretory pathway. Binds to inactive PCSK2 in the endoplasmic reticulum and facilitates its transport from there to later compartments of the secretory pathway where it is proteolytically matured and activated. Also required for cleavage of PCSK2 but does not appear to be involved in its folding. Plays a role in regulating pituitary hormone secretion. The C-terminal peptide inhibits PCSK2 in vitro., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004857 enzyme inhibitor activity;GO:0051082 unfolded protein binding;GO:0030234 enzyme regulator activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0030141 secretory granule;GO:0005634 nucleus", "go_biological_process": "GO:0007218 neuropeptide signaling pathway;GO:0006886 intracellular protein transport;GO:0016486 peptide hormone processing;GO:0046883 regulation of hormone secretion", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3S5ZPW1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3S5ZPA0-1", "uniprot_id": "A0A3S5ZPA0_BOVIN", "mass": 89752.0, "length": 793, "protein_name": "Exostosin-2", "gene_name": "EXT2", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "EXT2", "gene_names_refseq": "", "protein_names_uniprotkb": "Exostosin-2; 2.4.1.224; Glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-2022928)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Glycosyltransferase forming with EXT1 the heterodimeric heparan sulfate polymerase which catalyzes the elongation of the heparan sulfate glycan backbone. Glycan backbone extension consists in the alternating transfer of (1->4)-beta-D-GlcA and (1->4)-alpha-D-GlcNAc residues from their respective UDP-sugar donors. Both EXT1 and EXT2 are required for the full activity of the polymerase since EXT1 bears the N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity within the complex while EXT2 carries the glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity. Heparan sulfate proteoglycans are ubiquitous components of the extracellular matrix and play an important role in tissue homeostasis and signaling., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.4.1.224;2.4.1.225", "go_molecular_function": "GO:0046872 metal ion binding;GO:0015020 glucuronosyltransferase activity;GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity;GO:0042803 protein homodimerization activity;GO:0046982 protein heterodimerization activity", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0005789 endoplasmic reticulum membrane;GO:0043541 UDP-N-acetylglucosamine transferase complex", "go_biological_process": "GO:0015012 heparan sulfate proteoglycan biosynthetic process;GO:0000271 polysaccharide biosynthetic process;GO:0001503 ossification;GO:0006024 glycosaminoglycan biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3S5ZPA0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1N0V2-1", "uniprot_id": "A0A3Q1N0V2_BOVIN", "mass": 315440.0, "length": 2848, "protein_name": "Teneurin-4", "gene_name": "TENM4", "organism": "Bovine", "refseq_name": "teneurin-4 isoform X2", "refseq_ac": "XP_024843296", "gene_names_uniprotkb": "TENM4", "gene_names_refseq": "TENM4", "protein_names_uniprotkb": "Teneurin-4; Protein Odd Oz/ten-m homolog 4; Tenascin-M4; Teneurin transmembrane protein 4", "protein_names_refseq": "teneurin-4 isoform X2", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Involved in neural development, regulating the establishment of proper connectivity within the nervous system. Plays a role in the establishment of the anterior-posterior axis during gastrulation. Regulates the differentiation and cellular process formation of oligodendrocytes and myelination of small-diameter axons in the central nervous system (CNS). Promotes activation of focal adhesion kinase. May function as a cellular signal transducer., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0042803 protein homodimerization activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0042995 cell projection;GO:0098978 glutamatergic synapse", "go_biological_process": "GO:0032289 central nervous system myelin formation;GO:0007165 signal transduction;GO:0031641 regulation of myelination;GO:0048714 positive regulation of oligodendrocyte differentiation;GO:0048666 neuron development", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1N0V2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MQS1-1", "uniprot_id": "A0A3Q1MQS1_BOVIN", "mass": 36540.0, "length": 317, "protein_name": "Non-structural maintenance of chromosomes element 1 homolog", "gene_name": "NSMCE1", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "NSMCE1", "gene_names_refseq": "", "protein_names_uniprotkb": "Non-structural maintenance of chromosomes element 1 homolog; 2.3.2.27", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-3108214)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "RING-type zinc finger-containing E3 ubiquitin ligase that assembles with melanoma antigen protein (MAGE) to catalyze the direct transfer of ubiquitin from E2 ubiquitin-conjugating enzyme to a specific substrate. Involved in maintenance of genome integrity, DNA damage response and DNA repair., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.3.2.27", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity;GO:0004842 ubiquitin-protein transferase activity;GO:0046983 protein dimerization activity", "go_cellular_component": "GO:0005634 nucleus;GO:0000781 chromosome, telomeric region;GO:0030915 Smc5-Smc6 complex;GO:0005654 nucleoplasm;GO:0000775 chromosome, centromeric region", "go_biological_process": "GO:0000724 double-strand break repair via homologous recombination;GO:0006281 DNA repair;GO:0006310 DNA recombination", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MQS1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MXU1-1", "uniprot_id": "A0A3Q1MXU1_BOVIN", "mass": 54875.0, "length": 477, "protein_name": "Septin 4", "gene_name": "SEPTIN4", "organism": "Bovine", "refseq_name": "septin-4 isoform X3", "refseq_ac": "XP_005219968", "gene_names_uniprotkb": "SEPTIN4", "gene_names_refseq": "SEPT4; SEPTIN4", "protein_names_uniprotkb": "Septin 4", "protein_names_refseq": "septin-4 isoform X3", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-111457); (R-BTA-111469)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Filament-forming cytoskeletal GTPase., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005525 GTP binding;GO:0060090 molecular adaptor activity;GO:0003924 GTPase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005856 cytoskeleton;GO:0097227 sperm annulus;GO:0005940 septin ring;GO:0015630 microtubule cytoskeleton", "go_biological_process": "GO:0051301 cell division;GO:0008104 intracellular protein localization;GO:0061640 cytoskeleton-dependent cytokinesis;GO:0017157 regulation of exocytosis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MXU1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MM17-1", "uniprot_id": "A0A3Q1MM17_BOVIN", "mass": 27574.0, "length": 243, "protein_name": "Homeobox B8", "gene_name": "HOXB8", "organism": "Bovine", "refseq_name": "homeobox protein Hox-B8 isoform X1", "refseq_ac": "XP_024836589", "gene_names_uniprotkb": "HOXB8", "gene_names_refseq": "HOXB8", "protein_names_uniprotkb": "Homeobox B8", "protein_names_refseq": "homeobox protein Hox-B8 isoform X1", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0045638 negative regulation of myeloid cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MM17-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MMF9-1", "uniprot_id": "A0A3Q1MMF9_BOVIN", "mass": 47327.0, "length": 417, "protein_name": "DNA methyltransferase 3 like", "gene_name": "DNMT3L", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "DNMT3L", "gene_names_refseq": "", "protein_names_uniprotkb": "DNA methyltransferase 3 like", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, 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silencing by piRNA-mediated DNA methylation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MMF9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MMI8-1", "uniprot_id": "A0A3Q1MMI8_BOVIN", "mass": 21580.0, "length": 189, "protein_name": "Uncharacterized protein", "gene_name": "LOC783912", "organism": "Bovine", "refseq_name": "interferon alpha-H", "refseq_ac": "XP_002689579", "gene_names_uniprotkb": "LOC783912", "gene_names_refseq": "LOC783912", "protein_names_uniprotkb": "Uncharacterized protein", "protein_names_refseq": "interferon alpha-H", "tax_id": 9913, "disease": "", "pathway": " (bta:783912); (R-BTA-909733); (R-BTA-912694)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005125 cytokine activity;GO:0005132 type I interferon receptor binding", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0002312 B cell activation involved in immune response;GO:0051607 defense response to virus;GO:0060337 type I interferon-mediated signaling pathway;GO:0002250 adaptive immune response;GO:0043330 response to exogenous dsRNA", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MMI8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MMP5-1", "uniprot_id": "A0A3Q1MMP5_BOVIN", "mass": 200141.0, "length": 1808, "protein_name": "Tuberin", "gene_name": "TSC2", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "TSC2", "gene_names_refseq": "", "protein_names_uniprotkb": "Tuberin", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalytic component of the TSC-TBC complex, a multiprotein complex that acts as a negative regulator of the canonical mTORC1 complex, an evolutionarily conserved central nutrient sensor that stimulates anabolic reactions and macromolecule biosynthesis to promote cellular biomass generation and growth. Within the TSC-TBC complex, TSC2 acts as a GTPase-activating protein (GAP) for the small GTPase RHEB, a direct activator of the protein kinase activity of mTORC1. In absence of nutrients, the TSC-TBC complex inhibits mTORC1, thereby preventing phosphorylation of ribosomal protein S6 kinase (RPS6KB1 and RPS6KB2) and EIF4EBP1 (4E-BP1) by the mTORC1 signaling. The TSC-TBC complex is inactivated in response to nutrients, relieving inhibition of mTORC1. Involved in microtubule-mediated protein transport via its ability to regulate mTORC1 signaling. Also stimulates the intrinsic GTPase activity of the Ras-related proteins RAP1A and RAB5., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005096 GTPase activator activity;GO:0042803 protein homodimerization activity;GO:0031267 small GTPase binding;GO:0051879 Hsp90 protein binding;GO:0019902 phosphatase binding", "go_cellular_component": "GO:0033596 TSC1-TSC2 complex;GO:0005634 nucleus;GO:0005794 Golgi apparatus;GO:0014069 postsynaptic density;GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "GO:0051056 regulation of small GTPase mediated signal transduction;GO:0016239 positive regulation of macroautophagy;GO:0009267 cellular response to starvation;GO:0043276 anoikis;GO:1904262 negative regulation of TORC1 signaling", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MMP5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MSS5-1", "uniprot_id": "A0A3Q1MSS5_BOVIN", "mass": 62657.0, "length": 568, "protein_name": "Protein kinase AMP-activated non-catalytic subunit gamma 2", "gene_name": "PRKAG2", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "PRKAG2", "gene_names_refseq": "", "protein_names_uniprotkb": "Protein kinase AMP-activated non-catalytic subunit gamma 2", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-1632852); (R-BTA-163680); (R-BTA-200425); (R-BTA-380972); (R-BTA-5628897); (R-BTA-6804756); (R-BTA-9931269)", "pathway_count": 7, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0019901 protein kinase binding;GO:0004862 cAMP-dependent protein kinase inhibitor activity;GO:0008607 phosphorylase kinase regulator activity;GO:0016208 AMP binding", "go_cellular_component": "GO:0005829 cytosol;GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0031588 nucleotide-activated protein kinase complex", "go_biological_process": "GO:0006633 fatty acid biosynthetic process;GO:0006110 regulation of glycolytic process;GO:0035556 intracellular signal transduction;GO:0005977 glycogen metabolic process;GO:0019217 regulation of fatty acid metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MSS5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MNQ1-1", "uniprot_id": "A0A3Q1MNQ1_BOVIN", "mass": 148369.0, "length": 1353, "protein_name": "Elongation factor 1-gamma", "gene_name": "EEF1G; TUT1", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "EEF1G; TUT1; TUT1", "gene_names_refseq": "", "protein_names_uniprotkb": "Elongation factor 1-gamma; 2.7.7.19; 2.7.7.52; RNA-binding motif protein 21; Speckle targeted PIP5K1A-regulated poly(A) polymerase; U6 snRNA-specific terminal uridylyltransferase 1; eEF-1B gamma", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-156842); (R-BTA-9770562)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Poly(A) polymerase that creates the 3'-poly(A) tail of specific pre-mRNAs. Localizes to nuclear speckles together with PIP5K1A and mediates polyadenylation of a select set of mRNAs, such as HMOX1. In addition to polyadenylation, it is also required for the 3'-end cleavage of pre-mRNAs: binds to the 3'UTR of targeted pre-mRNAs and promotes the recruitment and assembly of the CPSF complex on the 3'UTR of pre-mRNAs. In addition to adenylyltransferase activity, also has uridylyltransferase activity. However, the ATP ratio is higher than UTP in cells, suggesting that it functions primarily as a poly(A) polymerase. Acts as a specific terminal uridylyltransferase for U6 snRNA in vitro: responsible for a controlled elongation reaction that results in the restoration of the four 3'-terminal UMP-residues found in newly transcribed U6 snRNA. Not involved in replication-dependent histone mRNA degradation., [UniProtKB, UniProtKB, UniProtKB]; Probably plays a role in anchoring the complex to other cellular components., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.6.4.13;2.7.7.52;2.7.7.19;2.3.2.27;2.7.1.78;3.1.13.-;2.7.7.48;2.7.7.6;3.1.27.-;3.1.3.53;3.1.3.16", "go_molecular_function": "GO:0003723 RNA binding;GO:0005524 ATP binding;GO:0008270 zinc ion binding;GO:0003746 translation elongation factor activity;GO:0050265 RNA uridylyltransferase activity", "go_cellular_component": "GO:0005730 nucleolus;GO:0016607 nuclear speck;GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006397 mRNA processing;GO:0031123 RNA 3'-end processing;GO:0006414 translational elongation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MNQ1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MP25-1", "uniprot_id": "A0A3Q1MP25_BOVIN", "mass": 68190.0, "length": 620, "protein_name": "Complex I assembly factor ACAD9, mitochondrial", "gene_name": "ACAD9", "organism": "Bovine", "refseq_name": "complex I assembly factor ACAD9, mitochondrial isoform X1", "refseq_ac": "XP_024838811", "gene_names_uniprotkb": "ACAD9", "gene_names_refseq": "ACAD9", "protein_names_uniprotkb": "Complex I assembly factor ACAD9, mitochondrial; 1.3.8.7; 1.3.8.8; Acyl-CoA dehydrogenase family member 9", "protein_names_refseq": "complex I assembly factor ACAD9, mitochondrial isoform X1", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-6799198)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.3.8.7;1.3.8.8;2.1.1.320;7.1.1.2;1.3.8.9", "go_molecular_function": "GO:0003995 acyl-CoA dehydrogenase activity;GO:0050660 flavin adenine dinucleotide binding", "go_cellular_component": "GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0006631 fatty acid metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MP25-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3ZBD7-1", "uniprot_id": "G6PI_BOVIN", "mass": 62855.0, "length": 557, "protein_name": "Glucose-6-phosphate isomerase", "gene_name": "GPI", "organism": "Bovine", "refseq_name": "glucose-6-phosphate isomerase", "refseq_ac": "NP_001035561", "gene_names_uniprotkb": "GPI", "gene_names_refseq": "GPI", "protein_names_uniprotkb": "Glucose-6-phosphate isomerase; 5.1.3.-; 5.3.1.9; AMF; Autocrine motility factor; D-hexose-6-phosphate anomerase; GPI; Glucose-6-phosphate C2-epimerase; NLK; Neuroleukin; PGI; PHI; Phosphoglucose isomerase; Phosphohexose isomerase", "protein_names_refseq": "AMF; D-hexose-6-phosphate anomerase; NLK; PGI; PHI; autocrine motility factor; glucose phosphate isomerase; glucose-6-phosphate C2-epimerase; glucose-6-phosphate isomerase; glucosephosphate isomerase; neuroleukin; phosphoglucose isomerase; phosphohexose isomerase", "tax_id": 9913, "disease": "", "pathway": " (bta:280808); (R-BTA-5628897); (R-BTA-6798695); (R-BTA-70171); (R-BTA-70263)", "pathway_count": 5, "publication_count": 1, "publication_id_list": "19393038", "class_list": "", "function": "Isomerase that catalyzes the conversion of alpha-D-glucose-6-phosphate to beta-D-fructose-6-phosphate, the second step in glycolysis, and the reverse reaction in gluconeogenesis, within the cytoplasm. Also shows C2-epimerase activity, interconverting D-glucose-6-phosphate (G6P) and D-mannose-6-phosphate (M6P). Also displays anomerase activity, interconverting alpha and beta-anomeric forms of G6P, D-fructose-6-phosphate and M6P. In addition to its metabolic role, this enzyme functions extracellularly as a cytokine: acts as autocrine motility factor (AMF), a secreted angiogenic factor that enhances endothelial cell motility. Functions as neuroleukin, a neurotrophic factor supporting the survival of spinal and sensory neurons. Released by lectin-stimulated T-cells to induce immunoglobulin secretion., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "F1MD19;O46595", "ec_number_list": "1.1.1.42;2.5.1.18;2.7.1.1;2.7.11.24;3.2.1.23;2.4.2.1;5.2.1.8;4.1.2.13;3.6.1.6;2.3.2.27;3.1.6.14;3.6.4.13;1.1.1.205;2.7.1.11;2.7.11.22;2.7.11.23;2.3.2.26;2.4.1.25;3.2.1.33;4.2.99.18;5.6.2.4;3.6.4.12;3.4.23.5;1.13.11.34;1.13.11.12;3.6.4.6;1.16.3.1;1.11.1.6;3.4.18.1;3.4.22.1;3.6.4.10;3.4.22.27;3.4.24.35;3.6.5.-;3.1.1.47;5.3.2.1;5.3.3.12;3.4.19.1;2.7.1.35;2.4.1.1;3.5.1.23;3.5.1.-;3.4.22.52;2.3.3.8;5.4.2.11;5.4.2.4;3.3.2.6;3.4.11.4;3.4.21.46;2.7.4.6;2.7.13.3;4.1.2.4;5.3.1.9;5.1.3.-;3.6.1.-;2.4.2.7;4.2.1.24", "go_molecular_function": "GO:0005125 cytokine activity;GO:0004347 glucose-6-phosphate isomerase activity;GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives;GO:0097367 carbohydrate derivative binding;GO:0048029 monosaccharide binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005829 cytosol;GO:0005737 cytoplasm", "go_biological_process": "GO:0006094 gluconeogenesis;GO:0006096 glycolytic process;GO:0051156 glucose 6-phosphate metabolic process;GO:0010595 positive regulation of endothelial cell migration;GO:0006002 fructose 6-phosphate metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q3ZBD7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MPN0-1", "uniprot_id": "A0A3Q1MPN0_BOVIN", "mass": 79495.0, "length": 692, "protein_name": "Myotubularin related protein 7", "gene_name": "MTMR7", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "MTMR7", "gene_names_refseq": "", "protein_names_uniprotkb": "Myotubularin related protein 7", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0052866 phosphatidylinositol phosphate phosphatase activity", "go_cellular_component": "GO:0005829 cytosol;GO:0016020 membrane;GO:0012505 endomembrane system;GO:0005737 cytoplasm", "go_biological_process": "GO:0046856 phosphatidylinositol dephosphorylation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MPN0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3T0P6-1", "uniprot_id": "PGK1_BOVIN", "mass": 44538.0, "length": 417, "protein_name": "Phosphoglycerate kinase 1", "gene_name": "PGK1", "organism": "Bovine", "refseq_name": "phosphoglycerate kinase 1", "refseq_ac": "NP_001029471", "gene_names_uniprotkb": "PGK1", "gene_names_refseq": "PGK1", "protein_names_uniprotkb": "Phosphoglycerate kinase 1; 2.7.11.1; 2.7.2.3", "protein_names_refseq": "phosphoglycerate kinase 1", "tax_id": 9913, "disease": "", "pathway": " (bta:507476); (R-BTA-165159); (R-BTA-70171); (R-BTA-70263)", "pathway_count": 4, "publication_count": 2, "publication_id_list": "12488440;30573663", "class_list": "", "function": "Catalyzes one of the two ATP producing reactions in the glycolytic pathway via the reversible conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate. Both L- and D- forms of purine and pyrimidine nucleotides can be used as substrates, but the activity is much lower on pyrimidines. In addition to its role as a glycolytic enzyme, it seems that PGK-1 acts as a polymerase alpha cofactor protein (primer recognition protein). Acts as a protein kinase when localized to the mitochondrion where it phosphorylates pyruvate dehydrogenase kinase PDK1 to inhibit pyruvate dehydrogenase complex activity and suppress the formation of acetyl-coenzyme A from pyruvate, and consequently inhibit oxidative phosphorylation and promote glycolysis. May play a role in sperm motility., [UniProtKB, UniProtKB]; Present in, and accounts for, glycolysis and glutamate accumulation into synaptic vesicles, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.11.1;2.7.11.25;2.7.11.24;2.7.11.22;2.7.11.13;2.7.11.23;2.7.12.1;2.7.12.2;2.7.11.17;2.7.11.39;2.7.10.2;2.7.1.150;2.7.11.12;2.7.2.3;2.7.11.31;2.7.11.26;2.7.11.21;2.7.1.153;2.7.1.137;2.7.1.154;2.7.11.38;2.7.11.11;3.1.11.-;2.7.4.6;2.7.13.3;2.7.4.18;3.1.24.-;2.7.11.-;2.7.11.4;2.7.11.10", "go_molecular_function": "GO:0004618 phosphoglycerate kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0043531 ADP binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005759 mitochondrial matrix;GO:0005829 cytosol;GO:0045121 membrane raft", "go_biological_process": "GO:0030855 epithelial cell differentiation;GO:0071456 cellular response to hypoxia;GO:0006094 gluconeogenesis;GO:0016525 negative regulation of angiogenesis;GO:0006096 glycolytic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q3T0P6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MPT4-1", "uniprot_id": "A0A3Q1MPT4_BOVIN", "mass": 77154.0, "length": 700, "protein_name": "Mitogen-activated protein kinase 8 interacting protein 1", "gene_name": "MAPK8IP1", "organism": "Bovine", "refseq_name": "C-Jun-amino-terminal kinase-interacting protein 1 isoform X1", "refseq_ac": "XP_005216519", "gene_names_uniprotkb": "MAPK8IP1", "gene_names_refseq": "MAPK8IP1", "protein_names_uniprotkb": "Mitogen-activated protein kinase 8 interacting protein 1", "protein_names_refseq": "C-Jun-amino-terminal kinase-interacting protein 1 isoform X1", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0019901 protein kinase binding;GO:0019894 kinesin binding;GO:0005078 MAP-kinase scaffold activity;GO:0008432 JUN kinase binding", "go_cellular_component": "GO:0044302 dentate gyrus mossy fiber;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0030425 dendrite;GO:0045202 synapse", "go_biological_process": "GO:2000564 regulation of CD8-positive, alpha-beta T cell proliferation;GO:0046330 positive regulation of JNK cascade;GO:0007254 JNK cascade;GO:0046328 regulation of JNK cascade", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MPT4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MSD1-1", "uniprot_id": "A0A3Q1MSD1_BOVIN", "mass": 50788.0, "length": 465, "protein_name": "Meis homeobox 1", "gene_name": "MEIS1", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "MEIS1", "gene_names_refseq": "", "protein_names_uniprotkb": "Meis homeobox 1", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0003682 chromatin binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005667 transcription regulator complex", "go_biological_process": "GO:0006355 regulation of DNA-templated transcription;GO:0001525 angiogenesis;GO:0008284 positive regulation of cell population proliferation;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0007420 brain development", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MSD1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MS15-1", "uniprot_id": "A0A3Q1MS15_BOVIN", "mass": 128160.0, "length": 1146, "protein_name": "Folliculin interacting protein 1", "gene_name": "FNIP1", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "FNIP1", "gene_names_refseq": "", "protein_names_uniprotkb": "Folliculin interacting protein 1", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008047 enzyme activator activity;GO:0019899 enzyme binding;GO:0051087 protein-folding chaperone binding;GO:0042030 ATPase inhibitor activity", "go_cellular_component": "GO:0005829 cytosol;GO:0005765 lysosomal membrane", "go_biological_process": "GO:1904263 positive regulation of TORC1 signaling;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0031334 positive regulation of protein-containing complex assembly;GO:0030183 B cell differentiation;GO:1905672 negative regulation of lysosome organization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MS15-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MT81-1", "uniprot_id": "A0A3Q1MT81_BOVIN", "mass": 173742.0, "length": 1676, "protein_name": "Soluble scavenger receptor cysteine-rich domain-containing protein SSC5D", "gene_name": "SSC5D", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "SSC5D", "gene_names_refseq": "", "protein_names_uniprotkb": "Soluble scavenger receptor cysteine-rich domain-containing protein SSC5D", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Binds to extracellular matrix proteins. Binds to pathogen-associated molecular patterns (PAMPs) present on the cell walls of Gram-positive and Gram-negative bacteria and fungi, behaving as a pattern recognition receptor (PRR). Induces bacterial and fungal aggregation and subsequent inhibition of PAMP-induced cytokine release. Does not possess intrinsic bactericidal activity. May play a role in the innate defense and homeostasis of certain epithelial surfaces., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 8, "predicted_n_glycosites": 0, "predicted_o_glycosites": 8, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 8, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005044 scavenger receptor activity;GO:0043236 laminin binding;GO:0001968 fibronectin binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0016020 membrane;GO:0031012 extracellular matrix", "go_biological_process": "GO:0042494 detection of bacterial lipoprotein;GO:0006952 defense response;GO:0050829 defense response to Gram-negative bacterium;GO:0050830 defense response to Gram-positive bacterium;GO:0032717 negative regulation of interleukin-8 production", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MT81-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MTW9-1", "uniprot_id": "A0A3Q1MTW9_BOVIN", "mass": 63436.0, "length": 584, "protein_name": "Multidrug and toxin extrusion protein", "gene_name": "SLC47A1", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "SLC47A1", "gene_names_refseq": "", "protein_names_uniprotkb": "Multidrug and toxin extrusion protein", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0042910 xenobiotic transmembrane transporter activity;GO:0015234 thiamine transmembrane transporter activity;GO:0015489 putrescine transmembrane transporter activity;GO:0061459 L-arginine transmembrane transporter activity;GO:0140968 polyspecific organic cation:proton antiporter activity", "go_cellular_component": "GO:0016323 basolateral plasma membrane;GO:0016324 apical plasma membrane;GO:0016020 membrane", "go_biological_process": "GO:0006855 xenobiotic transmembrane transport;GO:0097638 L-arginine import across plasma membrane;GO:1990961 xenobiotic detoxification by transmembrane export across the plasma membrane", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MTW9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MTY6-1", "uniprot_id": "A0A3Q1MTY6_BOVIN", "mass": 269913.0, "length": 2463, "protein_name": "Microtubule associated protein 1B", "gene_name": "MAP1B", "organism": "Bovine", "refseq_name": "microtubule-associated protein 1B", "refseq_ac": "NP_001193048", "gene_names_uniprotkb": "MAP1B", "gene_names_refseq": "MAP1B", "protein_names_uniprotkb": "Microtubule associated protein 1B", "protein_names_refseq": "microtubule-associated protein 1B", "tax_id": 9913, "disease": "", "pathway": " (bta:514739)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, 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"glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003779 actin binding;GO:0008017 microtubule binding", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0005829 cytosol;GO:0005874 microtubule;GO:0005886 plasma membrane;GO:0014069 postsynaptic density", "go_biological_process": "GO:0007409 axonogenesis;GO:0016358 dendrite development;GO:0000226 microtubule cytoskeleton organization;GO:0031114 regulation of microtubule depolymerization;GO:0150052 regulation of postsynapse assembly", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MTY6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MU57-1", "uniprot_id": "A0A3Q1MU57_BOVIN", "mass": 102770.0, "length": 928, "protein_name": "ATP-dependent RNA helicase DDX54", "gene_name": "DDX54", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "DDX54", "gene_names_refseq": "", "protein_names_uniprotkb": "ATP-dependent RNA helicase DDX54; 3.6.4.13; DEAD box protein 54", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.6.4.12;5.6.2.4;3.6.4.13;2.3.2.27;7.2.2.-;2.7.7.7;2.7.7.49;3.6.1.5;3.6.4.6;3.6.4.10;5.6.2.3;3.6.5.-;5.6.2.-;2.7.4.3;3.6.4.-;2.7.11.1;3.1.-.-;4.2.99.18;5.6.1.6;3.6.1.15;7.6.2.1;3.1.3.1;3.9.1.1;5.6.2.5;3.4.24.-;3.6.-.-;3.6.1.-;5.6.1.7;3.1.4.-;3.4.21.53", "go_molecular_function": "GO:0003723 RNA binding;GO:0005102 signaling receptor binding;GO:0005524 ATP binding;GO:0003714 transcription corepressor activity;GO:0016887 ATP hydrolysis activity", "go_cellular_component": "GO:0005730 nucleolus", "go_biological_process": "GO:0006364 rRNA processing;GO:0006396 RNA processing", "synthesized_glycan_count": 0, 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Binding to the IRE element in ferritin results in the repression of its mRNA translation. Binding of the protein to the transferrin receptor mRNA inhibits the degradation of this otherwise rapidly degraded mRNA., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003994 aconitate hydratase activity;GO:0046872 metal ion binding;GO:0051539 4 iron, 4 sulfur cluster binding;GO:0030350 iron-responsive element binding", "go_cellular_component": "GO:0005829 cytosol;GO:0005737 cytoplasm", "go_biological_process": "GO:0030316 osteoclast differentiation;GO:0006879 intracellular iron ion homeostasis;GO:0017148 negative regulation of translation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MUL6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MUP8-1", "uniprot_id": "A0A3Q1MUP8_BOVIN", "mass": 31409.0, "length": 284, "protein_name": "E3 ubiquitin-protein ligase", "gene_name": "LOC100336539", "organism": "Bovine", "refseq_name": "E3 ubiquitin-protein ligase SIAH1-like", "refseq_ac": "XP_059739794", "gene_names_uniprotkb": "LOC100336539; LOC112445131", "gene_names_refseq": "LOC112445131", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase; 2.3.2.27", "protein_names_refseq": "E3 ubiquitin-protein ligase SIAH1-like", "tax_id": 9913, "disease": "", "pathway": " (bta:100336539); (bta:112445131)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, 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region", "go_biological_process": "GO:0007399 nervous system development;GO:0007368 determination of left/right symmetry;GO:0003341 cilium movement;GO:0036158 outer dynein arm assembly;GO:0033146 regulation of intracellular estrogen receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MXH6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1MYS0-1", "uniprot_id": "A0A3Q1MYS0_BOVIN", "mass": 72348.0, "length": 640, "protein_name": "Sodium/hydrogen exchanger", "gene_name": "SLC9A9", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "SLC9A9", "gene_names_refseq": "", "protein_names_uniprotkb": "Sodium/hydrogen exchanger", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0015385 sodium:proton antiporter activity;GO:0015386 potassium:proton antiporter activity", "go_cellular_component": "GO:0005769 early endosome;GO:0005886 plasma membrane;GO:0030670 phagocytic vesicle membrane;GO:0055038 recycling endosome membrane;GO:0032009 early phagosome", "go_biological_process": "GO:0090382 phagosome maturation;GO:0042742 defense response to bacterium;GO:0051453 regulation of intracellular pH", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1MYS0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1N0G2-1", "uniprot_id": "A0A3Q1N0G2_BOVIN", "mass": 71741.0, "length": 639, "protein_name": "Phosphatidylserine lipase ABHD16A", "gene_name": "ABHD16A", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "ABHD16A", "gene_names_refseq": "", "protein_names_uniprotkb": "Phosphatidylserine lipase ABHD16A; 3.1.1.23; Alpha/beta hydrolase domain-containing protein 16A; Monoacylglycerol lipase ABHD16A", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Phosphatidylserine (PS) lipase that mediates the hydrolysis of phosphatidylserine to generate lysophosphatidylserine (LPS). LPS constitutes a class of signaling lipids that regulates immunological and neurological processes. Has no activity towards diacylglycerol, triacylglycerol or lysophosphatidylserine lipase. Also has monoacylglycerol lipase activity, with preference for 1-(9Z,12Z-octadecadienoyl)-glycerol (1-LG) and 2-glyceryl-15-deoxy-Delta(12,14)-prostaglandin J2 (15d-PGJ(2)-G)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004620 phospholipase activity;GO:0047372 monoacylglycerol lipase activity", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "GO:0052651 monoacylglycerol catabolic process;GO:1905344 prostaglandin catabolic process;GO:0006660 phosphatidylserine catabolic process;GO:0006629 lipid metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1N0G2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1N158-1", "uniprot_id": "A0A3Q1N158_BOVIN", "mass": 103022.0, "length": 911, "protein_name": "Kinesin-like protein", "gene_name": "KIF9", "organism": "Bovine", "refseq_name": "kinesin-like protein KIF9 isoform X1", "refseq_ac": "XP_005223111", "gene_names_uniprotkb": "KIF9", "gene_names_refseq": "KIF9", "protein_names_uniprotkb": "Kinesin-like protein", "protein_names_refseq": "kinesin-like protein KIF9 isoform X1", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Essential for normal male fertility and for progressive motility of spermatozoa., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0008017 microtubule binding;GO:0042802 identical protein binding;GO:0003777 microtubule motor activity", "go_cellular_component": "GO:0002102 podosome;GO:0036126 sperm flagellum;GO:0031982 vesicle;GO:0005879 axonemal microtubule;GO:0005874 microtubule", "go_biological_process": "GO:0071801 regulation of podosome assembly;GO:1903008 organelle disassembly;GO:0022617 extracellular matrix disassembly;GO:0007018 microtubule-based movement;GO:1901317 regulation of flagellated sperm motility", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1N158-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1N1B8-1", "uniprot_id": "A0A3Q1N1B8_BOVIN", "mass": 565970.0, "length": 5040, "protein_name": "Ryanodine receptor 1", "gene_name": "RYR1", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "RYR1", "gene_names_refseq": "", "protein_names_uniprotkb": "Ryanodine receptor 1; Skeletal muscle calcium release channel; Skeletal muscle ryanodine receptor; Skeletal muscle-type ryanodine receptor; Type 1 ryanodine receptor", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-2672351); (R-BTA-5578775)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Cytosolic calcium-activated calcium channel that mediates the release of Ca(2+) from the sarcoplasmic reticulum into the cytosol and thereby plays a key role in triggering muscle contraction following depolarization of T-tubules. Repeated very high-level exercise increases the open probability of the channel and leads to Ca(2+) leaking into the cytoplasm. Can also mediate the release of Ca(2+) from intracellular stores in neurons, and may thereby promote prolonged Ca(2+) signaling in the brain. Required for normal embryonic development of muscle fibers and skeletal muscle. Required for normal heart morphogenesis, skin development and ossification during embryogenesis., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005516 calmodulin binding;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0005219 ryanodine-sensitive calcium-release channel activity", "go_cellular_component": "GO:0005790 smooth endoplasmic reticulum;GO:0005938 cell cortex;GO:0042383 sarcolemma;GO:0030018 Z disc;GO:0034704 calcium channel complex", "go_biological_process": "GO:0001666 response to hypoxia;GO:0006874 intracellular calcium ion homeostasis;GO:0006941 striated muscle contraction;GO:0014808 release of sequestered calcium ion into cytosol by sarcoplasmic reticulum;GO:0071313 cellular response to caffeine", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1N1B8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q58CU4-1", "uniprot_id": "ZDH16_BOVIN", "mass": 43614.0, "length": 377, "protein_name": "Palmitoyltransferase ZDHHC16", "gene_name": "ZDHHC16", "organism": "Bovine", "refseq_name": "palmitoyltransferase ZDHHC16", "refseq_ac": "NP_001019653", "gene_names_uniprotkb": "ZDHHC16", "gene_names_refseq": "ZDHHC16", "protein_names_uniprotkb": "Palmitoyltransferase ZDHHC16; 2.3.1.225; DHHC-16; Zinc finger DHHC domain-containing protein 16", "protein_names_refseq": "DHHC-16; palmitoyltransferase ZDHHC16; probable palmitoyltransferase ZDHHC16; zinc finger DHHC domain-containing protein 16; zinc finger DHHC-type containing 16; zinc finger, DHHC domain containing 16", "tax_id": 9913, "disease": "", "pathway": " (bta:506085)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "Palmitoyl acyltransferase that mediates palmitoylation of proteins such as PLN and ZDHHC6 (By similarity). Required during embryonic heart development and cardiac function, possibly by mediating palmitoylation of PLN, thereby affecting PLN phosphorylation and homooligomerization (By similarity). Also required for eye development (By similarity). Palmitoylates ZDHHC6, affecting the quaternary assembly of ZDHHC6, its localization, stability and function (By similarity). May play a role in DNA damage response (By similarity). May be involved in apoptosis regulation (By similarity). Involved in the proliferation of neural stem cells by regulating the FGF/ERK pathway (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q2HJ39;Q58D89", "ec_number_list": "2.3.1.225;6.3.1.2;2.3.1.-", "go_molecular_function": "GO:0019706 protein-cysteine S-palmitoyltransferase activity;GO:0016409 palmitoyltransferase activity", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0005789 endoplasmic reticulum membrane;GO:0016020 membrane", "go_biological_process": "GO:0007507 heart development;GO:0006915 apoptotic process;GO:0006974 DNA damage response;GO:0001654 eye development;GO:0021537 telencephalon development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q58CU4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1N5C0-1", "uniprot_id": "A0A3Q1N5C0_BOVIN", "mass": 62512.0, "length": 554, "protein_name": "Ubiquitin carboxyl-terminal hydrolase", "gene_name": "USP3", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "USP3", "gene_names_refseq": "", "protein_names_uniprotkb": "Ubiquitin carboxyl-terminal hydrolase; 3.4.19.12", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-5689880)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.4.19.12;2.3.1.48", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0042393 histone binding;GO:0004843 cysteine-type deubiquitinase activity;GO:0140936 histone H2B deubiquitinase activity;GO:0140950 histone H2A deubiquitinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0000785 chromatin", "go_biological_process": "GO:0006281 DNA repair;GO:0006508 proteolysis;GO:0016579 protein deubiquitination;GO:0140861 DNA repair-dependent chromatin remodeling", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1N5C0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1N609-1", "uniprot_id": "A0A3Q1N609_BOVIN", "mass": 71819.0, "length": 643, "protein_name": "Amyloid beta precursor like protein 1", "gene_name": "APLP1", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "APLP1", "gene_names_refseq": "", "protein_names_uniprotkb": "Amyloid beta precursor like protein 1; Amyloid beta (A4) precursor-like protein 1; Amyloid-like protein 1", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "May play a role in postsynaptic function. The C-terminal gamma-secretase processed fragment, ALID1, activates transcription activation through APBB1 (Fe65) binding. Couples to JIP signal transduction through C-terminal binding. May interact with cellular G-protein signaling pathways. Can regulate neurite outgrowth through binding to components of the extracellular matrix such as heparin and collagen I., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; The gamma-CTF peptide, C30, is a potent enhancer of neuronal apoptosis., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008201 heparin binding;GO:0042802 identical protein binding;GO:0046914 transition metal ion binding;GO:0031694 alpha-2A adrenergic receptor binding;GO:0031696 alpha-2C adrenergic receptor binding", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0005886 plasma membrane;GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "GO:0006897 endocytosis;GO:0007155 cell adhesion;GO:0007399 nervous system development;GO:0071874 cellular response to norepinephrine stimulus;GO:0006915 apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1N609-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q5BIM9-1", "uniprot_id": "GPHR_BOVIN", "mass": 52952.0, "length": 455, "protein_name": "Golgi pH regulator", "gene_name": "GPHR; GPR89A", "organism": "Bovine", "refseq_name": "Golgi pH regulator", "refseq_ac": "NP_001070438", "gene_names_uniprotkb": "GPHR; GPR89A; GPR89A; GPR89", "gene_names_refseq": "GPR89A; GPR89", "protein_names_uniprotkb": "Golgi pH regulator; Protein GPR89", "protein_names_refseq": "G protein-coupled receptor 89; Golgi pH regulator; protein GPR89", "tax_id": 9913, "disease": "", "pathway": " (bta:767859)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "Voltage-gated channel that enables the transfer of monoatomic anions such as iodide, chloride, bromide and fluoride which may function in counter-ion conductance and participates in Golgi acidification (By similarity). Plays a role in lymphocyte development, probably by acting as a RABL3 effector in hematopoietic cells (By similarity). Essential for maintaining the acidic luminal pH of the Golgi apparatus in neurons, which is important for preserving Golgi structural integrity (By similarity). This integrity supports proper axonal transport and synaptic maintenance in cerebellar inhibitory neurons, including Purkinje and basket cells (By similarity). Additionally, Golgi acidification facilitates the activation of SREBP2, thereby ensuring sufficient cholesterol biosynthesis necessary for normal neuronal morphology and function (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "Q0VCS7", "ec_number_list": "5.6.1.6;1.8.-.-;1.8.5.1", "go_molecular_function": "GO:0008308 voltage-gated monoatomic anion channel activity;GO:0005198 structural molecule activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0032580 Golgi cisterna membrane;GO:0034702 monoatomic ion channel complex;GO:0030660 Golgi-associated vesicle membrane;GO:0016020 membrane", "go_biological_process": "GO:0015031 protein transport;GO:0030217 T cell differentiation;GO:0051452 intracellular pH reduction", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q5BIM9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1N6Y3-1", "uniprot_id": "A0A3Q1N6Y3_BOVIN", "mass": 31976.0, "length": 292, "protein_name": "Sclerostin", "gene_name": "SOST", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "SOST", "gene_names_refseq": "", "protein_names_uniprotkb": "Sclerostin", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-3772470)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008201 heparin binding;GO:0036122 BMP binding;GO:0140297 DNA-binding transcription factor binding;GO:0140678 molecular function inhibitor activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0090090 negative regulation of canonical Wnt signaling pathway;GO:0009612 response to mechanical stimulus;GO:0045893 positive regulation of DNA-templated transcription;GO:0030514 negative regulation of BMP signaling pathway;GO:0016055 Wnt signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1N6Y3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1N7Y5-1", "uniprot_id": "A0A3Q1N7Y5_BOVIN", "mass": 88380.0, "length": 803, "protein_name": "Transferrin receptor protein 2", "gene_name": "TFR2", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "TFR2", "gene_names_refseq": "", "protein_names_uniprotkb": "Transferrin receptor protein 2", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-917977)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Mediates cellular uptake of transferrin-bound iron in a non-iron dependent manner. May be involved in iron metabolism, hepatocyte function and erythrocyte differentiation., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004998 transferrin receptor activity;GO:0039706 co-receptor binding", "go_cellular_component": "GO:0009897 external side of plasma membrane;GO:0031410 cytoplasmic vesicle;GO:1990712 HFE-transferrin receptor complex;GO:0005886 plasma membrane", "go_biological_process": "GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0071281 cellular response to iron ion;GO:0045807 positive regulation of endocytosis;GO:0033572 transferrin transport;GO:0090277 positive regulation of peptide hormone secretion", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1N7Y5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1N8R7-1", "uniprot_id": "A0A3Q1N8R7_BOVIN", "mass": 46802.0, "length": 410, "protein_name": "Thyroid hormone receptor alpha", "gene_name": "THRA", "organism": "Bovine", "refseq_name": "thyroid hormone receptor alpha isoform X2", "refseq_ac": "XP_059734095", "gene_names_uniprotkb": "THRA", "gene_names_refseq": "THRA", "protein_names_uniprotkb": "Thyroid hormone receptor alpha; Nuclear receptor subfamily 1 group A member 1", "protein_names_refseq": "thyroid hormone receptor alpha isoform X2", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-383280); (R-BTA-4090294)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0004879 nuclear receptor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0090575 RNA polymerase II transcription regulator complex", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0030154 cell differentiation;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0048384 retinoic acid receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1N8R7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1N919-1", "uniprot_id": "A0A3Q1N919_BOVIN", "mass": 38402.0, "length": 350, "protein_name": "Proton-coupled zinc antiporter SLC30A8", "gene_name": "SLC30A8", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "SLC30A8", "gene_names_refseq": "", "protein_names_uniprotkb": "Proton-coupled zinc antiporter SLC30A8; Solute carrier family 30 member 8; Zinc transporter 8", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-264876); (R-BTA-435368)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Proton-coupled zinc ion antiporter mediating the entry of zinc into the lumen of pancreatic beta cell secretory granules, thereby regulating insulin secretion., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005385 zinc ion transmembrane transporter activity;GO:0042803 protein homodimerization activity;GO:0046872 metal ion binding;GO:0140826 zinc:proton antiporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0030658 transport vesicle membrane;GO:0030667 secretory granule membrane", "go_biological_process": "GO:0071577 zinc ion transmembrane transport;GO:0010043 response to zinc ion;GO:0009749 response to glucose;GO:0030073 insulin secretion;GO:0006882 intracellular zinc ion homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1N919-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1NAH0-1", "uniprot_id": "A0A3Q1NAH0_BOVIN", "mass": 10446.0, "length": 94, "protein_name": "Methionine-R-sulfoxide reductase B1", "gene_name": "MSRB1", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "MSRB1", "gene_names_refseq": "", "protein_names_uniprotkb": "Methionine-R-sulfoxide reductase B1; 1.8.4.12; 1.8.4.14; Selenoprotein X", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-5676934)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases, methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residue. Acts as a regulator of actin assembly by reducing methionine (R)-sulfoxide mediated by MICALs (MICAL1, MICAL2 or MICAL3) on actin, thereby promoting filament repolymerization. Plays a role in innate immunity by reducing oxidized actin, leading to actin repolymerization in macrophages., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.8.4.12;1.8.4.14", "go_molecular_function": "GO:0033743 peptide-methionine (R)-S-oxide reductase activity;GO:0033745 L-methionine-(R)-S-oxide reductase activity;GO:0003779 actin binding;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0015629 actin cytoskeleton", "go_biological_process": "GO:0045087 innate immune response;GO:0030041 actin filament polymerization;GO:0030091 protein repair", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1NAH0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1NAK7-1", "uniprot_id": "A0A3Q1NAK7_BOVIN", "mass": 58179.0, "length": 549, "protein_name": "SPNS lysolipid transporter 2, sphingosine-1-phosphate", "gene_name": "SPNS2", "organism": "Bovine", "refseq_name": "sphingosine-1-phosphate transporter SPNS2", "refseq_ac": "NP_001193083", "gene_names_uniprotkb": "SPNS2", "gene_names_refseq": "SPNS2", "protein_names_uniprotkb": "SPNS lysolipid transporter 2, sphingosine-1-phosphate", "protein_names_refseq": "sphingolipid transporter 2; sphingosine-1-phosphate transporter SPNS2", "tax_id": 9913, "disease": "", "pathway": " (bta:613889)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0022857 transmembrane transporter activity;GO:0046624 sphingolipid transporter activity", "go_cellular_component": "GO:0016020 membrane", "go_biological_process": "GO:0003376 sphingosine-1-phosphate receptor signaling pathway;GO:0007605 sensory perception of sound;GO:2000404 regulation of T cell migration;GO:0002920 regulation of humoral immune response", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1NAK7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1NCH0-1", "uniprot_id": "A0A3Q1NCH0_BOVIN", "mass": 46962.0, "length": 411, "protein_name": "G1/S-specific cyclin-E1", "gene_name": "CCNE1", "organism": "Bovine", "refseq_name": "G1/S-specific cyclin-E1", "refseq_ac": "NP_001179705", "gene_names_uniprotkb": "CCNE1", "gene_names_refseq": "CCNE1", "protein_names_uniprotkb": "G1/S-specific cyclin-E1", "protein_names_refseq": "G1/S-specific cyclin-E1", "tax_id": 9913, "disease": "", "pathway": " (bta:533526); (R-BTA-1538133); (R-BTA-187577); (R-BTA-2559586); (R-BTA-6804116); (R-BTA-69017); (R-BTA-69200); (R-BTA-69202); (R-BTA-69231); (R-BTA-69563); (R-BTA-8849470); (R-BTA-9706019)", "pathway_count": 12, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Essential for the control of the cell cycle at the G1/S (start) transition., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0019901 protein kinase binding;GO:0016301 kinase activity;GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0097134 cyclin E1-CDK2 complex;GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005815 microtubule organizing center", "go_biological_process": "GO:0051301 cell division;GO:0000082 G1/S transition of mitotic cell cycle;GO:1902462 positive regulation of mesenchymal stem cell proliferation;GO:1900087 positive regulation of G1/S transition of mitotic cell cycle", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1NCH0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1NDQ7-1", "uniprot_id": "A0A3Q1NDQ7_BOVIN", "mass": 73677.0, "length": 655, "protein_name": "Beta-galactosidase", "gene_name": "GLB1", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "GLB1", "gene_names_refseq": "", "protein_names_uniprotkb": "Beta-galactosidase; 3.2.1.23", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-2022857); (R-BTA-2024101); (R-BTA-4085001); (R-BTA-6798695); (R-BTA-9840310)", "pathway_count": 5, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Cleaves beta-linked terminal galactosyl residues from gangliosides, glycoproteins, and glycosaminoglycans., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.1.1.42;2.5.1.18;2.7.1.1;2.7.11.24;5.3.4.1;3.2.1.23;2.4.2.1;5.2.1.8;4.1.2.13;3.6.1.6;3.1.3.16;2.3.2.27;3.1.6.4;3.1.6.14;3.6.4.13;1.1.1.205;2.7.1.11;3.2.1.18;3.4.19.9;3.2.1.-;2.7.11.22;2.7.11.23;2.3.2.26;2.7.10.2;3.5.1.26;2.4.1.25;3.2.1.33;4.2.99.18;5.6.2.4;3.6.4.12;3.4.23.5;1.13.11.34;1.13.11.12;2.4.1.1;1.6.5.5;3.5.4.4;3.2.1.51;3.6.4.6;3.2.1.52;1.16.3.1;1.11.1.27;3.1.1.4;2.3.1.23;1.11.1.6;3.4.18.1;1.6.2.2;3.4.22.1;3.6.4.10;3.4.22.27;3.4.24.35;3.6.5.-;3.1.1.47;5.3.2.1;5.3.3.12;3.2.1.17;3.4.19.1;3.1.6.8;3.5.1.23;3.5.1.-;3.4.22.52;3.2.1.24;3.5.3.1;2.3.3.8;3.4.16.5;3.4.16.-;5.4.2.11;5.4.2.4;3.3.2.6;3.4.11.4;3.4.21.46;2.7.4.6;2.7.13.3;4.1.2.4;5.3.1.9;5.1.3.-;3.6.1.-;4.2.1.24", "go_molecular_function": "GO:0042803 protein homodimerization activity;GO:0004565 beta-galactosidase activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0016020 membrane;GO:0005764 lysosome;GO:0005773 vacuole;GO:0005576 extracellular region", "go_biological_process": "GO:0006689 ganglioside catabolic process;GO:0019388 galactose catabolic process;GO:0042340 keratan sulfate proteoglycan catabolic process;GO:0005975 carbohydrate metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1NDQ7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1NDR1-1", "uniprot_id": "A0A3Q1NDR1_BOVIN", "mass": 84468.0, "length": 770, "protein_name": "Trifunctional enzyme subunit alpha, mitochondrial", "gene_name": "HADHA", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "HADHA", "gene_names_refseq": "", "protein_names_uniprotkb": "Trifunctional enzyme subunit alpha, mitochondrial; 1.1.1.211; 4.2.1.17; Monolysocardiolipin acyltransferase; TP-alpha", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.1.1.35;4.2.1.17;1.1.1.211;1.1.1.62;1.1.1.239;1.1.1.178;1.1.1.53;1.1.1.159;5.3.3.8", "go_molecular_function": "GO:0016509 long-chain (3S)-3-hydroxyacyl-CoA dehydrogenase (NAD+) activity;GO:0070403 NAD+ binding;GO:0004300 enoyl-CoA hydratase activity;GO:0052816 long-chain fatty acyl-CoA hydrolase activity;GO:0003857 (3S)-3-hydroxyacyl-CoA dehydrogenase (NAD+) activity", "go_cellular_component": "GO:0005743 mitochondrial inner membrane;GO:0042645 mitochondrial nucleoid;GO:0016507 mitochondrial fatty acid beta-oxidation multienzyme complex", "go_biological_process": "GO:0006635 fatty acid beta-oxidation;GO:0035965 cardiolipin acyl-chain remodeling", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1NDR1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1NFP6-1", "uniprot_id": "A0A3Q1NFP6_BOVIN", "mass": 6070.0, "length": 54, "protein_name": "Phorbol-12-myristate-13-acetate-induced protein 1", "gene_name": "PMAIP1", "organism": "Bovine", "refseq_name": "phorbol-12-myristate-13-acetate-induced protein 1", "refseq_ac": "XP_002697825", "gene_names_uniprotkb": "PMAIP1", "gene_names_refseq": "PMAIP1", "protein_names_uniprotkb": "Phorbol-12-myristate-13-acetate-induced protein 1", "protein_names_refseq": "phorbol-12-myristate-13-acetate-induced protein 1", "tax_id": 9913, "disease": "", "pathway": " (bta:100296226); (R-BTA-111448); (R-BTA-111453)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005739 mitochondrion;GO:0005829 cytosol", "go_biological_process": "GO:0051607 defense response to virus;GO:0071456 cellular response to hypoxia;GO:0006974 DNA damage response;GO:0042149 cellular response to glucose starvation;GO:0046902 regulation of mitochondrial membrane permeability", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1NFP6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1NG02-1", "uniprot_id": "A0A3Q1NG02_BOVIN", "mass": 51809.0, "length": 462, "protein_name": "Microspherule protein 1", "gene_name": "MCRS1", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "MCRS1", "gene_names_refseq": "", "protein_names_uniprotkb": "Microspherule protein 1; 58 kDa microspherule protein", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (bta:514410)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0002151 G-quadruplex RNA binding;GO:0008266 poly(U) RNA binding;GO:0034046 poly(G) binding", "go_cellular_component": "GO:0000922 spindle pole;GO:0005730 nucleolus;GO:0031011 Ino80 complex;GO:0005764 lysosome;GO:0000776 kinetochore", "go_biological_process": "GO:0060382 regulation of DNA strand elongation;GO:0006281 DNA repair;GO:0006310 DNA recombination;GO:0006338 chromatin remodeling;GO:0006351 DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1NG02-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q58D72-1", "uniprot_id": "ATLA1_BOVIN", "mass": 63534.0, "length": 558, "protein_name": "Atlastin-1", "gene_name": "ATL1", "organism": "Bovine", "refseq_name": "atlastin-1", "refseq_ac": "NP_001029803", "gene_names_uniprotkb": "ATL1", "gene_names_refseq": "ATL1; SPG3A; atlastin", "protein_names_uniprotkb": "Atlastin-1; 3.6.5.-", "protein_names_refseq": "atlastin-1; spastic paraplegia 3A (autosomal dominant)", "tax_id": 9913, "disease": "", "pathway": " (bta:535424)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "Atlastin-1 (ATL1) is a membrane-anchored GTPase that mediates the GTP-dependent fusion of endoplasmic reticulum (ER) membranes, maintaining the continuous ER network. It facilitates the formation of three-way junctions where ER tubules intersect. Two atlastin-1 on neighboring ER tubules bind GTP and form loose homodimers through the GB1/RHD3-type G domains and 3HB regions. Upon GTP hydrolysis, the 3HB regions tighten, pulling the membranes together to drive their fusion. After fusion, the homodimer disassembles upon release of inorganic phosphate (Pi). Subsequently, GDP dissociates, resetting the monomers to a conformation ready for a new fusion cycle. May also regulate more or less directly Golgi biogenesis (By similarity). Indirectly regulates axonal development (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q3ZBC1", "ec_number_list": "3.6.5.2;3.6.5.5;3.6.5.-;3.6.5.3;2.7.11.1;3.6.1.5;3.6.1.15;3.6.5.4", "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0042802 identical protein binding;GO:0046872 metal ion binding;GO:0140523 GTPase-dependent fusogenic activity", "go_cellular_component": "GO:1990674 Golgi cis cisterna membrane;GO:0000139 Golgi membrane;GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0030424 axon", "go_biological_process": "GO:0007409 axonogenesis;GO:0051260 protein homooligomerization;GO:1990809 endoplasmic reticulum tubular network membrane organization;GO:0007029 endoplasmic reticulum organization;GO:0016320 endoplasmic reticulum membrane fusion", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q58D72-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q58DT4-1", "uniprot_id": "P5CR1_BOVIN", "mass": 33454.0, "length": 320, "protein_name": "Pyrroline-5-carboxylate reductase 1, mitochondrial", "gene_name": "PYCR1", "organism": "Bovine", "refseq_name": "pyrroline-5-carboxylate reductase 1, mitochondrial", "refseq_ac": "NP_001014957", "gene_names_uniprotkb": "PYCR1", "gene_names_refseq": "PYCR1", "protein_names_uniprotkb": "Pyrroline-5-carboxylate reductase 1, mitochondrial; 1.5.1.2; P5C reductase 1; P5CR 1", "protein_names_refseq": "P5C reductase 1; P5CR 1; pyrroline-5-carboxylate reductase 1, mitochondrial", "tax_id": 9913, "disease": "", "pathway": " (bta:539606); (R-BTA-8964539)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "Oxidoreductase that catalyzes the last step in proline biosynthesis, which corresponds to the reduction of pyrroline-5-carboxylate to L-proline using NAD(P)H. At physiologic concentrations, has higher specific activity in the presence of NADH. Involved in the cellular response to oxidative stress., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.5.1.2", "go_molecular_function": "GO:0004735 pyrroline-5-carboxylate reductase activity;GO:0042802 identical protein binding", "go_cellular_component": "GO:0005739 mitochondrion;GO:1902792 pyrroline-5-carboxylate reductase complex", "go_biological_process": "GO:0051881 regulation of mitochondrial membrane potential;GO:0034599 cellular response to oxidative stress;GO:0055129 L-proline biosynthetic process;GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q58DT4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q5E9A4-1", "uniprot_id": "RAE1L_BOVIN", "mass": 40967.0, "length": 368, "protein_name": "mRNA export factor", "gene_name": "RAE1", "organism": "Bovine", "refseq_name": "mRNA export factor", "refseq_ac": "NP_001015585", "gene_names_uniprotkb": "RAE1; MRNP41", "gene_names_refseq": "RAE1", "protein_names_uniprotkb": "mRNA export factor; Rae1 protein homolog; mRNA-associated protein mrnp 41", "protein_names_refseq": "RAE1 RNA export 1 homolog; mRNA export factor; mRNA-associated protein mrnp 41; rae1 protein homolog", "tax_id": 9913, "disease": "", "pathway": " (bta:513080); (R-BTA-159227); (R-BTA-159230); (R-BTA-159231); (R-BTA-159236); (R-BTA-1855170); (R-BTA-1855196); (R-BTA-1855229); (R-BTA-191859); (R-BTA-3108214); (R-BTA-3232142); (R-BTA-3301854); (R-BTA-3371453); (R-BTA-4085377); (R-BTA-4551638); (R-BTA-4570464); (R-BTA-4615885)", "pathway_count": 17, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "Plays a role in mitotic bipolar spindle formation. Binds mRNA. May function in nucleocytoplasmic transport and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding;GO:0043130 ubiquitin binding", "go_cellular_component": "GO:0005643 nuclear pore;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0001650 fibrillar center;GO:0097431 mitotic spindle pole", "go_biological_process": "GO:0051301 cell division;GO:0060236 regulation of mitotic spindle organization;GO:0006405 RNA export from nucleus;GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q5E9A4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1NI32-1", "uniprot_id": "A0A3Q1NI32_BOVIN", "mass": 108887.0, "length": 958, "protein_name": "Thyroid hormone receptor associated protein 3", "gene_name": "THRAP3", "organism": "Bovine", "refseq_name": "thyroid hormone receptor-associated protein 3", "refseq_ac": "NP_001192494", "gene_names_uniprotkb": "THRAP3", "gene_names_refseq": "THRAP3", "protein_names_uniprotkb": "Thyroid hormone receptor associated protein 3", "protein_names_refseq": "thyroid hormone receptor-associated protein 3", "tax_id": 9913, "disease": "", "pathway": " (bta:505228)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0003713 transcription coactivator activity;GO:0051219 phosphoprotein binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0046966 nuclear thyroid hormone receptor binding", "go_cellular_component": "GO:0016607 nuclear speck;GO:0016592 mediator complex;GO:0035145 exon-exon junction complex", "go_biological_process": "GO:0048026 positive regulation of mRNA splicing, via spliceosome;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0048255 mRNA stabilization;GO:0007623 circadian rhythm;GO:0000956 nuclear-transcribed mRNA catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1NI32-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q5EAD0-1", "uniprot_id": "BAIP2_BOVIN", "mass": 57566.0, "length": 521, "protein_name": "BAR/IMD domain-containing adapter protein 2", "gene_name": "BAIAP2", "organism": "Bovine", "refseq_name": "BAR/IMD domain-containing adapter protein 2", "refseq_ac": "NP_001017937", "gene_names_uniprotkb": "BAIAP2", "gene_names_refseq": "BAIAP2", "protein_names_uniprotkb": "BAR/IMD domain-containing adapter protein 2; BAI-associated protein 2; BAI1-associated protein 2; Brain-specific angiogenesis inhibitor 1-associated protein 2", "protein_names_refseq": "BAI-associated protein 2; BAI1 associated protein 2; BAR/IMD domain-containing adapter protein 2; brain-specific angiogenesis inhibitor 1-associated protein 2", "tax_id": 9913, "disease": "", "pathway": " (bta:507837); (R-BTA-2029482); (R-BTA-5663213); (R-BTA-9013423)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "Adapter protein that links membrane-bound small G proteins to cytoplasmic effector proteins. Necessary for CDC42-mediated reorganization of the actin cytoskeleton and for RAC1-mediated membrane ruffling. Involved in the regulation of the actin cytoskeleton by WASF family members and the Arp2/3 complex. Plays a role in neurite growth. Acts syngeristically with ENAH to promote filipodia formation. Plays a role in the reorganization of the actin cytoskeleton in response to bacterial infection. Participates in actin bundling when associated with EPS8, promoting filopodial protrusions (By similarity)., [UniProtKB, UniProtKB]; Adapter protein that links membrane-bound small G-proteins to cytoplasmic effector proteins. Necessary for CDC42-mediated reorganization of the actin cytoskeleton and for RAC1-mediated membrane ruffling. Involved in the regulation of the actin cytoskeleton by WASF family members and the Arp2/3 complex. Plays a role in neurite growth. Acts syngeristically with ENAH to promote filipodia formation. Plays a role in the reorganization of the actin cytoskeleton in response to bacterial infection. Participates in actin bundling when associated with EPS8, promoting filopodial protrusions., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 11, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008093 cytoskeletal anchor activity;GO:0070064 proline-rich region binding;GO:0042803 protein homodimerization activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0005856 cytoskeleton;GO:0016020 membrane;GO:0030175 filopodium", "go_biological_process": "GO:0007009 plasma membrane organization;GO:0032956 regulation of actin cytoskeleton organization;GO:0051017 actin filament bundle assembly;GO:0030182 neuron differentiation;GO:0008360 regulation of cell shape", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q5EAD0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1NK97-1", "uniprot_id": "A0A3Q1NK97_BOVIN", "mass": 157516.0, "length": 1375, "protein_name": "Ubiquitin carboxyl-terminal hydrolase 47", "gene_name": "USP47", "organism": "Bovine", "refseq_name": "ubiquitin carboxyl-terminal hydrolase 47", "refseq_ac": "NP_001230219", "gene_names_uniprotkb": "USP47", "gene_names_refseq": "USP47", "protein_names_uniprotkb": "Ubiquitin carboxyl-terminal hydrolase 47; 3.4.19.12; Deubiquitinating enzyme 47; Ubiquitin thioesterase 47; Ubiquitin-specific-processing protease 47", "protein_names_refseq": "ubiquitin carboxyl-terminal hydrolase 47", "tax_id": 9913, "disease": "", "pathway": " (bta:511121); (R-BTA-5689880)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.4.19.12;2.7.7.7;4.2.99.18;4.2.99.-", "go_molecular_function": "GO:0004843 cysteine-type deubiquitinase activity;GO:0071987 WD40-repeat domain binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0019005 SCF ubiquitin ligase complex;GO:0005829 cytosol", "go_biological_process": "GO:0006508 proteolysis;GO:0006284 base-excision repair;GO:0090263 positive regulation of canonical Wnt signaling pathway;GO:0035520 monoubiquitinated protein deubiquitination;GO:0016579 protein deubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1NK97-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1NLJ8-1", "uniprot_id": "A0A3Q1NLJ8_BOVIN", "mass": 173504.0, "length": 1543, "protein_name": "Multidrug resistance-associated protein 1", "gene_name": "ABCC2", "organism": "Bovine", "refseq_name": "ATP-binding cassette sub-family C member 2", "refseq_ac": "XP_024841710", "gene_names_uniprotkb": "ABCC2", "gene_names_refseq": "ABCC2", "protein_names_uniprotkb": "Multidrug resistance-associated protein 1; 7.6.2.2; 7.6.2.3; ATP-binding cassette sub-family C member 1; Glutathione-S-conjugate-translocating ATPase ABCC1; Leukotriene C(4) transporter", "protein_names_refseq": "ATP-binding cassette sub-family C member 2", "tax_id": 9913, "disease": "", "pathway": " (bta:520925); (R-BTA-189483); (R-BTA-382556); (R-BTA-9749641); (R-BTA-9753281); (R-BTA-9754706)", "pathway_count": 6, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "7.6.2.2;7.6.2.3;7.6.2.-;5.6.1.6", "go_molecular_function": "GO:0005524 ATP binding;GO:0008559 ABC-type xenobiotic transporter activity;GO:0016887 ATP hydrolysis activity;GO:0019534 toxin transmembrane transporter activity;GO:0015431 ABC-type glutathione S-conjugate transporter activity", "go_cellular_component": "GO:0009986 cell surface;GO:0016324 apical plasma membrane;GO:0046581 intercellular canaliculus;GO:0031982 vesicle;GO:0005886 plasma membrane", "go_biological_process": "GO:0015721 bile acid and bile salt transport;GO:0006855 xenobiotic transmembrane transport;GO:0042167 heme catabolic process;GO:0046618 xenobiotic export from cell;GO:0071716 leukotriene transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1NLJ8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q6GV17-1", "uniprot_id": "TLR10_BOVIN", "mass": 93826.0, "length": 812, "protein_name": "Toll-like receptor 10", "gene_name": "TLR10", "organism": "Bovine", "refseq_name": "toll-like receptor 10 precursor", "refseq_ac": "NP_001070386", "gene_names_uniprotkb": "TLR10", "gene_names_refseq": "TLR10; TLR1", "protein_names_uniprotkb": "Toll-like receptor 10", "protein_names_refseq": "toll-like receptor 10 precursor", "tax_id": 9913, "disease": "", "pathway": " (bta:539791); (R-BTA-168142)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "16701904;16950576;17719743", "class_list": "", "function": "Participates in the innate immune response to microbial agents. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity)., [UniProtKB]; Prediction and comparison of TLR protein domain architectures for multiple species revealed seven conserved regions of LRR patterning associated with the three genes investigated., [RefSeq, PubMed]; The expression analysis showed similar expression profiles for TLR1 and TLR6, which indicate a co-regulation of these two genes, TLR10 had a different expression profile, pointing toward a stronger functional diversification compared to TLR1 and TLR6., [RefSeq, PubMed]", "predicted_glycosites": 6, "predicted_n_glycosites": 6, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 6, "binding_glycan_count": 0, "secondary_ac_list": "A7YK74", "ec_number_list": "", "go_molecular_function": "GO:0004888 transmembrane signaling receptor activity;GO:0042802 identical protein binding;GO:0071723 lipopeptide binding;GO:0038023 signaling receptor activity;GO:0035663 Toll-like receptor 2 binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane", "go_biological_process": "GO:0071221 cellular response to bacterial lipopeptide;GO:0006954 inflammatory response;GO:0045087 innate immune response;GO:0002224 toll-like receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q6GV17-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3Q1NNG9-1", "uniprot_id": "A0A3Q1NNG9_BOVIN", "mass": 88684.0, "length": 811, "protein_name": "F-BAR domain only protein 2", "gene_name": "FCHO2", "organism": "Bovine", "refseq_name": "F-BAR domain only protein 2", "refseq_ac": "NP_001091588", "gene_names_uniprotkb": "FCHO2", "gene_names_refseq": "FCHO2", "protein_names_uniprotkb": "F-BAR domain only protein 2", "protein_names_refseq": "F-BAR domain only protein 2; FCH domain only 2; FCH domain only protein 2-like", "tax_id": 9913, "disease": "", "pathway": " (bta:540808); (R-BTA-8856825); (R-BTA-8856828)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Functions in an early step of clathrin-mediated endocytosis. Has both a membrane binding/bending activity and the ability to recruit proteins essential to the formation of functional clathrin-coated pits. Has a lipid-binding activity with a preference for membranes enriched in phosphatidylserine and phosphoinositides (Pi(4,5) biphosphate) like the plasma membrane. Its membrane-bending activity might be important for the subsequent action of clathrin and adaptors in the formation of clathrin-coated vesicles. Involved in adaptor protein complex AP-2-dependent endocytosis of the transferrin receptor, it also functions in the AP-2-independent endocytosis of the LDL receptor., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005546 phosphatidylinositol-4,5-bisphosphate binding;GO:0042802 identical protein binding;GO:0001786 phosphatidylserine binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0005905 clathrin-coated pit;GO:0030136 clathrin-coated vesicle;GO:0098793 presynapse", "go_biological_process": "GO:0010324 membrane invagination;GO:0072659 protein localization to plasma membrane;GO:0048268 clathrin coat assembly;GO:0072583 clathrin-dependent endocytosis;GO:0048488 synaptic vesicle endocytosis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3Q1NNG9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3S5ZP50-1", "uniprot_id": "A0A3S5ZP50_BOVIN", "mass": 48500.0, "length": 427, "protein_name": "Interferon regulatory factor 8", "gene_name": "IRF8", "organism": "Bovine", "refseq_name": "interferon regulatory factor 8 isoform X1", "refseq_ac": "XP_005218781", "gene_names_uniprotkb": "IRF8", "gene_names_refseq": "IRF8", "protein_names_uniprotkb": "Interferon regulatory factor 8; Interferon consensus sequence-binding protein", "protein_names_refseq": "interferon regulatory factor 8 isoform X1", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Transcription factor that specifically binds to the upstream regulatory region of type I interferon (IFN) and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)). Can both act as a transcriptional activator or repressor. Plays a negative regulatory role in cells of the immune system. Involved in CD8(+) dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence (5'-TGAnTCA/GAAA-3'), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF8 and activation of genes. Required for the development of plasmacytoid dendritic cells (pDCs), which produce most of the type I IFN in response to viral infection. Positively regulates macroautophagy in dendritic cells. Acts as a transcriptional repressor of osteoclast differentiation factors such as NFATC1 and EEIG1., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003700 DNA-binding transcription factor activity;GO:0000976 transcription cis-regulatory region binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm", "go_biological_process": "GO:0002273 plasmacytoid dendritic cell differentiation;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0002314 germinal center B cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3S5ZP50-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3S5ZP65-1", "uniprot_id": "A0A3S5ZP65_BOVIN", "mass": 74048.0, "length": 687, "protein_name": "RNA methyltransferase", "gene_name": "MEPCE", "organism": "Bovine", "refseq_name": "7SK snRNA methylphosphate capping enzyme", "refseq_ac": "NP_001073752", "gene_names_uniprotkb": "MEPCE", "gene_names_refseq": "BCDIN3; MEPCE", "protein_names_uniprotkb": "RNA methyltransferase; 2.1.1.-", "protein_names_refseq": "7SK snRNA methylphosphate capping enzyme; bin3, bicoid-interacting 3", "tax_id": 9913, "disease": "", "pathway": " (bta:519969)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008171 O-methyltransferase activity;GO:0017069 snRNA binding;GO:0097322 7SK snRNA binding;GO:0008173 RNA methyltransferase activity;GO:1990276 RNA 5'-gamma-phosphate methyltransferase activity", "go_cellular_component": "GO:0120259 7SK snRNP", "go_biological_process": "GO:1904871 positive regulation of protein localization to Cajal body;GO:1905382 positive regulation of snRNA transcription by RNA polymerase II;GO:0001510 RNA methylation;GO:0040031 snRNA modification", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3S5ZP65-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3S5ZPA3-1", "uniprot_id": "A0A3S5ZPA3_BOVIN", "mass": 101518.0, "length": 896, "protein_name": "Short transient receptor potential channel 1", "gene_name": "TRPC1", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "TRPC1", "gene_names_refseq": "", "protein_names_uniprotkb": "Short transient receptor potential channel 1", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-3295583); (R-BTA-5578775); (R-BTA-983695)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.11.1", "go_molecular_function": "GO:0070679 inositol 1,4,5 trisphosphate binding;GO:0005102 signaling receptor binding;GO:0051117 ATPase binding;GO:0015279 store-operated calcium channel activity;GO:0005262 calcium channel activity", "go_cellular_component": "GO:0034703 cation channel complex;GO:0005886 plasma membrane;GO:0043235 receptor complex", "go_biological_process": "GO:0051592 response to calcium ion;GO:0051480 regulation of cytosolic calcium ion concentration;GO:0051281 positive regulation of release of sequestered calcium ion into cytosol;GO:0070588 calcium ion transmembrane transport;GO:0042438 melanin biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3S5ZPA3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3S5ZPB3-1", "uniprot_id": "A0A3S5ZPB3_BOVIN", "mass": 46040.0, "length": 406, "protein_name": "Nuclear receptor subfamily 1 group I member 3", "gene_name": "NR1I3", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "NR1I3", "gene_names_refseq": "", "protein_names_uniprotkb": "Nuclear receptor subfamily 1 group I member 3; Constitutive androstane receptor", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-383280)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Binds and transactivates the retinoic acid response elements that control expression of the retinoic acid receptor beta 2 and alcohol dehydrogenase 3 genes. Transactivates both the phenobarbital responsive element module of the human CYP2B6 gene and the CYP3A4 xenobiotic response element., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0004879 nuclear receptor activity;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0003700 DNA-binding transcription factor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0005856 cytoskeleton;GO:0005737 cytoplasm", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0030154 cell differentiation;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0030522 intracellular receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3S5ZPB3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3S5ZPC4-1", "uniprot_id": "A0A3S5ZPC4_BOVIN", "mass": 32905.0, "length": 287, "protein_name": "Iodotyrosine deiodinase 1", "gene_name": "IYD", "organism": "Bovine", "refseq_name": "iodotyrosine deiodinase 1 isoform X1", "refseq_ac": "XP_024852489", "gene_names_uniprotkb": "IYD", "gene_names_refseq": "IYD", "protein_names_uniprotkb": "Iodotyrosine deiodinase 1; 1.21.1.1; Iodotyrosine dehalogenase 1", "protein_names_refseq": "iodotyrosine deiodinase 1 isoform X1", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-209968)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalyzes the dehalogenation of halotyrosines such as 3-bromo-L-tyrosine, 3-chloro-L-tyrosine, 3-iodo-L-tyrosine and 3,5-diiodo-L-tyrosine. During thyroid hormone biosynthesis, facilitates iodide salvage by catalysing the oxidative NADPH-dependent deiodination of the halogenated by-products of thyroid hormone production, monoiodotyrosine (L-MIT) and diiodotyrosine (L-DIT). The scavanged iodide can then reenter the hormone-producing pathways. Acts more efficiently on 3-iodo-L-tyrosine than 3,5-diiodo-L-tyrosine., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A3Q1M368", "ec_number_list": "1.21.1.1", "go_molecular_function": "GO:0016491 oxidoreductase activity;GO:0010181 FMN binding;GO:0140616 iodotyrosine deiodinase activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0042403 thyroid hormone metabolic process;GO:0006570 tyrosine metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3S5ZPC4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3S5ZPJ8-1", "uniprot_id": "A0A3S5ZPJ8_BOVIN", "mass": 40315.0, "length": 367, "protein_name": "Cathepsin L", "gene_name": "CTSL", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "CTSL", "gene_names_refseq": "", "protein_names_uniprotkb": "Cathepsin L", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008234 cysteine-type peptidase activity;GO:0004197 cysteine-type endopeptidase activity", "go_cellular_component": "GO:0005764 lysosome;GO:0005615 extracellular space", "go_biological_process": "GO:0006508 proteolysis;GO:0051603 proteolysis involved in protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3S5ZPJ8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3S5ZPJ9-1", "uniprot_id": "A0A3S5ZPJ9_BOVIN", "mass": 102799.0, "length": 896, "protein_name": "Beta-mannosidase", "gene_name": "MANBA", "organism": "Bovine", "refseq_name": "beta-mannosidase isoform X1", "refseq_ac": "XP_010804247", "gene_names_uniprotkb": "MANBA", "gene_names_refseq": "MANBA", "protein_names_uniprotkb": "Beta-mannosidase; 3.2.1.25; Lysosomal beta A mannosidase; Mannanase", "protein_names_refseq": "beta-mannosidase isoform X1", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-6798695); (R-BTA-8853383)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Exoglycosidase that cleaves the single beta-linked mannose residue from the non-reducing end of all N-linked glycoprotein oligosaccharides., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.5.1.92;7.6.2.1;3.6.5.2;3.2.1.25;3.4.16.2;3.1.3.5;3.1.3.2;3.1.3.48;2.5.1.18;2.4.1.-;2.4.1.275;2.4.1.22;2.4.1.38;2.4.1.90;3.2.1.20;3.4.23.-", "go_molecular_function": "GO:0004567 beta-mannosidase activity", "go_cellular_component": "GO:0005764 lysosome", "go_biological_process": "GO:0005975 carbohydrate metabolic process;GO:0006516 glycoprotein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3S5ZPJ9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3S5ZPK5-1", "uniprot_id": "A0A3S5ZPK5_BOVIN", "mass": 212729.0, "length": 1948, "protein_name": "WD repeat-containing protein 81", "gene_name": "WDR81", "organism": "Bovine", "refseq_name": "WD repeat-containing protein 81 isoform X1", "refseq_ac": "XP_005220210", "gene_names_uniprotkb": "WDR81", "gene_names_refseq": "WDR81", "protein_names_uniprotkb": "WD repeat-containing protein 81", "protein_names_refseq": "WD repeat-containing protein 81 isoform X1", "tax_id": 9913, "disease": "", "pathway": " (bta:514104)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Functions as a negative regulator of the PI3 kinase/PI3K activity associated with endosomal membranes via BECN1, a core subunit of the PI3K complex. By modifying the phosphatidylinositol 3-phosphate/PtdInsP3 content of endosomal membranes may regulate endosome fusion, recycling, sorting and early to late endosome transport. It is for instance, required for the delivery of cargos like BST2/tetherin from early to late endosome and thereby participates indirectly to their degradation by the lysosome. May also play a role in aggrephagy, the macroautophagic degradation of ubiquitinated protein aggregates. In this process, may regulate the interaction of SQSTM1 with ubiquitinated proteins and also recruit MAP1LC3C. May also be involved in maintenance of normal mitochondrial structure and organization., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0070530 K63-linked polyubiquitin modification-dependent protein binding;GO:0035014 phosphatidylinositol 3-kinase regulator activity;GO:0141039 phosphatidylinositol 3-kinase inhibitor activity", "go_cellular_component": "GO:0000421 autophagosome membrane;GO:0005739 mitochondrion;GO:0005829 cytosol;GO:0005765 lysosomal membrane;GO:0031902 late endosome membrane", "go_biological_process": "GO:0050821 protein stabilization;GO:0045022 early endosome to late endosome transport;GO:0007005 mitochondrion organization;GO:0006511 ubiquitin-dependent protein catabolic process;GO:0035973 aggrephagy", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3S5ZPK5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3S5ZPM1-1", "uniprot_id": "A0A3S5ZPM1_BOVIN", "mass": 34794.0, "length": 330, "protein_name": "Aquaporin-8", "gene_name": "AQP8", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "AQP8", "gene_names_refseq": "", "protein_names_uniprotkb": "Aquaporin-8", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-432047)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0015250 water channel activity;GO:0015265 urea channel activity;GO:0008519 ammonium channel activity;GO:0015264 methylammonium channel activity", "go_cellular_component": "GO:0097708 intracellular vesicle;GO:0005743 mitochondrial inner membrane;GO:0005886 plasma membrane;GO:0016323 basolateral plasma membrane;GO:0030868 smooth endoplasmic reticulum membrane", "go_biological_process": "GO:0071320 cellular response to cAMP;GO:0045540 regulation of cholesterol biosynthetic process;GO:0030183 B cell differentiation;GO:0006833 water transport;GO:1990748 cellular detoxification", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3S5ZPM1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3S5ZPM3-1", "uniprot_id": "A0A3S5ZPM3_BOVIN", "mass": 60780.0, "length": 559, "protein_name": "6-phosphogluconate dehydrogenase, decarboxylating", "gene_name": "PGD", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "PGD", "gene_names_refseq": "", "protein_names_uniprotkb": "6-phosphogluconate dehydrogenase, decarboxylating; 1.1.1.44", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-71336)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.1.1.44", "go_molecular_function": "GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity;GO:0050661 NADP binding", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0009051 pentose-phosphate shunt, oxidative branch;GO:0019521 D-gluconate metabolic process;GO:0006098 pentose-phosphate shunt", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3S5ZPM3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3S5ZPN6-1", "uniprot_id": "A0A3S5ZPN6_BOVIN", "mass": 54013.0, "length": 478, "protein_name": "Scavenger receptor class B member 2", "gene_name": "SCARB2", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "SCARB2", "gene_names_refseq": "", "protein_names_uniprotkb": "Scavenger receptor class B member 2", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-8856825); (R-BTA-8856828)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005044 scavenger receptor activity;GO:0019899 enzyme binding;GO:0042803 protein homodimerization activity;GO:0051087 protein-folding chaperone binding;GO:0015485 cholesterol binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005765 lysosomal membrane;GO:0030666 endocytic vesicle membrane;GO:0043202 lysosomal lumen", "go_biological_process": "GO:0006914 autophagy;GO:0006898 receptor-mediated endocytosis;GO:0006622 protein targeting to lysosome;GO:0015917 aminophospholipid transport;GO:0043470 regulation of carbohydrate catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3S5ZPN6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A3S5ZPU0-1", "uniprot_id": "A0A3S5ZPU0_BOVIN", "mass": 117657.0, "length": 1068, "protein_name": "DNA ligase", "gene_name": "LIG1", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "LIG1", "gene_names_refseq": "", "protein_names_uniprotkb": "DNA ligase; 6.5.1.1", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-110362); (R-BTA-174414); (R-BTA-5358565); (R-BTA-5358606); (R-BTA-5651801); (R-BTA-5685938); (R-BTA-6782210); (R-BTA-69183)", "pathway_count": 8, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "DNA ligase that seals nicks in double-stranded during DNA repair. Also involved in DNA replication and DNA recombination., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.3.1.48;6.5.1.1;5.2.1.8;2.7.7.7;3.4.19.12;5.6.2.4;2.3.2.27;3.1.11.2;3.1.21.-;3.1.-.-;5.6.2.1;3.1.13.-;2.7.7.48;2.7.7.6;5.6.2.3;2.7.11.1;4.2.99.18;4.2.99.-;3.6.4.-", "go_molecular_function": "GO:0003677 DNA binding;GO:0005524 ATP binding;GO:0003910 DNA ligase (ATP) activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm", "go_biological_process": "GO:0071897 DNA biosynthetic process;GO:0006273 lagging strand elongation;GO:0006310 DNA recombination;GO:0051301 cell division;GO:0006284 base-excision repair", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A3S5ZPU0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A452DHX8-1", "uniprot_id": "A0A452DHX8_BOVIN", "mass": 90531.0, "length": 813, "protein_name": "Amine oxidase", "gene_name": "SAO", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "SAO", "gene_names_refseq": "", "protein_names_uniprotkb": "Amine oxidase; 1.4.3.-", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005507 copper ion binding;GO:0008131 primary methylamine oxidase activity;GO:0048038 quinone binding", "go_cellular_component": "GO:0005769 early endosome;GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0005886 plasma membrane", "go_biological_process": "GO:0009308 amine metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A452DHX8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3ZC26-1", "uniprot_id": "SC5AB_BOVIN", "mass": 73957.0, "length": 674, "protein_name": "Sodium/myo-inositol cotransporter 2", "gene_name": "SLC5A11", "organism": "Bovine", "refseq_name": "sodium/myo-inositol cotransporter 2", "refseq_ac": "NP_001029832", "gene_names_uniprotkb": "SLC5A11; SMIT2", "gene_names_refseq": "SLC5A11; SMIT2", "protein_names_uniprotkb": "Sodium/myo-inositol cotransporter 2; Na(+)/myo-inositol cotransporter 2; SMIT2; Sodium/myo-inositol transporter 2; Solute carrier family 5 member 11", "protein_names_refseq": "Na(+)/myo-inositol cotransporter 2; na+/myo-inositol cotransporter 2; sodium/myo-inositol cotransporter 2; sodium/myo-inositol transporter 2; solute carrier family 5 (sodium/glucose cotransporter), member 11", "tax_id": 9913, "disease": "", "pathway": " (bta:539084); (R-BTA-429593)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Involved in the sodium-dependent cotransport of myo-inositol (MI) with a Na(+):MI stoichiometry of 2:1. Exclusively responsible for apical MI transport and absorption in intestine. Can also transport D-chiro-inositol (DCI) but not L-fucose. Exhibits stereospecific cotransport of both D-glucose and D-xylose. May induce apoptosis through the TNF, PDCD1 pathway. May play a role in the regulation of MI concentration in serum, involving reabsorption in at least the proximal tubule of the kidney., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0015293 symporter activity;GO:0005365 myo-inositol transmembrane transporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016324 apical plasma membrane", "go_biological_process": "GO:0006915 apoptotic process;GO:0006814 sodium ion transport;GO:0015798 myo-inositol transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q3ZC26-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3T100-1", "uniprot_id": "MGST3_BOVIN", "mass": 16884.0, "length": 152, "protein_name": "Glutathione S-transferase 3, mitochondrial", "gene_name": "MGST3", "organism": "Bovine", "refseq_name": "glutathione S-transferase 3, mitochondrial", "refseq_ac": "NP_001030218", "gene_names_uniprotkb": "MGST3", "gene_names_refseq": "MGST3", "protein_names_uniprotkb": "Glutathione S-transferase 3, mitochondrial; 1.11.1.-; 2.5.1.-; 4.4.1.20; Glutathione peroxidase MGST3; LTC4 synthase MGST3", "protein_names_refseq": "LTC4 synthase MGST3; glutathione S-transferase 3, mitochondrial; glutathione peroxidase MGST3; microsomal GST-3; microsomal GST-III; microsomal glutathione S-transferase III", "tax_id": 9913, "disease": "", "pathway": " (bta:507346); (R-BTA-156590); (R-BTA-5423646)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Displays both glutathione S-transferase and glutathione peroxidase activities toward oxyeicosanoids. Catalyzes the Michael addition reaction of reduced glutathione (GSH) to electrophilic eicosanoids to form GSH adducts, as part of detoxification or metabolic shunt processes. Mediates GSH conjugation to leukotriene A4 to form the sulfidopeptide leukotriene C4. Metabolizes cyclopentenone prostanoids, specifically mediates GSH addition at C9 within the cyclopentenone ring of 15-deoxy-Delta12,14-prostaglandin J2 (15dPGJ2) to form 15dPGJ2-glutathione. L-cysteine cannot substitute for GSH. Catalyzes the reduction of eicosanoid peroxides to yield eicosanoid hydroxides., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "4.4.1.20;2.5.1.-;2.5.1.18;1.11.1.12;1.11.1.9;1.11.1.-;5.3.99.3", "go_molecular_function": "GO:0004364 glutathione transferase activity;GO:0004464 leukotriene-C4 synthase activity;GO:0042802 identical protein binding;GO:0004602 glutathione peroxidase activity", "go_cellular_component": "GO:0005635 nuclear envelope;GO:0005741 mitochondrial outer membrane;GO:0005783 endoplasmic reticulum", "go_biological_process": "GO:0019370 leukotriene biosynthetic process;GO:0019369 arachidonate metabolic process;GO:0006692 prostanoid metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q3T100-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A452DIK7-1", "uniprot_id": "A0A452DIK7_BOVIN", "mass": 50455.0, "length": 451, "protein_name": "Tubulin alpha chain", "gene_name": "TUBA1B", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "TUBA1B", "gene_names_refseq": "", "protein_names_uniprotkb": "Tubulin alpha chain", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.6.5.2;3.6.5.5;3.6.5.-;3.6.5.3;2.7.11.1;3.6.1.5;3.6.1.15;3.6.5.4", "go_molecular_function": "GO:0003924 GTPase activity;GO:0005200 structural constituent of cytoskeleton;GO:0005525 GTP binding;GO:0031625 ubiquitin protein ligase binding;GO:0003725 double-stranded RNA binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005874 microtubule;GO:0005929 cilium;GO:0005881 cytoplasmic microtubule", "go_biological_process": "GO:0000278 mitotic cell cycle;GO:0000226 microtubule cytoskeleton organization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A0A452DIK7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3ZC13-1", "uniprot_id": "AP2M1_BOVIN", "mass": 49655.0, "length": 435, "protein_name": "AP-2 complex subunit mu", "gene_name": "AP2M1", "organism": "Bovine", "refseq_name": "AP-2 complex subunit mu", "refseq_ac": "NP_001029695", "gene_names_uniprotkb": "AP2M1", "gene_names_refseq": "AP2M1", "protein_names_uniprotkb": "AP-2 complex subunit mu; AP-2 mu chain; Adaptor protein complex AP-2 subunit mu; Adaptor-related protein complex 2 subunit mu; Clathrin assembly protein complex 2 mu medium chain; Clathrin coat assembly protein AP50; Clathrin coat-associated protein AP50; HA2 50 kDa subunit; Mu2-adaptin; Plasma membrane adaptor AP-2 50 kDa protein", "protein_names_refseq": "AP-2 complex subunit mu; AP-2 mu chain; HA2 50 kDa subunit; adapter-related protein complex 2 mu subunit; adapter-related protein complex 2 subunit mu; adaptor protein complex AP-2 subunit mu; adaptor related protein complex 2 mu 1 subunit; adaptor-related protein complex 2 subunit mu; clathrin assembly protein complex 2 medium chain; clathrin assembly protein complex 2 mu medium chain; clathrin coat assembly protein AP50; clathrin coat-associated protein AP50; mu2-adaptin; plasma membrane adaptor AP-2 50 kDa protein", "tax_id": 9913, "disease": "", "pathway": " (bta:517446); (R-BTA-177504); (R-BTA-190873); (R-BTA-196025); (R-BTA-2132295); (R-BTA-416993); (R-BTA-437239); (R-BTA-5099900); (R-BTA-5140745); (R-BTA-8856825); (R-BTA-8856828); (R-BTA-8866427); (R-BTA-8964038)", "pathway_count": 13, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but is itself unable to bind directly to membrane components. Clathrin-associated adaptor protein (AP) complexes which can bind directly to both the clathrin lattice and to the lipid and protein components of membranes are considered to be the major clathrin adaptors contributing the CCV formation. AP-2 also serves as a cargo receptor to selectively sort the membrane proteins involved in receptor-mediated endocytosis. AP-2 seems to play a role in the recycling of synaptic vesicle membranes from the presynaptic surface. AP-2 recognizes Y-X-X-[FILMV] (Y-X-X-Phi) and [ED]-X-X-X-L-[LI] endocytosis signal motifs within the cytosolic tails of transmembrane cargo molecules., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008289 lipid binding;GO:0035615 clathrin adaptor activity;GO:0044325 transmembrane transporter binding;GO:0005048 signal sequence binding;GO:0097718 disordered domain specific binding", "go_cellular_component": "GO:0005829 cytosol;GO:0030122 AP-2 adaptor complex;GO:0008021 synaptic vesicle;GO:0030121 AP-1 adaptor complex;GO:0098978 glutamatergic synapse", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0031623 receptor internalization;GO:0072583 clathrin-dependent endocytosis;GO:0099003 vesicle-mediated transport in synapse;GO:0006896 Golgi to vacuole transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q3ZC13-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3T145-1", "uniprot_id": "MDHC_BOVIN", "mass": 36438.0, "length": 334, "protein_name": "Malate dehydrogenase, cytoplasmic", "gene_name": "MDH1", "organism": "Bovine", "refseq_name": "malate dehydrogenase, cytoplasmic isoform MDH1", "refseq_ac": "NP_001029800", "gene_names_uniprotkb": "MDH1", "gene_names_refseq": "KAR; MDH1", "protein_names_uniprotkb": "Malate dehydrogenase, cytoplasmic; 1.1.1.37; Aromatic alpha-keto acid reductase; Cytosolic malate dehydrogenase; KAR", "protein_names_refseq": "aromatic alpha-keto acid reductase; cytosolic malate dehydrogenase; malate dehydrogenase 1, NAD (soluble); malate dehydrogenase, cytoplasmic isoform MDH1; malate dehydrogenase, cytoplasmic; malate dehydrogenase, peroxisomal", "tax_id": 9913, "disease": "", "pathway": " (bta:535182); (R-BTA-9856872)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalyzes the reduction of aromatic alpha-keto acids in the presence of NADH. Plays essential roles in the malate-aspartate shuttle and the tricarboxylic acid cycle, important in mitochondrial NADH supply for oxidative phosphorylation. Catalyzes the reduction of 2-oxoglutarate to 2-hydroxyglutarate, leading to elevated reactive oxygen species (ROS)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; This gene encodes an enzyme that catalyzes the NAD/NADH-dependent, reversible oxidation of malate to oxaloacetate in many metabolic pathways, including the citric acid cycle. Two main isozymes are known to exist in eukaryotic cells: one is found in the mitochondrial matrix and the other in the cytoplasm. This gene encodes the cytosolic isozyme, which plays a key role in the malate-aspartate shuttle that allows malate to pass through the mitochondrial membrane to be transformed into oxaloacetate for further cellular processes. Alternatively spliced transcript variants have been found for this gene. A recent study showed that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is localized in the peroxisomes. [provided by RefSeq, Feb 2016]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.1.1.37;1.1.1.399;1.1.1.95", "go_molecular_function": "GO:0030060 L-malate dehydrogenase (NAD+) activity;GO:0047995 (2R)-hydroxyphenylpyruvate reductase [NAD(P)H] activity;GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0016615 malate dehydrogenase activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0006739 NADP+ metabolic process;GO:0006099 tricarboxylic acid cycle;GO:0006107 oxaloacetate metabolic process;GO:0019674 NAD+ metabolic process;GO:0006108 malate metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q3T145-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q5E9A3-1", "uniprot_id": "PCBP1_BOVIN", "mass": 37498.0, "length": 356, "protein_name": "Poly(rC)-binding protein 1", "gene_name": "PCBP1", "organism": "Bovine", "refseq_name": "poly(rC)-binding protein 1", "refseq_ac": "NP_001015565", "gene_names_uniprotkb": "PCBP1", "gene_names_refseq": "PCBP1; hnRNP-E1", "protein_names_uniprotkb": "Poly(rC)-binding protein 1; Alpha-CP1", "protein_names_refseq": "alpha-CP1; poly(rC)-binding protein 1", "tax_id": 9913, "disease": "", "pathway": " (bta:509917); (R-BTA-72163); (R-BTA-72203); (R-BTA-9770562)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "Single-stranded nucleic acid binding protein that binds preferentially to oligo dC (By similarity). Together with PCBP2, required for erythropoiesis, possibly by regulating mRNA splicing (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding;GO:0003729 mRNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003730 mRNA 3'-UTR binding;GO:0003697 single-stranded DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0016607 nuclear speck", "go_biological_process": "GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0039694 viral RNA genome replication", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q5E9A3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3ZC10-1", "uniprot_id": "SMD1_BOVIN", "mass": 13282.0, "length": 119, "protein_name": "Small nuclear ribonucleoprotein Sm D1", "gene_name": "SNRPD1", "organism": "Bovine", "refseq_name": "small nuclear ribonucleoprotein Sm D1", "refseq_ac": "NP_001030237", "gene_names_uniprotkb": "SNRPD1", "gene_names_refseq": "SNRPD1", "protein_names_uniprotkb": "Small nuclear ribonucleoprotein Sm D1; Sm-D1; snRNP core protein D1", "protein_names_refseq": "sm-D1; small nuclear ribonucleoprotein D1 polypeptide 16kDa; small nuclear ribonucleoprotein Sm D1; snRNP core protein D1", "tax_id": 9913, "disease": "", "pathway": " (bta:508788); (R-BTA-191859); (R-BTA-72163); (R-BTA-72165); (R-BTA-9770562); (R-BTA-9943411)", "pathway_count": 6, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs. May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through non-specific electrostatic contacts with RNA., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding", "go_cellular_component": "GO:0005685 U1 snRNP;GO:0005634 nucleus;GO:0005829 cytosol;GO:0034709 methylosome;GO:0071013 catalytic step 2 spliceosome", "go_biological_process": "GO:0000387 spliceosomal snRNP assembly;GO:0000398 mRNA splicing, via spliceosome", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q3ZC10-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3T0Z8-1", "uniprot_id": "RUXF_BOVIN", "mass": 9725.0, "length": 86, "protein_name": "Small nuclear ribonucleoprotein F", "gene_name": "SNRPF", "organism": "Bovine", "refseq_name": "small nuclear ribonucleoprotein F", "refseq_ac": "NP_001181956", "gene_names_uniprotkb": "SNRPF", "gene_names_refseq": "SNRPF; Sm-F; SmF; snRNP-F", "protein_names_uniprotkb": "Small nuclear ribonucleoprotein F; Sm protein F; Sm-F; SmF; snRNP-F", "protein_names_refseq": "sm protein F; small nuclear ribonucleoprotein F", "tax_id": 9913, "disease": "", "pathway": " (bta:615240); (R-BTA-111367); (R-BTA-191859); (R-BTA-72163); (R-BTA-72165); (R-BTA-73856); (R-BTA-77588); (R-BTA-9770562); (R-BTA-9943411)", "pathway_count": 9, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Plays a role in pre-mRNA splicing as core component of the SMN-Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs. As part of the U7 snRNP it is involved in histone 3'-end processing., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding", "go_cellular_component": "GO:0005685 U1 snRNP;GO:0005634 nucleus;GO:0005829 cytosol;GO:0034709 methylosome;GO:0071013 catalytic step 2 spliceosome", "go_biological_process": "GO:0000387 spliceosomal snRNP assembly;GO:0000398 mRNA splicing, via spliceosome", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q3T0Z8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q5BIN5-1", "uniprot_id": "PIN1_BOVIN", "mass": 18273.0, "length": 163, "protein_name": "Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1", "gene_name": "PIN1", "organism": "Bovine", "refseq_name": "peptidyl-prolyl cis-trans isomerase NIMA-interacting 1", "refseq_ac": "NP_001029804", "gene_names_uniprotkb": "PIN1", "gene_names_refseq": "PIN1", "protein_names_uniprotkb": "Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1; 5.2.1.8; PPIase Pin1; Peptidyl-prolyl cis-trans isomerase Pin1; Rotamase Pin1", "protein_names_refseq": "PPIase Pin1; peptidyl-prolyl cis-trans isomerase NIMA-interacting 1; peptidyl-prolyl cis-trans isomerase Pin1; protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1; protein (peptidylprolyl cis/trans isomerase) NIMA-interacting 1; rotamase Pin1", "tax_id": 9913, "disease": "", "pathway": " (bta:535470); (R-BTA-5668599); (R-BTA-6804756); (R-BTA-6811555); (R-BTA-936440)", "pathway_count": 5, "publication_count": 2, "publication_id_list": "16305752;16621422", "class_list": "", "function": "Peptidyl-prolyl cis/trans isomerase (PPIase) that binds to and isomerizes specific phosphorylated Ser/Thr-Pro (pSer/Thr-Pro) motifs. By inducing conformational changes in a subset of phosphorylated proteins, acts as a molecular switch in multiple cellular processes. Displays a preference for acidic residues located N-terminally to the proline bond to be isomerized. Regulates mitosis presumably by interacting with NIMA and attenuating its mitosis-promoting activity. Down-regulates kinase activity of BTK. Can transactivate multiple oncogenes and induce centrosome amplification, chromosome instability and cell transformation. Required for the efficient dephosphorylation and recycling of RAF1 after mitogen activation. Binds and targets PML and BCL6 for degradation in a phosphorylation-dependent manner. Acts as a regulator of JNK cascade by binding to phosphorylated FBXW7, disrupting FBXW7 dimerization and promoting FBXW7 autoubiquitination and degradation: degradation of FBXW7 leads to subsequent stabilization of JUN. May facilitate the ubiquitination and proteasomal degradation of RBBP8/CtIP through CUL3/KLHL15 E3 ubiquitin-protein ligase complex, hence favors DNA double-strand repair through error-prone non-homologous end joining (NHEJ) over error-free, RBBP8-mediated homologous recombination (HR). Upon IL33-induced lung inflammation, catalyzes cis-trans isomerization of phosphorylated IRAK3/IRAK-M, inducing IRAK3 stabilization, nuclear translocation and expression of pro-inflammatory genes in dendritic cells. Catalyzes cis-trans isomerization of phosphorylated phosphoglycerate kinase PGK1 under hypoxic conditions to promote its binding to the TOM complex and targeting to the mitochondrion. Acts as a negative regulator of adipocyte browning by binding to phosphorylated PRDM16, targeting PRDM16 for degradation (By similarity)., [UniProtKB, UniProtKB]; The data provide the first evidence that Pin 1 expression in the granulosa cells but not the theca cells changes during follicular development, and that FSH stimulate the expression of the Pin 1 gene., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "5.2.1.8;2.7.11.1;2.7.1.149;2.7.11.13", "go_molecular_function": "GO:0051219 phosphoprotein binding;GO:0008013 beta-catenin binding;GO:0003755 peptidyl-prolyl cis-trans isomerase activity;GO:0016859 cis-trans isomerase activity;GO:0031434 mitogen-activated protein kinase kinase binding", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0016607 nuclear speck", "go_biological_process": "GO:0042127 regulation of cell population proliferation;GO:0001666 response to hypoxia;GO:1902430 negative regulation of amyloid-beta formation;GO:0050821 protein stabilization;GO:0031647 regulation of protein stability", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q5BIN5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3T0N1-1", "uniprot_id": "MB12A_BOVIN", "mass": 28906.0, "length": 273, "protein_name": "Multivesicular body subunit 12A", "gene_name": "MVB12A", "organism": "Bovine", "refseq_name": "multivesicular body subunit 12A", "refseq_ac": "NP_001029455", "gene_names_uniprotkb": "MVB12A; FAM125A", "gene_names_refseq": "FAM125A; MVB12A", "protein_names_uniprotkb": "Multivesicular body subunit 12A; ESCRT-I complex subunit MVB12A; Protein FAM125A", "protein_names_refseq": "ESCRT-I complex subunit MVB12A; family with sequence similarity 125, member A; multivesicular body subunit 12A", "tax_id": 9913, "disease": "", "pathway": " (bta:507199); (R-BTA-917729)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in the ligand-mediated internalization and down-regulation of EGF receptor (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 7, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0017124 SH3 domain binding;GO:0008289 lipid binding;GO:0043130 ubiquitin binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005813 centrosome;GO:0005829 cytosol;GO:0031902 late endosome membrane;GO:0000813 ESCRT I complex", "go_biological_process": "GO:0015031 protein transport;GO:0032801 receptor catabolic process;GO:0042058 regulation of epidermal growth factor receptor signaling pathway;GO:0046755 viral budding;GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q3T0N1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3ZC75-1", "uniprot_id": "AT5G3_BOVIN", "mass": 14693.0, "length": 141, "protein_name": "ATP synthase F(0) complex subunit C3, mitochondrial", "gene_name": "ATP5MC3", "organism": "Bovine", "refseq_name": "ATP synthase F(0) complex subunit C3, mitochondrial precursor", "refseq_ac": "NP_001029864", "gene_names_uniprotkb": "ATP5MC3; ATP5G3", "gene_names_refseq": "ATP5G3; ATP5MC3", "protein_names_uniprotkb": "ATP synthase F(0) complex subunit C3, mitochondrial; ATP synthase lipid-binding protein; ATP synthase membrane subunit c locus 3; ATP synthase proteolipid P3; ATPase protein 9; ATPase subunit c", "protein_names_refseq": "ATP synthase F(0) complex subunit C3, mitochondrial precursor; ATP synthase F(0) complex subunit C3, mitochondrial; ATP synthase lipid-binding protein, mitochondrial; ATP synthase proteolipid P3; ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C3 (subunit 9); ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c (subunit 9); ATP synthase, H+ transporting, mitochondrial Fo complex subunit C3 (subunit 9); ATPase protein 9; ATPase subunit c", "tax_id": 9913, "disease": "", "pathway": " (bta:540176)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. A homomeric c-ring of probably 10 subunits is part of the complex rotary element., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008289 lipid binding;GO:0015078 proton transmembrane transporter activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0031966 mitochondrial membrane;GO:0045259 proton-transporting ATP synthase complex;GO:0033177 proton-transporting two-sector ATPase complex, proton-transporting domain", "go_biological_process": "GO:0015986 proton motive force-driven ATP synthesis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q3ZC75-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q5E9C3-1", "uniprot_id": "SSNA1_BOVIN", "mass": 13599.0, "length": 119, "protein_name": "Microtubule nucleation factor SSNA1", "gene_name": "SSNA1", "organism": "Bovine", "refseq_name": "microtubule nucleation factor SSNA1", "refseq_ac": "NP_001015539", "gene_names_uniprotkb": "SSNA1", "gene_names_refseq": "N14; NA14; SSNA1", "protein_names_uniprotkb": "Microtubule nucleation factor SSNA1; Sjoegren syndrome nuclear autoantigen 1 homolog", "protein_names_refseq": "Sjogren's syndrome nuclear autoantigen 1; microtubule nucleation factor SSNA1; nuclear autoantigen of 14 kDa; sjoegren syndrome nuclear autoantigen 1 homolog", "tax_id": 9913, "disease": "", "pathway": " (bta:507840); (R-BTA-2565942); (R-BTA-380259); (R-BTA-380270); (R-BTA-380284); (R-BTA-380320); (R-BTA-5620912); (R-BTA-8854518)", "pathway_count": 8, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "Microtubule-binding protein which stabilizes dynamic microtubules by slowing growth and shrinkage at both plus and minus ends and serves as a sensor of microtubule damage, protecting microtubules from the microtubule-severing enzyme SPAST (By similarity). Induces microtubule branching which is mediated by the formation of long SSNA1 fibrils which guide microtubule protofilaments to split apart from the mother microtubule and form daughter microtubules (By similarity). Plays a role in axon outgrowth and branching (By similarity). Required for cell division (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q2NL12", "ec_number_list": "", "go_molecular_function": "GO:0008017 microtubule binding;GO:0042802 identical protein binding", "go_cellular_component": "GO:0099512 supramolecular fiber;GO:0005634 nucleus;GO:0005813 centrosome;GO:0030424 axon;GO:0005814 centriole", "go_biological_process": "GO:0007409 axonogenesis;GO:0051301 cell division;GO:0007020 microtubule nucleation;GO:0000226 microtubule cytoskeleton organization;GO:0048675 axon extension", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q5E9C3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q8MJG1-1", "uniprot_id": "PSIP1_BOVIN", "mass": 60099.0, "length": 530, "protein_name": "PC4 and SFRS1-interacting protein", "gene_name": "PSIP1", "organism": "Bovine", "refseq_name": "PC4 and SFRS1-interacting protein", "refseq_ac": "NP_001193405", "gene_names_uniprotkb": "PSIP1; LEDGF", "gene_names_refseq": "PSIP1", "protein_names_uniprotkb": "PC4 and SFRS1-interacting protein; Lens epithelium-derived growth factor", "protein_names_refseq": "PC4 and SFRS1-interacting protein; lens epithelium-derived growth factor", "tax_id": 9913, "disease": "", "pathway": " (bta:282011); (R-BTA-9772755)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Transcriptional coactivator involved in neuroepithelial stem cell differentiation and neurogenesis. Involved in particular in lens epithelial cell gene regulation and stress responses. May play an important role in lens epithelial to fiber cell terminal differentiation. May play a protective role during stress-induced apoptosis (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 20, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A7E383;Q0VCL7", "ec_number_list": "", "go_molecular_function": "GO:0003682 chromatin binding;GO:0003713 transcription coactivator activity;GO:0097100 supercoiled DNA binding;GO:0140297 DNA-binding transcription factor binding;GO:0003677 DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0000791 euchromatin;GO:0000792 heterochromatin;GO:0005654 nucleoplasm", "go_biological_process": "GO:0006338 chromatin remodeling;GO:0006351 DNA-templated transcription;GO:0006979 response to oxidative stress;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0009408 response to heat", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q8MJG1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q5E9T9-1", "uniprot_id": "RTCB_BOVIN", "mass": 55199.0, "length": 505, "protein_name": "RNA-splicing ligase RTCB", "gene_name": "RTCB", "organism": "Bovine", "refseq_name": "RNA-splicing ligase RTCB", "refseq_ac": "NP_001015631", "gene_names_uniprotkb": "RTCB", "gene_names_refseq": "C22orf28; C5H22orf28; HSPC117; RTCB", "protein_names_uniprotkb": "RNA-splicing ligase RTCB; 3'-phosphate/5'-hydroxy nucleic acid ligase; 6.5.1.8; RNA 2',3'-cyclic phosphate and 5'-OH ligase", "protein_names_refseq": "3'-phosphate/5'-hydroxy nucleic acid ligase; RNA-splicing ligase RTCB; RNA-splicing ligase RtcB homolog; tRNA-splicing ligase RtcB homolog", "tax_id": 9913, "disease": "", "pathway": " (bta:525106)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "3'-5' RNA ligase, catalytic subunit of the tRNA-splicing ligase complex (tRNA-LC), which is involved in the enzyme-dependent maturation of intron-containing pre-tRNAs. Functions downstream of the tRNA-splicing endonuclease that removes introns, ligating the two generated halves via phosphodiester bond formation. The ligation reaction, which requires guanosine triphosphate (GTP) and Mn(2+), proceeds through three metal-dependent steps. The first step requires ZBTB8OS/Archease and involves the guanylylation of RTCB at its active site histidine, forming a covalent GMP-histidine intermediate. Before the second step, RTCB also hydrolyzes the 2',3'-cyclic phosphate (cP) at the 3' end of the 5' tRNA exon, typically generated by the tRNA-splicing endonuclease, producing a 3' phosphate. The covalently bound GMP is then transferred to this 3' phosphate to form an RNA(3')-P-P-(5')G intermediate. In the final step, the 5'-OH of the 3' exon attacks the activated 3' end of the 5' exon, forming a 3'-5' phosphodiester bond and releasing GMP. RTCB also functions in non-canonical, spliceosome-independent, cytoplasmic splicing of XBP1 mRNAs during the unfolded protein response (UPR). Upon endoplasmic reticulum (ER) stress, the endoribonuclease IRE1/ERN1 excises a short intron, generating free exon ends that are aligned by RNA-intrinsic, zipper-like stem-loop structures. These exon ends are then recognized and ligated by RTCB. This splicing event yields the active XBP1s transcription factor, which induces genes required to resolve protein folding defects in the endoplasmic reticulum., [UniProtKB, UniProtKB]; Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.7.-;6.5.1.8", "go_molecular_function": "GO:0005525 GTP binding;GO:0046872 metal ion binding;GO:0170057 RNA ligase (GTP) activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005635 nuclear envelope;GO:0005737 cytoplasm;GO:0005789 endoplasmic reticulum membrane;GO:0072669 tRNA-splicing ligase complex", "go_biological_process": "GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q5E9T9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q5E9D3-1", "uniprot_id": "MIC19_BOVIN", "mass": 26100.0, "length": 227, "protein_name": "MICOS complex subunit MIC19", "gene_name": "CHCHD3", "organism": "Bovine", "refseq_name": "MICOS complex subunit MIC19", "refseq_ac": "NP_001030552", "gene_names_uniprotkb": "CHCHD3; MIC19", "gene_names_refseq": "CHCHD3", "protein_names_uniprotkb": "MICOS complex subunit MIC19; Coiled-coil-helix-coiled-coil-helix domain-containing protein 3", "protein_names_refseq": "MICOS complex subunit MIC19; coiled-coil-helix-coiled-coil-helix domain-containing protein 3, mitochondrial", "tax_id": 9913, "disease": "", "pathway": " (bta:616477)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Has also been shown to function as a transcription factor which binds to the BAG1 promoter and represses BAG1 transcription. Plays an important role in the maintenance of the MICOS complex stability and the mitochondrial cristae morphology., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q3T0L4", "ec_number_list": "", "go_molecular_function": "GO:0060090 molecular adaptor activity;GO:0019902 phosphatase binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005743 mitochondrial inner membrane;GO:0061617 MICOS complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0007007 inner mitochondrial membrane organization;GO:0008053 mitochondrial fusion;GO:0042407 cristae formation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q5E9D3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q5E9K8-1", "uniprot_id": "RETR1_BOVIN", "mass": 53680.0, "length": 493, "protein_name": "Reticulophagy regulator 1", "gene_name": "RETREG1", "organism": "Bovine", "refseq_name": "reticulophagy regulator 1", "refseq_ac": "NP_001015672", "gene_names_uniprotkb": "RETREG1; FAM134B", "gene_names_refseq": "FAM134B; RETREG1", "protein_names_uniprotkb": "Reticulophagy regulator 1; Reticulophagy receptor 1", "protein_names_refseq": "family with sequence similarity 134 member B; protein FAM134B; reticulophagy receptor 1; reticulophagy receptor FAM134B; reticulophagy regulator 1", "tax_id": 9913, "disease": "", "pathway": " (bta:540068)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "Endoplasmic reticulum (ER)-anchored autophagy regulator which mediates ER delivery into lysosomes through sequestration into autophagosomes. Promotes membrane remodeling and ER scission via its membrane bending capacity and targets the fragments into autophagosomes via interaction with ATG8 family proteins. Active under basal conditions. Required for collagen quality control in a LIR motif-dependent manner. Required for long-term survival of nociceptive and autonomic ganglion neurons., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A5PJF3", "ec_number_list": "", "go_molecular_function": "GO:0140506 endoplasmic reticulum-autophagosome adaptor activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane;GO:0005801 cis-Golgi network", "go_biological_process": "GO:0019233 sensory perception of pain;GO:0043524 negative regulation of neuron apoptotic process;GO:0061709 reticulophagy", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q5E9K8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3ZBU2-1", "uniprot_id": "CISD1_BOVIN", "mass": 11983.0, "length": 106, "protein_name": "CDGSH iron-sulfur domain-containing protein 1", "gene_name": "CISD1", "organism": "Bovine", "refseq_name": "CDGSH iron-sulfur domain-containing protein 1", "refseq_ac": "NP_001029229", "gene_names_uniprotkb": "CISD1; ZCD1", "gene_names_refseq": "CISD1", "protein_names_uniprotkb": "CDGSH iron-sulfur domain-containing protein 1; 2.6.1.3; Cysteine transaminase CISD1; MitoNEET", "protein_names_refseq": "CDGSH iron-sulfur domain-containing protein 1; cysteine transaminase CISD1; mitoNEET", "tax_id": 9913, "disease": "", "pathway": " (bta:531444)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "14570702", "class_list": "", "function": "L-cysteine transaminase that catalyzes the reversible transfer of the amino group from L-cysteine to the alpha-keto acid 2-oxoglutarate to respectively form 2-oxo-3-sulfanylpropanoate and L-glutamate (By similarity). The catalytic cycle occurs in the presence of pyridoxal 5'-phosphate (PLP) cofactor that facilitates transamination by initially forming an internal aldimine with the epsilon-amino group of active site Lys-55 residue on the enzyme (PLP-enzyme aldimine), subsequently displaced by formation of an external aldimine with the substrate amino group (PLP-L-cysteine aldimine). The external aldimine is further deprotonated to form a carbanion intermediate, which in the presence of 2-oxoglutarate regenerates PLP yielding final products 2-oxo-3-sulfanylpropanoate and L-glutamate. The proton transfer in carbanion intermediate is suggested to be controlled by the active site lysine residue, whereas PLP stabilizes carbanion structure through electron delocalization, also known as the electron sink effect (By similarity). Plays a key role in regulating maximal capacity for electron transport and oxidative phosphorylation (By similarity). May be involved in iron-sulfur cluster shuttling and/or in redox reactions. Can transfer the [2Fe-2S] cluster to an apo-acceptor protein only when in the oxidation state, likely serving as a redox sensor that regulates mitochondrial iron-sulfur cluster assembly and iron trafficking upon oxidative stress (By similarity)., [UniProtKB, UniProtKB, UniProtKB]; MitoNEET is located in the mitochondrial fraction of bovine brain., [RefSeq, PubMed]; Regulator of autophagy that contributes to antagonize BECN1-mediated cellular autophagy at the endoplasmic reticulum. Participates in the interaction of BCL2 with BECN1 and is required for BCL2-mediated depression of endoplasmic reticulum Ca(2+) stores during autophagy., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.6.1.1;2.6.1.3", "go_molecular_function": "GO:0030170 pyridoxal phosphate binding;GO:0042803 protein homodimerization activity;GO:0046872 metal ion binding;GO:0047801 L-cysteine transaminase activity;GO:0051537 2 iron, 2 sulfur cluster binding", "go_cellular_component": "GO:0005741 mitochondrial outer membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0010506 regulation of autophagy;GO:0006879 intracellular iron ion homeostasis;GO:0051604 protein maturation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q3ZBU2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3T0C6-1", "uniprot_id": "AT1B3_BOVIN", "mass": 31521.0, "length": 279, "protein_name": "Sodium/potassium-transporting ATPase subunit beta-3", "gene_name": "ATP1B3", "organism": "Bovine", "refseq_name": "sodium/potassium-transporting ATPase subunit beta-3", "refseq_ac": "NP_001030470", "gene_names_uniprotkb": "ATP1B3", "gene_names_refseq": "ATP1B3", "protein_names_uniprotkb": "Sodium/potassium-transporting ATPase subunit beta-3; ATPB-3; Sodium/potassium-dependent ATPase subunit beta-3", "protein_names_refseq": "ATPB-3; ATPase, Na+/K+ transporting, beta 3 polypeptide; sodium/potassium-dependent ATPase subunit beta-3; sodium/potassium-transporting ATPase subunit beta-3", "tax_id": 9913, "disease": "", "pathway": " (bta:532844); (R-BTA-5578775); (R-BTA-936837)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The exact function of the beta-3 subunit is not known., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0030674 protein-macromolecule adaptor activity;GO:0051117 ATPase binding;GO:0001671 ATPase activator activity;GO:0141109 transporter activator activity", "go_cellular_component": "GO:0016323 basolateral plasma membrane;GO:0016324 apical plasma membrane;GO:0042470 melanosome;GO:0036126 sperm flagellum;GO:0005890 sodium:potassium-exchanging ATPase complex", "go_biological_process": "GO:0072659 protein localization to plasma membrane;GO:0050821 protein stabilization;GO:0006883 intracellular sodium ion homeostasis;GO:0030007 intracellular potassium ion homeostasis;GO:0036376 sodium ion export across plasma membrane", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q3T0C6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q5E9L5-1", "uniprot_id": "ANM6_BOVIN", "mass": 41868.0, "length": 375, "protein_name": "Protein arginine N-methyltransferase 6", "gene_name": "PRMT6", "organism": "Bovine", "refseq_name": "protein arginine N-methyltransferase 6", "refseq_ac": "NP_001014962", "gene_names_uniprotkb": "PRMT6; HRMT1L6", "gene_names_refseq": "HRMT1L6; PRMT6", "protein_names_uniprotkb": "Protein arginine N-methyltransferase 6; 2.1.1.319; Histone-arginine N-methyltransferase PRMT6", "protein_names_refseq": "HMT1 hnRNP methyltransferase-like 6; histone-arginine N-methyltransferase PRMT6; protein arginine N-methyltransferase 6", "tax_id": 9913, "disease": "", "pathway": " (bta:540228); (R-BTA-3214858); (R-BTA-8936459)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "Arginine methyltransferase that can catalyze the formation of both omega-N monomethylarginine (MMA) and asymmetrical dimethylarginine (aDMA), with a strong preference for the formation of aDMA. Preferentially methylates arginyl residues present in a glycine and arginine-rich domain and displays preference for monomethylated substrates. Specifically mediates the asymmetric dimethylation of histone H3 'Arg-2' to form H3R2me2a. H3R2me2a represents a specific tag for epigenetic transcriptional repression and is mutually exclusive with methylation on histone H3 'Lys-4' (H3K4me2 and H3K4me3). Acts as a transcriptional repressor of various genes such as HOXA2, THBS1 and TP53 (By similarity). Repression of TP53 blocks cellular senescence (By similarity). Also methylates histone H2A and H4 'Arg-3' (H2AR3me and H4R3me, respectively). Acts as a regulator of DNA base excision during DNA repair by mediating the methylation of DNA polymerase beta (POLB), leading to the stimulation of its polymerase activity by enhancing DNA binding and processivity. Methylates HMGA1. Regulates alternative splicing events. Acts as a transcriptional coactivator of a number of steroid hormone receptors including ESR1, ESR2, PGR and NR3C1. Promotes fasting-induced transcriptional activation of the gluconeogenic program through methylation of the CRTC2 transcription coactivator. Methylates GPS2, protecting GPS2 from ubiquitination and degradation. Methylates SIRT7, inhibiting SIRT7 histone deacetylase activity and promoting mitochondria biogenesis (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.1.1.319;3.5.1.-;3.5.1.98", "go_molecular_function": "GO:0003682 chromatin binding;GO:0016274 protein-arginine N-methyltransferase activity;GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity;GO:0042054 histone methyltransferase activity;GO:0042393 histone binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005730 nucleolus", "go_biological_process": "GO:0006281 DNA repair;GO:0006338 chromatin remodeling;GO:0006351 DNA-templated transcription;GO:0006355 regulation of DNA-templated transcription;GO:0045892 negative regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q5E9L5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3ZCC9-1", "uniprot_id": "SEC13_BOVIN", "mass": 35472.0, "length": 322, "protein_name": "Protein SEC13 homolog", "gene_name": "SEC13", "organism": "Bovine", "refseq_name": "protein SEC13 homolog", "refseq_ac": "NP_001069033", "gene_names_uniprotkb": "SEC13; SEC13L1", "gene_names_refseq": "SEC13", "protein_names_uniprotkb": "Protein SEC13 homolog; GATOR2 complex protein SEC13; SEC13-like protein 1", "protein_names_refseq": "GATOR complex protein SEC13; GATOR2 complex protein SEC13; SEC13-like protein 1; protein SEC13 homolog", "tax_id": 9913, "disease": "", "pathway": " (bta:512530); (R-BTA-141430); (R-BTA-141444); (R-BTA-159227); (R-BTA-159230); (R-BTA-159231); (R-BTA-159236); (R-BTA-1855170); (R-BTA-1855196); (R-BTA-1855229); (R-BTA-191859); (R-BTA-204005); (R-BTA-2132295); (R-BTA-2467813); (R-BTA-2500257); (R-BTA-3108214); (R-BTA-3232142); (R-BTA-3301854); (R-BTA-3371453); (R-BTA-4085377); (R-BTA-4551638); (R-BTA-4570464); (R-BTA-5663220); (R-BTA-9615933); (R-BTA-9639288); (R-BTA-9648025); (R-BTA-983170)", "pathway_count": 27, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "As a component of the GATOR2 complex, functions as an activator of the amino acid-sensing branch of the mTORC1 signaling pathway. The GATOR2 complex indirectly activates mTORC1 through the inhibition of the GATOR1 subcomplex. GATOR2 probably acts as an E3 ubiquitin-protein ligase toward GATOR1. In the presence of abundant amino acids, the GATOR2 complex mediates ubiquitination of the NPRL2 core component of the GATOR1 complex, leading to GATOR1 inactivation. In the absence of amino acids, GATOR2 is inhibited, activating the GATOR1 complex. Within the GATOR2 complex, SEC13 and SEH1L are required to stabilize the complex., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Functions as a component of the nuclear pore complex (NPC) and the COPII coat. At the endoplasmic reticulum, SEC13 is involved in the biogenesis of COPII-coated vesicles (By similarity). Required for the exit of adipsin (CFD/ADN), an adipocyte-secreted protein from the endoplasmic reticulum (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005198 structural molecule activity", "go_cellular_component": "GO:0031080 nuclear pore outer ring;GO:0005765 lysosomal membrane;GO:0005789 endoplasmic reticulum membrane;GO:0030127 COPII vesicle coat;GO:0061700 GATOR2 complex", "go_biological_process": "GO:1904263 positive regulation of TORC1 signaling;GO:0072659 protein localization to plasma membrane;GO:0031669 cellular response to nutrient levels;GO:0032008 positive regulation of TOR signaling;GO:0051028 mRNA transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q3ZCC9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3ZCH0-1", "uniprot_id": "HSPA9_BOVIN", "mass": 73742.0, "length": 679, "protein_name": "Stress-70 protein, mitochondrial", "gene_name": "HSPA9", "organism": "Bovine", "refseq_name": "stress-70 protein, mitochondrial precursor", "refseq_ac": "NP_001029696", "gene_names_uniprotkb": "HSPA9", "gene_names_refseq": "HSPA9B; HSPA9", "protein_names_uniprotkb": "Stress-70 protein, mitochondrial; 3.6.4.10; 75 kDa glucose-regulated protein; GRP-75; Heat shock 70 kDa protein 9", "protein_names_refseq": "75 kDa glucose-regulated protein; GRP-75; heat shock 70 kDa protein 9; heat shock 70kDa protein 9 (mortalin); heat shock 70kDa protein 9B (mortalin-2); stress-70 protein, mitochondrial precursor; stress-70 protein, mitochondrial", "tax_id": 9913, "disease": "", "pathway": " (bta:517535); (R-BTA-3371453); (R-BTA-6799198); (R-BTA-9837999); (R-BTA-9865881)", "pathway_count": 5, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "Mitochondrial chaperone that plays a key role in mitochondrial protein import, folding, and assembly. Plays an essential role in the protein quality control system, the correct folding of proteins, the re-folding of misfolded proteins, and the targeting of proteins for subsequent degradation. These processes are achieved through cycles of ATP binding, ATP hydrolysis, and ADP release, mediated by co-chaperones. In mitochondria, it associates with the TIM (translocase of the inner membrane) protein complex to assist in the import and folding of mitochondrial proteins (By similarity). Plays an important role in mitochondrial iron-sulfur cluster (ISC) biogenesis, interacts with and stabilizes ISC cluster assembly proteins FXN, NFU1, NFS1 and ISCU. Regulates erythropoiesis via stabilization of ISC assembly. Regulates mitochondrial calcium-dependent apoptosis by coupling two calcium channels, ITPR1 and VDAC1, at the mitochondria-associated endoplasmic reticulum (ER) membrane to facilitate calcium transport from the ER lumen to the mitochondria intermembrane space, providing calcium for the downstream calcium channel MCU, which releases it into the mitochondrial matrix (By similarity). Although primarily located in the mitochondria, it is also found in other cellular compartments. In the cytosol, it associates with proteins involved in signaling, apoptosis, or senescence. It may play a role in cell cycle regulation via its interaction with and promotion of degradation of TP53 (By similarity). May play a role in the control of cell proliferation and cellular aging (By similarity). Protects against reactive oxygen species (ROS) (By similarity). Extracellular HSPA9 plays a cytoprotective role by preventing cell lysis following immune attack by the membrane attack complex by disrupting formation of the complex (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A5D9A6", "ec_number_list": "1.4.1.3;3.6.4.12;5.6.2.4;3.6.4.13;2.7.1.23;1.1.1.35;5.3.3.21;2.3.2.27;2.7.11.-;7.2.2.-;2.7.7.7;2.7.7.49;3.6.1.5;3.6.4.6;3.6.4.10;3.4.21.53;5.6.2.3;3.6.5.-;5.6.2.-;2.7.4.3;3.6.4.-;2.3.1.37;1.2.4.1;2.7.11.1;3.1.-.-;4.2.99.18;5.6.1.6;3.6.1.15;5.3.3.8;7.6.2.1;2.3.1.41;1.8.1.4;6.1.1.5;3.5.3.1;5.6.1.7;1.1.1.62;1.1.1.239;1.1.1.178;1.1.1.53;1.1.1.159;7.1.2.2;7.1.1.2;3.1.3.1;3.9.1.1;2.3.1.168;2.3.1.-;7.1.1.8;1.2.1.3;4.2.1.3;4.98.1.1;1.1.1.30;1.1.1.42;1.16.3.1;1.3.8.5;5.6.2.5;1.2.4.2;2.3.3.1;2.3.1.9;3.4.21.92;2.3.3.10;3.4.24.-;3.6.-.-;3.6.1.-;6.4.1.3;1.1.1.37;6.2.1.-;6.2.1.4;3.1.4.-;1.3.8.1", "go_molecular_function": "GO:0005524 ATP binding;GO:0051082 unfolded protein binding;GO:0016887 ATP hydrolysis activity;GO:0031072 heat shock protein binding;GO:0031625 ubiquitin protein ligase binding", "go_cellular_component": "GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix;GO:0042645 mitochondrial nucleoid", "go_biological_process": "GO:0016226 iron-sulfur cluster assembly;GO:1902037 negative regulation of hematopoietic stem cell differentiation;GO:0030218 erythrocyte differentiation;GO:0036444 calcium import into the mitochondrion;GO:0042026 protein refolding", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q3ZCH0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3ZBJ6-1", "uniprot_id": "BEX3_BOVIN", "mass": 13249.0, "length": 112, "protein_name": "Protein BEX3", "gene_name": "BEX3", "organism": "Bovine", "refseq_name": "protein BEX3", "refseq_ac": "NP_001157249", "gene_names_uniprotkb": "BEX3; NADE; NGFRAP1", "gene_names_refseq": "BEX3; NGFRAP1; WBP5", "protein_names_uniprotkb": "Protein BEX3; Brain-expressed X-linked protein 3 homolog; Nerve growth factor receptor-associated protein 1; p75NTR-associated cell death executor", "protein_names_refseq": "WW domain binding protein 5; brain-expressed X-linked protein 3 homolog; nerve growth factor receptor (TNFRSF16) associated protein 1; nerve growth factor receptor-associated protein 1; p75NTR-associated cell death executor; protein BEX3", "tax_id": 9913, "disease": "", "pathway": " (bta:100034674); (R-BTA-205025)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "May be a signaling adapter molecule involved in NGFR/p75NTR-mediated apoptosis induced by NGF. Plays a role in zinc-triggered neuronal death. In absence of reductive stress, acts as a pseudosubstrate for the CRL2(FEM1B) complex: associates with FEM1B via zinc, thereby preventing association between FEM1B and its substrates., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005102 signaling receptor binding;GO:0046872 metal ion binding;GO:0140678 molecular function inhibitor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0007165 signal transduction;GO:0006915 apoptotic process;GO:0031397 negative regulation of protein ubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q3ZBJ6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q58DH7-1", "uniprot_id": "SGMR1_BOVIN", "mass": 24914.0, "length": 223, "protein_name": "Sigma non-opioid intracellular receptor 1", "gene_name": "SIGMAR1", "organism": "Bovine", "refseq_name": "sigma non-opioid intracellular receptor 1", "refseq_ac": "NP_001029827", "gene_names_uniprotkb": "SIGMAR1; OPRS1", "gene_names_refseq": "OPRS1; SIGMAR1", "protein_names_uniprotkb": "Sigma non-opioid intracellular receptor 1; Sigma 1-type opioid receptor; Sigma1-receptor; Sigma1R", "protein_names_refseq": "opioid receptor, sigma 1; sigma 1-type opioid receptor; sigma non-opioid intracellular receptor 1; sigma1-receptor; sigma1R", "tax_id": 9913, "disease": "", "pathway": " (bta:538903)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "16305752;25924612", "class_list": "", "function": "Functions in lipid transport from the endoplasmic reticulum and is involved in a wide array of cellular functions probably through regulation of the biogenesis of lipid microdomains at the plasma membrane. Regulates calcium efflux at the endoplasmic reticulum., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Sig1R through Rac1 signaling induces mild oxidative stress that possibly is involved in the regulation of neuroplasticity Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0038023 signaling receptor activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005811 lipid droplet;GO:0014069 postsynaptic density;GO:0016020 membrane;GO:0030426 growth cone", "go_biological_process": "GO:0006869 lipid transport;GO:0070207 protein homotrimerization;GO:0043523 regulation of neuron apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q58DH7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q58CT8-1", "uniprot_id": "LAX1_BOVIN", "mass": 41859.0, "length": 387, "protein_name": "Lymphocyte transmembrane adapter 1", "gene_name": "LAX1", "organism": "Bovine", "refseq_name": "lymphocyte transmembrane adapter 1", "refseq_ac": "NP_001015674", "gene_names_uniprotkb": "LAX1; LAX", "gene_names_refseq": "LAX1; LAX", "protein_names_uniprotkb": "Lymphocyte transmembrane adapter 1; Membrane-associated adapter protein LAX", "protein_names_refseq": "lymphocyte transmembrane adapter 1; membrane associated adaptor protein LAX; membrane-associated adapter protein LAX", "tax_id": 9913, "disease": "", "pathway": " (bta:540424)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "Negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells and BCR (B-cell antigen receptor)-mediated signaling in B-cells., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0019901 protein kinase binding;GO:0042169 SH2 domain binding", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0005829 cytosol;GO:0005886 plasma membrane", "go_biological_process": "GO:0046649 lymphocyte activation;GO:0006955 immune response;GO:0035556 intracellular signal transduction;GO:0042113 B cell activation;GO:0002250 adaptive immune response", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q58CT8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q5EA06-1", "uniprot_id": "GBRP_BOVIN", "mass": 50430.0, "length": 440, "protein_name": "Gamma-aminobutyric acid receptor subunit pi", "gene_name": "GABRP", "organism": "Bovine", "refseq_name": "gamma-aminobutyric acid receptor subunit pi precursor", "refseq_ac": "NP_001015618", "gene_names_uniprotkb": "GABRP", "gene_names_refseq": "GABRP", "protein_names_uniprotkb": "Gamma-aminobutyric acid receptor subunit pi; GABA(A) receptor subunit pi; GABAAR subunit pi", "protein_names_refseq": "GABA(A) receptor subunit pi; GABAAR subunit pi; gamma-aminobutyric acid (GABA) A receptor, pi; gamma-aminobutyric acid receptor subunit pi precursor; gamma-aminobutyric acid receptor subunit pi; gamma-aminobutyric acid type A receptor pi subunit", "tax_id": 9913, "disease": "", "pathway": " (bta:517459)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "Pi subunit of the heteropentameric ligand-gated chloride channel gated by gamma-aminobutyric acid (GABA). GABA-gated chloride channels, also named GABA(A) receptors (GABAAR), consist of five subunits arranged around a central pore and contain GABA active binding site(s) located at the alpha and beta subunit interfaces. When activated by GABA, GABAARs selectively allow the flow of chloride anions across the cell membrane down their electrochemical gradient. Pi-containing GABAARs are mostly located in peripheral tissues. In the uterus, pi subunits modulate uterus contraction by altering the sensitivity of GABAARs to pregnanolone. In the lungs, pi-containing GABAARs contribute to pulmonary fluid transport via luminal secretion of chloride., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 5, "predicted_n_glycosites": 5, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "5.6.1.6;1.8.-.-;1.8.5.1", "go_molecular_function": "GO:0004890 GABA-A receptor activity;GO:0022851 GABA-gated chloride ion channel activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0045202 synapse;GO:0016324 apical plasma membrane;GO:0034707 chloride channel complex;GO:1902711 GABA-A receptor complex", "go_biological_process": "GO:1902476 chloride transmembrane transport;GO:0051932 synaptic transmission, GABAergic", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q5EA06-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3T0K9-1", "uniprot_id": "DAZP2_BOVIN", "mass": 17319.0, "length": 168, "protein_name": "DAZ-associated protein 2", "gene_name": "DAZAP2", "organism": "Bovine", "refseq_name": "DAZ-associated protein 2", "refseq_ac": "NP_001029873", "gene_names_uniprotkb": "DAZAP2; PRTB", "gene_names_refseq": "DAZAP2", "protein_names_uniprotkb": "DAZ-associated protein 2; Deleted in azoospermia-associated protein 2; Proline-rich transcript in brain protein", "protein_names_refseq": "DAZ-associated protein 2; deleted in azoospermia-associated protein 2; proline-rich transcript in brain protein", "tax_id": 9913, "disease": "", "pathway": " (bta:540286)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "In unstressed cells, promotes SIAH1-mediated polyubiquitination and degradation of the serine/threonine-protein kinase HIPK2, probably by acting as a loading factor that potentiates complex formation between HIPK2 and ubiquitin ligase SIAH1 (By similarity). In response to DNA damage, localizes to the nucleus following phosphorylation by HIPK2 and modulates the expression of a subset of TP53/p53 target genes by binding to TP53 at target gene promoters (By similarity). This limits the expression of a number of cell death-mediating TP53 target genes, reducing DNA damage-induced cell death (By similarity). Enhances the binding of transcription factor TCF7L2/TCF4, a Wnt signaling pathway effector, to the promoters of target genes (By similarity). Plays a role in stress granule formation (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003713 transcription coactivator activity;GO:0042802 identical protein binding;GO:0031625 ubiquitin protein ligase binding;GO:0050699 WW domain binding;GO:0030971 receptor tyrosine kinase binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0016607 nuclear speck;GO:0016604 nuclear body;GO:0010494 cytoplasmic stress granule", "go_biological_process": "GO:0031648 protein destabilization;GO:0034063 stress granule assembly", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q3T0K9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q863B3-1", "uniprot_id": "SND1_BOVIN", "mass": 101989.0, "length": 910, "protein_name": "Staphylococcal nuclease domain-containing protein 1", "gene_name": "SND1", "organism": "Bovine", "refseq_name": "staphylococcal nuclease domain-containing protein 1", "refseq_ac": "NP_991353", "gene_names_uniprotkb": "SND1", "gene_names_refseq": "SND1", "protein_names_uniprotkb": "Staphylococcal nuclease domain-containing protein 1; 100 kDa coactivator; 3.1.31.1; p100 co-activator", "protein_names_refseq": "100 kDa coactivator; p100 co-activator; staphylococcal nuclease domain-containing protein 1", "tax_id": 9913, "disease": "", "pathway": " (bta:404098)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "11691653;26694361", "class_list": "", "function": "Endonuclease that mediates miRNA decay of both protein-free and AGO2-loaded miRNAs (By similarity). As part of its function in miRNA decay, regulates mRNAs involved in G1-to-S phase transition (By similarity). Functions as a bridging factor between STAT6 and the basal transcription factor (By similarity). Plays a role in PIM1 regulation of MYB activity (By similarity). Functions as a transcriptional coactivator for STAT5 (By similarity)., [UniProtKB, UniProtKB, UniProtKB]; Endonuclease that mediates miRNA decay of both protein-free and AGO2-loaded miRNAs. As part of its function in miRNA decay, regulates mRNAs involved in G1-to-S phase transition. Functions as a bridging factor between STAT6 and the basal transcription factor. Plays a role in PIM1 regulation of MYB activity. Functions as a transcriptional coactivator for STAT5., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; These results suggest the key role of Tudor-SN in the transcriptional regulation of milk synthesis and proliferation of bovine mammary epithelial cells under the stimulation of amino acids and hormones. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 7, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q3MHZ9", "ec_number_list": "", "go_molecular_function": "GO:1905172 RISC complex binding;GO:0003723 RNA binding;GO:0004521 RNA endonuclease activity;GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0042470 melanosome;GO:0097433 dense body;GO:0031332 RNAi effector complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006402 mRNA catabolic process;GO:0031047 regulatory ncRNA-mediated gene silencing;GO:0010564 regulation of cell cycle process;GO:0010587 miRNA catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q863B3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q5NDF2-1", "uniprot_id": "PMGT2_BOVIN", "mass": 66067.0, "length": 580, "protein_name": "Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2", "gene_name": "POMGNT2", "organism": "Bovine", "refseq_name": "protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2", "refseq_ac": "NP_001011682", "gene_names_uniprotkb": "POMGNT2; AGO61; GTDC2", "gene_names_refseq": "AGO61; C22H3orf39; C3orf39; GTDC2; POMGNT2", "protein_names_uniprotkb": "Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2; 2.4.1.312; Extracellular O-linked N-acetylglucosamine transferase-like; Glycosyltransferase-like domain-containing protein 2; POMGnT2", "protein_names_refseq": "glycosyltransferase ago61; glycosyltransferase-like domain containing 2; glycosyltransferase-like domain-containing protein 2; protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2", "tax_id": 9913, "disease": "", "pathway": " (bta:497030); (R-BTA-8932505)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "O-linked mannose beta-1,4-N-acetylglucosaminyltransferase that transfers UDP-N-acetyl-D-glucosamine to the 4-position of the mannose to generate N-acetyl-D-glucosamine-beta-1,4-O-D-mannosylprotein. Involved in the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 4, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 4, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 4, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "Q08DC6", "ec_number_list": "2.4.1.312", "go_molecular_function": "GO:0097363 protein O-acetylglucosaminyltransferase activity;GO:0008375 acetylglucosaminyltransferase activity;GO:0016757 glycosyltransferase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0001764 neuron migration;GO:0006493 protein O-linked glycosylation;GO:0035269 protein O-linked glycosylation via mannose", "synthesized_glycan_count": 85, "hit_score": 0.5, "record_id": "Q5NDF2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3ZC64-1", "uniprot_id": "EFNA1_BOVIN", "mass": 23838.0, "length": 205, "protein_name": "Ephrin-A1", "gene_name": "EFNA1", "organism": "Bovine", "refseq_name": "ephrin-A1 precursor", "refseq_ac": "NP_001029464", "gene_names_uniprotkb": "EFNA1", "gene_names_refseq": "EFNA1", "protein_names_uniprotkb": "Ephrin-A1", "protein_names_refseq": "ephrin-A1 precursor", "tax_id": 9913, "disease": "", "pathway": " (bta:507319); (R-BTA-2682334); (R-BTA-3928663); (R-BTA-3928665)", "pathway_count": 4, "publication_count": 2, "publication_id_list": "28777434;30238980", "class_list": "", "function": "Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. Involved in angiogenesis, regulating vascular endothelial cell differentiation and migration through activation of EPHA2. Acts as a ligand for EPHA3, inhibiting epithelial-to-mesenchymal transition of cardiac cells and playing a role in heart development. May also contribute to dendritic spine morphogenesis., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Eph A-ephrin A1 system is a positive factor in the increase and maintenance of epithelial cells in mammary glands of cows; the signaling system contributes to development, remodeling, and functionality of normal mammary glands and could overcome mastitis., [RefSeq, PubMed]; Ephrin A1 promotes the development of bovine endometrial epithelial cells and likely enhances uterine capacity and maintenance of pregnancy by activating mitogen-activated protein kinase and phosphoinositide 3-kinase signaling cascades and by restoring endoplasmic reticulum stress., [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0046875 ephrin receptor binding;GO:0048018 receptor ligand activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0005886 plasma membrane;GO:0005925 focal adhesion;GO:0098552 side of membrane", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0001525 angiogenesis;GO:0043535 regulation of blood vessel endothelial cell migration;GO:0048013 ephrin receptor signaling pathway;GO:1902004 positive regulation of amyloid-beta formation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q3ZC64-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q5EAD3-1", "uniprot_id": "NFE2_BOVIN", "mass": 41390.0, "length": 374, "protein_name": "Transcription factor NF-E2 45 kDa subunit", "gene_name": "NFE2", "organism": "Bovine", "refseq_name": "transcription factor NF-E2 45 kDa subunit", "refseq_ac": "NP_001014923", "gene_names_uniprotkb": "NFE2", "gene_names_refseq": "NFE2", "protein_names_uniprotkb": "Transcription factor NF-E2 45 kDa subunit; Leucine zipper protein NF-E2; Nuclear factor, erythroid-derived 2 45 kDa subunit; p45 NF-E2", "protein_names_refseq": "leucine zipper protein NF-E2; nuclear factor (erythroid-derived 2), 45kDa; nuclear factor, erythroid derived 2; nuclear factor, erythroid-derived 2 45 kDa subunit; p45 NF-E2; transcription factor NF-E2 45 kDa subunit", "tax_id": 9913, "disease": "", "pathway": " (bta:514006); (R-BTA-983231)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "16305752;33150387", "class_list": "", "function": "Cellular and Transcriptional Adaptation of Bovine Granulosa Cells Under Ethanol-Induced Stress In Vitro., [RefSeq, PubMed]; Component of the NF-E2 complex essential for regulating erythroid and megakaryocytic maturation and differentiation. Binds to the hypersensitive site 2 (HS2) of the beta-globin control region (LCR). This subunit (NFE2) recognizes the TCAT/C sequence of the AP-1-like core palindrome present in a number of erythroid and megakaryocytic gene promoters. Requires MAFK or other small MAF proteins for binding to the NF-E2 motif. May play a role in all aspects of hemoglobin production from globin and heme synthesis to procurement of iron (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003700 DNA-binding transcription factor activity;GO:0042802 identical protein binding;GO:0050699 WW domain binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0032993 protein-DNA complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q5EAD3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q5E9M1-1", "uniprot_id": "PRAF3_BOVIN", "mass": 21666.0, "length": 188, "protein_name": "PRA1 family protein 3", "gene_name": "ARL6IP5", "organism": "Bovine", "refseq_name": "PRA1 family protein 3", "refseq_ac": "NP_001014891", "gene_names_uniprotkb": "ARL6IP5; PRAF3", "gene_names_refseq": "ARL6IP5", "protein_names_uniprotkb": "PRA1 family protein 3; ADP-ribosylation factor-like protein 6-interacting protein 5; ARL-6-interacting protein 5; Aip-5", "protein_names_refseq": "ADP-ribosylation factor-like 6 interacting protein 5; ADP-ribosylation factor-like protein 6-interacting protein 5; ADP-ribosylation-like factor 6 interacting protein 5; ARL-6-interacting protein 5; PRA1 family protein 3; aip-5", "tax_id": 9913, "disease": "", "pathway": " (bta:509977); (R-BTA-210500)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "Regulates intracellular concentrations of taurine and glutamate. Negatively modulates SLC1A1/EAAC1 glutamate transport activity by decreasing its affinity for glutamate in a PKC activity-dependent manner. Plays a role in the retention of SLC1A1/EAAC1 in the endoplasmic reticulum., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005856 cytoskeleton;GO:0005886 plasma membrane;GO:0016020 membrane;GO:0005789 endoplasmic reticulum membrane;GO:0099523 presynaptic cytosol", "go_biological_process": "GO:0002037 negative regulation of L-glutamate import across plasma membrane;GO:0043065 positive regulation of apoptotic process;GO:0010917 negative regulation of mitochondrial membrane potential;GO:0051051 negative regulation of transport;GO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q5E9M1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3T149-1", "uniprot_id": "HSPB1_BOVIN", "mass": 22393.0, "length": 201, "protein_name": "Heat shock protein beta-1", "gene_name": "HSPB1", "organism": "Bovine", "refseq_name": "heat shock protein beta-1", "refseq_ac": "NP_001020740", "gene_names_uniprotkb": "HSPB1; HSP27", "gene_names_refseq": "HSP 27; HSPB1", "protein_names_uniprotkb": "Heat shock protein beta-1; HSP 27; Heat shock 27 kDa protein; HspB1", "protein_names_refseq": "heat shock 27 kDa protein 1; heat shock 27kDa protein 1; heat shock protein beta-1", "tax_id": 9913, "disease": "", "pathway": " (bta:516099); (R-BTA-4420097); (R-BTA-450408); (R-BTA-5687128); (R-BTA-9009391)", "pathway_count": 5, "publication_count": 3, "publication_id_list": "15304367;21594731;24563320", "class_list": "", "function": "CaMKII is required for redox-sensitive activation of p38 MAPK/heat shock protein 27 pathway and ERK1/2, [RefSeq, PubMed]; HSPB1 could have an important role during testosterone-related myogenesis., [RefSeq, PubMed]; Small heat shock protein which functions as a molecular chaperone probably maintaining denatured proteins in a folding-competent state. Plays a role in stress resistance and actin organization. Through its molecular chaperone activity may regulate numerous biological processes including the phosphorylation and the axonal transport of neurofilament proteins., [UniProtKB, UniProtKB]; These findings suggest that HSPB1 mediates androgen signaling by binding directly to androgen receptor and then enhancing androgen-mediated myogenesis in myogenic cells., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 10, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0042802 identical protein binding;GO:0042803 protein homodimerization activity;GO:0051082 unfolded protein binding;GO:0005080 protein kinase C binding;GO:0008426 protein kinase C inhibitor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005819 spindle;GO:0005829 cytosol;GO:0030018 Z disc", "go_biological_process": "GO:0099641 anterograde axonal protein transport;GO:2001028 positive regulation of endothelial cell chemotaxis;GO:0035556 intracellular signal transduction;GO:0043066 negative regulation of apoptotic process;GO:0045766 positive regulation of angiogenesis", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q3T149-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q58CS6-1", "uniprot_id": "IFT20_BOVIN", "mass": 17847.0, "length": 156, "protein_name": "Intraflagellar transport protein 20 homolog", "gene_name": "IFT20", "organism": "Bovine", "refseq_name": "intraflagellar transport protein 20 homolog", "refseq_ac": "NP_001013621", "gene_names_uniprotkb": "IFT20", "gene_names_refseq": "IFT20", "protein_names_uniprotkb": "Intraflagellar transport protein 20 homolog", "protein_names_refseq": "intraflagellar transport 20 homolog; intraflagellar transport protein 20 homolog", "tax_id": 9913, "disease": "", "pathway": " (bta:445364); (R-BTA-5620924)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "11916979;12821668;16305752", "class_list": "", "function": "IFT20 is an intraflagellar transport protein that appears to bridge kinesin II with the IFT complex., [RefSeq, PubMed]; Part of intraflagellar transport (IFT) particles involved in ciliary process assembly. May play a role in the trafficking of ciliary membrane proteins from the Golgi complex to the cilium. Regulates the platelet-derived growth factor receptor-alpha (PDGFRA) signaling pathway. Required for protein stability of E3 ubiquitin ligases CBL and CBLB that mediate ubiquitination and internalization of PDGFRA for proper feedback inhibition of PDGFRA signaling. Essential for male fertility. Plays an important role in spermatogenesis, particularly spermiogenesis, when germ cells form flagella. May play a role in the transport of flagellar proteins ODF2 and SPAG16 to build sperm flagella and in the removal of redundant sperm cytoplasm. Also involved in autophagy since it is required for trafficking of ATG16L and the expansion of the autophagic compartment., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0031267 small GTPase binding;GO:0002046 opsin binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005794 Golgi apparatus;GO:0005813 centrosome;GO:0005929 cilium;GO:0031514 motile cilium", "go_biological_process": "GO:0007283 spermatogenesis;GO:0030154 cell differentiation;GO:0060271 cilium assembly;GO:0061512 protein localization to cilium;GO:1902017 regulation of cilium assembly", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q58CS6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q4U5R4-1", "uniprot_id": "RN114_BOVIN", "mass": 25669.0, "length": 230, "protein_name": "E3 ubiquitin-protein ligase RNF114", "gene_name": "RNF114", "organism": "Bovine", "refseq_name": "E3 ubiquitin-protein ligase RNF114", "refseq_ac": "NP_001019702", "gene_names_uniprotkb": "RNF114; ZNF313", "gene_names_refseq": "RNF114; Znf313", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase RNF114; 2.3.2.27; RING finger protein 114; RING-type E3 ubiquitin transferase RNF114; Zinc finger protein 313", "protein_names_refseq": "E3 ubiquitin-protein ligase RNF114; RING-type E3 ubiquitin transferase RNF114; zinc finger protein 313", "tax_id": 9913, "disease": "", "pathway": " (bta:513479); (R-BTA-983168)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "E3 ubiquitin-protein ligase that promotes the ubiquitination of various substrates. In turn, participates in the regulation of many biological processes including cell cycle, apoptosis, osteoclastogenesis as well as innate or adaptive immunity. Acts as negative regulator of NF-kappa-B-dependent transcription by promoting the ubiquitination and stabilization of the NF-kappa-B inhibitor TNFAIP3. May promote the ubiquitination of TRAF6 as well. Also acts as a negative regulator of T-cell activation. Inhibits cellular dsRNA responses and interferon production by targeting MAVS component for proteasomal degradation. Ubiquitinates the CDK inhibitor CDKN1A leading to its degradationand probably also CDKN1B and CDKN1C. This activity stimulates cell cycle G1-to-S phase transition and suppresses cellular senescence. May play a role in spermatogenesis., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A5D9G2;Q3T0F8", "ec_number_list": "2.3.2.27;2.3.2.23;2.3.2.31;2.3.2.26;2.3.2.-;2.3.2.34;2.3.2.25;2.3.2.24", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol", "go_biological_process": "GO:0007283 spermatogenesis;GO:0030154 cell differentiation;GO:0000209 protein polyubiquitination;GO:0006511 ubiquitin-dependent protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q4U5R4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q5E9B5-1", "uniprot_id": "ACTH_BOVIN", "mass": 41877.0, "length": 376, "protein_name": "Actin, gamma-enteric smooth muscle", "gene_name": "ACTG2", "organism": "Bovine", "refseq_name": "actin, gamma-enteric smooth muscle", "refseq_ac": "NP_001013610", "gene_names_uniprotkb": "ACTG2", "gene_names_refseq": "ACTG2", "protein_names_uniprotkb": "Actin, gamma-enteric smooth muscle; 3.6.4.-; Gamma-2-actin; Smooth muscle gamma-actin", "protein_names_refseq": "actin, gamma 2, smooth muscle, enteric; actin, gamma-enteric smooth muscle; gamma-2-actin; smooth muscle gamma-actin", "tax_id": 9913, "disease": "", "pathway": " (bta:281595); (R-BTA-445355); (R-BTA-9764561); (R-BTA-9913351); (R-BTA-9958825)", "pathway_count": 5, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.6.4.12;5.6.2.4;3.6.4.13;2.3.2.27;7.2.2.-;2.7.7.7;2.7.7.49;3.6.1.5;3.6.4.6;3.6.4.10;5.6.2.3;3.6.5.-;5.6.2.-;2.7.4.3;3.6.4.-;2.7.11.1;3.1.-.-;4.2.99.18;5.6.1.6;3.6.1.15;7.6.2.1;3.1.3.1;3.9.1.1;5.6.2.5;3.4.24.-;3.6.-.-;3.6.1.-;5.6.1.7;3.1.4.-;3.4.21.53", "go_molecular_function": "GO:0005200 structural constituent of cytoskeleton;GO:0005524 ATP binding;GO:0016787 hydrolase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0015629 actin cytoskeleton;GO:0030027 lamellipodium;GO:0030175 filopodium", "go_biological_process": "GO:0010628 positive regulation of gene expression;GO:0090131 mesenchyme migration", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q5E9B5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3T199-1", "uniprot_id": "RS23_BOVIN", "mass": 15808.0, "length": 143, "protein_name": "Small ribosomal subunit protein uS12", "gene_name": "RPS23", "organism": "Bovine", "refseq_name": "small ribosomal subunit protein uS12", "refseq_ac": "NP_001029862", "gene_names_uniprotkb": "RPS23", "gene_names_refseq": "RPS23", "protein_names_uniprotkb": "Small ribosomal subunit protein uS12; 40S ribosomal protein S23", "protein_names_refseq": "40S ribosomal protein S23; small ribosomal subunit protein uS12", "tax_id": 9913, "disease": "", "pathway": " (bta:540129); (R-BTA-156827); (R-BTA-1799339); (R-BTA-6791226); (R-BTA-72649); (R-BTA-72689); (R-BTA-72695); (R-BTA-72702); (R-BTA-72706); (R-BTA-9629569); (R-BTA-975956); (R-BTA-975957); (R-BTA-9954714); (R-BTA-9954716)", "pathway_count": 14, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel. Plays an important role in translational accuracy. Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005791 rough endoplasmic reticulum;GO:0045202 synapse;GO:0005840 ribosome;GO:0032040 small-subunit processome;GO:0022627 cytosolic small ribosomal subunit", "go_biological_process": "GO:0006412 translation;GO:0034063 stress granule assembly;GO:1990145 maintenance of translational fidelity;GO:0002181 cytoplasmic translation;GO:0042274 ribosomal small subunit biogenesis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q3T199-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q5E9K3-1", "uniprot_id": "PNPO_BOVIN", "mass": 30366.0, "length": 261, "protein_name": "Pyridoxine-5'-phosphate oxidase", "gene_name": "PNPO", "organism": "Bovine", "refseq_name": "pyridoxine-5'-phosphate oxidase", "refseq_ac": "NP_001014907", "gene_names_uniprotkb": "PNPO", "gene_names_refseq": "PNPO", "protein_names_uniprotkb": "Pyridoxine-5'-phosphate oxidase; 1.4.3.5; Pyridoxamine-phosphate oxidase", "protein_names_refseq": "pyridoxamine-phosphate oxidase; pyridoxine-5'-phosphate oxidase", "tax_id": 9913, "disease": "", "pathway": " (bta:512573); (R-BTA-964975)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.4.3.5", "go_molecular_function": "GO:0030170 pyridoxal phosphate binding;GO:0042803 protein homodimerization activity;GO:0010181 FMN binding;GO:0004733 pyridoxamine phosphate oxidase activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0008615 pyridoxine biosynthetic process;GO:0042823 pyridoxal phosphate biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q5E9K3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q5EAE0-1", "uniprot_id": "ERGI3_BOVIN", "mass": 43375.0, "length": 383, "protein_name": "Endoplasmic reticulum-Golgi intermediate compartment protein 3", "gene_name": "ERGIC3", "organism": "Bovine", "refseq_name": "endoplasmic reticulum-Golgi intermediate compartment protein 3", "refseq_ac": "NP_001029525", "gene_names_uniprotkb": "ERGIC3", "gene_names_refseq": "ERGIC3; SDBCAG84", "protein_names_uniprotkb": "Endoplasmic reticulum-Golgi intermediate compartment protein 3", "protein_names_refseq": "endoplasmic reticulum-Golgi intermediate compartment protein 3; serologically defined breast cancer antigen 84", "tax_id": 9913, "disease": "", "pathway": " (bta:509546)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "Plays a role in transport between endoplasmic reticulum and Golgi., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Possible role in transport between endoplasmic reticulum and Golgi. Positively regulates trafficking of the secretory proteins alpha1-antitrypsin/SERPINA1 and HP/haptoglobin (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q0V8E8;Q3T0M8;Q58CR6;Q58CZ8", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005783 endoplasmic reticulum;GO:0030134 COPII-coated ER to Golgi transport vesicle;GO:0005789 endoplasmic reticulum membrane;GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane", "go_biological_process": "GO:0090316 positive regulation of intracellular protein transport;GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0006890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q5EAE0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q5EA01-1", "uniprot_id": "B4GA1_BOVIN", "mass": 47231.0, "length": 415, "protein_name": "Beta-1,4-glucuronyltransferase 1", "gene_name": "B4GAT1", "organism": "Bovine", "refseq_name": "beta-1,4-glucuronyltransferase 1", "refseq_ac": "NP_001029980", "gene_names_uniprotkb": "B4GAT1; B3GNT1; B3GNT6", "gene_names_refseq": "B3GNT1; B4GAT1", "protein_names_uniprotkb": "Beta-1,4-glucuronyltransferase 1; 2.4.1.-; I-beta-1,3-N-acetylglucosaminyltransferase; N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase; Poly-N-acetyllactosamine extension enzyme; UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1; iGnT", "protein_names_refseq": "I-beta-1,3-N-acetylglucosaminyltransferase; N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase; UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1; beta-1,3-N-acetylglucosaminyltransferase bGnT-1; beta-1,4-glucuronyltransferase 1; iGnT; poly-N-acetyllactosamine extension enzyme", "tax_id": 9913, "disease": "", "pathway": " (bta:618055); (R-BTA-2022854); (R-BTA-9939291)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "Beta-1,4-glucuronyltransferase involved in O-mannosylation of alpha-dystroglycan (DAG1). Transfers a glucuronic acid (GlcA) residue onto a xylose (Xyl) acceptor to produce the glucuronyl-beta-1,4-xylose-beta disaccharide primer, which is further elongated by LARGE1, during synthesis of phosphorylated O-mannosyl glycan. Phosphorylated O-mannosyl glycan is a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity. Required for axon guidance; via its function in O-mannosylation of alpha-dystroglycan (DAG1)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "Q3MHK2;Q58DG2", "ec_number_list": "2.4.1.-", "go_molecular_function": "GO:0046872 metal ion binding;GO:0015020 glucuronosyltransferase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005794 Golgi apparatus", "go_biological_process": "GO:0035269 protein O-linked glycosylation via mannose;GO:0009101 glycoprotein biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q5EA01-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q4PJK1-1", "uniprot_id": "KCAB1_BOVIN", "mass": 44710.0, "length": 401, "protein_name": "Voltage-gated potassium channel subunit beta-1", "gene_name": "KCNAB1", "organism": "Bovine", "refseq_name": "voltage-gated potassium channel subunit beta-1", "refseq_ac": "NP_001020507", "gene_names_uniprotkb": "KCNAB1", "gene_names_refseq": "KCNAB1; Kvbeta1.1", "protein_names_uniprotkb": "Voltage-gated potassium channel subunit beta-1; 1.1.1.-; K(+) channel subunit beta-1; Kv-beta-1", "protein_names_refseq": "K(+) channel subunit beta-1; kv-beta-1; potassium voltage-gated channel subfamily A member regulatory beta subunit 1; potassium voltage-gated channel, shaker-related subfamily, beta member 1; voltage-gated potassium channel subunit beta-1", "tax_id": 9913, "disease": "", "pathway": " (bta:526133); (R-BTA-1296072)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "21436029", "class_list": "", "function": "Oxidation of NADPH on Kvbeta1 inhibits ball-and-chain type inactivation by restraining the chain., [RefSeq, PubMed]; Regulatory subunit of the voltage-gated potassium (Kv) channels composed of pore-forming and potassium-conducting alpha subunits and of regulatory beta subunits. The beta-1/KCNAB1 cytoplasmic subunit mediates closure of delayed rectifier potassium channels by physically obstructing the pore via its N-terminal domain and increases the speed of channel closure for other family members. Promotes the inactivation of KCNA1, KCNA2, KCNA4, KCNA5 and KCNA6 alpha subunit-containing channels (By similarity). Displays nicotinamide adenine dinucleotide phosphate (NADPH)-dependent aldoketoreductase activity by catalyzing the NADPH-dependent reduction of a variety of endogenous aldehydes and ketones (By similarity). The binding of NADPH is required for efficient down-regulation of potassium channel activity (By similarity). Oxidation of the bound NADPH restrains N-terminal domain from blocking the channel, thereby decreasing N-type inactivation of potassium channel activity (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q05B86", "ec_number_list": "1.1.1.-;1.1.1.184;1.1.1.189;1.1.1.197;1.1.1.196;1.1.1.71;1.1.1.2;1.6.-.-;1.1.1.19;1.1.1.20;1.1.1.372;1.1.1.54;1.1.1.300", "go_molecular_function": "GO:0015459 potassium channel regulator activity;GO:0044325 transmembrane transporter binding;GO:0008106 alcohol dehydrogenase (NADP+) activity;GO:0070402 NADPH binding;GO:0004090 carbonyl reductase (NADPH) activity", "go_cellular_component": "GO:0034705 potassium channel complex;GO:0005829 cytosol;GO:0008076 voltage-gated potassium channel complex;GO:0009898 cytoplasmic side of plasma membrane;GO:0044224 juxtaparanode region of axon", "go_biological_process": "GO:1901379 regulation of potassium ion transmembrane transport;GO:0071805 potassium ion transmembrane transport;GO:0055085 transmembrane transport;GO:0006813 potassium ion transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q4PJK1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q5E9A1-1", "uniprot_id": "NACA_BOVIN", "mass": 23370.0, "length": 215, "protein_name": "Nascent polypeptide-associated complex subunit alpha", "gene_name": "NACA", "organism": "Bovine", "refseq_name": "nascent polypeptide-associated complex subunit alpha", "refseq_ac": "NP_001014916", "gene_names_uniprotkb": "NACA", "gene_names_refseq": "NACA", "protein_names_uniprotkb": "Nascent polypeptide-associated complex subunit alpha; Alpha-NAC; NAC-alpha", "protein_names_refseq": "NAC-alpha; alpha-NAC; nascent polypeptide-associated complex alpha subunit; nascent polypeptide-associated complex subunit alpha; nascent-polypeptide-associated complex alpha polypeptide", "tax_id": 9913, "disease": "", "pathway": " (bta:513312)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "10982809;16305752;8047162;9877153", "class_list": "", "function": "Prevents inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). Binds to nascent polypeptide chains as they emerge from the ribosome and blocks their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptides to the ER. Also reduces the inherent affinity of ribosomes for protein translocation sites in the ER membrane (M sites). May act as a specific coactivator for JUN, binding to DNA and stabilizing the interaction of JUN homodimers with target gene promoters., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 8, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q3T0K5", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0003713 transcription coactivator activity;GO:0051082 unfolded protein binding;GO:0017025 TBP-class protein binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005854 nascent polypeptide-associated complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0015031 protein transport;GO:0006612 protein targeting to membrane", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q5E9A1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3T0Q0-1", "uniprot_id": "SAT1_BOVIN", "mass": 19925.0, "length": 171, "protein_name": "Diamine acetyltransferase 1", "gene_name": "SAT1", "organism": "Bovine", "refseq_name": "diamine acetyltransferase 1", "refseq_ac": "NP_001029505", "gene_names_uniprotkb": "SAT1; SAT", "gene_names_refseq": "SAT1; SAT", "protein_names_uniprotkb": "Diamine acetyltransferase 1; 2.3.1.57; Polyamine N-acetyltransferase 1; Putrescine acetyltransferase; SSAT-1; SSAT; Spermidine/spermine N(1)-acetyltransferase 1", "protein_names_refseq": "SSAT-1; SSAT; diamine N-acetyltransferase 1; diamine acetyltransferase 1; polyamine N-acetyltransferase 1; putrescine acetyltransferase; spermidine/spermine N(1)-acetyltransferase 1", "tax_id": 9913, "disease": "", "pathway": " (bta:508861); (R-BTA-351200)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Enzyme which catalyzes the acetylation of polyamines. Substrate specificity: norspermidine = spermidine >> spermine > N(1)-acetylspermine. This highly regulated enzyme allows a fine attenuation of the intracellular concentration of polyamines. Also involved in the regulation of polyamine transport out of cells. Also acts on 1,3-diaminopropane and 1,5-diaminopentane., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.3.1.57;2.3.1.-", "go_molecular_function": "GO:0042802 identical protein binding;GO:0004145 diamine N-acetyltransferase activity;GO:0019809 spermidine binding;GO:0008080 N-acetyltransferase activity", "go_cellular_component": "GO:0005829 cytosol;GO:0005737 cytoplasm", "go_biological_process": "GO:0001525 angiogenesis;GO:0006596 polyamine biosynthetic process;GO:0009447 putrescine catabolic process;GO:0032918 spermidine acetylation;GO:0006595 polyamine metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q3T0Q0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3T057-1", "uniprot_id": "RL23_BOVIN", "mass": 14865.0, "length": 140, "protein_name": "Large ribosomal subunit protein uL14", "gene_name": "RPL23", "organism": "Bovine", "refseq_name": "large ribosomal subunit protein uL14", "refseq_ac": "NP_001030186", "gene_names_uniprotkb": "RPL23", "gene_names_refseq": "RPL23", "protein_names_uniprotkb": "Large ribosomal subunit protein uL14; 60S ribosomal protein L23", "protein_names_refseq": "60S ribosomal protein L23; large ribosomal subunit protein uL14", "tax_id": 9913, "disease": "", "pathway": " (bta:504876); (R-BTA-156827); (R-BTA-1799339); (R-BTA-6791226); (R-BTA-72689); (R-BTA-72706); (R-BTA-975956); (R-BTA-975957); (R-BTA-9954709); (R-BTA-9954714); (R-BTA-9954716)", "pathway_count": 11, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A6QLM2", "ec_number_list": "", "go_molecular_function": "GO:0031625 ubiquitin protein ligase binding;GO:0001223 transcription coactivator binding;GO:1990948 ubiquitin ligase inhibitor activity;GO:0003735 structural constituent of ribosome;GO:0070180 large ribosomal subunit rRNA binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0045202 synapse;GO:0022625 cytosolic large ribosomal subunit;GO:0015934 large ribosomal subunit", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0008284 positive regulation of cell population proliferation;GO:0050821 protein stabilization;GO:1901798 positive regulation of signal transduction by p53 class mediator;GO:2000059 negative regulation of ubiquitin-dependent protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q3T057-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q5EA28-1", "uniprot_id": "CXXC1_BOVIN", "mass": 75870.0, "length": 658, "protein_name": "CXXC-type zinc finger protein 1", "gene_name": "CXXC1", "organism": "Bovine", "refseq_name": "CXXC-type zinc finger protein 1", "refseq_ac": "NP_001019688", "gene_names_uniprotkb": "CXXC1", "gene_names_refseq": "CXXC1", "protein_names_uniprotkb": "CXXC-type zinc finger protein 1; CpG-binding protein; PHD finger and CXXC domain-containing protein 1", "protein_names_refseq": "CXXC finger 1 (PHD domain); CXXC-type zinc finger protein 1; PHD finger and CXXC domain-containing protein 1; cpG-binding protein", "tax_id": 9913, "disease": "", "pathway": " (bta:511446); (R-BTA-9772755)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "Transcriptional activator that exhibits a unique DNA binding specificity for CpG unmethylated motifs with a preference for CpGG., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0045322 unmethylated CpG binding;GO:0140002 histone H3K4me3 reader activity;GO:0003677 DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0016607 nuclear speck;GO:0016363 nuclear matrix;GO:0048188 Set1C/COMPASS complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045893 positive regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q5EA28-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3ZBE5-1", "uniprot_id": "SLU7_BOVIN", "mass": 68203.0, "length": 586, "protein_name": "Pre-mRNA-splicing factor SLU7", "gene_name": "SLU7", "organism": "Bovine", "refseq_name": "pre-mRNA-splicing factor SLU7", "refseq_ac": "NP_001160089", "gene_names_uniprotkb": "SLU7", "gene_names_refseq": "SLU7", "protein_names_uniprotkb": "Pre-mRNA-splicing factor SLU7", "protein_names_refseq": "SLU7 splicing factor homolog; pre-mRNA-splicing factor SLU7", "tax_id": 9913, "disease": "", "pathway": " (bta:512318); (R-BTA-159236); (R-BTA-72163)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Involved in pre-mRNA splicing., [UniProtKB, UniProtKB]; Required for pre-mRNA splicing as component of the spliceosome. Participates in the second catalytic step of pre-mRNA splicing, when the free hydroxyl group of exon I attacks the 3'-splice site to generate spliced mRNA and the excised lariat intron. Required for holding exon 1 properly in the spliceosome and for correct AG identification when more than one possible AG exists in 3'-splicing site region. May be involved in the activation of proximal AG. Probably also involved in alternative splicing regulation., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0030628 pre-mRNA 3'-splice site binding;GO:0000386 second spliceosomal transesterification activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0016607 nuclear speck;GO:0005681 spliceosomal complex;GO:0071013 catalytic step 2 spliceosome", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0034605 cellular response to heat;GO:0045292 mRNA cis splicing, via spliceosome;GO:0000380 alternative mRNA splicing, via spliceosome;GO:0000389 mRNA 3'-splice site recognition", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q3ZBE5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3T116-1", "uniprot_id": "ICT1_BOVIN", "mass": 23307.0, "length": 206, "protein_name": "Large ribosomal subunit protein mL62", "gene_name": "MRPL58", "organism": "Bovine", "refseq_name": "large ribosomal subunit protein mL62 precursor", "refseq_ac": "NP_001029665", "gene_names_uniprotkb": "MRPL58; ICT1", "gene_names_refseq": "ICT1; MRP-L58; MRPL58", "protein_names_uniprotkb": "Large ribosomal subunit protein mL62; 3.1.1.29; 39S ribosomal protein L58, mitochondrial; Immature colon carcinoma transcript 1 protein homolog; MRP-L58; Peptidyl-tRNA hydrolase ICT1, mitochondrial", "protein_names_refseq": "39S ribosomal protein L58, mitochondrial; immature colon carcinoma transcript 1 protein homolog; large ribosomal subunit protein mL62 precursor; large ribosomal subunit protein mL62; peptidyl-tRNA hydrolase ICT1, mitochondrial", "tax_id": 9913, "disease": "", "pathway": " (bta:515465); (R-BTA-5389840); (R-BTA-5419276); (R-BTA-9937383)", "pathway_count": 4, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A7YWR4", "ec_number_list": "3.1.1.29;3.6.5.-;7.1.1.2;3.6.5.3;7.1.1.9", "go_molecular_function": "GO:0004045 peptidyl-tRNA hydrolase activity;GO:0016150 translation release factor activity, codon nonspecific", "go_cellular_component": "GO:0005762 mitochondrial large ribosomal subunit;GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0070126 mitochondrial translational termination", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q3T116-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3T0E1-1", "uniprot_id": "EXOS3_BOVIN", "mass": 29495.0, "length": 275, "protein_name": "Exosome complex component RRP40", "gene_name": "EXOSC3", "organism": "Bovine", "refseq_name": "exosome complex component RRP40", "refseq_ac": "NP_001030474", "gene_names_uniprotkb": "EXOSC3; RRP40", "gene_names_refseq": "EXOSC3", "protein_names_uniprotkb": "Exosome complex component RRP40; Exosome component 3; Ribosomal RNA-processing protein 40", "protein_names_refseq": "exosome complex component RRP40; exosome complex exonuclease RRP40; ribosomal RNA-processing protein 40", "tax_id": 9913, "disease": "", "pathway": " (bta:533245); (R-BTA-429958); (R-BTA-450385); (R-BTA-450513); (R-BTA-450604); (R-BTA-6791226); (R-BTA-9930044)", "pathway_count": 7, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. The RNA exosome may be involved in Ig class switch recombination (CSR) and/or Ig variable region somatic hypermutation (SHM) by targeting AICDA deamination activity to transcribed dsDNA substrates. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA. The catalytic inactive RNA exosome core complex of 9 subunits (Exo-9) is proposed to play a pivotal role in the binding and presentation of RNA for ribonucleolysis, and to serve as a scaffold for the association with catalytic subunits and accessory proteins or complexes. EXOSC3 as peripheral part of the Exo-9 complex stabilizes the hexameric ring of RNase PH-domain subunits through contacts with EXOSC9 and EXOSC5 (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005829 cytosol;GO:0000791 euchromatin;GO:0000176 nuclear exosome (RNase complex)", "go_biological_process": "GO:0000956 nuclear-transcribed mRNA catabolic process;GO:0045190 isotype switching;GO:0000467 exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0034475 U4 snRNA 3'-end processing;GO:0045006 DNA deamination", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q3T0E1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q4TZY1-1", "uniprot_id": "KCJ12_BOVIN", "mass": 48442.0, "length": 427, "protein_name": "ATP-sensitive inward rectifier potassium channel 12", "gene_name": "KCNJ12", "organism": "Bovine", "refseq_name": "ATP-sensitive inward rectifier potassium channel 12 isoform X1", "refseq_ac": "XP_005220652", "gene_names_uniprotkb": "KCNJ12", "gene_names_refseq": "IRK2; KCNJ12; KIR2.2", "protein_names_uniprotkb": "ATP-sensitive inward rectifier potassium channel 12; Potassium channel, inwardly rectifying subfamily J member 12", "protein_names_refseq": "ATP-sensitive inward rectifier potassium channel 12 isoform X1", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-1296041); (R-BTA-1296053); (R-BTA-5576886); (R-BTA-997272)", "pathway_count": 4, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Inward rectifying potassium channel that probably participates in controlling the resting membrane potential in electrically excitable cells. Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.8.-.-", "go_molecular_function": "GO:0046872 metal ion binding;GO:0005242 inward rectifier potassium channel activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane;GO:0034702 monoatomic ion channel complex", "go_biological_process": "GO:0051289 protein homotetramerization;GO:0006813 potassium ion transport;GO:1990573 potassium ion import across plasma membrane", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q4TZY1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3ZC50-1", "uniprot_id": "CCD47_BOVIN", "mass": 55742.0, "length": 483, "protein_name": "PAT complex subunit CCDC47", "gene_name": "CCDC47", "organism": "Bovine", "refseq_name": "PAT complex subunit CCDC47 precursor", "refseq_ac": "NP_001030505", "gene_names_uniprotkb": "CCDC47", "gene_names_refseq": "CCDC47", "protein_names_uniprotkb": "PAT complex subunit CCDC47; Coiled-coil domain-containing protein 47", "protein_names_refseq": "PAT complex subunit CCDC47 precursor; PAT complex subunit CCDC47; coiled-coil domain-containing protein 47", "tax_id": 9913, "disease": "", "pathway": " (bta:540167)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "Component of the multi-pass translocon (MPT) complex that mediates insertion of multi-pass membrane proteins into the lipid bilayer of membranes. The MPT complex takes over after the SEC61 complex: following membrane insertion of the first few transmembrane segments of proteins by the SEC61 complex, the MPT complex occludes the lateral gate of the SEC61 complex to promote insertion of subsequent transmembrane regions (By similarity). Within the MPT complex, the PAT subcomplex sequesters any highly polar regions in the transmembrane domains away from the non-polar membrane environment until they can be buried in the interior of the fully assembled protein. Within the PAT subcomplex, CCDC47 occludes the lateral gate of the SEC61 complex (By similarity). Involved in the regulation of calcium ion homeostasis in the ER. Required for proper protein degradation via the ERAD (ER-associated degradation) pathway (By similarity). Has an essential role in the maintenance of ER organization during embryogenesis (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A5D9E2", "ec_number_list": "", "go_molecular_function": "GO:0005509 calcium ion binding;GO:0043022 ribosome binding;GO:0044183 protein folding chaperone", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane;GO:0030867 rough endoplasmic reticulum membrane;GO:0160064 multi-pass translocon complex", "go_biological_process": "GO:0045048 protein insertion into ER membrane;GO:0036503 ERAD pathway;GO:0032469 endoplasmic reticulum calcium ion homeostasis;GO:0160063 multi-pass transmembrane protein insertion into ER membrane", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q3ZC50-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q8SPU7-1", "uniprot_id": "ACHA5_BOVIN", "mass": 54260.0, "length": 475, "protein_name": "Neuronal acetylcholine receptor subunit alpha-5", "gene_name": "CHRNA5", "organism": "Bovine", "refseq_name": "neuronal acetylcholine receptor subunit alpha-5 precursor", "refseq_ac": "NP_776939", "gene_names_uniprotkb": "CHRNA5", "gene_names_refseq": "CHRNA5", "protein_names_uniprotkb": "Neuronal acetylcholine receptor subunit alpha-5", "protein_names_refseq": "cholinergic receptor, nicotinic, alpha 5 (neuronal); cholinergic receptor, nicotinic, alpha polypeptide 5; neuronal acetylcholine receptor subunit alpha-5 precursor; neuronal acetylcholine receptor subunit alpha-5", "tax_id": 9913, "disease": "", "pathway": " (bta:282177); (R-BTA-629594); (R-BTA-629597)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "9003033", "class_list": "", "function": "Component of neuronal acetylcholine receptors (nAChRs) that function as pentameric, ligand-gated cation channels with high calcium permeability among other activities. nAChRs are excitatory neurotrasnmitter receptors formed by a collection of nAChR subunits known to mediate synaptic transmission in the nervous system and the neuromuscular junction. Each nAchR subunit confers differential attributes to channel properties, including activation, deactivation and desensitization kinetics, pH sensitivity, cation permeability, and binding to allosteric modulators. Has an accessory rather than functional role and is only able to form functional nAChRs when co-assembled with another beta subunit. Participates in pentameric assemblies along with CHRNA3, CHRNA4, CHRNB2 and CHRNB4. Increases receptor sensitivity to acetylcholine and nicotine when associated with CHRNA4 and CHRNB2. Plays a role in nicotine addiction., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.11.1;1.8.-.-", "go_molecular_function": "GO:0015464 acetylcholine receptor activity;GO:0022848 acetylcholine-gated monoatomic cation-selective channel activity;GO:0004888 transmembrane signaling receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005892 acetylcholine-gated channel complex;GO:0045202 synapse;GO:0045211 postsynaptic membrane;GO:0043005 neuron projection", "go_biological_process": "GO:0007271 synaptic transmission, cholinergic;GO:0007274 neuromuscular synaptic transmission;GO:0035094 response to nicotine;GO:0035095 behavioral response to nicotine;GO:0095500 acetylcholine receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q8SPU7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3ZBI5-1", "uniprot_id": "LRC33_BOVIN", "mass": 76520.0, "length": 692, "protein_name": "Transforming growth factor beta activator LRRC33", "gene_name": "NRROS", "organism": "Bovine", "refseq_name": "transforming growth factor beta activator LRRC33 precursor", "refseq_ac": "NP_001029563", "gene_names_uniprotkb": "NRROS; LRRC33", "gene_names_refseq": "LRRC33; NRROS; UNQ3030", "protein_names_uniprotkb": "Transforming growth factor beta activator LRRC33; Leucine-rich repeat-containing protein 33; Negative regulator of reactive oxygen species", "protein_names_refseq": "ELLP3030; leucine rich repeat containing 33; leucine-rich repeat-containing protein 33; transforming growth factor beta activator LRRC33 precursor; transforming growth factor beta activator LRRC33", "tax_id": 9913, "disease": "", "pathway": " (bta:510688)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "Key regulator of transforming growth factor beta-1 (TGFB1) specifically required for microglia function in the nervous system. Required for activation of latent TGF-beta-1 in macrophages and microglia: associates specifically via disulfide bonds with the Latency-associated peptide (LAP), which is the regulatory chain of TGFB1, and regulates integrin-dependent activation of TGF-beta-1. TGF-beta-1 activation mediated by LRRC33/NRROS is highly localized: there is little spreading of TGF-beta-1 activated from one microglial cell to neighboring microglia, suggesting the existence of localized and selective activation of TGF-beta-1 by LRRC33/NRROS. Indirectly plays a role in Toll-like receptor (TLR) signaling: ability to inhibit TLR-mediated NF-kappa-B activation and cytokine production is probably a consequence of its role in TGF-beta-1 signaling., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 10, "predicted_n_glycosites": 9, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 10, "binding_glycan_count": 0, "secondary_ac_list": "Q5BIS4", "ec_number_list": "", "go_molecular_function": "GO:0019838 growth factor binding;GO:0141069 receptor ligand inhibitor activity;GO:0050431 transforming growth factor beta binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0005783 endoplasmic reticulum;GO:0005886 plasma membrane;GO:0009986 cell surface;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0035583 sequestering of TGFbeta in extracellular matrix;GO:0006954 inflammatory response;GO:0006955 immune response;GO:0014005 microglia development;GO:0007616 long-term memory", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q3ZBI5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3T046-1", "uniprot_id": "DHRS6_BOVIN", "mass": 26662.0, "length": 245, "protein_name": "Dehydrogenase/reductase SDR family member 6", "gene_name": "BDH2", "organism": "Bovine", "refseq_name": "dehydrogenase/reductase SDR family member 6", "refseq_ac": "NP_001029660", "gene_names_uniprotkb": "BDH2; DHRS6", "gene_names_refseq": "BDH2; DHRS6", "protein_names_uniprotkb": "Dehydrogenase/reductase SDR family member 6; (R)-beta-hydroxybutyrate dehydrogenase; 1.1.1.-; 1.1.1.104; 1.1.1.30; 3-hydroxybutyrate dehydrogenase type 2; 4-oxo-L-proline reductase; Oxidoreductase UCPA; Short chain dehydrogenase/reductase family 15C member 1", "protein_names_refseq": "(R)-beta-hydroxybutyrate dehydrogenase; 3-hydroxybutyrate dehydrogenase, type 2; 4-oxo-L-proline reductase; R-beta-hydroxybutyrate dehydrogenase; dehydrogenase/reductase (SDR family) member 6; dehydrogenase/reductase SDR family member 6; oxidoreductase UCPA; short chain dehydrogenase/reductase family 15C member 1", "tax_id": 9913, "disease": "", "pathway": " (bta:515321)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "NAD(H)-dependent dehydrogenase/reductase with a preference for cyclic substrates (By similarity). Catalyzes stereoselective conversion of 4-oxo-L-proline to cis-4-hydroxy-L-proline, likely a detoxification mechanism for ketoprolines (By similarity). Mediates the formation of 2,5-dihydroxybenzoate (2,5-DHBA), a siderophore that chelates free cytoplasmic iron and associates with LCN2, thereby regulating iron transport and homeostasis while protecting cells against free radical-induced oxidative stress. The iron-siderophore complex is imported into mitochondria, providing an iron source for mitochondrial metabolic processes in particular heme synthesis (By similarity). May act as a 3-hydroxybutyrate dehydrogenase (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.1.1.30;1.1.1.104;1.1.1.-", "go_molecular_function": "GO:0003858 3-hydroxybutyrate dehydrogenase activity;GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor;GO:0016617 4-oxoproline reductase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0006629 lipid metabolic process;GO:0019290 siderophore biosynthetic process;GO:0042168 heme metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q3T046-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3T095-1", "uniprot_id": "ING4_BOVIN", "mass": 28429.0, "length": 248, "protein_name": "Inhibitor of growth protein 4", "gene_name": "ING4", "organism": "Bovine", "refseq_name": "inhibitor of growth protein 4", "refseq_ac": "NP_001030466", "gene_names_uniprotkb": "ING4", "gene_names_refseq": "ING4", "protein_names_uniprotkb": "Inhibitor of growth protein 4; p29ING4", "protein_names_refseq": "inhibitor of growth protein 4; p29ING4", "tax_id": 9913, "disease": "", "pathway": " (bta:532483)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of HBO1 complexes, which specifically mediate acetylation of histone H3 at 'Lys-14' (H3K14ac), and have reduced activity toward histone H4. Through chromatin acetylation it may function in DNA replication. May inhibit tumor progression by modulating the transcriptional output of signaling pathways which regulate cell proliferation. Can suppress brain tumor angiogenesis through transcriptional repression of RELA/NFKB3 target genes when complexed with RELA. May also specifically suppress loss of contact inhibition elicited by activated oncogenes such as MYC. Represses hypoxia inducible factor's (HIF) activity by interacting with HIF prolyl hydroxylase 2 (EGLN1) (By similarity). Can enhance apoptosis induced by serum starvation in mammary epithelial cell line HC11 (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003713 transcription coactivator activity;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005634 nucleus;GO:0000123 histone acetyltransferase complex", "go_biological_process": "GO:0006338 chromatin remodeling;GO:0043065 positive regulation of apoptotic process;GO:0006355 regulation of DNA-templated transcription;GO:0006915 apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q3T095-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3T0A3-1", "uniprot_id": "CFAD_BOVIN", "mass": 27878.0, "length": 259, "protein_name": "Complement factor D", "gene_name": "CFD", "organism": "Bovine", "refseq_name": "complement factor D precursor", "refseq_ac": "NP_001029427", "gene_names_uniprotkb": "CFD", "gene_names_refseq": "CFD; DF", "protein_names_uniprotkb": "Complement factor D; 3.4.21.46; Adipsin; C3 convertase activator; Properdin factor D", "protein_names_refseq": "C3 convertase activator; D component of complement (adipsin); complement factor D precursor; properdin factor D", "tax_id": 9913, "disease": "", "pathway": " (bta:505647); (R-BTA-114608); (R-BTA-173736); (R-BTA-6798695)", "pathway_count": 4, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Serine protease that initiates the alternative pathway of the complement system, a cascade of proteins that leads to phagocytosis and breakdown of pathogens and signaling that strengthens the adaptive immune system. In contrast to other complement pathways (classical, lectin and GZMK) that are directly activated by pathogens or antigen-antibody complexes, the alternative complement pathway is initiated by the spontaneous hydrolysis of complement C3. The alternative complement pathway acts as an amplification loop that enhances complement activation by mediating the formation of C3 and C5 convertases. Activated CFD cleaves factor B (CFB) when the latter is complexed with complement C3b, activating the C3 convertase of the alternative pathway., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.1.1.42;2.5.1.18;2.7.1.1;2.7.11.24;3.2.1.23;2.4.2.1;5.2.1.8;4.1.2.13;3.6.1.6;2.3.2.27;3.1.6.14;3.6.4.13;1.1.1.205;2.7.1.11;3.4.21.7;2.7.11.22;2.7.11.23;2.3.2.26;2.4.1.25;3.2.1.33;4.2.99.18;5.6.2.4;3.6.4.12;3.4.23.5;1.13.11.34;1.13.11.12;2.3.2.13;3.6.4.6;1.16.3.1;1.11.1.6;3.4.18.1;3.4.22.1;3.6.4.10;3.4.22.27;3.4.24.35;3.6.5.-;3.1.1.47;5.3.2.1;5.3.3.12;3.4.19.1;3.4.21.47;2.7.1.35;1.8.3.5;2.4.1.1;3.5.1.23;3.5.1.-;3.4.22.52;2.3.3.8;5.4.2.11;5.4.2.4;3.3.2.6;3.4.11.4;3.4.21.46;2.7.4.6;2.7.13.3;4.1.2.4;5.3.1.9;5.1.3.-;3.6.1.-;2.4.2.7;4.2.1.24", "go_molecular_function": "GO:0004252 serine-type endopeptidase activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0051604 protein maturation;GO:0031638 zymogen activation;GO:0006957 complement activation, alternative pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q3T0A3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3T0D7-1", "uniprot_id": "SAR1A_BOVIN", "mass": 22409.0, "length": 198, "protein_name": "Small COPII coat GTPase SAR1A", "gene_name": "SAR1A", "organism": "Bovine", "refseq_name": "small COPII coat GTPase SAR1A", "refseq_ac": "NP_001029693", "gene_names_uniprotkb": "SAR1A", "gene_names_refseq": "SAR1A", "protein_names_uniprotkb": "Small COPII coat GTPase SAR1A; 3.6.5.2", "protein_names_refseq": "GTP-binding protein SAR1a; SAR1 gene homolog A; SAR1 homolog A; small COPII coat GTPase SAR1A", "tax_id": 9913, "disease": "", "pathway": " (bta:517171)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Small GTPase that cycles between an active GTP-bound and an inactive GDP-bound state and mainly functions in vesicle-mediated endoplasmic reticulum (ER) to Golgi transport. The active GTP-bound form inserts into the endoplasmic reticulum membrane where it recruits the remainder of the coat protein complex II/COPII. The coat protein complex II assembling and polymerizing on endoplasmic reticulum membrane is responsible for both the sorting of cargos and the deformation and budding of membranes into vesicles destined to the Golgi. The GTPase activity of SAR1 by controlling the timing of COPII budding regulates the size of the formed vesicles and is important for cargo selection depending on their size. Together with SEC16A, forms the organized scaffold defining endoplasmic reticulum exit sites (ERES), some specific domains of the endoplasmic reticulum where COPII vesicles form. In addition to its role in vesicle trafficking, can also function as a leucine sensor regulating TORC1 signaling and more indirectly cellular metabolism, growth and survival. In absence of leucine, interacts with the GATOR2 complex via MIOS and inhibits TORC1 signaling. The binding of leucine abrogates the interaction with GATOR2 and the inhibition of the TORC1 signaling. This function is completely independent of the GTPase activity of SAR1B., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.6.5.2;3.6.5.5;3.6.5.-;3.6.5.3;2.7.11.1;3.6.1.5;3.6.1.15;3.6.5.4", "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0046872 metal ion binding;GO:0003925 G protein activity;GO:0140785 amino acid sensor activity", "go_cellular_component": "GO:0005829 cytosol;GO:0005765 lysosomal membrane;GO:0005789 endoplasmic reticulum membrane;GO:0032580 Golgi cisterna membrane;GO:0070971 endoplasmic reticulum exit site", "go_biological_process": "GO:0090110 COPII-coated vesicle cargo loading;GO:0006886 intracellular protein transport;GO:0061024 membrane organization;GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0048208 COPII vesicle coating", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q3T0D7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3T0G8-1", "uniprot_id": "SYUA_BOVIN", "mass": 14508.0, "length": 140, "protein_name": "Alpha-synuclein", "gene_name": "SNCA", "organism": "Bovine", "refseq_name": "alpha-synuclein", "refseq_ac": "NP_001029213", "gene_names_uniprotkb": "SNCA", "gene_names_refseq": "SNCA", "protein_names_uniprotkb": "Alpha-synuclein", "protein_names_refseq": "alpha-synuclein; synuclein, alpha (non A4 component of amyloid precursor)", "tax_id": 9913, "disease": "", "pathway": " (bta:282857); (R-BTA-9833482)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "12932858;21953452;30711526", "class_list": "", "function": "Analysis of membrane curvature sensing by amphipathic helices using alpha-synuclein and annexin B12 [ANXB12], [RefSeq, PubMed]; Immunocytochemistry shows alpha synuclein localized to the Golgi apparatus and vesicles of bovine adrenal medullary chromaffin cells, consistent with its putative role in vesicular function within synapses., [RefSeq, PubMed]; Neuronal protein that plays several roles in synaptic activity such as regulation of synaptic vesicle trafficking and subsequent neurotransmitter release (By similarity). Participates as a monomer in synaptic vesicle exocytosis by enhancing vesicle priming, fusion and dilation of exocytotic fusion pores (By similarity). Mechanistically, acts by increasing local Ca(2+) release from microdomains which is essential for the enhancement of ATP-induced exocytosis (By similarity). Also acts as a molecular chaperone in its multimeric membrane-bound state, assisting in the folding of synaptic fusion components called SNAREs (Soluble NSF Attachment Protein REceptors) at presynaptic plasma membrane in conjunction with cysteine string protein-alpha/DNAJC5 (By similarity). This chaperone activity is important to sustain normal SNARE-complex assembly during aging (By similarity). Also plays a role in the regulation of the dopamine neurotransmission by associating with the dopamine transporter (DAT1) and thereby modulating its activity (By similarity)., [UniProtKB, UniProtKB]; Overexpression of alpha-synuclein but not beta-synuclein quickened the post- fusion discharge of BDNF-pHluorin by approxinately 30%. However, neither alpha- nor beta-synuclein significantly altered curvature dynamics associated with fusion pore expansion., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0042802 identical protein binding;GO:0005507 copper ion binding;GO:1903136 cuprous ion binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0016020 membrane", "go_biological_process": "GO:0050808 synapse organization;GO:0001963 synaptic transmission, dopaminergic;GO:0014059 regulation of dopamine secretion;GO:0016082 synaptic vesicle priming;GO:0048488 synaptic vesicle endocytosis", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q3T0G8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3T0I4-1", "uniprot_id": "THOC4_BOVIN", "mass": 26953.0, "length": 257, "protein_name": "THO complex subunit 4", "gene_name": "ALYREF", "organism": "Bovine", "refseq_name": "THO complex subunit 4", "refseq_ac": "NP_001030494", "gene_names_uniprotkb": "ALYREF; ALY; BEF; THOC4", "gene_names_refseq": "ALYREF; THOC4", "protein_names_uniprotkb": "THO complex subunit 4; Ally of AML-1 and LEF-1; Aly/REF export factor; Tho4; Transcriptional coactivator Aly/REF; bZIP-enhancing factor BEF", "protein_names_refseq": "THO complex 4; THO complex subunit 4; ally of AML-1 and LEF-1; bZIP-enhancing factor BEF; tho4; transcriptional coactivator Aly/REF", "tax_id": 9913, "disease": "", "pathway": " (bta:537706); (R-BTA-159227); (R-BTA-159230); (R-BTA-159231); (R-BTA-159236); (R-BTA-72163)", "pathway_count": 6, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Functions as an mRNA export adapter; component of the transcription/export (TREX) complex which is thought to couple mRNA transcription, processing and nuclear export, and specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NXF1 pathway. Involved in the nuclear export of intronless mRNA; proposed to be recruited to intronless mRNA by ATP-bound DDX39B. Plays a key role in mRNP recognition and mRNA packaging by bridging the mRNP-bound EJC and the TREX core complex. TREX recruitment occurs via an interaction between ALYREF/THOC4 and the cap-binding protein NCBP1. Required for TREX complex assembly and for linking DDX39B to the cap-binding complex (CBC). Binds mRNA which is thought to be transferred to the NXF1-NXT1 heterodimer for export (TAP/NXF1 pathway). In conjunction with THOC5 functions in NXF1-NXT1 mediated nuclear export of HSP70 mRNA; both proteins enhance the RNA binding activity of NXF1 and are required for NXF1 localization to the nuclear rim. Involved in mRNA export of C5-methylcytosine (m5C)-containing mRNAs: specifically recognizes and binds m5C mRNAs and mediates their nucleo-cytoplasmic shuttling. Acts as a chaperone and promotes the dimerization of transcription factors containing basic leucine zipper (bZIP) domains and thereby promotes transcriptional activation. Involved in transcription elongation and genome stability., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003729 mRNA binding;GO:0062153 C5-methylcytidine-containing RNA reader activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0016607 nuclear speck;GO:0005681 spliceosomal complex", "go_biological_process": "GO:0006397 mRNA processing;GO:0006406 mRNA export from nucleus;GO:0008380 RNA splicing;GO:0006405 RNA export from nucleus", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q3T0I4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3T0N5-1", "uniprot_id": "MK13_BOVIN", "mass": 42229.0, "length": 366, "protein_name": "Mitogen-activated protein kinase 13", "gene_name": "MAPK13", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "MAPK13", "gene_names_refseq": "", "protein_names_uniprotkb": "Mitogen-activated protein kinase 13; 2.7.11.24; MAP kinase 13; MAPK 13", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK13 is one of the four p38 MAPKs which play an important role in the cascades of cellular responses evoked by extracellular stimuli such as pro-inflammatory cytokines or physical stress leading to direct activation of transcription factors such as ELK1 and ATF2. Accordingly, p38 MAPKs phosphorylate a broad range of proteins and it has been estimated that they may have approximately 200 to 300 substrates each. MAPK13 is one of the less studied p38 MAPK isoforms. Some of the targets are downstream kinases such as MAPKAPK2, which are activated through phosphorylation and further phosphorylate additional targets. Plays a role in the regulation of protein translation by phosphorylating and inactivating EEF2K. Involved in cytoskeletal remodeling through phosphorylation of MAPT and STMN1. Mediates UV irradiation induced up-regulation of the gene expression of CXCL14. Plays an important role in the regulation of epidermal keratinocyte differentiation, apoptosis and skin tumor development. Phosphorylates the transcriptional activator MYB in response to stress which leads to rapid MYB degradation via a proteasome-dependent pathway. MAPK13 also phosphorylates and down-regulates PRKD1 during regulation of insulin secretion in pancreatic beta cells (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.11.1;2.7.11.25;2.7.11.24;2.7.11.22;2.7.11.13;2.7.11.23;2.7.12.1;2.7.12.2;2.7.11.17;2.7.11.39;2.7.10.2;2.7.1.150;2.7.11.12;2.7.11.31;2.7.11.26;2.7.11.21;2.7.1.153;2.7.1.137;2.7.1.154;4.1.1.32;2.7.11.38;2.7.11.11;3.1.11.-;2.7.4.6;2.7.13.3;2.7.4.18;3.1.24.-;2.7.11.-;2.7.11.4;2.7.2.3;2.7.11.10", "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0004707 MAP kinase activity;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0035556 intracellular signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q3T0N5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3T0P7-1", "uniprot_id": "ITM2B_BOVIN", "mass": 30400.0, "length": 266, "protein_name": "Integral membrane protein 2B", "gene_name": "ITM2B", "organism": "Bovine", "refseq_name": "integral membrane protein 2B", "refseq_ac": "NP_001030265", "gene_names_uniprotkb": "ITM2B", "gene_names_refseq": "Bri; ITM2B; imBRI2", "protein_names_uniprotkb": "Integral membrane protein 2B; ABri23; Bri; C-terminal peptide; Immature BRI2; Mature BRI2; P23 peptide; Transmembrane protein BRI; imBRI2; mBRI2", "protein_names_refseq": "immature BRI2; integral membrane protein 2B; transmembrane protein BRI", "tax_id": 9913, "disease": "", "pathway": " (bta:510575)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Bri23 peptide prevents aggregation of APP amyloid-beta protein 42 into toxic oligomers., [UniProtKB]; Mature BRI2 (mBRI2) functions as a modulator of the amyloid-beta A4 precursor protein (APP) processing leading to a strong reduction in the secretion of secretase-processed amyloid-beta protein 40 and amyloid-beta protein 42., [UniProtKB]; Plays a regulatory role in the processing of the amyloid-beta A4 precursor protein (APP) and acts as an inhibitor of the amyloid-beta peptide aggregation and fibrils deposition. Plays a role in the induction of neurite outgrowth. Functions as a protease inhibitor by blocking access of secretases to APP cleavage sites (By similarity)., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0001540 amyloid-beta binding", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005615 extracellular space;GO:0005794 Golgi apparatus;GO:0005886 plasma membrane;GO:0010008 endosome membrane", "go_biological_process": "GO:0042985 negative regulation of amyloid precursor protein biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q3T0P7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3T0Q3-1", "uniprot_id": "RPB3_BOVIN", "mass": 31429.0, "length": 275, "protein_name": "DNA-directed RNA polymerase II subunit RPB3", "gene_name": "POLR2C", "organism": "Bovine", "refseq_name": "DNA-directed RNA polymerase II subunit RPB3", "refseq_ac": "NP_001029384", "gene_names_uniprotkb": "POLR2C", "gene_names_refseq": "POLR2C", "protein_names_uniprotkb": "DNA-directed RNA polymerase II subunit RPB3; DNA-directed RNA polymerase II subunit C; RNA polymerase II subunit 3; RNA polymerase II subunit B3", "protein_names_refseq": "DNA directed RNA polymerase II polypeptide C; DNA-directed RNA polymerase II subunit C; DNA-directed RNA polymerase II subunit RPB3; RNA polymerase II subunit 3; RNA polymerase II subunit B3; polymerase (RNA) II (DNA directed) polypeptide C, 33kDa", "tax_id": 9913, "disease": "", "pathway": " (bta:504452); (R-BTA-112382); (R-BTA-113418); (R-BTA-5578749); (R-BTA-674695); (R-BTA-6781823); (R-BTA-6782135); (R-BTA-6782210); (R-BTA-6796648); (R-BTA-6803529); (R-BTA-6807505); (R-BTA-72086); (R-BTA-72163); (R-BTA-72165); (R-BTA-72203); (R-BTA-73776); (R-BTA-73779); (R-BTA-75953); (R-BTA-75955); (R-BTA-76042); (R-BTA-77075); (R-BTA-9018519); (R-BTA-9770562)", "pathway_count": 23, "publication_count": 4, "publication_id_list": "16305752;16769904;26789250;28892040", "class_list": "", "function": "Core component of RNA polymerase II (Pol II), a DNA-dependent RNA polymerase which synthesizes mRNA precursors and many functional non-coding RNAs using the four ribonucleoside triphosphates as substrates., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A7E3Q9", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0046983 protein dimerization activity;GO:0003899 DNA-directed RNA polymerase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005665 RNA polymerase II, core complex", "go_biological_process": "GO:0006366 transcription by RNA polymerase II;GO:0006367 transcription initiation at RNA polymerase II promoter;GO:0006368 transcription elongation by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q3T0Q3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3T0S5-1", "uniprot_id": "ALDOB_BOVIN", "mass": 39543.0, "length": 364, "protein_name": "Fructose-bisphosphate aldolase B", "gene_name": "ALDOB", "organism": "Bovine", "refseq_name": "fructose-bisphosphate aldolase B", "refseq_ac": "NP_001029657", "gene_names_uniprotkb": "ALDOB", "gene_names_refseq": "ALDOB", "protein_names_uniprotkb": "Fructose-bisphosphate aldolase B; 4.1.2.13; Liver-type aldolase", "protein_names_refseq": "aldolase B, fructose-bisphosphate; fructose-bisphosphate aldolase B; liver-type aldolase", "tax_id": 9913, "disease": "", "pathway": " (bta:515263)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalyzes the aldol cleavage of fructose 1,6-biphosphate to form two triosephosphates dihydroxyacetone phosphate and D-glyceraldehyde 3-phosphate in glycolysis as well as the reverse stereospecific aldol addition reaction in gluconeogenesis. In fructolysis, metabolizes fructose 1-phosphate derived from the phosphorylation of dietary fructose by fructokinase into dihydroxyacetone phosphate and D-glyceraldehyde (By similarity). Acts as an adapter independently of its enzymatic activity, exerts a tumor suppressor role by stabilizing the ternary complex with G6PD and TP53 to inhibit G6PD activity and keep oxidative pentose phosphate metabolism in check (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 9, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "4.1.2.13", "go_molecular_function": "GO:0004332 fructose-bisphosphate aldolase activity;GO:0061609 fructose-1-phosphate aldolase activity", "go_cellular_component": "GO:0005829 cytosol;GO:0034451 centriolar satellite", "go_biological_process": "GO:0006094 gluconeogenesis;GO:0006000 fructose metabolic process;GO:0006096 glycolytic process;GO:0030388 fructose 1,6-bisphosphate metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q3T0S5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3T0T1-1", "uniprot_id": "PSB10_BOVIN", "mass": 29099.0, "length": 273, "protein_name": "Proteasome subunit beta type-10", "gene_name": "PSMB10", "organism": "Bovine", "refseq_name": "proteasome subunit beta type-10", "refseq_ac": "NP_001029212", "gene_names_uniprotkb": "PSMB10", "gene_names_refseq": "PSMB10", "protein_names_uniprotkb": "Proteasome subunit beta type-10; 3.4.25.1; Proteasome subunit beta-2i", "protein_names_refseq": "proteasome (prosome, macropain) subunit, beta type, 10; proteasome subunit beta 10; proteasome subunit beta type-10; proteasome subunit beta-2i", "tax_id": 9913, "disease": "", "pathway": " (bta:282328); (R-BTA-1236974); (R-BTA-1236978); (R-BTA-9907900); (R-BTA-9912633)", "pathway_count": 5, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit is involved in antigen processing to generate class I binding peptides (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.4.25.1", "go_molecular_function": "GO:0004175 endopeptidase activity;GO:0004298 threonine-type endopeptidase activity", "go_cellular_component": "GO:0019774 proteasome core complex, beta-subunit complex;GO:1990111 spermatoproteasome complex;GO:0005634 nucleus;GO:0005829 cytosol;GO:0005839 proteasome core complex", "go_biological_process": "GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q3T0T1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3T0X5-1", "uniprot_id": "PSA1_BOVIN", "mass": 29586.0, "length": 263, "protein_name": "Proteasome subunit alpha type-1", "gene_name": "PSMA1", "organism": "Bovine", "refseq_name": "proteasome subunit alpha type-1", "refseq_ac": "NP_001030387", "gene_names_uniprotkb": "PSMA1", "gene_names_refseq": "PSMA1", "protein_names_uniprotkb": "Proteasome subunit alpha type-1", "protein_names_refseq": "proteasome (prosome, macropain) subunit, alpha type, 1; proteasome subunit alpha 1; proteasome subunit alpha type-1", "tax_id": 9913, "disease": "", "pathway": " (bta:515503); (R-BTA-1169091); (R-BTA-1234176); (R-BTA-1236974); (R-BTA-1236978); (R-BTA-174084); (R-BTA-174154); (R-BTA-174178); (R-BTA-174184); (R-BTA-187577); (R-BTA-195253); (R-BTA-202424); (R-BTA-2467813); (R-BTA-2871837); (R-BTA-349425); (R-BTA-350562); (R-BTA-382556); (R-BTA-450408); (R-BTA-4608870); (R-BTA-4641257); (R-BTA-4641258); (R-BTA-5358346); (R-BTA-5607761); (R-BTA-5607764); (R-BTA-5610780); (R-BTA-5610785); (R-BTA-5632684); (R-BTA-5668541); (R-BTA-5676590); (R-BTA-5687128); (R-BTA-5689603); (R-BTA-5689880); (R-BTA-68867); (R-BTA-68949); (R-BTA-69017); (R-BTA-69481); (R-BTA-69601); (R-BTA-75815); (R-BTA-8852276); (R-BTA-8854050); (R-BTA-8939236); (R-BTA-8939902); (R-BTA-8941858); (R-BTA-8948751); (R-BTA-8951664); (R-BTA-9020702); (R-BTA-9755511); (R-BTA-9762114); (R-BTA-9766229); (R-BTA-983168); (R-BTA-9907900); (R-BTA-9912633); (R-BTA-9929356); (R-BTA-9929491); (R-BTA-9931269); (R-BTA-9932298); (R-BTA-9954709)", "pathway_count": 57, "publication_count": 1, "publication_id_list": "12015144", "class_list": "", "function": "Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex)., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0019773 proteasome core complex, alpha-subunit complex;GO:0005839 proteasome core complex", "go_biological_process": "GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0002376 immune system process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q3T0X5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3T0Y8-1", "uniprot_id": "VAMP8_BOVIN", "mass": 11357.0, "length": 100, "protein_name": "Vesicle-associated membrane protein 8", "gene_name": "VAMP8", "organism": "Bovine", "refseq_name": "vesicle-associated membrane protein 8", "refseq_ac": "NP_001029462", "gene_names_uniprotkb": "VAMP8", "gene_names_refseq": "EDB; VAMP8", "protein_names_uniprotkb": "Vesicle-associated membrane protein 8; EDB; Endobrevin; VAMP-8", "protein_names_refseq": "VAMP-8; endobrevin; vesicle-associated membrane protein 8", "tax_id": 9913, "disease": "", "pathway": " (bta:507309); (R-BTA-1236974); (R-BTA-199992); (R-BTA-432720); (R-BTA-432722); (R-BTA-6798695); (R-BTA-8856825); (R-BTA-8856828)", "pathway_count": 8, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "SNAREs (soluble N-ethylmaleimide-sensitive factor-attachment protein receptors) are essential proteins for intracellular membrane fusion. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four-helix bundle whose assembly releases energy that drives membrane fusion. The core SNARE complex typically consists of four alpha-helical domains, three from target membrane SNAREs (t-SNAREs) and one from a vesicle SNARE (v-SNARE). VAMP8 is a v-SNARE that forms a SNARE complex with the t-SNARE STX11 and SNAP23. This SNARE complex plays a critical role in the regulated exocytosis of cytotoxic granules by natural killer (NK) cells and cytotoxic T-lymphocytes. VAMP8 plays a role in autophagy where it controls organelle-organelle membrane fusion through a VAMP8, SNAP29 and STX17 SNARE complex that mediates the fusion of autophagosome and lysososome membranes (By similarity). VAMP8 is required for dense-granule secretion in platelets (By similarity). Also plays a role in regulated enzyme secretion in pancreatic acinar cells (By similarity). Involved in the abscission of the midbody during cell division, which leads to completely separate daughter cells (By similarity). Involved in the homotypic fusion of early and late endosomes (By similarity). Also participates in the activation of type I interferon antiviral response through a TRIM6-dependent mechanism (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0019869 chloride channel inhibitor activity;GO:0019905 syntaxin binding;GO:0005484 SNAP receptor activity", "go_cellular_component": "GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0048471 perinuclear region of cytoplasm;GO:0055037 recycling endosome;GO:0005764 lysosome", "go_biological_process": "GO:0097352 autophagosome maturation;GO:0015031 protein transport;GO:0051607 defense response to virus;GO:0070254 mucus secretion;GO:1903076 regulation of protein localization to plasma membrane", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q3T0Y8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3T106-1", "uniprot_id": "SRSF7_BOVIN", "mass": 26941.0, "length": 235, "protein_name": "Serine/arginine-rich splicing factor 7", "gene_name": "SRSF7", "organism": "Bovine", "refseq_name": "serine/arginine-rich splicing factor 7", "refseq_ac": "NP_001029449", "gene_names_uniprotkb": "SRSF7; SFRS7", "gene_names_refseq": "SFRS7; SRSF7", "protein_names_uniprotkb": "Serine/arginine-rich splicing factor 7; Splicing factor, arginine/serine-rich 7", "protein_names_refseq": "serine/arginine-rich splicing factor 7; splicing factor, arginine/serine-rich 7, 35kDa", "tax_id": 9913, "disease": "", "pathway": " (bta:507066); (R-BTA-159236); (R-BTA-72163); (R-BTA-72165); (R-BTA-72203); (R-BTA-9770562)", "pathway_count": 6, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Required for pre-mRNA splicing. Represses the splicing of MAPT/Tau exon 10. May function as export adapter involved in mRNA nuclear export such as of histone H2A. Binds mRNA which is thought to be transferred to the NXF1-NXT1 heterodimer for export (TAP/NXF1 pathway); enhances NXF1-NXT1 RNA-binding activity. RNA-binding is semi-sequence specific (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 11, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003729 mRNA binding;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0016607 nuclear speck", "go_biological_process": "GO:0006397 mRNA processing;GO:0008380 RNA splicing;GO:0048025 negative regulation of mRNA splicing, via spliceosome;GO:0051028 mRNA transport;GO:0000381 regulation of alternative mRNA splicing, via spliceosome", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q3T106-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3T112-1", "uniprot_id": "PSB8_BOVIN", "mass": 30268.0, "length": 276, "protein_name": "Proteasome subunit beta type-8", "gene_name": "PSMB8", "organism": "Bovine", "refseq_name": "proteasome subunit beta type-8", "refseq_ac": "NP_001035570", "gene_names_uniprotkb": "PSMB8", "gene_names_refseq": "LMP7; PSMB8", "protein_names_uniprotkb": "Proteasome subunit beta type-8; 3.4.25.1; Proteasome subunit beta-5i", "protein_names_refseq": "large multifunctional protease 7; macropain; proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7); proteasome subunit LMP7; proteasome subunit beta 8; proteasome subunit beta type-8; proteasome subunit beta-5i; proteasome subunit, beta type 8", "tax_id": 9913, "disease": "", "pathway": " (bta:282013); (R-BTA-1236974); (R-BTA-1236978); (R-BTA-9907900); (R-BTA-9912633)", "pathway_count": 5, "publication_count": 1, "publication_id_list": "16573526", "class_list": "", "function": "The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit is involved in antigen processing to generate class I binding peptides (By similarity). May participate in the generation of spliced peptides resulting from the ligation of two separate proteasomal cleavage products that are not contiguous in the parental protein (By similarity). Required for adipocyte differentiation (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q32S32", "ec_number_list": "3.4.25.1", "go_molecular_function": "GO:0004175 endopeptidase activity;GO:0004298 threonine-type endopeptidase activity", "go_cellular_component": "GO:0019774 proteasome core complex, beta-subunit complex;GO:1990111 spermatoproteasome complex;GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0045444 fat cell differentiation;GO:0002376 immune system process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q3T112-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3T114-1", "uniprot_id": "RIDA_BOVIN", "mass": 14272.0, "length": 137, "protein_name": "2-iminobutanoate/2-iminopropanoate deaminase", "gene_name": "RIDA", "organism": "Bovine", "refseq_name": "2-iminobutanoate/2-iminopropanoate deaminase", "refseq_ac": "NP_001029380", "gene_names_uniprotkb": "RIDA", "gene_names_refseq": "HRSP12; RIDA", "protein_names_uniprotkb": "2-iminobutanoate/2-iminopropanoate deaminase; 3.1.-.-; 3.5.99.10; Translation inhibitor L-PSP ribonuclease", "protein_names_refseq": "2-iminobutanoate/2-iminopropanoate deaminase; heat-responsive protein 12; ribonuclease UK114; translation inhibitor L-PSP ribonuclease", "tax_id": 9913, "disease": "", "pathway": " (bta:504390); (R-BTA-8849175)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Also promotes endoribonucleolytic cleavage of some transcripts by promoting recruitment of the ribonuclease P/MRP complex. Acts by bridging YTHDF2 and the ribonuclease P/MRP complex. RIDA/HRSP12 binds to N6-methyladenosine (m6A)-containing mRNAs containing a 5'-GGUUC-3' motif: cooperative binding of RIDA/HRSP12 and YTHDF2 to such transcripts lead to recruitment of the ribonuclease P/MRP complex and subsequent endoribonucleolytic cleavage., [UniProtKB, UniProtKB]; Catalyzes the hydrolytic deamination of enamine/imine intermediates that form during the course of normal metabolism. May facilitate the release of ammonia from these potentially toxic reactive metabolites, reducing their impact on cellular components. It may act on enamine/imine intermediates formed by several types of pyridoxal-5'-phosphate-dependent dehydratases including L-threonine dehydratase., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.1.-.-;3.5.99.10", "go_molecular_function": "GO:0003729 mRNA binding;GO:0019239 deaminase activity;GO:0016892 RNA endonuclease activity producing 3'-phosphomonoesters, hydrolytic mechanism;GO:0120242 2-iminobutanoate deaminase activity;GO:0120243 2-iminopropanoate deaminase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix;GO:0005777 peroxisome;GO:0005829 cytosol", "go_biological_process": "GO:0006629 lipid metabolic process;GO:0017148 negative regulation of translation;GO:0006402 mRNA catabolic process;GO:0061157 mRNA destabilization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q3T114-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3T131-1", "uniprot_id": "COQ3_BOVIN", "mass": 41490.0, "length": 370, "protein_name": "Ubiquinone biosynthesis O-methyltransferase, mitochondrial", "gene_name": "COQ3", "organism": "Bovine", "refseq_name": "ubiquinone biosynthesis O-methyltransferase, mitochondrial", "refseq_ac": "NP_001069678", "gene_names_uniprotkb": "COQ3", "gene_names_refseq": "COQ3", "protein_names_uniprotkb": "Ubiquinone biosynthesis O-methyltransferase, mitochondrial; 2.1.1.-; 2.1.1.114; 2.1.1.64; 3-demethylubiquinol 3-O-methyltransferase; 3-demethylubiquinone 3-O-methyltransferase; Polyprenyldihydroxybenzoate methyltransferase", "protein_names_refseq": "2-polyprenyl-6-hydroxyphenol methylase; 2-polyprenyl-6-hydroxyphenyl methylase; 3,4-dihydroxy-5-hexaprenylbenzoate methyltransferase; 3-demethylubiquinol 3-O-methyltransferase; 3-demethylubiquinone 3-O-methyltransferase; 3-demethylubiquinone-n 3-methyltransferase; DHHB methyltransferase; DHHB-MTase; DHHB-MT; coenzyme Q3 homolog, methyltransferase; dihydroxyhexaprenylbenzoate methyltransferase; hexaprenyldihydroxybenzoate methyltransferase, mitochondrial; polyprenyldihydroxybenzoate methyltransferase; ubiquinone biosynthesis O-methyltransferase, mitochondrial", "tax_id": 9913, "disease": "", "pathway": " (bta:540298)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "O-methyltransferase required for two non-consecutive steps during ubiquinone biosynthesis. Catalyzes the 2 O-methylation of 3,4-dihydroxy-5-(all-trans-decaprenyl)benzoic acid into 4-hydroxy-3-methoxy-5-(all-trans-decaprenyl)benzoic acid. Also catalyzes the last step of ubiquinone biosynthesis by mediating methylation of 3-demethylubiquinone into ubiquinone. Also able to mediate the methylation of 3-demethylubiquinol-10 into ubiquinol-10., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.1.1.-;2.1.1.114;2.1.1.64", "go_molecular_function": "GO:0046872 metal ion binding;GO:0010420 polyprenyldihydroxybenzoate methyltransferase activity;GO:0061542 3-demethylubiquinol 3-O-methyltransferase activity;GO:0120537 3-demethylubiquinone 3-O-methyltransferase activity", "go_cellular_component": "GO:0031314 extrinsic component of mitochondrial inner membrane;GO:0005739 mitochondrion", "go_biological_process": "GO:0006744 ubiquinone biosynthetic process;GO:0032259 methylation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q3T131-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3T133-1", "uniprot_id": "TMED9_BOVIN", "mass": 27298.0, "length": 235, "protein_name": "Transmembrane emp24 domain-containing protein 9", "gene_name": "TMED9", "organism": "Bovine", "refseq_name": "transmembrane emp24 domain-containing protein 9 precursor", "refseq_ac": "NP_001029984", "gene_names_uniprotkb": "TMED9", "gene_names_refseq": "TMED9", "protein_names_uniprotkb": "Transmembrane emp24 domain-containing protein 9; p24 family protein alpha-2; p24alpha2", "protein_names_refseq": "p24 family protein alpha-2; p24alpha2; transmembrane emp24 domain-containing protein 9 precursor; transmembrane emp24 domain-containing protein 9", "tax_id": 9913, "disease": "", "pathway": " (bta:618580); (R-BTA-6807878); (R-BTA-6811434)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "Appears to be involved in vesicular protein trafficking, mainly in the early secretory pathway. In COPI vesicle-mediated retrograde transport involved in the coatomer recruitment to membranes of the early secretory pathway. Increases coatomer-dependent activity of ARFGAP2. Thought to play a crucial role in the specific retention of p24 complexes in cis-Golgi membranes; specifically contributes to the coupled localization of TMED2 and TMED10 in the cis-Golgi network. May be involved in organization of intracellular membranes, such as of the ER-Golgi intermediate compartment and the Golgi apparatus. Involved in ER localization of PTPN2 (By similarity)., [UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 1, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "Q5E957", "ec_number_list": "", "go_molecular_function": "GO:0019905 syntaxin binding", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0030134 COPII-coated ER to Golgi transport vesicle;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0048205 COPI coating of Golgi vesicle;GO:0006886 intracellular protein transport;GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0010638 positive regulation of organelle organization;GO:0007030 Golgi organization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q3T133-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3T139-1", "uniprot_id": "R146B_BOVIN", "mass": 37616.0, "length": 347, "protein_name": "E3 ubiquitin-protein ligase RNF146-B", "gene_name": "RNF146B", "organism": "Bovine", "refseq_name": "E3 ubiquitin-protein ligase RNF146-B", "refseq_ac": "NP_001070448", "gene_names_uniprotkb": "RNF146B", "gene_names_refseq": "RNF146B; RNF146", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase RNF146-B; 2.3.2.27; RING finger protein 146-B; RING-type E3 ubiquitin transferase RNF146-B", "protein_names_refseq": "E3 ubiquitin-protein ligase RNF146-B; RING finger protein 146-B; RING-type E3 ubiquitin transferase RNF146-B", "tax_id": 9913, "disease": "", "pathway": " (bta:767901); (R-BTA-201681); (R-BTA-4641257); (R-BTA-5689880); (R-BTA-8948751)", "pathway_count": 5, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "E3 ubiquitin-protein ligase that specifically binds poly-ADP-ribosylated proteins and mediates their ubiquitination and subsequent degradation. Acts as an activator of the Wnt signaling pathway by mediating the ubiquitination of poly-ADP-ribosylated AXIN1 and AXIN2, 2 key components of the beta-catenin destruction complex. Acts in cooperation with tankyrase proteins (TNKS and TNKS2), which mediate poly-ADP-ribosylation of target proteins AXIN1, AXIN2, BLZF1, CASC3, TNKS and TNKS2. Recognizes and binds tankyrase-dependent poly-ADP-ribosylated proteins via its WWE domain and mediates their ubiquitination (By similarity)., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.1.3.67;3.1.3.16;3.1.3.48;2.4.2.-;3.4.19.12;3.4.25.1;2.3.2.27", "go_molecular_function": "GO:0072572 poly-ADP-D-ribose binding;GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity;GO:0004842 ubiquitin-protein transferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005886 plasma membrane", "go_biological_process": "GO:0016055 Wnt signaling pathway;GO:0090263 positive regulation of canonical Wnt signaling pathway;GO:0006511 ubiquitin-dependent protein catabolic process;GO:0051865 protein autoubiquitination;GO:0070936 protein K48-linked ubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q3T139-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3ZBJ1-1", "uniprot_id": "NCBP2_BOVIN", "mass": 18001.0, "length": 156, "protein_name": "Nuclear cap-binding protein subunit 2", "gene_name": "NCBP2", "organism": "Bovine", "refseq_name": "nuclear cap-binding protein subunit 2", "refseq_ac": "NP_001029568", "gene_names_uniprotkb": "NCBP2; CBP20", "gene_names_refseq": "NCBP2", "protein_names_uniprotkb": "Nuclear cap-binding protein subunit 2; 20 kDa nuclear cap-binding protein; CBP20; NCBP 20 kDa subunit", "protein_names_refseq": "20 kDa nuclear cap-binding protein; CBP20; NCBP 20 kDa subunit; nuclear cap binding protein subunit 2, 20kDa; nuclear cap-binding protein subunit 2", "tax_id": 9913, "disease": "", "pathway": " (bta:510872); (R-BTA-111367); (R-BTA-112382); (R-BTA-113418); (R-BTA-159227); (R-BTA-159230); (R-BTA-159231); (R-BTA-159236); (R-BTA-674695); (R-BTA-6803529); (R-BTA-6807505); (R-BTA-72086); (R-BTA-72163); (R-BTA-72165); (R-BTA-72203); (R-BTA-73856); (R-BTA-77588); (R-BTA-77595); (R-BTA-975956); (R-BTA-975957); (R-BTA-9770562); (R-BTA-9930044)", "pathway_count": 22, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of the cap-binding complex (CBC), which binds co-transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense-mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus via its interaction with ALYREF/THOC4/ALY, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U snRNA and intronless mRNAs export from the nucleus. The CBC complex is essential for a pioneer round of mRNA translation, before steady state translation when the CBC complex is replaced by cytoplasmic cap-binding protein eIF4E. The pioneer round of mRNA translation mediated by the CBC complex plays a central role in nonsense-mediated mRNA decay (NMD), NMD only taking place in mRNAs bound to the CBC complex, but not on eIF4E-bound mRNAs. The CBC complex enhances NMD in mRNAs containing at least one exon-junction complex (EJC) via its interaction with UPF1, promoting the interaction between UPF1 and UPF2. The CBC complex is also involved in 'failsafe' NMD, which is independent of the EJC complex, while it does not participate in Staufen-mediated mRNA decay (SMD). During cell proliferation, the CBC complex is also involved in microRNAs (miRNAs) biogenesis via its interaction with SRRT/ARS2, thereby being required for miRNA-mediated RNA interference. The CBC complex also acts as a negative regulator of PARN, thereby acting as an inhibitor of mRNA deadenylation. In the CBC complex, NCBP2/CBP20 recognizes and binds capped RNAs (m7GpppG-capped RNA) but requires NCBP1/CBP80 to stabilize the movement of its N-terminal loop and lock the CBC into a high affinity cap-binding state with the cap structure. The conventional cap-binding complex with NCBP2 binds both small nuclear RNA (snRNA) and messenger (mRNA) and is involved in their export from the nucleus (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003729 mRNA binding;GO:0000340 RNA 7-methylguanosine cap binding;GO:0017069 snRNA binding;GO:0000339 RNA cap binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005846 nuclear cap binding complex", "go_biological_process": "GO:0046833 positive regulation of RNA export from nucleus;GO:0008380 RNA splicing;GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0006446 regulation of translational initiation;GO:0031047 regulatory ncRNA-mediated gene silencing", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q3ZBJ1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3ZBM5-1", "uniprot_id": "SNX5_BOVIN", "mass": 46819.0, "length": 404, "protein_name": "Sorting nexin-5", "gene_name": "SNX5", "organism": "Bovine", "refseq_name": "sorting nexin-5", "refseq_ac": "NP_001029636", "gene_names_uniprotkb": "SNX5", "gene_names_refseq": "SNX5", "protein_names_uniprotkb": "Sorting nexin-5", "protein_names_refseq": "sorting nexin-5", "tax_id": 9913, "disease": "", "pathway": " (bta:514423); (R-BTA-432722)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Involved in several stages of intracellular trafficking. Interacts with membranes containing phosphatidylinositol lipids. Acts in part as component of the retromer membrane-deforming SNX-BAR subcomplex. The SNX-BAR retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN) and is involved in endosome-to-plasma membrane transport for cargo protein recycling. The SNX-BAR subcomplex functions to deform the donor membrane into a tubular profile called endosome-to-TGN transport carrier (ETC). Does not have in vitro vesicle-to-membrane remodeling activity. Involved in retrograde transport of lysosomal enzyme receptor IGF2R. May function as link between endosomal transport vesicles and dynactin. Plays a role in the internalization of EGFR after EGF stimulation. Involved in EGFR endosomal sorting and degradation; the function involves PIP5K1C and is retromer-independent. Together with PIP5K1C facilitates HGS interaction with ubiquitinated EGFR, which initiates EGFR sorting to intraluminal vesicles (ILVs) of the multivesicular body for subsequent lysosomal degradation. Involved in E-cadherin sorting and degradation; inhibits PIP5K1C-mediated E-cadherin degradation. Plays a role in macropinocytosis (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0035091 phosphatidylinositol binding;GO:0034452 dynactin binding", "go_cellular_component": "GO:0001891 phagocytic cup;GO:0005768 endosome;GO:0005829 cytosol;GO:0009898 cytoplasmic side of plasma membrane;GO:0001726 ruffle", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0042147 retrograde transport, endosome to Golgi;GO:0006907 pinocytosis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q3ZBM5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3ZBT6-1", "uniprot_id": "TRA2B_BOVIN", "mass": 33666.0, "length": 288, "protein_name": "Transformer-2 protein homolog beta", "gene_name": "TRA2B", "organism": "Bovine", "refseq_name": "transformer-2 protein homolog beta", "refseq_ac": "NP_001029948", "gene_names_uniprotkb": "TRA2B; SFRS10", "gene_names_refseq": "SFRS10; TRA2B", "protein_names_uniprotkb": "Transformer-2 protein homolog beta; Splicing factor, arginine/serine-rich 10; TRA-2 beta; TRA2-beta; Transformer-2 protein homolog B", "protein_names_refseq": "TRA-2 beta; TRA2-beta; splicing factor, arginine/serine-rich 10 (transformer 2 homolog, Drosophila); transformer-2 protein homolog B; transformer-2 protein homolog beta", "tax_id": 9913, "disease": "", "pathway": " (bta:615156); (R-BTA-72163); (R-BTA-72203); (R-BTA-9013418); (R-BTA-9013422); (R-BTA-9770562)", "pathway_count": 6, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Sequence-specific RNA-binding protein which participates in the control of pre-mRNA splicing (By similarity). Can either activate or suppress exon inclusion. Acts additively with RBMX to promote exon 7 inclusion of the survival motor neuron SMN2. Activates the splicing of MAPT/Tau exon 10. Alters pre-mRNA splicing patterns by antagonizing the effects of splicing regulators, like RBMX. Binds to the AG-rich SE2 domain in the SMN exon 7 RNA. Binds to pre-mRNA (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 16, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003729 mRNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005681 spliceosomal complex", "go_biological_process": "GO:0048026 positive regulation of mRNA splicing, via spliceosome;GO:0043484 regulation of RNA splicing;GO:0000398 mRNA splicing, via spliceosome;GO:0000381 regulation of alternative mRNA splicing, via spliceosome", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q3ZBT6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3ZBU7-1", "uniprot_id": "TBB4A_BOVIN", "mass": 49586.0, "length": 444, "protein_name": "Tubulin beta-4A chain", "gene_name": "TUBB4A", "organism": "Bovine", "refseq_name": "tubulin beta-4A chain", "refseq_ac": "NP_001029869", "gene_names_uniprotkb": "TUBB4A; TUBB4", "gene_names_refseq": "TUBB4A; TUBB4", "protein_names_uniprotkb": "Tubulin beta-4A chain; Tubulin beta-4 chain", "protein_names_refseq": "tubulin beta-4 chain; tubulin beta-4A chain; tubulin, beta 4", "tax_id": 9913, "disease": "", "pathway": " (bta:540236); (R-BTA-2132295); (R-BTA-2467813); (R-BTA-2500257); (R-BTA-2565942); (R-BTA-3371497); (R-BTA-380259); (R-BTA-380270); (R-BTA-380284); (R-BTA-380320); (R-BTA-5620912); (R-BTA-5620924); (R-BTA-6807878); (R-BTA-6811436); (R-BTA-8854518); (R-BTA-9646399); (R-BTA-9648025)", "pathway_count": 17, "publication_count": 3, "publication_id_list": "2207090;6504138;7704569", "class_list": "", "function": "Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers (PubMed:2207090, PubMed:6504138, PubMed:7704569). Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin (PubMed:2207090, PubMed:6504138, PubMed:7704569)., [UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003924 GTPase activity;GO:0005200 structural constituent of cytoskeleton;GO:0005525 GTP binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005874 microtubule", "go_biological_process": "GO:0000278 mitotic cell cycle;GO:0000226 microtubule cytoskeleton organization", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q3ZBU7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3ZC01-1", "uniprot_id": "CNOT7_BOVIN", "mass": 32718.0, "length": 285, "protein_name": "CCR4-NOT transcription complex subunit 7", "gene_name": "CNOT7", "organism": "Bovine", "refseq_name": "CCR4-NOT transcription complex subunit 7", "refseq_ac": "NP_001029484", "gene_names_uniprotkb": "CNOT7; CAF1", "gene_names_refseq": "CNOT7", "protein_names_uniprotkb": "CCR4-NOT transcription complex subunit 7; 3.1.13.4; CAF-1; CCR4-associated factor 1", "protein_names_refseq": "CAF-1; CCR4-NOT transcription complex subunit 7; CCR4-associated factor 1", "tax_id": 9913, "disease": "", "pathway": " (bta:508055); (R-BTA-429947); (R-BTA-6804115)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Has 3'-5' poly(A) exoribonuclease activity for synthetic poly(A) RNA substrate. Its function seems to be partially redundant with that of CNOT8. Catalytic component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. During miRNA-mediated repression the complex also seems to act as translational repressor during translational initiation. Additional complex functions may be a consequence of its influence on mRNA expression. Required for miRNA-mediated mRNA deadenylation. Associates with members of the BTG family such as TOB1 and BTG2 and is required for their anti-proliferative activity (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.3.2.27;3.1.13.4;3.6.4.13", "go_molecular_function": "GO:0046872 metal ion binding;GO:0003714 transcription corepressor activity;GO:0000175 3'-5'-RNA exonuclease activity;GO:0004532 RNA exonuclease activity;GO:0004535 poly(A)-specific ribonuclease activity", "go_cellular_component": "GO:0016607 nuclear speck;GO:0000932 P-body;GO:0030014 CCR4-NOT complex;GO:0030015 CCR4-NOT core complex;GO:0005634 nucleus", "go_biological_process": "GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA;GO:0006351 DNA-templated transcription;GO:0006417 regulation of translation;GO:0008284 positive regulation of cell population proliferation;GO:0008285 negative regulation of cell population proliferation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q3ZC01-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3ZC12-1", "uniprot_id": "EIF3G_BOVIN", "mass": 35655.0, "length": 320, "protein_name": "Eukaryotic translation initiation factor 3 subunit G", "gene_name": "EIF3G", "organism": "Bovine", "refseq_name": "eukaryotic translation initiation factor 3 subunit G", "refseq_ac": "NP_001073091", "gene_names_uniprotkb": "EIF3G; EIF3S4", "gene_names_refseq": "EIF3G; EIF3S4", "protein_names_uniprotkb": "Eukaryotic translation initiation factor 3 subunit G; Eukaryotic translation initiation factor 3 RNA-binding subunit; Eukaryotic translation initiation factor 3 subunit 4; eIF-3 RNA-binding subunit; eIF-3-delta; eIF3 p42; eIF3 p44; eIF3g", "protein_names_refseq": "eukaryotic translation initiation factor 3 subunit G; eukaryotic translation initiation factor 3, subunit 4 delta", "tax_id": 9913, "disease": "", "pathway": " (bta:615695)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression. This subunit can bind 18S rRNA., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 8, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding;GO:0003743 translation initiation factor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0048471 perinuclear region of cytoplasm;GO:0016282 eukaryotic 43S preinitiation complex;GO:0033290 eukaryotic 48S preinitiation complex;GO:0005852 eukaryotic translation initiation factor 3 complex", "go_biological_process": "GO:0006413 translational initiation;GO:0001732 formation of cytoplasmic translation initiation complex", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q3ZC12-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3ZC23-1", "uniprot_id": "RNK_BOVIN", "mass": 11022.0, "length": 98, "protein_name": "Ribonuclease kappa", "gene_name": "RNASEK", "organism": "Bovine", "refseq_name": "ribonuclease kappa", "refseq_ac": "NP_001029601", "gene_names_uniprotkb": "RNASEK", "gene_names_refseq": "RNASEK", "protein_names_uniprotkb": "Ribonuclease kappa; 3.1.-.-; RNase K; RNase kappa; V-ATPase subunit f; V-type proton ATPase subunit f", "protein_names_refseq": "RNase K; RNase kappa; V-ATPase subunit f; V-type proton ATPase subunit f; ribonuclease kappa; ribonuclease, RNase K", "tax_id": 9913, "disease": "", "pathway": " (bta:512886)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32764564", "class_list": "", "function": "Endoribonuclease which preferentially cleaves ApU and ApG phosphodiester bonds. Hydrolyzes UpU bonds at a lower rate (By similarity). Regulates the activity of vacuolar (H+)-ATPase (V-ATPase) which is responsible for acidifying and maintaining the pH of intracellular compartments (By similarity). Required at an early stage of receptor-mediated endocytosis (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0016787 hydrolase activity;GO:0004521 RNA endonuclease activity", "go_cellular_component": "GO:0012505 endomembrane system;GO:0030665 clathrin-coated vesicle membrane;GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain", "go_biological_process": "GO:0006898 receptor-mediated endocytosis;GO:0048388 endosomal lumen acidification;GO:0045851 pH reduction;GO:0019065 receptor-mediated endocytosis of virus by host cell;GO:1902600 proton transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q3ZC23-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3ZC66-1", "uniprot_id": "CRIPT_BOVIN", "mass": 11216.0, "length": 101, "protein_name": "Cysteine-rich PDZ-binding protein", "gene_name": "CRIPT", "organism": "Bovine", "refseq_name": "cysteine-rich PDZ-binding protein", "refseq_ac": "NP_001029975", "gene_names_uniprotkb": "CRIPT", "gene_names_refseq": "CRIPT", "protein_names_uniprotkb": "Cysteine-rich PDZ-binding protein; Cysteine-rich interactor of PDZ three; Cysteine-rich interactor of PDZ3", "protein_names_refseq": "cysteine-rich PDZ-binding protein; cysteine-rich interactor of PDZ three; cysteine-rich interactor of PDZ3; postsynaptic protein CRIPT", "tax_id": 9913, "disease": "", "pathway": " (bta:617723)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "17474715", "class_list": "", "function": "As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (By similarity). Involved in the cytoskeletal anchoring of DLG4 in excitatory synapses., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008017 microtubule binding;GO:0044877 protein-containing complex binding;GO:0030165 PDZ domain binding;GO:0097110 scaffold protein binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0014069 postsynaptic density;GO:0030425 dendrite;GO:0043025 neuronal cell body;GO:0043197 dendritic spine", "go_biological_process": "GO:0006397 mRNA processing;GO:0008380 RNA splicing;GO:0031122 cytoplasmic microtubule organization;GO:1902897 regulation of postsynaptic density protein 95 clustering;GO:0035372 protein localization to microtubule", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q3ZC66-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3ZC89-1", "uniprot_id": "MAP2_BOVIN", "mass": 52812.0, "length": 477, "protein_name": "Methionine aminopeptidase 2", "gene_name": "METAP2", "organism": "Bovine", "refseq_name": "methionine aminopeptidase 2", "refseq_ac": "NP_001035583", "gene_names_uniprotkb": "METAP2", "gene_names_refseq": "METAP2; p67eIF2; p67", "protein_names_uniprotkb": "Methionine aminopeptidase 2; 3.4.11.18; Initiation factor 2-associated 67 kDa glycoprotein; MAP 2; MetAP 2; Peptidase M; p67eIF2; p67", "protein_names_refseq": "MAP 2; initiation factor 2-associated 67 kDa glycoprotein; metAP 2; methionine aminopeptidase 2; peptidase M 2", "tax_id": 9913, "disease": "", "pathway": " (bta:404150)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val)., [UniProtKB, HAMAP]; Protects eukaryotic initiation factor EIF2S1 from translation-inhibiting phosphorylation by inhibitory kinases such as EIF2AK2/PKR and EIF2AK1/HCR. Plays a critical role in the regulation of protein synthesis., [UniProtKB, HAMAP]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0046872 metal ion binding;GO:0004177 aminopeptidase activity;GO:0008235 metalloexopeptidase activity;GO:0070006 metalloaminopeptidase activity;GO:0004239 initiator methionyl aminopeptidase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0006508 proteolysis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q3ZC89-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3ZC91-1", "uniprot_id": "ASM3A_BOVIN", "mass": 51221.0, "length": 450, "protein_name": "Cyclic GMP-AMP phosphodiesterase SMPDL3A", "gene_name": "SMPDL3A", "organism": "Bovine", "refseq_name": "cyclic GMP-AMP phosphodiesterase SMPDL3A precursor", "refseq_ac": "NP_001030191", "gene_names_uniprotkb": "SMPDL3A", "gene_names_refseq": "SMPDL3A", "protein_names_uniprotkb": "Cyclic GMP-AMP phosphodiesterase SMPDL3A; 2',3'-cGAMP phosphodiesterase SMPDL3A; 3.1.4.-; 3.6.1.15; ASM-like phosphodiesterase 3a; Acid sphingomyelinase-like phosphodiesterase 3a", "protein_names_refseq": "2',3'-cGAMP phosphodiesterase SMPDL3A; ASM-like phosphodiesterase 3a; acid sphingomyelinase-like phosphodiesterase 3a; cyclic GMP-AMP phosphodiesterase SMPDL3A precursor; cyclic GMP-AMP phosphodiesterase SMPDL3A", "tax_id": 9913, "disease": "", "pathway": " (bta:505300)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Cyclic-nucleotide phosphodiesterase that acts as a negative regulator of innate immunity by mediating degradation of 2',3'-cGAMP, thereby inhibiting the cGAS-STING signaling. Specifically linearizes 2',3'-cGAMP into 2'5'-bond pGpA and further hydrolyzes pGpA to produce GpA. Also has in vitro nucleotide phosphodiesterase activity with nucleoside triphosphates, such as ATP. Has in vitro activity with p-nitrophenyl-TMP. Has lower activity with nucleoside diphosphates, and no activity with nucleoside monophosphates. Has in vitro activity with CDP-choline, giving rise to CMP and phosphocholine. Has in vitro activity with CDP-ethanolamine. Does not have sphingomyelin phosphodiesterase activity., [UniProtKB, UniProtKB]", "predicted_glycosites": 7, "predicted_n_glycosites": 6, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 7, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.6.4.12;5.6.2.4;3.6.4.13;2.3.2.27;7.2.2.-;2.7.7.7;2.7.7.49;3.6.1.5;3.6.4.6;3.6.4.10;5.6.2.3;3.6.5.-;5.6.2.-;2.7.4.3;3.6.4.-;2.7.11.1;3.1.-.-;4.2.99.18;5.6.1.6;3.6.1.15;7.6.2.1;3.1.3.1;3.9.1.1;5.6.2.5;3.4.24.-;3.6.-.-;3.6.1.-;5.6.1.7;3.1.4.-;3.4.21.53", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0016887 ATP hydrolysis activity;GO:0008081 phosphoric diester hydrolase activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0005615 extracellular space", "go_biological_process": "GO:0009143 nucleoside triphosphate catabolic process;GO:0160049 negative regulation of cGAS/STING signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q3ZC91-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3ZCA2-1", "uniprot_id": "CPSF5_BOVIN", "mass": 26227.0, "length": 227, "protein_name": "Cleavage and polyadenylation specificity factor subunit 5", "gene_name": "NUDT21", "organism": "Bovine", "refseq_name": "cleavage and polyadenylation specificity factor subunit 5", "refseq_ac": "NP_001030408", "gene_names_uniprotkb": "NUDT21; CPSF5", "gene_names_refseq": "NUDT21", "protein_names_uniprotkb": "Cleavage and polyadenylation specificity factor subunit 5; Nucleoside diphosphate-linked moiety X motif 21; Nudix motif 21", "protein_names_refseq": "cleavage and polyadenylation specificity factor subunit 5; nucleoside diphosphate-linked moiety X motif 21; nudix (nucleoside diphosphate linked moiety X)-type motif 21; nudix motif 21", "tax_id": 9913, "disease": "", "pathway": " (bta:518859); (R-BTA-73856); (R-BTA-77595); (R-BTA-9770562)", "pathway_count": 4, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The CFIm complex acts as a key regulator of cleavage and polyadenylation site choice during APA through its binding to 5'-UGUA-3' elements localized in the 3'-untranslated region (UTR) for a huge number of pre-mRNAs. NUDT21/CPSF5 activates indirectly the mRNA 3'-processing machinery by recruiting CPSF6 and/or CPSF7. Binds to 5'-UGUA-3' elements localized upstream of pA signals that act as enhancers of pre-mRNA 3'-end processing. The homodimer mediates simultaneous sequence-specific recognition of two 5'-UGUA-3' elements within the pre-mRNA. Plays a role in somatic cell fate transitions and pluripotency by regulating widespread changes in gene expression through an APA-dependent function. Binds to chromatin. Binds to, but does not hydrolyze mono- and di-adenosine nucleotides., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003682 chromatin binding;GO:0003729 mRNA binding;GO:0042802 identical protein binding;GO:0035925 mRNA 3'-UTR AU-rich region binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005849 mRNA cleavage factor complex;GO:0042382 paraspeckles", "go_biological_process": "GO:0006397 mRNA processing;GO:0051290 protein heterotetramerization;GO:0031124 mRNA 3'-end processing;GO:0110104 mRNA alternative polyadenylation;GO:0180010 co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q3ZCA2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3ZCF6-1", "uniprot_id": "APC11_BOVIN", "mass": 9846.0, "length": 84, "protein_name": "Anaphase-promoting complex subunit 11", "gene_name": "ANAPC11", "organism": "Bovine", "refseq_name": "anaphase-promoting complex subunit 11", "refseq_ac": "NP_001107196", "gene_names_uniprotkb": "ANAPC11", "gene_names_refseq": "ANAPC11", "protein_names_uniprotkb": "Anaphase-promoting complex subunit 11; APC11; Cyclosome subunit 11", "protein_names_refseq": "APC11 anaphase promoting complex subunit 11 homolog; anaphase-promoting complex subunit 11; cyclosome subunit 11", "tax_id": 9913, "disease": "", "pathway": " (bta:616275); (R-BTA-141430); (R-BTA-174048); (R-BTA-174084); (R-BTA-174154); (R-BTA-174178); (R-BTA-174184); (R-BTA-176407); (R-BTA-176408); (R-BTA-176409); (R-BTA-176412); (R-BTA-179409); (R-BTA-2467813); (R-BTA-2559582); (R-BTA-68867); (R-BTA-69017); (R-BTA-983168)", "pathway_count": 17, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through the cell cycle (By similarity). Together with ANAPC2, forms the catalytic component of the E3 ubiquitin ligase complex (By similarity). APC/C acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains (By similarity). APC/C catalyzes assembly of branched 'Lys-11'-/'Lys-48'-linked branched ubiquitin chains on target proteins (By similarity). APC/C is activated by CDC20 in the metaphase/anaphase transition of cell cycle, targeting the degradation of cyclin B and securin (By similarity). APC/C is regulated by the mitotic checkpoint complex (MCC), which inhibits APC/C and delays chromosome segregation (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity;GO:0097602 cullin family protein binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005680 anaphase-promoting complex", "go_biological_process": "GO:0051301 cell division;GO:0016567 protein ubiquitination;GO:0031145 anaphase-promoting complex-dependent catabolic process;GO:0070979 protein K11-linked ubiquitination;GO:0045842 positive regulation of mitotic metaphase/anaphase transition", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q3ZCF6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3ZCJ8-1", "uniprot_id": "CATC_BOVIN", "mass": 51949.0, "length": 463, "protein_name": "Dipeptidyl peptidase 1", "gene_name": "CTSC", "organism": "Bovine", "refseq_name": "dipeptidyl peptidase 1 precursor", "refseq_ac": "NP_001028789", "gene_names_uniprotkb": "CTSC", "gene_names_refseq": "CTSC", "protein_names_uniprotkb": "Dipeptidyl peptidase 1; 3.4.14.1; Cathepsin C; Cathepsin J; DPP-I; DPPI; Dipeptidyl peptidase I exclusion domain chain; Dipeptidyl peptidase I heavy chain; Dipeptidyl peptidase I light chain; Dipeptidyl peptidase I; Dipeptidyl transferase", "protein_names_refseq": "DPP-I; DPPI; cathepsin J; dipeptidyl peptidase 1 precursor; dipeptidyl peptidase 1; dipeptidyl peptidase I; dipeptidyl transferase", "tax_id": 9913, "disease": "", "pathway": " (bta:352958)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Thiol protease. Has dipeptidylpeptidase activity. Active against a broad range of dipeptide substrates composed of both polar and hydrophobic amino acids. Proline cannot occupy the P1 position and arginine cannot occupy the P2 position of the substrate. Can act as both an exopeptidase and endopeptidase. Activates serine proteases such as elastase, cathepsin G and granzymes A and B., [UniProtKB, UniProtKB]", "predicted_glycosites": 4, "predicted_n_glycosites": 4, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008239 dipeptidyl-peptidase activity;GO:0004197 cysteine-type endopeptidase activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005764 lysosome", "go_biological_process": "GO:0051603 proteolysis involved in protein catabolic process;GO:0031638 zymogen activation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q3ZCJ8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3ZCK3-1", "uniprot_id": "BPNT1_BOVIN", "mass": 33328.0, "length": 308, "protein_name": "3'(2'),5'-bisphosphate nucleotidase 1", "gene_name": "BPNT1", "organism": "Bovine", "refseq_name": "3'(2'),5'-bisphosphate nucleotidase 1", "refseq_ac": "NP_001029711", "gene_names_uniprotkb": "BPNT1", "gene_names_refseq": "BPNT1", "protein_names_uniprotkb": "3'(2'),5'-bisphosphate nucleotidase 1; 3'-phosphoadenosine 5'-phosphate phosphatase; 3.1.3.57; 3.1.3.7; BPntase 1; Bisphosphate 3'-nucleotidase 1; Inositol-polyphosphate 1-phosphatase; PAP phosphatase", "protein_names_refseq": "3'(2'),5'-bisphosphate nucleotidase 1; 3'-phosphoadenosine 5'-phosphate phosphatase; BPntase 1; PAP phosphatase; bisphosphate 3'-nucleotidase 1; inositol-polyphosphate 1-phosphatase", "tax_id": 9913, "disease": "", "pathway": " (bta:521254); (R-BTA-156584)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "Phosphatase that converts 3'(2')-phosphoadenosine 5'-phosphate (PAP) to AMP and adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS). Is also able to hydrolyze inositol 1,4-bisphosphate (Ins(1,4)P2) and inositol 1,3,4-trisphosphate (Ins(1,3,4)P3), but is not active on AMP, 3'-AMP, fructose-1,6-bisphosphate, Ins(1)P, Ins(2)P and Ins(1,4,5)P3. Probably prevents the toxic accumulation of PAP, a compound which inhibits a variety of proteins, including PAPS-utilizing enzymes such as sulfotransferases, and RNA processing enzymes. Could also play a role in inositol recycling and phosphoinositide metabolism., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A7E3X5", "ec_number_list": "3.1.3.57;3.1.3.7", "go_molecular_function": "GO:0004441 inositol-1,4-bisphosphate 1-phosphatase activity;GO:0046872 metal ion binding;GO:0008441 3'(2'),5'-bisphosphate nucleotidase activity", "go_cellular_component": "", "go_biological_process": "GO:0046854 phosphatidylinositol phosphate biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q3ZCK3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3ZCL3-1", "uniprot_id": "NMI_BOVIN", "mass": 35395.0, "length": 309, "protein_name": "N-myc-interactor", "gene_name": "NMI", "organism": "Bovine", "refseq_name": "N-myc-interactor", "refseq_ac": "NP_001030270", "gene_names_uniprotkb": "NMI", "gene_names_refseq": "NMI", "protein_names_uniprotkb": "N-myc-interactor; N-myc and STAT interactor; Nmi", "protein_names_refseq": "N-myc-interactor", "tax_id": 9913, "disease": "", "pathway": " (bta:511280)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "30573663", "class_list": "", "function": "Acts as a signaling pathway regulator involved in innate immune system response. In response to interleukin 2/IL2 and interferon IFN-gamma/IFNG, interacts with signal transducer and activator of transcription/STAT which activate the transcription of downstream genes involved in a multitude of signals for development and homeostasis. Enhances the recruitment of CBP/p300 coactivators to STAT1 and STAT5, resulting in increased STAT1- and STAT5-dependent transcription. In response to interferon IFN-alpha, associates in a complex with signaling pathway regulator IFI35 to regulate immune response; the complex formation prevents proteasome-mediated degradation of IFI35. In complex with IFI35, inhibits virus-triggered type I IFN-beta production when ubiquitinated by ubiquitin-protein ligase TRIM21. In complex with IFI35, negatively regulates nuclear factor NF-kappa-B signaling by inhibiting the nuclear translocation, activation and transcription of NF-kappa-B subunit p65/RELA, resulting in the inhibition of endothelial cell proliferation, migration and re-endothelialization of injured arteries (By similarity). Negatively regulates virus-triggered type I interferon/IFN production by inducing proteosome-dependent degradation of IRF7, a transcriptional regulator of type I IFN, thereby interfering with cellular antiviral responses (By similarity). Beside its role as an intracellular signaling pathway regulator, also functions extracellularly as damage-associated molecular patterns (DAMPs) to promote inflammation, when actively released by macrophage to the extracellular space during cell injury or pathogen invasion. Macrophage-secreted NMI activates NF-kappa-B signaling in adjacent macrophages through Toll-like receptor 4/TLR4 binding and activation, thereby inducing NF-kappa-B translocation from the cytoplasm into the nucleus which promotes the release of pro-inflammatory cytokines (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005615 extracellular space;GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0016020 membrane", "go_biological_process": "GO:0008285 negative regulation of cell population proliferation;GO:0045087 innate immune response;GO:1901224 positive regulation of non-canonical NF-kappaB signal transduction;GO:0050729 positive regulation of inflammatory response;GO:1901223 negative regulation of non-canonical NF-kappaB signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q3ZCL3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q4JF29-1", "uniprot_id": "TCAM1_BOVIN", "mass": 82359.0, "length": 759, "protein_name": "TIR domain-containing adapter molecule 1", "gene_name": "TICAM1", "organism": "Bovine", "refseq_name": "TIR domain-containing adapter molecule 1", "refseq_ac": "NP_001025472", "gene_names_uniprotkb": "TICAM1; TRIF", "gene_names_refseq": "TICAM1; TRIF", "protein_names_uniprotkb": "TIR domain-containing adapter molecule 1; TICAM-1; TIR domain-containing adapter protein inducing IFN-beta; Toll-interleukin-1 receptor domain-containing adapter protein inducing interferon beta", "protein_names_refseq": "TICAM-1; TIR domain containing adaptor inducing interferon-beta; TIR domain-containing adapter molecule 1; TIR domain-containing adapter protein inducing IFN-beta; toll like receptor adaptor molecule 1; toll-interleukin-1 receptor domain-containing adapter protein inducing interferon beta", "tax_id": 9913, "disease": "", "pathway": " (bta:510427)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "24075204", "class_list": "", "function": "Inhibition of the Toll/interleukin-1 receptor (TIR) domain-containing adapter-inducing interferon-beta signaling reduced permeability changes and apoptosis in endothelial cells exposed to lipopolysaccharide., [RefSeq, PubMed]; Involved in innate immunity against invading pathogens. Adapter used by TLR3, TLR4 (through TICAM2) and TLR5 to mediate NF-kappa-B and interferon-regulatory factor (IRF) activation, and to induce apoptosis. Ligand binding to these receptors results in TRIF recruitment through its TIR domain. Distinct protein-interaction motifs allow recruitment of the effector proteins TBK1, TRAF6 and RIPK1, which in turn, lead to the activation of transcription factors IRF3 and IRF7, NF-kappa-B and FADD respectively. Phosphorylation by TBK1 on the pLxIS motif leads to recruitment and subsequent activation of the transcription factor IRF3 to induce expression of type I interferon and exert a potent immunity against invading pathogens (By similarity). Component of a multi-helicase-TICAM1 complex that acts as a cytoplasmic sensor of viral double-stranded RNA (dsRNA) and plays a role in the activation of a cascade of antiviral responses including the induction of pro-inflammatory cytokines (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "A7E2Y9", "ec_number_list": "", "go_molecular_function": "GO:0035591 signaling adaptor activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005768 endosome;GO:0005829 cytosol;GO:0005776 autophagosome", "go_biological_process": "GO:0006954 inflammatory response;GO:0007166 cell surface receptor signaling pathway;GO:0045087 innate immune response;GO:0051607 defense response to virus;GO:0006915 apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q4JF29-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q4JIJ3-1", "uniprot_id": "METH_BOVIN", "mass": 140478.0, "length": 1265, "protein_name": "Methionine synthase", "gene_name": "MTR", "organism": "Bovine", "refseq_name": "methionine synthase", "refseq_ac": "NP_001025469", "gene_names_uniprotkb": "MTR", "gene_names_refseq": "MTR", "protein_names_uniprotkb": "Methionine synthase; 2.1.1.13; 5-methyltetrahydrofolate--homocysteine methyltransferase; Cobalamin-dependent methionine synthase; MS; Vitamin-B12 dependent methionine synthase", "protein_names_refseq": "MS; cobalamin-dependent methionine synthase; methionine synthase; vitamin-B12 dependent methionine synthase", "tax_id": 9913, "disease": "", "pathway": " (bta:280869)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "27881594", "class_list": "", "function": "Catalyzes the transfer of a methyl group from methylcob(III)alamin (MeCbl) to homocysteine, yielding enzyme-bound cob(I)alamin and methionine in the cytosol. MeCbl is an active form of cobalamin (vitamin B12) used as a cofactor for methionine biosynthesis. Cob(I)alamin form is regenerated to MeCbl by a transfer of a methyl group from 5-methyltetrahydrofolate. The processing of cobalamin in the cytosol occurs in a multiprotein complex composed of at least MMACHC, MMADHC, MTRR (methionine synthase reductase) and MTR which may contribute to shuttle safely and efficiently cobalamin towards MTR in order to produce methionine., [UniProtKB, UniProtKB]; These findings indicate that greater synthesis of phosphatidylcholine and antioxidants contribute to the better performance and immuno-metabolic status in methionine-supplemented cows., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.1.1.13", "go_molecular_function": "GO:0008705 methionine synthase activity;GO:0008270 zinc ion binding;GO:0031419 cobalamin binding", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0032259 methylation;GO:0046653 tetrahydrofolate metabolic process;GO:0009086 methionine biosynthetic process;GO:0050667 homocysteine metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q4JIJ3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q52PG9-1", "uniprot_id": "KCND1_BOVIN", "mass": 71378.0, "length": 648, "protein_name": "A-type voltage-gated potassium channel KCND1", "gene_name": "KCND1", "organism": "Bovine", "refseq_name": "A-type voltage-gated potassium channel KCND1", "refseq_ac": "NP_001019724", "gene_names_uniprotkb": "KCND1", "gene_names_refseq": "KCND1", "protein_names_uniprotkb": "A-type voltage-gated potassium channel KCND1; Potassium voltage-gated channel subfamily D member 1; Voltage-gated potassium channel subunit Kv4.1", "protein_names_refseq": "A-type voltage-gated potassium channel KCND1; potassium voltage-gated channel, Shal-related subfamily, member 1; voltage-gated potassium channel subunit Kv4.1; voltage-gated shal-type potassium channel member 1", "tax_id": 9913, "disease": "", "pathway": " (bta:518384); (R-BTA-1296072); (R-BTA-5576894)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "A-type voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes in the brain. Mediates A-type current I(SA) in suprachiasmatic nucleus (SCN) neurons. Exhibits a low-threshold A-type current with a hyperpolarized steady-state inactivation midpoint and the recovery process was steeply voltage-dependent, with recovery being markedly faster at more negative potentials. May regulates repetitive firing rates in the suprachiasmatic nucleus (SCN) neurons and circadian rhythms in neuronal excitability and behavior. Contributes to the regulation of the circadian rhythm of action potential firing in suprachiasmatic nucleus neurons, which regulates the circadian rhythm of locomotor activity. The regulatory subunit KCNIP1 modulates the kinetics of channel inactivation, increases the current amplitudes and accelerates recovery from inactivation, shifts activation in a depolarizing direction (By similarity). The regulatory subunit DPP10 decreases the voltage sensitivity of the inactivation channel gating (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.8.-.-", "go_molecular_function": "GO:0046872 metal ion binding;GO:0005250 A-type (transient outward) potassium channel activity", "go_cellular_component": "GO:0043025 neuronal cell body;GO:0043197 dendritic spine;GO:0045211 postsynaptic membrane;GO:0008076 voltage-gated potassium channel complex", "go_biological_process": "GO:0051260 protein homooligomerization;GO:0001508 action potential;GO:0071805 potassium ion transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q52PG9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q58CQ9-1", "uniprot_id": "VNN1_BOVIN", "mass": 56947.0, "length": 510, "protein_name": "Pantetheinase", "gene_name": "VNN1", "organism": "Bovine", "refseq_name": "pantetheinase precursor", "refseq_ac": "NP_001019727", "gene_names_uniprotkb": "VNN1", "gene_names_refseq": "VNN1", "protein_names_uniprotkb": "Pantetheinase; 3.5.1.92; Pantetheine hydrolase; Vanin-1; Vascular non-inflammatory molecule 1", "protein_names_refseq": "pantetheinase precursor; pantetheinase; pantetheine hydrolase; vascular non-inflammatory molecule 1", "tax_id": 9913, "disease": "", "pathway": " (bta:526704)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "16305752;19674964", "class_list": "", "function": "Amidohydrolase that hydrolyzes specifically one of the carboamide linkages in D-pantetheine thus recycling pantothenic acid (vitamin B5) and releasing cysteamine., [UniProtKB, UniProtKB]", "predicted_glycosites": 7, "predicted_n_glycosites": 6, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 1, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 9015, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 8, "binding_glycan_count": 0, "secondary_ac_list": "A6QPH4", "ec_number_list": "3.5.1.92", "go_molecular_function": "GO:0017159 pantetheine hydrolase activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0098552 side of membrane", "go_biological_process": "GO:0015939 pantothenate metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q58CQ9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q58CS7-1", "uniprot_id": "CHMP3_BOVIN", "mass": 25017.0, "length": 222, "protein_name": "Charged multivesicular body protein 3", "gene_name": "CHMP3", "organism": "Bovine", "refseq_name": "charged multivesicular body protein 3", "refseq_ac": "NP_001030223", "gene_names_uniprotkb": "CHMP3; VPS24", "gene_names_refseq": "CHMP3; VPS24", "protein_names_uniprotkb": "Charged multivesicular body protein 3; Chromatin-modifying protein 3; Vacuolar protein sorting-associated protein 24", "protein_names_refseq": "charged multivesicular body protein 3; chromatin-modifying protein 3; vacuolar protein sorting 24 homolog; vacuolar protein sorting-associated protein 24", "tax_id": 9913, "disease": "", "pathway": " (bta:507722); (R-BTA-1632852); (R-BTA-5620971); (R-BTA-917729); (R-BTA-9668328)", "pathway_count": 5, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and the budding of enveloped viruses (lentiviruses). ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or membrane fission activities, possibly in conjunction with the AAA ATPase VPS4. Selectively binds to phosphatidylinositol 3,5-bisphosphate PtdIns(3,5)P2 and PtdIns(3,4)P2 in preference to other phosphoinositides tested. Involved in late stages of cytokinesis. Plays a role in endosomal sorting/trafficking of EGF receptor (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q29RQ4", "ec_number_list": "", "go_molecular_function": "GO:0031210 phosphatidylcholine binding;GO:1990381 ubiquitin-specific protease binding;GO:0180020 membrane bending activity", "go_cellular_component": "GO:0000815 ESCRT III complex;GO:0005828 kinetochore microtubule;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0005765 lysosomal membrane", "go_biological_process": "GO:0001778 plasma membrane repair;GO:0010824 regulation of centrosome duplication;GO:0031468 nuclear membrane reassembly;GO:0039702 viral budding via host ESCRT complex;GO:0061763 multivesicular body-lysosome fusion", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q58CS7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q58CS8-1", "uniprot_id": "GNPTG_BOVIN", "mass": 33783.0, "length": 306, "protein_name": "N-acetylglucosamine-1-phosphotransferase subunit gamma", "gene_name": "GNPTG", "organism": "Bovine", "refseq_name": "N-acetylglucosamine-1-phosphotransferase subunit gamma", "refseq_ac": "NP_001017428", "gene_names_uniprotkb": "GNPTG", "gene_names_refseq": "GNPTG", "protein_names_uniprotkb": "N-acetylglucosamine-1-phosphotransferase subunit gamma; GlcNAc-1-phosphotransferase subunit gamma; UDP-N-acetylglucosamine-1-phosphotransferase subunit gamma", "protein_names_refseq": "N-acetylglucosamine-1-phosphate transferase gamma subunit; N-acetylglucosamine-1-phosphotransferase subunit gamma; N-acetylglucosamine-1-phosphotransferase, gamma subunit; UDP-N-acetylglucosamine-1-phosphotransferase subunit gamma; glcNAc-1-phosphotransferase subunit gamma", "tax_id": 9913, "disease": "", "pathway": " (bta:508713)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "16305752;19955174;8940155", "class_list": "", "function": "Analysis of functional differences in alpha, beta, and gamma subunits of UDP-GlcNAc:lysosomal enzyme N-acetylglucosamine-1-phosphotransferase, [RefSeq, PubMed]; Non-catalytic subunit of the N-acetylglucosamine-1-phosphotransferase complex, an enzyme that catalyzes the formation of mannose 6-phosphate (M6P) markers on high mannose type oligosaccharides in the Golgi apparatus. Binds and presents the high mannose glycans of the acceptor to the catalytic alpha and beta subunits (GNPTAB). Enhances the rate of N-acetylglucosamine-1-phosphate transfer to the oligosaccharides of acid hydrolase acceptors (By similarity)., [UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "A5PJW7", "ec_number_list": "", "go_molecular_function": "GO:0042803 protein homodimerization activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0005794 Golgi apparatus", "go_biological_process": "GO:0046835 carbohydrate phosphorylation", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q58CS8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q58CT0-1", "uniprot_id": "DYH12_BOVIN", "mass": 39862.0, "length": 356, "protein_name": "Dynein axonemal heavy chain 12", "gene_name": "DNAH12", "organism": "Bovine", "refseq_name": "dynein axonemal heavy chain 12", "refseq_ac": "NP_001030242", "gene_names_uniprotkb": "DNAH12; ASB14", "gene_names_refseq": "ASB14; DNAH12", "protein_names_uniprotkb": "Dynein axonemal heavy chain 12; ASB-14; Ankyrin repeat and SOCS box protein 14; Axonemal beta dynein heavy chain 12; Ciliary dynein heavy chain 12", "protein_names_refseq": "ASB-14; ankyrin repeat and SOCS box protein 14; ankyrin repeat and SOCS box-containing protein 14; axonemal beta dynein heavy chain 12; ciliary dynein heavy chain 12; dynein axonemal heavy chain 12; dynein heavy chain 12, axonemal", "tax_id": 9913, "disease": "", "pathway": " (bta:509431)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "Involved in spermiogenesis. Plays a role in the proper organization of axoneme in sperm flagella, but not in cilia, by recruiting DNAH1 and DNALI1 to flagellum., [UniProtKB, UniProtKB]; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A6QNK5", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding", "go_cellular_component": "GO:0005874 microtubule;GO:0036126 sperm flagellum;GO:0030286 dynein complex", "go_biological_process": "GO:0035556 intracellular signal transduction;GO:0007286 spermatid development;GO:0016567 protein ubiquitination;GO:0007288 sperm axoneme assembly", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q58CT0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q58CW0-1", "uniprot_id": "NUD11_BOVIN", "mass": 18519.0, "length": 164, "protein_name": "Diphosphoinositol polyphosphate phosphohydrolase 3-beta", "gene_name": "NUDT11", "organism": "Bovine", "refseq_name": "diphosphoinositol polyphosphate phosphohydrolase 3-alpha", "refseq_ac": "NP_001030565", "gene_names_uniprotkb": "NUDT11; DIPP3B", "gene_names_refseq": "NUDT10; NUDT11", "protein_names_uniprotkb": "Diphosphoinositol polyphosphate phosphohydrolase 3-beta; 3.6.1.52; 3.6.1.60; DIPP-3-beta; DIPP3-beta; Diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase 3-beta; Diadenosine hexaphosphate hydrolase (AMP-forming); Nucleoside diphosphate-linked moiety X motif 11; Nudix motif 11", "protein_names_refseq": "DIPP-3-beta; DIPP3-beta; diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase 3-beta; diphosphoinositol polyphosphate phosphohydrolase 3-alpha; diphosphoinositol polyphosphate phosphohydrolase 3-beta; nucleoside diphosphate-linked moiety X motif 11; nudix (nucleoside diphosphate linked moiety X)-type motif 11; nudix motif 11; nudix-type motif 10", "tax_id": 9913, "disease": "", "pathway": " (bta:616931)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "Cleaves a beta-phosphate from the diphosphate groups in PP-InsP5 (diphosphoinositol pentakisphosphate), suggesting that it may play a role in signal transduction. Also able to catalyze the hydrolysis of dinucleoside oligophosphates, with Ap6A and Ap5A being the preferred substrates. The major reaction products are ADP and p4a from Ap6A and ADP and ATP from Ap5A. Also able to hydrolyze 5-phosphoribose 1-diphosphate., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.6.1.-;3.1.4.1;3.6.1.9;3.6.1.52;3.6.1.60", "go_molecular_function": "GO:0000298 endopolyphosphatase activity;GO:0008486 diphosphoinositol-polyphosphate diphosphatase activity;GO:0034431 bis(5'-adenosyl)-hexaphosphatase activity;GO:0034432 bis(5'-adenosyl)-pentaphosphatase activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0071543 diphosphoinositol polyphosphate metabolic process;GO:1901907 diadenosine pentaphosphate catabolic process;GO:1901909 diadenosine hexaphosphate catabolic process;GO:1901911 adenosine 5'-(hexahydrogen pentaphosphate) catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q58CW0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q58D49-1", "uniprot_id": "MMAB_BOVIN", "mass": 26587.0, "length": 241, "protein_name": "Corrinoid adenosyltransferase MMAB", "gene_name": "MMAB", "organism": "Bovine", "refseq_name": "corrinoid adenosyltransferase MMAB precursor", "refseq_ac": "NP_001073100", "gene_names_uniprotkb": "MMAB", "gene_names_refseq": "ATR; MMAB", "protein_names_uniprotkb": "Corrinoid adenosyltransferase MMAB; 2.5.1.-; ATP:co(I)rrinoid adenosyltransferase MMAB; Methylmalonic aciduria type B homolog", "protein_names_refseq": "ATP:co(I)rrinoid adenosyltransferase MMAB; cob(I)alamin adenosyltransferase; cob(I)yrinic acid a,c-diamide adenosyltransferase, mitochondrial; cob(II)alamin adenosyltransferase; cob(II)yrinic acid a,c-diamide adenosyltransferase; cobinamide/cobalamin adenosyltransferase; corrinoid adenosyltransferase MMAB precursor; corrinoid adenosyltransferase MMAB; corrinoid adenosyltransferase; methylmalonic aciduria (cobalamin deficiency) cblB type; methylmalonic aciduria (cobalamin deficiency) type B; methylmalonic aciduria type B homolog", "tax_id": 9913, "disease": "", "pathway": " (bta:617636)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "12514191;16305752", "class_list": "", "function": "Converts cob(I)alamin to adenosylcobalamin (adenosylcob(III)alamin), a coenzyme for methylmalonyl-CoA mutase, therefore participates in the final step of the vitamin B12 conversion (PubMed:12514191). Generates adenosylcobalamin (AdoCbl) and directly delivers the cofactor to MUT in a transfer that is stimulated by ATP-binding to MMAB and gated by MMAA (By similarity)., [UniProtKB, UniProtKB, PubMed]; Report the isolation of an ATR cDNA, from a bovine liver library, by complementation of an ATR-deficient Salmonella mutant., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q2NL20", "ec_number_list": "2.5.1.-", "go_molecular_function": "GO:0005524 ATP binding;GO:0031419 cobalamin binding;GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups;GO:0008817 corrinoid adenosyltransferase activity", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0009235 cobalamin metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q58D49-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q58D85-1", "uniprot_id": "PAR3_BOVIN", "mass": 43009.0, "length": 377, "protein_name": "Proteinase-activated receptor 3", "gene_name": "F2RL2", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "F2RL2; PAR3", "gene_names_refseq": "", "protein_names_uniprotkb": "Proteinase-activated receptor 3; Coagulation factor II receptor-like 2; PAR-3; Thrombin receptor-like 2", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "Receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0015057 thrombin-activated receptor activity;GO:0004930 G protein-coupled receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway;GO:0007596 blood coagulation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q58D85-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q58D94-1", "uniprot_id": "MKNK1_BOVIN", "mass": 46700.0, "length": 420, "protein_name": "MAP kinase-interacting serine/threonine-protein kinase 1", "gene_name": "MKNK1", "organism": "Bovine", "refseq_name": "MAP kinase-interacting serine/threonine-protein kinase 1", "refseq_ac": "NP_001030435", "gene_names_uniprotkb": "MKNK1", "gene_names_refseq": "MKNK1", "protein_names_uniprotkb": "MAP kinase-interacting serine/threonine-protein kinase 1; 2.7.11.1; MAP kinase signal-integrating kinase 1; MAPK signal-integrating kinase 1; Mnk1", "protein_names_refseq": "MAP kinase interacting serine/threonine kinase 1; MAP kinase signal-integrating kinase 1; MAP kinase-interacting serine/threonine-protein kinase 1; MAPK signal-integrating kinase 1; mnk1", "tax_id": 9913, "disease": "", "pathway": " (bta:525647)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "May play a role in the response to environmental stress and cytokines. Appears to regulate translation by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA cap (By similarity)., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q2T9R8", "ec_number_list": "2.7.11.1;2.7.11.25;2.7.11.24;2.7.11.22;2.7.11.13;2.7.11.23;2.7.12.1;2.7.12.2;2.7.11.17;2.7.11.39;2.7.10.2;2.7.1.150;2.7.11.12;2.7.11.31;2.7.11.26;2.7.11.21;2.7.1.153;2.7.1.137;2.7.1.154;4.1.1.32;2.7.11.38;2.7.11.11;3.1.11.-;2.7.4.6;2.7.13.3;2.7.4.18;3.1.24.-;2.7.11.-;2.7.11.4;2.7.2.3;2.7.11.10", "go_molecular_function": "GO:0009931 calcium-dependent protein serine/threonine kinase activity;GO:0005516 calmodulin binding;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0004683 calcium/calmodulin-dependent protein kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006417 regulation of translation;GO:0035556 intracellular signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q58D94-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q58DA1-1", "uniprot_id": "SPEF1_BOVIN", "mass": 27111.0, "length": 236, "protein_name": "Sperm flagella and cilia-associated protein 1", "gene_name": "SPEF1", "organism": "Bovine", "refseq_name": "sperm flagellar protein 1", "refseq_ac": "NP_001029594", "gene_names_uniprotkb": "SPEF1", "gene_names_refseq": "C20orf28; SPEF1", "protein_names_uniprotkb": "Sperm flagella and cilia-associated protein 1", "protein_names_refseq": "sperm flagellar protein 1", "tax_id": 9913, "disease": "", "pathway": " (bta:512410)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "Microtubule-associated protein involved in the stabilization of microtubules along the axis of migration during radial intercalation. Promotes the establishment and stabilization of an axis of microtubules required for the active migration of cells into the outer epithelium (By similarity). Microtubule-associated protein that promotes microtubule bundling and stabilizes microtubules against depolymerization in response to cold shock (By similarity). Essential for ciliary central apparatus formation which requires both its microtubule-binding and bundling activities and for ciliary localization of HYDIN and SPAG6 in ependymal cilia (By similarity). Binds actin in intestinal epithelial cells (IECs), essential for IECs survival and contributes to formation of filopodia and lamellipodia in migrating IECs (By similarity). Regulates planar cell polarity signaling pathway and asymmetric microtubule accumulation in ciliated epithelia (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003779 actin binding;GO:0008017 microtubule binding", "go_cellular_component": "GO:1990716 axonemal central apparatus;GO:0005737 cytoplasm;GO:0005874 microtubule;GO:0016323 basolateral plasma membrane;GO:0030027 lamellipodium", "go_biological_process": "GO:2000095 regulation of Wnt signaling pathway, planar cell polarity pathway;GO:1904158 axonemal central apparatus assembly;GO:0016477 cell migration;GO:0046847 filopodium assembly;GO:0030032 lamellipodium assembly", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q58DA1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q58DA6-1", "uniprot_id": "S35A2_BOVIN", "mass": 41180.0, "length": 393, "protein_name": "UDP-galactose translocator", "gene_name": "SLC35A2", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "SLC35A2", "gene_names_refseq": "", "protein_names_uniprotkb": "UDP-galactose translocator; Solute carrier family 35 member A2; UDP-Gal-Tr; UDP-galactose transporter; UGT", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "Transports uridine diphosphate galactose (UDP-galactose) from the cytosol into the Golgi apparatus, functioning as an antiporter that exchanges UDP-galactose for UMP. It is also able to exchange UDP-galactose for AMP and CMP, and to transport UDP-N-acetylgalactosamine (UDP-GalNAc) and other nucleotide sugars. As a provider of UDP-galactose to galactosyltransferases present in the Golgi apparatus, it is necessary for globotriaosylceramide/globoside (Gb3Cer) synthesis from lactosylceramide., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0015297 antiporter activity;GO:0005459 UDP-galactose transmembrane transporter activity", "go_cellular_component": "GO:0000139 Golgi membrane", "go_biological_process": "GO:0072334 UDP-galactose transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q58DA6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q58DA7-1", "uniprot_id": "GLRX3_BOVIN", "mass": 37298.0, "length": 334, "protein_name": "Glutaredoxin-3", "gene_name": "GLRX3", "organism": "Bovine", "refseq_name": "glutaredoxin-3", "refseq_ac": "NP_001030273", "gene_names_uniprotkb": "GLRX3; TXNL2", "gene_names_refseq": "GLRX3; PICOT; TXNL2", "protein_names_uniprotkb": "Glutaredoxin-3; PICOT; PKC-interacting cousin of thioredoxin; Thioredoxin-like protein 2", "protein_names_refseq": "PKC-interacting cousin of thioredoxin; glutaredoxin-3; thioredoxin-like protein 2", "tax_id": 9913, "disease": "", "pathway": " (bta:511528)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "Together with BOLA2, acts as a cytosolic iron-sulfur (Fe-S) cluster assembly factor that facilitates [2Fe-2S] cluster insertion into a subset of cytosolic proteins (By similarity). Acts as a critical negative regulator of cardiac hypertrophy and a positive inotropic regulator (By similarity). Required for hemoglobin maturation. Does not possess any thioredoxin activity since it lacks the conserved motif that is essential for catalytic activity (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A3KMZ2", "ec_number_list": "", "go_molecular_function": "GO:0046872 metal ion binding;GO:0051536 iron-sulfur cluster binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0005938 cell cortex;GO:0030018 Z disc", "go_biological_process": "GO:0006879 intracellular iron ion homeostasis;GO:0002026 regulation of the force of heart contraction;GO:0010614 negative regulation of cardiac muscle hypertrophy", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q58DA7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q58DA8-1", "uniprot_id": "ZDHC9_BOVIN", "mass": 40826.0, "length": 363, "protein_name": "Palmitoyltransferase ZDHHC9", "gene_name": "ZDHHC9", "organism": "Bovine", "refseq_name": "palmitoyltransferase ZDHHC9", "refseq_ac": "NP_001029733", "gene_names_uniprotkb": "ZDHHC9", "gene_names_refseq": "ZDHHC9", "protein_names_uniprotkb": "Palmitoyltransferase ZDHHC9; 2.3.1.225; DHHC-9; Zinc finger DHHC domain-containing protein 9", "protein_names_refseq": "DHHC-9; palmitoyltransferase ZDHHC9; zinc finger DHHC domain-containing protein 9; zinc finger DHHC-type containing 9; zinc finger, DHHC domain containing 9", "tax_id": 9913, "disease": "", "pathway": " (bta:527885); (R-BTA-9648002)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "Palmitoyltransferase that catalyzes the addition of palmitate onto various protein substrates, such as ADRB2, GSDMD, HRAS, NRAS and CGAS. The ZDHHC9-GOLGA7 complex is a palmitoyltransferase specific for HRAS and NRAS. May have a palmitoyltransferase activity toward the beta-2 adrenergic receptor/ADRB2 and therefore regulate G protein-coupled receptor signaling. Acts as a regulator of innate immunity by catalyzing palmitoylation of CGAS, thereby promoting CGAS homodimerization and cyclic GMP-AMP synthase activity. Activates pyroptosis by catalyzing palmitoylation of gasdermin-D (GSDMD), thereby promoting membrane translocation and pore formation of GSDMD., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q2KJI5", "ec_number_list": "3.6.5.2;2.3.1.225;6.3.1.2;2.3.1.-", "go_molecular_function": "GO:0019706 protein-cysteine S-palmitoyltransferase activity;GO:0043849 Ras palmitoyltransferase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0005789 endoplasmic reticulum membrane;GO:0002178 palmitoyltransferase complex", "go_biological_process": "GO:0043687 post-translational protein modification;GO:0006612 protein targeting to membrane;GO:0140639 positive regulation of pyroptotic inflammatory response", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q58DA8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q58DH9-1", "uniprot_id": "NAGAB_BOVIN", "mass": 46533.0, "length": 411, "protein_name": "Alpha-N-acetylgalactosaminidase", "gene_name": "NAGA", "organism": "Bovine", "refseq_name": "alpha-N-acetylgalactosaminidase precursor", "refseq_ac": "NP_001039814", "gene_names_uniprotkb": "NAGA", "gene_names_refseq": "NAGA", "protein_names_uniprotkb": "Alpha-N-acetylgalactosaminidase; 3.2.1.49; Alpha-galactosidase B", "protein_names_refseq": "N-acetylgalactosaminidase, alpha-; alpha-N-acetylgalactosaminidase precursor; alpha-galactosidase B", "tax_id": 9913, "disease": "", "pathway": " (bta:533357)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "Removes terminal alpha-N-acetylgalactosamine residues from glycolipids and glycopeptides. Required for the breakdown of glycolipids., [UniProtKB, UniProtKB]", "predicted_glycosites": 5, "predicted_n_glycosites": 5, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.2.1.-;3.2.1.49", "go_molecular_function": "GO:0004557 alpha-galactosidase activity;GO:0008456 alpha-N-acetylgalactosaminidase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0016020 membrane;GO:0005764 lysosome", "go_biological_process": "GO:0019377 glycolipid catabolic process;GO:0016052 carbohydrate catabolic process;GO:0009311 oligosaccharide metabolic process;GO:0016139 glycoside catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q58DH9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q58DJ0-1", "uniprot_id": "IRF5_BOVIN", "mass": 55931.0, "length": 499, "protein_name": "Interferon regulatory factor 5", "gene_name": "IRF5", "organism": "Bovine", "refseq_name": "interferon regulatory factor 5", "refseq_ac": "NP_001030542", "gene_names_uniprotkb": "IRF5", "gene_names_refseq": "IRF5", "protein_names_uniprotkb": "Interferon regulatory factor 5; IRF-5", "protein_names_refseq": "IRF-5; interferon regulatory factor 5", "tax_id": 9913, "disease": "", "pathway": " (bta:615340)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "Transcription factor that plays a critical role in innate immunity by activating expression of type I interferon (IFN) IFNA and INFB and inflammatory cytokines downstream of endolysosomal toll-like receptors TLR7, TLR8 and TLR9. Regulates the transcription of type I IFN genes (IFN-alpha and IFN-beta) and IFN-stimulated genes (ISG) by binding to an interferon-stimulated response element (ISRE) in their promoters. Can efficiently activate both the IFN-beta (IFNB) and the IFN-alpha (IFNA) genes and mediate their induction downstream of the TLR-activated, MyD88-dependent pathway., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 9, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0006954 inflammatory response;GO:0045087 innate immune response;GO:0045944 positive regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q58DJ0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q58DK4-1", "uniprot_id": "TKFC_BOVIN", "mass": 59124.0, "length": 578, "protein_name": "Triokinase/FMN cyclase", "gene_name": "TKFC", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "TKFC; DAK", "gene_names_refseq": "", "protein_names_uniprotkb": "Triokinase/FMN cyclase; Bifunctional ATP-dependent dihydroxyacetone kinase/FAD-AMP lyase (cyclizing); FAD-AMP lyase (cyclic FMN forming); FMN cyclase; Glycerone kinase; Triokinase; Triose kinase", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "Catalyzes both the phosphorylation of dihydroxyacetone and of glyceraldehyde, and the splitting of ribonucleoside diphosphate-X compounds among which FAD is the best substrate. Represses IFIH1-mediated cellular antiviral response., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.1.28;2.7.1.29;4.6.1.15", "go_molecular_function": "GO:0004371 glycerone kinase activity;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0034012 FAD-AMP lyase (cyclizing) activity;GO:0050354 triokinase activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0019563 glycerol catabolic process;GO:0039534 negative regulation of MDA-5 signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q58DK4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q58DK5-1", "uniprot_id": "HEM2_BOVIN", "mass": 36081.0, "length": 329, "protein_name": "Delta-aminolevulinic acid dehydratase", "gene_name": "ALAD", "organism": "Bovine", "refseq_name": "delta-aminolevulinic acid dehydratase", "refseq_ac": "NP_001014895", "gene_names_uniprotkb": "ALAD", "gene_names_refseq": "ALAD", "protein_names_uniprotkb": "Delta-aminolevulinic acid dehydratase; 4.2.1.24; ALADH; Porphobilinogen synthase", "protein_names_refseq": "ALADH; aminolevulinate, delta-, dehydratase; delta-aminolevulinic acid dehydratase; porphobilinogen synthase", "tax_id": 9913, "disease": "", "pathway": " (bta:510679); (R-BTA-189451); (R-BTA-6798695)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.1.1.42;2.5.1.18;2.7.1.1;2.7.11.24;3.2.1.23;2.4.2.1;5.2.1.8;4.1.2.13;3.6.1.6;2.3.2.27;3.1.6.14;3.6.4.13;1.1.1.205;2.7.1.11;2.7.11.22;2.7.11.23;2.3.2.26;2.4.1.25;3.2.1.33;4.2.99.18;5.6.2.4;3.6.4.12;3.4.23.5;1.13.11.34;1.13.11.12;3.6.4.6;1.16.3.1;1.11.1.6;3.4.18.1;3.4.22.1;3.6.4.10;3.4.22.27;3.4.24.35;3.6.5.-;3.1.1.47;5.3.2.1;5.3.3.12;3.4.19.1;2.7.1.35;2.4.1.1;3.5.1.23;3.5.1.-;3.4.22.52;2.3.3.8;5.4.2.11;5.4.2.4;3.3.2.6;3.4.11.4;3.4.21.46;2.7.4.6;2.7.13.3;4.1.2.4;5.3.1.9;5.1.3.-;3.6.1.-;2.4.2.7;4.2.1.24", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0042802 identical protein binding;GO:0004655 porphobilinogen synthase activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0051260 protein homooligomerization;GO:0006783 heme biosynthetic process;GO:0006782 protoporphyrinogen IX biosynthetic process;GO:1901799 negative regulation of proteasomal protein catabolic process;GO:0006784 heme A biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q58DK5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q58DK8-1", "uniprot_id": "TRI38_BOVIN", "mass": 52990.0, "length": 460, "protein_name": "E3 ubiquitin-protein ligase TRIM38", "gene_name": "TRIM38", "organism": "Bovine", "refseq_name": "E3 ubiquitin-protein ligase TRIM38", "refseq_ac": "NP_001029746", "gene_names_uniprotkb": "TRIM38", "gene_names_refseq": "TRIM38", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase TRIM38; 2.3.2.27; Tripartite motif-containing protein 38", "protein_names_refseq": "E3 ubiquitin-protein ligase TRIM38; RING-type E3 ubiquitin transferase TRIM38; tripartite motif-containing protein 38", "tax_id": 9913, "disease": "", "pathway": " (bta:531022)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "E3 ubiquitin-protein and E3 SUMO-protein ligase that acts as a regulator of innate immunity. Acts as a negative regulator of type I interferon IFN-beta production by catalyzing 'Lys-48'-linked polyubiquitination of AZI2/NAP1, leading to its degradation. Mediates 'Lys-48'-linked polyubiquitination and proteasomal degradation of the critical TLR adapter TICAM1, inhibiting TLR3-mediated type I interferon signaling. Acts as a positive regulator of the cGAS-STING pathway by acting as a E3 SUMO-protein ligase: mediates sumoylation of CGAS and STING, preventing their degradation and thereby activating the innate immune response to DNA virus (By similarity). Also acts as a negative regulator of NF-kappa-B signaling independently of its E3 protein ligase activity by promoting lysosome-dependent degradation of TAB2 and TAB3 adapters (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003713 transcription coactivator activity;GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0046596 regulation of viral entry into host cell;GO:0016925 protein sumoylation;GO:0045087 innate immune response;GO:0043123 positive regulation of canonical NF-kappaB signal transduction;GO:0046598 positive regulation of viral entry into host cell", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q58DK8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q58DL5-1", "uniprot_id": "BCAR3_BOVIN", "mass": 92765.0, "length": 826, "protein_name": "Breast cancer anti-estrogen resistance protein 3 homolog", "gene_name": "BCAR3", "organism": "Bovine", "refseq_name": "breast cancer anti-estrogen resistance protein 3 homolog", "refseq_ac": "NP_001019654", "gene_names_uniprotkb": "BCAR3", "gene_names_refseq": "BCAR3", "protein_names_uniprotkb": "Breast cancer anti-estrogen resistance protein 3 homolog", "protein_names_refseq": "BCAR3, NSP family adaptor protein; breast cancer anti-estrogen resistance 3; breast cancer anti-estrogen resistance protein 3 homolog; breast cancer antiestrogen resistance 3", "tax_id": 9913, "disease": "", "pathway": " (bta:506231)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "Acts as an adapter protein downstream of several growth factor receptors to promote cell proliferation, migration, and redistribution of actin fibers (By similarity). Specifically involved in INS/insulin signaling pathway by mediating MAPK1/ERK2-MAPK3/ERK1 activation and DNA synthesis (By similarity). Promotes insulin-mediated membrane ruffling (By similarity). In response to vasoconstrictor peptide EDN1, involved in the activation of RAP1 downstream of PTK2B via interaction with phosphorylated BCAR1. Inhibits cell migration and invasion via regulation of TGFB-mediated matrix digestion, actin filament rearrangement, and inhibition of invadopodia activity. May inhibit TGFB-SMAD signaling, via facilitating BCAR1 and SMAD2 and/or SMAD3 interaction (By similarity). Regulates EGF-induced DNA synthesis (By similarity). Required for the maintenance of ocular lens morphology and structural integrity, potentially via regulation of focal adhesion complex signaling. Acts upstream of PTPRA to regulate the localization of BCAR1 and PTPRA to focal adhesions, via regulation of SRC-mediated phosphorylation of PTPRA. Positively regulates integrin-induced tyrosine phosphorylation of BCAR1. Acts as a guanine nucleotide exchange factor (GEF) for small GTPases RALA, RAP1A and RRAS (By similarity). However, in a contrasting study, lacks GEF activity towards RAP1 (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 9, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q2KJF5", "ec_number_list": "", "go_molecular_function": "GO:0001784 phosphotyrosine residue binding;GO:0005085 guanyl-nucleotide exchange factor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005925 focal adhesion;GO:0016020 membrane", "go_biological_process": "GO:0086100 endothelin receptor signaling pathway;GO:0008284 positive regulation of cell population proliferation;GO:0043410 positive regulation of MAPK cascade;GO:0043547 positive regulation of GTPase activity;GO:0007173 epidermal growth factor receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q58DL5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q58DR8-1", "uniprot_id": "SUCA_BOVIN", "mass": 36167.0, "length": 346, "protein_name": "Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial", "gene_name": "SUCLG1", "organism": "Bovine", "refseq_name": "succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial precursor", "refseq_ac": "NP_001030254", "gene_names_uniprotkb": "SUCLG1", "gene_names_refseq": "SUCLG1", "protein_names_uniprotkb": "Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; 6.2.1.-; 6.2.1.4; 6.2.1.5; 6.2.1.9; Itaconyl--CoA ligase [ADP/GDP-forming] subunit alpha; Malyl--CoA ligase [ADP/GDP-forming] subunit alpha; SCS-alpha; Succinyl-CoA synthetase subunit alpha", "protein_names_refseq": "SCS-alpha; itaconyl--CoA ligase [ADP/GDP-forming] subunit alpha; malyl--CoA ligase [ADP/GDP-forming] subunit alpha; succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial precursor; succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; succinate-CoA ligase alpha subunit; succinate-CoA ligase, GDP-forming alpha subunit; succinyl-CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; succinyl-CoA ligase [GDP-forming] subunit alpha, mitochondrial; succinyl-CoA synthetase subunit alpha", "tax_id": 9913, "disease": "", "pathway": " (bta:509983)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. Also able to act as an itaconyl- and malyl-CoA synthetase., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "6.2.1.4;6.2.1.5;6.2.1.-;6.2.1.9", "go_molecular_function": "GO:0000166 nucleotide binding;GO:0004775 succinate-CoA ligase (ADP-forming) activity;GO:0004776 succinate-CoA ligase (GDP-forming) activity;GO:0050074 malate-CoA ligase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0045244 succinate-CoA ligase complex (GDP-forming);GO:0009361 succinate-CoA ligase complex (ADP-forming)", "go_biological_process": "GO:0006099 tricarboxylic acid cycle", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q58DR8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q58DS9-1", "uniprot_id": "RAB5C_BOVIN", "mass": 23467.0, "length": 216, "protein_name": "Ras-related protein Rab-5C", "gene_name": "RAB5C", "organism": "Bovine", "refseq_name": "ras-related protein Rab-5C", "refseq_ac": "NP_001029915", "gene_names_uniprotkb": "RAB5C", "gene_names_refseq": "RAB5B; RAB5C", "protein_names_uniprotkb": "Ras-related protein Rab-5C; 3.6.5.2", "protein_names_refseq": "RAB5B, member RAS oncogene family; ras-related protein Rab-5C", "tax_id": 9913, "disease": "", "pathway": " (bta:613749)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. Involved in early endocytic trafficking. Required for EEA1 recruitment to early endosomes. Required for EGF and transferrin endocytosis and trafficking through early endosomes., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q17QR1", "ec_number_list": "3.6.5.2;3.6.5.5;3.6.5.-;3.6.5.3;2.7.11.1;3.6.1.5;3.6.1.15;3.6.5.4", "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0046872 metal ion binding;GO:0019003 GDP binding;GO:0003925 G protein activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0042470 melanosome;GO:0031901 early endosome membrane", "go_biological_process": "GO:0006897 endocytosis;GO:0015031 protein transport;GO:0016197 endosomal transport;GO:0016192 vesicle-mediated transport;GO:0048227 plasma membrane to endosome transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q58DS9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q58DW2-1", "uniprot_id": "CGL_BOVIN", "mass": 44406.0, "length": 405, "protein_name": "Cystathionine gamma-lyase", "gene_name": "CTH", "organism": "Bovine", "refseq_name": "cystathionine gamma-lyase", "refseq_ac": "NP_001019738", "gene_names_uniprotkb": "CTH", "gene_names_refseq": "CTH", "protein_names_uniprotkb": "Cystathionine gamma-lyase; 4.4.1.1; Cysteine-protein sulfhydrase; Gamma-cystathionase", "protein_names_refseq": "cystathionase (cystathionine gamma-lyase); cystathionine gamma-lyase; cysteine-protein sulfhydrase; gamma-cystathionase", "tax_id": 9913, "disease": "", "pathway": " (bta:539159)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "16305752;34769192", "class_list": "", "function": "Catalyzes the last step in the trans-sulfuration pathway from methionine to cysteine. Has broad substrate specificity. Converts cystathionine to cysteine, ammonia and 2-oxobutanoate. Converts two cysteine molecules to lanthionine and hydrogen sulfide. Can also accept homocysteine as substrate. Specificity depends on the levels of the endogenous substrates. Generates the endogenous signaling molecule hydrogen sulfide (H2S), and so contributes to the regulation of blood pressure. Acts as a cysteine-protein sulfhydrase by mediating sulfhydration of target proteins: sulfhydration consists of converting -SH groups into -SSH on specific cysteine residues of target proteins such as GAPDH, PTPN1 and NF-kappa-B subunit RELA, thereby regulating their function (By similarity)., [UniProtKB]; Synthesis of Reactive Sulfur Species in Cultured Vascular Endothelial Cells after Exposure to TGF-beta1: Induction of Cystathionine gamma-Lyase and Cystathionine beta-Synthase Expression Mediated by the ALK5-Smad2/3/4 and ALK5-Smad2/3-ATF4 Pathways. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "4.4.1.1;4.4.1.2", "go_molecular_function": "GO:0005516 calmodulin binding;GO:0030170 pyridoxal phosphate binding;GO:0004123 cystathionine gamma-lyase activity;GO:0044540 L-cystine L-cysteine-lyase (deaminating)", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0006629 lipid metabolic process;GO:0043066 negative regulation of apoptotic process;GO:0043123 positive regulation of canonical NF-kappaB signal transduction;GO:0019346 transsulfuration;GO:0019343 cysteine biosynthetic process via cystathionine", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q58DW2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q58DW6-1", "uniprot_id": "RAB25_BOVIN", "mass": 23537.0, "length": 213, "protein_name": "Ras-related protein Rab-25", "gene_name": "RAB25", "organism": "Bovine", "refseq_name": "ras-related protein Rab-25", "refseq_ac": "NP_001017936", "gene_names_uniprotkb": "RAB25", "gene_names_refseq": "RAB25", "protein_names_uniprotkb": "Ras-related protein Rab-25; 3.6.5.2", "protein_names_refseq": "ras-related protein Rab-25", "tax_id": 9913, "disease": "", "pathway": " (bta:506482); (R-BTA-8873719)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion (By similarity). RAB25 regulates epithelial cell differentiation, proliferation and survival, thereby playing key roles in tumorigenesis. Promotes invasive migration of cells in which it functions to localize and maintain integrin alpha-V/beta-1 at the tips of extending pseudopodia (By similarity). Involved in the regulation of epithelial morphogenesis through the control of CLDN4 expression and localization at tight junctions (By similarity). May selectively regulate the apical recycling pathway (By similarity). Together with MYO5B regulates transcytosis (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q0VCM9", "ec_number_list": "3.6.5.2;3.6.5.5;3.6.5.-;3.6.5.3;2.7.11.1;3.6.1.5;3.6.1.15;3.6.5.4;2.5.1.60", "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0046872 metal ion binding;GO:0031489 myosin V binding;GO:0003925 G protein activity", "go_cellular_component": "GO:0031260 pseudopodium membrane;GO:0005794 Golgi apparatus;GO:0055037 recycling endosome;GO:0031410 cytoplasmic vesicle;GO:0031143 pseudopodium", "go_biological_process": "GO:0031268 pseudopodium organization;GO:0008284 positive regulation of cell population proliferation;GO:0015031 protein transport;GO:0060627 regulation of vesicle-mediated transport;GO:0003382 epithelial cell morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q58DW6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q5BIN2-1", "uniprot_id": "SNF5_BOVIN", "mass": 44111.0, "length": 385, "protein_name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1", "gene_name": "SMARCB1", "organism": "Bovine", "refseq_name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1", "refseq_ac": "NP_001035647", "gene_names_uniprotkb": "SMARCB1; BAF47", "gene_names_refseq": "SMARCB1", "protein_names_uniprotkb": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; BAF47; BRG1-associated factor 47", "protein_names_refseq": "BAF47; BRG1-associated factor 47; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1", "tax_id": 9913, "disease": "", "pathway": " (bta:537412); (R-BTA-3214858); (R-BTA-8939243); (R-BTA-9933937); (R-BTA-9933939); (R-BTA-9933946); (R-BTA-9934037)", "pathway_count": 7, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "Core component of the BAF (SWI/SNF) complex. This ATP-dependent chromatin-remodeling complex plays important roles in cell proliferation and differentiation, in cellular antiviral activities and inhibition of tumor formation. The BAF complex is able to create a stable, altered form of chromatin that constrains fewer negative supercoils than normal. This change in supercoiling would be due to the conversion of up to one-half of the nucleosomes on polynucleosomal arrays into asymmetric structures, termed altosomes, each composed of 2 histones octamers. Stimulates in vitro the remodeling activity of SMARCA4/BRG1/BAF190A. Plays a key role in cell-cycle control and causes cell cycle arrest in G0/G1. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a postmitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to postmitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A2VE50", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0003713 transcription coactivator activity;GO:0042802 identical protein binding;GO:0030957 Tat protein binding;GO:0002039 p53 binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0016514 SWI/SNF complex;GO:0071564 npBAF complex;GO:0001650 fibrillar center", "go_biological_process": "GO:1902661 positive regulation of glucose mediated signaling pathway;GO:0006338 chromatin remodeling;GO:0006357 regulation of transcription by RNA polymerase II;GO:0007399 nervous system development;GO:0045944 positive regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q5BIN2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q5E951-1", "uniprot_id": "TBCB_BOVIN", "mass": 27518.0, "length": 244, "protein_name": "Tubulin-folding cofactor B", "gene_name": "TBCB", "organism": "Bovine", "refseq_name": "tubulin-folding cofactor B", "refseq_ac": "NP_001014939", "gene_names_uniprotkb": "TBCB; CKAP1", "gene_names_refseq": "CKAP1; TBCB", "protein_names_uniprotkb": "Tubulin-folding cofactor B; Cytoskeleton-associated protein 1; Cytoskeleton-associated protein CKAPI; Tubulin-specific chaperone B", "protein_names_refseq": "cytoskeleton associated protein 1; cytoskeleton-associated protein CKAPI; tubulin-folding cofactor B; tubulin-specific chaperone B", "tax_id": 9913, "disease": "", "pathway": " (bta:530447)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "Binds to alpha-tubulin folding intermediates after their interaction with cytosolic chaperonin in the pathway leading from newly synthesized tubulin to properly folded heterodimer. Involved in regulation of tubulin heterodimer dissociation. May function as a negative regulator of axonal growth., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q3ZCC1", "ec_number_list": "", "go_molecular_function": "GO:0051010 microtubule plus-end binding;GO:0043014 alpha-tubulin binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005938 cell cortex;GO:0035371 microtubule plus-end", "go_biological_process": "GO:0007399 nervous system development;GO:0030154 cell differentiation;GO:0007021 tubulin complex assembly;GO:0031122 cytoplasmic microtubule organization;GO:0007023 post-chaperonin tubulin folding pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q5E951-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q5E958-1", "uniprot_id": "RS8_BOVIN", "mass": 24205.0, "length": 208, "protein_name": "Small ribosomal subunit protein eS8", "gene_name": "RPS8", "organism": "Bovine", "refseq_name": "small ribosomal subunit protein eS8", "refseq_ac": "NP_001020488", "gene_names_uniprotkb": "RPS8", "gene_names_refseq": "RPS8", "protein_names_uniprotkb": "Small ribosomal subunit protein eS8; 40S ribosomal protein S8", "protein_names_refseq": "40S ribosomal protein S8; small ribosomal subunit protein eS8", "tax_id": 9913, "disease": "", "pathway": " (bta:404140); (R-BTA-156827); (R-BTA-1799339); (R-BTA-6791226); (R-BTA-72649); (R-BTA-72689); (R-BTA-72695); (R-BTA-72702); (R-BTA-72706); (R-BTA-975956); (R-BTA-975957); (R-BTA-9954714); (R-BTA-9954716)", "pathway_count": 13, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "Component of the small ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A1A4S0", "ec_number_list": "", "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0016020 membrane;GO:1990904 ribonucleoprotein complex;GO:0032040 small-subunit processome;GO:0022627 cytosolic small ribosomal subunit", "go_biological_process": "GO:0006412 translation;GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0042274 ribosomal small subunit biogenesis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q5E958-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q5E965-1", "uniprot_id": "C56D2_BOVIN", "mass": 24077.0, "length": 222, "protein_name": "Transmembrane reductase CYB561D2", "gene_name": "CYB561D2", "organism": "Bovine", "refseq_name": "transmembrane reductase CYB561D2", "refseq_ac": "NP_001014937", "gene_names_uniprotkb": "CYB561D2", "gene_names_refseq": "CYB561D2", "protein_names_uniprotkb": "Transmembrane reductase CYB561D2; 7.2.1.3; Cytochrome b561 domain-containing protein 2", "protein_names_refseq": "cytochrome b-561 domain containing 2; cytochrome b561 domain-containing protein 2; putative tumor suppressor protein 101F6; transmembrane ascorbate ferrireductase; transmembrane reductase CYB561D2", "tax_id": 9913, "disease": "", "pathway": " (bta:523966)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "Transmembrane reductase that may use ascorbate as an electron donor in the cytoplasm and transfer electrons across endoplasmic reticulum membranes to reduce monodehydro-L-ascorbate radical and iron cations Fe(3+) in the lumen of that compartment., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q29S15", "ec_number_list": "7.2.1.3", "go_molecular_function": "GO:0046872 metal ion binding;GO:0020037 heme binding;GO:0140575 transmembrane monodehydroascorbate reductase activity;GO:0140571 transmembrane ascorbate ferrireductase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane;GO:0030659 cytoplasmic vesicle membrane;GO:0031982 vesicle", "go_biological_process": "GO:0140576 ascorbate homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q5E965-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q5E968-1", "uniprot_id": "CATK_BOVIN", "mass": 36947.0, "length": 329, "protein_name": "Cathepsin K", "gene_name": "CTSK", "organism": "Bovine", "refseq_name": "cathepsin K precursor", "refseq_ac": "NP_001029607", "gene_names_uniprotkb": "CTSK", "gene_names_refseq": "CTSK", "protein_names_uniprotkb": "Cathepsin K; 3.4.22.38", "protein_names_refseq": "cathepsin K precursor; cathepsin K preproprotein", "tax_id": 9913, "disease": "", "pathway": " (bta:513038); (R-BTA-1442490); (R-BTA-1474228); (R-BTA-1592389); (R-BTA-1679131); (R-BTA-2132295); (R-BTA-8939242)", "pathway_count": 7, "publication_count": 2, "publication_id_list": "16305752;32224503", "class_list": "", "function": "Inverse relationship between autophagy and CTSK is related to bovine embryo quality., [RefSeq, PubMed]; Thiol protease involved in osteoclastic bone resorption and may participate partially in the disorder of bone remodeling. Displays potent endoprotease activity against fibrinogen at acid pH. May play an important role in extracellular matrix degradation. Involved in the release of thyroid hormone thyroxine (T4) by limited proteolysis of TG/thyroglobulin in the thyroid follicle lumen., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.4.22.34;3.4.23.5;3.4.24.17;3.4.22.1;3.4.22.27;3.4.22.15;3.4.24.35;3.4.16.5;3.4.16.-;3.4.22.38", "go_molecular_function": "GO:0004197 cysteine-type endopeptidase activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005764 lysosome;GO:0016324 apical plasma membrane", "go_biological_process": "GO:0051603 proteolysis involved in protein catabolic process;GO:0006590 thyroid hormone generation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q5E968-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q5E995-1", "uniprot_id": "RS6_BOVIN", "mass": 28667.0, "length": 249, "protein_name": "Small ribosomal subunit protein eS6", "gene_name": "RPS6", "organism": "Bovine", "refseq_name": "small ribosomal subunit protein eS6", "refseq_ac": "NP_001015548", "gene_names_uniprotkb": "RPS6", "gene_names_refseq": "RPS6", "protein_names_uniprotkb": "Small ribosomal subunit protein eS6; 40S ribosomal protein S6", "protein_names_refseq": "40S ribosomal protein S6; small ribosomal subunit protein eS6", "tax_id": 9913, "disease": "", "pathway": " (bta:787914); (R-BTA-156827); (R-BTA-166208); (R-BTA-1799339); (R-BTA-6791226); (R-BTA-72649); (R-BTA-72689); (R-BTA-72695); (R-BTA-72702); (R-BTA-72706); (R-BTA-9629569); (R-BTA-975956); (R-BTA-975957); (R-BTA-9954714); (R-BTA-9954716)", "pathway_count": 15, "publication_count": 2, "publication_id_list": "16305752;25281768", "class_list": "", "function": "Component of the 40S small ribosomal subunit. Plays an important role in controlling cell growth and proliferation through the selective translation of particular classes of mRNA. Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome., [UniProtKB, UniProtKB]; Molecular network including eIF1AX, RPS7, and 14-3-3gamma regulates protein translation and cell proliferation in BMECs., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 7, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005634 nucleus;GO:0048471 perinuclear region of cytoplasm;GO:0032040 small-subunit processome;GO:0022627 cytosolic small ribosomal subunit", "go_biological_process": "GO:0008284 positive regulation of cell population proliferation;GO:0042593 glucose homeostasis;GO:0002181 cytoplasmic translation;GO:0042274 ribosomal small subunit biogenesis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q5E995-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q5E9B2-1", "uniprot_id": "PAF15_BOVIN", "mass": 11910.0, "length": 111, "protein_name": "PCNA-associated factor", "gene_name": "PCLAF", "organism": "Bovine", "refseq_name": "PCNA-associated factor", "refseq_ac": "NP_001015678", "gene_names_uniprotkb": "PCLAF; PAF", "gene_names_refseq": "PAF15; PAF; PCLAF", "protein_names_uniprotkb": "PCNA-associated factor; PAF15; PCNA-associated factor of 15 kDa; PCNA-clamp-associated factor; p15PAF", "protein_names_refseq": "PCNA-associated factor of 15 kDa; PCNA-associated factor; p15PAF", "tax_id": 9913, "disease": "", "pathway": " (bta:540737); (R-BTA-5656169)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "PCNA-binding protein that acts as a regulator of DNA repair during DNA replication. Following DNA damage, the interaction with PCNA is disrupted, facilitating the interaction between monoubiquitinated PCNA and the translesion DNA synthesis DNA polymerase eta (POLH) at stalled replisomes, facilitating the bypass of replication-fork-blocking lesions. Also acts as a regulator of centrosome number (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003682 chromatin binding", "go_cellular_component": "GO:0005634 nucleus;GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "GO:0006281 DNA repair;GO:0006260 DNA replication;GO:0006974 DNA damage response;GO:0009411 response to UV;GO:0007098 centrosome cycle", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q5E9B2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q5E9B8-1", "uniprot_id": "RPB7_BOVIN", "mass": 19294.0, "length": 172, "protein_name": "DNA-directed RNA polymerase II subunit RPB7", "gene_name": "POLR2G", "organism": "Bovine", "refseq_name": "DNA-directed RNA polymerase II subunit RPB7", "refseq_ac": "NP_001015633", "gene_names_uniprotkb": "POLR2G", "gene_names_refseq": "POLR2G", "protein_names_uniprotkb": "DNA-directed RNA polymerase II subunit RPB7; DNA-directed RNA polymerase II subunit G; RNA polymerase II subunit B7", "protein_names_refseq": "DNA-directed RNA polymerase II subunit G; DNA-directed RNA polymerase II subunit RPB7; RNA polymerase II subunit B7; polymerase (RNA) II (DNA directed) polypeptide G", "tax_id": 9913, "disease": "", "pathway": " (bta:526320); (R-BTA-112382); (R-BTA-113418); (R-BTA-5578749); (R-BTA-674695); (R-BTA-6781823); (R-BTA-6782135); (R-BTA-6782210); (R-BTA-6796648); (R-BTA-6803529); (R-BTA-6807505); (R-BTA-72086); (R-BTA-72163); (R-BTA-72165); (R-BTA-72203); (R-BTA-73776); (R-BTA-73779); (R-BTA-75953); (R-BTA-75955); (R-BTA-76042); (R-BTA-77075); (R-BTA-9018519); (R-BTA-9770562)", "pathway_count": 23, "publication_count": 4, "publication_id_list": "16305752;16769904;26789250;28892040", "class_list": "", "function": "Core component of RNA polymerase II (Pol II), a DNA-dependent RNA polymerase which synthesizes mRNA precursors and many functional non-coding RNAs using the four ribonucleoside triphosphates as substrates. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. POLR2G/RPB7 is part of a subcomplex with POLR2D/RPB4 that binds to a pocket formed by POLR2A/RPB1, POLR2B/RPB2 and POLR2F/RPABC2 at the base of the clamp element. The POLR2D/RPB4-POLR2G/RPB7 subcomplex seems to lock the clamp via POLR2G/RPB7 in the closed conformation thus preventing double-stranded DNA to enter the active site cleft. The POLR2D/RPB4-POLR2G/RPB7 subcomplex binds single-stranded DNA and RNA., [UniProtKB, PubMed, PubMed, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003727 single-stranded RNA binding;GO:0003697 single-stranded DNA binding;GO:0031369 translation initiation factor binding", "go_cellular_component": "GO:0005634 nucleus;GO:0000932 P-body;GO:0005665 RNA polymerase II, core complex", "go_biological_process": "GO:0006366 transcription by RNA polymerase II;GO:0006367 transcription initiation at RNA polymerase II promoter;GO:0000956 nuclear-transcribed mRNA catabolic process;GO:0060213 positive regulation of nuclear-transcribed mRNA poly(A) tail shortening;GO:0045948 positive regulation of translational initiation", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q5E9B8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q5E9E2-1", "uniprot_id": "MYL9_BOVIN", "mass": 19865.0, "length": 172, "protein_name": "Myosin regulatory light polypeptide 9", "gene_name": "MYL12A; MYL9", "organism": "Bovine", "refseq_name": "myosin regulatory light polypeptide 9", "refseq_ac": "NP_001015640", "gene_names_uniprotkb": "MYL12A; MYL9; MYRL2", "gene_names_refseq": "MRCL3; MRLC2; MYL12A; MYL9", "protein_names_uniprotkb": "Myosin regulatory light polypeptide 9; Myosin regulatory light chain 2, smooth muscle isoform; Myosin regulatory light chain 9", "protein_names_refseq": "fast skeletal myosin light chain 2; myosin regulatory light chain 9; myosin regulatory light chain MRCL3; myosin regulatory light polypeptide 9", "tax_id": 9913, "disease": "", "pathway": " (bta:531505); (R-BTA-3928664); (R-BTA-445355)", "pathway_count": 3, "publication_count": 3, "publication_id_list": "16055445;16305752;16855019", "class_list": "", "function": "Myosin II may ordinarily move anteriorly on actin filaments and pull crossed filaments into antiparallel bundles, with the resulting realignment pulling the cell body forward., [RefSeq, PubMed]; Myosin phosphatase and cofilin mediate cAMP/cAMP-dependent protein kinase-induced decline in endothelial cell isometric tension and myosin II regulatory light chain phosphorylation, [RefSeq, PubMed]; Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Implicated in cytokinesis, receptor capping, and cell locomotion (By similarity). In myoblasts, may regulate PIEZO1-dependent cortical actomyosin assembly involved in myotube formation (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005509 calcium ion binding;GO:0032036 myosin heavy chain binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005938 cell cortex;GO:0042641 actomyosin;GO:0097513 myosin II filament;GO:0016460 myosin II complex", "go_biological_process": "GO:0031032 actomyosin structure organization", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q5E9E2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q5E9F7-1", "uniprot_id": "COF1_BOVIN", "mass": 18519.0, "length": 166, "protein_name": "Cofilin-1", "gene_name": "CFL1", "organism": "Bovine", "refseq_name": "cofilin-1", "refseq_ac": "NP_001015655", "gene_names_uniprotkb": "CFL1", "gene_names_refseq": "CFL1", "protein_names_uniprotkb": "Cofilin-1; Cofilin, non-muscle isoform", "protein_names_refseq": "cofilin 1 (non-muscle); cofilin-1", "tax_id": 9913, "disease": "", "pathway": " (bta:534553)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "16055445;16305752;17662250;32459556", "class_list": "", "function": "Binds to F-actin and exhibits pH-sensitive F-actin depolymerizing activity (By similarity). Important for normal progress through mitosis and normal cytokinesis (By similarity). In conjunction with the subcortical maternal complex (SCMC), plays an essential role for zygotes to progress beyond the first embryonic cell divisions via regulation of actin dynamics (By similarity). Required for the centralization of the mitotic spindle and symmetric division of zygotes (By similarity). Plays a role in the regulation of cell morphology and cytoskeletal organization in epithelial cells (By similarity). Required for the up-regulation of atypical chemokine receptor ACKR2 from endosomal compartment to cell membrane, increasing its efficiency in chemokine uptake and degradation (By similarity). Required for neural tube morphogenesis and neural crest cell migration (By similarity)., [UniProtKB, UniProtKB, UniProtKB]; Cyclic compression for 10 min up-regulated gene expression for the actin depolymerising proteins, cofilin and destrin., [RefSeq, PubMed]; Myosin phosphatase and cofilin mediate cAMP/cAMP-dependent protein kinase-induced decline in endothelial cell isometric tension and myosin II regulatory light chain phosphorylation, [RefSeq, PubMed]; The polymorphism of bovine Cofilin-1 gene sequence variants and association analysis with growth traits in Qinchuan cattle., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 7, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q3SZ74", "ec_number_list": "", "go_molecular_function": "GO:0051015 actin filament binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0015629 actin cytoskeleton;GO:0030027 lamellipodium;GO:0030426 growth cone;GO:0016363 nuclear matrix", "go_biological_process": "GO:0051293 establishment of spindle localization;GO:0007015 actin filament organization;GO:0000281 mitotic cytokinesis;GO:0040019 positive regulation of embryonic development;GO:0051014 actin filament severing", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q5E9F7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q5E9F9-1", "uniprot_id": "PRS7_BOVIN", "mass": 48634.0, "length": 433, "protein_name": "26S proteasome regulatory subunit 7", "gene_name": "PSMC2", "organism": "Bovine", "refseq_name": "26S proteasome regulatory subunit 7", "refseq_ac": "NP_001015639", "gene_names_uniprotkb": "PSMC2", "gene_names_refseq": "PSMC2", "protein_names_uniprotkb": "26S proteasome regulatory subunit 7; 26S proteasome AAA-ATPase subunit RPT1; Proteasome 26S subunit ATPase 2", "protein_names_refseq": "26S protease regulatory subunit 7; 26S proteasome AAA-ATPase subunit RPT1; 26S proteasome regulatory subunit 7; proteasome (prosome, macropain) 26S subunit, ATPase, 2", "tax_id": 9913, "disease": "", "pathway": " (bta:530186); (R-BTA-1169091); (R-BTA-1234176); (R-BTA-1236978); (R-BTA-174084); (R-BTA-174154); (R-BTA-174178); (R-BTA-174184); (R-BTA-187577); (R-BTA-195253); (R-BTA-202424); (R-BTA-2467813); (R-BTA-2871837); (R-BTA-349425); (R-BTA-350562); (R-BTA-382556); (R-BTA-450408); (R-BTA-4608870); (R-BTA-4641257); (R-BTA-4641258); (R-BTA-5358346); (R-BTA-5607761); (R-BTA-5607764); (R-BTA-5610780); (R-BTA-5610785); (R-BTA-5632684); (R-BTA-5668541); (R-BTA-5676590); (R-BTA-5687128); (R-BTA-5689603); (R-BTA-5689880); (R-BTA-6798695); (R-BTA-68867); (R-BTA-68949); (R-BTA-69017); (R-BTA-69481); (R-BTA-69601); (R-BTA-75815); (R-BTA-8852276); (R-BTA-8854050); (R-BTA-8939236); (R-BTA-8939902); (R-BTA-8941858); (R-BTA-8948751); (R-BTA-8951664); (R-BTA-9020702); (R-BTA-9755511); (R-BTA-9762114); (R-BTA-9766229); (R-BTA-983168); (R-BTA-9907900); (R-BTA-9929356); (R-BTA-9929491); (R-BTA-9931269); (R-BTA-9932298); (R-BTA-9954709)", "pathway_count": 56, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC2 belongs to the heterohexameric ring of AAA (ATPases associated with diverse cellular activities) proteins that unfolds ubiquitinated target proteins that are concurrently translocated into a proteolytic chamber and degraded into peptides., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q3T0H8", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0036402 proteasome-activating activity", "go_cellular_component": "GO:0008540 proteasome regulatory particle, base subcomplex;GO:0022624 proteasome accessory complex;GO:0005634 nucleus;GO:0005829 cytosol;GO:0000932 P-body", "go_biological_process": "GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0006511 ubiquitin-dependent protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q5E9F9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q5E9H9-1", "uniprot_id": "ABHDA_BOVIN", "mass": 33983.0, "length": 306, "protein_name": "Palmitoyl-protein thioesterase ABHD10, mitochondrial", "gene_name": "ABHD10", "organism": "Bovine", "refseq_name": "palmitoyl-protein thioesterase ABHD10, mitochondrial precursor", "refseq_ac": "NP_001015606", "gene_names_uniprotkb": "ABHD10", "gene_names_refseq": "ABHD10", "protein_names_uniprotkb": "Palmitoyl-protein thioesterase ABHD10, mitochondrial; 3.1.1.93; 3.1.2.22; Abhydrolase domain-containing protein 10; Acyl-protein thioesterase ABHD10; Alpha/beta hydrolase domain-containing protein 10; Mycophenolic acid acyl-glucuronide esterase, mitochondrial", "protein_names_refseq": "abhydrolase domain-containing protein 10, mitochondrial; acyl-protein thioesterase ABHD10; alpha/beta hydrolase domain-containing protein 10, mitochondrial; mycophenolic acid acyl-glucuronide esterase, mitochondrial; palmitoyl-protein thioesterase ABHD10, mitochondrial precursor; palmitoyl-protein thioesterase ABHD10, mitochondrial", "tax_id": 9913, "disease": "", "pathway": " (bta:515563); (R-BTA-156588)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "Acts as an acyl-protein thioesterase that hydrolyzes fatty acids from acylated residues in proteins. Regulates the mitochondrial S-depalmitoylation of the nucleophilic active site residue of peroxiredoxin-5/PRDX5, a key antioxidant protein, therefore modulating mitochondrial antioxidant ability. Also catalyzes the deglucuronidation of mycophenolic acid acyl-glucuronide, an active metabolite of the immunosuppressant drug mycophenolate., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.1.2.22;3.1.2.2;3.1.1.93;3.4.19.12;2.3.1.-;3.1.2.-", "go_molecular_function": "GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds;GO:0102390 mycophenolic acid acyl-glucuronide esterase activity;GO:0008474 palmitoyl-(protein) hydrolase activity", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0002084 protein depalmitoylation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q5E9H9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q5E9N3-1", "uniprot_id": "RNF25_BOVIN", "mass": 51236.0, "length": 458, "protein_name": "E3 ubiquitin-protein ligase RNF25", "gene_name": "RNF25", "organism": "Bovine", "refseq_name": "E3 ubiquitin-protein ligase RNF25", "refseq_ac": "NP_001015575", "gene_names_uniprotkb": "RNF25", "gene_names_refseq": "RNF25", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase RNF25; 2.3.2.27; RING finger protein 25", "protein_names_refseq": "E3 ubiquitin-protein ligase RNF25; RING-type E3 ubiquitin transferase RNF25", "tax_id": 9913, "disease": "", "pathway": " (bta:511571)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "E3 ubiquitin-protein ligase that plays a key role in the RNF14-RNF25 translation quality control pathway, a pathway that takes place when a ribosome has stalled during translation, and which promotes ubiquitination and degradation of translation factors on stalled ribosomes. Catalyzes ubiquitination of RPS27A in response to ribosome collisions, promoting activation of RNF14. RNF25 catalyzes ubiquitination of other ribosomal proteins on stalled ribosomes, such as RPL0, RPL1, RPL12, RPS13 and RPS17. Also involved in ubiquitination and degradation of stalled ETF1/eRF1 (By similarity). Independently of its function in the response to stalled ribosomes, mediates ubiquitination and subsequent proteasomal degradation of NKD2 (By similarity). May also stimulate transcription mediated by NF-kappa-B via its interaction with RELA/p65 (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0051059 NF-kappaB binding;GO:0061630 ubiquitin protein ligase activity;GO:0004842 ubiquitin-protein transferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol", "go_biological_process": "GO:0072344 rescue of stalled ribosome;GO:0016567 protein ubiquitination;GO:0006511 ubiquitin-dependent protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q5E9N3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q5E9N9-1", "uniprot_id": "APEX2_BOVIN", "mass": 56938.0, "length": 514, "protein_name": "DNA-(apurinic or apyrimidinic site) endonuclease 2", "gene_name": "APEX2", "organism": "Bovine", "refseq_name": "DNA-(apurinic or apyrimidinic site) endonuclease 2", "refseq_ac": "NP_001015577", "gene_names_uniprotkb": "APEX2", "gene_names_refseq": "APEX2", "protein_names_uniprotkb": "DNA-(apurinic or apyrimidinic site) endonuclease 2; 3.1.11.2; AP endonuclease 2; APEX nuclease 2; Apurinic-apyrimidinic endonuclease 2", "protein_names_refseq": "AP endonuclease 2; APEX nuclease (apurinic/apyrimidinic endonuclease) 2; APEX nuclease 2; DNA-(apurinic or apyrimidinic site) endonuclease 2; DNA-(apurinic or apyrimidinic site) lyase 2; apurinic-apyrimidinic endonuclease 2", "tax_id": 9913, "disease": "", "pathway": " (bta:511790)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "Functions as a weak apurinic/apyrimidinic (AP) endodeoxyribonuclease in the DNA base excision repair (BER) pathway of DNA lesions induced by oxidative and alkylating agents (By similarity). Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends (By similarity). Also displays double-stranded DNA 3'-5' exonuclease, 3'-phosphodiesterase activities. Shows robust 3'-5' exonuclease activity on 3'-recessed heteroduplex DNA and is able to remove mismatched nucleotides preferentially (By similarity). Shows fairly strong 3'-phosphodiesterase activity involved in the removal of 3'-damaged termini formed in DNA by oxidative agents. In the nucleus functions in the PCNA-dependent BER pathway (By similarity). Plays a role in reversing blocked 3' DNA ends, problematic lesions that preclude DNA synthesis (By similarity). Required for somatic hypermutation (SHM) and DNA cleavage step of class switch recombination (CSR) of immunoglobulin genes (By similarity). Required for proper cell cycle progression during proliferation of peripheral lymphocytes (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q58D90", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity;GO:0008081 phosphoric diester hydrolase activity;GO:0008311 double-stranded DNA 3'-5' DNA exonuclease activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005739 mitochondrion", "go_biological_process": "GO:0006310 DNA recombination;GO:0006284 base-excision repair", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q5E9N9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q5E9P9-1", "uniprot_id": "GLYC_BOVIN", "mass": 52978.0, "length": 484, "protein_name": "Serine hydroxymethyltransferase, cytosolic", "gene_name": "SHMT1", "organism": "Bovine", "refseq_name": "serine hydroxymethyltransferase, cytosolic", "refseq_ac": "NP_001015553", "gene_names_uniprotkb": "SHMT1", "gene_names_refseq": "SHMT1", "protein_names_uniprotkb": "Serine hydroxymethyltransferase, cytosolic; 2.1.2.1; Glycine hydroxymethyltransferase; SHMT; Serine methylase", "protein_names_refseq": "SHMT; glycine hydroxymethyltransferase; serine hydroxymethyltransferase 1 (soluble); serine hydroxymethyltransferase, cytosolic; serine methylase", "tax_id": 9913, "disease": "", "pathway": " (bta:509002)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "Pyridoxal phosphate (PLP)-dependent enzyme that catalyzes the reversible conversion of serine and tetrahydrofolate (THF) to glycine and 5,10-methylene THF, serving as a critical component of the folate cycle and facilitating one-carbon biosynthetic reactions essential for methionine, purine, and pyrimidine synthesis (By similarity). While its central activity involves serine cleavage, the detailed catalytic mechanisms remain under study, including both retro-aldol cleavage of the PLP-serine C(alpha)-C(beta) bond followed by formaldehyde condensation with THF, and alternative nucleophilic displacement mechanisms of the C(alpha) atom of PLP-serine aldimine involving THF's N5 atom (By similarity). Also catalyzes the cleavage of various 3-hydroxy amino acids, such as L-allo-threonine, L-threonine and 3-phenylserine, forming glycine and the corresponding aldehyde through a retro-aldol process; additionally, it catalyzes the formation of 5-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate. Also functions as a hydroxytrimethyllysine aldolase (HTMLA) catalyzing the second step of the carnitine biosynthesis pathway and exhibits substrate preference with the erythro (S,S) configuration, and more efficiency with L-allo-threonine (By similarity). In the nucleus, first functions as a lamin-binding scaffold protein that is essential for assembling the de novo thymidylate synthesis complex by co-localizing DHFR and TYMS with the nuclear lamina and anchoring the complex to DNA replication sites. Subsequently, provides one-carbon substrates, specifically (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate, in situ for de novo dTMP synthesis to sustain DNA replication and repair during cell proliferation. Importantly, possesses RNA-binding capability, forming complexes that selectively regulate SHMT2 mRNA translation and dynamically modulate cytosolic and mitochondrial serine and glycine concentrations, thus influencing cellular metabolic status (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q2KIP4", "ec_number_list": "2.1.2.1", "go_molecular_function": "GO:0030170 pyridoxal phosphate binding;GO:0005521 lamin binding;GO:0004372 glycine hydroxymethyltransferase activity;GO:0008732 L-allo-threonine aldolase activity;GO:0050179 phenylserine aldolase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005829 cytosol", "go_biological_process": "GO:0006231 dTMP biosynthetic process;GO:0051289 protein homotetramerization;GO:0035999 tetrahydrofolate interconversion;GO:0046653 tetrahydrofolate metabolic process;GO:0006544 glycine metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q5E9P9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q5E9T7-1", "uniprot_id": "JADE1_BOVIN", "mass": 58312.0, "length": 509, "protein_name": "Protein Jade-1", "gene_name": "JADE1", "organism": "Bovine", "refseq_name": "protein Jade-1", "refseq_ac": "NP_001015559", "gene_names_uniprotkb": "JADE1; PHF17", "gene_names_refseq": "JADE1; PHF17", "protein_names_uniprotkb": "Protein Jade-1; Jade family PHD finger protein 1; PHD finger protein 17", "protein_names_refseq": "PHD finger protein 17; PHD protein Jade-1; jade family PHD finger protein 1; protein Jade-1", "tax_id": 9913, "disease": "", "pathway": " (bta:509264)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "Scaffold subunit of some HBO1 complexes, which have a histone H4 acetyltransferase activity. Plays a key role in HBO1 complex by directing KAT7/HBO1 specificity towards histone H4 acetylation (H4K5ac, H4K8ac and H4K12ac), regulating DNA replication initiation, regulating DNA replication initiation. May also promote acetylation of nucleosomal histone H4 by KAT5. Promotes apoptosis. May act as a renal tumor suppressor. Negatively regulates canonical Wnt signaling; at least in part, cooperates with NPHP4 in this function., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0140566 histone reader activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0000123 histone acetyltransferase complex", "go_biological_process": "GO:0006338 chromatin remodeling;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0006915 apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q5E9T7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q5E9Z1-1", "uniprot_id": "RUSD4_BOVIN", "mass": 42000.0, "length": 377, "protein_name": "Pseudouridylate synthase RPUSD4, mitochondrial", "gene_name": "RPUSD4", "organism": "Bovine", "refseq_name": "pseudouridylate synthase RPUSD4, mitochondrial", "refseq_ac": "NP_001015616", "gene_names_uniprotkb": "RPUSD4", "gene_names_refseq": "RPUSD4", "protein_names_uniprotkb": "Pseudouridylate synthase RPUSD4, mitochondrial; 5.4.99.-; RNA pseudouridylate synthase domain-containing protein 4", "protein_names_refseq": "RNA pseudouridylate synthase domain containing 4; RNA pseudouridylate synthase domain-containing protein 4; mitochondrial RNA pseudouridine synthase RPUSD4; pseudouridylate synthase RPUSD4, mitochondrial", "tax_id": 9913, "disease": "", "pathway": " (bta:516934)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "Catalyzes uridine to pseudouridine isomerization (pseudouridylation) of different mitochondrial RNA substrates. Acts on position 1397 in 16S mitochondrial ribosomal RNA (16S mt-rRNA). This modification is required for the assembly of 16S mt-rRNA into a functional mitochondrial ribosome. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mt-rRNA, controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation. Acts on position 39 in mitochondrial tRNA(Phe). Also catalyzes pseudouridylation of mRNAs in nucleus: acts as a regulator of pre-mRNA splicing by mediating pseudouridylation of pre-mRNAs at locations associated with alternatively spliced regions. Pseudouridylation of pre-mRNAs near splice sites directly regulates mRNA splicing and mRNA 3'-end processing., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A7YWI2;Q0V8H4;Q1JP71;Q1JPL3;Q58D36;Q58DF5;Q5E9Z6", "ec_number_list": "5.4.99.25;5.4.99.12;5.4.99.-", "go_molecular_function": "GO:0003723 RNA binding;GO:0009982 pseudouridine synthase activity;GO:0106029 tRNA pseudouridine synthase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0000455 enzyme-directed rRNA pseudouridine synthesis;GO:0006397 mRNA processing;GO:0008033 tRNA processing;GO:0008380 RNA splicing;GO:0070131 positive regulation of mitochondrial translation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q5E9Z1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q5E9Z9-1", "uniprot_id": "NECT4_BOVIN", "mass": 55416.0, "length": 510, "protein_name": "Nectin-4", "gene_name": "NECTIN4", "organism": "Bovine", "refseq_name": "nectin-4 precursor", "refseq_ac": "NP_001019665", "gene_names_uniprotkb": "NECTIN4; PVRL4", "gene_names_refseq": "NECTIN4; PVRL4", "protein_names_uniprotkb": "Nectin-4; Nectin cell adhesion molecule 4; Poliovirus receptor-related protein 4", "protein_names_refseq": "nectin-4 precursor; nectin-4; poliovirus receptor-related protein 4", "tax_id": 9913, "disease": "", "pathway": " (bta:507718)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "Seems to be involved in cell adhesion through trans-homophilic and -heterophilic interactions, the latter including specifically interactions with NECTIN1. Plays a role in the senescence-associated cell size enlargement via SFK/PI3K/Rac1 and thus promotes senescent cell survival. Also participates in the innate immune response by acting as a ligand for the receptor TIGIT to inhibit NK-cell activity., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0098631 cell adhesion mediator activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005912 adherens junction", "go_biological_process": "GO:0046718 symbiont entry into host cell;GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules;GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q5E9Z9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q5EA15-1", "uniprot_id": "BHE40_BOVIN", "mass": 45621.0, "length": 412, "protein_name": "Class E basic helix-loop-helix protein 40", "gene_name": "BHLHE40", "organism": "Bovine", "refseq_name": "class E basic helix-loop-helix protein 40", "refseq_ac": "NP_001020100", "gene_names_uniprotkb": "BHLHE40; BHLHB2", "gene_names_refseq": "BHLHB2; BHLHE40; DEC1", "protein_names_uniprotkb": "Class E basic helix-loop-helix protein 40; Class B basic helix-loop-helix protein 2; bHLHb2; bHLHe40", "protein_names_refseq": "basic helix-loop-helix domain containing, class B, 2; class B basic helix-loop-helix protein 2; class E basic helix-loop-helix protein 40; differentiated embryo chondrocyte expressed gene 1", "tax_id": 9913, "disease": "", "pathway": " (bta:506945)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "16305752;25509349;29350420", "class_list": "", "function": "Overexpression of DEC1 blocked myogenesis by inhibiting MyoG promoter activity in bovine., [RefSeq, PubMed]; This gene encodes a basic helix-loop-helix protein expressed in various tissues. The encoded protein can interact with ARNTL or compete for E-box binding sites in the promoter of PER1 and repress CLOCK/ARNTL's transactivation of PER1. This gene is believed to be involved in the control of circadian rhythm and cell differentiation. [provided by RefSeq, Feb 2014]., [RefSeq]; This study aimed to lay the groundwork to further study of Bhlhe40 function at myogenesis and adipogenesis in bovine and should significantly contribute to cattle breeding and genetics through MAS program, [RefSeq, PubMed]; Transcriptional repressor involved in the regulation of the circadian rhythm by negatively regulating the activity of the clock genes and clock-controlled genes. Acts as the negative limb of a novel autoregulatory feedback loop (DEC loop) which differs from the one formed by the PER and CRY transcriptional repressors (PER/CRY loop). Both these loops are interlocked as it represses the expression of PER1/2 and in turn is repressed by PER1/2 and CRY1/2. Represses the activity of the circadian transcriptional activator: CLOCK-BMAL1|BMAL2 heterodimer by competing for the binding to E-box elements (5'-CACGTG-3') found within the promoters of its target genes. Negatively regulates its own expression and the expression of DBP and BHLHE41/DEC2. Acts as a corepressor of RXR and the RXR-LXR heterodimers and represses the ligand-induced RXRA and NR1H3/LXRA transactivation activity. May be involved in the regulation of chondrocyte differentiation via the cAMP pathway (By similarity). Represses the transcription of NR0B2 and attenuates the transactivation of NR0B2 by the CLOCK-BMAL1 complex (By similarity). Drives the circadian rhythm of blood pressure through transcriptional repression of ATP1B1 in the cardiovascular system (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0019904 protein domain specific binding;GO:0042803 protein homodimerization activity;GO:0046982 protein heterodimerization activity;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0016604 nuclear body", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0045892 negative regulation of DNA-templated transcription;GO:0007623 circadian rhythm;GO:0009952 anterior/posterior pattern specification", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q5EA15-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q5EA41-1", "uniprot_id": "GALT6_BOVIN", "mass": 71138.0, "length": 622, "protein_name": "Polypeptide N-acetylgalactosaminyltransferase 6", "gene_name": "GALNT6", "organism": "Bovine", "refseq_name": "polypeptide N-acetylgalactosaminyltransferase 6", "refseq_ac": "NP_001015534", "gene_names_uniprotkb": "GALNT6", "gene_names_refseq": "GALNT6", "protein_names_uniprotkb": "Polypeptide N-acetylgalactosaminyltransferase 6; 2.4.1.41; GalNAc-T6; Polypeptide GalNAc transferase 6; Protein-UDP acetylgalactosaminyltransferase 6; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 6; pp-GaNTase 6", "protein_names_refseq": "UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 6; UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6 (GalNAc-T6); galNAc-T6; polypeptide GalNAc transferase 6; polypeptide N-acetylgalactosaminyltransferase 6; pp-GaNTase 6; protein-UDP acetylgalactosaminyltransferase 6", "tax_id": 9913, "disease": "", "pathway": " (bta:506903)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. May participate in synthesis of oncofetal fibronectin. Has activity toward MUC1A, MUC2, EA2 and fibronectin peptides (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.4.1.-;2.4.1.41", "go_molecular_function": "GO:0046872 metal ion binding;GO:0030246 carbohydrate binding;GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005794 Golgi apparatus", "go_biological_process": "GO:0006493 protein O-linked glycosylation;GO:0016266 protein O-linked glycosylation via N-acetyl-galactosamine", "synthesized_glycan_count": 7434, "hit_score": 0.2, "record_id": "Q5EA41-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q5EA61-1", "uniprot_id": "KCRB_BOVIN", "mass": 42719.0, "length": 381, "protein_name": "Creatine kinase B-type", "gene_name": "CKB", "organism": "Bovine", "refseq_name": "creatine kinase B-type", "refseq_ac": "NP_001015613", "gene_names_uniprotkb": "CKB", "gene_names_refseq": "B-CK; CKB; CPK-B", "protein_names_uniprotkb": "Creatine kinase B-type; 2.7.3.2; B-CK; CPK-B; Creatine kinase B chain; Creatine phosphokinase M-type", "protein_names_refseq": "creatine kinase B chain; creatine kinase B-type; creatine kinase, brain; creatine phosphokinase M-type", "tax_id": 9913, "disease": "", "pathway": " (bta:516210); (R-BTA-71288); (R-BTA-9696264)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa. Acts as a key regulator of adaptive thermogenesis as part of the futile creatine cycle: localizes to the mitochondria of thermogenic fat cells and acts by mediating phosphorylation of creatine to initiate a futile cycle of creatine phosphorylation and dephosphorylation. During the futile creatine cycle, creatine and N-phosphocreatine are in a futile cycle, which dissipates the high energy charge of N-phosphocreatine as heat without performing any mechanical or chemical work., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.3.2;2.7.10.1;3.1.3.48;3.4.17.22;3.6.4.13", "go_molecular_function": "GO:0004111 creatine kinase activity;GO:0005524 ATP binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005739 mitochondrion;GO:0005829 cytosol;GO:0005886 plasma membrane", "go_biological_process": "GO:0046314 phosphocreatine biosynthetic process;GO:0030644 intracellular chloride ion homeostasis;GO:0007420 brain development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q5EA61-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q5EA79-1", "uniprot_id": "GALM_BOVIN", "mass": 37614.0, "length": 342, "protein_name": "Galactose mutarotase", "gene_name": "GALM", "organism": "Bovine", "refseq_name": "galactose mutarotase", "refseq_ac": "NP_001029967", "gene_names_uniprotkb": "GALM", "gene_names_refseq": "GALM", "protein_names_uniprotkb": "Galactose mutarotase; 5.1.3.3; Aldose 1-epimerase", "protein_names_refseq": "aldose 1-epimerase; galactose mutarotase", "tax_id": 9913, "disease": "", "pathway": " (bta:616676); (R-BTA-70370)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "Mutarotase that catalyzes the interconversion of beta-D-galactose and alpha-D-galactose during galactose metabolism. Beta-D-galactose is metabolized in the liver into glucose 1-phosphate, the primary metabolic fuel, by the action of four enzymes that constitute the Leloir pathway: GALM, GALK1 (galactokinase), GALT (galactose-1-phosphate uridylyltransferase) and GALE (UDP-galactose-4'-epimerase). Involved in the maintenance of the equilibrium between the beta- and alpha-anomers of galactose, therefore ensuring a sufficient supply of the alpha-anomer for GALK1. Also active on D-glucose although shows a preference for galactose over glucose., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q3T0D4", "ec_number_list": "5.1.3.3", "go_molecular_function": "GO:0030246 carbohydrate binding;GO:0004034 aldose 1-epimerase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0006006 glucose metabolic process;GO:0033499 galactose catabolic process via UDP-galactose, Leloir pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q5EA79-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q5EA85-1", "uniprot_id": "SEM4A_BOVIN", "mass": 83627.0, "length": 762, "protein_name": "Semaphorin-4A", "gene_name": "SEMA4A", "organism": "Bovine", "refseq_name": "semaphorin-4A precursor", "refseq_ac": "NP_001068908", "gene_names_uniprotkb": "SEMA4A", "gene_names_refseq": "SEMA4A", "protein_names_uniprotkb": "Semaphorin-4A", "protein_names_refseq": "sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A; semaphorin B; semaphorin-4A precursor", "tax_id": 9913, "disease": "", "pathway": " (bta:510239)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "Cell surface receptor for PLXNB1, PLXNB2, PLXNB3 and PLXND1 that plays an important role in cell-cell signaling (By similarity). Regulates glutamatergic and GABAergic synapse development (By similarity). Promotes the development of inhibitory synapses in a PLXNB1-dependent manner and promotes the development of excitatory synapses in a PLXNB2-dependent manner (By similarity). Plays a role in priming antigen-specific T-cells, promotes differentiation of Th1 T-helper cells, and thereby contributes to adaptive immunity (By similarity). Promotes phosphorylation of TIMD2 (By similarity). Inhibits angiogenesis (By similarity). Promotes axon growth cone collapse (By similarity). Inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 6, "predicted_n_glycosites": 5, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 6, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0030215 semaphorin receptor binding;GO:0038191 neuropilin binding;GO:0045499 chemorepellent activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0001525 angiogenesis;GO:0030335 positive regulation of cell migration;GO:0071526 semaphorin-plexin signaling pathway;GO:0001755 neural crest cell migration;GO:0002250 adaptive immune response", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q5EA85-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q5EAB6-1", "uniprot_id": "PMGT1_BOVIN", "mass": 75077.0, "length": 660, "protein_name": "Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1", "gene_name": "POMGNT1", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "POMGNT1", "gene_names_refseq": "", "protein_names_uniprotkb": "Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1; 2.4.1.-; POMGnT1", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "Participates in O-mannosyl glycosylation by catalyzing the addition of N-acetylglucosamine to O-linked mannose on glycoproteins. Catalyzes the synthesis of the GlcNAc(beta1-2)Man(alpha1-)O-Ser/Thr moiety on alpha-dystroglycan and other O-mannosylated proteins, providing the necessary basis for the addition of further carbohydrate moieties. Is specific for alpha linked terminal mannose., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.4.1.-;2.4.1.101", "go_molecular_function": "GO:0030145 manganese ion binding;GO:0008375 acetylglucosaminyltransferase activity;GO:0030246 carbohydrate binding;GO:0047223 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0016020 membrane", "go_biological_process": "GO:0006493 protein O-linked glycosylation;GO:0016266 protein O-linked glycosylation via N-acetyl-galactosamine", "synthesized_glycan_count": 198, "hit_score": 0.2, "record_id": "Q5EAB6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q5EAC7-1", "uniprot_id": "CPIN1_BOVIN", "mass": 33205.0, "length": 310, "protein_name": "Anamorsin", "gene_name": "CIAPIN1", "organism": "Bovine", "refseq_name": "anamorsin", "refseq_ac": "NP_001015659", "gene_names_uniprotkb": "CIAPIN1", "gene_names_refseq": "CIAPIN1", "protein_names_uniprotkb": "Anamorsin; Cytokine-induced apoptosis inhibitor 1; Fe-S cluster assembly protein DRE2 homolog", "protein_names_refseq": "anamorsin; fe-S cluster assembly protein DRE2 homolog", "tax_id": 9913, "disease": "", "pathway": " (bta:535119)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex NUBP1-NUBP2. Electrons are transferred to CIAPIN1 from NADPH via the FAD- and FMN-containing protein NDOR1. NDOR1-CIAPIN1 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit. Has anti-apoptotic effects in the cell. Involved in negative control of cell death upon cytokine withdrawal. Promotes development of hematopoietic cells., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 7, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q0VCL8", "ec_number_list": "", "go_molecular_function": "GO:0009055 electron transfer activity;GO:0046872 metal ion binding;GO:0051539 4 iron, 4 sulfur cluster binding;GO:0051537 2 iron, 2 sulfur cluster binding", "go_cellular_component": "GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0005758 mitochondrial intermembrane space", "go_biological_process": "GO:0016226 iron-sulfur cluster assembly;GO:0043066 negative regulation of apoptotic process;GO:0006915 apoptotic process;GO:0030097 hemopoiesis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q5EAC7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q5EAD2-1", "uniprot_id": "SERA_BOVIN", "mass": 56452.0, "length": 533, "protein_name": "D-3-phosphoglycerate dehydrogenase", "gene_name": "PHGDH", "organism": "Bovine", "refseq_name": "D-3-phosphoglycerate dehydrogenase", "refseq_ac": "NP_001030189", "gene_names_uniprotkb": "PHGDH", "gene_names_refseq": "PHGDH", "protein_names_uniprotkb": "D-3-phosphoglycerate dehydrogenase; 1.1.1.37; 1.1.1.399; 1.1.1.95; 2-oxoglutarate reductase; 3-PGDH; Malate dehydrogenase", "protein_names_refseq": "2-oxoglutarate reductase; 3-PGDH; D-3-phosphoglycerate dehydrogenase; malate dehydrogenase", "tax_id": 9913, "disease": "", "pathway": " (bta:505103)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate and the reversible oxidation of (S)-malate to oxaloacetate., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q2KJ79", "ec_number_list": "1.1.1.95;1.1.1.37;1.1.1.399", "go_molecular_function": "GO:0051287 NAD binding;GO:0004617 phosphoglycerate dehydrogenase activity;GO:0030060 L-malate dehydrogenase (NAD+) activity", "go_cellular_component": "", "go_biological_process": "GO:0006564 L-serine biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q5EAD2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q5I2E5-1", "uniprot_id": "FCN2_BOVIN", "mass": 35339.0, "length": 329, "protein_name": "Ficolin-2", "gene_name": "FCN2", "organism": "Bovine", "refseq_name": "ficolin-2 precursor", "refseq_ac": "NP_001010996", "gene_names_uniprotkb": "FCN2", "gene_names_refseq": "FCN1; FCN2; FCNB", "protein_names_uniprotkb": "Ficolin-2; Collagen/fibrinogen domain-containing protein 2; Ficolin-B; Ficolin-beta; L-ficolin", "protein_names_refseq": "L-ficolin; collagen/fibrinogen domain-containing protein 2; ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin); ficolin (collagen/fibrinogen domain containing) 1; ficolin B; ficolin-2 precursor; ficolin-2; ficolin-beta", "tax_id": 9913, "disease": "", "pathway": " (bta:497016); (R-BTA-2855086); (R-BTA-6798695)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Calcium-dependent lectin, which acts as a pattern recognition receptor that initiates the lectin pathway of the complement system, a cascade of proteins that leads to phagocytosis and breakdown of pathogens and signaling that strengthens the adaptive immune system. Specifically recognizes and binds carbohydrates on the pathogen surface, activating the MASP1 serine protease and initiating the proteolytic cascade of the lectin complement pathway. Specifically binds N-Acetylglucosamine (GlcNAc), as well as phosphocholine and lipoteichoic acid moieties on the surface of pathogens., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005102 signaling receptor binding;GO:0046872 metal ion binding;GO:0030246 carbohydrate binding;GO:0070892 lipoteichoic acid immune receptor activity;GO:0003823 antigen binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0009986 cell surface;GO:0031012 extracellular matrix;GO:0106139 symbiont cell surface", "go_biological_process": "GO:0001867 complement activation, lectin pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q5I2E5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q5I3B1-1", "uniprot_id": "IOD3_BOVIN", "mass": 33888.0, "length": 301, "protein_name": "Thyroxine 5-deiodinase", "gene_name": "DIO3", "organism": "Bovine", "refseq_name": "thyroxine 5-deiodinase", "refseq_ac": "NP_001010993", "gene_names_uniprotkb": "DIO3", "gene_names_refseq": "DIO3", "protein_names_uniprotkb": "Thyroxine 5-deiodinase; 1.21.99.3; 5DIII; DIOIII; Type 3 DI; Type III iodothyronine deiodinase", "protein_names_refseq": "5DIII; DIOIII; deiodinase, iodothyronine type III; thyroxine 5-deiodinase; type 3 DI; type III iodothyronine deiodinase; type-III 5'-deiodinase", "tax_id": 9913, "disease": "", "pathway": " (bta:494549); (R-BTA-350864)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "15932406;19393038;28674234", "class_list": "", "function": "An allele-specific expression analysis-based SNP method revealed that DIO3 and DIO3OS genes exhibited monoallelic expression in the eight tissues, indicating that DIO3 and DIO3OS are imprinted in cattle., [RefSeq, PubMed]; Plays a crucial role in the metabolism of thyroid hormones (TH) and has specific roles in TH activation and inactivation by deiodination (By similarity). Catalyzes the deiodination of L-thyroxine (T4) to 3,3',5'-triiodothyronine (rT3), 3,5,3'-triiodothyronine (T3) to 3,3'-diiodothyronine (3,3'-T2), 3,5-diiodothyronine (3,5-T2) to 3-monoiodothyronine (3-T1), rT3 to 3',5'-diiodothyronine (3',5'-T2) and 3,3'-T2 to 3'-monoiodothyronine (3'-T1) via inner-ring deiodination (IRD) (By similarity). Catalyzes the deiodination of 3-T1 to L-thyronine (T0) via outer-ring deiodination (ORD) (By similarity). Catalyzes the tyrosyl ring deiodinations of 3,3',5,5'-tetraiodothyronamine, 3,3',5'-triiodothyronamine, 3,5,3'-triiodothyronamine, 3,5-diiodothyronamine, 3,3'-diiodothyronamine and 3-iodothyronamine (By similarity)., [UniProtKB, UniProtKB]; The protein encoded by this intronless gene belongs to the iodothyronine deiodinase family. It catalyzes the inactivation of thyroid hormone by inner ring deiodination of the prohormone thyroxine (T4) and the bioactive hormone 3,3',5-triiodothyronine (T3) to inactive metabolites, 3,3',5'-triiodothyronine (RT3) and 3,3'-diiodothyronine (T2), respectively. It is highly expressed in placenta, fetal and neonatal tissues, and thought to prevent premature exposure of developing fetal tissues to adult levels of thyroid hormones. It thus plays a critical role in mammalian development by regulating circulating fetal thyroid hormone concentration. This protein is a selenoprotein, containing the rare selenocysteine (Sec) amino acid at its active site. Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. [provided by RefSeq, Jun 2016]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.21.99.3", "go_molecular_function": "GO:0033798 thyroxine 5-deiodinase activity;GO:0004800 thyroxine 5'-deiodinase activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0010008 endosome membrane", "go_biological_process": "GO:0042404 thyroid hormone catabolic process;GO:0042446 hormone biosynthetic process;GO:0042403 thyroid hormone metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q5I3B1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q5I3B2-1", "uniprot_id": "IOD2_BOVIN", "mass": 30303.0, "length": 269, "protein_name": "Type II iodothyronine deiodinase", "gene_name": "DIO2", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "DIO2", "gene_names_refseq": "", "protein_names_uniprotkb": "Type II iodothyronine deiodinase; 1.21.99.4; 5DII; DIOII; Type 2 DI; Type-II 5'-deiodinase", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (bta:494548); (R-BTA-350864)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "15932406", "class_list": "", "function": "Plays a crucial role in the metabolism of thyroid hormones (TH) and has specific roles in TH activation and inactivation by deiodination (By similarity). Catalyzes the deiodination of L-thyroxine (T4) to 3,5,3'-triiodothyronine (T3), 3,3',5'-triiodothyronine (rT3) to 3,3'-diiodothyronine (3,3'-T2) and 3',5'-diiodothyronine (3',5'-T2) to 3'-monoiodothyronine (3'-T1) via outer-ring deiodination (ORD) (By similarity). Catalyzes the phenolic ring deiodinations of 3,3',5'-triiodothyronamine and 3',5'- diiodothyronamine (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.21.99.4", "go_molecular_function": "GO:0033798 thyroxine 5-deiodinase activity;GO:0031625 ubiquitin protein ligase binding;GO:0004800 thyroxine 5'-deiodinase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0042404 thyroid hormone catabolic process;GO:0042446 hormone biosynthetic process;GO:0042403 thyroid hormone metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q5I3B2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q5J316-1", "uniprot_id": "GTR12_BOVIN", "mass": 67468.0, "length": 621, "protein_name": "Solute carrier family 2, facilitated glucose transporter member 12", "gene_name": "SLC2A12", "organism": "Bovine", "refseq_name": "solute carrier family 2, facilitated glucose transporter member 12", "refseq_ac": "NP_001011683", "gene_names_uniprotkb": "SLC2A12; GLUT12", "gene_names_refseq": "GLUT12; SLC2A12", "protein_names_uniprotkb": "Solute carrier family 2, facilitated glucose transporter member 12; GLUT-12; Glucose transporter type 12", "protein_names_refseq": "GLUT-12; glucose transporter type 12; solute carrier family 2 (facilitated glucose transporter), member 12; solute carrier family 2, facilitated glucose transporter member 12", "tax_id": 9913, "disease": "", "pathway": " (bta:497031)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "16284803", "class_list": "", "function": "Insulin-independent facilitative glucose transporter., [UniProtKB, UniProtKB]", "predicted_glycosites": 5, "predicted_n_glycosites": 5, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0055056 D-glucose transmembrane transporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane;GO:0048471 perinuclear region of cytoplasm;GO:0012505 endomembrane system", "go_biological_process": "GO:0072359 circulatory system development;GO:1904659 D-glucose transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q5J316-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q5NTB3-1", "uniprot_id": "FA11_BOVIN", "mass": 69872.0, "length": 625, "protein_name": "Coagulation factor XI", "gene_name": "F11", "organism": "Bovine", "refseq_name": "coagulation factor XI precursor", "refseq_ac": "NP_001008665", "gene_names_uniprotkb": "F11", "gene_names_refseq": "F11; FXI", "protein_names_uniprotkb": "Coagulation factor XI; 3.4.21.27; FXI; PTA; Plasma thromboplastin antecedent", "protein_names_refseq": "PTA; blood coagulation factor XI; coagulation factor XI precursor; plasma thromboplastin antecedent", "tax_id": 9913, "disease": "", "pathway": " (bta:407998)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "15785014;16104386;19433912;21087874;36724509", "class_list": "", "function": "DNA was extracted and amplified from the bovine mummified fetuses, and the samples were successfully tested for Factor XI gene deficiency in the mummies., [RefSeq, PubMed]; Factor XI triggers the middle phase of the intrinsic pathway of blood coagulation by activating factor IX., [UniProtKB, UniProtKB]; Insertion of 15 nucleotides in the F11 gene is the causative mutation for factor XI deficiency in Japanese black cattle., [RefSeq, PubMed]; Sequence analysis of the bovine coagulation factor XI (F11) gene revealed an unusually high number of non-synonymous mutations. However, none of the mutations in the F11 gene were concordant with Bovine neonatal pancytopenia status., [RefSeq, PubMed]; The molecular basis of coagulopathy has been recognized in Holstein cattle as a 76-bp insertion in the coding region of the FXI gene, [RefSeq, PubMed]; Thrombogenic potential of picomolar coagulation factor XIa is mediated by thrombin wave propagation., [RefSeq, PubMed]", "predicted_glycosites": 4, "predicted_n_glycosites": 4, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004252 serine-type endopeptidase activity;GO:0008201 heparin binding;GO:0008236 serine-type peptidase activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0007596 blood coagulation;GO:0031639 plasminogen activation;GO:0051919 positive regulation of fibrinolysis", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q5NTB3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q5QQ49-1", "uniprot_id": "XYLT2_BOVIN", "mass": 97189.0, "length": 867, "protein_name": "Xylosyltransferase 2", "gene_name": "XYLT2", "organism": "Bovine", "refseq_name": "xylosyltransferase 2", "refseq_ac": "NP_001008667", "gene_names_uniprotkb": "XYLT2", "gene_names_refseq": "XYLT2", "protein_names_uniprotkb": "Xylosyltransferase 2; 2.4.2.26; Peptide O-xylosyltransferase 2; Xylosyltransferase II", "protein_names_refseq": "peptide O-xylosyltransferase 2; xylosyltransferase 2; xylosyltransferase II", "tax_id": 9913, "disease": "", "pathway": " (bta:493989)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalyzes the first step in the biosynthesis of chondroitin sulfate, heparan sulfate and dermatan sulfate proteoglycans, such as DCN (By similarity). Transfers D-xylose from UDP-D-xylose to specific serine residues of the core protein (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 6, "predicted_n_glycosites": 3, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 6, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.4.2.26", "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0030145 manganese ion binding;GO:0030158 protein xylosyltransferase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005615 extracellular space", "go_biological_process": "GO:0015012 heparan sulfate proteoglycan biosynthetic process;GO:0050650 chondroitin sulfate proteoglycan biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q5QQ49-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q5XQN5-1", "uniprot_id": "K2C5_BOVIN", "mass": 62937.0, "length": 601, "protein_name": "Keratin, type II cytoskeletal 5", "gene_name": "KRT5", "organism": "Bovine", "refseq_name": "keratin, type II cytoskeletal 5", "refseq_ac": "NP_001008663", "gene_names_uniprotkb": "KRT5", "gene_names_refseq": "KRT5", "protein_names_uniprotkb": "Keratin, type II cytoskeletal 5; CK-5; Cytokeratin-5; K5; Keratin-5; Type-II keratin Kb5", "protein_names_refseq": "CK-5; K5; cytokeratin-5; keratin 5 (epidermolysis bullosa simplex, Dowling-Meara/Kobner/Weber-Cockayne types); keratin, type II cytoskeletal 5; keratin, type II cytoskeletal 60 kDa, component III; type-II keratin Kb5", "tax_id": 9913, "disease": "", "pathway": " (bta:281268)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "15955091;23911870;41018975", "class_list": "", "function": "G to A substitution in all affected animals. This mutation leads to an amino acid change of glutamic acid to lysine in the final E (478) of the KLLEGE motif of the protein., [RefSeq, PubMed]; NMHC IIA may play critical roles in the early trophoblast-derived ectoplacental cone and extraembryonic ectoderm in Keratin 5-Cre transgenic mice., [RefSeq, PubMed]; Structural component of intermediate filaments in basal keratinocytes of stratified epithelia. Together with its obligate type I partner KRT14, contributes to the formation of the keratin intermediate filament network that provides mechanical stability and resilience to the basal layer of the epidermis (By similarity). Regulates the recruitment of Langerhans cells to the epidermis, potentially by modulation of the abundance of macrophage chemotactic cytokines, macrophage inflammatory cytokines and CTNND1 localization in keratinocytes (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 13, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0030280 structural constituent of skin epidermis", "go_cellular_component": "GO:0005737 cytoplasm;GO:0045095 keratin filament", "go_biological_process": "GO:0030855 epithelial cell differentiation;GO:0031424 keratinization;GO:0050680 negative regulation of epithelial cell proliferation;GO:0009612 response to mechanical stimulus;GO:0032880 regulation of protein localization", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q5XQN5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q645M6-1", "uniprot_id": "FADD_BOVIN", "mass": 23002.0, "length": 209, "protein_name": "FAS-associated death domain protein", "gene_name": "FADD", "organism": "Bovine", "refseq_name": "FAS-associated death domain protein", "refseq_ac": "NP_001007817", "gene_names_uniprotkb": "FADD", "gene_names_refseq": "FADD", "protein_names_uniprotkb": "FAS-associated death domain protein; FAS-associating death domain-containing protein", "protein_names_refseq": "FAS-associated death domain protein; FAS-associating death domain-containing protein; Fas (TNFRSF6)-associated via death domain; protein FADD", "tax_id": 9913, "disease": "", "pathway": " (bta:493720); (R-BTA-140534); (R-BTA-2562578); (R-BTA-3371378); (R-BTA-5218900); (R-BTA-5357786); (R-BTA-5357905); (R-BTA-5675482); (R-BTA-69416); (R-BTA-75157)", "pathway_count": 10, "publication_count": 1, "publication_id_list": "15670133", "class_list": "", "function": "Apoptotic adapter molecule that recruits caspases CASP8 or CASP10 to the activated FAS/CD95 or TNFRSF1A/TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs CASP8 proteolytic activation. Active CASP8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling., [UniProtKB, UniProtKB]; Mapping and sequencing of bovine FADD cDNA, and characterization of its expression in endothelial cells, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0042802 identical protein binding;GO:0035591 signaling adaptor activity;GO:0035877 death effector domain binding;GO:0089720 caspase binding;GO:0005123 death receptor binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0031265 CD95 death-inducing signaling complex;GO:0097342 ripoptosome", "go_biological_process": "GO:0045087 innate immune response;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0051607 defense response to virus;GO:0006915 apoptotic process;GO:0043123 positive regulation of canonical NF-kappaB signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q645M6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q67ER4-1", "uniprot_id": "R113A_BOVIN", "mass": 38849.0, "length": 343, "protein_name": "E3 ubiquitin-protein ligase RNF113A", "gene_name": "RNF113A", "organism": "Bovine", "refseq_name": "E3 ubiquitin-protein ligase RNF113A", "refseq_ac": "NP_001007808", "gene_names_uniprotkb": "RNF113A; ZNF183", "gene_names_refseq": "RNF113A; ZNF183", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase RNF113A; 2.3.2.27; RING finger protein 113A; Zinc finger protein 183", "protein_names_refseq": "E3 ubiquitin-protein ligase RNF113A; zinc finger protein 183", "tax_id": 9913, "disease": "", "pathway": " (bta:493640)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Required for pre-mRNA splicing as component of the spliceosome. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (By similarity). E3 ubiquitin-protein ligase that catalyzes the transfer of ubiquitin onto target proteins. Catalyzes polyubiquitination of SNRNP200/BRR2 with non-canonical 'Lys-63'-linked polyubiquitin chains. Plays a role in DNA repair via its role in the synthesis of 'Lys-63'-linked polyubiquitin chains that recruit ALKBH3 and the ASCC complex to sites of DNA damage by alkylating agents. Ubiquitinates CXCR4, leading to its degradation, and thereby contributes to the termination of CXCR4 signaling., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q2HJ85", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity;GO:0004842 ubiquitin-protein transferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0016607 nuclear speck;GO:0005684 U2-type spliceosomal complex;GO:0071005 U2-type precatalytic spliceosome", "go_biological_process": "GO:0070100 negative regulation of chemokine-mediated signaling pathway;GO:0006281 DNA repair;GO:0016567 protein ubiquitination;GO:0000398 mRNA splicing, via spliceosome", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q67ER4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q68RJ9-1", "uniprot_id": "CART_BOVIN", "mass": 12790.0, "length": 116, "protein_name": "Cocaine- and amphetamine-regulated transcript protein", "gene_name": "CARTPT", "organism": "Bovine", "refseq_name": "cocaine- and amphetamine-regulated transcript protein precursor", "refseq_ac": "NP_001007821", "gene_names_uniprotkb": "CARTPT; CART", "gene_names_refseq": "CARTPT; CART", "protein_names_uniprotkb": "Cocaine- and amphetamine-regulated transcript protein", "protein_names_refseq": "cocaine and amphetamine responsive transcript; cocaine- and amphetamine-regulated transcript protein precursor; cocaine- and amphetamine-regulated transcript protein", "tax_id": 9913, "disease": "", "pathway": " (bta:493726)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "15271876;15670137;17569753;18818282;19005236;19439726;23084786;24174573;25953739", "class_list": "", "function": "A potential stage-specific regulatory role for CART in negative regulation of estradiol production associated with selection of the dominant follicle., [RefSeq, PubMed]; CART may be a novel local regulator of follicular atresia in the bovine ovary[CART], [RefSeq, PubMed]; CART peptide in the normal pancreas has been identified in intrapancreatic ganglia, nerve fibres and in endocrine cells of Langerhans islets and exocrine pancreas., [RefSeq, PubMed]; Cocaine and amphetamine regulated transcript, [RefSeq, PubMed]; DNA sequence of the complete coding region of the bovine CART gene, [RefSeq, PubMed]; Potent inhibitory effects of CART on multiple components of the follitropin signaling pathway linked to follicular development., [RefSeq, PubMed]; Satiety factor closely associated with the actions of leptin and neuropeptide y; this anorectic peptide inhibits both normal and starvation-induced feeding and completely blocks the feeding response induced by neuropeptide Y and regulated by leptin in the hypothalamus., [UniProtKB]; The intracellular mechanism of action of CART in regulation of FSH-induced MAPK signaling., [RefSeq, PubMed]; These results demonstrate hormonal regulation of granulosa cell CART binding in vitro and temporal regulation of CART binding in subordinate follicles during dominant follicle selection. Results also suggest that CART signaling may help suppress estradiol-producing capacity of the F2 (subordinate) follicle during this time period. Publication Status: Online-Only, [RefSeq, PubMed]; Two single-nucleotide polymorphisms show an association between genotype and body weight., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A4FUF3", "ec_number_list": "", "go_molecular_function": "GO:0005184 neuropeptide hormone activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0030141 secretory granule;GO:0045202 synapse", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway;GO:0007218 neuropeptide signaling pathway;GO:0043410 positive regulation of MAPK cascade;GO:0045777 positive regulation of blood pressure;GO:0007268 chemical synaptic transmission", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "Q68RJ9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q6H236-1", "uniprot_id": "PEG3_BOVIN", "mass": 264828.0, "length": 2387, "protein_name": "Paternally-expressed gene 3 protein", "gene_name": "PEG3", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "PEG3", "gene_names_refseq": "", "protein_names_uniprotkb": "Paternally-expressed gene 3 protein", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "15203203", "class_list": "", "function": "Induces apoptosis in cooperation with SIAH1A. Acts as a mediator between p53/TP53 and BAX in a neuronal death pathway that is activated by DNA damage. Acts synergistically with TRAF2 and inhibits TNF induced apoptosis through activation of NF-kappa-B (By similarity)., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0006915 apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q6H236-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q6PZ05-1", "uniprot_id": "ATG4A_BOVIN", "mass": 45354.0, "length": 398, "protein_name": "Cysteine protease ATG4A", "gene_name": "ATG4A", "organism": "Bovine", "refseq_name": "cysteine protease ATG4A", "refseq_ac": "NP_001001171", "gene_names_uniprotkb": "ATG4A; APG4A; AUT2A", "gene_names_refseq": "ATG4A; Aut2a", "protein_names_uniprotkb": "Cysteine protease ATG4A; 3.4.22.-; Autophagin-2A; Autophagy-related cysteine endopeptidase 2A; Autophagy-related protein 4 homolog A; bAut2A", "protein_names_refseq": "ATG4 autophagy related 4 homolog A; autophagin-2A; autophagy-related cysteine endopeptidase 2A; autophagy-related protein 4 homolog A; bAut2A; cysteine protease ATG4A", "tax_id": 9913, "disease": "", "pathway": " (bta:408003)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15140988", "class_list": "", "function": "(Microbial infection) Mediates cleavage of an ATG8 protein homolog coded in the genome of cytopathogenic bovine viral diarrhea virus (BVDV)., [UniProtKB, PubMed]; Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins. The protease activity is required for proteolytic activation of ATG8 family proteins: cleaves the C-terminal amino acid of ATG8 proteins to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Preferred substrate is GABARAPL2 followed by MAP1LC3A and GABARAP. Protease activity is also required to counteract formation of high-molecular weight conjugates of ATG8 proteins (ATG8ylation): acts as a deubiquitinating-like enzyme that removes ATG8 conjugated to other proteins, such as ATG3. In addition to the protease activity, also mediates delipidation of ATG8 family proteins. Catalyzes delipidation of PE-conjugated forms of ATG8 proteins during macroautophagy. Compared to ATG4B, the major protein for proteolytic activation of ATG8 proteins, shows weaker ability to cleave the C-terminal amino acid of ATG8 proteins, while it displays stronger delipidation activity. Involved in phagophore growth during mitophagy independently of its protease activity and of ATG8 proteins: acts by regulating ATG9A trafficking to mitochondria and promoting phagophore-endoplasmic reticulum contacts during the lipid transfer phase of mitophagy., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.4.22.-", "go_molecular_function": "GO:0004197 cysteine-type endopeptidase activity;GO:0008234 cysteine-type peptidase activity;GO:0019786 protein-phosphatidylethanolamide deconjugating activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0000045 autophagosome assembly;GO:0006629 lipid metabolic process;GO:0015031 protein transport;GO:0016485 protein processing;GO:0006914 autophagy", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q6PZ05-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q6T5B7-1", "uniprot_id": "AGO3_BOVIN", "mass": 97300.0, "length": 861, "protein_name": "Protein argonaute-3", "gene_name": "AGO3", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "AGO3; EIF2C3", "gene_names_refseq": "", "protein_names_uniprotkb": "Protein argonaute-3; 3.1.26.n2; Argonaute RISC catalytic component 3; Argonaute3; Eukaryotic translation initiation factor 2C 3; eIF-2C 3; eIF2C 3", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Proposed to be involved in stabilization of small RNA derivates (siRNA) derived from processed RNA polymerase III-transcribed Alu repeats containing a DR2 retinoic acid response element (RARE) in stem cells and in the subsequent siRNA-dependent degradation of a subset of RNA polymerase II-transcribed coding mRNAs by recruiting a mRNA decapping complex involving EDC4. Possesses RNA slicer activity but only on select RNAs bearing 5'- and 3'-flanking sequences to the region of guide-target complementarity (By similarity)., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0046872 metal ion binding;GO:0003727 single-stranded RNA binding;GO:0035198 miRNA binding;GO:0004521 RNA endonuclease activity;GO:0090624 endoribonuclease activity, cleaving miRNA-paired mRNA", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0000932 P-body;GO:0036464 cytoplasmic ribonucleoprotein granule;GO:0016442 RISC complex", "go_biological_process": "GO:0006402 mRNA catabolic process;GO:0031054 pre-miRNA processing;GO:0035194 regulatory ncRNA-mediated post-transcriptional gene silencing;GO:0035278 miRNA-mediated gene silencing by inhibition of translation;GO:0072091 regulation of stem cell proliferation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q6T5B7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q6TNJ1-1", "uniprot_id": "KRIT1_BOVIN", "mass": 84291.0, "length": 736, "protein_name": "Krev interaction trapped protein 1", "gene_name": "KRIT1", "organism": "Bovine", "refseq_name": "krev interaction trapped protein 1", "refseq_ac": "NP_001001166", "gene_names_uniprotkb": "KRIT1; CCM1", "gene_names_refseq": "CCM1; KRIT1", "protein_names_uniprotkb": "Krev interaction trapped protein 1; Cerebral cavernous malformations 1 protein homolog; Krev interaction trapped 1", "protein_names_refseq": "cerebral cavernous malformations 1 protein homolog; krev interaction trapped 1; krev interaction trapped protein 1", "tax_id": 9913, "disease": "", "pathway": " (bta:407996)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "17954608", "class_list": "", "function": "Component of the CCM signaling pathway which is a crucial regulator of heart and vessel formation and integrity. Negative regulator of angiogenesis. Inhibits endothelial proliferation, apoptosis, migration, lumen formation and sprouting angiogenesis in primary endothelial cells. Promotes AKT phosphorylation in a NOTCH-dependent and independent manner, and inhibits ERK1/2 phosphorylation indirectly through activation of the DELTA-NOTCH cascade. Acts in concert with CDH5 to establish and maintain correct endothelial cell polarity and vascular lumen and these effects are mediated by recruitment and activation of the Par polarity complex and RAP1B. Required for the localization of phosphorylated PRKCZ, PARD3, TIAM1 and RAP1B to the cell junction, and cell junction stabilization. Plays a role in integrin signaling via its interaction with ITGB1BP1; this prevents the interaction between ITGB1 and ITGB1BP1. Plays an important role in the maintenance of the intracellular reactive oxygen species (ROS) homeostasis to prevent oxidative cellular damage. Regulates the homeostasis of intracellular ROS through an antioxidant pathway involving FOXO1 and SOD2. Facilitates the down-regulation of cyclin-D1 (CCND1) levels required for cell transition from proliferative growth to quiescence by preventing the accumulation of intracellular ROS through the modulation of FOXO1 and SOD2 levels. Microtubule-associated protein that binds to phosphatidylinositol 4,5-bisphosphate (PIP2)-containing membranes in a GTP-bound RAP1-dependent manner (By similarity). May play a role in the regulation of macroautophagy through the down-regulation of the mTOR pathway (By similarity)., [UniProtKB, UniProtKB, UniProtKB]; Rap1 increases KRIT-1 targeting to endothelial cell-cell junctions where it suppresses stress fibers and stabilizes junctional integrity., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005546 phosphatidylinositol-4,5-bisphosphate binding;GO:0008017 microtubule binding;GO:0030695 GTPase regulator activity", "go_cellular_component": "GO:0005856 cytoskeleton;GO:0005886 plasma membrane;GO:0005911 cell-cell junction", "go_biological_process": "GO:0001525 angiogenesis;GO:0001937 negative regulation of endothelial cell proliferation;GO:2000352 negative regulation of endothelial cell apoptotic process;GO:0016525 negative regulation of angiogenesis;GO:0010596 negative regulation of endothelial cell migration", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q6TNJ1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q6VFT7-1", "uniprot_id": "FOXL2_BOVIN", "mass": 38887.0, "length": 377, "protein_name": "Forkhead box protein L2", "gene_name": "FOXL2", "organism": "Bovine", "refseq_name": "forkhead box protein L2", "refseq_ac": "NP_001026920", "gene_names_uniprotkb": "FOXL2", "gene_names_refseq": "FOXL2", "protein_names_uniprotkb": "Forkhead box protein L2", "protein_names_refseq": "forkhead box protein L2; forkhead transcription factor L2", "tax_id": 9913, "disease": "", "pathway": " (bta:281770); (R-BTA-3232118)", "pathway_count": 2, "publication_count": 4, "publication_id_list": "14684984;22623620;29281695;32098259", "class_list": "", "function": "FOXL2 is a Progesterone Target Gene in the Endometrium of Ruminants. Publication Status: Online-Only, [RefSeq, PubMed]; In vivo and in vitro experiments highlighted that neither interferon-tau nor FOXL2 were involved in transcriptional regulation of CAT, SOD1 and SOD2 Publication Status: Online-Only, [RefSeq, PubMed]; Involved in the regulation of endometrial tissue physiology Erratum:[Biol Reprod. 2012 Oct;87(4):102. Carvalho, Anais Vitorino [corrected to Vitorino Carvalho, Anais]] Publication Status: Online-Only, [RefSeq, PubMed]; Transcriptional regulator. Critical factor essential for ovary differentiation and maintenance, and repression of the genetic program for somatic testis determination (By similarity). Prevents trans-differentiation of ovary to testis through transcriptional repression of the Sertoli cell-promoting gene SOX9 (By similarity). Has apoptotic activity in ovarian cells (By similarity). Suppresses ESR1-mediated transcription of PTGS2/COX2 stimulated by tamoxifen (By similarity). Activates SIRT1 transcription under cellular stress conditions (By similarity). Activates transcription of OSR2 (By similarity). Is a regulator of CYP19 expression (By similarity). Is a transcriptional repressor of STAR (By similarity). Participates in SMAD3-dependent transcription of FST via the intronic SMAD-binding element (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q8MIM2", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0003700 DNA-binding transcription factor activity;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0031624 ubiquitin conjugating enzyme binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0030154 cell differentiation;GO:0043065 positive regulation of apoptotic process;GO:0045944 positive regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q6VFT7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q6ZXC9-1", "uniprot_id": "SIA8D_BOVIN", "mass": 41162.0, "length": 359, "protein_name": "CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase", "gene_name": "ST8SIA4", "organism": "Bovine", "refseq_name": "CMP-N-acetylneuraminate-poly-alpha-2, 8-sialyltransferase precursor", "refseq_ac": "NP_001001163", "gene_names_uniprotkb": "ST8SIA4; SIAT8D", "gene_names_refseq": "SIAT8D; ST8SIA4; ST8Sia-IV", "protein_names_uniprotkb": "CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase; 2.4.99.-; Alpha-2,8-sialyltransferase 8D; Polysialyltransferase-1; SIAT8-D; ST8SiaIV; Sialyltransferase 8D; Sialyltransferase St8Sia IV", "protein_names_refseq": "CMP-N-acetylneuraminate-poly-alpha-2, 8-sialyltransferase precursor; CMP-N-acetylneuraminate-poly-alpha-2, 8-sialyltransferase; SIAT8-D; ST8Sia IV; ST8SiaIV; alpha-2,8-sialyltransferase 8D; polysialyltransferase-1; sialyltransferase St8Sia IV; sialytransferase St8Sia IV", "tax_id": 9913, "disease": "", "pathway": " (bta:407768)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15843597", "class_list": "", "function": "Catalyzes the transfer of a sialic acid from a CMP-linked sialic acid donor onto a terminal alpha-2,3-, alpha-2,6-, or alpha-2,8-linked sialic acid of an N-linked glycan protein acceptor through alpha-2,8-linkages. Therefore, participates in polysialic acid synthesis on various sialylated N-acetyllactosaminyl oligosaccharides, including NCAM1 N-glycans, FETUB N-glycans and AHSG. It is noteworthy that alpha-2,3-linked sialic acid is apparently a better acceptor than alpha-2,6-linked sialic acid., [UniProtKB, UniProtKB]", "predicted_glycosites": 5, "predicted_n_glycosites": 5, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.4.99.-", "go_molecular_function": "GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity;GO:0008373 sialyltransferase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005576 extracellular region", "go_biological_process": "GO:0009311 oligosaccharide metabolic process;GO:0006491 N-glycan processing;GO:0097503 sialylation", "synthesized_glycan_count": 21, "hit_score": 0.2, "record_id": "Q6ZXC9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q70D51-1", "uniprot_id": "SIAT9_BOVIN", "mass": 48263.0, "length": 420, "protein_name": "Lactosylceramide alpha-2,3-sialyltransferase", "gene_name": "ST3GAL5", "organism": "Bovine", "refseq_name": "lactosylceramide alpha-2,3-sialyltransferase", "refseq_ac": "NP_991376", "gene_names_uniprotkb": "ST3GAL5; SIAT9", "gene_names_refseq": "SIAT9; ST3GAL-V; ST3GAL5", "protein_names_uniprotkb": "Lactosylceramide alpha-2,3-sialyltransferase; 2.4.3.9; CMP-NeuAc:lactosylceramide alpha-2,3-sialyltransferase; Ganglioside GM3 synthase; ST3Gal V; ST3GalV; Sialyltransferase 9", "protein_names_refseq": "CMP-NeuAc:lactosylceramide alpha-2,3-sialyltransferase; ST3Gal V; ST3GalV; alpha2,3-sialyltransferase; ganglioside GM3 synthase; lactosylceramide alpha-2,3-sialyltransferase; sialyltransferase 9", "tax_id": 9913, "disease": "", "pathway": " (bta:404164)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15843597", "class_list": "", "function": "Transfers the sialyl group (N-acetyl-alpha-neuraminyl or NeuAc) from CMP-NeuAc to the non-reducing terminal galactose (Gal) of glycosphingolipids forming gangliosides (important molecules involved in the regulation of multiple cellular processes, including cell proliferation and differentiation, apoptosis, embryogenesis, development, and oncogenesis). Mainly involved in the biosynthesis of ganglioside GM3 but can also use different glycolipids as substrate acceptors such as D-galactosylceramide (GalCer), asialo-GM2 (GA2) and asialo-GM1 (GA1), although less preferentially than beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)-Cer (LacCer)., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.4.3.9", "go_molecular_function": "GO:0047291 lactosylceramide alpha-2,3-sialyltransferase activity", "go_cellular_component": "GO:0000139 Golgi membrane", "go_biological_process": "GO:0006629 lipid metabolic process;GO:0009101 glycoprotein biosynthetic process", "synthesized_glycan_count": 412, "hit_score": 0.2, "record_id": "Q70D51-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q71SV0-1", "uniprot_id": "LAP4B_BOVIN", "mass": 25382.0, "length": 226, "protein_name": "Lysosomal-associated transmembrane protein 4B", "gene_name": "LAPTM4B", "organism": "Bovine", "refseq_name": "lysosomal-associated transmembrane protein 4B", "refseq_ac": "NP_991371", "gene_names_uniprotkb": "LAPTM4B", "gene_names_refseq": "LAPTM4B", "protein_names_uniprotkb": "Lysosomal-associated transmembrane protein 4B", "protein_names_refseq": "lysosomal associated protein transmembrane 4 beta; lysosomal-associated transmembrane protein 4B", "tax_id": 9913, "disease": "", "pathway": " (bta:404155)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "25881887", "class_list": "", "function": "Required for optimal lysosomal function. Blocks EGF-stimulated EGFR intraluminal sorting and degradation. Conversely by binding with the phosphatidylinositol 4,5-bisphosphate, regulates its PIP5K1C interaction, inhibits HGS ubiquitination and relieves LAPTM4B inhibition of EGFR degradation. Recruits SLC3A2 and SLC7A5 (the Leu transporter) to the lysosome, promoting entry of leucine and other essential amino acid (EAA) into the lysosome, stimulating activation of proton-transporting vacuolar (V)-ATPase protein pump (V-ATPase) and hence mTORC1 activation. Plays a role as negative regulator of TGFB1 production in regulatory T cells. Binds ceramide and facilitates its exit from late endosome in order to control cell death pathways., [UniProtKB, UniProtKB]; This study reports for the first time that bovine LAPTM4B in granulosa cells is present in both unubiquinated and ubiquinated forms, and is differentially expressed in developing ovarian follicles GeneRIF: LAPTM4B is differentially expressed at the mRNA and protein levels in different bovine tissues. The mRNA yields a 26.3 kDa protein that undergoes mono-ubiquitination resulting in a 31.5 kDa isoform. Immunohistochemical observations revealed that LAPTM4B expression was highly variable among tissues, and among similar and adjacent cell types. LAPTM4B may confer protection against the accumulation of metabolic byproducts. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:1902936 phosphatidylinositol bisphosphate binding;GO:0097001 ceramide binding", "go_cellular_component": "GO:0005768 endosome;GO:0005769 early endosome;GO:0005886 plasma membrane;GO:0005764 lysosome;GO:0005765 lysosomal membrane", "go_biological_process": "GO:0007032 endosome organization;GO:1905166 negative regulation of lysosomal protein catabolic process;GO:0032911 negative regulation of transforming growth factor beta1 production;GO:0032509 endosome transport via multivesicular body sorting pathway;GO:0097213 regulation of lysosomal membrane permeability", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q71SV0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q75UG4-1", "uniprot_id": "P4HA3_BOVIN", "mass": 61023.0, "length": 544, "protein_name": "Prolyl 4-hydroxylase subunit alpha-3", "gene_name": "P4HA3", "organism": "Bovine", "refseq_name": "prolyl 4-hydroxylase subunit alpha-3 precursor", "refseq_ac": "NP_001001598", "gene_names_uniprotkb": "P4HA3", "gene_names_refseq": "P4HA3", "protein_names_uniprotkb": "Prolyl 4-hydroxylase subunit alpha-3; 1.14.11.2; 4-PH alpha-3; Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-3", "protein_names_refseq": "4-PH alpha-3; Collagen prolyl 4-hydroxylase alpha III subunit; procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide III; procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-3; prolyl 4-hydroxylase subunit alpha-3 precursor", "tax_id": 9913, "disease": "", "pathway": " (bta:414348)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.14.11.2", "go_molecular_function": "GO:0005506 iron ion binding;GO:0031418 L-ascorbic acid binding;GO:0004656 procollagen-proline 4-dioxygenase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005788 endoplasmic reticulum lumen", "go_biological_process": "GO:0030199 collagen fibril organization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q75UG4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q7YRA3-1", "uniprot_id": "EXOS4_BOVIN", "mass": 26343.0, "length": 245, "protein_name": "Exosome complex component RRP41", "gene_name": "EXOSC4", "organism": "Bovine", "refseq_name": "exosome complex component RRP41", "refseq_ac": "NP_001071554", "gene_names_uniprotkb": "EXOSC4; RRP41", "gene_names_refseq": "EXOSC4; RRP41", "protein_names_uniprotkb": "Exosome complex component RRP41; Exosome component 4; Ribosomal RNA-processing protein 41", "protein_names_refseq": "exosome complex component RRP41; exosome complex exonuclease RRP41; ribosomal RNA processing protein 41", "tax_id": 9913, "disease": "", "pathway": " (bta:618292); (R-BTA-429958); (R-BTA-450385); (R-BTA-450513); (R-BTA-450604); (R-BTA-6791226); (R-BTA-9930044)", "pathway_count": 7, "publication_count": 1, "publication_id_list": "14667821", "class_list": "", "function": "Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. The RNA exosome may be involved in Ig class switch recombination (CSR) and/or Ig variable region somatic hypermutation (SHM) by targeting AICDA deamination activity to transcribed dsDNA substrates. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA. The catalytic inactive RNA exosome core complex of 9 subunits (Exo-9) is proposed to play a pivotal role in the binding and presentation of RNA for ribonucleolysis, and to serve as a scaffold for the association with catalytic subunits and accessory proteins or complexes. EXOSC4 binds to ARE-containing RNAs (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q32L11", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding;GO:0004527 exonuclease activity;GO:0035925 mRNA 3'-UTR AU-rich region binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005829 cytosol;GO:0000791 euchromatin;GO:0000176 nuclear exosome (RNase complex)", "go_biological_process": "GO:0071028 nuclear mRNA surveillance;GO:0030307 positive regulation of cell growth;GO:0000460 maturation of 5.8S rRNA;GO:0016075 rRNA catabolic process;GO:0071044 histone mRNA catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q7YRA3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q7YRZ7-1", "uniprot_id": "GRAA_BOVIN", "mass": 28070.0, "length": 258, "protein_name": "Granzyme A", "gene_name": "GZMA", "organism": "Bovine", "refseq_name": "granzyme A precursor", "refseq_ac": "NP_001001142", "gene_names_uniprotkb": "GZMA", "gene_names_refseq": "gzmA", "protein_names_uniprotkb": "Granzyme A; 3.4.21.78", "protein_names_refseq": "granzyme A precursor", "tax_id": 9913, "disease": "", "pathway": " (bta:407178)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Abundant protease in the cytosolic granules of cytotoxic T-cells and NK-cells which activates caspase-independent pyroptosis when delivered into the target cell through the immunological synapse. It cleaves after Lys or Arg. Cleaves APEX1 after 'Lys-31' and destroys its oxidative repair activity. Cleaves the nucleosome assembly protein SET after 'Lys-189', which disrupts its nucleosome assembly activity and allows the SET complex to translocate into the nucleus to nick and degrade the DNA., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004252 serine-type endopeptidase activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0043065 positive regulation of apoptotic process;GO:0031640 killing of cells of another organism;GO:0070269 pyroptotic inflammatory response;GO:0051604 protein maturation;GO:0051603 proteolysis involved in protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q7YRZ7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q7YS81-1", "uniprot_id": "MYOG_BOVIN", "mass": 24962.0, "length": 224, "protein_name": "Myogenin", "gene_name": "MYOG", "organism": "Bovine", "refseq_name": "myogenin", "refseq_ac": "NP_001104795", "gene_names_uniprotkb": "MYOG", "gene_names_refseq": "MYOG", "protein_names_uniprotkb": "Myogenin", "protein_names_refseq": "myogenin (myogenic factor 4); myogenin", "tax_id": 9913, "disease": "", "pathway": " (bta:281343); (R-BTA-525793)", "pathway_count": 2, "publication_count": 5, "publication_id_list": "22095598;26047700;28256014;28341832;29350420", "class_list": "", "function": "Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation, cell cycle exit and muscle atrophy. Essential for the development of functional embryonic skeletal fiber muscle differentiation. However is dispensable for postnatal skeletal muscle growth; phosphorylation by CAMK2G inhibits its transcriptional activity in respons to muscle activity. Required for the recruitment of the FACT complex to muscle-specific promoter regions, thus promoting gene expression initiation. During terminal myoblast differentiation, plays a role as a strong activator of transcription at loci with an open chromatin structure previously initiated by MYOD1. Together with MYF5 and MYOD1, co-occupies muscle-specific gene promoter core regions during myogenesis. Also cooperates with myocyte-specific enhancer factor MEF2D and BRG1-dependent recruitment of SWI/SNF chromatin-remodeling enzymes to alter chromatin structure at myogenic late gene promoters. Facilitates cell cycle exit during terminal muscle differentiation through the up-regulation of miR-20a expression, which in turn represses genes involved in cell cycle progression. Binds to the E-box containing (E1) promoter region of the miR-20a gene. Also plays a role in preventing reversal of muscle cell differentiation. Contributes to the atrophy-related gene expression in adult denervated muscles. Induces fibroblasts to differentiate into myoblasts (By similarity)., [UniProtKB]; Data suggested that miR-2400 could promote MDSCs proliferation through targeting MYOG, [RefSeq, PubMed]; EGR1 can promote skeletal muscle satellite cell differentiation through positive regulation of MyoG gene expression., [RefSeq, PubMed]; MiR-2425-5p targets RAD9A and MYOG to regulate the proliferation and differentiation of bovine skeletal muscle-derived satellite cells. Publication Status: Online-Only, [RefSeq, PubMed]; Overexpression of DEC1 blocked myogenesis by inhibiting MyoG promoter activity in bovine., [RefSeq, PubMed]; The MyoG SNP has potential as a genetic marker for economically relevant body measurement traits in native Chinese cattle breeds. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A7L032;Q148H1;Q1MW35", "ec_number_list": "", "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0046983 protein dimerization activity;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0031490 chromatin DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0032993 protein-DNA complex", "go_biological_process": "GO:0010831 positive regulation of myotube differentiation;GO:0014891 striated muscle atrophy;GO:0006351 DNA-templated transcription;GO:0008285 negative regulation of cell population proliferation;GO:0045944 positive regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q7YS81-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q865R1-1", "uniprot_id": "PAOX_BOVIN", "mass": 56325.0, "length": 512, "protein_name": "Peroxisomal N(1)-acetyl-spermine/spermidine oxidase", "gene_name": "PAOX", "organism": "Bovine", "refseq_name": "peroxisomal N(1)-acetyl-spermine/spermidine oxidase", "refseq_ac": "NP_001013620", "gene_names_uniprotkb": "PAOX; PAO", "gene_names_refseq": "PAOX", "protein_names_uniprotkb": "Peroxisomal N(1)-acetyl-spermine/spermidine oxidase; 1.5.3.13; Polyamine oxidase", "protein_names_refseq": "peroxisomal N(1)-acetyl-spermine/spermidine oxidase; peroxisomal N1-acetyl-spermine/spermidine oxidase", "tax_id": 9913, "disease": "", "pathway": " (bta:282639)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "12660232", "class_list": "", "function": "Flavoenzyme which catalyzes the oxidation of N(1)-acetylspermine to spermidine and is thus involved in the polyamine back-conversion. Can also oxidize N(1)-acetylspermidine to putrescine. Substrate specificity: N(1)-acetylspermine = N(1)-acetylspermidine > N(1),N(12)-diacylspermine >> spermine. Does not oxidize spermidine. Plays an important role in the regulation of polyamine intracellular concentration., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q4PS79", "ec_number_list": "1.5.3.13", "go_molecular_function": "GO:0046592 polyamine oxidase activity;GO:0052903 N(1)-acetylpolyamine oxidase (3-acetamidopropanal-forming) activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005777 peroxisome", "go_biological_process": "GO:0046203 spermidine catabolic process;GO:0008215 spermine metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q865R1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q865R3-1", "uniprot_id": "BASI_BOVIN", "mass": 22119.0, "length": 205, "protein_name": "Basigin", "gene_name": "BSG", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "BSG", "gene_names_refseq": "", "protein_names_uniprotkb": "Basigin; EMMPRIN", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "41018975", "class_list": "", "function": "Signaling receptor for cyclophilins, essential for PPIA/CYPA and PPIB/CYPB-dependent signaling related to chemotaxis and adhesion of immune cells (By similarity). Plays an important role in targeting the monocarboxylate transporters SLC16A1/GLUT1, SLC16A3, SLC16A8, SLC16A11 and SLC16A12 to the plasma membrane (By similarity). Acts as a coreceptor for vascular endothelial growth factor receptor 2 (KDR/VEGFR2) in endothelial cells enhancing its VEGFA-mediated activation and downstream signaling (By similarity). Promotes angiogenesis through EPAS1/HIF2A-mediated up-regulation of VEGFA and KDR/VEGFR2 in endothelial cells (By similarity). Plays a role in neurite outgrowth (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005537 D-mannose binding;GO:0038023 signaling receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016323 basolateral plasma membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0001525 angiogenesis;GO:0072659 protein localization to plasma membrane;GO:0010575 positive regulation of vascular endothelial growth factor production;GO:0010595 positive regulation of endothelial cell migration;GO:0061154 endothelial tube morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q865R3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q865V0-1", "uniprot_id": "CEP57_BOVIN", "mass": 56986.0, "length": 499, "protein_name": "Centrosomal protein of 57 kDa", "gene_name": "CEP57", "organism": "Bovine", "refseq_name": "centrosomal protein of 57 kDa", "refseq_ac": "NP_852115", "gene_names_uniprotkb": "CEP57; TSP57", "gene_names_refseq": "CEP57", "protein_names_uniprotkb": "Centrosomal protein of 57 kDa; Cep57; Testis-specific protein 57; Translokin", "protein_names_refseq": "centrosomal protein of 57 kDa; testis-specific protein 57; translokin", "tax_id": 9913, "disease": "", "pathway": " (bta:353245)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "12717444", "class_list": "", "function": "Centrosomal protein which may be required for microtubule attachment to centrosomes. May act by forming ring-like structures around microtubules. Mediates nuclear translocation and mitogenic activity of the internalized growth factor FGF2 (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q32L39", "ec_number_list": "", "go_molecular_function": "GO:0008017 microtubule binding;GO:0042803 protein homodimerization activity;GO:0017134 fibroblast growth factor binding;GO:0043015 gamma-tubulin binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005813 centrosome;GO:0005874 microtubule", "go_biological_process": "GO:0008543 fibroblast growth factor receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q865V0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q867A9-1", "uniprot_id": "EDN2_BOVIN", "mass": 19706.0, "length": 177, "protein_name": "Endothelin-2", "gene_name": "EDN2", "organism": "Bovine", "refseq_name": "endothelin-2 precursor", "refseq_ac": "NP_783645", "gene_names_uniprotkb": "EDN2", "gene_names_refseq": "EDN2", "protein_names_uniprotkb": "Endothelin-2; ET-2; PPET2; Preproendothelin-2", "protein_names_refseq": "ET-2; PPET2; endothelin-2 precursor; preproendothelin-2", "tax_id": 9913, "disease": "", "pathway": " (bta:319094); (R-BTA-375276); (R-BTA-416476)", "pathway_count": 3, "publication_count": 2, "publication_id_list": "14756425;32881967", "class_list": "", "function": "Endothelins are endothelium-derived vasoconstrictor peptides., [UniProtKB]; The EDN2 rs110287192 gene polymorphism is associated with paratuberculosis susceptibility in multibreed cattle population. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005179 hormone activity;GO:0031708 endothelin B receptor binding", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0045987 positive regulation of smooth muscle contraction;GO:0006874 intracellular calcium ion homeostasis;GO:0019229 regulation of vasoconstriction;GO:0003100 regulation of systemic arterial blood pressure by endothelin;GO:0014826 vein smooth muscle contraction", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q867A9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q8HZT6-1", "uniprot_id": "RDH10_BOVIN", "mass": 38087.0, "length": 341, "protein_name": "Retinol dehydrogenase 10", "gene_name": "RDH10", "organism": "Bovine", "refseq_name": "retinol dehydrogenase 10", "refseq_ac": "NP_777159", "gene_names_uniprotkb": "RDH10", "gene_names_refseq": "RDH10", "protein_names_uniprotkb": "Retinol dehydrogenase 10; 1.1.1.300", "protein_names_refseq": "retinol dehydrogenase 10 (all-trans); retinol dehydrogenase 10", "tax_id": 9913, "disease": "", "pathway": " (bta:282852); (R-BTA-2453902); (R-BTA-5365859)", "pathway_count": 3, "publication_count": 2, "publication_id_list": "12407145;15505029", "class_list": "", "function": "Retinol dehydrogenase with a clear preference for NADP. Converts all-trans-retinol to all-trans-retinal. Has no detectable activity towards 11-cis-retinol, 9-cis-retinol and 13-cis-retinol (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.1.1.300;1.1.1.21;1.1.1.372;1.1.1.54;1.1.1.105;1.1.1.209;1.1.1.53;1.1.1.184", "go_molecular_function": "GO:0004745 all-trans-retinol dehydrogenase (NAD+) activity;GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0052650 all-trans-retinol dehydrogenase (NADP+) activity", "go_cellular_component": "GO:0005811 lipid droplet;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0042574 retinal metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q8HZT6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q8MI01-1", "uniprot_id": "MUC15_BOVIN", "mass": 35715.0, "length": 330, "protein_name": "Mucin-15", "gene_name": "MUC15", "organism": "Bovine", "refseq_name": "mucin-15 precursor", "refseq_ac": "NP_788804", "gene_names_uniprotkb": "MUC15", "gene_names_refseq": "MUC15", "protein_names_uniprotkb": "Mucin-15; Component II; Glycoprotein 4; Glycoprotein C; MUC-15; PAS3; PASIII", "protein_names_refseq": "MUC-15; PAS3; PASIII; component II; glycoprotein 4; glycoprotein C; mucin-15 precursor; mucin-15", "tax_id": 9913, "disease": "", "pathway": " (bta:337919)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "12047385", "class_list": "", "function": "", "predicted_glycosites": 4, "predicted_n_glycosites": 4, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 11, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 11, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 11, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 15, "binding_glycan_count": 0, "secondary_ac_list": "Q8MI16", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005576 extracellular region;GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "Q8MI01-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q8MIU0-1", "uniprot_id": "TYRO_BOVIN", "mass": 60304.0, "length": 530, "protein_name": "Tyrosinase", "gene_name": "TYR", "organism": "Bovine", "refseq_name": "tyrosinase precursor", "refseq_ac": "NP_851344", "gene_names_uniprotkb": "TYR", "gene_names_refseq": "TYR", "protein_names_uniprotkb": "Tyrosinase; 1.14.18.1; Monophenol monooxygenase", "protein_names_refseq": "monophenol monooxygenase; tyrosinase (oculocutaneous albinism IA); tyrosinase precursor", "tax_id": 9913, "disease": "", "pathway": " (bta:280951)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "14727143", "class_list": "", "function": "This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds (By similarity). Catalyzes the initial and rate limiting step in the cascade of reactions leading to melanin production from tyrosine (By similarity). In addition to hydroxylating tyrosine to DOPA (3,4-dihydroxyphenylalanine), also catalyzes the oxidation of DOPA to DOPA-quinone, and possibly the oxidation of DHI (5,6-dihydroxyindole) to indole-5,6 quinone (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 5, "predicted_n_glycosites": 5, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "Q8WN56", "ec_number_list": "1.14.18.1;1.14.18.-", "go_molecular_function": "GO:0042803 protein homodimerization activity;GO:0046872 metal ion binding;GO:0004503 tyrosinase activity", "go_cellular_component": "GO:0042470 melanosome;GO:0033162 melanosome membrane", "go_biological_process": "GO:0043473 pigmentation;GO:0042438 melanin biosynthetic process;GO:0009637 response to blue light", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q8MIU0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q8MJ08-1", "uniprot_id": "PE2R4_BOVIN", "mass": 53298.0, "length": 492, "protein_name": "Prostaglandin E2 receptor EP4 subtype", "gene_name": "PTGER4", "organism": "Bovine", "refseq_name": "prostaglandin E2 receptor EP4 subtype", "refseq_ac": "NP_777014", "gene_names_uniprotkb": "PTGER4", "gene_names_refseq": "PTGER4; ep4", "protein_names_uniprotkb": "Prostaglandin E2 receptor EP4 subtype; PGE receptor EP4 subtype; PGE2 receptor EP4 subtype; Prostanoid EP4 receptor", "protein_names_refseq": "PGE receptor, EP4 subtype; PGE2 receptor EP4 subtype; prostaglandin E receptor 4 (subtype EP4); prostaglandin E2 receptor EP4 subtype; prostanoid EP4 receptor", "tax_id": 9913, "disease": "", "pathway": " (bta:282331)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "12810564;19261969;25001909;26319698;26482178", "class_list": "", "function": "Data suggest that estradiol up-regulates mRNA and protein expression of 3 prostanoid receptors in oviduct smooth muscle: EP2/PTGER2 (prostaglandin E receptor 2); EP4/PTGER4 (prostaglandin E receptor 4); and FP/PTGFR (prostaglandin F2alpha receptor)., [RefSeq, PubMed]; Data suggest that lysophosphatidic acid (LPA) up-regulates expression of SLCO2A1 (prostaglandin [PG] transporter), PTGER2/PTGER4 (PG receptors EP2/EP4), and mPGES1/cPGES (microsomal/cytosolic PG E synthases) in luteal cells., [RefSeq, PubMed]; EP4 is undetectable in endometrium and myometrium during the estrous cycle, [RefSeq, PubMed]; Quantitative RT-PCR revealed significant higher expression of EP2 and EP4 in the pre-ovulatory phase compared with the luteal phase in the bovine oviduct, [RefSeq, PubMed]; Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. Has a relaxing effect on smooth muscle. May play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function (By similarity)., [UniProtKB]; The PGE2-mediated down-regulation of CD25 expression on T cells is mediated via the EP4 receptor, although selective activation of the EP2 receptor up-regulates the CD25 expression on these cells., [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004957 prostaglandin E receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0033624 negative regulation of integrin activation;GO:0006954 inflammatory response;GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007204 positive regulation of cytosolic calcium ion concentration;GO:0050728 negative regulation of inflammatory response", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q8MJ08-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q8MJ24-1", "uniprot_id": "LOXL4_BOVIN", "mass": 84050.0, "length": 757, "protein_name": "Lysyl oxidase homolog 4", "gene_name": "LOXL4", "organism": "Bovine", "refseq_name": "lysyl oxidase homolog 4 precursor", "refseq_ac": "NP_776809", "gene_names_uniprotkb": "LOXL4", "gene_names_refseq": "LOXL4", "protein_names_uniprotkb": "Lysyl oxidase homolog 4; 1.4.3.13; Lysyl oxidase-like protein 4", "protein_names_refseq": "lysyl oxidase homolog 4 precursor; lysyl oxidase homolog 4; lysyl oxidase-like protein 4", "tax_id": 9913, "disease": "", "pathway": " (bta:281904)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23572561", "class_list": "", "function": "Catalyzes the oxidative deamination of lysine and hydroxylysine residues in collagen and elastin, resulting in the formation of covalent cross-linkages, and the stabilization of collagen and elastin fibers., [UniProtKB, UniProtKB]; These results suggest that TGF-beta1-dependent expression of LOXL4 plays a role in vascular extracellular matrix homeostasis, contributing to vascular processes associated with extracellular matrix remodeling and fibrosis., [RefSeq, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.4.3.13", "go_molecular_function": "GO:0005507 copper ion binding;GO:0004720 protein-lysine 6-oxidase activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0016020 membrane;GO:0031012 extracellular matrix", "go_biological_process": "GO:0030199 collagen fibril organization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q8MJ24-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q8MJG0-1", "uniprot_id": "R9BP_BOVIN", "mass": 25709.0, "length": 237, "protein_name": "Regulator of G protein signaling 9-binding protein", "gene_name": "RGS9BP", "organism": "Bovine", "refseq_name": "regulator of G-protein signaling 9-binding protein", "refseq_ac": "NP_001159988", "gene_names_uniprotkb": "RGS9BP; R9AP", "gene_names_refseq": "RGS9BP", "protein_names_uniprotkb": "Regulator of G protein signaling 9-binding protein; RGS9-anchoring protein", "protein_names_refseq": "RGS9-anchoring protein; regulator of G-protein signaling 9-binding protein; regulator of G-protein signalling 9 binding protein", "tax_id": 9913, "disease": "", "pathway": " (bta:282338); (R-BTA-2514859)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "12119397;12560335", "class_list": "", "function": "Regulator of G protein-coupled receptor (GPCR) signaling in phototransduction. Participates in the recovery phase of visual transduction via its interaction with RGS9-1 isoform. Acts as a membrane-anchor that mediates the targeting of RGS9-1 to the photoreceptor outer segment, where phototransduction takes place. Enhances the ability of RGS9-1 to stimulate G protein GTPase activity, allowing the visual signal to be terminated on the physiologically time scale. It also controls the proteolytic stability of RGS9-1, probably by protecting it from degradation (By similarity)., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0043005 neuron projection;GO:0097381 photoreceptor disc membrane", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway;GO:0009968 negative regulation of signal transduction;GO:0050908 detection of light stimulus involved in visual perception", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q8MJG0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q8MJJ7-1", "uniprot_id": "DCPS_BOVIN", "mass": 38402.0, "length": 337, "protein_name": "m7GpppX diphosphatase", "gene_name": "DCPS", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "DCPS; DCS1; HINT5", "gene_names_refseq": "", "protein_names_uniprotkb": "m7GpppX diphosphatase; 3.6.1.59; DCS-1; Decapping scavenger enzyme; HINT-5; Hint-related 7meGMP-directed hydrolase; Histidine triad nucleotide-binding protein 5; Histidine triad protein member 5; Scavenger mRNA-decapping enzyme DcpS", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Decapping scavenger enzyme that catalyzes the cleavage of a residual cap structure following the degradation of mRNAs by 3'->5' exosome-mediated mRNA decay pathway. Hydrolyzes cap analog structures like 7-methylguanosine nucleoside triphosphate (m7GpppG) with up to 10 nucleotide substrates (small capped oligoribonucleotides) and specifically releases 5'-phosphorylated RNA fragments and 7-methylguanosine monophosphate (m7GMP). Cleaves cap analog structures like tri-methyl guanosine nucleoside triphosphate (m3(2,2,7)GpppG) with very poor efficiency. Does not hydrolyze unmethylated cap analog (GpppG) and shows no decapping activity on intact m7GpppG-capped mRNA molecules longer than 25 nucleotides. Does not hydrolyze 7-methylguanosine diphosphate (m7GDP) to m7GMP. May also play a role in the 5'->3 mRNA decay pathway; m7GDP, the downstream product released by the 5'->3' mRNA mediated decapping activity, may be also converted by DCPS to m7GMP. Binds to m7GpppG and strongly to m7GDP. Plays a role in first intron splicing of pre-mRNAs. Inhibits activation-induced cell death., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.6.1.59;3.6.1.52;3.6.1.62;3.6.1.10;3.6.1.61", "go_molecular_function": "GO:0000340 RNA 7-methylguanosine cap binding;GO:0140932 5'-(N(7)-methyl 5'-triphosphoguanosine)-[mRNA] diphosphatase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0000932 P-body", "go_biological_process": "GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA;GO:0045292 mRNA cis splicing, via spliceosome", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q8MJJ7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q8MJK1-1", "uniprot_id": "CBY1_BOVIN", "mass": 14509.0, "length": 127, "protein_name": "Protein chibby homolog 1", "gene_name": "CBY1", "organism": "Bovine", "refseq_name": "protein chibby homolog 1", "refseq_ac": "NP_777164", "gene_names_uniprotkb": "CBY1; CBY; PGEA1", "gene_names_refseq": "CBY1", "protein_names_uniprotkb": "Protein chibby homolog 1; Cytosolic leucine-rich protein; PIGEA-14; PKD2 interactor, Golgi and endoplasmic reticulum-associated 1", "protein_names_refseq": "PIGEA-14; PKD2 interactor, Golgi and endoplasmic reticulum-associated 1; cytosolic leucine-rich protein; protein chibby homolog 1", "tax_id": 9913, "disease": "", "pathway": " (bta:282859); (R-BTA-3769402)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Inhibits the Wnt/Wingless pathway by binding to CTNNB1/beta-catenin and inhibiting beta-catenin-mediated transcriptional activation through competition with TCF/LEF transcription factors. Has also been shown to play a role in regulating the intracellular trafficking of polycystin-2/PKD2 and possibly of other intracellular proteins. Promotes adipocyte and cardiomyocyte differentiation., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q0P5H0", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005794 Golgi apparatus;GO:0016607 nuclear speck;GO:0036126 sperm flagellum;GO:0005814 centriole", "go_biological_process": "GO:0045444 fat cell differentiation;GO:0030178 negative regulation of Wnt signaling pathway;GO:0055007 cardiac muscle cell differentiation;GO:0030030 cell projection organization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q8MJK1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q8SPU5-1", "uniprot_id": "BPIA1_BOVIN", "mass": 26576.0, "length": 255, "protein_name": "BPI fold-containing family A member 1", "gene_name": "BPIFA1", "organism": "Bovine", "refseq_name": "BPI fold-containing family A member 1 precursor", "refseq_ac": "NP_776851", "gene_names_uniprotkb": "BPIFA1; PLUNC", "gene_names_refseq": "BPIFA1; PLUNC; SPLUNC1", "protein_names_uniprotkb": "BPI fold-containing family A member 1; Palate lung and nasal epithelium clone protein", "protein_names_refseq": "BPI fold-containing family A member 1 precursor; palate lung and nasal epithelium clone protein; palate, lung and nasal epithelium associated; palate, lung and nasal epithelium carcinoma associated; protein Plunc", "tax_id": 9913, "disease": "", "pathway": " (bta:281989); (R-BTA-6803157)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "12427544", "class_list": "", "function": "Lipid-binding protein which shows high specificity for the surfactant phospholipid dipalmitoylphosphatidylcholine (DPPC). Plays a role in the innate immune responses of the upper airways. Reduces the surface tension in secretions from airway epithelia and inhibits the formation of biofilm by pathogenic Gram-negative bacteria, such as P.aeruginosa and K.pneumoniae. Negatively regulates proteolytic cleavage of SCNN1G, an event that is required for activation of the epithelial sodium channel (ENaC), and thereby contributes to airway surface liquid homeostasis and proper clearance of mucus. Plays a role in the airway inflammatory response after exposure to irritants. May attract macrophages and neutrophils., [UniProtKB, UniProtKB]", "predicted_glycosites": 4, "predicted_n_glycosites": 3, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "Q1RMN7", "ec_number_list": "", "go_molecular_function": "GO:0008289 lipid binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0005615 extracellular space", "go_biological_process": "GO:0019731 antibacterial humoral response;GO:0043129 surfactant homeostasis;GO:0045087 innate immune response;GO:0051607 defense response to virus;GO:0061844 antimicrobial humoral immune response mediated by antimicrobial peptide", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q8SPU5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9N0T5-1", "uniprot_id": "IF4E_BOVIN", "mass": 25079.0, "length": 217, "protein_name": "Eukaryotic translation initiation factor 4E", "gene_name": "EIF4E", "organism": "Bovine", "refseq_name": "eukaryotic translation initiation factor 4E", "refseq_ac": "NP_776735", "gene_names_uniprotkb": "EIF4E", "gene_names_refseq": "EIF4E", "protein_names_uniprotkb": "Eukaryotic translation initiation factor 4E; eIF-4E; eIF4E; mRNA cap-binding protein", "protein_names_refseq": "eIF-4E; eukaryotic translation initiation factor 4E; mRNA cap-binding protein", "tax_id": 9913, "disease": "", "pathway": " (bta:281751); (R-BTA-1169408); (R-BTA-156827); (R-BTA-159227); (R-BTA-159230); (R-BTA-159231); (R-BTA-166208); (R-BTA-429947); (R-BTA-72649); (R-BTA-72662); (R-BTA-72702)", "pathway_count": 11, "publication_count": 2, "publication_id_list": "11913777;26055918", "class_list": "", "function": "Acts in the cytoplasm to initiate and regulate protein synthesis and is required in the nucleus for export of a subset of mRNAs from the nucleus to the cytoplasm which promotes processes such as RNA capping, processing and splicing (By similarity). Component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure and recruitment of mRNA to the ribosome (By similarity). This protein recognizes and binds the 7-methylguanosine (m7G)-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures (By similarity). Together with EIF4G1, antagonizes the scanning promoted by EIF1-EIF4G1 and is required for TISU translation, a process where the TISU element recognition makes scanning unnecessary (By similarity). In addition to its role in translation initiation, also acts as a regulator of translation and stability in the cytoplasm. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression: in the complex, EIF4E mediates the binding to the mRNA cap. Component of a multiprotein complex that sequesters and represses translation of proneurogenic factors during neurogenesis (By similarity). In P-bodies, component of a complex that mediates the storage of translationally inactive mRNAs in the cytoplasm and prevents their degradation (By similarity). May play an important role in spermatogenesis through translational regulation of stage-specific mRNAs during germ cell development (By similarity). As well as its roles in translation, also involved in mRNA nucleocytoplasmic transport (By similarity). Its role in mRNA export from the nucleus to the cytoplasm relies on its ability to bind the m7G cap of RNAs and on the presence of the 50-nucleotide EIF4E sensitivity element (4ESE) in the 3'UTR of sensitive transcripts (By similarity). Interaction with the 4ESE is mediated by LRPPRC which binds simultaneously to both EIF4E and the 4ESE, thereby acting as a platform for assembly for the RNA export complex (By similarity). EIF4E-dependent mRNA export is independent of ongoing protein or RNA synthesis and is also NFX1-independent but is XPO1-dependent with LRPPRC interacting with XPO1 to form an EIF4E-dependent mRNA export complex (By similarity). Alters the composition of the cytoplasmic face of the nuclear pore to promote RNA export by reducing RANBP2 expression, relocalizing nucleoporin NUP214 and increasing expression of RANBP1 and RNA export factors DDX19 and GLE1. Promotes the nuclear export of cyclin CCND1 mRNA (By similarity). Promotes the nuclear export of NOS2/iNOS mRNA (By similarity). Promotes the nuclear export of MDM2 mRNA (By similarity). Also promotes the export of additional mRNAs, including others involved in the cell cycle (By similarity). In the nucleus, binds to capped splice factor-encoding mRNAs and stimulates their nuclear export to enhance splice factor production by increasing their cytoplasmic availability to the translation machinery (By similarity). May also regulate splicing through interaction with the spliceosome in an RNA and m7G cap-dependent manner (By similarity). Also binds to some pre-mRNAs and may play a role in their recruitment to the spliceosome (By similarity). Promotes steady-state capping of a subset of coding and non-coding RNAs by mediating nuclear export of capping machinery mRNAs including RNMT, RNGTT and RAMAC to enhance their translation (By similarity). Stimulates mRNA 3'-end processing by promoting the expression of several core cleavage complex factors required for mRNA cleavage and polyadenylation, and may also have a direct effect through its interaction with the CPSF3 cleavage enzyme (By similarity). Rescues cells from apoptosis by promoting activation of serine/threonine-protein kinase AKT1 through mRNA export of NBS1 which potentiates AKT1 phosphorylation and also through mRNA export of AKT1 effectors, allowing for increased production of these proteins (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q2NL02", "ec_number_list": "", "go_molecular_function": "GO:0019899 enzyme binding;GO:0000340 RNA 7-methylguanosine cap binding;GO:0003743 translation initiation factor activity;GO:0098808 mRNA cap binding;GO:0031370 eukaryotic initiation factor 4G binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0016607 nuclear speck;GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "GO:0006406 mRNA export from nucleus;GO:0006417 regulation of translation;GO:0006413 translational initiation;GO:0051028 mRNA transport;GO:0045931 positive regulation of mitotic cell cycle", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q9N0T5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q8SQB8-1", "uniprot_id": "ITB6_BOVIN", "mass": 85893.0, "length": 788, "protein_name": "Integrin beta-6", "gene_name": "ITGB6", "organism": "Bovine", "refseq_name": "integrin beta-6 isoform 1 precursor", "refseq_ac": "NP_777123", "gene_names_uniprotkb": "ITGB6", "gene_names_refseq": "ITGB6", "protein_names_uniprotkb": "Integrin beta-6", "protein_names_refseq": "integrin beta-6 isoform 1 precursor; integrin, beta 6", "tax_id": 9913, "disease": "", "pathway": " (bta:282644); (R-BTA-1566948); (R-BTA-2129379); (R-BTA-216083); (R-BTA-2173789); (R-BTA-3000178)", "pathway_count": 6, "publication_count": 4, "publication_id_list": "12551988;15331710;18045932;25078391", "class_list": "", "function": "Identified as receptor for foot-and-mouth disease virus, [RefSeq, PubMed]; Integrin alpha-V:beta-6 (ITGAV:ITGB6) is a receptor for fibronectin and cytotactin (By similarity). It recognizes the sequence R-G-D in its ligands (By similarity). ITGAV:ITGB6 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1 (By similarity). Integrin alpha-V:beta-6 (ITGAV:ITGB6) mediates R-G-D-dependent release of transforming growth factor beta-1 (TGF-beta-1) from regulatory Latency-associated peptide (LAP), thereby playing a key role in TGF-beta-1 activation (By similarity)., [UniProtKB, UniProtKB, UniProtKB]; Integrin alpha-V:beta-6 (ITGAV:ITGB6) is a receptor for fibronectin and cytotactin. It recognizes the sequence R-G-D in its ligands. ITGAV:ITGB6 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1. Integrin alpha-V:beta-6 (ITGAV:ITGB6) mediates R-G-D-dependent release of transforming growth factor beta-1 (TGF-beta-1) from regulatory Latency-associated peptide (LAP), thereby playing a key role in TGF-beta-1 activation., [UniProtKB, UniProtKB, UniProtKB]; Single-nucleotide polymorphism G29A in ITGB6 (rs109075046) revealed a clear role in the incidence of foot-and-mouth disease in the studied population., [RefSeq, PubMed]; Specific substitutions show that the stable binding between foot-and-mouth disease virus VP1 and integrin alphavbeta6 is dependent on a helical structure and, specifically, two leucine residues at positions +1 and RGD +4 from the RGD motif., [RefSeq, PubMed]", "predicted_glycosites": 10, "predicted_n_glycosites": 9, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 10, "binding_glycan_count": 0, "secondary_ac_list": "Q0PE61", "ec_number_list": "", "go_molecular_function": "GO:0005178 integrin binding;GO:0015026 coreceptor activity;GO:0046872 metal ion binding;GO:0001618 virus receptor activity;GO:0140677 molecular function activator activity", "go_cellular_component": "GO:0005925 focal adhesion;GO:0009986 cell surface;GO:0009897 external side of plasma membrane;GO:0034685 integrin alphav-beta6 complex;GO:0005886 plasma membrane", "go_biological_process": "GO:0007229 integrin-mediated signaling pathway;GO:0016477 cell migration;GO:0007160 cell-matrix adhesion;GO:0033627 cell adhesion mediated by integrin;GO:0098609 cell-cell adhesion", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q8SQB8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9TU47-1", "uniprot_id": "IF6_BOVIN", "mass": 26513.0, "length": 245, "protein_name": "Eukaryotic translation initiation factor 6", "gene_name": "EIF6", "organism": "Bovine", "refseq_name": "eukaryotic translation initiation factor 6", "refseq_ac": "NP_777255", "gene_names_uniprotkb": "EIF6; ITGB4BP", "gene_names_refseq": "EIF6; ITGB4BP", "protein_names_uniprotkb": "Eukaryotic translation initiation factor 6; Imc-415 homolog; eIF-6", "protein_names_refseq": "eIF-6; eukaryotic translation initiation factor 6; imc-415 homolog; integrin beta 4 binding protein", "tax_id": 9913, "disease": "", "pathway": " (bta:286811)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "10879479;29543378", "class_list": "", "function": "Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)-dependent protein kinase C activity. In tissues responsive to insulin, controls fatty acid synthesis and glycolysis by exerting translational control of adipogenic transcription factors such as CEBPB, CEBPD and ATF4 that have G/C rich or uORF in their 5'UTR. Required for ROS-dependent megakaryocyte maturation and platelets formation, controls the expression of mitochondrial respiratory chain genes involved in reactive oxygen species (ROS) synthesis. Involved in miRNA-mediated gene silencing by the RNA-induced silencing complex (RISC). Required for both miRNA-mediated translational repression and miRNA-mediated cleavage of complementary mRNAs by RISC. Modulates cell cycle progression and global translation of pre-B cells, its activation seems to be rate-limiting in tumorigenesis and tumor growth., [UniProtKB, HAMAP, UniProtKB, UniProtKB, UniProtKB]; The C-terminus amino acids 147 to 174 of Bovine adenovirus-3 protein VIII and N-terminus amino acids 44 to 97 of bovine eIF6 are involved in these interactions., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 8, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q2TBM1", "ec_number_list": "", "go_molecular_function": "GO:0003743 translation initiation factor activity;GO:0043023 ribosomal large subunit binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005730 nucleolus;GO:0005829 cytosol;GO:0005654 nucleoplasm;GO:0005737 cytoplasm", "go_biological_process": "GO:0006110 regulation of glycolytic process;GO:0042304 regulation of fatty acid biosynthetic process;GO:0000054 ribosomal subunit export from nucleus;GO:0032868 response to insulin;GO:0045652 regulation of megakaryocyte differentiation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q9TU47-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q1JPJ2-1", "uniprot_id": "XPP1_BOVIN", "mass": 69790.0, "length": 623, "protein_name": "Xaa-Pro aminopeptidase 1", "gene_name": "XPNPEP1", "organism": "Bovine", "refseq_name": "xaa-Pro aminopeptidase 1", "refseq_ac": "NP_001069070", "gene_names_uniprotkb": "XPNPEP1", "gene_names_refseq": "XPNPEP1", "protein_names_uniprotkb": "Xaa-Pro aminopeptidase 1; 3.4.11.9; Aminoacylproline aminopeptidase; Cytosolic aminopeptidase P; Soluble aminopeptidase P; X-Pro aminopeptidase 1; X-prolyl aminopeptidase 1, soluble; sAmp", "protein_names_refseq": "X-Pro aminopeptidase 1; X-prolyl aminopeptidase (aminopeptidase P) 1, soluble; X-prolyl aminopeptidase 1, soluble; aminoacylproline aminopeptidase; cytosolic aminopeptidase P; sAmp; soluble aminopeptidase P; xaa-Pro aminopeptidase 1", "tax_id": 9913, "disease": "", "pathway": " (bta:513156)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "Metalloaminopeptidase that catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides, such as Arg-Pro-Pro. Contributes to the degradation of bradykinin., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0030145 manganese ion binding;GO:0070006 metalloaminopeptidase activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005829 cytosol;GO:0005737 cytoplasm", "go_biological_process": "GO:0006508 proteolysis;GO:0043069 negative regulation of programmed cell death;GO:0010815 bradykinin catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q1JPJ2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KIS7-1", "uniprot_id": "TETN_BOVIN", "mass": 22144.0, "length": 202, "protein_name": "Tetranectin", "gene_name": "CLEC3B", "organism": "Bovine", "refseq_name": "tetranectin precursor", "refseq_ac": "NP_001039677", "gene_names_uniprotkb": "CLEC3B", "gene_names_refseq": "CLEC3B", "protein_names_uniprotkb": "Tetranectin; C-type lectin domain family 3 member B; TN", "protein_names_refseq": "TN; tetranectin precursor; tetranectin", "tax_id": 9913, "disease": "", "pathway": " (bta:515783); (R-BTA-114608)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Tetranectin binds to plasminogen and to isolated kringle 4. May be involved in the packaging of molecules destined for exocytosis (By similarity). Plays a role in retinal function (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008201 heparin binding;GO:0005509 calcium ion binding;GO:0030246 carbohydrate binding;GO:0036143 kringle domain binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005737 cytoplasm;GO:0001652 granular component", "go_biological_process": "GO:0010756 positive regulation of plasminogen activation;GO:0001503 ossification;GO:0030282 bone mineralization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2KIS7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KJ39-1", "uniprot_id": "RCN3_BOVIN", "mass": 37568.0, "length": 328, "protein_name": "Reticulocalbin-3", "gene_name": "RCN3", "organism": "Bovine", "refseq_name": "reticulocalbin-3 precursor", "refseq_ac": "NP_001039725", "gene_names_uniprotkb": "RCN3", "gene_names_refseq": "RCN3", "protein_names_uniprotkb": "Reticulocalbin-3", "protein_names_refseq": "reticulocalbin 3, EF-hand calcium binding domain; reticulocalbin-3 precursor", "tax_id": 9913, "disease": "", "pathway": " (bta:522073)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Probable molecular chaperone assisting protein biosynthesis and transport in the endoplasmic reticulum. Required for the proper biosynthesis and transport of pulmonary surfactant-associated protein A/SP-A, pulmonary surfactant-associated protein D/SP-D and the lipid transporter ABCA3. By regulating both the proper expression and the degradation through the endoplasmic reticulum-associated protein degradation pathway of these proteins plays a crucial role in pulmonary surfactant homeostasis. Has an anti-fibrotic activity by negatively regulating the secretion of type I and type III collagens. This calcium-binding protein also transiently associates with immature PCSK6 and regulates its secretion., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005788 endoplasmic reticulum lumen", "go_biological_process": "GO:0015031 protein transport;GO:0043129 surfactant homeostasis;GO:0055091 phospholipid homeostasis;GO:0009306 protein secretion;GO:0036503 ERAD pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2KJ39-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q29RL0-1", "uniprot_id": "TBC31_BOVIN", "mass": 123866.0, "length": 1063, "protein_name": "TBC1 domain family member 31", "gene_name": "TBC1D31", "organism": "Bovine", "refseq_name": "TBC1 domain family member 31", "refseq_ac": "NP_001039538", "gene_names_uniprotkb": "TBC1D31", "gene_names_refseq": "TBC1D31; WDR67", "protein_names_uniprotkb": "TBC1 domain family member 31", "protein_names_refseq": "TBC1 domain family member 31; WD repeat domain 67; WD repeat-containing protein 67", "tax_id": 9913, "disease": "", "pathway": " (bta:511062)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Molecular adapter which is involved in cilium biogenesis. Part of a functional complex including OFD1 a centriolar protein involved in cilium assembly. Could regulate the cAMP-dependent phosphorylation of OFD1, and its subsequent ubiquitination by PJA2 which ultimately leads to its proteasomal degradation., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0060090 molecular adaptor activity", "go_cellular_component": "GO:0005813 centrosome;GO:0034451 centriolar satellite;GO:0036064 ciliary basal body", "go_biological_process": "GO:0060271 cilium assembly", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q29RL0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q1LZC9-1", "uniprot_id": "DPH3_BOVIN", "mass": 9288.0, "length": 82, "protein_name": "Diphthamide biosynthesis protein 3", "gene_name": "DPH3", "organism": "Bovine", "refseq_name": "diphthamide biosynthesis protein 3 isoform 1", "refseq_ac": "NP_001106770", "gene_names_uniprotkb": "DPH3; ZCSL2", "gene_names_refseq": "DPH3", "protein_names_uniprotkb": "Diphthamide biosynthesis protein 3; CSL-type zinc finger-containing protein 2", "protein_names_refseq": "CSL-type zinc finger-containing protein 2; DPH3, KTI11 homolog; diphthamide biosynthesis protein 3 isoform 1; diphthamide biosynthesis protein 3; zinc finger, CSL domain containing 2", "tax_id": 9913, "disease": "", "pathway": " (bta:511579); (R-BTA-5358493)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Required for the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2. DPH1 and DPH2 transfer a 3-amino-3-carboxypropyl (ACP) group from S-adenosyl-L-methionine (SAM) to a histidine residue, the reaction is assisted by a reduction system comprising DPH3 and a NADH-dependent reductase. Acts as an electron donor to reduce the Fe-S cluster in DPH1-DPH2 keeping the [4Fe-4S] clusters in the active and reduced state. Restores iron to DPH1-DPH2 iron-sulfur clusters which have degraded from [4Fe-4S] to [3Fe-4S] by donating an iron atom to reform [4Fe-4S] clusters, in a manner dependent on the presence of elongation factor 2 and SAM. Associates with the elongator complex and is required for tRNA Wobble base modifications mediated by the elongator complex. The elongator complex is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s 2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005506 iron ion binding;GO:0008198 ferrous iron binding;GO:0034986 iron chaperone activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0032991 protein-containing complex", "go_biological_process": "GO:0050709 negative regulation of protein secretion;GO:0017183 protein histidyl modification to diphthamide;GO:0002926 tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q1LZC9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KII7-1", "uniprot_id": "PEX16_BOVIN", "mass": 37574.0, "length": 328, "protein_name": "Peroxisomal membrane protein PEX16", "gene_name": "PEX16", "organism": "Bovine", "refseq_name": "peroxisomal biogenesis factor 16", "refseq_ac": "NP_001068917", "gene_names_uniprotkb": "PEX16", "gene_names_refseq": "PEX16", "protein_names_uniprotkb": "Peroxisomal membrane protein PEX16; Peroxin-16; Peroxisomal biogenesis factor 16", "protein_names_refseq": "peroxin-16; peroxisomal biogenesis factor 16; peroxisomal membrane protein PEX16", "tax_id": 9913, "disease": "", "pathway": " (bta:510447); (R-BTA-9603798)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Required for peroxisome membrane biogenesis. May play a role in early stages of peroxisome assembly. Can recruit other peroxisomal proteins, such as PEX3 and PMP34, to de novo peroxisomes derived from the endoplasmic reticulum (ER). May function as receptor for PEX3 (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005777 peroxisome;GO:0005778 peroxisomal membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0007031 peroxisome organization;GO:0006625 protein targeting to peroxisome;GO:0016557 peroxisome membrane biogenesis;GO:0032581 ER-dependent peroxisome organization;GO:0045046 protein import into peroxisome membrane", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2KII7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q17QC5-1", "uniprot_id": "AP2S1_BOVIN", "mass": 17018.0, "length": 142, "protein_name": "AP-2 complex subunit sigma", "gene_name": "AP2S1", "organism": "Bovine", "refseq_name": "AP-2 complex subunit sigma", "refseq_ac": "NP_001069546", "gene_names_uniprotkb": "AP2S1", "gene_names_refseq": "AP2S1", "protein_names_uniprotkb": "AP-2 complex subunit sigma; Adaptor protein complex AP-2 subunit sigma; Adaptor-related protein complex 2 subunit sigma; Clathrin assembly protein 2 sigma small chain; Clathrin coat assembly protein AP17; Clathrin coat-associated protein AP17; Plasma membrane adaptor AP-2 17 kDa protein; Sigma2-adaptin", "protein_names_refseq": "AP-2 complex subunit sigma; adapter-related protein complex 2 sigma subunit; adapter-related protein complex 2 subunit sigma; adaptor protein complex AP-2 subunit sigma; adaptor related protein complex 2 sigma 1 subunit; adaptor-related protein complex 2 subunit sigma; clathrin assembly protein 2 sigma small chain; clathrin assembly protein 2 small chain; clathrin coat assembly protein AP17; clathrin coat-associated protein AP17; plasma membrane adaptor AP-2 17 kDa protein; sigma2-adaptin", "tax_id": 9913, "disease": "", "pathway": " (bta:536553); (R-BTA-177504); (R-BTA-2132295); (R-BTA-416993); (R-BTA-437239); (R-BTA-5099900); (R-BTA-5140745); (R-BTA-8856825); (R-BTA-8856828); (R-BTA-8866427); (R-BTA-8964038)", "pathway_count": 11, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein Transport via Transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but is itself unable to bind directly to membrane components. Clathrin-associated adaptor protein (AP) complexes which can bind directly to both the clathrin lattice and to the lipid and protein components of membranes are considered to be the major clathrin adaptors contributing the CCV formation. AP-2 also serves as a cargo receptor to selectively sort the membrane proteins involved in receptor-mediated endocytosis. AP-2 seems to play a role in the recycling of synaptic vesicle membranes from the presynaptic surface. AP-2 recognizes Y-X-X-[FILMV] (Y-X-X-Phi) and [ED]-X-X-X-L-[LI] endocytosis signal motifs within the cytosolic tails of transmembrane cargo molecules. AP-2 may also play a role in maintaining normal post-endocytic trafficking through the ARF6-regulated, non-clathrin pathway. The AP-2 alpha and AP-2 sigma subunits are thought to contribute to the recognition of the [ED]-X-X-X-L-[LI] motif. May also play a role in extracellular calcium homeostasis (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0035615 clathrin adaptor activity", "go_cellular_component": "GO:0030122 AP-2 adaptor complex;GO:0012505 endomembrane system;GO:0030117 membrane coat", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0016192 vesicle-mediated transport;GO:0072583 clathrin-dependent endocytosis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q17QC5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KID4-1", "uniprot_id": "DNAL1_BOVIN", "mass": 21536.0, "length": 190, "protein_name": "Dynein axonemal light chain 1", "gene_name": "ACOT6; DNAL1", "organism": "Bovine", "refseq_name": "dynein axonemal light chain 1", "refseq_ac": "NP_001039892", "gene_names_uniprotkb": "ACOT6; DNAL1; ACOT6", "gene_names_refseq": "DNAL1", "protein_names_uniprotkb": "Dynein axonemal light chain 1", "protein_names_refseq": "dynein axonemal light chain 1; dynein light chain 1, axonemal", "tax_id": 9913, "disease": "", "pathway": " (bta:511431); (bta:538164); (R-BTA-390247); (R-BTA-9033241)", "pathway_count": 4, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Part of the multisubunit axonemal ATPase complexes that generate the force for cilia motility and govern beat frequency (By similarity). Component of the outer arm dynein (ODA). May be involved in a mechanosensory feedback mechanism controlling ODA activity based on external conformational cues by tethering the outer arm dynein heavy chain (DNAH5) to the microtubule within the axoneme (By similarity). Important for ciliary function in the airways and for the function of the cilia that produce the nodal flow essential for the determination of the left-right asymmetry (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0043014 alpha-tubulin binding;GO:0045504 dynein heavy chain binding;GO:0047617 fatty acyl-CoA hydrolase activity;GO:0016790 thiolester hydrolase activity", "go_cellular_component": "GO:0005874 microtubule;GO:0005930 axoneme;GO:0030286 dynein complex;GO:0005777 peroxisome", "go_biological_process": "GO:0036158 outer dynein arm assembly;GO:0006631 fatty acid metabolic process;GO:0006637 acyl-CoA metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2KID4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KI41-1", "uniprot_id": "CYH2_BOVIN", "mass": 47492.0, "length": 410, "protein_name": "Cytohesin-2", "gene_name": "CYTH2; CYTH3", "organism": "Bovine", "refseq_name": "cytohesin-2", "refseq_ac": "NP_001070562", "gene_names_uniprotkb": "CYTH2; CYTH3; PSCD2", "gene_names_refseq": "CYTH2; PSCD2", "protein_names_uniprotkb": "Cytohesin-2; PH, SEC7 and coiled-coil domain-containing protein 2", "protein_names_refseq": "PH, SEC7 and coiled-coil domain-containing protein 2; cytohesin-2; pleckstrin homology, Sec7 and coiled-coil domains 2 (cytohesin-2)", "tax_id": 9913, "disease": "", "pathway": " (bta:768035); (R-BTA-6811438)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Acts as a guanine-nucleotide exchange factor (GEF). Promotes guanine-nucleotide exchange on ARF1, ARF3 and ARF6. Promotes the activation of ARF factors through replacement of GDP with GTP. The cell membrane form, in association with ARL4 proteins, recruits ARF6 to the plasma membrane (By similarity). Involved in neurite growth (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0070679 inositol 1,4,5 trisphosphate binding;GO:0008289 lipid binding;GO:0005085 guanyl-nucleotide exchange factor activity;GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0030426 growth cone;GO:0005829 cytosol;GO:0005912 adherens junction", "go_biological_process": "GO:0016192 vesicle-mediated transport;GO:0032012 regulation of ARF protein signal transduction;GO:0048193 Golgi vesicle transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2KI41-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KID9-1", "uniprot_id": "RT05_BOVIN", "mass": 47872.0, "length": 430, "protein_name": "Small ribosomal subunit protein uS5m", "gene_name": "MRPS5", "organism": "Bovine", "refseq_name": "small ribosomal subunit protein uS5m", "refseq_ac": "NP_001039588", "gene_names_uniprotkb": "MRPS5", "gene_names_refseq": "MRPS5", "protein_names_uniprotkb": "Small ribosomal subunit protein uS5m; 28S ribosomal protein S5, mitochondrial; MRP-S5; S5mt", "protein_names_refseq": "28S ribosomal protein S5, mitochondrial; MRP-S5; S5mt; small ribosomal subunit protein uS5m", "tax_id": 9913, "disease": "", "pathway": " (bta:512469); (R-BTA-5389840); (R-BTA-5419276); (R-BTA-9937383)", "pathway_count": 4, "publication_count": 2, "publication_id_list": "11344316;24799711", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "P82674", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding;GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005763 mitochondrial small ribosomal subunit;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0006412 translation;GO:0032543 mitochondrial translation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q2KID9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q148G8-1", "uniprot_id": "UQCC3_BOVIN", "mass": 9925.0, "length": 95, "protein_name": "Ubiquinol-cytochrome-c reductase complex assembly factor 3", "gene_name": "UQCC3", "organism": "Bovine", "refseq_name": "ubiquinol-cytochrome-c reductase complex assembly factor 3", "refseq_ac": "NP_001069182", "gene_names_uniprotkb": "UQCC3", "gene_names_refseq": "C29H11orf83; UQCC3", "protein_names_uniprotkb": "Ubiquinol-cytochrome-c reductase complex assembly factor 3", "protein_names_refseq": "UPF0723 protein C11orf83 homolog; ubiquinol-cytochrome-c reductase complex assembly factor 3", "tax_id": 9913, "disease": "", "pathway": " (bta:515452)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Required for the assembly of the ubiquinol-cytochrome c reductase complex (mitochondrial respiratory chain complex III or cytochrome b-c1 complex), mediating cytochrome b recruitment and probably stabilization within the complex. Thereby, plays an important role in ATP production by mitochondria. Cardiolipin-binding protein, it may also control the cardiolipin composition of mitochondria membranes and their morphology., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0070300 phosphatidic acid binding;GO:1901612 cardiolipin binding", "go_cellular_component": "GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0006754 ATP biosynthetic process;GO:0042407 cristae formation;GO:0034551 mitochondrial respiratory chain complex III assembly;GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q148G8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KIS2-1", "uniprot_id": "RM44_BOVIN", "mass": 37412.0, "length": 332, "protein_name": "Large ribosomal subunit protein mL44", "gene_name": "MRPL44", "organism": "Bovine", "refseq_name": "large ribosomal subunit protein mL44 precursor", "refseq_ac": "NP_001039786", "gene_names_uniprotkb": "MRPL44", "gene_names_refseq": "MRPL44", "protein_names_uniprotkb": "Large ribosomal subunit protein mL44; 39S ribosomal protein L44, mitochondrial; L44mt; MRP-L44", "protein_names_refseq": "39S ribosomal protein L44, mitochondrial; L44mt; MRP-L44; large ribosomal subunit protein mL44 precursor; large ribosomal subunit protein mL44", "tax_id": 9913, "disease": "", "pathway": " (bta:532389); (R-BTA-5389840); (R-BTA-5419276); (R-BTA-9937383)", "pathway_count": 4, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of the 39S subunit of mitochondrial ribosome. May have a function in the assembly/stability of nascent mitochondrial polypeptides exiting the ribosome., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003725 double-stranded RNA binding;GO:0004525 ribonuclease III activity", "go_cellular_component": "GO:0005762 mitochondrial large ribosomal subunit;GO:0005634 nucleus;GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane;GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0006396 RNA processing;GO:0006417 regulation of translation;GO:0070125 mitochondrial translational elongation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2KIS2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KIG0-1", "uniprot_id": "ETFD_BOVIN", "mass": 68612.0, "length": 617, "protein_name": "Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial", "gene_name": "ETFDH", "organism": "Bovine", "refseq_name": "electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial precursor", "refseq_ac": "NP_001070598", "gene_names_uniprotkb": "ETFDH", "gene_names_refseq": "ETFDH", "protein_names_uniprotkb": "Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial; 1.5.5.1; ETF dehydrogenase; ETF-QO; ETF-ubiquinone oxidoreductase; Electron-transferring-flavoprotein dehydrogenase", "protein_names_refseq": "ETF dehydrogenase; ETF-QO; ETF-ubiquinone oxidoreductase; electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial precursor; electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial; electron-transferring-flavoprotein dehydrogenase", "tax_id": 9913, "disease": "", "pathway": " (bta:768074)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Accepts electrons from ETF and reduces ubiquinone., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Links fatty acid beta-oxidation and amino acid catabolism to the respiratory chain by transferring electrons from the electron transfer flavoprotein (ETF) to ubiquinone., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.5.5.1", "go_molecular_function": "GO:0046872 metal ion binding;GO:0051539 4 iron, 4 sulfur cluster binding;GO:0004174 electron-transferring-flavoprotein dehydrogenase activity;GO:0048039 ubiquinone binding", "go_cellular_component": "GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0022900 electron transport chain;GO:0006979 response to oxidative stress;GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2KIG0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q1RMH4-1", "uniprot_id": "PRAF1_BOVIN", "mass": 20626.0, "length": 185, "protein_name": "Prenylated Rab acceptor protein 1", "gene_name": "RABAC1", "organism": "Bovine", "refseq_name": "prenylated Rab acceptor protein 1", "refseq_ac": "NP_001069043", "gene_names_uniprotkb": "RABAC1; PRAF1", "gene_names_refseq": "RABAC1", "protein_names_uniprotkb": "Prenylated Rab acceptor protein 1; PRA1 family protein 1", "protein_names_refseq": "PRA1 family protein 1; prenylated Rab acceptor protein 1", "tax_id": 9913, "disease": "", "pathway": " (bta:512653)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "General Rab protein regulator required for vesicle formation from the Golgi complex. May control vesicle docking and fusion by mediating the action of Rab GTPases to the SNARE complexes. In addition it inhibits the removal of Rab GTPases from the membrane by GDI1., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0042802 identical protein binding", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0005886 plasma membrane;GO:0008021 synaptic vesicle;GO:0016020 membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q1RMH4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q148F0-1", "uniprot_id": "URM1_BOVIN", "mass": 11283.0, "length": 101, "protein_name": "Ubiquitin-related modifier 1", "gene_name": "URM1", "organism": "Bovine", "refseq_name": "ubiquitin-related modifier 1", "refseq_ac": "NP_001069197", "gene_names_uniprotkb": "URM1", "gene_names_refseq": "URM1", "protein_names_uniprotkb": "Ubiquitin-related modifier 1", "protein_names_refseq": "ubiquitin-related modifier 1 homolog; ubiquitin-related modifier 1", "tax_id": 9913, "disease": "", "pathway": " (bta:515890)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by MOCS3. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins such as MOCS3, ATPBD3, CTU2, USP15 and CAS. The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates., [UniProtKB, HAMAP, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0000166 nucleotide binding;GO:0031386 protein tag activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0005737 cytoplasm", "go_biological_process": "GO:0034227 tRNA thio-modification;GO:0002098 tRNA wobble uridine modification;GO:0032447 protein urmylation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q148F0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KJJ0-1", "uniprot_id": "PRP6_BOVIN", "mass": 106678.0, "length": 941, "protein_name": "Pre-mRNA-processing factor 6", "gene_name": "PRPF6", "organism": "Bovine", "refseq_name": "pre-mRNA-processing factor 6", "refseq_ac": "NP_001039840", "gene_names_uniprotkb": "PRPF6", "gene_names_refseq": "PRPF6", "protein_names_uniprotkb": "Pre-mRNA-processing factor 6; PRP6 homolog; U5 snRNP-associated 102 kDa protein; U5-102 kDa protein", "protein_names_refseq": "PRP6 homolog; PRP6 pre-mRNA processing factor 6 homolog; U5 snRNP-associated 102 kDa protein; U5-102 kDa protein; pre-mRNA-processing factor 6", "tax_id": 9913, "disease": "", "pathway": " (bta:534228); (R-BTA-72163); (R-BTA-72165)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Involved in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex, one of the building blocks of the spliceosome. Enhances dihydrotestosterone-induced transactivation activity of AR, as well as dexamethasone-induced transactivation activity of NR3C1, but does not affect estrogen-induced transactivation., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0030674 protein-macromolecule adaptor activity;GO:0003723 RNA binding;GO:0042802 identical protein binding;GO:0043021 ribonucleoprotein complex binding", "go_cellular_component": "GO:0016607 nuclear speck;GO:0071013 catalytic step 2 spliceosome;GO:0046540 U4/U6 x U5 tri-snRNP complex;GO:0071005 U2-type precatalytic spliceosome;GO:0005634 nucleus", "go_biological_process": "GO:0000244 spliceosomal tri-snRNP complex assembly;GO:0000398 mRNA splicing, via spliceosome", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2KJJ0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q1LZ97-1", "uniprot_id": "GRP4_BOVIN", "mass": 74824.0, "length": 673, "protein_name": "RAS guanyl-releasing protein 4", "gene_name": "RASGRP4", "organism": "Bovine", "refseq_name": "RAS guanyl-releasing protein 4", "refseq_ac": "NP_001030456", "gene_names_uniprotkb": "RASGRP4", "gene_names_refseq": "RASGRP4", "protein_names_uniprotkb": "RAS guanyl-releasing protein 4", "protein_names_refseq": "RAS guanyl-releasing protein 4", "tax_id": 9913, "disease": "", "pathway": " (bta:529375); (R-BTA-5673001)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "Functions as a cation- and diacylglycerol (DAG)-regulated nucleotide exchange factor activating Ras through the exchange of bound GDP for GTP (By similarity). In neutrophils, participates in a phospholipase C-activating N-formyl peptide-activated GPCR (G protein-coupled receptor) signaling pathway by promoting Ras-mediated activation of PIK3CG/PI3Kgamma to promote neutrophil functional responses (By similarity). In CD117(+) dendritic cells and mast cells, participates in an lipopolysaccharide (LPS)-activated signaling pathway that stimulates the production of interferon-gamma and other pro-inflammatory cytokines by natural killer (NK) cells (By similarity). May function in mast cell differentiation (By similarity). Does not appear to be required for the development of B-cells, DC-cells, T-cells, or NK-cells (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q58D14", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0005509 calcium ion binding;GO:0005085 guanyl-nucleotide exchange factor activity;GO:0019992 diacylglycerol binding", "go_cellular_component": "GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0009898 cytoplasmic side of plasma membrane", "go_biological_process": "GO:0002717 positive regulation of natural killer cell mediated immunity;GO:0030154 cell differentiation;GO:0007265 Ras protein signal transduction;GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway;GO:0140367 antibacterial innate immune response", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q1LZ97-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KHV4-1", "uniprot_id": "PARL_BOVIN", "mass": 42301.0, "length": 377, "protein_name": "Presenilin-associated rhomboid-like protein, mitochondrial", "gene_name": "PARL", "organism": "Bovine", "refseq_name": "presenilin-associated rhomboid-like protein, mitochondrial precursor", "refseq_ac": "NP_001015596", "gene_names_uniprotkb": "PARL; PSARL", "gene_names_refseq": "PARL; PSARL", "protein_names_uniprotkb": "Presenilin-associated rhomboid-like protein, mitochondrial; 3.4.21.105; Mitochondrial intramembrane cleaving protease PARL", "protein_names_refseq": "mitochondrial intramembrane cleaving protease PARL; presenilin associated, rhomboid-like preproprotein; presenilin-associated rhomboid-like protein, mitochondrial precursor; presenilin-associated rhomboid-like protein, mitochondrial; presenilins-associated rhomboid-like protein, mitochondrial", "tax_id": 9913, "disease": "", "pathway": " (bta:514191); (R-BTA-8949664)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "Required for the control of apoptosis during postnatal growth. Essential for proteolytic processing of an antiapoptotic form of OPA1 which prevents the release of mitochondrial cytochrome c in response to intrinsic apoptotic signals (By similarity). Required for the maturation of PINK1 into its 52kDa mature form after its cleavage by mitochondrial-processing peptidase (MPP). Promotes cleavage of serine/threonine-protein phosphatase PGAM5 in damaged mitochondria in response to loss of mitochondrial membrane potential. Mediates differential cleavage of PINK1 and PGAM5 depending on the health status of mitochondria, disassociating from PINK1 and associating with PGAM5 in response to mitochondrial membrane potential loss. Required for processing of CLPB into a form with higher protein disaggregase activity by removing an autoinhibitory N-terminal peptide. Promotes processing of DIABLO/SMAC in the mitochondrion which is required for DIABLO apoptotic activity (By similarity). Mediates STARD7 processing which regulates STARD7 location between mitochodria and cytosol. Also required for cleavage of TTC19. Promotes changes in mitochondria morphology regulated by phosphorylation of P-beta domain (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A1L5A2;Q0V8C8;Q5EA93", "ec_number_list": "2.7.7.49;3.4.21.105", "go_molecular_function": "GO:0004252 serine-type endopeptidase activity;GO:0003964 RNA-directed DNA polymerase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0016485 protein processing;GO:0010821 regulation of mitochondrion organization;GO:0030162 regulation of proteolysis;GO:2000377 regulation of reactive oxygen species metabolic process;GO:0008053 mitochondrial fusion", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q2KHV4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KIT5-1", "uniprot_id": "CREL2_BOVIN", "mass": 38230.0, "length": 351, "protein_name": "Protein disulfide isomerase CRELD2", "gene_name": "CRELD2", "organism": "Bovine", "refseq_name": "protein disulfide isomerase CRELD2 precursor", "refseq_ac": "NP_001039656", "gene_names_uniprotkb": "CRELD2", "gene_names_refseq": "CRELD2", "protein_names_uniprotkb": "Protein disulfide isomerase CRELD2; 5.3.4.1; Cysteine-rich with EGF-like domain protein 2", "protein_names_refseq": "cysteine-rich with EGF-like domain protein 2; protein disulfide isomerase CRELD2 precursor; protein disulfide isomerase CRELD2", "tax_id": 9913, "disease": "", "pathway": " (bta:515222)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Protein disulfide isomerase (By similarity). Might play a role in the unfolded protein response (By similarity). May regulate transport of alpha4-beta2 neuronal acetylcholine receptor (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005509 calcium ion binding;GO:0003756 protein disulfide isomerase activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005783 endoplasmic reticulum;GO:0031012 extracellular matrix;GO:0005794 Golgi apparatus;GO:0016020 membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2KIT5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9TTJ5-1", "uniprot_id": "RGN_BOVIN", "mass": 33308.0, "length": 299, "protein_name": "Regucalcin", "gene_name": "RGN", "organism": "Bovine", "refseq_name": "regucalcin", "refseq_ac": "NP_776382", "gene_names_uniprotkb": "RGN; SMP30", "gene_names_refseq": "GNL; RGN", "protein_names_uniprotkb": "Regucalcin; 3.1.1.17; GNL; Gluconolactonase; RC; SMP-30; Senescence marker protein 30", "protein_names_refseq": "RC; SMP-30; gluconolactonase; regucalcin (senescence marker protein-30); regucalcin; senescence marker protein 30", "tax_id": 9913, "disease": "", "pathway": " (bta:280910)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "10891565;25415588", "class_list": "", "function": "Estrogen administration down-regulated RGN gene expression in the accessory sex glands of veal calves and beef cattle, while androgen treatment reduced RGN gene expression only in the testis. Publication Status: Online-Only, [RefSeq, PubMed]; Gluconolactonase with low activity towards other sugar lactones, including gulonolactone and galactonolactone. Catalyzes a key step in ascorbic acid (vitamin C) biosynthesis. Can also hydrolyze diisopropyl phosphorofluoridate and phenylacetate (in vitro). Calcium-binding protein. Modulates Ca(2+) signaling, and Ca(2+)-dependent cellular processes and enzyme activities (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q3ZBB2", "ec_number_list": "3.1.1.17", "go_molecular_function": "GO:0004341 gluconolactonase activity;GO:0008270 zinc ion binding;GO:0005509 calcium ion binding;GO:0030234 enzyme regulator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006874 intracellular calcium ion homeostasis;GO:0032781 positive regulation of ATP-dependent activity;GO:0019853 L-ascorbic acid biosynthetic process;GO:0050848 regulation of calcium-mediated signaling", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q9TTJ5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KIS1-1", "uniprot_id": "RENBP_BOVIN", "mass": 48151.0, "length": 422, "protein_name": "N-acylglucosamine 2-epimerase", "gene_name": "RENBP", "organism": "Bovine", "refseq_name": "N-acylglucosamine 2-epimerase", "refseq_ac": "NP_001039688", "gene_names_uniprotkb": "RENBP", "gene_names_refseq": "AGE; RENBP; RnBP", "protein_names_uniprotkb": "N-acylglucosamine 2-epimerase; 5.1.3.8; AGE; GlcNAc 2-epimerase; N-acetyl-D-glucosamine 2-epimerase; Renin-binding protein; RnBP", "protein_names_refseq": "N-acetyl-D-glucosamine 2-epimerase; N-acylglucosamine 2-epimerase; glcNAc 2-epimerase", "tax_id": 9913, "disease": "", "pathway": " (bta:516214); (R-BTA-446210)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalyzes the interconversion of N-acetylglucosamine to N-acetylmannosamine. Involved in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "5.1.3.8", "go_molecular_function": "GO:0050121 N-acylglucosamine 2-epimerase activity;GO:0030414 peptidase inhibitor activity;GO:0042802 identical protein binding", "go_cellular_component": "", "go_biological_process": "GO:0005975 carbohydrate metabolic process;GO:0019262 N-acetylneuraminate catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2KIS1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q95323-1", "uniprot_id": "CAH4_BOVIN", "mass": 35151.0, "length": 312, "protein_name": "Carbonic anhydrase 4", "gene_name": "CA4", "organism": "Bovine", "refseq_name": "carbonic anhydrase 4 precursor", "refseq_ac": "NP_776322", "gene_names_uniprotkb": "CA4", "gene_names_refseq": "CA4", "protein_names_uniprotkb": "Carbonic anhydrase 4; 4.2.1.1; CA-IV; Carbonate dehydratase IV; Carbonic anhydrase IV", "protein_names_refseq": "CA-IV; carbonate dehydratase IV; carbonic anhydrase 4 precursor; carbonic anhydrase IV", "tax_id": 9913, "disease": "", "pathway": " (bta:280741); (R-BTA-1237044); (R-BTA-1247673); (R-BTA-1475029)", "pathway_count": 4, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalyzes the reversible hydration of carbon dioxide into bicarbonate and protons and thus is essential to maintaining intracellular and extracellular pH. May stimulate the sodium/bicarbonate transporter activity of SLC4A4 that acts in pH homeostasis. It is essential for acid overload removal from the retina and retina epithelium, and acid release in the choriocapillaris in the choroid., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 4, "predicted_n_glycosites": 4, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "A5PKL8", "ec_number_list": "4.2.1.1;4.2.1.69", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0004089 carbonate dehydratase activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0098552 side of membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q95323-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2HJ52-1", "uniprot_id": "TBP_BOVIN", "mass": 35219.0, "length": 319, "protein_name": "TATA-box-binding protein", "gene_name": "TBP", "organism": "Bovine", "refseq_name": "TATA-box-binding protein", "refseq_ac": "NP_001069210", "gene_names_uniprotkb": "TBP", "gene_names_refseq": "TBP", "protein_names_uniprotkb": "TATA-box-binding protein; TATA sequence-binding protein; TATA-binding factor; TATA-box factor; Transcription initiation factor TFIID TBP subunit", "protein_names_refseq": "TATA sequence-binding protein; TATA-binding factor; TATA-box factor; TATA-box-binding protein; transcription initiation factor TFIID TBP subunit", "tax_id": 9913, "disease": "", "pathway": " (bta:516578)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II. Component of a BRF2-containing transcription factor complex that regulates transcription mediated by RNA polymerase III. Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (pre-initiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1 with the rDNA promoter. SL1 is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0001164 RNA polymerase I core promoter sequence-specific DNA binding;GO:0016251 RNA polymerase II general transcription initiation factor activity;GO:0000995 RNA polymerase III general transcription initiation factor activity;GO:0003677 DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005669 transcription factor TFIID complex", "go_biological_process": "GO:0006366 transcription by RNA polymerase II;GO:0006383 transcription by RNA polymerase III;GO:0006352 DNA-templated transcription initiation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2HJ52-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q29RL9-1", "uniprot_id": "TCEA1_BOVIN", "mass": 33891.0, "length": 301, "protein_name": "Transcription elongation factor A protein 1", "gene_name": "TCEA1", "organism": "Bovine", "refseq_name": "transcription elongation factor A protein 1", "refseq_ac": "NP_001039390", "gene_names_uniprotkb": "TCEA1", "gene_names_refseq": "TCEA1", "protein_names_uniprotkb": "Transcription elongation factor A protein 1; Transcription elongation factor S-II protein 1", "protein_names_refseq": "transcription elongation factor A (SII), 1; transcription elongation factor A protein 1; transcription elongation factor S-II protein 1", "tax_id": 9913, "disease": "", "pathway": " (bta:505722); (R-BTA-674695); (R-BTA-6781823); (R-BTA-6782135); (R-BTA-6782210); (R-BTA-6796648); (R-BTA-75955)", "pathway_count": 7, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0003711 transcription elongation factor activity;GO:0003676 nucleic acid binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005669 transcription factor TFIID complex", "go_biological_process": "GO:0006368 transcription elongation by RNA polymerase II;GO:0006351 DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q29RL9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q29RI9-1", "uniprot_id": "MAT2B_BOVIN", "mass": 37768.0, "length": 334, "protein_name": "Methionine adenosyltransferase 2 subunit beta", "gene_name": "MAT2B", "organism": "Bovine", "refseq_name": "methionine adenosyltransferase 2 subunit beta", "refseq_ac": "NP_001039991", "gene_names_uniprotkb": "MAT2B", "gene_names_refseq": "MAT2B", "protein_names_uniprotkb": "Methionine adenosyltransferase 2 subunit beta; MAT II beta; Methionine adenosyltransferase II beta", "protein_names_refseq": "MAT II beta; methionine adenosyltransferase 2 beta subunit; methionine adenosyltransferase 2 subunit beta; methionine adenosyltransferase II, beta", "tax_id": 9913, "disease": "", "pathway": " (bta:614177); (R-BTA-5689880)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine. Can bind NADP (in vitro)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0030234 enzyme regulator activity", "go_cellular_component": "GO:0048269 methionine adenosyltransferase complex", "go_biological_process": "GO:0006730 one-carbon metabolic process;GO:0006556 S-adenosylmethionine biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q29RI9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q17QF9-1", "uniprot_id": "CBLN3_BOVIN", "mass": 21747.0, "length": 205, "protein_name": "Cerebellin-3", "gene_name": "CBLN3", "organism": "Bovine", "refseq_name": "cerebellin-3 precursor", "refseq_ac": "NP_001073071", "gene_names_uniprotkb": "CBLN3", "gene_names_refseq": "CBLN3", "protein_names_uniprotkb": "Cerebellin-3", "protein_names_refseq": "cerebellin-3 precursor; cerebellin-3", "tax_id": 9913, "disease": "", "pathway": " (bta:529166)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "May be involved in synaptic functions in the CNS., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005615 extracellular space;GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0045202 synapse;GO:0043083 synaptic cleft", "go_biological_process": "GO:0099558 maintenance of synapse structure;GO:0099550 trans-synaptic signaling, modulating synaptic transmission", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q17QF9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KHZ9-1", "uniprot_id": "GCDH_BOVIN", "mass": 48472.0, "length": 438, "protein_name": "Glutaryl-CoA dehydrogenase, mitochondrial", "gene_name": "GCDH", "organism": "Bovine", "refseq_name": "glutaryl-CoA dehydrogenase, mitochondrial precursor", "refseq_ac": "NP_001039404", "gene_names_uniprotkb": "GCDH; SYCE2", "gene_names_refseq": "GCDH", "protein_names_uniprotkb": "Glutaryl-CoA dehydrogenase, mitochondrial; 1.3.8.6; GCD", "protein_names_refseq": "GCD; glutaryl-CoA dehydrogenase, mitochondrial precursor; glutaryl-CoA dehydrogenase, mitochondrial; glutaryl-Coenzyme A dehydrogenase", "tax_id": 9913, "disease": "", "pathway": " (bta:100141142); (bta:506310); (R-BTA-71064)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway of L-lysine, L-hydroxylysine, and L-tryptophan metabolism. It uses electron transfer flavoprotein as its electron acceptor (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.3.8.6", "go_molecular_function": "GO:0004361 glutaryl-CoA dehydrogenase activity;GO:0050660 flavin adenine dinucleotide binding;GO:0000062 fatty-acyl-CoA binding", "go_cellular_component": "GO:0005759 mitochondrial matrix;GO:0000801 central element;GO:0005654 nucleoplasm", "go_biological_process": "GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase;GO:0046949 fatty-acyl-CoA biosynthetic process;GO:0006568 L-tryptophan metabolic process;GO:0007130 synaptonemal complex assembly", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2KHZ9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q1JQD2-1", "uniprot_id": "GRWD1_BOVIN", "mass": 49463.0, "length": 446, "protein_name": "Glutamate-rich WD repeat-containing protein 1", "gene_name": "GRWD1", "organism": "Bovine", "refseq_name": "glutamate-rich WD repeat-containing protein 1", "refseq_ac": "NP_001069707", "gene_names_uniprotkb": "GRWD1", "gene_names_refseq": "GRWD1", "protein_names_uniprotkb": "Glutamate-rich WD repeat-containing protein 1", "protein_names_refseq": "glutamate-rich WD repeat-containing protein 1", "tax_id": 9913, "disease": "", "pathway": " (bta:540739)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Histone binding protein that regulates chromatin dynamics and minichromosome maintenance (MCM) loading at replication origins, possibly by promoting chromatin openness., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003688 DNA replication origin binding;GO:0003682 chromatin binding;GO:0042393 histone binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005730 nucleolus;GO:0005694 chromosome;GO:0005654 nucleoplasm;GO:0032991 protein-containing complex", "go_biological_process": "GO:0006260 DNA replication;GO:0042254 ribosome biogenesis;GO:0006334 nucleosome assembly;GO:0006337 nucleosome disassembly", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q1JQD2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KIG8-1", "uniprot_id": "T4S5_BOVIN", "mass": 20652.0, "length": 196, "protein_name": "Transmembrane 4 L6 family member 5", "gene_name": "TM4SF5", "organism": "Bovine", "refseq_name": "transmembrane 4 L6 family member 5", "refseq_ac": "NP_001039567", "gene_names_uniprotkb": "TM4SF5", "gene_names_refseq": "TM4SF5", "protein_names_uniprotkb": "Transmembrane 4 L6 family member 5", "protein_names_refseq": "transmembrane 4 L6 family member 5", "tax_id": 9913, "disease": "", "pathway": " (bta:511869)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Acts as a lysosomal membrane arginine sensor (By similarity). Forms a complex with MTOR and SLC38A9 on lysosomal membranes in an arginine-regulated manner, leading to arginine efflux which enables the activation of mTORC1 which subsequently leads to RPS6KB1 and EIF4EBP1 phosphorylations (By similarity). Facilitates cell cycle G1/S phase progression and the translocation of the CDK4-CCND1 complex into the nucleus (By similarity). CDKN1B and RHOA/ROCK signaling activity are involved in TM4SF5-mediated acceleration of G1/S phase progression (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0034618 arginine binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane;GO:0005765 lysosomal membrane", "go_biological_process": "GO:2000045 regulation of G1/S transition of mitotic cell cycle", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2KIG8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q29RS4-1", "uniprot_id": "IN80E_BOVIN", "mass": 26384.0, "length": 244, "protein_name": "INO80 complex subunit E", "gene_name": "INO80E", "organism": "Bovine", "refseq_name": "INO80 complex subunit E", "refseq_ac": "NP_001040009", "gene_names_uniprotkb": "INO80E; CCDC95", "gene_names_refseq": "CCDC95; INO80E", "protein_names_uniprotkb": "INO80 complex subunit E; Coiled-coil domain-containing protein 95", "protein_names_refseq": "INO80 complex subunit E; coiled-coil domain containing 95; coiled-coil domain-containing protein 95", "tax_id": 9913, "disease": "", "pathway": " (bta:614852); (R-BTA-5689603); (R-BTA-5696394)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Putative regulatory component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0031011 Ino80 complex;GO:0005654 nucleoplasm;GO:0005730 nucleolus", "go_biological_process": "GO:0006281 DNA repair;GO:0006310 DNA recombination;GO:0006338 chromatin remodeling;GO:0006351 DNA-templated transcription;GO:0060382 regulation of DNA strand elongation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q29RS4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9TU73-1", "uniprot_id": "IL18_BOVIN", "mass": 22347.0, "length": 193, "protein_name": "Interleukin-18", "gene_name": "IL18", "organism": "Bovine", "refseq_name": "interleukin-18", "refseq_ac": "NP_776516", "gene_names_uniprotkb": "IL18; IGIF", "gene_names_refseq": "IL18", "protein_names_uniprotkb": "Interleukin-18; IFN-gamma-inducing factor; IL-1 gamma; IL-18; Interferon gamma-inducing factor; Interleukin-1 gamma", "protein_names_refseq": "IFN-gamma-inducing factor; IL-1 gamma; IL-18; interferon gamma-inducing factor; interleukin 18 (interferon-gamma-inducing factor); interleukin-1 gamma; interleukin-18", "tax_id": 9913, "disease": "", "pathway": " (bta:281249); (R-BTA-448706); (R-BTA-5620971); (R-BTA-9012546); (R-BTA-9960519); (R-BTA-9960525)", "pathway_count": 6, "publication_count": 3, "publication_id_list": "10547157;18761716;33459528", "class_list": "", "function": "Effects of IL-18 on the proliferation and steroidogenesis of bovine theca cells: Possible roles in the pathogenesis of polycystic ovary syndrome., [RefSeq, PubMed]; Pro-inflammatory cytokine primarily involved in epithelial barrier repair, polarized T-helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells and natural killer (NK) cells. Involved in transduction of inflammation downstream of pyroptosis: its mature form is specifically released in the extracellular milieu by passing through the gasdermin-D (GSDMD) pore., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; These results suggest that BAPC-1 is a stem/progenitor cell line and modulates the immuno-endocrine function of the anterior pituitary cells through its production of interleukin-18 and the IL-18 receptor., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A9QWR6;Q3SZF6", "ec_number_list": "", "go_molecular_function": "GO:0045515 interleukin-18 receptor binding;GO:0005125 cytokine activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005829 cytosol", "go_biological_process": "GO:0006954 inflammatory response;GO:0006955 immune response;GO:0050830 defense response to Gram-positive bacterium;GO:0061436 establishment of skin barrier;GO:0071222 cellular response to lipopolysaccharide", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9TU73-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KIK0-1", "uniprot_id": "SGT1_BOVIN", "mass": 38074.0, "length": 338, "protein_name": "Protein SGT1 homolog", "gene_name": "SUGT1", "organism": "Bovine", "refseq_name": "protein SGT1 homolog", "refseq_ac": "NP_001039668", "gene_names_uniprotkb": "SUGT1", "gene_names_refseq": "SUGT1", "protein_names_uniprotkb": "Protein SGT1 homolog; Suppressor of G2 allele of SKP1 homolog", "protein_names_refseq": "SGT1, suppressor of G2 allele of SKP1; protein SGT1 homolog; suppressor of G2 allele of SKP1 homolog", "tax_id": 9913, "disease": "", "pathway": " (bta:515509); (R-BTA-844456)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "May play a role in ubiquitination and subsequent proteasomal degradation of target proteins., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0051087 protein-folding chaperone binding;GO:0106222 lncRNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0000776 kinetochore", "go_biological_process": "GO:0051382 kinetochore assembly", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2KIK0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q148I1-1", "uniprot_id": "PAAF1_BOVIN", "mass": 42194.0, "length": 392, "protein_name": "Proteasomal ATPase-associated factor 1", "gene_name": "PAAF1", "organism": "Bovine", "refseq_name": "proteasomal ATPase-associated factor 1", "refseq_ac": "NP_001069458", "gene_names_uniprotkb": "PAAF1; WDR71", "gene_names_refseq": "PAAF1; WDR71", "protein_names_uniprotkb": "Proteasomal ATPase-associated factor 1; WD repeat-containing protein 71", "protein_names_refseq": "WD repeat-containing protein 71; proteasomal ATPase-associated factor 1", "tax_id": 9913, "disease": "", "pathway": " (bta:533348)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Inhibits proteasome 26S assembly and activity by impairing the association of the 19S regulatory complex with the 20S core. Protects SUPT6H from proteasomal degradation (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0030621 U4 snRNA binding;GO:0017070 U6 snRNA binding", "go_cellular_component": "GO:0005829 cytosol;GO:0000502 proteasome complex;GO:0046540 U4/U6 x U5 tri-snRNP complex", "go_biological_process": "GO:0000398 mRNA splicing, via spliceosome", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q148I1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KJF1-1", "uniprot_id": "A1BG_BOVIN", "mass": 53554.0, "length": 503, "protein_name": "Alpha-1B-glycoprotein", "gene_name": "A1BG", "organism": "Bovine", "refseq_name": "alpha-1B-glycoprotein precursor", "refseq_ac": "NP_001039708", "gene_names_uniprotkb": "A1BG", "gene_names_refseq": "A1BG", "protein_names_uniprotkb": "Alpha-1B-glycoprotein; Alpha-1-B glycoprotein", "protein_names_refseq": "alpha-1B-glycoprotein precursor; alpha-1B-glycoprotein", "tax_id": 9913, "disease": "", "pathway": " (bta:518955); (R-BTA-114608); (R-BTA-6798695)", "pathway_count": 3, "publication_count": 2, "publication_id_list": "20116414;26495903", "class_list": "", "function": "", "predicted_glycosites": 5, "predicted_n_glycosites": 3, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004888 transmembrane signaling receptor activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0005886 plasma membrane", "go_biological_process": "GO:0060396 growth hormone receptor signaling pathway;GO:0007166 cell surface receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q2KJF1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KIE4-1", "uniprot_id": "MCTS1_BOVIN", "mass": 20555.0, "length": 181, "protein_name": "Malignant T-cell-amplified sequence 1", "gene_name": "MCTS1", "organism": "Bovine", "refseq_name": "malignant T-cell-amplified sequence 1", "refseq_ac": "NP_001039468", "gene_names_uniprotkb": "MCTS1", "gene_names_refseq": "MCTS1", "protein_names_uniprotkb": "Malignant T-cell-amplified sequence 1; MCT-1", "protein_names_refseq": "MCT-1; malignant T-cell-amplified sequence 1", "tax_id": 9913, "disease": "", "pathway": " (bta:508412)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Translation regulator forming a complex with DENR to promote translation reinitiation. Translation reinitiation is the process where the small ribosomal subunit remains attached to the mRNA following termination of translation of a regulatory upstream ORF (uORF), and resume scanning on the same mRNA molecule to initiate translation of a downstream ORF, usually the main ORF (mORF). The MCTS1/DENR complex is pivotal to two linked mechanisms essential for translation reinitiation. Firstly, the dissociation of deacylated tRNAs from post-termination 40S ribosomal complexes during ribosome recycling. Secondly, the recruitment in an EIF2-independent manner of aminoacylated initiator tRNA to P site of 40S ribosomes for a new round of translation. This regulatory mechanism governs the translation of more than 150 genes which translation reinitiation is MCTS1/DENR complex-dependent. Consequently, modulates various unrelated biological processes including cell cycle regulation and DNA damage signaling and repair. Notably, it positively regulates interferon gamma immunity to mycobacteria by enhancing the translation of JAK2., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0043024 ribosomal small subunit binding;GO:0003743 translation initiation factor activity;GO:0000339 RNA cap binding;GO:0003723 RNA binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0002188 translation reinitiation;GO:0032790 ribosome disassembly;GO:0006351 DNA-templated transcription;GO:0006974 DNA damage response;GO:0001731 formation of translation preinitiation complex", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2KIE4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q148H6-1", "uniprot_id": "K1C28_BOVIN", "mass": 50775.0, "length": 464, "protein_name": "Keratin, type I cytoskeletal 28", "gene_name": "KRT28", "organism": "Bovine", "refseq_name": "keratin, type I cytoskeletal 28", "refseq_ac": "NP_001073844", "gene_names_uniprotkb": "KRT28", "gene_names_refseq": "KRT10; KRT28", "protein_names_uniprotkb": "Keratin, type I cytoskeletal 28; CK-28; Cytokeratin-28; K28; Keratin-28; Type I inner root sheath-specific keratin-K25irs4", "protein_names_refseq": "CK-28; K28; cytokeratin-28; keratin 10 (epidermolytic hyperkeratosis; keratin, type I cytoskeletal 28; keratosis palmaris et plantaris); type I inner root sheath-specific keratin-K25irs4", "tax_id": 9913, "disease": "", "pathway": " (bta:788909); (R-BTA-6805567); (R-BTA-6809371)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Essential for the proper assembly of types I and II keratin protein complexes and the formation of keratin intermediate filaments in the inner root sheath (irs)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0030280 structural constituent of skin epidermis;GO:0005198 structural molecule activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005856 cytoskeleton;GO:0045095 keratin filament;GO:0005882 intermediate filament", "go_biological_process": "GO:0030855 epithelial cell differentiation;GO:0045109 intermediate filament organization;GO:0031069 hair follicle morphogenesis;GO:0002009 morphogenesis of an epithelium", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q148H6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q17QN6-1", "uniprot_id": "EM55_BOVIN", "mass": 52184.0, "length": 466, "protein_name": "55 kDa erythrocyte membrane protein", "gene_name": "MPP1", "organism": "Bovine", "refseq_name": "55 kDa erythrocyte membrane protein", "refseq_ac": "NP_001068952", "gene_names_uniprotkb": "MPP1; EMP55", "gene_names_refseq": "MPP1", "protein_names_uniprotkb": "55 kDa erythrocyte membrane protein; Membrane protein, palmitoylated 1; p55", "protein_names_refseq": "55 kDa erythrocyte membrane protein; membrane palmitoylated protein 1; membrane protein, palmitoylated 1, 55kDa; p55", "tax_id": 9913, "disease": "", "pathway": " (bta:510998)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "17584769", "class_list": "", "function": "Essential regulator of neutrophil polarity. Regulates neutrophil polarization by regulating AKT1 phosphorylation through a mechanism that is independent of PIK3CG activity., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005102 signaling receptor binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005911 cell-cell junction;GO:0032420 stereocilium;GO:0005856 cytoskeleton;GO:0030863 cortical cytoskeleton", "go_biological_process": "GO:0090022 regulation of neutrophil chemotaxis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q17QN6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q17R10-1", "uniprot_id": "AF1L2_BOVIN", "mass": 90789.0, "length": 817, "protein_name": "Actin filament-associated protein 1-like 2", "gene_name": "AFAP1L2", "organism": "Bovine", "refseq_name": "actin filament-associated protein 1-like 2", "refseq_ac": "NP_001069843", "gene_names_uniprotkb": "AFAP1L2", "gene_names_refseq": "AFAP1L2", "protein_names_uniprotkb": "Actin filament-associated protein 1-like 2; AFAP1-like protein 2", "protein_names_refseq": "AFAP1-like protein 2; actin filament-associated protein 1-like 2", "tax_id": 9913, "disease": "", "pathway": " (bta:615436)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "May play a role in a signaling cascade by enhancing the kinase activity of SRC. Contributes to SRC-regulated transcription activation (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 4, "predicted_n_glycosites": 0, "predicted_o_glycosites": 4, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0030296 protein tyrosine kinase activator activity;GO:0017124 SH3 domain binding;GO:0042169 SH2 domain binding", "go_cellular_component": "GO:0005829 cytosol;GO:0005737 cytoplasm", "go_biological_process": "GO:0006954 inflammatory response;GO:0007346 regulation of mitotic cell cycle;GO:0045893 positive regulation of DNA-templated transcription;GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway;GO:0032675 regulation of interleukin-6 production", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q17R10-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KJ11-1", "uniprot_id": "NKG7_BOVIN", "mass": 17758.0, "length": 165, "protein_name": "Protein NKG7", "gene_name": "NKG7", "organism": "Bovine", "refseq_name": "protein NKG7 isoform X1", "refseq_ac": "XP_005219600", "gene_names_uniprotkb": "NKG7", "gene_names_refseq": "NKG7", "protein_names_uniprotkb": "Protein NKG7; Natural killer cell protein 7", "protein_names_refseq": "protein NKG7 isoform X1", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Regulates cytotoxic granule exocytosis in effector lymphocytes, thus acting as a critical mediator of inflammation in a broad range of infectious and non-infectious diseases (By similarity). Essential for cytotoxic degranulation of natural killer (NK) cells and CD8(+) T-cells and for the activation of CD4(+) T-cells following infection (By similarity). Plays a critical role in CD8(+) T-cell and NK cell-mediated cytolysis of target cells and contributes to the cytolytic activity via the perforin/granzyme pathway by enhancing exocytosis of LAMP1-carrying lytic granules (By similarity). Contributes to NK cell-mediated control of cancer metastasis (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane;GO:0044194 cytolytic granule;GO:0101004 cytolytic granule membrane", "go_biological_process": "GO:0035710 CD4-positive, alpha-beta T cell activation;GO:0006954 inflammatory response;GO:0050729 positive regulation of inflammatory response;GO:0031640 killing of cells of another organism;GO:0042832 defense response to protozoan", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2KJ11-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KIZ3-1", "uniprot_id": "MCEE_BOVIN", "mass": 18514.0, "length": 175, "protein_name": "Methylmalonyl-CoA epimerase, mitochondrial", "gene_name": "MCEE", "organism": "Bovine", "refseq_name": "methylmalonyl-CoA epimerase, mitochondrial precursor", "refseq_ac": "NP_001039460", "gene_names_uniprotkb": "MCEE", "gene_names_refseq": "MCEE", "protein_names_uniprotkb": "Methylmalonyl-CoA epimerase, mitochondrial; 5.1.99.1; DL-methylmalonyl-CoA racemase", "protein_names_refseq": "DL-methylmalonyl-CoA racemase; methylmalonyl-CoA epimerase, mitochondrial precursor; methylmalonyl-CoA epimerase, mitochondrial", "tax_id": 9913, "disease": "", "pathway": " (bta:508170); (R-BTA-71032)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Methylmalonyl-CoA epimerase involved in propionyl-CoA metabolism., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "5.1.99.1", "go_molecular_function": "GO:0046872 metal ion binding;GO:0004493 methylmalonyl-CoA epimerase activity", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0046491 L-methylmalonyl-CoA metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2KIZ3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q1LZH5-1", "uniprot_id": "CREM_BOVIN", "mass": 38694.0, "length": 360, "protein_name": "cAMP-responsive element modulator", "gene_name": "CREM", "organism": "Bovine", "refseq_name": "cAMP-responsive element modulator", "refseq_ac": "NP_001029882", "gene_names_uniprotkb": "CREM", "gene_names_refseq": "CREM", "protein_names_uniprotkb": "cAMP-responsive element modulator", "protein_names_refseq": "cAMP-responsive element modulator", "tax_id": 9913, "disease": "", "pathway": " (bta:540605)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "24612697", "class_list": "", "function": "Results are consistent with the suggestions that cAMP responsive element modulator variants are involved in spermiogenesis in the testes of Japanese Black bulls, [RefSeq, PubMed]; Transcriptional regulator that binds the cAMP response element (CRE), a sequence present in many viral and cellular promoters. Isoforms are either transcriptional activators or repressors. Isoform 1 and isoform 2 are transcriptional activators. Plays a role in spermatogenesis and is involved in spermatid maturation (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q3SZW5", "ec_number_list": "", "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677 DNA binding;GO:0003700 DNA-binding transcription factor activity;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding", "go_cellular_component": "GO:1990589 ATF4-CREB1 transcription factor complex;GO:0005634 nucleus;GO:0005654 nucleoplasm", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0141156 cAMP/PKA signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q1LZH5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q0VCU8-1", "uniprot_id": "EIF3J_BOVIN", "mass": 28951.0, "length": 256, "protein_name": "Eukaryotic translation initiation factor 3 subunit J", "gene_name": "EIF3J", "organism": "Bovine", "refseq_name": "eukaryotic translation initiation factor 3 subunit J", "refseq_ac": "NP_001069611", "gene_names_uniprotkb": "EIF3J; EIF3S1", "gene_names_refseq": "EIF3J", "protein_names_uniprotkb": "Eukaryotic translation initiation factor 3 subunit J; Eukaryotic translation initiation factor 3 subunit 1; eIF-3-alpha; eIF3 p35; eIF3j", "protein_names_refseq": "eIF-3-alpha; eIF3 p35; eukaryotic translation initiation factor 3 subunit 1; eukaryotic translation initiation factor 3 subunit J", "tax_id": 9913, "disease": "", "pathway": " (bta:539052); (R-BTA-156827); (R-BTA-72649); (R-BTA-72689); (R-BTA-72695); (R-BTA-72702)", "pathway_count": 6, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression. This subunit binds directly within the mRNA entry channel of the 40S ribosome to the aminoacyl (A) site. It may regulate the interaction between the 43S PIC and mRNA., [UniProtKB, HAMAP, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A6QPP4", "ec_number_list": "", "go_molecular_function": "GO:0042802 identical protein binding;GO:0003743 translation initiation factor activity", "go_cellular_component": "GO:0016282 eukaryotic 43S preinitiation complex;GO:0033290 eukaryotic 48S preinitiation complex;GO:0005852 eukaryotic translation initiation factor 3 complex", "go_biological_process": "GO:0001732 formation of cytoplasmic translation initiation complex", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q0VCU8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q1RMI3-1", "uniprot_id": "GABP1_BOVIN", "mass": 41321.0, "length": 383, "protein_name": "GA-binding protein subunit beta-1", "gene_name": "GABPB1", "organism": "Bovine", "refseq_name": "GA-binding protein subunit beta-1", "refseq_ac": "NP_001069272", "gene_names_uniprotkb": "GABPB1; GABPB2", "gene_names_refseq": "GABPAP; GABPB1; GABPB2", "protein_names_uniprotkb": "GA-binding protein subunit beta-1; GABP subunit beta-1; GABP subunit beta-2; GABPB-1; GABPB-2", "protein_names_refseq": "GA binding protein transcription factor, alpha subunit pseudogene; GA binding protein transcription factor, beta subunit 1; GA-binding protein subunit beta-1; GABP subunit beta-1; GABP subunit beta-2; GABPB-1; GABPB-2", "tax_id": 9913, "disease": "", "pathway": " (bta:520313); (R-BTA-2151201)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Transcription factor capable of interacting with purine rich repeats (GA repeats). Acts as a master regulator of nuclear-encoded mitochondrial genes., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0000976 transcription cis-regulatory region binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0007005 mitochondrion organization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q1RMI3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q29RZ1-1", "uniprot_id": "GALD1_BOVIN", "mass": 23263.0, "length": 220, "protein_name": "Glutamine amidotransferase-like class 1 domain-containing protein 1", "gene_name": "GATD1", "organism": "Bovine", "refseq_name": "glutamine amidotransferase-like class 1 domain-containing protein 1 precursor", "refseq_ac": "NP_001039612", "gene_names_uniprotkb": "GATD1; PDDC1", "gene_names_refseq": "Fy-5; GATD1; PDDC1", "protein_names_uniprotkb": "Glutamine amidotransferase-like class 1 domain-containing protein 1; Ferry endosomal RAB5 effector complex subunit 5; Fy-5; Parkinson disease 7 domain-containing protein 1", "protein_names_refseq": "Parkinson disease 7 domain containing 1; ferry endosomal RAB5 effector complex subunit 5; glutamine amidotransferase like class 1 domain containing 1; glutamine amidotransferase-like class 1 domain-containing protein 1 precursor; glutamine amidotransferase-like class 1 domain-containing protein 1; parkinson disease 7 domain-containing protein 1", "tax_id": 9913, "disease": "", "pathway": " (bta:513454)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of the FERRY complex (Five-subunit Endosomal Rab5 and RNA/ribosome intermediary). The FERRY complex directly interacts with mRNAs and RAB5A, and functions as a RAB5A effector involved in the localization and the distribution of specific mRNAs most likely by mediating their endosomal transport. The complex recruits mRNAs and ribosomes to early endosomes through direct mRNA-interaction., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0019172 glyoxalase III activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0005737 cytoplasm;GO:0005769 early endosome", "go_biological_process": "GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q29RZ1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q1RMK1-1", "uniprot_id": "CBAR2_BOVIN", "mass": 33100.0, "length": 288, "protein_name": "CBY1-interacting BAR domain-containing protein 2", "gene_name": "CIBAR2", "organism": "Bovine", "refseq_name": "CBY1-interacting BAR domain-containing protein 2", "refseq_ac": "NP_001070602", "gene_names_uniprotkb": "CIBAR2; FAM92B", "gene_names_refseq": "CIBAR2; FAM92B", "protein_names_uniprotkb": "CBY1-interacting BAR domain-containing protein 2; Protein FAM92B", "protein_names_refseq": "CBY1-interacting BAR domain-containing protein 2; family with sequence similarity 92 member B; protein FAM92B", "tax_id": 9913, "disease": "", "pathway": " (bta:768078)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "May play a role in ciliogenesis. In cooperation with CBY1 may facilitate ciliogenesis likely by the recruitment and fusion of endosomal vesicles at distal appendages during early stages of ciliogenesis., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A452DIZ7", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005814 centriole;GO:0036064 ciliary basal body;GO:0035869 ciliary transition zone", "go_biological_process": "GO:0060271 cilium assembly", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q1RMK1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q148L1-1", "uniprot_id": "GP108_BOVIN", "mass": 61403.0, "length": 548, "protein_name": "Protein GPR108", "gene_name": "GPR108", "organism": "Bovine", "refseq_name": "protein GPR108 precursor", "refseq_ac": "NP_001068801", "gene_names_uniprotkb": "GPR108", "gene_names_refseq": "GPR108", "protein_names_uniprotkb": "Protein GPR108", "protein_names_refseq": "protein GPR108 precursor; protein GPR108", "tax_id": 9913, "disease": "", "pathway": " (bta:507830)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "May play a role in intracellular immune modulation by activating NF-kappaB response and attenuating Toll-like-receptor response., [UniProtKB, UniProtKB]", "predicted_glycosites": 6, "predicted_n_glycosites": 6, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 6, "binding_glycan_count": 0, "secondary_ac_list": "Q0V8H5", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005794 Golgi apparatus;GO:0016020 membrane;GO:0033106 cis-Golgi network membrane;GO:0005802 trans-Golgi network", "go_biological_process": "GO:0050776 regulation of immune response;GO:0034122 negative regulation of toll-like receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q148L1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9XSJ0-1", "uniprot_id": "UCHL5_BOVIN", "mass": 37432.0, "length": 328, "protein_name": "Ubiquitin carboxyl-terminal hydrolase isozyme L5", "gene_name": "UCHL5", "organism": "Bovine", "refseq_name": "ubiquitin carboxyl-terminal hydrolase isozyme L5", "refseq_ac": "NP_776906", "gene_names_uniprotkb": "UCHL5; UCH37", "gene_names_refseq": "UCH37; UCHL5", "protein_names_uniprotkb": "Ubiquitin carboxyl-terminal hydrolase isozyme L5; 3.4.19.12; UCH-L5; Ubiquitin C-terminal hydrolase UCH37; Ubiquitin thioesterase L5", "protein_names_refseq": "UCH-L5; ubiquitin C-terminal hydrolase UCH37; ubiquitin carboxyl-terminal hydrolase L5; ubiquitin carboxyl-terminal hydrolase isozyme L5; ubiquitin thioesterase L5", "tax_id": 9913, "disease": "", "pathway": " (bta:282110); (R-BTA-5689603)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "16906146", "class_list": "", "function": "Neither Uch37 alone nor the Uch37-Adrm1 or Uch37-Adrm1-S1 complexes can hydrolyse di-ubiquitin efficiently; rather, incorporation into the 19S complex is required to enable processing of polyubiquitin chains., [RefSeq, PubMed]; Protease that specifically cleaves 'Lys-48'-linked polyubiquitin chains. Deubiquitinating enzyme associated with the 19S regulatory subunit of the 26S proteasome. Putative regulatory component of the INO80 complex; however is inactive in the INO80 complex and is activated by a transient interaction of the INO80 complex with the proteasome via ADRM1 (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q3MHN9", "ec_number_list": "3.6.4.-;3.4.25.1;3.4.19.12", "go_molecular_function": "GO:0004866 endopeptidase inhibitor activity;GO:0070628 proteasome binding;GO:0004843 cysteine-type deubiquitinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0060382 regulation of DNA strand elongation;GO:0033044 regulation of chromosome organization;GO:0045880 positive regulation of smoothened signaling pathway;GO:0006281 DNA repair;GO:0006310 DNA recombination", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q9XSJ0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KI56-1", "uniprot_id": "CSN7B_BOVIN", "mass": 29595.0, "length": 264, "protein_name": "COP9 signalosome complex subunit 7b", "gene_name": "COPS7B", "organism": "Bovine", "refseq_name": "COP9 signalosome complex subunit 7b", "refseq_ac": "NP_001040077", "gene_names_uniprotkb": "COPS7B", "gene_names_refseq": "COPS7B", "protein_names_uniprotkb": "COP9 signalosome complex subunit 7b; SGN7b; Signalosome subunit 7b", "protein_names_refseq": "COP9 constitutive photomorphogenic homolog subunit 7B; COP9 signalosome complex subunit 7b; SGN7b; signalosome subunit 7b", "tax_id": 9913, "disease": "", "pathway": " (bta:617995); (R-BTA-5696394); (R-BTA-6781823); (R-BTA-8856825); (R-BTA-8951664)", "pathway_count": 5, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, JUN, I-kappa-B-alpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005829 cytosol;GO:0008180 COP9 signalosome;GO:0005654 nucleoplasm", "go_biological_process": "GO:0010387 COP9 signalosome assembly;GO:0000338 protein deneddylation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2KI56-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q1JPD3-1", "uniprot_id": "D2HDH_BOVIN", "mass": 59056.0, "length": 544, "protein_name": "D-2-hydroxyglutarate dehydrogenase, mitochondrial", "gene_name": "D2HGDH; ING5", "organism": "Bovine", "refseq_name": "D-2-hydroxyglutarate dehydrogenase, mitochondrial precursor", "refseq_ac": "NP_001069446", "gene_names_uniprotkb": "D2HGDH; ING5", "gene_names_refseq": "D2HGDH; D2HGD", "protein_names_uniprotkb": "D-2-hydroxyglutarate dehydrogenase, mitochondrial; 1.1.99.39", "protein_names_refseq": "D-2-hydroxyglutarate dehydrogenase, mitochondrial precursor; D-2-hydroxyglutarate dehydrogenase, mitochondrial", "tax_id": 9913, "disease": "", "pathway": " (bta:533003); (bta:614733); (R-BTA-880009)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "Catalyzes the oxidation of D-2-hydroxyglutarate (D-2-HG) to alpha-ketoglutarate (By similarity). Also catalyzes the oxidation of other D-2-hydroxyacids, such as D-malate (D-MAL) and D-lactate (D-LAC) (By similarity). Exhibits high activities towards D-2-HG and D-MAL but a very weak activity towards D-LAC (By similarity)., [UniProtKB, UniProtKB]; Catalyzes the oxidation of D-2-hydroxyglutarate (D-2-HG) to alpha-ketoglutarate. Also catalyzes the oxidation of other D-2-hydroxyacids, such as D-malate (D-MAL) and D-lactate (D-LAC). Exhibits high activities towards D-2-HG and D-MAL but a very weak activity towards D-LAC., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A5PKH4", "ec_number_list": "1.1.99.39", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0071949 FAD binding;GO:0051990 (R)-2-hydroxyglutarate dehydrogenase activity;GO:0050660 flavin adenine dinucleotide binding", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005634 nucleus", "go_biological_process": "GO:0031648 protein destabilization;GO:0006108 malate metabolic process;GO:0006325 chromatin organization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q1JPD3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q148F2-1", "uniprot_id": "AL5AP_BOVIN", "mass": 18028.0, "length": 161, "protein_name": "Arachidonate 5-lipoxygenase-activating protein", "gene_name": "ALOX5AP", "organism": "Bovine", "refseq_name": "arachidonate 5-lipoxygenase-activating protein", "refseq_ac": "NP_001069761", "gene_names_uniprotkb": "ALOX5AP", "gene_names_refseq": "ALOX5AP", "protein_names_uniprotkb": "Arachidonate 5-lipoxygenase-activating protein", "protein_names_refseq": "arachidonate 5-lipoxygenase-activating protein", "tax_id": 9913, "disease": "", "pathway": " (bta:613869); (R-BTA-2142688); (R-BTA-2142691); (R-BTA-2142700)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "20072847", "class_list": "", "function": "ALOX5AP, CPNE3, IL1R2, IL6, TLR2, TLR4, and THY1 were upregulated in blood polymorphonuclear cells in negative energy balance versus positive energy balance cows., [RefSeq, PubMed]; Required for leukotriene biosynthesis by ALOX5 (5-lipoxygenase). Anchors ALOX5 to the membrane. Binds arachidonic acid, and could play an essential role in the transfer of arachidonic acid to ALOX5. Binds to MK-886, a compound that blocks the biosynthesis of leukotrienes., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004364 glutathione transferase activity;GO:0004464 leukotriene-C4 synthase activity;GO:0008047 enzyme activator activity;GO:0050544 arachidonate binding;GO:0004602 glutathione peroxidase activity", "go_cellular_component": "GO:0005635 nuclear envelope;GO:0005783 endoplasmic reticulum;GO:0031965 nuclear membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0019370 leukotriene biosynthetic process;GO:0071277 cellular response to calcium ion;GO:0070207 protein homotrimerization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q148F2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2HJE1-1", "uniprot_id": "WDR91_BOVIN", "mass": 83157.0, "length": 746, "protein_name": "WD repeat-containing protein 91", "gene_name": "WDR91", "organism": "Bovine", "refseq_name": "WD repeat-containing protein 91", "refseq_ac": "NP_001039948", "gene_names_uniprotkb": "WDR91", "gene_names_refseq": "HSPC049; WDR91", "protein_names_uniprotkb": "WD repeat-containing protein 91", "protein_names_refseq": "WD repeat-containing protein 91", "tax_id": 9913, "disease": "", "pathway": " (bta:540606)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Functions as a negative regulator of the PI3 kinase/PI3K activity associated with endosomal membranes via BECN1, a core subunit of the PI3K complex. By modifying the phosphatidylinositol 3-phosphate/PtdInsP3 content of endosomal membranes may regulate endosome fusion, recycling, sorting and early to late endosome transport. It is for instance, required for the delivery of cargos like BST2/tetherin from early to late endosome and thereby participates indirectly to their degradation by the lysosome. May play a role in meiosis., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0035014 phosphatidylinositol 3-kinase regulator activity;GO:0141039 phosphatidylinositol 3-kinase inhibitor activity", "go_cellular_component": "GO:0005829 cytosol;GO:0031902 late endosome membrane;GO:0031901 early endosome membrane;GO:0010008 endosome membrane", "go_biological_process": "GO:0045022 early endosome to late endosome transport;GO:0051898 negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction;GO:0042176 regulation of protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2HJE1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2HJ75-1", "uniprot_id": "RITA1_BOVIN", "mass": 29087.0, "length": 269, "protein_name": "RBPJ-interacting and tubulin-associated protein 1", "gene_name": "RITA1", "organism": "Bovine", "refseq_name": "RBPJ-interacting and tubulin-associated protein 1", "refseq_ac": "NP_001039809", "gene_names_uniprotkb": "RITA1; RITA", "gene_names_refseq": "C12orf52; C17H12orf52; RITA1; RITA", "protein_names_uniprotkb": "RBPJ-interacting and tubulin-associated protein 1; RBPJ-interacting and tubulin-associated protein", "protein_names_refseq": "RBPJ-interacting and tubulin-associated protein 1", "tax_id": 9913, "disease": "", "pathway": " (bta:533158)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Tubulin-binding protein that acts as a negative regulator of Notch signaling pathway. Shuttles between the cytoplasm and the nucleus and mediates the nuclear export of RBPJ/RBPSUH, thereby preventing the interaction between RBPJ/RBPSUH and NICD product of Notch proteins (Notch intracellular domain), leading to down-regulate Notch-mediated transcription. May play a role in neurogenesis., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0015631 tubulin binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005813 centrosome;GO:0005654 nucleoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0007219 Notch signaling pathway;GO:0051168 nuclear export;GO:0022008 neurogenesis;GO:0045746 negative regulation of Notch signaling pathway;GO:0007399 nervous system development", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2HJ75-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q1JQA4-1", "uniprot_id": "TSN15_BOVIN", "mass": 33091.0, "length": 294, "protein_name": "Tetraspanin-15", "gene_name": "TSPAN15", "organism": "Bovine", "refseq_name": "tetraspanin-15", "refseq_ac": "NP_001069297", "gene_names_uniprotkb": "TSPAN15", "gene_names_refseq": "TSPAN15", "protein_names_uniprotkb": "Tetraspanin-15; Tspan-15", "protein_names_refseq": "tetraspanin-15; tspan-15", "tax_id": 9913, "disease": "", "pathway": " (bta:522371)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23035126", "class_list": "", "function": "Part of TspanC8 subgroup, composed of 6 members that interact with the transmembrane metalloprotease ADAM10. This interaction is required for ADAM10 exit from the endoplasmic reticulum and for enzymatic maturation and trafficking to the cell surface as well as substrate specificity. Different TspanC8/ADAM10 complexes have distinct substrates. Promotes ADAM10-mediated cleavage of CDH2. Negatively regulates ligand-induced Notch activity probably by regulating ADAM10 activity., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0019899 enzyme binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0031902 late endosome membrane;GO:0009986 cell surface;GO:0097197 tetraspanin-enriched microdomain;GO:0016020 membrane", "go_biological_process": "GO:0051604 protein maturation;GO:0051043 regulation of membrane protein ectodomain proteolysis;GO:0072659 protein localization to plasma membrane;GO:0045746 negative regulation of Notch signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q1JQA4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KIC2-1", "uniprot_id": "ETV1_BOVIN", "mass": 55129.0, "length": 477, "protein_name": "ETS translocation variant 1", "gene_name": "ETV1", "organism": "Bovine", "refseq_name": "ETS translocation variant 1", "refseq_ac": "NP_001039957", "gene_names_uniprotkb": "ETV1", "gene_names_refseq": "ETV1", "protein_names_uniprotkb": "ETS translocation variant 1", "protein_names_refseq": "ETS translocation variant 1; ets variant gene 1", "tax_id": 9913, "disease": "", "pathway": " (bta:540846)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Transcriptional activator that binds to DNA sequences containing the consensus pentanucleotide 5'-CGGA[AT]-3' (By similarity). Required for olfactory dopaminergic neuron differentiation; may directly activate expression of tyrosine hydroxylase (TH) (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0043565 sequence-specific DNA binding;GO:0003700 DNA-binding transcription factor activity;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0030154 cell differentiation;GO:0045893 positive regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2KIC2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q1JQD9-1", "uniprot_id": "LMBL2_BOVIN", "mass": 79081.0, "length": 706, "protein_name": "Lethal(3)malignant brain tumor-like protein 2", "gene_name": "L3MBTL2", "organism": "Bovine", "refseq_name": "lethal(3)malignant brain tumor-like protein 2", "refseq_ac": "NP_001069078", "gene_names_uniprotkb": "L3MBTL2", "gene_names_refseq": "L3MBTL2", "protein_names_uniprotkb": "Lethal(3)malignant brain tumor-like protein 2; L(3)mbt-like protein 2", "protein_names_refseq": "L3MBTL2, polycomb repressive complex 1 subunit; l(3)mbt-like 2 protein; l(3)mbt-like protein 2; lethal(3)malignant brain tumor-like 2 protein; lethal(3)malignant brain tumor-like protein 2", "tax_id": 9913, "disease": "", "pathway": " (bta:513297); (R-BTA-4551638); (R-BTA-8953750)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Its association with a chromatin-remodeling complex suggests that it may contribute to prevent expression of genes that trigger the cell into mitosis. Binds to monomethylated and dimethylated 'Lys-20' on histone H4. Binds histone H3 peptides that are monomethylated or dimethylated on 'Lys-4', 'Lys-9' or 'Lys-27'., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q0V8P8", "ec_number_list": "", "go_molecular_function": "GO:0003682 chromatin binding;GO:0008270 zinc ion binding;GO:0042393 histone binding;GO:0140005 histone H4K20me2 reader activity;GO:1990841 promoter-specific chromatin binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045892 negative regulation of DNA-templated transcription;GO:0006355 regulation of DNA-templated transcription;GO:0006325 chromatin organization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q1JQD9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q148F6-1", "uniprot_id": "ROGDI_BOVIN", "mass": 32320.0, "length": 287, "protein_name": "Protein rogdi homolog", "gene_name": "ROGDI", "organism": "Bovine", "refseq_name": "protein rogdi homolog", "refseq_ac": "NP_001068920", "gene_names_uniprotkb": "ROGDI", "gene_names_refseq": "ROGDI", "protein_names_uniprotkb": "Protein rogdi homolog", "protein_names_refseq": "leucine zipper domain protein; protein rogdi homolog; rogdi homolog", "tax_id": 9913, "disease": "", "pathway": " (bta:510492)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0043291 RAVE complex;GO:0005635 nuclear envelope;GO:0030424 axon;GO:0030425 dendrite;GO:0043204 perikaryon", "go_biological_process": "GO:0007420 brain development;GO:0042475 odontogenesis of dentin-containing tooth;GO:0022008 neurogenesis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q148F6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KI89-1", "uniprot_id": "ARMC9_BOVIN", "mass": 75764.0, "length": 665, "protein_name": "LisH domain-containing protein ARMC9", "gene_name": "ARMC9", "organism": "Bovine", "refseq_name": "lisH domain-containing protein ARMC9", "refseq_ac": "NP_001039883", "gene_names_uniprotkb": "ARMC9", "gene_names_refseq": "ARMC9", "protein_names_uniprotkb": "LisH domain-containing protein ARMC9", "protein_names_refseq": "lisH domain-containing protein ARMC9", "tax_id": 9913, "disease": "", "pathway": " (bta:536462)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Involved in ciliogenesis. It is required for appropriate acetylation and polyglutamylation of ciliary microtubules, and regulation of cilium length (By similarity). Acts as a positive regulator of hedgehog (Hh)signaling (By similarity). May participate in the trafficking and/or retention of GLI2 and GLI3 proteins at the ciliary tip (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0042802 identical protein binding", "go_cellular_component": "GO:0005929 cilium;GO:0005814 centriole;GO:0036064 ciliary basal body;GO:0097542 ciliary tip", "go_biological_process": "GO:0045880 positive regulation of smoothened signaling pathway;GO:0060271 cilium assembly", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2KI89-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q10569-1", "uniprot_id": "CPSF1_BOVIN", "mass": 161214.0, "length": 1444, "protein_name": "Cleavage and polyadenylation specificity factor subunit 1", "gene_name": "CPSF1", "organism": "Bovine", "refseq_name": "cleavage and polyadenylation specificity factor subunit 1", "refseq_ac": "NP_777145", "gene_names_uniprotkb": "CPSF1; CPSF160", "gene_names_refseq": "CPSF1", "protein_names_uniprotkb": "Cleavage and polyadenylation specificity factor subunit 1; CPSF 160 kDa subunit; Cleavage and polyadenylation specificity factor 160 kDa subunit", "protein_names_refseq": "CPSF 160 kDa subunit; cleavage and polyadenylation specific factor 1, 160kDa; cleavage and polyadenylation specificity factor 160 kDa subunit; cleavage and polyadenylation specificity factor 1; cleavage and polyadenylation specificity factor subunit 1", "tax_id": 9913, "disease": "", "pathway": " (bta:282703); (R-BTA-159231); (R-BTA-73856); (R-BTA-77595); (R-BTA-9770562)", "pathway_count": 5, "publication_count": 3, "publication_id_list": "1756731;19509282;7651824", "class_list": "", "function": "Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. This subunit is involved in the RNA recognition step of the polyadenylation reaction (By similarity). May play a role in eye morphogenesis and the development of retinal ganglion cell projections to the midbrain (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Data report that PABPN1 is required to restrict CPSF binding to the AAUAAA sequence and to permit the stimulation of poly(A) polymerase by AAUAAA-bound CPSF to be maintained throughout the elongation reaction., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding;GO:0019899 enzyme binding;GO:0035925 mRNA 3'-UTR AU-rich region binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005847 mRNA cleavage and polyadenylation specificity factor complex", "go_biological_process": "GO:0006397 mRNA processing;GO:0031124 mRNA 3'-end processing", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q10569-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q29S21-1", "uniprot_id": "K2C7_BOVIN", "mass": 51578.0, "length": 466, "protein_name": "Keratin, type II cytoskeletal 7", "gene_name": "KRT7", "organism": "Bovine", "refseq_name": "keratin, type II cytoskeletal 7", "refseq_ac": "NP_001039876", "gene_names_uniprotkb": "KRT7", "gene_names_refseq": "KRT7", "protein_names_uniprotkb": "Keratin, type II cytoskeletal 7; CK-7; Cytokeratin-7; K7; Keratin-7; Type-II keratin Kb7", "protein_names_refseq": "CK-7; K7; cytokeratin-7; keratin, type II cytoskeletal 7; type-II keratin Kb7", "tax_id": 9913, "disease": "", "pathway": " (bta:535697); (R-BTA-6805567); (R-BTA-6809371)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "41018975", "class_list": "", "function": "Blocks interferon-dependent interphase and stimulates DNA synthesis in cells., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 8, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0030280 structural constituent of skin epidermis", "go_cellular_component": "GO:0045095 keratin filament;GO:0005829 cytosol", "go_biological_process": "GO:0031424 keratinization;GO:0045109 intermediate filament organization", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q29S21-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q29RY4-1", "uniprot_id": "RNZ1_BOVIN", "mass": 39979.0, "length": 363, "protein_name": "Zinc phosphodiesterase ELAC protein 1", "gene_name": "ELAC1", "organism": "Bovine", "refseq_name": "zinc phosphodiesterase ELAC protein 1", "refseq_ac": "NP_001039792", "gene_names_uniprotkb": "ELAC1", "gene_names_refseq": "ELAC1", "protein_names_uniprotkb": "Zinc phosphodiesterase ELAC protein 1; 3.1.26.11; ElaC homolog protein 1; RNase Z 1; Ribonuclease Z 1; tRNA 3 endonuclease 1; tRNase Z 1", "protein_names_refseq": "RNase Z 1; elaC homolog 1; elaC homolog protein 1; ribonuclease Z 1; tRNA 3 endonuclease 1; tRNase Z 1; zinc phosphodiesterase ELAC protein 1", "tax_id": 9913, "disease": "", "pathway": " (bta:532568)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Specifically involved in tRNA repair: acts downstream of the ribosome-associated quality control (RQC) pathway by removing a 2',3'-cyclic phosphate from tRNAs following cleavage by ANKZF1. tRNAs are then processed by TRNT1., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0046872 metal ion binding;GO:0042781 3'-tRNA processing endoribonuclease activity;GO:0004549 tRNA-specific ribonuclease activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0072344 rescue of stalled ribosome;GO:0042780 tRNA 3'-end processing", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q29RY4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9XS49-1", "uniprot_id": "VEGFB_BOVIN", "mass": 21655.0, "length": 207, "protein_name": "Vascular endothelial growth factor B", "gene_name": "VEGFB", "organism": "Bovine", "refseq_name": "vascular endothelial growth factor B precursor", "refseq_ac": "NP_776912", "gene_names_uniprotkb": "VEGFB; VRF", "gene_names_refseq": "VEGFB", "protein_names_uniprotkb": "Vascular endothelial growth factor B; VEGF-B; VEGF-related factor; VRF", "protein_names_refseq": "VEGF-B; VEGF-related factor; VRF; vascular endothelial growth factor B precursor", "tax_id": 9913, "disease": "", "pathway": " (bta:282121); (R-BTA-114608); (R-BTA-194313); (R-BTA-195399)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "23134302", "class_list": "", "function": "Growth factor for endothelial cells. VEGF-B167 binds heparin and neuropilin-1 whereas the binding to neuropilin-1 of VEGF-B186 is regulated by proteolysis (By similarity)., [UniProtKB]; PCR-SSCP and DNA sequencing methods were applied to reveal 3 SNPs and a duplication in the bovine VEGF-B gene among 675 samples belonging to three native Chinese cattle breeds. Erratum:[Anim Biotechnol. 2013 Jan;24(1):79], [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9GLX2;Q9XS48", "ec_number_list": "", "go_molecular_function": "GO:0008201 heparin binding;GO:0042056 chemoattractant activity;GO:0008083 growth factor activity;GO:0005172 vascular endothelial growth factor receptor binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0016020 membrane;GO:0005576 extracellular region", "go_biological_process": "GO:0001666 response to hypoxia;GO:0051781 positive regulation of cell division;GO:0048010 vascular endothelial growth factor receptor signaling pathway;GO:0002040 sprouting angiogenesis;GO:0050930 induction of positive chemotaxis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q9XS49-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q17QJ3-1", "uniprot_id": "DUS26_BOVIN", "mass": 23767.0, "length": 211, "protein_name": "Dual specificity protein phosphatase 26", "gene_name": "DUSP26", "organism": "Bovine", "refseq_name": "dual specificity protein phosphatase 26", "refseq_ac": "NP_001069472", "gene_names_uniprotkb": "DUSP26", "gene_names_refseq": "DUSP26", "protein_names_uniprotkb": "Dual specificity protein phosphatase 26; 3.1.3.16; 3.1.3.48", "protein_names_refseq": "dual specificity phosphatase 26 (putative); dual specificity protein phosphatase 26", "tax_id": 9913, "disease": "", "pathway": " (bta:533896)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Inactivates MAPK1 and MAPK3 which leads to dephosphorylation of heat shock factor protein 4 and a reduction in its DNA-binding activity., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.1.3.48;3.1.3.16;3.1.3.2;3.1.3.67;3.1.3.21;3.1.3.5;3.1.3.74;3.1.3.52;3.1.3.18;3.1.3.53", "go_molecular_function": "GO:0004722 protein serine/threonine phosphatase activity;GO:0008138 protein tyrosine/serine/threonine phosphatase activity;GO:0033549 MAP kinase phosphatase activity;GO:0004725 protein tyrosine phosphatase activity;GO:0002039 p53 binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005794 Golgi apparatus;GO:0005654 nucleoplasm", "go_biological_process": "GO:0043409 negative regulation of MAPK cascade;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0045785 positive regulation of cell adhesion;GO:0070373 negative regulation of ERK1 and ERK2 cascade", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q17QJ3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KIL4-1", "uniprot_id": "COQ6_BOVIN", "mass": 51072.0, "length": 469, "protein_name": "Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial", "gene_name": "COQ6", "organism": "Bovine", "refseq_name": "ubiquinone biosynthesis monooxygenase COQ6, mitochondrial", "refseq_ac": "NP_001039558", "gene_names_uniprotkb": "COQ6", "gene_names_refseq": "COQ6", "protein_names_uniprotkb": "Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; 1.14.15.45; 1.14.15.46; 2-methoxy-6-polyprenolphenol 4-hydroxylase; Coenzyme Q10 monooxygenase 6", "protein_names_refseq": "2-methoxy-6-polyprenolphenol 4-hydroxylase; coenzyme Q10 monooxygenase 6; coenzyme Q6 homolog, monooxygenase; ubiquinone biosynthesis monooxygenase COQ6, mitochondrial", "tax_id": 9913, "disease": "", "pathway": " (bta:511624); (R-BTA-2142789)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "19393038", "class_list": "", "function": "FAD-dependent monooxygenase required for two non-consecutive steps during ubiquinone biosynthesis. Required for the C5-ring hydroxylation during ubiquinone biosynthesis by catalyzing the hydroxylation of 4-hydroxy-3-(all-trans-decaprenyl)benzoic acid to 3,4-dihydroxy-5-(all-trans-decaprenyl)benzoic acid. Also acts downstream of COQ4, for the C1-hydroxylation during ubiquinone biosynthesis by catalyzing the hydroxylation of 2-methoxy-6-(all-trans-decaprenyl)phenol to 2-methoxy-6-(all-trans-decaprenyl)benzene-1,4-diol. The electrons required for the hydroxylation reaction are funneled indirectly to COQ6 from NADPH via a ferredoxin/ferredoxin reductase system composed of FDX2 and FDXR., [UniProtKB, HAMAP, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "F1MQ68", "ec_number_list": "2.1.1.201;2.7.-.-;1.14.15.45;1.14.15.46", "go_molecular_function": "GO:0071949 FAD binding;GO:0016491 oxidoreductase activity;GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen;GO:0106364 4-hydroxy-3-all-trans-polyprenylbenzoate oxygenase activity;GO:0120538 2-methoxy-6-polyprenolphenol 4-hydroxylase activity", "go_cellular_component": "GO:0031314 extrinsic component of mitochondrial inner membrane;GO:0005739 mitochondrion;GO:0005794 Golgi apparatus;GO:0042995 cell projection", "go_biological_process": "GO:0006744 ubiquinone biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q2KIL4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KID6-1", "uniprot_id": "PLRG1_BOVIN", "mass": 56789.0, "length": 513, "protein_name": "Pleiotropic regulator 1", "gene_name": "PLRG1", "organism": "Bovine", "refseq_name": "pleiotropic regulator 1", "refseq_ac": "NP_001039827", "gene_names_uniprotkb": "PLRG1", "gene_names_refseq": "PLRG1", "protein_names_uniprotkb": "Pleiotropic regulator 1", "protein_names_refseq": "pleiotropic regulator 1 (PRL1 homolog, Arabidopsis); pleiotropic regulator 1", "tax_id": 9913, "disease": "", "pathway": " (bta:533951); (R-BTA-72163)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Involved in pre-mRNA splicing as component of the spliceosome. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0016607 nuclear speck;GO:0031965 nuclear membrane;GO:0001650 fibrillar center;GO:0071013 catalytic step 2 spliceosome", "go_biological_process": "GO:0000398 mRNA splicing, via spliceosome", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2KID6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q1JQC2-1", "uniprot_id": "IR3IP_BOVIN", "mass": 8969.0, "length": 82, "protein_name": "Immediate early response 3-interacting protein 1", "gene_name": "IER3IP1", "organism": "Bovine", "refseq_name": "immediate early response 3-interacting protein 1", "refseq_ac": "NP_001106791", "gene_names_uniprotkb": "IER3IP1", "gene_names_refseq": "IER3IP1", "protein_names_uniprotkb": "Immediate early response 3-interacting protein 1", "protein_names_refseq": "immediate early response 3-interacting protein 1", "tax_id": 9913, "disease": "", "pathway": " (bta:101906131); (bta:768079)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Regulator of endoplasmic reticulum secretion that acts as a key determinant of brain size. Required for secretion of extracellular matrix proteins. Required for correct brain development by depositing sufficient extracellular matrix proteins for tissue integrity and the proliferation of neural progenitors. Acts as a regulator of the unfolded protein response (UPR)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0030134 COPII-coated ER to Golgi transport vesicle;GO:0005789 endoplasmic reticulum membrane;GO:0016020 membrane", "go_biological_process": "GO:2000269 regulation of fibroblast apoptotic process;GO:0015031 protein transport;GO:0050714 positive regulation of protein secretion;GO:0007420 brain development;GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q1JQC2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KI09-1", "uniprot_id": "TCEA3_BOVIN", "mass": 39159.0, "length": 349, "protein_name": "Transcription elongation factor A protein 3", "gene_name": "TCEA3", "organism": "Bovine", "refseq_name": "transcription elongation factor A protein 3", "refseq_ac": "NP_001039825", "gene_names_uniprotkb": "TCEA3", "gene_names_refseq": "TCEA3", "protein_names_uniprotkb": "Transcription elongation factor A protein 3; Transcription elongation factor S-II protein 3", "protein_names_refseq": "transcription elongation factor A (SII), 3; transcription elongation factor A protein 3; transcription elongation factor S-II protein 3", "tax_id": 9913, "disease": "", "pathway": " (bta:533803)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "28161635", "class_list": "", "function": "Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Our results indicated, for the first time, that TCEA3 promotes the differentiation of bovine MDSCs and have implications for meat production and animal rearing., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0003711 transcription elongation factor activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006368 transcription elongation by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q2KI09-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q29RH7-1", "uniprot_id": "TSN12_BOVIN", "mass": 35418.0, "length": 305, "protein_name": "Tetraspanin-12", "gene_name": "TSPAN12", "organism": "Bovine", "refseq_name": "tetraspanin-12", "refseq_ac": "NP_001039977", "gene_names_uniprotkb": "TSPAN12", "gene_names_refseq": "TSPAN12", "protein_names_uniprotkb": "Tetraspanin-12; Tspan-12", "protein_names_refseq": "tetraspanin-12; tspan-12", "tax_id": 9913, "disease": "", "pathway": " (bta:613639)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Regulator of cell surface receptor signal transduction. Plays a central role in retinal vascularization by regulating norrin (NDP) signal transduction. Acts in concert with norrin (NDP) to promote FZD4 multimerization and subsequent activation of FZD4, leading to promote accumulation of beta-catenin (CTNNB1) and stimulate LEF/TCF-mediated transcriptional programs. Suprisingly, it only activates the norrin (NDP)-dependent activation of FZD4, while it does not activate the Wnt-dependent activation of FZD4, suggesting the existence of a Wnt-independent signaling that also promote accumulation the beta-catenin (CTNNB1). Acts as a regulator of membrane proteinases such as ADAM10 and MMP14/MT1-MMP. Activates ADAM10-dependent cleavage activity of amyloid precursor protein (APP). Activates MMP14/MT1-MMP-dependent cleavage activity (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0001525 angiogenesis;GO:0007166 cell surface receptor signaling pathway;GO:0010842 retina layer formation;GO:0045765 regulation of angiogenesis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q29RH7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q27956-1", "uniprot_id": "LIF_BOVIN", "mass": 22063.0, "length": 202, "protein_name": "Leukemia inhibitory factor", "gene_name": "LIF", "organism": "Bovine", "refseq_name": "leukemia inhibitory factor precursor", "refseq_ac": "NP_776356", "gene_names_uniprotkb": "LIF", "gene_names_refseq": "LIF", "protein_names_uniprotkb": "Leukemia inhibitory factor; LIF; bLIF", "protein_names_refseq": "bLIF; cholinergic differentiation factor; leukemia inhibitory factor (cholinergic differentiation factor); leukemia inhibitory factor precursor", "tax_id": 9913, "disease": "", "pathway": " (bta:280840); (R-BTA-6788467)", "pathway_count": 2, "publication_count": 4, "publication_id_list": "14511776;24687528;37490795;9124702", "class_list": "", "function": "Functions as a cytokine that binds to the LIF receptor complex. The LIF receptor complex indeed consists of two signaling receptor subunits IL6ST/gp130 and LIFR that transduce the signal into the cell (By similarity). Functionally, regulates cell self-renewal, differentiation and survival of embryonic stem cells (ESCs) and is crucial for embryonic implantation (By similarity). Mechanistically, ligand binding to LIFR, induces heterodimerization with IL6ST/gp130 activating JAK tyrosine kinases (JAK1 or JAK2 and to a lesser extent TYK2) bound to their intracellular domains. These kinases subsequently phosphorylate IL6ST/gp130 and LIFR. The tyrosine phosphorylated signaling receptors serve in turn as docking sites for recruitment and activation of signal transducers and activators of transcription (STAT3 and to lesser extent STAT1). In parallel to the activation of the STAT3-pathway, the binding of LIF to the LIF receptor complex leads to the activation of the mitogen-activated protein kinase (MAPK) and the phosphatidylinositol 3-kinase (PI(3)K) pathways. Tyrosine phosphorylation of the p85 subunit of PI(3)K by JAK1 leads to activation of the serine/ threonine kinase AKT (protein kinase B) (By similarity). PI(3)K-dependent signaling is required for efficient self-renewal of murine ES cells, and regulation of ERK activity is functionally important in this response (By similarity). Moreover, induces tyrosine phosphorylation of PTPN11, that associates with IL6ST/gp130-LIFR, which in turn recruits the p85 regulatory subunit of PI(3)K protein kinase, promoting PI3K-AKT activation, and GRB2-RAS-MAPK signaling (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; LIF has the capacity to induce terminal differentiation in leukemic cells. Its activities include the induction of hematopoietic differentiation in normal and myeloid leukemia cells, the induction of neuronal cell differentiation, and the stimulation of acute-phase protein synthesis in hepatocytes., [UniProtKB, UniProtKB]; LIF regulates the expression of miR-27a-3p and HOXA10 in bovine endometrial epithelial cells via STAT3 pathway., [RefSeq, PubMed]; Results suggest that leukemia inhibitory factor and macrophage-colony stimulating factor are produced in the endometrium and may play different roles in early and mid-pregnancy, [RefSeq, PubMed]; Studied the effects of leukemia inhibitory factor (LIF) on bovine oocyte maturation and early embryo development in vitro., [RefSeq, PubMed]", "predicted_glycosites": 6, "predicted_n_glycosites": 5, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 6, "binding_glycan_count": 0, "secondary_ac_list": "O02804;P79116", "ec_number_list": "", "go_molecular_function": "GO:0005125 cytokine activity;GO:0008083 growth factor activity;GO:0005146 leukemia inhibitory factor receptor binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005829 cytosol", "go_biological_process": "GO:0006955 immune response;GO:0008284 positive regulation of cell population proliferation;GO:0030154 cell differentiation;GO:0045595 regulation of cell differentiation;GO:0023051 regulation of signaling", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q27956-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9N179-1", "uniprot_id": "EPB41_BOVIN", "mass": 69258.0, "length": 617, "protein_name": "Protein 4.1", "gene_name": "EPB41", "organism": "Bovine", "refseq_name": "protein 4.1 isoform 8", "refseq_ac": "NP_776736", "gene_names_uniprotkb": "EPB41; E41P", "gene_names_refseq": "EPB41", "protein_names_uniprotkb": "Protein 4.1; 4.1R; Band 4.1; Erythrocyte membrane protein band 4.1; P4.1", "protein_names_refseq": "4.1R; P4.1; erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked); protein 4.1 isoform 8; protein 4.1", "tax_id": 9913, "disease": "", "pathway": " (bta:281753); (R-BTA-6794361)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "18373558;24144699", "class_list": "", "function": "4.1G interacts with a subset of CNG channels and implicate this protein-protein interaction in organizing the spatial arrangement of CNG channels in the plasma membrane of retinal outer segments., [RefSeq, PubMed]; Band 4.1 protein is found in a retinal cDNA library screened for proteins interacting with the intracellular C-terminus of the metabotropic glutamate receptor isoform 8a (mGluR8a)., [RefSeq, PubMed]; Protein 4.1 is a major structural element of the erythrocyte membrane skeleton. It plays a key role in regulating membrane physical properties of mechanical stability and deformability by stabilizing spectrin-actin interaction. Recruits DLG1 to membranes. Required for dynein-dynactin complex and NUMA1 recruitment at the mitotic cell cortex during anaphase., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 13, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003779 actin binding;GO:0005516 calmodulin binding;GO:0005198 structural molecule activity;GO:0005200 structural constituent of cytoskeleton;GO:0051219 phosphoprotein binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005856 cytoskeleton;GO:0005886 plasma membrane;GO:0005938 cell cortex;GO:0016323 basolateral plasma membrane", "go_biological_process": "GO:0051301 cell division;GO:0051924 regulation of calcium ion transport;GO:0031032 actomyosin structure organization;GO:0030866 cortical actin cytoskeleton organization;GO:1904778 positive regulation of protein localization to cell cortex", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q9N179-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KIB6-1", "uniprot_id": "LIN7B_BOVIN", "mass": 22280.0, "length": 201, "protein_name": "Protein lin-7 homolog B", "gene_name": "LIN7B", "organism": "Bovine", "refseq_name": "protein lin-7 homolog B", "refseq_ac": "NP_001040042", "gene_names_uniprotkb": "LIN7B", "gene_names_refseq": "LIN7B", "protein_names_uniprotkb": "Protein lin-7 homolog B; Lin-7B", "protein_names_refseq": "lin-7B; protein lin-7 homolog B", "tax_id": 9913, "disease": "", "pathway": " (bta:616283); (R-BTA-212676); (R-BTA-5666185)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. Forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains. The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C), CASK and APBA1 associates with the motor protein KIF17 to transport vesicles containing N-methyl-D-aspartate (NMDA) receptor subunit NR2B along microtubules (By similarity). This complex may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. Ensures the proper localization of GRIN2B (subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may function in localizing synaptic vesicles at synapses where it is recruited by beta-catenin and cadherin. Required to localize Kir2 channels, GABA transporter (SLC6A12) and EGFR/ERBB1, ERBB2, ERBB3 and ERBB4 to the basolateral membrane of epithelial cells. May increase the amplitude of ASIC3 acid-evoked currents by stabilizing the channel at the cell surface (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0030674 protein-macromolecule adaptor activity", "go_cellular_component": "GO:0005911 cell-cell junction;GO:0005923 bicellular tight junction;GO:0016323 basolateral plasma membrane;GO:0045202 synapse;GO:0098793 presynapse", "go_biological_process": "GO:0015031 protein transport;GO:0007269 neurotransmitter secretion;GO:0006887 exocytosis;GO:0048489 synaptic vesicle transport;GO:0008582 regulation of synaptic assembly at neuromuscular junction", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2KIB6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9GLM4-1", "uniprot_id": "TENS1_BOVIN", "mass": 202059.0, "length": 1883, "protein_name": "Tensin-1", "gene_name": "TNS1", "organism": "Bovine", "refseq_name": "tensin-1 isoform 5", "refseq_ac": "NP_001421792", "gene_names_uniprotkb": "TNS1; TNS", "gene_names_refseq": "TNS1; TNS", "protein_names_uniprotkb": "Tensin-1; 3.1.3.-", "protein_names_refseq": "tensin-1 isoform 5", "tax_id": 9913, "disease": "", "pathway": " (bta:286798)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "11023826", "class_list": "", "function": "May act as a protein phosphatase and/or a lipid phosphatase. Involved in fibrillar adhesion formation. Essential for myofibroblast differentiation and myofibroblast-mediated extracellular matrix deposition. Enhances RHOA activation in the presence of DLC1. Plays a role in cell polarization and migration. May be involved in cartilage development and in linking signal transduction pathways to the cytoskeleton., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 5, "predicted_n_glycosites": 0, "predicted_o_glycosites": 5, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 29, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "A0A3Q1LRQ8;A0A3Q1NDB6", "ec_number_list": "", "go_molecular_function": "GO:0003779 actin binding;GO:0008270 zinc ion binding;GO:0004721 phosphoprotein phosphatase activity", "go_cellular_component": "GO:0005856 cytoskeleton;GO:0005925 focal adhesion;GO:0009986 cell surface", "go_biological_process": "GO:0010761 fibroblast migration", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q9GLM4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q29S11-1", "uniprot_id": "NUCKS_BOVIN", "mass": 27237.0, "length": 243, "protein_name": "Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1", "gene_name": "NUCKS1", "organism": "Bovine", "refseq_name": "nuclear ubiquitous casein and cyclin-dependent kinase substrate 1", "refseq_ac": "NP_001039385", "gene_names_uniprotkb": "NUCKS1", "gene_names_refseq": "NUCKS1", "protein_names_uniprotkb": "Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1", "protein_names_refseq": "nuclear ubiquitous casein and cyclin-dependent kinase substrate 1; nuclear ubiquitous casein and cyclin-dependent kinases substrate", "tax_id": 9913, "disease": "", "pathway": " (bta:505585)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Chromatin-associated protein involved in DNA repair by promoting homologous recombination (HR). Binds double-stranded DNA (dsDNA) and secondary DNA structures, such as D-loop structures, but with less affinity than RAD51AP1., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 23, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003690 double-stranded DNA binding;GO:0003697 single-stranded DNA binding;GO:0003682 chromatin binding;GO:0003713 transcription coactivator activity;GO:0140297 DNA-binding transcription factor binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005694 chromosome;GO:0005654 nucleoplasm;GO:0005730 nucleolus", "go_biological_process": "GO:0000724 double-strand break repair via homologous recombination;GO:0036297 interstrand cross-link repair;GO:0060382 regulation of DNA strand elongation;GO:0044829 host-mediated activation of viral genome replication;GO:0045944 positive regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q29S11-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q1LZF2-1", "uniprot_id": "ARP8_BOVIN", "mass": 70485.0, "length": 624, "protein_name": "Actin-related protein 8", "gene_name": "ACTR8", "organism": "Bovine", "refseq_name": "actin-related protein 8", "refseq_ac": "NP_001069829", "gene_names_uniprotkb": "ACTR8; ARP8", "gene_names_refseq": "ACTR8", "protein_names_uniprotkb": "Actin-related protein 8", "protein_names_refseq": "ARP8 actin related protein 8 homolog; actin-related protein 8", "tax_id": 9913, "disease": "", "pathway": " (bta:615133); (R-BTA-5689603); (R-BTA-5696394)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. Required for the recruitment of INO80 (and probably the INO80 complex) to sites of DNA damage Strongly prefer nucleosomes and H3-H4 tetramers over H2A-H2B dimers, suggesting it may act as a nucleosome recognition module within the complex., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003729 mRNA binding;GO:0005524 ATP binding", "go_cellular_component": "GO:0031011 Ino80 complex;GO:0005634 nucleus;GO:0005694 chromosome;GO:0005654 nucleoplasm", "go_biological_process": "GO:0033044 regulation of chromosome organization;GO:0006310 DNA recombination;GO:0006351 DNA-templated transcription;GO:0051301 cell division;GO:0006355 regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q1LZF2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9MZL7-1", "uniprot_id": "CACB1_BOVIN", "mass": 65749.0, "length": 598, "protein_name": "Voltage-dependent L-type calcium channel subunit beta-1", "gene_name": "CACNB1", "organism": "Bovine", "refseq_name": "voltage-dependent L-type calcium channel subunit beta-1", "refseq_ac": "NP_787013", "gene_names_uniprotkb": "CACNB1", "gene_names_refseq": "CACNB1", "protein_names_uniprotkb": "Voltage-dependent L-type calcium channel subunit beta-1; CAB1; Calcium channel voltage-dependent subunit beta 1", "protein_names_refseq": "CAB1; calcium channel voltage-dependent subunit beta 1; calcium channel, voltage-dependent, beta 1 subunit; voltage-dependent L-type calcium channel subunit beta-1", "tax_id": 9913, "disease": "", "pathway": " (bta:327703); (R-BTA-112308); (R-BTA-5576892); (R-BTA-5576893)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "10684870", "class_list": "", "function": "Regulatory subunit of L-type calcium channels (PubMed:10684870). Regulates the activity of L-type calcium channels that contain CACNA1A as pore-forming subunit (By similarity). Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit and increases the presence of the channel complex at the cell membrane. Required for functional expression L-type calcium channels that contain CACNA1D as pore-forming subunit (By similarity). Regulates the activity of L-type calcium channels that contain CACNA1B as pore-forming subunit (PubMed:10684870)., [UniProtKB, UniProtKB, UniProtKB, PubMed]; Regulatory subunit of L-type calcium channels. Regulates the activity of L-type calcium channels that contain CACNA1A as pore-forming subunit. Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit and increases the presence of the channel complex at the cell membrane. Required for functional expression L-type calcium channels that contain CACNA1D as pore-forming subunit. Regulates the activity of L-type calcium channels that contain CACNA1B as pore-forming subunit., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 7, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q9MZL6", "ec_number_list": "", "go_molecular_function": "GO:0005262 calcium channel activity;GO:0008331 high voltage-gated calcium channel activity;GO:0005245 voltage-gated calcium channel activity;GO:0005246 calcium channel regulator activity", "go_cellular_component": "GO:0045202 synapse;GO:0042383 sarcolemma;GO:0005891 voltage-gated calcium channel complex", "go_biological_process": "GO:0006816 calcium ion transport;GO:0007268 chemical synaptic transmission;GO:1904646 cellular response to amyloid-beta;GO:1902514 regulation of calcium ion transmembrane transport via high voltage-gated calcium channel", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q9MZL7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9BE40-1", "uniprot_id": "MYH1_BOVIN", "mass": 222990.0, "length": 1938, "protein_name": "Myosin-1", "gene_name": "MYH1", "organism": "Bovine", "refseq_name": "myosin-1", "refseq_ac": "NP_776542", "gene_names_uniprotkb": "MYH1", "gene_names_refseq": "MYH1", "protein_names_uniprotkb": "Myosin-1; MyHC-2x; Myosin heavy chain 1; Myosin heavy chain 2x; Myosin heavy chain, skeletal muscle, adult 1", "protein_names_refseq": "myHC-2x; myosin heavy chain 2x; myosin heavy chain, skeletal muscle, adult 1; myosin, heavy chain 1, skeletal muscle, adult; myosin, heavy polypeptide 1, skeletal muscle, adult; myosin-1; type 2x myosin heavy chain", "tax_id": 9913, "disease": "", "pathway": " (bta:281337)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "22653670;31702438", "class_list": "", "function": "Gene and protein expression of myosin heavy chain in Nellore cattle comparing growth or meat tenderness traits., [RefSeq, PubMed]; Required for normal hearing. It plays a role in cochlear amplification of auditory stimuli, likely through the positive regulation of prestin (SLC26A5) activity and outer hair cell (OHC) electromotility., [UniProtKB, UniProtKB]; The yak has significantly lower mRNA levels of CPT, UCP3, and MyHC 1 in biceps femoris than in Yellow cattle. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 36, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005516 calmodulin binding;GO:0005524 ATP binding;GO:0051015 actin filament binding;GO:0000146 microfilament motor activity;GO:0003774 cytoskeletal motor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0032982 myosin filament;GO:0030016 myofibril;GO:0016460 myosin II complex;GO:0016459 myosin complex", "go_biological_process": "GO:0006936 muscle contraction;GO:0007605 sensory perception of sound", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q9BE40-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9XSK7-1", "uniprot_id": "HDGF_BOVIN", "mass": 26604.0, "length": 239, "protein_name": "Hepatoma-derived growth factor", "gene_name": "HDGF", "organism": "Bovine", "refseq_name": "hepatoma-derived growth factor", "refseq_ac": "NP_787026", "gene_names_uniprotkb": "HDGF", "gene_names_refseq": "HDGF", "protein_names_uniprotkb": "Hepatoma-derived growth factor; HDGF", "protein_names_refseq": "hepatoma derived growth factor; hepatoma-derived growth factor (high-mobility group protein 1-like); hepatoma-derived growth factor", "tax_id": 9913, "disease": "", "pathway": " (bta:327953)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "18465786;25009202", "class_list": "", "function": "Acts as a transcriptional repressor (By similarity). Has mitogenic activity for fibroblasts (By similarity). Heparin-binding protein (By similarity)., [UniProtKB, UniProtKB]; HDGF is synthesized similarly by the endometrium and embryo, and it may exert embryotropic effects by autocrine and/or paracrine mechanisms., [RefSeq, PubMed]; Involvement of HDGF during the initiation phase of the apoptotic process downstream from an initiator Caspase and regulation of this protein by phosphorylation in the nucleus, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 9, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0008201 heparin binding;GO:0000166 nucleotide binding;GO:0008083 growth factor activity;GO:0003714 transcription corepressor activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005654 nucleoplasm;GO:0017053 transcription repressor complex", "go_biological_process": "GO:0006338 chromatin remodeling;GO:0006351 DNA-templated transcription;GO:0051781 positive regulation of cell division;GO:0000122 negative regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q9XSK7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9N1R0-1", "uniprot_id": "CABP1_BOVIN", "mass": 25755.0, "length": 226, "protein_name": "Calcium-binding protein 1", "gene_name": "CABP1", "organism": "Bovine", "refseq_name": "calcium-binding protein 1", "refseq_ac": "NP_776679", "gene_names_uniprotkb": "CABP1", "gene_names_refseq": "CABP1", "protein_names_uniprotkb": "Calcium-binding protein 1; CaBP1", "protein_names_refseq": "calcium binding protein 1 (calbrain); calcium-binding protein 1", "tax_id": 9913, "disease": "", "pathway": " (bta:281653)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "10625670;17960496", "class_list": "", "function": "Modulates calcium-dependent activity of inositol 1,4,5-triphosphate receptors (ITPRs). Inhibits agonist-induced intracellular calcium signaling. Enhances inactivation and does not support calcium-dependent facilitation of voltage-dependent P/Q-type calcium channels. Causes calcium-dependent facilitation and inhibits inactivation of L-type calcium channels by binding to the same sites as calmodulin in the C-terminal domain of CACNA1C, but has an opposite effect on channel function. Suppresses the calcium-dependent inactivation of CACNA1D. Inhibits TRPC5 channels. Prevents NMDA receptor-induced cellular degeneration. Required for the normal transfer of light signals through the retina., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; The importance of CaBP1s in modulating the stimulus-secretion coupling in excitable cells., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9N1R1", "ec_number_list": "", "go_molecular_function": "GO:0048306 calcium-dependent protein binding;GO:0005246 calcium channel regulator activity;GO:0005509 calcium ion binding;GO:0008139 nuclear localization sequence binding", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0005856 cytoskeleton;GO:0005886 plasma membrane;GO:0014069 postsynaptic density;GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "GO:0007601 visual perception;GO:0042308 negative regulation of protein import into nucleus;GO:0007602 phototransduction", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q9N1R0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9TU25-1", "uniprot_id": "RAC2_BOVIN", "mass": 21424.0, "length": 192, "protein_name": "Ras-related C3 botulinum toxin substrate 2", "gene_name": "RAC2", "organism": "Bovine", "refseq_name": "ras-related C3 botulinum toxin substrate 2", "refseq_ac": "NP_786986", "gene_names_uniprotkb": "RAC2", "gene_names_refseq": "RAC2", "protein_names_uniprotkb": "Ras-related C3 botulinum toxin substrate 2; 3.6.5.2; p21-Rac2", "protein_names_refseq": "p21-Rac2; ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2); ras-related C3 botulinum toxin substrate 2", "tax_id": 9913, "disease": "", "pathway": " (bta:327671); (R-BTA-114604); (R-BTA-1222556); (R-BTA-1257604); (R-BTA-5668599); (R-BTA-6811558); (R-BTA-9013404)", "pathway_count": 7, "publication_count": 1, "publication_id_list": "10802295", "class_list": "", "function": "Plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In its active state, binds to a variety of effector proteins to regulate cellular responses, such as secretory processes, phagocytose of apoptotic cells and epithelial cell polarization. Regulatory subunit of the phagocyte NADPH oxidase complex that mediates the transfer of electrons from cytosolic NADPH to O2 to produce the superoxide anion (O2(-)). Activates PLCG2., [UniProtKB, UniProtKB]; Plays a role in immunological synaptic F-actin density and architecture organization. Regulates actin reorganization in lymphocytes, possibly through the modulation of Rac1 activity. Required for the formation of membrane ruffles during macropinocytosis. Plays a role in cell migration and is required for the formation of cup-like structures during trans-endothelial migration of leukocytes. Binds phospholipids in an activation-dependent manner; thereby acting as an anchor for other proteins to the plasma membrane (PM). Plays a role in exocytosis of cytotoxic granules (CG) by lymphocytes/Component of the exocytosis machinery in natural killer (NK) and CD8+ T cells. Promotes the docking of cytotoxic granules (CG) to the plasma membrane through the interaction with UNC13D. Involved in the cytotoxic activity of lymphocytes/primary CD8+ T cells., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q3T0U8", "ec_number_list": "3.6.5.2;2.7.10.1;2.7.11.1;3.6.5.5;3.1.4.4;3.6.5.-;3.6.5.3;2.7.10.2;2.7.1.153;2.7.1.137;3.6.1.5;3.1.3.48;1.6.3.-;3.6.1.15;3.6.5.4;2.3.2.27", "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0019901 protein kinase binding;GO:0003925 G protein activity;GO:0019887 protein kinase regulator activity", "go_cellular_component": "GO:0005856 cytoskeleton;GO:0005886 plasma membrane;GO:0031410 cytoplasmic vesicle;GO:0042995 cell projection;GO:0043020 NADPH oxidase complex", "go_biological_process": "GO:0006935 chemotaxis;GO:0007015 actin filament organization;GO:0007165 signal transduction;GO:0032956 regulation of actin cytoskeleton organization;GO:0007264 small GTPase-mediated signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q9TU25-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9XT96-1", "uniprot_id": "PSN2_BOVIN", "mass": 50271.0, "length": 449, "protein_name": "Presenilin-2", "gene_name": "PSEN2", "organism": "Bovine", "refseq_name": "presenilin-2", "refseq_ac": "NP_776865", "gene_names_uniprotkb": "PSEN2", "gene_names_refseq": "PSEN2", "protein_names_uniprotkb": "Presenilin-2; 3.4.23.-; PS-2", "protein_names_refseq": "PS-2; presenilin 2 (Alzheimer disease 4); presenilin-2", "tax_id": 9913, "disease": "", "pathway": " (bta:282010); (R-BTA-1251985); (R-BTA-193692); (R-BTA-205043); (R-BTA-3928665); (R-BTA-9839383)", "pathway_count": 6, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid-beta precursor protein). Selectively cleaves late endosomal/lysosomal localized substrates and generates the prominent pool of intracellular amyloid beta that contains longer amyloid beta. The holoprotein functions as a calcium-leak channel that allows the passive movement of calcium from endoplasmic reticulum to cytosol and is involved in calcium homeostasis. Is a regulator of mitochondrion-endoplasmic reticulum membrane tethering and modulates calcium ions shuttling between ER and mitochondria., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q2KI10", "ec_number_list": "2.7.10.1;2.3.2.27;3.4.23.-", "go_molecular_function": "GO:0042500 aspartic endopeptidase activity, intramembrane cleaving", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005813 centrosome;GO:0005765 lysosomal membrane;GO:0005789 endoplasmic reticulum membrane;GO:0031902 late endosome membrane", "go_biological_process": "GO:0035333 Notch receptor processing, ligand-dependent;GO:0006509 membrane protein ectodomain proteolysis;GO:0007219 Notch signaling pathway;GO:0016485 protein processing;GO:0035556 intracellular signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q9XT96-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9XS47-1", "uniprot_id": "PLGF_BOVIN", "mass": 17094.0, "length": 149, "protein_name": "Placenta growth factor", "gene_name": "PGF", "organism": "Bovine", "refseq_name": "placenta growth factor precursor", "refseq_ac": "NP_776375", "gene_names_uniprotkb": "PGF; PLGF", "gene_names_refseq": "PGF; PlGF", "protein_names_uniprotkb": "Placenta growth factor; PlGF", "protein_names_refseq": "placenta growth factor precursor; placenta growth factor; placental growth factor, vascular endothelial growth factor-related protein", "tax_id": 9913, "disease": "", "pathway": " (bta:280894); (R-BTA-194313); (R-BTA-195399)", "pathway_count": 3, "publication_count": 2, "publication_id_list": "15501243;20477802", "class_list": "", "function": "Growth factor active in angiogenesis and endothelial cell growth, stimulating their proliferation and migration. It binds to the receptor FLT1/VEGFR-1. Also promotes cell tumor growth (By similarity)., [UniProtKB]; Placenta growth factor expression is regulated by both VEGF and hyperglycaemia via VEGFR-2, [RefSeq, PubMed]; Study reports polymorphisms in the bovine PGF gene significantly associated with the maternal effect on stillbirth and calving ease in animals under selection., [RefSeq, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "Q2KII8", "ec_number_list": "", "go_molecular_function": "GO:0042056 chemoattractant activity;GO:0008083 growth factor activity;GO:0005172 vascular endothelial growth factor receptor binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0016020 membrane", "go_biological_process": "GO:0008284 positive regulation of cell population proliferation;GO:0030154 cell differentiation;GO:0001666 response to hypoxia;GO:0051781 positive regulation of cell division;GO:0048010 vascular endothelial growth factor receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q9XS47-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9XSK2-1", "uniprot_id": "CD63_BOVIN", "mass": 25752.0, "length": 237, "protein_name": "CD63 antigen", "gene_name": "CD63", "organism": "Bovine", "refseq_name": "CD63 antigen", "refseq_ac": "NP_991372", "gene_names_uniprotkb": "CD63", "gene_names_refseq": "CD63", "protein_names_uniprotkb": "CD63 antigen", "protein_names_refseq": "CD63 antigen", "tax_id": 9913, "disease": "", "pathway": " (bta:404156); (R-BTA-114608); (R-BTA-6798695)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "10398809", "class_list": "", "function": "Functions as a cell surface receptor for TIMP1 and plays a role in the activation of cellular signaling cascades. Plays a role in the activation of ITGB1 and integrin signaling, leading to the activation of AKT, FAK/PTK2 and MAP kinases. Promotes cell survival, reorganization of the actin cytoskeleton, cell adhesion, spreading and migration, via its role in the activation of AKT and FAK/PTK2. Plays a role in VEGFA signaling via its role in regulating the internalization of KDR/VEGFR2. Plays a role in intracellular vesicular transport processes, and is required for normal trafficking of the PMEL luminal domain that is essential for the development and maturation of melanocytes. Plays a role in the adhesion of leukocytes onto endothelial cells via its role in the regulation of SELP trafficking. May play a role in mast cell degranulation in response to Ms4a2/FceRI stimulation, but not in mast cell degranulation in response to other stimuli., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 4, "predicted_n_glycosites": 4, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "Q3SZY2", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005576 extracellular region;GO:0005886 plasma membrane;GO:0009986 cell surface;GO:0005765 lysosomal membrane;GO:0031902 late endosome membrane", "go_biological_process": "GO:0015031 protein transport;GO:0016477 cell migration;GO:0007160 cell-matrix adhesion;GO:0035646 endosome to melanosome transport;GO:0002092 positive regulation of receptor internalization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q9XSK2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q29RY9-1", "uniprot_id": "NPL_BOVIN", "mass": 35166.0, "length": 320, "protein_name": "N-acetylneuraminate lyase", "gene_name": "NPL", "organism": "Bovine", "refseq_name": "N-acetylneuraminate lyase", "refseq_ac": "NP_001039443", "gene_names_uniprotkb": "NPL", "gene_names_refseq": "NPL", "protein_names_uniprotkb": "N-acetylneuraminate lyase; 4.1.3.3; N-acetylneuraminate pyruvate-lyase; N-acetylneuraminic acid aldolase; NALase; Sialate lyase; Sialate-pyruvate lyase; Sialic acid aldolase; Sialic acid lyase", "protein_names_refseq": "N-acetylneuraminate lyase; N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase); N-acetylneuraminic acid aldolase; NALase; sialate lyase; sialate-pyruvate lyase; sialic acid aldolase; sialic acid lyase", "tax_id": 9913, "disease": "", "pathway": " (bta:507597); (R-BTA-4085001)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalyzes the cleavage of N-acetylneuraminic acid (sialic acid) to form pyruvate and N-acetylmannosamine via a Schiff base intermediate. It prevents sialic acids from being recycled and returning to the cell surface. Involved in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "4.1.3.3", "go_molecular_function": "GO:0008747 N-acetylneuraminate lyase activity;GO:0042802 identical protein binding", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0005975 carbohydrate metabolic process;GO:0019262 N-acetylneuraminate catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q29RY9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q1RMU7-1", "uniprot_id": "SESQ2_BOVIN", "mass": 28626.0, "length": 259, "protein_name": "Sesquipedalian-2", "gene_name": "PHETA2", "organism": "Bovine", "refseq_name": "sesquipedalian-2", "refseq_ac": "NP_001039401", "gene_names_uniprotkb": "PHETA2; FAM109B", "gene_names_refseq": "FAM109B; IPIP27B; PHETA2; Ses2", "protein_names_uniprotkb": "Sesquipedalian-2; 27 kDa inositol polyphosphate phosphatase interacting protein B; IPIP27B; PH domain-containing endocytic trafficking adaptor 2; Ses2", "protein_names_refseq": "27 kDa inositol polyphosphate phosphatase interacting protein B; family with sequence similarity 109 member B; sesquipedalian-2", "tax_id": 9913, "disease": "", "pathway": " (bta:506148)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Plays a role in endocytic trafficking. Required for receptor recycling from endosomes, both to the trans-Golgi network and the plasma membrane., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0042803 protein homodimerization activity", "go_cellular_component": "GO:0005769 early endosome;GO:0005829 cytosol;GO:0055037 recycling endosome;GO:0030136 clathrin-coated vesicle;GO:0005802 trans-Golgi network", "go_biological_process": "GO:0007032 endosome organization;GO:0001881 receptor recycling;GO:0042147 retrograde transport, endosome to Golgi", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q1RMU7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KII1-1", "uniprot_id": "ATF3_BOVIN", "mass": 20567.0, "length": 181, "protein_name": "Cyclic AMP-dependent transcription factor ATF-3", "gene_name": "ATF3", "organism": "Bovine", "refseq_name": "cyclic AMP-dependent transcription factor ATF-3", "refseq_ac": "NP_001039658", "gene_names_uniprotkb": "ATF3", "gene_names_refseq": "ATF3", "protein_names_uniprotkb": "Cyclic AMP-dependent transcription factor ATF-3; Activating transcription factor 3; cAMP-dependent transcription factor ATF-3", "protein_names_refseq": "cAMP-dependent transcription factor ATF-3; cyclic AMP-dependent transcription factor ATF-3", "tax_id": 9913, "disease": "", "pathway": " (bta:515266)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "18377912;24196350", "class_list": "", "function": "ATF3 appears to affect gonadotropin-stimulated progesterone secretion at a step or steps downstream of PKA signaling and before cholesterol conversion to progesterone., [RefSeq, PubMed]; ATF3 induction by acute hypoxia is mediated by nitric oxide and the JNK pathway in endothelial cells, [RefSeq, PubMed]; This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Represses transcription from promoters with ATF sites (By similarity). It may repress transcription by stabilizing the binding of inhibitory cofactors at the promoter (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0042803 protein homodimerization activity;GO:0046982 protein heterodimerization activity;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:1990622 CHOP-ATF3 complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0010628 positive regulation of gene expression;GO:0070373 negative regulation of ERK1 and ERK2 cascade;GO:0030968 endoplasmic reticulum unfolded protein response", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q2KII1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q1RMT9-1", "uniprot_id": "P3IP1_BOVIN", "mass": 27772.0, "length": 261, "protein_name": "Phosphoinositide-3-kinase-interacting protein 1", "gene_name": "PIK3IP1", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "PIK3IP1; HGFL", "gene_names_refseq": "", "protein_names_uniprotkb": "Phosphoinositide-3-kinase-interacting protein 1; Kringle domain-containing protein HGFL", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (bta:512082)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "Negative regulator of hepatic phosphatidylinositol 3-kinase (PI3K) activity., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q1JPA4", "ec_number_list": "", "go_molecular_function": "GO:0004175 endopeptidase activity;GO:0005102 signaling receptor binding;GO:0141039 phosphatidylinositol 3-kinase inhibitor activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005886 plasma membrane", "go_biological_process": "GO:0051898 negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q1RMT9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9MYW0-1", "uniprot_id": "TRPC6_BOVIN", "mass": 106351.0, "length": 931, "protein_name": "Short transient receptor potential channel 6", "gene_name": "TRPC6", "organism": "Bovine", "refseq_name": "short transient receptor potential channel 6", "refseq_ac": "NP_001160044", "gene_names_uniprotkb": "TRPC6; TRP6", "gene_names_refseq": "TRPC6; trp6", "protein_names_uniprotkb": "Short transient receptor potential channel 6; TrpC6", "protein_names_refseq": "short transient receptor potential channel 6", "tax_id": 9913, "disease": "", "pathway": " (bta:407151); (R-BTA-114508); (R-BTA-139853); (R-BTA-3295583)", "pathway_count": 4, "publication_count": 5, "publication_id_list": "10816590;18495872;19393038;26858457;34509476", "class_list": "", "function": "Activation of the cytosolic calcium-independent phospholipase A2 beta isoform contributes to TRPC6 externalization via release of arachidonic acid., [RefSeq, PubMed]; Analysis of a TRPC6-TRPC5 channel cascade that restricts endothelial cell movement, [RefSeq, PubMed]; Non-selective, calcium-permeable cation channel. Mediates calcium entry following G(q)-coupled receptor or receptor tyrosine kinase activation, which triggers phospholipase C (PLC)-mediated hydrolysis of phosphatidylinositides and production of diacylglycerol (DAG) that directly activates TRPC6. Does not appear to be activated by depletion of intracellular calcium stores (By similarity). Mediates depolarization of intrinsically photosensitive retinal ganglion cells (ipRGCs) in response to light-induced melanopsin (OPN4)-mediated phototransduction via G(q)-PLC signaling, likely by forming heteromeric TRPC6-TRPC7 channels (By similarity)., [UniProtKB, UniProtKB, UniProtKB]; These findings suggest that lysoPC induces CaM phosphorylation at Tyr(99) by a Src family kinase and that phosphorylated CaM activates PI3K to produce PIP3, which promotes TRPC6 translocation to the cell membrane., [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "F1MND4", "ec_number_list": "2.7.11.1", "go_molecular_function": "GO:0070679 inositol 1,4,5 trisphosphate binding;GO:0042803 protein homodimerization activity;GO:0005261 monoatomic cation channel activity;GO:0015279 store-operated calcium channel activity;GO:0005262 calcium channel activity", "go_cellular_component": "GO:0034703 cation channel complex;GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0036057 slit diaphragm", "go_biological_process": "GO:0051480 regulation of cytosolic calcium ion concentration;GO:0007338 single fertilization;GO:0070588 calcium ion transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q9MYW0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9XSC9-1", "uniprot_id": "TCO2_BOVIN", "mass": 47958.0, "length": 432, "protein_name": "Transcobalamin-2", "gene_name": "TCN2", "organism": "Bovine", "refseq_name": "transcobalamin-2 precursor", "refseq_ac": "NP_776620", "gene_names_uniprotkb": "TCN2", "gene_names_refseq": "TCN2", "protein_names_uniprotkb": "Transcobalamin-2; TC II; TC-2; TCII; Transcobalamin II", "protein_names_refseq": "TC II; TC-2; TCII; macrocytic anemia; transcobalamin II; transcobalamin-2 precursor", "tax_id": 9913, "disease": "", "pathway": " (bta:281518); (R-BTA-9758890)", "pathway_count": 2, "publication_count": 5, "publication_id_list": "10473547;16305752;16537422;17943552;8547333", "class_list": "", "function": "Primary vitamin B12-binding and transport protein. Delivers cobalamin to cells., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Study investigated crystallographically the beta-ligand exchange on Cbl bound to transcobalamin (TC) by crystallization of bovine holo-TC in the presence of either cyanide or sulfite, [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q0V8P0;Q1RMV8;Q58CR7;Q58DL8;Q9TR25", "ec_number_list": "", "go_molecular_function": "GO:0046872 metal ion binding;GO:0031419 cobalamin binding;GO:0140355 cargo receptor ligand activity;GO:0140104 molecular carrier activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005576 extracellular region;GO:0009897 external side of plasma membrane", "go_biological_process": "GO:0015889 cobalamin transport;GO:0006824 cobalt ion transport", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q9XSC9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9XSB5-1", "uniprot_id": "ESR2_BOVIN", "mass": 59032.0, "length": 527, "protein_name": "Estrogen receptor beta", "gene_name": "ESR2", "organism": "Bovine", "refseq_name": "estrogen receptor beta", "refseq_ac": "NP_776476", "gene_names_uniprotkb": "ESR2; NR3A2", "gene_names_refseq": "ERB; ESR2", "protein_names_uniprotkb": "Estrogen receptor beta; ER-beta; Nuclear receptor subfamily 3 group A member 2", "protein_names_refseq": "ER-beta; estrogen receptor 2 (ER beta); estrogen receptor beta; nuclear receptor subfamily 3 group A member 2", "tax_id": 9913, "disease": "", "pathway": " (bta:281146); (R-BTA-1257604); (R-BTA-383280); (R-BTA-6811558); (R-BTA-8939211); (R-BTA-9009391)", "pathway_count": 6, "publication_count": 7, "publication_id_list": "10026117;10432221;12711014;21397601;25363750;29772405;31936899", "class_list": "", "function": "ER-alpha is detected predominantly in the soma whereas ER-beta is only present in the nucleus of a few cells in the frontal cortex., [RefSeq, PubMed]; Missing Information from the Estrogen Receptor Puzzle: Where Are They Localized in Bull Reproductive Tissues and Spermatozoa? Publication Status: Online-Only, [RefSeq, PubMed]; Nuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1ESR1/ER-alpha, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner., [UniProtKB, UniProtKB]; The mRNA expression of ER-alpha and ER-beta in the hypothalamus of developing male and female bovines, is reported., [RefSeq, PubMed]; There are different levels of ERalpha, ERbeta and PR in bovine oviducts at different cycle stages in vivo, [RefSeq, PubMed]; This study examined the calibration of follicular development in chickens and cattle according to gene expression patterns. Unlike mammals, ESR2 was implicated as one of transcription factors regulating CYP19A1 expression in chicken follicles., [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q9TTS2", "ec_number_list": "", "go_molecular_function": "GO:0034056 estrogen response element binding;GO:0008270 zinc ion binding;GO:0019899 enzyme binding;GO:0005496 steroid binding;GO:0004879 nuclear receptor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005739 mitochondrion;GO:0000785 chromatin", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0045893 positive regulation of DNA-templated transcription;GO:0071392 cellular response to estradiol stimulus", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q9XSB5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q95106-1", "uniprot_id": "BDNF_BOVIN", "mass": 28174.0, "length": 250, "protein_name": "Neurotrophic factor BDNF precursor form", "gene_name": "BDNF", "organism": "Bovine", "refseq_name": "neurotrophic factor BDNF precursor form precursor", "refseq_ac": "NP_001040072", "gene_names_uniprotkb": "BDNF", "gene_names_refseq": "BDNF", "protein_names_uniprotkb": "Neurotrophic factor BDNF precursor form; Brain-derived neurotrophic factor; proBDNF", "protein_names_refseq": "neurotrophic factor BDNF precursor form precursor; neurotrophic factor BDNF precursor form; proBDNF", "tax_id": 9913, "disease": "", "pathway": " (bta:617701); (R-BTA-1257604); (R-BTA-6811558); (R-BTA-9026527); (R-BTA-9028731)", "pathway_count": 5, "publication_count": 3, "publication_id_list": "18487493;22015157;9034318", "class_list": "", "function": "During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Expressed in ganglionic neuron-like tumor cells, which may activate an embryonic pathway involving BDNF., [RefSeq, PubMed]; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability (By similarity)., [UniProtKB, UniProtKB, UniProtKB]; Important signaling molecule that activates signaling cascades downstream of NTRK2. Activates signaling cascades via the heterodimeric receptor formed by NGFR and SORCS2. Signaling via NGFR and SORCS2 plays a role in synaptic plasticity and long-term depression (LTD). Binding to NGFR and SORCS2 promotes neuronal apoptosis. Promotes neuronal growth cone collapse., [UniProtKB, UniProtKB]; Important signaling molecule that activates signaling cascades downstream of NTRK2. During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; These observations provided evidence that brain-derived naeurotrophic factor(BDNF) and its receptor (BDNF receptor) secreted by bovine sperm was important in regulation of insulin and leptin., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q32KY2", "ec_number_list": "", "go_molecular_function": "GO:0008083 growth factor activity;GO:0005163 nerve growth factor receptor binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005737 cytoplasm;GO:0048471 perinuclear region of cytoplasm;GO:0008021 synaptic vesicle;GO:0005576 extracellular region", "go_biological_process": "GO:0007169 cell surface receptor protein tyrosine kinase signaling pathway;GO:0048812 neuron projection morphogenesis;GO:0043524 negative regulation of neuron apoptotic process;GO:0050804 modulation of chemical synaptic transmission;GO:0021675 nerve development", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q95106-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9BDK2-1", "uniprot_id": "AIF1_BOVIN", "mass": 16855.0, "length": 147, "protein_name": "Allograft inflammatory factor 1", "gene_name": "AIF1", "organism": "Bovine", "refseq_name": "allograft inflammatory factor 1", "refseq_ac": "NP_776410", "gene_names_uniprotkb": "AIF1", "gene_names_refseq": "AIF1; AIF", "protein_names_uniprotkb": "Allograft inflammatory factor 1; AIF-1", "protein_names_refseq": "AIF-1; allograft inflammatory factor 1; anti-inflammatory factor 1", "tax_id": 9913, "disease": "", "pathway": " (bta:280989)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "12773430;15068062", "class_list": "", "function": "Apoptosis-inducing factor(AIF) was expressed in luminal alveolar cells and in concert with a change in bax protein to bcl-2 protein ratio might contribute to signalling of a change in the dynamic balance of the cell population as lactation progresses(AIF), [RefSeq, PubMed]; May play a role in macrophage activation and function., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0051015 actin filament binding;GO:0005509 calcium ion binding", "go_cellular_component": "GO:0001891 phagocytic cup;GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005856 cytoskeleton", "go_biological_process": "GO:0006911 phagocytosis, engulfment;GO:0006954 inflammatory response;GO:0090026 positive regulation of monocyte chemotaxis;GO:2000406 positive regulation of T cell migration;GO:0051017 actin filament bundle assembly", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q9BDK2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q8WN55-1", "uniprot_id": "PTBP1_BOVIN", "mass": 59535.0, "length": 557, "protein_name": "Polypyrimidine tract-binding protein 1", "gene_name": "PTBP1", "organism": "Bovine", "refseq_name": "polypyrimidine tract-binding protein 1 isoform 1", "refseq_ac": "NP_001289713", "gene_names_uniprotkb": "PTBP1", "gene_names_refseq": "PTBP1; PTB", "protein_names_uniprotkb": "Polypyrimidine tract-binding protein 1; PTB", "protein_names_refseq": "polypyrimidine tract-binding protein 1 isoform 1", "tax_id": 9913, "disease": "", "pathway": " (bta:282018); (R-BTA-6803529); (R-BTA-72163); (R-BTA-72203); (R-BTA-9770562)", "pathway_count": 5, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Plays a role in pre-mRNA splicing and in the regulation of alternative splicing events. Activates exon skipping of its own pre-mRNA during muscle cell differentiation. Binds to the polypyrimidine tract of introns. May promote RNA looping when bound to two separate polypyrimidine tracts in the same pre-mRNA. May promote the binding of U2 snRNP to pre-mRNA. Cooperates with RAVER1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA. Represses the splicing of MAPT/Tau exon 10. Binds to polypyrimidine-rich controlling element (PCE) of CFTR and promotes exon skipping of CFTR exon 9, thereby antagonizing TIA1 and its role in exon inclusion of CFTR exon 9. Plays a role in the splicing of pyruvate kinase PKM by binding repressively to a polypyrimidine tract flanking PKM exon 9, inhibiting exon 9 inclusion and resulting in exon 10 inclusion and production of the PKM M2 isoform., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A3Q1M994", "ec_number_list": "", "go_molecular_function": "GO:0036002 pre-mRNA binding;GO:0003729 mRNA binding;GO:0003723 RNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm", "go_biological_process": "GO:0075522 IRES-dependent viral translational initiation;GO:0006397 mRNA processing;GO:0045665 negative regulation of neuron differentiation;GO:0008380 RNA splicing;GO:0048025 negative regulation of mRNA splicing, via spliceosome", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q8WN55-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q95121-1", "uniprot_id": "PEDF_BOVIN", "mass": 46229.0, "length": 416, "protein_name": "Pigment epithelium-derived factor", "gene_name": "SERPINF1", "organism": "Bovine", "refseq_name": "pigment epithelium-derived factor precursor", "refseq_ac": "NP_776565", "gene_names_uniprotkb": "SERPINF1; PEDF", "gene_names_refseq": "PEDF; SERPINF1", "protein_names_uniprotkb": "Pigment epithelium-derived factor; PEDF; Serpin F1", "protein_names_refseq": "pigment epithelium-derived factor precursor; pigment epithelium-derived factor; serine (or cysteine) proteinase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1; serpin F1", "tax_id": 9913, "disease": "", "pathway": " (bta:281386)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "12779248;15896354;16339148;20219495;30573663;7592790", "class_list": "", "function": "Neurotrophic protein; induces extensive neuronal differentiation in retinoblastoma cells. Potent inhibitor of angiogenesis. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity., [UniProtKB]; PEDF and VEGFR-1 have roles in the negative regulation of angiogenesis, [RefSeq, PubMed]; PEDF inhibits key steps in the angiogenic response of retinal capillary endothelial cells, including cell proliferation and vascular tubule formation. Gene expression of PEDF is negatively regulated by glucose, insulin (via mTOR) and VEGF., [RefSeq, PubMed]; PEDF promotes growth of pericytes through autocrine production of PDGFB., [RefSeq, PubMed]; Results suggest that leptin might elicit angiogenesis through vascular endothelial growth factor induction as well as pigment epithelium-derived factor suppression in pericytes., [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q2KIF6", "ec_number_list": "", "go_molecular_function": "GO:0004867 serine-type endopeptidase inhibitor activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0005615 extracellular space;GO:0042470 melanosome", "go_biological_process": "GO:0016525 negative regulation of angiogenesis;GO:0050769 positive regulation of neurogenesis", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q95121-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q92176-1", "uniprot_id": "COR1A_BOVIN", "mass": 50979.0, "length": 461, "protein_name": "Coronin-1A", "gene_name": "CORO1A", "organism": "Bovine", "refseq_name": "coronin-1A", "refseq_ac": "NP_776946", "gene_names_uniprotkb": "CORO1A; CORO1", "gene_names_refseq": "CORO1A", "protein_names_uniprotkb": "Coronin-1A; Clipin-A; Coronin-like protein A; Coronin-like protein p57; TACO; Tryptophan aspartate-containing coat protein", "protein_names_refseq": "TACO; clipin-A; coronin, actin binding protein, 1A; coronin-1A; coronin-like protein A; coronin-like protein p57; tryptophan aspartate-containing coat protein", "tax_id": 9913, "disease": "", "pathway": " (bta:282196)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "16305752;7758584", "class_list": "", "function": "May be a crucial component of the cytoskeleton of highly motile cells, functioning both in the invagination of large pieces of plasma membrane, as well as in forming protrusions of the plasma membrane involved in cell locomotion. In mycobacteria-infected macrophages, its retention on the phagosomal membrane prevents fusion between phagosomes and lysosomes (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q3SZF9", "ec_number_list": "", "go_molecular_function": "GO:0003785 actin monomer binding;GO:0042803 protein homodimerization activity;GO:0051015 actin filament binding;GO:0032036 myosin heavy chain binding;GO:0043548 phosphatidylinositol 3-kinase binding", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0001891 phagocytic cup;GO:0005769 early endosome;GO:0005884 actin filament;GO:0005886 plasma membrane", "go_biological_process": "GO:0007015 actin filament organization;GO:0016477 cell migration;GO:0031589 cell-substrate adhesion;GO:0050918 positive chemotaxis;GO:0051126 negative regulation of actin nucleation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q92176-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q95M77-1", "uniprot_id": "RHBG_BOVIN", "mass": 49193.0, "length": 455, "protein_name": "Ammonium transporter Rh type B", "gene_name": "RHBG", "organism": "Bovine", "refseq_name": "ammonium transporter Rh type B isoform 1", "refseq_ac": "NP_001421685", "gene_names_uniprotkb": "RHBG", "gene_names_refseq": "RHBG", "protein_names_uniprotkb": "Ammonium transporter Rh type B; Rh family type B glycoprotein; Rh type B glycoprotein; Rhesus blood group family type B glycoprotein", "protein_names_refseq": "Rhesus blood group, B glycoprotein; ammonium transporter Rh type B isoform 1; ammonium transporter Rh type B; rh family type B glycoprotein; rh type B glycoprotein; rhesus blood group family type B glycoprotein", "tax_id": 9913, "disease": "", "pathway": " (bta:282709); (R-BTA-444411)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "11358367", "class_list": "", "function": "Ammonium transporter involved in the maintenance of acid-base homeostasis. Transports ammonium and its related derivative methylammonium across the basolateral plasma membrane of epithelial cells likely contributing to renal transepithelial ammonia transport and ammonia metabolism. May transport either NH4(+) or NH3 ammonia species predominantly mediating an electrogenic NH4(+) transport (By similarity). May act as a CO2 channel providing for renal acid secretion (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A3KMW3", "ec_number_list": "", "go_molecular_function": "GO:0008519 ammonium channel activity;GO:0035379 carbon dioxide transmembrane transporter activity;GO:0030506 ankyrin binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016323 basolateral plasma membrane;GO:0014731 spectrin-associated cytoskeleton", "go_biological_process": "GO:0097272 ammonium homeostasis;GO:0070634 transepithelial ammonium transport;GO:0072488 ammonium transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q95M77-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q8SQA4-1", "uniprot_id": "AGRE5_BOVIN", "mass": 80322.0, "length": 734, "protein_name": "Adhesion G protein-coupled receptor E5", "gene_name": "ADGRE5", "organism": "Bovine", "refseq_name": "adhesion G protein-coupled receptor E5 precursor", "refseq_ac": "NP_788834", "gene_names_uniprotkb": "ADGRE5; CD97", "gene_names_refseq": "ADGRE5; CD97", "protein_names_uniprotkb": "Adhesion G protein-coupled receptor E5; Leukocyte antigen CD97", "protein_names_refseq": "CD97 antigen; CD97 molecule; adhesion G protein-coupled receptor E5 precursor; leukocyte antigen CD97", "tax_id": 9913, "disease": "", "pathway": " (bta:338066)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Receptor potentially involved in both adhesion and signaling processes early after leukocyte activation. Plays an essential role in leukocyte migration., [UniProtKB, UniProtKB]", "predicted_glycosites": 9, "predicted_n_glycosites": 9, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 9, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0005886 plasma membrane", "go_biological_process": "GO:0007155 cell adhesion;GO:0007166 cell surface receptor signaling pathway;GO:0007186 G protein-coupled receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q8SQA4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q8WMY2-1", "uniprot_id": "FPPS_BOVIN", "mass": 40510.0, "length": 353, "protein_name": "Farnesyl pyrophosphate synthase", "gene_name": "FDPS", "organism": "Bovine", "refseq_name": "farnesyl pyrophosphate synthase", "refseq_ac": "NP_803463", "gene_names_uniprotkb": "FDPS", "gene_names_refseq": "FDPS", "protein_names_uniprotkb": "Farnesyl pyrophosphate synthase; (2E,6E)-farnesyl diphosphate synthase; 2.5.1.10; 2.5.1.1; Dimethylallyltranstransferase; FPP synthase; FPS; Farnesyl diphosphate synthase; Geranyltranstransferase", "protein_names_refseq": "(2E,6E)-farnesyl diphosphate synthase; FPP synthase; FPP synthetase; FPS; dimethylallyltranstransferase; farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase); farnesyl diphosphate synthetase; farnesyl pyrophosphate synthase; farnesyl pyrophosphate synthetase; geranyltranstransferase", "tax_id": 9913, "disease": "", "pathway": " (bta:281156)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "11773414", "class_list": "", "function": "Key enzyme in isoprenoid biosynthesis which catalyzes the formation of farnesyl diphosphate (FPP), a precursor for several classes of essential metabolites including sterols, dolichols, carotenoids, and ubiquinones. FPP also serves as substrate for protein farnesylation and geranylgeranylation. Catalyzes the sequential condensation of isopentenyl pyrophosphate with the allylic pyrophosphates, dimethylallyl pyrophosphate, and then with the resultant geranylpyrophosphate to the ultimate product farnesyl pyrophosphate (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A6QPZ8", "ec_number_list": "2.5.1.1;2.5.1.10;2.5.1.29;2.5.1.-", "go_molecular_function": "GO:0004161 dimethylallyltranstransferase activity;GO:0004337 (2E,6E)-farnesyl diphosphate synthase activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005759 mitochondrial matrix;GO:0005777 peroxisome;GO:0031410 cytoplasmic vesicle", "go_biological_process": "GO:0033384 geranyl diphosphate biosynthetic process;GO:0045337 farnesyl diphosphate biosynthetic process;GO:0006695 cholesterol biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q8WMY2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q8WN57-1", "uniprot_id": "TYRP1_BOVIN", "mass": 60617.0, "length": 537, "protein_name": "5,6-dihydroxyindole-2-carboxylic acid oxidase", "gene_name": "TYRP1", "organism": "Bovine", "refseq_name": "5,6-dihydroxyindole-2-carboxylic acid oxidase precursor", "refseq_ac": "NP_776905", "gene_names_uniprotkb": "TYRP1", "gene_names_refseq": "TRP-1; TRP1; TYRP1", "protein_names_uniprotkb": "5,6-dihydroxyindole-2-carboxylic acid oxidase; 1.14.18.-; DHICA oxidase; TRP-1; TRP1; Tyrosinase-related protein 1", "protein_names_refseq": "5,6-dihydroxyindole-2-carboxylic acid oxidase precursor; 5,6-dihydroxyindole-2-carboxylic acid oxidase; DHICA oxidase", "tax_id": 9913, "disease": "", "pathway": " (bta:282105)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "18557975", "class_list": "", "function": "Plays a role in melanin biosynthesis. Catalyzes the oxidation of 5,6-dihydroxyindole-2-carboxylic acid (DHICA) into indole-5,6-quinone-2-carboxylic acid. May regulate or influence the type of melanin synthesized. Also to a lower extent, capable of hydroxylating tyrosine and producing melanin., [UniProtKB, UniProtKB]; Sequence analysis revealed variation in the TYRP1 (exon 5) and MC1R genes; restriction enzyme analysis of these two genes could distinguish between different colours of Hanwoo cattle., [RefSeq, PubMed]", "predicted_glycosites": 6, "predicted_n_glycosites": 6, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 6, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.14.18.1;1.14.18.-", "go_molecular_function": "GO:0042803 protein homodimerization activity;GO:0046872 metal ion binding;GO:0004503 tyrosinase activity", "go_cellular_component": "GO:0097708 intracellular vesicle;GO:0005737 cytoplasm;GO:0042470 melanosome;GO:0033162 melanosome membrane", "go_biological_process": "GO:0032438 melanosome organization;GO:0042438 melanin biosynthetic process;GO:0048023 positive regulation of melanin biosynthetic process;GO:0030318 melanocyte differentiation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q8WN57-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q8WN91-1", "uniprot_id": "CDHR1_BOVIN", "mass": 94290.0, "length": 867, "protein_name": "Cadherin-related family member 1", "gene_name": "CDHR1", "organism": "Bovine", "refseq_name": "cadherin-related family member 1 precursor", "refseq_ac": "NP_777248", "gene_names_uniprotkb": "CDHR1; PCDH21; PRCAD", "gene_names_refseq": "CDHR1; PCDH21; prCAD", "protein_names_uniprotkb": "Cadherin-related family member 1; Photoreceptor cadherin; Protocadherin-21; prCAD", "protein_names_refseq": "cadherin-related family member 1 precursor; photoreceptor cadherin; photoreceptor protocadherin; protocadherin-21", "tax_id": 9913, "disease": "", "pathway": " (bta:281996)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "11738025", "class_list": "", "function": "Potential calcium-dependent cell-adhesion protein. May be required for the structural integrity of the outer segment (OS) of photoreceptor cells (By similarity)., [UniProtKB]", "predicted_glycosites": 5, "predicted_n_glycosites": 4, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005509 calcium ion binding;GO:0045296 cadherin binding;GO:0008013 beta-catenin binding", "go_cellular_component": "GO:0005912 adherens junction;GO:0016342 catenin complex", "go_biological_process": "GO:0016477 cell migration;GO:0000902 cell morphogenesis;GO:0007601 visual perception;GO:0045494 photoreceptor cell maintenance;GO:0007043 cell-cell junction assembly", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q8WN91-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q95104-1", "uniprot_id": "PDYN_BOVIN", "mass": 28790.0, "length": 258, "protein_name": "Proenkephalin-B", "gene_name": "PDYN", "organism": "Bovine", "refseq_name": "proenkephalin-B preproprotein", "refseq_ac": "NP_776564", "gene_names_uniprotkb": "PDYN", "gene_names_refseq": "PDYN", "protein_names_uniprotkb": "Proenkephalin-B; Beta-neoendorphin-dynorphin; Dyn-B; Dynorphin B(1-13); Dynorphin B-29; Dynorphin B; Preprodynorphin", "protein_names_refseq": "beta-neoendorphin-dynorphin; preprodynorphin; proenkephalin-B preproprotein", "tax_id": 9913, "disease": "", "pathway": " (bta:281385)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "23046728;9074507", "class_list": "", "function": "Dynorphin peptides differentially regulate the kappa opioid receptor. Dynorphin A(1-13) has a typical opioid activity, it is 700 times more potent than Leu-enkephalin (By similarity)., [UniProtKB]; Leu-enkephalins compete with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress (By similarity)., [UniProtKB]; Leumorphin has a typical opioid activity and may have anti-apoptotic effect., [UniProtKB]; The investigation of Dyn A 1-17 metabolism at the blood-brain barrier (BBB) is important since the metabolites exhibit unique biological functions compared to the parent compound., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0031628 opioid receptor binding;GO:0001515 opioid peptide activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0005886 plasma membrane;GO:0030425 dendrite;GO:0043025 neuronal cell body;GO:0043679 axon terminus", "go_biological_process": "GO:0007218 neuropeptide signaling pathway;GO:0007268 chemical synaptic transmission;GO:0007600 sensory perception", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q95104-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q95117-1", "uniprot_id": "SFRP3_BOVIN", "mass": 36234.0, "length": 325, "protein_name": "Secreted frizzled-related protein 3", "gene_name": "FRZB", "organism": "Bovine", "refseq_name": "secreted frizzled-related protein 3 precursor", "refseq_ac": "NP_776484", "gene_names_uniprotkb": "FRZB; FRZB1; SFRP3", "gene_names_refseq": "FRZB", "protein_names_uniprotkb": "Secreted frizzled-related protein 3; Frizzled-related protein 1; FrzB-1; sFRP-3", "protein_names_refseq": "frizzled-related protein 1; frzB-1; sFRP-3; secreted frizzled-related protein 3 precursor; secreted frizzled-related protein 3", "tax_id": 9913, "disease": "", "pathway": " (bta:281170)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "8824257;9326585", "class_list": "", "function": "Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP3/FRZB appears to be involved in limb skeletogenesis. Antagonist of Wnt8 signaling. Regulates chondrocyte maturation and long bone development., [UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "Q2KHY0", "ec_number_list": "", "go_molecular_function": "GO:0017147 Wnt-protein binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005737 cytoplasm", "go_biological_process": "GO:0048731 system development;GO:0008285 negative regulation of cell population proliferation;GO:0090090 negative regulation of canonical Wnt signaling pathway;GO:0014033 neural crest cell differentiation;GO:0030308 negative regulation of cell growth", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q95117-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q95118-1", "uniprot_id": "IL2RG_BOVIN", "mass": 43038.0, "length": 379, "protein_name": "Cytokine receptor common subunit gamma", "gene_name": "IL2RG", "organism": "Bovine", "refseq_name": "cytokine receptor common subunit gamma precursor", "refseq_ac": "NP_776784", "gene_names_uniprotkb": "IL2RG", "gene_names_refseq": "IL2RG", "protein_names_uniprotkb": "Cytokine receptor common subunit gamma; IL-2 receptor subunit gamma; IL-2R subunit gamma; IL-2RG; Interleukin-2 receptor subunit gamma; gammaC; p64", "protein_names_refseq": "IL-2 receptor subunit gamma; IL-2R gamma chain; IL-2R subunit gamma; IL-2RG; cytokine receptor common gamma chain; cytokine receptor common subunit gamma precursor; cytokine receptor common subunit gamma; gamma-C; gammaC; interleukin 2 receptor, gamma (severe combined immunodeficiency); interleukin-2 receptor gamma chain; p64", "tax_id": 9913, "disease": "", "pathway": " (bta:281862); (R-BTA-1266695); (R-BTA-5673001); (R-BTA-6785807); (R-BTA-8983432); (R-BTA-8985947); (R-BTA-9020558); (R-BTA-9020958); (R-BTA-912526)", "pathway_count": 9, "publication_count": 2, "publication_id_list": "17675186;8672241", "class_list": "", "function": "Common subunit for the receptors for a variety of interleukins. Probably in association with IL15RA, involved in the stimulation of neutrophil phagocytosis by IL15 (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 5, "predicted_n_glycosites": 5, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "A7YW94", "ec_number_list": "", "go_molecular_function": "GO:0019955 cytokine binding;GO:0004896 cytokine receptor activity;GO:0042010 interleukin-15 receptor activity", "go_cellular_component": "GO:0009986 cell surface;GO:0043235 receptor complex;GO:0009897 external side of plasma membrane", "go_biological_process": "GO:0050766 positive regulation of phagocytosis;GO:0019221 cytokine-mediated signaling pathway;GO:0035723 interleukin-15-mediated signaling pathway;GO:0030098 lymphocyte differentiation;GO:0002639 positive regulation of immunoglobulin production", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q95118-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q95123-1", "uniprot_id": "DHSD_BOVIN", "mass": 17124.0, "length": 158, "protein_name": "Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial", "gene_name": "SDHD", "organism": "Bovine", "refseq_name": "succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial precursor", "refseq_ac": "NP_776604", "gene_names_uniprotkb": "SDHD; SDH4", "gene_names_refseq": "CII-4; CII4; QPs3; SDHD; cybS", "protein_names_uniprotkb": "Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial; CII-4; CybS; Malate dehydrogenase [quinone] cytochrome b small subunit; QPs3; Succinate dehydrogenase complex subunit D; Succinate-ubiquinone reductase membrane anchor subunit", "protein_names_refseq": "malate dehydrogenase [quinone] cytochrome b small subunit; succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial precursor; succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial; succinate dehydrogenase complex, subunit D, integral membrane protein; succinate-ubiquinone reductase membrane anchor subunit", "tax_id": 9913, "disease": "", "pathway": " (bta:281481)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "1864383;2902878;9211943", "class_list": "", "function": "Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q) (By similarity). SDH also oxidizes malate to the non-canonical enol form of oxaloacetate, enol-oxaloacetate (PubMed:1864383, PubMed:2902878). Enol-oxaloacetate, which is a potent inhibitor of the succinate dehydrogenase activity, is further isomerized into keto-oxaloacetate (PubMed:2902878)., [UniProtKB, UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q3T0U6;Q5UAB3", "ec_number_list": "", "go_molecular_function": "GO:0046872 metal ion binding;GO:0020037 heme binding;GO:0048039 ubiquinone binding", "go_cellular_component": "GO:0005743 mitochondrial inner membrane;GO:0045273 respiratory chain complex II (succinate dehydrogenase)", "go_biological_process": "GO:0006099 tricarboxylic acid cycle;GO:0006121 mitochondrial electron transport, succinate to ubiquinone", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q95123-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q95126-1", "uniprot_id": "AVR2B_BOVIN", "mass": 57569.0, "length": 512, "protein_name": "Activin receptor type-2B", "gene_name": "ACVR2B", "organism": "Bovine", "refseq_name": "activin receptor type-2B precursor", "refseq_ac": "NP_776920", "gene_names_uniprotkb": "ACVR2B", "gene_names_refseq": "ACVR2B; ActR-IIB; ActRIIB", "protein_names_uniprotkb": "Activin receptor type-2B; 2.7.11.30; ACTR-IIB; Activin receptor type IIB", "protein_names_refseq": "activin A receptor, type IIB; activin receptor type IIB; activin receptor type-2B precursor; activin receptor type-2B", "tax_id": 9913, "disease": "", "pathway": " (bta:282131)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "9165032", "class_list": "", "function": "Transmembrane serine/threonine kinase activin type-2 receptor forming an activin receptor complex with activin type-1 serine/threonine kinase receptors (ACVR1, ACVR1B or ACVR1c). Transduces the activin signal from the cell surface to the cytoplasm and is thus regulating many physiological and pathological processes including neuronal differentiation and neuronal survival, hair follicle development and cycling, FSH production by the pituitary gland, wound healing, extracellular matrix production, immunosuppression and carcinogenesis. Activin is also thought to have a paracrine or autocrine role in follicular development in the ovary. Within the receptor complex, the type-2 receptors act as a primary activin receptors (binds activin-A/INHBA, activin-B/INHBB as well as inhibin-A/INHA-INHBA). The type-1 receptors like ACVR1B act as downstream transducers of activin signals. Activin binds to type-2 receptor at the plasma membrane and activates its serine-threonine kinase. The activated receptor type-2 then phosphorylates and activates the type-1 receptor. Once activated, the type-1 receptor binds and phosphorylates the SMAD proteins SMAD2 and SMAD3, on serine residues of the C-terminal tail. Soon after their association with the activin receptor and subsequent phosphorylation, SMAD2 and SMAD3 are released into the cytoplasm where they interact with the common partner SMAD4. This SMAD complex translocates into the nucleus where it mediates activin-induced transcription. Inhibitory SMAD7, which is recruited to ACVR1B through FKBP1A, can prevent the association of SMAD2 and SMAD3 with the activin receptor complex, thereby blocking the activin signal. Activin signal transduction is also antagonized by the binding to the receptor of inhibin-B via the IGSF1 inhibin coreceptor (By similarity)., [UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 2, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.11.30", "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0048185 activin binding;GO:0017002 activin receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0048179 activin receptor complex", "go_biological_process": "GO:0071363 cellular response to growth factor stimulus;GO:0032924 activin receptor signaling pathway;GO:0007389 pattern specification process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q95126-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q95136-1", "uniprot_id": "DRD1_BOVIN", "mass": 49317.0, "length": 446, "protein_name": "D(1A) dopamine receptor", "gene_name": "DRD1", "organism": "Bovine", "refseq_name": "D(1A) dopamine receptor", "refseq_ac": "NP_776467", "gene_names_uniprotkb": "DRD1; D1AR", "gene_names_refseq": "DRD1", "protein_names_uniprotkb": "D(1A) dopamine receptor; Dopamine D1 receptor", "protein_names_refseq": "D(1A) dopamine receptor; D1a dopamine receptor; dopamine D1 receptor", "tax_id": 9913, "disease": "", "pathway": " (bta:281125); (R-BTA-390651); (R-BTA-418555)", "pathway_count": 3, "publication_count": 2, "publication_id_list": "12873217;26909995", "class_list": "", "function": "Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase. Forms heterotetramers with DRD3 to potentiate beta-arrestin recruitment and mediate locomotor activity., [UniProtKB, UniProtKB]; There were significant differences in the allelic frequencies among Bos taurus and Bos indicus breeds of different temperament for the DRD1, DRD4, and DRD5 markers. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "A4IFG9;Q8WND7", "ec_number_list": "", "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs", "go_cellular_component": "GO:0005886 plasma membrane;GO:0043197 dendritic spine;GO:0005789 endoplasmic reticulum membrane;GO:0060170 ciliary membrane", "go_biological_process": "GO:0043410 positive regulation of MAPK cascade;GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway;GO:0042311 vasodilation;GO:0007212 G protein-coupled dopamine receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q95136-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q95140-1", "uniprot_id": "RLA0_BOVIN", "mass": 34371.0, "length": 318, "protein_name": "Large ribosomal subunit protein uL10", "gene_name": "RPLP0", "organism": "Bovine", "refseq_name": "large ribosomal subunit protein uL10", "refseq_ac": "NP_001012700", "gene_names_uniprotkb": "RPLP0", "gene_names_refseq": "ARBP; RPLP0", "protein_names_uniprotkb": "Large ribosomal subunit protein uL10; 60S acidic ribosomal protein P0; 60S ribosomal protein L10E", "protein_names_refseq": "60S acidic ribosomal protein P0; 60S ribosomal protein L10E; L10E; acidic ribosomal phosphoprotein P0; large ribosomal subunit protein uL10; ribosomal protein, large, P0", "tax_id": 9913, "disease": "", "pathway": " (bta:286868)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "Ribosomal protein P0 is the functional equivalent of E.coli protein L10., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "O18788;Q3T182;Q5E940", "ec_number_list": "", "go_molecular_function": "GO:0003735 structural constituent of ribosome;GO:0070180 large ribosomal subunit rRNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:1990904 ribonucleoprotein complex;GO:0022625 cytosolic large ribosomal subunit", "go_biological_process": "GO:0042254 ribosome biogenesis;GO:0002181 cytoplasmic translation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q95140-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q95141-1", "uniprot_id": "INAR2_BOVIN", "mass": 59584.0, "length": 530, "protein_name": "Interferon alpha/beta receptor 2", "gene_name": "IFNAR2", "organism": "Bovine", "refseq_name": "interferon alpha/beta receptor 2 precursor", "refseq_ac": "NP_776978", "gene_names_uniprotkb": "IFNAR2; IFNARB", "gene_names_refseq": "IFN-R-2; IFN-R; IFNAR2; IFNBR", "protein_names_uniprotkb": "Interferon alpha/beta receptor 2; IFN-R-2; IFN-alpha/beta receptor 2; Type I interferon receptor 2", "protein_names_refseq": "IFN-alpha-REC; IFN-alpha/beta receptor 2; interferon (alpha, beta and omega) receptor 2; interferon alpha/beta receptor 2 precursor; interferon alpha/beta receptor 2; interferon, beta; interferon-alpha/beta receptor beta chain; receptor; type I interferon receptor 2", "tax_id": 9913, "disease": "", "pathway": " (bta:282258)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "35907379;9348203", "class_list": "", "function": "Specific activation of embryonic IFNAR1 and endometrial IFNAR2 induced by embryonic IFNtau directs normal uterine fate for bovine early implantation., [RefSeq, PubMed]; Together with IFNAR1, forms the heterodimeric receptor for type I interferons (including interferons alpha, beta, epsilon, omega and kappa). Type I interferon binding activates the JAK-STAT signaling cascade, resulting in transcriptional activation or repression of interferon-regulated genes that encode the effectors of the interferon response. Mechanistically, type I interferon-binding brings the IFNAR1 and IFNAR2 subunits into close proximity with one another, driving their associated Janus kinases (JAKs) (TYK2 bound to IFNAR1 and JAK1 bound to IFNAR2) to cross-phosphorylate one another. The activated kinases phosphorylate specific tyrosine residues on the intracellular domains of IFNAR1 and IFNAR2, forming docking sites for the STAT transcription factors (STAT1, STAT2 and STAT). STAT proteins are then phosphorylated by the JAKs, promoting their translocation into the nucleus to regulate expression of interferon-regulated genes., [UniProtKB, UniProtKB]", "predicted_glycosites": 4, "predicted_n_glycosites": 4, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004905 type I interferon receptor activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005886 plasma membrane", "go_biological_process": "GO:0051607 defense response to virus;GO:0060337 type I interferon-mediated signaling pathway;GO:0035455 response to interferon-alpha;GO:0035456 response to interferon-beta", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q95141-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9BDI7-1", "uniprot_id": "MX2_BOVIN", "mass": 81452.0, "length": 710, "protein_name": "Interferon-induced GTP-binding protein Mx2", "gene_name": "MX2", "organism": "Bovine", "refseq_name": "interferon-induced GTP-binding protein Mx2", "refseq_ac": "NP_776366", "gene_names_uniprotkb": "MX2", "gene_names_refseq": "MX2", "protein_names_uniprotkb": "Interferon-induced GTP-binding protein Mx2; Myxovirus resistance protein 2", "protein_names_refseq": "interferon-induced GTP-binding protein Mx2; myxovirus (influenza virus) resistance 2; myxovirus resistance protein 2", "tax_id": 9913, "disease": "", "pathway": " (bta:280873)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "17119954;18062906;23384108;26498202", "class_list": "", "function": "Data indicate that the expression profiles of ISG15, MX1, MX2, and OAS1 could be a useful diagnostic biomarker of gestation. Publication Status: Online-Only, [RefSeq, PubMed]; Interferon-induced dynamin-like GTPase with antiviral activity against vesicular stomatitis virus (VSV)., [UniProtKB, PubMed]; MX1-a, MX1B and MX2 are affected by the type I IFN pathway during pregnancy and are involved in an immune response to protect the mother and fetus, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0008017 microtubule binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005874 microtubule;GO:0005886 plasma membrane;GO:0045202 synapse", "go_biological_process": "GO:0045087 innate immune response;GO:0051607 defense response to virus;GO:0009615 response to virus;GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q9BDI7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9BE39-1", "uniprot_id": "MYH7_BOVIN", "mass": 223229.0, "length": 1935, "protein_name": "Myosin-7", "gene_name": "MYH7", "organism": "Bovine", "refseq_name": "myosin-7", "refseq_ac": "NP_777152", "gene_names_uniprotkb": "MYH7", "gene_names_refseq": "MYH7", "protein_names_uniprotkb": "Myosin-7; MyHC-beta; MyHC-slow; Myosin heavy chain 7; Myosin heavy chain slow isoform; Myosin heavy chain, cardiac muscle beta isoform", "protein_names_refseq": "myHC-beta; myHC-slow; myosin, heavy polypeptide 7, cardiac muscle, beta; myosin-7; type slow/beta myosin heavy chain", "tax_id": 9913, "disease": "", "pathway": " (bta:282714)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "16980359;5058224", "class_list": "", "function": "Myosins are actin-based motor molecules with ATPase activity essential for muscle contraction. Forms regular bipolar thick filaments that, together with actin thin filaments, constitute the fundamental contractile unit of skeletal and cardiac muscle., [UniProtKB, UniProtKB]; Tm affects the conformation of actin so as to increase the area of hydrophobic interaction between actin and myosin molecules, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 8, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005516 calmodulin binding;GO:0005524 ATP binding;GO:0051015 actin filament binding;GO:0000146 microfilament motor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0030017 sarcomere;GO:0032982 myosin filament;GO:0030016 myofibril;GO:0016460 myosin II complex", "go_biological_process": "GO:0030049 muscle filament sliding;GO:0060048 cardiac muscle contraction;GO:0007512 adult heart development", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q9BE39-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9BE41-1", "uniprot_id": "MYH2_BOVIN", "mass": 223319.0, "length": 1940, "protein_name": "Myosin-2", "gene_name": "MYH2", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "MYH2", "gene_names_refseq": "", "protein_names_uniprotkb": "Myosin-2; MyHC-2a; Myosin heavy chain 2a; Myosin heavy chain 2; Myosin heavy chain, skeletal muscle, adult 2", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Myosins are actin-based motor molecules with ATPase activity essential for muscle contraction., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 33, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005516 calmodulin binding;GO:0005524 ATP binding;GO:0051015 actin filament binding;GO:0000146 microfilament motor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0030017 sarcomere;GO:0032982 myosin filament;GO:0030016 myofibril;GO:0016460 myosin II complex", "go_biological_process": "GO:0006936 muscle contraction", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q9BE41-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9BE97-1", "uniprot_id": "ARNT_BOVIN", "mass": 86663.0, "length": 790, "protein_name": "Aryl hydrocarbon receptor nuclear translocator", "gene_name": "ARNT", "organism": "Bovine", "refseq_name": "aryl hydrocarbon receptor nuclear translocator", "refseq_ac": "NP_776418", "gene_names_uniprotkb": "ARNT", "gene_names_refseq": "ARNT", "protein_names_uniprotkb": "Aryl hydrocarbon receptor nuclear translocator; ARNT protein", "protein_names_refseq": "aryl hydrocarbon receptor nuclear translocator", "tax_id": 9913, "disease": "", "pathway": " (bta:281010)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "28904176", "class_list": "", "function": "Transcription factor that functions as an obligate heterodimerization partner for several basic helix-loop-helix PER-ARNT-SIM (bHLH-PAS) proteins. Forms heterodimers with the aryl hydrocarbon receptor (AHR) to mediate the transcriptional response to xenobiotics by binding xenobiotic response elements (XREs) or dioxin response elements (DREs) in target gene promoters. Also heterodimerizes with hypoxia-inducible factor alpha subunits (HIF1A, EPAS1, NPAS1 or NPAS3) to form hypoxia-inducible transcription factors that bind hypoxia response elements (HREs) and activate genes involved in cellular and systemic responses to hypoxia, including angiogenesis, erythropoiesis, and metabolic adaptation (By similarity). Plays a central role in environmental sensing and developmental and physiological regulation of gene expression (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0042803 protein homodimerization activity;GO:0046982 protein heterodimerization activity;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0034751 aryl hydrocarbon receptor complex;GO:0005667 transcription regulator complex;GO:0034753 nuclear aryl hydrocarbon receptor complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0001666 response to hypoxia;GO:0030522 intracellular receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q9BE97-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9BEG2-1", "uniprot_id": "I12R2_BOVIN", "mass": 96208.0, "length": 861, "protein_name": "Interleukin-12 receptor subunit beta-2", "gene_name": "IL12RB2", "organism": "Bovine", "refseq_name": "interleukin-12 receptor subunit beta-2 precursor", "refseq_ac": "NP_777070", "gene_names_uniprotkb": "IL12RB2", "gene_names_refseq": "IL-12RB2; IL12RB2", "protein_names_uniprotkb": "Interleukin-12 receptor subunit beta-2; IL-12 receptor subunit beta-2; IL-12R subunit beta-2; IL-12R-beta-2; IL-12RB2", "protein_names_refseq": "IL-12 receptor beta-2; IL-12 receptor subunit beta-2; IL-12R subunit beta-2; IL-12R-beta-2; interleukin 12 receptor, beta 2; interleukin-12 receptor beta-2 chain; interleukin-12 receptor subunit beta-2 precursor", "tax_id": 9913, "disease": "", "pathway": " (bta:282452)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "12036584;21597988", "class_list": "", "function": "Four SNPs in IFNGR2, IL12RB1, IL12RB2, and IL23R were found to be associated with the MAP infection status of the resource population., [RefSeq, PubMed]; Receptor for interleukin-12. This subunit is the signaling component coupling to the JAK2/STAT4 pathway. On IL12 stimulation, enhances IFN-gamma expression., [UniProtKB]", "predicted_glycosites": 7, "predicted_n_glycosites": 6, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 7, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0019955 cytokine binding;GO:0004896 cytokine receptor activity;GO:0016517 interleukin-12 receptor activity;GO:0019972 interleukin-12 binding", "go_cellular_component": "GO:0043235 receptor complex;GO:0009897 external side of plasma membrane;GO:0042022 interleukin-12 receptor complex", "go_biological_process": "GO:0008284 positive regulation of cell population proliferation;GO:0019221 cytokine-mediated signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q9BEG2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9BG99-1", "uniprot_id": "TREX1_BOVIN", "mass": 33132.0, "length": 315, "protein_name": "Three-prime repair exonuclease 1", "gene_name": "TREX1", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "TREX1", "gene_names_refseq": "", "protein_names_uniprotkb": "Three-prime repair exonuclease 1; 3'-5' exonuclease TREX1; 3.1.11.2", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "10391904", "class_list": "", "function": "Major cellular 3'-to-5' DNA exonuclease which digests single-stranded DNA (ssDNA) and double-stranded DNA (dsDNA) with mismatched 3' termini (PubMed:10391904). Prevents cell-intrinsic initiation of autoimmunity (By similarity). Acts by metabolizing DNA fragments from endogenous retroelements, including L1, LTR and SINE elements (By similarity). Plays a key role in degradation of DNA fragments at cytosolic micronuclei arising from genome instability: its association with the endoplasmic reticulum membrane directs TREX1 to ruptured micronuclei, leading to micronuclear DNA degradation (By similarity). Micronuclear DNA degradation is required to limit CGAS activation and subsequent inflammation (By similarity). Unless degraded, these DNA fragments accumulate in the cytosol and activate the cGAS-STING innate immune signaling, leading to the production of type I interferon (By similarity). Prevents chronic ATM-dependent checkpoint activation, by processing ssDNA polynucleotide species arising from the processing of aberrant DNA replication intermediates (By similarity). Inefficiently degrades oxidized DNA, such as that generated upon antimicrobial reactive oxygen production or upon absorption of UV light (By similarity). During GZMA-mediated cell death, contributes to DNA damage in concert with NME1 (By similarity). NME1 nicks one strand of DNA and TREX1 removes bases from the free 3' end to enhance DNA damage and prevent DNA end reannealing and rapid repair (By similarity)., [UniProtKB, PubMed, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008296 3'-5'-DNA exonuclease activity;GO:0003677 DNA binding;GO:0046872 metal ion binding;GO:0008311 double-stranded DNA 3'-5' DNA exonuclease activity;GO:0008408 3'-5' exonuclease activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006281 DNA repair;GO:0006259 DNA metabolic process;GO:0006308 DNA catabolic process;GO:0045824 negative regulation of innate immune response", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q9BG99-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9BH13-1", "uniprot_id": "CD166_BOVIN", "mass": 64766.0, "length": 583, "protein_name": "CD166 antigen", "gene_name": "ALCAM", "organism": "Bovine", "refseq_name": "CD166 antigen precursor", "refseq_ac": "NP_776663", "gene_names_uniprotkb": "ALCAM", "gene_names_refseq": "ALCAM", "protein_names_uniprotkb": "CD166 antigen; Activated leukocyte cell adhesion molecule", "protein_names_refseq": "CD166 antigen precursor; CD166 antigen; activated leucocyte cell adhesion molecule", "tax_id": 9913, "disease": "", "pathway": " (bta:281614)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "11404380;31650268", "class_list": "", "function": "A genome-wide association study inferred the chip SNP ALCAMc.73+32791A>G as a candidate for Fasciola hepatica resistance., [RefSeq, PubMed]; Cell adhesion molecule that mediates both heterotypic cell-cell contacts via its interaction with CD6, as well as homotypic cell-cell contacts. Promotes T-cell activation and proliferation via its interactions with CD6 (By similarity). Contributes to the formation and maturation of the immunological synapse via its interactions with CD6 (By similarity). Mediates homotypic interactions with cells that express ALCAM. Mediates attachment of dendritic cells onto endothelial cells via homotypic interaction. Inhibits endothelial cell migration and promotes endothelial tube formation via homotypic interactions. Required for normal organization of the lymph vessel network. Required for normal hematopoietic stem cell engraftment in the bone marrow. Plays a role in hematopoiesis; required for normal numbers of hematopoietic stem cells in bone marrow. Promotes in vitro osteoblast proliferation and differentiation (By similarity). Promotes neurite extension, axon growth and axon guidance; axons grow preferentially on surfaces that contain ALCAM (By similarity). Mediates outgrowth and pathfinding for retinal ganglion cell axons (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 9, "predicted_n_glycosites": 9, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 9, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane;GO:0030424 axon;GO:0030425 dendrite;GO:0001772 immunological synapse", "go_biological_process": "GO:0007155 cell adhesion;GO:0031175 neuron projection development;GO:0002250 adaptive immune response;GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:1990138 neuron projection extension", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q9BH13-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9GJW7-1", "uniprot_id": "GBRAP_BOVIN", "mass": 13918.0, "length": 117, "protein_name": "Gamma-aminobutyric acid receptor-associated protein", "gene_name": "GABARAP", "organism": "Bovine", "refseq_name": "gamma-aminobutyric acid receptor-associated protein", "refseq_ac": "NP_001029220", "gene_names_uniprotkb": "GABARAP", "gene_names_refseq": "GABARAP", "protein_names_uniprotkb": "Gamma-aminobutyric acid receptor-associated protein; GABA(A) receptor-associated protein", "protein_names_refseq": "GABA(A) receptor-associated protein; gamma-aminobutyric acid receptor-associated protein", "tax_id": 9913, "disease": "", "pathway": " (bta:327715); (R-BTA-1632852); (R-BTA-8854214)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Ubiquitin-like modifier that plays a role in intracellular transport of GABA(A) receptors and its interaction with the cytoskeleton. Involved in autophagy: while LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation. Through its interaction with the reticulophagy receptor TEX264, participates in the remodeling of subdomains of the endoplasmic reticulum into autophagosomes upon nutrient stress, which then fuse with lysosomes for endoplasmic reticulum turnover. Also required for the local activation of the CUL3(KBTBD6/7) E3 ubiquitin ligase complex, regulating ubiquitination and degradation of TIAM1, a guanyl-nucleotide exchange factor (GEF) that activates RAC1 and downstream signal transduction. Thereby, regulates different biological processes including the organization of the cytoskeleton, cell migration and proliferation. Involved in apoptosis. Participates in selective ER-phagy through interaction with UBAC2, promoting recruitment of UBAC2-associated ER fragments to autophagosomes., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q3SZ82", "ec_number_list": "", "go_molecular_function": "GO:0008017 microtubule binding;GO:0031625 ubiquitin protein ligase binding;GO:0008429 phosphatidylethanolamine binding;GO:0048487 beta-tubulin binding;GO:0050811 GABA receptor binding", "go_cellular_component": "GO:0098982 GABA-ergic synapse;GO:0000139 Golgi membrane;GO:0000421 autophagosome membrane;GO:0005790 smooth endoplasmic reticulum;GO:0005874 microtubule", "go_biological_process": "GO:0097352 autophagosome maturation;GO:0000045 autophagosome assembly;GO:0015031 protein transport;GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0035020 regulation of Rac protein signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q9GJW7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9GK13-1", "uniprot_id": "MUTA_BOVIN", "mass": 83235.0, "length": 750, "protein_name": "Methylmalonyl-CoA mutase, mitochondrial", "gene_name": "MMUT", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "MMUT; MCM; MUT", "gene_names_refseq": "", "protein_names_uniprotkb": "Methylmalonyl-CoA mutase, mitochondrial; 5.4.99.2; MCM; Methylmalonyl-CoA isomerase", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalyzes the reversible isomerization of methylmalonyl-CoA (MMCoA) (generated from branched-chain amino acid metabolism and degradation of dietary odd chain fatty acids and cholesterol) to succinyl-CoA (3-carboxypropionyl-CoA), a key intermediate of the tricarboxylic acid cycle., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "5.4.99.2", "go_molecular_function": "GO:0003924 GTPase activity;GO:0042802 identical protein binding;GO:0042803 protein homodimerization activity;GO:0046872 metal ion binding;GO:0031419 cobalamin binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0006790 sulfur compound metabolic process;GO:0019678 propionate metabolic process, methylmalonyl pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q9GK13-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9GKI7-1", "uniprot_id": "CERT_BOVIN", "mass": 70847.0, "length": 624, "protein_name": "Ceramide transfer protein", "gene_name": "CERT1", "organism": "Bovine", "refseq_name": "ceramide transfer protein", "refseq_ac": "NP_777190", "gene_names_uniprotkb": "CERT1; CERT; COL4A3BP; STARD11", "gene_names_refseq": "CERT1; CERT; COL4A3BP", "protein_names_uniprotkb": "Ceramide transfer protein; CERT; Collagen type IV alpha-3-binding protein; GPBP; Goodpasture antigen-binding protein; START domain-containing protein 11; StAR-related lipid transfer protein 11; StARD11", "protein_names_refseq": "GPBP; START domain-containing protein 11; ceramide transfer protein; collagen type IV alpha 3 binding protein; collagen, type IV, alpha 3 (Goodpasture antigen) binding protein; goodpasture antigen-binding protein; stAR-related lipid transfer protein 11; stARD11", "tax_id": 9913, "disease": "", "pathway": " (bta:286797); (R-BTA-1660661)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "11007769", "class_list": "", "function": "Shelters ceramides inside its steroidogenic acute regulatory lipid transfer (START) domain and mediates their intracellular trafficking in a non-vesicular manner from the endoplasmic reticulum to the Golgi apparatus for conversion to sphingomyelin. Efficiently transfers ceramide molecules having long-chain fatty chains, but not those with very long acyl chains. Capable of transferring diacylglycerol, although with very low efficiency., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 8, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9GKI6", "ec_number_list": "", "go_molecular_function": "GO:1902387 ceramide 1-phosphate binding;GO:1902388 ceramide 1-phosphate transfer activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0005829 cytosol", "go_biological_process": "GO:0035621 ER to Golgi ceramide transport;GO:0120009 intermembrane lipid transfer", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q9GKI7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9GKN7-1", "uniprot_id": "RHAG_BOVIN", "mass": 46719.0, "length": 426, "protein_name": "Ammonium transporter Rh type A", "gene_name": "RHAG", "organism": "Bovine", "refseq_name": "ammonium transporter Rh type A", "refseq_ac": "NP_776596", "gene_names_uniprotkb": "RHAG; RH50", "gene_names_refseq": "RHAG", "protein_names_uniprotkb": "Ammonium transporter Rh type A; Erythrocyte membrane glycoprotein Rh50; Rh family type A glycoprotein; Rh type A glycoprotein; Rhesus blood group family type A glycoprotein", "protein_names_refseq": "Rhesus blood group-associated glycoprotein; ammonium transporter Rh type A; erythrocyte membrane glycoprotein Rh50; rh family type A glycoprotein; rh type A glycoprotein; rhesus blood group family type A glycoprotein", "tax_id": 9913, "disease": "", "pathway": " (bta:281454)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of the ankyrin-1 complex, a multiprotein complex involved in the stability and shape of the erythrocyte membrane. Heterotrimer with RHCE (RHAG)2(RHCE), that transports ammonium and its related derivative methylammonium, in both neutral and ionic forms, across the erythrocyte membrane. The transport of NH4(+) is electrogenic and masks the NH3 transport. Also, may act as a CO2 channel. Moreover in erythrocyte, regulates RHD membrane expression and is associated with rhesus blood group antigen expression., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008519 ammonium channel activity;GO:0035379 carbon dioxide transmembrane transporter activity;GO:0022840 leak channel activity;GO:0015200 methylammonium transmembrane transporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane", "go_biological_process": "GO:0097272 ammonium homeostasis;GO:0055085 transmembrane transport;GO:0015670 carbon dioxide transport;GO:0035378 carbon dioxide transmembrane transport;GO:0006873 intracellular monoatomic ion homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q9GKN7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9GLJ8-1", "uniprot_id": "MC4R_BOVIN", "mass": 36620.0, "length": 332, "protein_name": "Melanocortin receptor 4", "gene_name": "MC4R", "organism": "Bovine", "refseq_name": "melanocortin receptor 4", "refseq_ac": "NP_776535", "gene_names_uniprotkb": "MC4R", "gene_names_refseq": "MC4R", "protein_names_uniprotkb": "Melanocortin receptor 4; MC4-R", "protein_names_refseq": "MC4-R; melanocortin receptor 4", "tax_id": 9913, "disease": "", "pathway": " (bta:281300); (R-BTA-375276); (R-BTA-418555)", "pathway_count": 3, "publication_count": 7, "publication_id_list": "11531696;14592963;18987992;19714485;20563647;21735104;27420995", "class_list": "", "function": "Evaluate the association of single nucleotide polymorphisms (SNPs) in MC4R with milk production traits in water buffalo. Based on the SNP data, seven haplotypes were constructed. Three SNPs H1 (AGT), H2 (GAT), and H3 (GAC) accounted for 93.0% of the total individuals. Statistical analysis indicated that the SNP g.1104C>T was significantly associated with milk yield, protein, and fat percentage. Publication Status: Online-Only, [RefSeq, PubMed]; G protein-coupled receptor that binds melanocyte-stimulating hormones (alpha- and beta-MSH) and corticotropin/ACTH, which are peptide products of the POMC precursor. Functions as a central component of the leptin-melanocortin pathway, which is essential for maintaining energy homeostasis. Upon activation, couples to G(s) protein, stimulating adenylate cyclase and the cAMP-dependent signaling pathway, which promotes anorexogenic signaling in the hypothalamus and contributes to a negative energy balance. Regulates food intake: activation by agonists suppresses appetite, whereas the antagonist Agouti-related protein/AGRP precludes agonist-induced signaling, thereby stimulating appetite. Modulates the firing activity of neurons in paraventricular nucleus (PVN) of the hypothalamus via alpha-MSH and AGRP regulation of inwardly rectifying potassium channel KCNJ13 closure, independently of G(s) signaling. In the PVN, also interacts with opsin 3/OPN3, which couples to G(i/o) proteins to inhibit MC4R-mediated cAMP signaling, thereby promoting food intake. In intestinal epithelial cells, contributes to inhibition of hepatic glucose production via nesfatin-1/NUCB2, leading to increased cAMP levels and glucagon-like peptide 1 (GLP-1) secretion. Interaction with MGRN1 displaces the G(s) protein, further decreasing MC4R signaling activity. Also activated by gamma-MSH, though with low potency., [UniProtKB, UniProtKB]; Results are suggestive that adrenal glucocorticoid production could be regulated through melanocortin 4 receptor, [RefSeq, PubMed]; Single nucleotide polymorphisms in 5'-untranslated region of MC4R gene, were detected., [RefSeq, PubMed]; The MC4R gene may thus be a candidate gene for carcass traits with MC4R single nucleotide polymorphisms being potentially valuable as genetic markers for economic traits in Hanwoo., [RefSeq, PubMed]; The aim was to estimate the frequency of the SNPs in the MC4R gene and to determine if individual genotypes were associated with several economic traits., [RefSeq, PubMed]; The results suggested that -129A>G and 1,069C>G single nucleotide polymorphism of the MC4R gene may be useful as a genetic marker for carcass and meat quality traits in Qinchuan cattle., [RefSeq, PubMed]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "A6QNL9", "ec_number_list": "", "go_molecular_function": "GO:0046872 metal ion binding;GO:0031625 ubiquitin protein ligase binding;GO:0004978 corticotropin receptor activity;GO:0042923 neuropeptide binding;GO:0004980 melanocyte-stimulating hormone receptor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0098804 non-motile cilium membrane", "go_biological_process": "GO:2000252 negative regulation of feeding behavior;GO:1903998 regulation of eating behavior;GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0045780 positive regulation of bone resorption;GO:0060259 regulation of feeding behavior", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "Q9GLJ8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9GLM3-1", "uniprot_id": "RPGR1_BOVIN", "mass": 138434.0, "length": 1221, "protein_name": "X-linked retinitis pigmentosa GTPase regulator-interacting protein 1", "gene_name": "RPGRIP1", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "RPGRIP1", "gene_names_refseq": "", "protein_names_uniprotkb": "X-linked retinitis pigmentosa GTPase regulator-interacting protein 1; RPGR-interacting protein 1", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (bta:282656)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "10958648;12140192;25398945", "class_list": "", "function": "May function as scaffolding protein. Required for normal location of RPGR at the connecting cilium of photoreceptor cells. Required for normal disk morphogenesis and disk organization in the outer segment of photoreceptor cells and for survival of photoreceptor cells., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9GLJ5;Q9GLJ6;Q9GLJ7", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005856 cytoskeleton;GO:0032391 photoreceptor connecting cilium", "go_biological_process": "GO:0007601 visual perception;GO:0046548 retinal rod cell development;GO:1905515 non-motile cilium assembly", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9GLM3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9GLR0-1", "uniprot_id": "NEC2_BOVIN", "mass": 70247.0, "length": 638, "protein_name": "Neuroendocrine convertase 2", "gene_name": "PCSK2", "organism": "Bovine", "refseq_name": "neuroendocrine convertase 2 precursor", "refseq_ac": "NP_776838", "gene_names_uniprotkb": "PCSK2", "gene_names_refseq": "PCSK2", "protein_names_uniprotkb": "Neuroendocrine convertase 2; 3.4.21.94; NEC 2; PC2; Prohormone convertase 2; Proprotein convertase 2", "protein_names_refseq": "NEC 2; PC2; neuroendocrine convertase 2 precursor; neuroendocrine convertase 2; prohormone convertase 2; proprotein convertase 2", "tax_id": 9913, "disease": "", "pathway": " (bta:281968)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "10945231;12401558", "class_list": "", "function": "Prohormone convertase PC2 expression is up-regulated in a cell-specific manner in bovine neuroendocrine ocular ciliary epithelium., [RefSeq, PubMed]; Serine endopeptidase which is involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. Responsible for the release of glucagon from proglucagon in pancreatic A cells. Mediates the release of insulin from proinsulin., [UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004252 serine-type endopeptidase activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0016020 membrane;GO:0043005 neuron projection;GO:0030133 transport vesicle;GO:0070013 intracellular organelle lumen", "go_biological_process": "GO:0006508 proteolysis;GO:0007399 nervous system development;GO:0016486 peptide hormone processing;GO:0016540 protein autoprocessing", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q9GLR0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9GLR1-1", "uniprot_id": "NEC1_BOVIN", "mass": 83807.0, "length": 753, "protein_name": "Neuroendocrine convertase 1", "gene_name": "PCSK1", "organism": "Bovine", "refseq_name": "neuroendocrine convertase 1 precursor", "refseq_ac": "NP_776837", "gene_names_uniprotkb": "PCSK1", "gene_names_refseq": "PC1; PC3; PCSK1", "protein_names_uniprotkb": "Neuroendocrine convertase 1; 3.4.21.93; NEC 1; PC1; Prohormone convertase 1; Proprotein convertase 1", "protein_names_refseq": "NEC 1; neuroendocrine convertase 1 precursor; neuroendocrine convertase 1; prohormone convertase 1; prohormone convertase 3; proprotein convertase 1; subtilisin-like", "tax_id": 9913, "disease": "", "pathway": " (bta:281967)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "10945231;12401558;12950171", "class_list": "", "function": "A model of the membrane topology of the prohomone convertase PC3, where it is anchored to lipid rafts in secretory granule membranes via the transmembrane domain, [RefSeq, PubMed]; Involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. Substrates include POMC, renin, oxytocin, vasopressin, enkephalin, dynorphin, somatostatin, insulin and AGRP., [UniProtKB, UniProtKB]; Prohormone convertase PC1 expression is up-regulated in a cell-specific manner in bovine neuroendocrine ocular ciliary epithelium., [RefSeq, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004252 serine-type endopeptidase activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0016020 membrane;GO:0034774 secretory granule lumen;GO:0043005 neuron projection;GO:0030133 transport vesicle", "go_biological_process": "GO:0016486 peptide hormone processing", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9GLR1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9MYY0-1", "uniprot_id": "HPSE_BOVIN", "mass": 61077.0, "length": 545, "protein_name": "Heparanase", "gene_name": "HPSE", "organism": "Bovine", "refseq_name": "heparanase precursor", "refseq_ac": "NP_776507", "gene_names_uniprotkb": "HPSE", "gene_names_refseq": "HPSE", "protein_names_uniprotkb": "Heparanase; 3.2.1.166", "protein_names_refseq": "heparanase precursor", "tax_id": 9913, "disease": "", "pathway": " (bta:281230)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "11277877;18818292;20164120;28864018", "class_list": "", "function": "Changing placental expression indicates possible involvement in fetomaternal communication and placental maturation, [RefSeq, PubMed]; Endoglycosidase that cleaves heparan sulfate proteoglycans (HSPGs) into heparan sulfate side chains and core proteoglycans. Participates in extracellular matrix (ECM) degradation and remodeling. Selectively cleaves the linkage between a glucuronic acid unit and an N-sulfo glucosamine unit carrying either a 3-O-sulfo or a 6-O-sulfo group. Can also cleave the linkage between a glucuronic acid unit and an N-sulfo glucosamine unit carrying a 2-O-sulfo group, but not linkages between a glucuronic acid unit and a 2-O-sulfated iduronic acid moiety. Essentially inactive at neutral pH but becomes active under acidic conditions such as during tumor invasion and in inflammatory processes. Facilitates cell migration associated with metastasis, wound healing and inflammation. Enhances shedding of syndecans. Acts as a procoagulant by enhancing the generation of activated factor X/F10 in the presence of tissue factor/TF and activated factor VII/F7. Independent of its enzymatic activity, increases cell adhesion to the extracellular matrix (ECM). Enhances AKT1/PKB phosphorylation, possibly via interaction with a lipid raft-resident receptor. Plays a role in the regulation of osteogenesis. Enhances angiogenesis through up-regulation of SRC-mediated activation of VEGF. Implicated in hair follicle inner root sheath differentiation and hair homeostasis (By similarity)., [UniProtKB]; Lutropin induces a transient increase in HPSE mRNA at specific times after its addition., [RefSeq, PubMed]; Suggest that high glucose is a potent stimulator of endothelial heparanase secretion., [RefSeq, PubMed]", "predicted_glycosites": 4, "predicted_n_glycosites": 3, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0030305 heparanase activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005634 nucleus;GO:0031012 extracellular matrix;GO:0005765 lysosomal membrane", "go_biological_process": "GO:0007160 cell-matrix adhesion;GO:0030200 heparan sulfate proteoglycan catabolic process;GO:0060055 angiogenesis involved in wound healing", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q9MYY0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9MZ06-1", "uniprot_id": "FGFP1_BOVIN", "mass": 26188.0, "length": 234, "protein_name": "Fibroblast growth factor-binding protein 1", "gene_name": "FGFBP1", "organism": "Bovine", "refseq_name": "fibroblast growth factor-binding protein 1 precursor", "refseq_ac": "NP_776762", "gene_names_uniprotkb": "FGFBP1; FGFBP", "gene_names_refseq": "FGFBP1; FGFBP", "protein_names_uniprotkb": "Fibroblast growth factor-binding protein 1; FGF-BP1; FGF-BP; FGF-binding protein 1; FGFBP-1", "protein_names_refseq": "FGF-binding protein 1; fibroblast growth factor-binding protein 1 precursor", "tax_id": 9913, "disease": "", "pathway": " (bta:281812); (R-BTA-190377)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "10867016;16257968", "class_list": "", "function": "Acts as a carrier protein that release fibroblast-binding factors (FGFs) from the extracellular matrix (EM) storage and thus enhance the mitogenic activity of FGFs. Enhances FGF2 signaling during tissue repair, angiogenesis and in tumor growth (By similarity)., [UniProtKB]; The FGF interaction domain is contained in the C terminus of FGF-BP1, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 1, "reported_o_glycosites": 1, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 1, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 1, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "Q0IID1", "ec_number_list": "", "go_molecular_function": "GO:0019838 growth factor binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0005886 plasma membrane", "go_biological_process": "GO:0007267 cell-cell signaling;GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis;GO:1903589 positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q9MZ06-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9N0V4-1", "uniprot_id": "GSTM1_BOVIN", "mass": 25635.0, "length": 218, "protein_name": "Glutathione S-transferase Mu 1", "gene_name": "GSTM1", "organism": "Bovine", "refseq_name": "glutathione S-transferase Mu 1", "refseq_ac": "NP_787019", "gene_names_uniprotkb": "GSTM1; GSTM", "gene_names_refseq": "GSTM1; LOC327709", "protein_names_uniprotkb": "Glutathione S-transferase Mu 1; 2.5.1.18; GST class-mu 1; GSTM1-1", "protein_names_refseq": "GST class-mu 1; GSTM1-1; glutathione S-transferase Mu 1", "tax_id": 9913, "disease": "", "pathway": " (bta:327709)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "10973735;26091956", "class_list": "", "function": "Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Protects against the thiol-mediated metal-catalyzed oxidative inactivation of enzymes. Involved in the formation of glutathione conjugates of both prostaglandin A2 (PGA2) and prostaglandin J2 (PGJ2). Participates in the formation of novel hepoxilin regioisomers (By similarity)., [UniProtKB, UniProtKB, PubMed]; Missense mutation (rs135955605) associated with significant decrease of sperm motility and ATP content, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.5.1.18;5.2.1.2;1.20.4.2;1.8.5.1;4.1.1.84;5.3.99.2;1.11.1.-;5.3.3.-;4.4.1.20", "go_molecular_function": "GO:0004364 glutathione transferase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0006693 prostaglandin metabolic process;GO:1901687 glutathione derivative biosynthetic process;GO:0051122 hepoxilin biosynthetic process;GO:0006749 glutathione metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q9N0V4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9N0W2-1", "uniprot_id": "FUT8_BOVIN", "mass": 66493.0, "length": 575, "protein_name": "Alpha-(1,6)-fucosyltransferase", "gene_name": "FUT8", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "FUT8", "gene_names_refseq": "", "protein_names_uniprotkb": "Alpha-(1,6)-fucosyltransferase; 2.4.1.68; Alpha1-6FucT; Fucosyltransferase 8; GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase; GDP-fucose--glycoprotein fucosyltransferase; Glycoprotein 6-alpha-L-fucosyltransferase", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "11070054", "class_list": "", "function": "Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans. Fucosylates the reducing GlcNAc residue in complex-type N-glycans attached on the fragment crystallizable (Fc) of IgGs. Fully converts Fc glycoforms containing one or two terminal GlcNAc moieties (G0-GlcNAc and G0)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.4.1.68", "go_molecular_function": "GO:0046921 alpha-(1->6)-fucosyltransferase activity;GO:0017124 SH3 domain binding;GO:0008424 glycoprotein 6-alpha-L-fucosyltransferase activity", "go_cellular_component": "GO:0032580 Golgi cisterna membrane", "go_biological_process": "GO:0006487 protein N-linked glycosylation;GO:0046368 GDP-L-fucose metabolic process", "synthesized_glycan_count": 6717, "hit_score": 0.2, "record_id": "Q9N0W2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9N1U7-1", "uniprot_id": "OTC_BOVIN", "mass": 39842.0, "length": 354, "protein_name": "Ornithine transcarbamylase, mitochondrial", "gene_name": "OTC", "organism": "Bovine", "refseq_name": "ornithine transcarbamylase, mitochondrial precursor", "refseq_ac": "NP_803453", "gene_names_uniprotkb": "OTC", "gene_names_refseq": "OTC", "protein_names_uniprotkb": "Ornithine transcarbamylase, mitochondrial; 2.1.3.3; OTCase; Ornithine carbamoyltransferase, mitochondrial", "protein_names_refseq": "OTCase; ornithine carbamoyltransferase, mitochondrial; ornithine transcarbamylase, mitochondrial precursor; ornithine transcarbamylase, mitochondrial", "tax_id": 9913, "disease": "", "pathway": " (bta:280887)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalyzes the second step of the urea cycle, the condensation of carbamoyl phosphate with L-ornithine to form L-citrulline. The urea cycle ensures the detoxification of ammonia by converting it to urea for excretion., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.1.3.3", "go_molecular_function": "GO:0004585 ornithine carbamoyltransferase activity;GO:0016597 amino acid binding", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane;GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0019240 citrulline biosynthetic process;GO:0000050 urea cycle;GO:0042450 L-arginine biosynthetic process via ornithine", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q9N1U7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9TT92-1", "uniprot_id": "ATS5_BOVIN", "mass": 22576.0, "length": 207, "protein_name": "A disintegrin and metalloproteinase with thrombospondin motifs 5", "gene_name": "ADAMTS5", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "ADAMTS5", "gene_names_refseq": "", "protein_names_uniprotkb": "A disintegrin and metalloproteinase with thrombospondin motifs 5; 3.4.24.-; ADAM-TS 5; ADAM-TS5; ADAMTS-5; ADMP-2; Aggrecanase-2", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 2, "publication_id_list": "10403768;10625599", "class_list": "", "function": "Metalloproteinase that plays an important role in connective tissue organization, development, inflammation and cell migration. Extracellular matrix (ECM) degrading enzyme that shows proteolytic activity toward the hyalectan group of chondroitin sulfate proteoglycans (CSPGs) including ACAN, VCAN, BCAN and NCAN. Cleavage within the hyalectans occurs at Glu-Xaa recognition motifs. Plays a role in embryonic development, including limb and cardiac morphogenesis, and skeletal muscle development through its VCAN remodeling properties. Cleaves VCAN in the pericellular matrix surrounding myoblasts, facilitating myoblast contact and fusion which is required for skeletal muscle development and regeneration. Participates in the development of brown adipose tissue and browning of white adipose tissue. Plays an important role for T-lymphocyte migration from draining lymph nodes following viral infection., [UniProtKB, UniProtKB]", "predicted_glycosites": 4, "predicted_n_glycosites": 1, "predicted_o_glycosites": 1, "predicted_c_glycosites": 2, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004175 endopeptidase activity;GO:0004222 metalloendopeptidase activity;GO:0008237 metallopeptidase activity;GO:0046872 metal ion binding", "go_cellular_component": "", "go_biological_process": "GO:0006508 proteolysis;GO:0022617 extracellular matrix disassembly;GO:0007520 myoblast fusion", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q9TT92-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9TT94-1", "uniprot_id": "SCD_BOVIN", "mass": 41705.0, "length": 359, "protein_name": "Stearoyl-CoA desaturase", "gene_name": "SCD", "organism": "Bovine", "refseq_name": "stearoyl-CoA desaturase", "refseq_ac": "NP_776384", "gene_names_uniprotkb": "SCD", "gene_names_refseq": "SCD1; SCD", "protein_names_uniprotkb": "Stearoyl-CoA desaturase; 1.14.19.1; Acyl-CoA desaturase; Delta(9)-desaturase; Delta-9 desaturase; Fatty acid desaturase", "protein_names_refseq": "acyl-CoA desaturase; delta(9)-desaturase; fatty acid desaturase; stearoyl-CoA desaturase (delta-9-desaturase); stearoyl-CoA desaturase; stearoyl-coenzyme A desaturase", "tax_id": 9913, "disease": "", "pathway": " (bta:280924); (R-BTA-75105)", "pathway_count": 2, "publication_count": 10, "publication_id_list": "10945276;15834635;16603123;17468887;17582140;27439381;29154485;29274956;31230519;33052678", "class_list": "", "function": "A transcriptional enhancer element in the stearoyl-CoA desaturase promoter was identified and characterized., [RefSeq, PubMed]; Bovine Stearoyl-CoA Desaturase 1 Promotes Adipogenesis by Activating the PPARgamma Receptor., [RefSeq, PubMed]; E. coli mastitis reduced SCD1 expression in liver and udder. Publication Status: Online-Only, [RefSeq, PubMed]; Expression of SCD1 was downregulated through reduced transcription and abundance of the transcription factor sterol regulatory element-binding protein 1 (SREBP1c).This effect was augmented by local chromatin tightening and DNA methylation at and around the SREBP1c binding site in the SCD1 promoter, [RefSeq, PubMed]; In this paper, we describe for the first time a second SCD isoform in cattle, which appears to be an ortholog of human SCD5 rather than a homolog of bovine SCD1 or any of the described murine SCD isoforms, [RefSeq, PubMed]; It plays important roles in growth and lipid metabolisms., [RefSeq, PubMed]; LEP and SCD polymorphisms are associated with milk somatic cell count, electrical conductivity and pH values in Holstein cows., [RefSeq, PubMed]; Sequences of scd promoter of cows producing high milk CLA compared with low CLA showed no polymorphisms in this promoter segment or among scd promoter of Holstein Friesian, Montbeliarde, Normande, Norwegian Red, Charlois, Limousin & Kerry breeds., [RefSeq, PubMed]; Stearoyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates. Catalyzes the insertion of a cis double bond at the delta-9 position into fatty acyl-CoA substrates including palmitoyl-CoA and stearoyl-CoA (By similarity). Gives rise to a mixture of 16:1 and 18:1 unsaturated fatty acids. Plays an important role in lipid biosynthesis. Plays an important role in regulating the expression of genes that are involved in lipogenesis and in regulating mitochondrial fatty acid oxidation (By similarity). Plays an important role in body energy homeostasis (By similarity). Contributes to the biosynthesis of membrane phospholipids, cholesterol esters and triglycerides (By similarity)., [UniProtKB, UniProtKB, UniProtKB]; Study concludes that the higher desaturase activity of SCD allele C in the composition of milk fat can only be appreciated on myristic and caproleic FA because of the different pathways from which milk FA derive, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q861R6;Q8SQ76", "ec_number_list": "1.14.19.1", "go_molecular_function": "GO:0005506 iron ion binding;GO:0004768 stearoyl-CoA 9-desaturase activity;GO:0016491 oxidoreductase activity;GO:0032896 palmitoyl-CoA 9-desaturase activity", "go_cellular_component": "GO:0016020 membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006636 unsaturated fatty acid biosynthetic process;GO:1903966 monounsaturated fatty acid biosynthetic process;GO:0070542 response to fatty acid", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "Q9TT94-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9TT96-1", "uniprot_id": "ADRB1_BOVIN", "mass": 50137.0, "length": 467, "protein_name": "Beta-1 adrenergic receptor", "gene_name": "ADRB1", "organism": "Bovine", "refseq_name": "beta-1 adrenergic receptor", "refseq_ac": "NP_919242", "gene_names_uniprotkb": "ADRB1", "gene_names_refseq": "ADRB1", "protein_names_uniprotkb": "Beta-1 adrenergic receptor; Beta-1 adrenoceptor; Beta-1 adrenoreceptor", "protein_names_refseq": "adrenergic, beta-1-, receptor; beta-1 adrenergic receptor; beta-1 adrenoceptor; beta-1 adrenoreceptor", "tax_id": 9913, "disease": "", "pathway": " (bta:281604)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "12586313;15760672", "class_list": "", "function": "Beta 1,2 and 3-adrenergic receptors in cattle were positively associated with hepatic activities of gluconeogenetic enzymes and with plasma glucose levels, suggesting functional importance, [RefSeq, PubMed]; G protein-coupled receptor for catecholamines that couples to G(s) proteins to activate adenylate cyclase and cAMP-dependent pathway. Binds epinephrine and norepinephrine with approximately equal affinity. Mediates the activation of Ras via binding with cAMP-dependent RAPGEF2. As part of the sympathetic nervous system, plays a role in the physiologic regulation of cardiac functions such as stimulation of cardiomyocyte contraction (By similarity). Also delivers proapoptotic signals in cardiomyocytes (By similarity). Involved in the regulation of sleep/wake behaviors (By similarity)., [UniProtKB, UniProtKB, UniProtKB]; Of the beta-adrenergic receptors, adrenergic beta(2)-receptor type was most highly expressed in the mammary gland of dairy cows followed by beta(1) and beta(3), [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q9TUB4", "ec_number_list": "", "go_molecular_function": "GO:0004940 beta1-adrenergic receptor activity", "go_cellular_component": "GO:0005769 early endosome;GO:0005886 plasma membrane", "go_biological_process": "GO:0045187 regulation of circadian sleep/wake cycle, sleep;GO:0043410 positive regulation of MAPK cascade;GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway;GO:0002025 norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure;GO:0010666 positive regulation of cardiac muscle cell apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q9TT96-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9TTR7-1", "uniprot_id": "COT2_BOVIN", "mass": 45557.0, "length": 414, "protein_name": "COUP transcription factor 2", "gene_name": "NR2F2", "organism": "Bovine", "refseq_name": "COUP transcription factor 2", "refseq_ac": "NP_776827", "gene_names_uniprotkb": "NR2F2; TFCOUP2", "gene_names_refseq": "NR2F2; TFCOUP2", "protein_names_uniprotkb": "COUP transcription factor 2; COUP transcription factor II; COUP-TF II; COUP-TF2; Nuclear receptor subfamily 2 group F member 2", "protein_names_refseq": "COUP transcription factor 2; COUP transcription factor II; COUP-TF II; COUP-TF2; apolipoprotein A1 regulatory protein 1; nuclear receptor subfamily 2, group F, member 1; transcription factor COUP 2", "tax_id": 9913, "disease": "", "pathway": " (bta:281945); (R-BTA-9940951)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "15171724;18409030", "class_list": "", "function": "Involvement of Ad4BP/SF-1, DAX-1, and COUP-TFII transcription factor on steroid production and luteinization in ovarian theca cells., [RefSeq, PubMed]; Ligand-activated transcription factor. Activated by high concentrations of 9-cis-retinoic acid and all-trans-retinoic acid, but not by dexamethasone, cortisol or progesterone (in vitro). Regulation of the apolipoprotein A-I gene transcription. Binds to DNA site A. May be required to establish ovary identity during early gonad development., [UniProtKB, UniProtKB]; Results show that chicken ovalbumin upstream promoter transcription factor II (COUP-TFII), hepatocyte nuclear factor 4alpha (HNF-4alpha) and HNF-4gamma regulate growth hormone receptor 1A promoter activity by binding to a common DNA element, [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q08DL8", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0042803 protein homodimerization activity;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0004879 nuclear receptor activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0060838 lymphatic endothelial cell fate commitment;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0007399 nervous system development;GO:0030154 cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q9TTR7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9TTS3-1", "uniprot_id": "ACACA_BOVIN", "mass": 265303.0, "length": 2346, "protein_name": "Acetyl-CoA carboxylase 1", "gene_name": "ACACA", "organism": "Bovine", "refseq_name": "acetyl-CoA carboxylase 1", "refseq_ac": "NP_776649", "gene_names_uniprotkb": "ACACA; ACAC; ACCA", "gene_names_refseq": "ACACA; ACC1; ACCA", "protein_names_uniprotkb": "Acetyl-CoA carboxylase 1; 6.4.1.2; ACC-alpha; ACC1", "protein_names_refseq": "ACC-alpha; acetyl-CoA carboxylase 1; acetyl-coenzyme A carboxylase alpha", "tax_id": 9913, "disease": "", "pathway": " (bta:281590)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "11485560;20002363;22718502;23262334", "class_list": "", "function": "Cytosolic enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the first and rate-limiting step of de novo fatty acid biosynthesis. This is a 2 steps reaction starting with the ATP-dependent carboxylation of the biotin carried by the biotin carboxyl carrier (BCC) domain followed by the transfer of the carboxyl group from carboxylated biotin to acetyl-CoA., [UniProtKB, UniProtKB]; Expression profiles showed that PI is the promoter driving expression of the dominant ACACA-transcript in brain., [RefSeq, PubMed]; Results suggested that the SNPs in the promoter I region of ACACA gene are associated with variations in the fatty acid contents in longissimus dorsi muscle., [RefSeq, PubMed]; Since the promoter region, PIII, is specific to mammary gland during lactation, the altered expression of the ACACA gene owing to the SNPs in the PIII region may influence the fatty acid composition in the milk., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 21, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "6.4.1.2", "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0003989 acetyl-CoA carboxylase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005829 cytosol", "go_biological_process": "GO:0051289 protein homotetramerization;GO:0006084 acetyl-CoA metabolic process;GO:0006633 fatty acid biosynthetic process;GO:2001295 malonyl-CoA biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q9TTS3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9TUM6-1", "uniprot_id": "PLIN2_BOVIN", "mass": 49368.0, "length": 450, "protein_name": "Perilipin-2", "gene_name": "PLIN2", "organism": "Bovine", "refseq_name": "perilipin-2", "refseq_ac": "NP_776405", "gene_names_uniprotkb": "PLIN2; ADFP; ADRP", "gene_names_refseq": "ADFP; PLIN2", "protein_names_uniprotkb": "Perilipin-2; ADRP; Adipophilin; Adipose differentiation-related protein", "protein_names_refseq": "ADRP; adipophilin; adipose differentiation-related protein; perilipin-2", "tax_id": 9913, "disease": "", "pathway": " (bta:280981)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "10629799;18393390;19712591;24560670", "class_list": "", "function": "25 novel polymorphisms were identified within all exons and their flanking regions of ADFP, including the promoter region., [RefSeq, PubMed]; Adipophilin and TIP47 are expressed in lipid droplets of vitamin A-storing hepatic stellate cells and additionally in lipid droplets of steatotic hepatocytes., [RefSeq, PubMed]; Structural component of lipid droplets, which is required for the formation and maintenance of lipid storage droplets., [UniProtKB, UniProtKB]; These results demonstrate that bovine embryos at the blastocyst stage expressed ADRP mRNA and protein, and that the embryonic culture system modified this expression., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q3T0Y0", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005811 lipid droplet;GO:0005829 cytosol;GO:0016020 membrane", "go_biological_process": "GO:0042149 cellular response to glucose starvation;GO:0010890 positive regulation of triglyceride storage;GO:0019915 lipid storage;GO:1905691 lipid droplet disassembly", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q9TUM6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KJ33-1", "uniprot_id": "LIMS2_BOVIN", "mass": 38895.0, "length": 341, "protein_name": "LIM and senescent cell antigen-like-containing domain protein 2", "gene_name": "LIMS2", "organism": "Bovine", "refseq_name": "LIM and senescent cell antigen-like-containing domain protein 2", "refseq_ac": "NP_001124223", "gene_names_uniprotkb": "LIMS2; PINCH2", "gene_names_refseq": "LIMS1; LIMS2", "protein_names_uniprotkb": "LIM and senescent cell antigen-like-containing domain protein 2; PINCH-2; Particularly interesting new Cys-His protein 2", "protein_names_refseq": "LIM and senescent cell antigen-like domains 1; LIM and senescent cell antigen-like domains 2; LIM and senescent cell antigen-like-containing domain protein 2; PINCH-2; particularly interesting new Cys-His protein 2", "tax_id": 9913, "disease": "", "pathway": " (bta:515401); (R-BTA-446343); (R-BTA-446353)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Adapter protein in a cytoplasmic complex linking beta-integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0046872 metal ion binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0005911 cell-cell junction;GO:0005925 focal adhesion", "go_biological_process": "GO:0098609 cell-cell adhesion;GO:2001046 positive regulation of integrin-mediated signaling pathway;GO:0045216 cell-cell junction organization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2KJ33-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q1JPB0-1", "uniprot_id": "ILEU_BOVIN", "mass": 42236.0, "length": 377, "protein_name": "Leukocyte elastase inhibitor", "gene_name": "SERPINB1", "organism": "Bovine", "refseq_name": "leukocyte elastase inhibitor", "refseq_ac": "NP_001193539", "gene_names_uniprotkb": "SERPINB1", "gene_names_refseq": "LEI; SERPINB1", "protein_names_uniprotkb": "Leukocyte elastase inhibitor; LEI; Serpin B1", "protein_names_refseq": "leukocyte elastase inhibitor pseudogene; leukocyte elastase inhibitor; serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 1; serpin B1; serpin peptidase inhibitor, clade B (ovalbumin), member 1", "tax_id": 9913, "disease": "", "pathway": " (bta:507264); (R-BTA-6798695); (R-BTA-9948001)", "pathway_count": 3, "publication_count": 2, "publication_id_list": "16305752;26085342", "class_list": "", "function": "Neutrophil serine protease inhibitor that plays an essential role in the regulation of the innate immune response, inflammation and cellular homeostasis. Acts primarily to protect the cell from proteases released in the cytoplasm during stress or infection. These proteases are important in killing microbes but when released from granules, these potent enzymes also destroy host proteins and contribute to mortality. Regulates the activity of the neutrophil proteases elastase, cathepsin G, proteinase-3, chymase, chymotrypsin, and kallikrein-3. Also acts as a potent intracellular inhibitor of GZMH by directly blocking its proteolytic activity. During inflammation, limits the activity of inflammatory caspases CASP1, CASP4 and CASP5 by suppressing their caspase-recruitment domain (CARD) oligomerization and enzymatic activation. When secreted, promotes the proliferation of beta-cells via its protease inhibitory function., [UniProtKB, UniProtKB]; The function of LEI during wound healing is related to its activity as a protease inhibitor and/or to its anti-apoptotic activity., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004867 serine-type endopeptidase inhibitor activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005769 early endosome;GO:0044194 cytolytic granule;GO:0036464 cytoplasmic ribonucleoprotein granule;GO:0005737 cytoplasm", "go_biological_process": "GO:0032691 negative regulation of interleukin-1 beta production;GO:0030336 negative regulation of cell migration;GO:0044342 type B pancreatic cell proliferation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q1JPB0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q17QN9-1", "uniprot_id": "S22AG_BOVIN", "mass": 64355.0, "length": 572, "protein_name": "Solute carrier family 22 member 16", "gene_name": "SLC22A16", "organism": "Bovine", "refseq_name": "solute carrier family 22 member 16", "refseq_ac": "NP_001069792", "gene_names_uniprotkb": "SLC22A16", "gene_names_refseq": "SLC22A16", "protein_names_uniprotkb": "Solute carrier family 22 member 16; CT2; Carnitine transporter 2", "protein_names_refseq": "CT2; carnitine transporter 2; solute carrier family 22 member 16", "tax_id": 9913, "disease": "", "pathway": " (bta:614380); (R-BTA-549127)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Facilitative organic cation transporter that mediates the transport of carnitine as well as the polyamine spermidine. Mediates the partially Na(+)-dependent bidirectional transport of carnitine. May mediate L-carnitine secretion from testis epididymal epithelium into the lumen which is involved in the maturation of spermatozoa., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0022857 transmembrane transporter activity;GO:0005275 amine transmembrane transporter activity;GO:0015226 carnitine transmembrane transporter activity;GO:0015606 spermidine transmembrane transporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane;GO:0012505 endomembrane system", "go_biological_process": "GO:0046717 acid secretion;GO:0015695 organic cation transport;GO:0006811 monoatomic ion transport;GO:0007283 spermatogenesis;GO:0030154 cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q17QN9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2M2T6-1", "uniprot_id": "ASTER_BOVIN", "mass": 12038.0, "length": 106, "protein_name": "PAT complex subunit Asterix", "gene_name": "WDR83OS", "organism": "Bovine", "refseq_name": "PAT complex subunit Asterix", "refseq_ac": "NP_001039475", "gene_names_uniprotkb": "WDR83OS", "gene_names_refseq": "C19orf56; C7H19orf56; PAT-10; PAT10; WDR83OS", "protein_names_uniprotkb": "PAT complex subunit Asterix; PAT-10; PAT10; Protein WDR83OS homolog; Protein associated with the ER translocon of 10kDa", "protein_names_refseq": "PAT complex subunit Asterix; UPF0139 membrane protein C19orf56 homolog; protein Asterix; protein WDR83OS homolog; protein associated with the ER translocon of 10kDa", "tax_id": 9913, "disease": "", "pathway": " (bta:508733)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of the multi-pass translocon (MPT) complex that mediates insertion of multi-pass membrane proteins into the lipid bilayer of membranes. The MPT complex takes over after the SEC61 complex: following membrane insertion of the first few transmembrane segments of proteins by the SEC61 complex, the MPT complex occludes the lateral gate of the SEC61 complex to promote insertion of subsequent transmembrane regions (By similarity). Within the MPT complex, the PAT subcomplex sequesters any highly polar regions in the transmembrane domains away from the non-polar membrane environment until they can be buried in the interior of the fully assembled protein. Within the PAT subcomplex, WDR83OS/Asterix binds to and redirects the substrate to a location behind the SEC61 complex (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0044183 protein folding chaperone", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane;GO:0160064 multi-pass translocon complex", "go_biological_process": "GO:0045048 protein insertion into ER membrane;GO:0160063 multi-pass transmembrane protein insertion into ER membrane", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2M2T6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q29RN8-1", "uniprot_id": "SE6L2_BOVIN", "mass": 97508.0, "length": 910, "protein_name": "Seizure 6-like protein 2", "gene_name": "SEZ6L2", "organism": "Bovine", "refseq_name": "seizure 6-like protein 2 precursor", "refseq_ac": "NP_001039392", "gene_names_uniprotkb": "SEZ6L2", "gene_names_refseq": "SEZ6L2", "protein_names_uniprotkb": "Seizure 6-like protein 2", "protein_names_refseq": "seizure 6-like protein 2 precursor; seizure 6-like protein 2", "tax_id": 9913, "disease": "", "pathway": " (bta:505735)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "May contribute to specialized endoplasmic reticulum functions in neurons., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 11, "predicted_n_glycosites": 9, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 11, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005886 plasma membrane;GO:0043025 neuronal cell body;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0008344 adult locomotory behavior;GO:0021680 cerebellar Purkinje cell layer development;GO:0060074 synapse maturation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q29RN8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KJE0-1", "uniprot_id": "TAXB1_BOVIN", "mass": 94059.0, "length": 817, "protein_name": "Tax1-binding protein 1 homolog", "gene_name": "TAX1BP1", "organism": "Bovine", "refseq_name": "tax1-binding protein 1 homolog", "refseq_ac": "NP_001039874", "gene_names_uniprotkb": "TAX1BP1", "gene_names_refseq": "TAX1BP1", "protein_names_uniprotkb": "Tax1-binding protein 1 homolog", "protein_names_refseq": "Tax1 (human T-cell leukemia virus type I) binding protein 1; tax1-binding protein 1 homolog", "tax_id": 9913, "disease": "", "pathway": " (bta:535589); (R-BTA-5357905); (R-BTA-936440)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Ubiquitin-binding adapter that participates in inflammatory, antiviral and innate immune processes as well as selective autophagy regulation. Plays a key role in the negative regulation of NF-kappa-B and IRF3 signalings by acting as an adapter for the ubiquitin-editing enzyme A20/TNFAIP3 to bind and inactivate its substrates. Disrupts the interactions between the E3 ubiquitin ligase TRAF3 and TBK1/IKBKE to attenuate 'Lys63'-linked polyubiquitination of TBK1 and thereby IFN-beta production. Also recruits A20/TNFAIP3 to ubiquitinated signaling proteins TRAF6 and RIPK1, leading to their deubiquitination and disruption of IL-1 and TNF-induced NF-kappa-B signaling pathways. Inhibits virus-induced apoptosis by inducing the 'Lys-48'-linked polyubiquitination and degradation of MAVS via recruitment of the E3 ligase ITCH, thereby attenuating MAVS-mediated apoptosis signaling. As a macroautophagy/autophagy receptor, facilitates the xenophagic clearance of pathogenic bacteria such as Salmonella typhimurium and Mycobacterium tuberculosis. Upon NBR1 recruitment to the SQSTM1-ubiquitin condensates, acts as the major recruiter of RB1CC1 to these ubiquitin condensates to promote their autophagic degradation., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0019900 kinase binding;GO:0035591 signaling adaptor activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0031410 cytoplasmic vesicle;GO:0005776 autophagosome;GO:0000407 phagophore assembly site", "go_biological_process": "GO:2000660 negative regulation of interleukin-1-mediated signaling pathway;GO:0043066 negative regulation of apoptotic process;GO:0006915 apoptotic process;GO:0043124 negative regulation of canonical NF-kappaB signal transduction;GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2KJE0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q17QJ7-1", "uniprot_id": "P5CR2_BOVIN", "mass": 33630.0, "length": 320, "protein_name": "Pyrroline-5-carboxylate reductase 2", "gene_name": "PYCR2", "organism": "Bovine", "refseq_name": "pyrroline-5-carboxylate reductase 2", "refseq_ac": "NP_001068649", "gene_names_uniprotkb": "PYCR2", "gene_names_refseq": "PYCR2", "protein_names_uniprotkb": "Pyrroline-5-carboxylate reductase 2; 1.5.1.2; P5C reductase 2; P5CR 2", "protein_names_refseq": "P5C reductase 2; P5CR 2; pyrroline-5-carboxylate reductase 2; pyrroline-5-carboxylate reductase family member 2", "tax_id": 9913, "disease": "", "pathway": " (bta:504987); (R-BTA-8964539)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Oxidoreductase that catalyzes the last step in proline biosynthesis, which corresponds to the reduction of pyrroline-5-carboxylate to L-proline using NAD(P)H. At physiologic concentrations, has higher specific activity in the presence of NADH. Involved in cellular response to oxidative stress. In some cell types, such as erythrocytes, its primary function may be the generation of NADP(+)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.5.1.2", "go_molecular_function": "GO:0004735 pyrroline-5-carboxylate reductase activity", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0034599 cellular response to oxidative stress;GO:0055129 L-proline biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q17QJ7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KIY6-1", "uniprot_id": "HORM1_BOVIN", "mass": 44785.0, "length": 393, "protein_name": "HORMA domain-containing protein 1", "gene_name": "HORMAD1", "organism": "Bovine", "refseq_name": "HORMA domain-containing protein 1", "refseq_ac": "NP_001039770", "gene_names_uniprotkb": "HORMAD1", "gene_names_refseq": "HORMAD1", "protein_names_uniprotkb": "HORMA domain-containing protein 1", "protein_names_refseq": "HORMA domain-containing protein 1", "tax_id": 9913, "disease": "", "pathway": " (bta:529615)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Plays a key role in meiotic progression. Regulates 3 different functions during meiosis: ensures that sufficient numbers of processed DNA double-strand breaks (DSBs) are available for successful homology search by increasing the steady-state numbers of single-stranded DSB ends. Promotes synaptonemal-complex formation independently of its role in homology search. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process believed to form the basis of meiotic silencing of unsynapsed chromatin (MSUC) and meiotic prophase quality control in both sexes., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005694 chromosome;GO:0000795 synaptonemal complex", "go_biological_process": "GO:0051598 meiotic recombination checkpoint signaling;GO:0060629 regulation of homologous chromosome segregation;GO:0007283 spermatogenesis;GO:0007130 synaptonemal complex assembly;GO:0048477 oogenesis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2KIY6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KHW7-1", "uniprot_id": "RGS10_BOVIN", "mass": 21195.0, "length": 181, "protein_name": "Regulator of G protein signaling 10", "gene_name": "RGS10", "organism": "Bovine", "refseq_name": "regulator of G-protein signaling 10", "refseq_ac": "NP_001040005", "gene_names_uniprotkb": "RGS10", "gene_names_refseq": "RGS10", "protein_names_uniprotkb": "Regulator of G protein signaling 10; RGS10", "protein_names_refseq": "regulator of G-protein signaling 10", "tax_id": 9913, "disease": "", "pathway": " (bta:614550)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Regulates G protein-coupled receptor signaling cascades, including signaling downstream of the muscarinic acetylcholine receptor CHRM2. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. Modulates the activity of potassium channels that are activated in response to CHRM2 signaling. Activity on GNAZ is inhibited by palmitoylation of the G protein., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005096 GTPase activator activity;GO:0001965 G-protein alpha-subunit binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0045202 synapse;GO:0016604 nuclear body", "go_biological_process": "GO:0007213 G protein-coupled acetylcholine receptor signaling pathway;GO:0043547 positive regulation of GTPase activity;GO:0009968 negative regulation of signal transduction;GO:0008277 regulation of G protein-coupled receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2KHW7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q1LZF1-1", "uniprot_id": "PAX6_BOVIN", "mass": 46653.0, "length": 422, "protein_name": "Paired box protein Pax-6", "gene_name": "PAX6", "organism": "Bovine", "refseq_name": "paired box protein Pax-6", "refseq_ac": "NP_001035735", "gene_names_uniprotkb": "PAX6", "gene_names_refseq": "PAX6; pax-6", "protein_names_uniprotkb": "Paired box protein Pax-6; Oculorhombin", "protein_names_refseq": "oculorhombin; paired box gene 6 (aniridia, keratitis); paired box protein Pax-6", "tax_id": 9913, "disease": "", "pathway": " (bta:286857)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "24072657;31520776", "class_list": "", "function": "Some polymorphisms in PAX6 are associated with growth traits at some ages, and may be used as candidates for marker-assisted selection in beef cattle breeding program., [RefSeq, PubMed]; This study indicated that g.-931G>T at RPL8 promoter altered its expression by affecting the interplay between Pax6 and RPL8, which may account for the association with milk fat traits. Findings herein first elucidated the biological function of RPL8 gene in milk fat and the identified SNP g.-931G>T may be considered as genetic makers for breeding in dairy cattle., [RefSeq, PubMed]; Transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Required for the differentiation of pancreatic islet alpha cells. Competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters. Regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains (By similarity). Acts as a transcriptional repressor of NFATC1-mediated gene expression (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0000976 transcription cis-regulatory region binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0004842 ubiquitin-protein transferase activity;GO:0070410 co-SMAD binding", "go_cellular_component": "GO:0005634 nucleus;GO:0000785 chromatin;GO:0005654 nucleoplasm;GO:0005737 cytoplasm", "go_biological_process": "GO:0003322 pancreatic A cell development;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0010628 positive regulation of gene expression", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q1LZF1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q17R07-1", "uniprot_id": "ARFG3_BOVIN", "mass": 56766.0, "length": 517, "protein_name": "ADP-ribosylation factor GTPase-activating protein 3", "gene_name": "ARFGAP3", "organism": "Bovine", "refseq_name": "ADP-ribosylation factor GTPase-activating protein 3", "refseq_ac": "NP_001069442", "gene_names_uniprotkb": "ARFGAP3", "gene_names_refseq": "ARFGAP3", "protein_names_uniprotkb": "ADP-ribosylation factor GTPase-activating protein 3; ARF GAP 3", "protein_names_refseq": "ADP-ribosylation factor GTPase-activating protein 3; ARF GAP 3", "tax_id": 9913, "disease": "", "pathway": " (bta:532778); (R-BTA-6807878); (R-BTA-6811434); (R-BTA-9013408)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "1910037", "class_list": "", "function": "GTPase-activating protein (GAP) for ADP ribosylation factor 1 (ARF1) (PubMed:1910037). Hydrolysis of ARF1-bound GTP may lead to dissociation of coatomer from Golgi-derived membranes to allow fusion with target membranes (By similarity)., [UniProtKB, UniProtKB, PubMed]; GTPase-activating protein (GAP) for ADP ribosylation factor 1 (ARF1). Hydrolysis of ARF1-bound GTP may lead to dissociation of coatomer from Golgi-derived membranes to allow fusion with target membranes., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 10, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005096 GTPase activator activity;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005829 cytosol", "go_biological_process": "GO:0048205 COPI coating of Golgi vesicle;GO:0015031 protein transport;GO:0016192 vesicle-mediated transport;GO:0009306 protein secretion", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q17R07-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q17QJ1-1", "uniprot_id": "ACSF2_BOVIN", "mass": 68201.0, "length": 615, "protein_name": "Medium-chain acyl-CoA ligase ACSF2, mitochondrial", "gene_name": "ACSF2", "organism": "Bovine", "refseq_name": "medium-chain acyl-CoA ligase ACSF2, mitochondrial precursor", "refseq_ac": "NP_001071580", "gene_names_uniprotkb": "ACSF2", "gene_names_refseq": "ACSF2", "protein_names_uniprotkb": "Medium-chain acyl-CoA ligase ACSF2, mitochondrial; 6.2.1.2", "protein_names_refseq": "acyl-CoA synthetase family member 2, mitochondrial; medium-chain acyl-CoA ligase ACSF2, mitochondrial precursor; medium-chain acyl-CoA ligase ACSF2, mitochondrial", "tax_id": 9913, "disease": "", "pathway": " (bta:768237); (R-BTA-77289)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Acyl-CoA synthases catalyze the initial reaction in fatty acid metabolism, by forming a thioester with CoA. Has some preference toward medium-chain substrates. Plays a role in adipocyte differentiation., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "6.2.1.2;6.2.1.25", "go_molecular_function": "GO:0005524 ATP binding;GO:0031956 medium-chain fatty acid-CoA ligase activity", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0006631 fatty acid metabolic process;GO:0006629 lipid metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q17QJ1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KI13-1", "uniprot_id": "SGSM3_BOVIN", "mass": 85010.0, "length": 747, "protein_name": "Small G protein signaling modulator 3", "gene_name": "SGSM3", "organism": "Bovine", "refseq_name": "small G protein signaling modulator 3", "refseq_ac": "NP_001070013", "gene_names_uniprotkb": "SGSM3; RUTBC3", "gene_names_refseq": "RUTBC3; SGSM3", "protein_names_uniprotkb": "Small G protein signaling modulator 3; RUN and TBC1 domain-containing protein 3", "protein_names_refseq": "RUN and TBC1 domain containing 3; RUN and TBC1 domain-containing protein 3; merlin binding protein; small G protein signaling modulator 3", "tax_id": 9913, "disease": "", "pathway": " (bta:767820)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "GTPase-activating protein (GAP) specific for Rab5 small GTPase for which it accelerates the intrinsic GTP hydrolysis rate, thereby controlling trafficking through the early endocytic pathway. May play a cooperative role in NF2-mediated growth suppression of cells., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005096 GTPase activator activity;GO:0031267 small GTPase binding", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0005829 cytosol;GO:0005921 gap junction", "go_biological_process": "GO:0032483 regulation of Rab protein signal transduction;GO:0032486 Rap protein signal transduction;GO:0030100 regulation of endocytosis;GO:0016197 endosomal transport;GO:0045732 positive regulation of protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2KI13-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q0VCS0-1", "uniprot_id": "PTCRA_BOVIN", "mass": 33670.0, "length": 319, "protein_name": "Pre T-cell antigen receptor alpha", "gene_name": "PTCRA", "organism": "Bovine", "refseq_name": "pre T-cell antigen receptor alpha precursor", "refseq_ac": "NP_001069101", "gene_names_uniprotkb": "PTCRA", "gene_names_refseq": "PTCRA", "protein_names_uniprotkb": "Pre T-cell antigen receptor alpha; pT-alpha-TCR; pT-alpha; pTa", "protein_names_refseq": "pT-alpha-TCR; pT-alpha; pTa; pre T-cell antigen receptor alpha precursor", "tax_id": 9913, "disease": "", "pathway": " (bta:513669)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of the pre-T-cell receptor complex (composed of PTCRA, TCRB and the CD3 complex) that has a crucial role in early T-cell development, particularly alpha-beta T cell differentiation., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0070244 negative regulation of thymocyte apoptotic process;GO:0046632 alpha-beta T cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q0VCS0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q17QZ3-1", "uniprot_id": "SPX3_BOVIN", "mass": 54430.0, "length": 495, "protein_name": "Sugar phosphate exchanger 3", "gene_name": "SLC37A3", "organism": "Bovine", "refseq_name": "sugar phosphate exchanger 3", "refseq_ac": "NP_001068752", "gene_names_uniprotkb": "SLC37A3; SPX3", "gene_names_refseq": "SLC37A3", "protein_names_uniprotkb": "Sugar phosphate exchanger 3; Solute carrier family 37 member 3", "protein_names_refseq": "solute carrier family 37 (glycerol-3-phosphate transporter), member 3; sugar phosphate exchanger 3", "tax_id": 9913, "disease": "", "pathway": " (bta:506910)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Unlike the other SLC37 members, lacks glucose-6-phosphate antiporter activity. In osteoclasts, forms a transporter complex with ATRAID for nitrogen-containing-bisphophonates (N-BPs) required for releasing N-BP molecules that have trafficked to lysosomes through fluid-phase endocytosis into the cytosol., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0042910 xenobiotic transmembrane transporter activity;GO:0022857 transmembrane transporter activity", "go_cellular_component": "GO:0005765 lysosomal membrane;GO:0005789 endoplasmic reticulum membrane;GO:0031090 organelle membrane", "go_biological_process": "GO:0006855 xenobiotic transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q17QZ3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KJ16-1", "uniprot_id": "PHKG2_BOVIN", "mass": 46542.0, "length": 406, "protein_name": "Phosphorylase b kinase gamma catalytic chain, liver/testis isoform", "gene_name": "PHKG2", "organism": "Bovine", "refseq_name": "phosphorylase b kinase gamma catalytic chain, liver/testis isoform", "refseq_ac": "NP_001039593", "gene_names_uniprotkb": "PHKG2", "gene_names_refseq": "PHKG2", "protein_names_uniprotkb": "Phosphorylase b kinase gamma catalytic chain, liver/testis isoform; 2.7.11.19; PHK-gamma-LT; PHK-gamma-T; Phosphorylase kinase subunit gamma-2", "protein_names_refseq": "PHK-gamma-LT; PHK-gamma-T; phosphorylase b kinase gamma catalytic chain, liver/testis isoform; phosphorylase kinase subunit gamma-2; phosphorylase kinase, gamma 2 (testis); serine/threonine-protein kinase PHKG2", "tax_id": 9913, "disease": "", "pathway": " (bta:512670); (R-BTA-70221)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "Catalytic subunit of the phosphorylase b kinase (PHK), which mediates the neural and hormonal regulation of glycogen breakdown (glycogenolysis) by phosphorylating and thereby activating glycogen phosphorylase. May regulate glycogeneolysis in the testis. In vitro, phosphorylates PYGM., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A7E3T5", "ec_number_list": "2.4.1.1;2.7.11.19", "go_molecular_function": "GO:0004689 phosphorylase kinase activity;GO:0005516 calmodulin binding;GO:0005524 ATP binding", "go_cellular_component": "GO:0005964 phosphorylase kinase complex;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0007165 signal transduction;GO:0005977 glycogen metabolic process;GO:0005980 glycogen catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q2KJ16-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KIH7-1", "uniprot_id": "PH4H_BOVIN", "mass": 51727.0, "length": 451, "protein_name": "Phenylalanine-4-hydroxylase", "gene_name": "PAH", "organism": "Bovine", "refseq_name": "phenylalanine-4-hydroxylase", "refseq_ac": "NP_001039523", "gene_names_uniprotkb": "PAH", "gene_names_refseq": "PAH", "protein_names_uniprotkb": "Phenylalanine-4-hydroxylase; 1.14.16.1; PAH; Phe-4-monooxygenase", "protein_names_refseq": "phe-4-monooxygenase; phenylalanine-4-hydroxylase", "tax_id": 9913, "disease": "", "pathway": " (bta:510583); (R-BTA-8964208)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "12655554;16305752", "class_list": "", "function": "Catalyzes the hydroxylation of L-phenylalanine to L-tyrosine., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Non-responsiveness to 20 mg/kg BH4 was observed in a single patient who was compound heterozygous for the novel mutation R176P (c.527G>C) and the common nullmutation P281L., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A5D9G6", "ec_number_list": "1.14.16.1", "go_molecular_function": "GO:0005506 iron ion binding;GO:0004505 phenylalanine 4-monooxygenase activity", "go_cellular_component": "", "go_biological_process": "GO:0006571 tyrosine biosynthetic process;GO:0006559 L-phenylalanine catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q2KIH7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KJ84-1", "uniprot_id": "TMED5_BOVIN", "mass": 25875.0, "length": 226, "protein_name": "Transmembrane emp24 domain-containing protein 5", "gene_name": "TMED5", "organism": "Bovine", "refseq_name": "transmembrane emp24 domain-containing protein 5 precursor", "refseq_ac": "NP_001039842", "gene_names_uniprotkb": "TMED5", "gene_names_refseq": "TMED5", "protein_names_uniprotkb": "Transmembrane emp24 domain-containing protein 5; p24 family protein gamma 2; p24gamma2", "protein_names_refseq": "p24 family protein gamma 2; p24gamma2; transmembrane emp24 domain-containing protein 5 precursor; transmembrane emp24 domain-containing protein 5; transmembrane emp24 protein transport domain containing 5", "tax_id": 9913, "disease": "", "pathway": " (bta:534351); (R-BTA-3238698)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "Potential role in vesicular protein trafficking, mainly in the early secretory pathway. Required for the maintenance of the Golgi apparatus; involved in protein exchange between Golgi stacks during assembly. Probably not required for COPI-vesicle-mediated retrograde transport (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A5D9A9", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0030134 COPII-coated ER to Golgi transport vesicle;GO:0005789 endoplasmic reticulum membrane;GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0090161 Golgi ribbon formation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q2KJ84-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KI62-1", "uniprot_id": "PTCD3_BOVIN", "mass": 77831.0, "length": 688, "protein_name": "Small ribosomal subunit protein mS39", "gene_name": "PTCD3", "organism": "Bovine", "refseq_name": "small ribosomal subunit protein mS39 precursor", "refseq_ac": "NP_001039499", "gene_names_uniprotkb": "PTCD3; MRPS39", "gene_names_refseq": "MRP-S39; PTCD3", "protein_names_uniprotkb": "Small ribosomal subunit protein mS39; 28S ribosomal protein S39, mitochondrial; MRP-S39; Pentatricopeptide repeat domain-containing protein 3, mitochondrial", "protein_names_refseq": "28S ribosomal protein S39, mitochondrial; pentatricopeptide repeat domain-containing protein 3, mitochondrial; pentatricopeptide repeat-containing protein 3, mitochondrial; small ribosomal subunit protein mS39 precursor; small ribosomal subunit protein mS39", "tax_id": 9913, "disease": "", "pathway": " (bta:509502); (R-BTA-5389840); (R-BTA-5419276); (R-BTA-9937383)", "pathway_count": 4, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Mitochondrial RNA-binding protein that has a role in mitochondrial translation., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0043024 ribosomal small subunit binding;GO:0019843 rRNA binding", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane;GO:0005840 ribosome;GO:1990904 ribonucleoprotein complex;GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0006417 regulation of translation;GO:0032543 mitochondrial translation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2KI62-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q17QQ5-1", "uniprot_id": "G137A_BOVIN", "mass": 43596.0, "length": 395, "protein_name": "Integral membrane protein GPR137", "gene_name": "GPR137", "organism": "Bovine", "refseq_name": "integral membrane protein GPR137", "refseq_ac": "NP_001106766", "gene_names_uniprotkb": "GPR137", "gene_names_refseq": "GPR137", "protein_names_uniprotkb": "Integral membrane protein GPR137", "protein_names_refseq": "integral membrane protein GPR137", "tax_id": 9913, "disease": "", "pathway": " (bta:505015)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Lysosomal integral membrane protein that may regulate MTORC1 complex translocation to lysosomes. May play a role in autophagy., [UniProtKB, UniProtKB]; May activate Wnt/beta-catenin signaling to modulate epithelial cell function., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005765 lysosomal membrane", "go_biological_process": "GO:1904263 positive regulation of TORC1 signaling;GO:0045124 regulation of bone resorption;GO:0010506 regulation of autophagy;GO:0006914 autophagy;GO:0030278 regulation of ossification", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q17QQ5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q29RS8-1", "uniprot_id": "FLI1_BOVIN", "mass": 50865.0, "length": 452, "protein_name": "Friend leukemia integration 1 transcription factor", "gene_name": "FLI1", "organism": "Bovine", "refseq_name": "Friend leukemia integration 1 transcription factor", "refseq_ac": "NP_001039763", "gene_names_uniprotkb": "FLI1", "gene_names_refseq": "FLI1", "protein_names_uniprotkb": "Friend leukemia integration 1 transcription factor; Proto-oncogene Fli-1", "protein_names_refseq": "Friend leukemia integration 1 transcription factor; Friend leukemia virus integration 1; proto-oncogene Fli-1", "tax_id": 9913, "disease": "", "pathway": " (bta:529124)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Sequence-specific transcriptional activator. Recognizes the DNA sequence 5'-C[CA]GGAAGT-3' (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0043565 sequence-specific DNA binding;GO:0003700 DNA-binding transcription factor activity;GO:0003682 chromatin binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0016604 nuclear body", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0030154 cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q29RS8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q1JP75-1", "uniprot_id": "DCXR_BOVIN", "mass": 25650.0, "length": 244, "protein_name": "L-xylulose reductase", "gene_name": "DCXR; LOC112441469", "organism": "Bovine", "refseq_name": "L-xylulose reductase", "refseq_ac": "NP_001069359", "gene_names_uniprotkb": "DCXR; LOC112441469", "gene_names_refseq": "DCXR", "protein_names_uniprotkb": "L-xylulose reductase; 1.1.1.10; DCXR; Dicarbonyl/L-xylulose reductase; XR", "protein_names_refseq": "L-xylulose reductase; XR; dicarbonyl/L-xylulose reductase", "tax_id": 9913, "disease": "", "pathway": " (bta:526937); (R-BTA-5661270)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "16305752;25815750", "class_list": "", "function": "Catalyzes the NADPH-dependent reduction of several pentoses, tetroses, trioses, alpha-dicarbonyl compounds and L-xylulose (By similarity). Can use both NAD and NADP as cosubstrate but shows higher activity with NADP (By similarity). Participates in the uronate cycle of glucose metabolism (By similarity). May play a role in the water absorption and cellular osmoregulation in the proximal renal tubules by producing xylitol, an osmolyte, thereby preventing osmolytic stress from occurring in the renal tubules (By similarity)., [UniProtKB, UniProtKB]; Data describe DCXR in the bovine epididymis and reveal that its behavior differs from that found in humans. The protein is highly expressed and shows a unique pattern of expression in the male tract. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.1.1.10", "go_molecular_function": "GO:0050038 L-xylulose reductase (NADPH) activity;GO:0004090 carbonyl reductase (NADPH) activity;GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor", "go_cellular_component": "GO:0016324 apical plasma membrane;GO:0001669 acrosomal vesicle;GO:0005881 cytoplasmic microtubule;GO:0016020 membrane", "go_biological_process": "GO:0005997 xylulose metabolic process;GO:0042732 D-xylose metabolic process;GO:0006006 glucose metabolic process;GO:0044281 small molecule metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q1JP75-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q1JQ98-1", "uniprot_id": "AP1S1_BOVIN", "mass": 18602.0, "length": 157, "protein_name": "AP-1 complex subunit sigma-1A", "gene_name": "AP1S1", "organism": "Bovine", "refseq_name": "AP-1 complex subunit sigma-1A", "refseq_ac": "NP_001070578", "gene_names_uniprotkb": "AP1S1", "gene_names_refseq": "AP1S1", "protein_names_uniprotkb": "AP-1 complex subunit sigma-1A; Adaptor protein complex AP-1 subunit sigma-1A; Adaptor-related protein complex 1 subunit sigma-1A; Clathrin assembly protein complex 1 sigma-1A small chain; Clathrin coat assembly protein AP19; Golgi adaptor HA1/AP1 adaptin sigma-1A subunit; HA1 19 kDa subunit; Sigma 1a subunit of AP-1 clathrin; Sigma-adaptin 1A; Sigma1A-adaptin", "protein_names_refseq": "AP-1 complex subunit sigma-1A; HA1 19 kDa subunit; adapter-related protein complex 1 sigma-1A subunit; adapter-related protein complex 1 subunit sigma-1A; adaptor protein complex AP-1 sigma-1A subunit; adaptor protein complex AP-1 subunit sigma-1A; adaptor related protein complex 1 sigma 1 subunit; adaptor-related protein complex 1 subunit sigma-1A; clathrin assembly protein complex 1 sigma-1A small chain; clathrin coat assembly protein AP19; golgi adaptor HA1/AP1 adaptin sigma-1A subunit; sigma 1a subunit of AP-1 clathrin; sigma-adaptin 1A; sigma1A-adaptin", "tax_id": 9913, "disease": "", "pathway": " (bta:768053); (R-BTA-2132295); (R-BTA-432720); (R-BTA-432722)", "pathway_count": 4, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0035615 clathrin adaptor activity", "go_cellular_component": "GO:0005905 clathrin-coated pit;GO:0030121 AP-1 adaptor complex;GO:0043195 terminal bouton", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0016192 vesicle-mediated transport;GO:0009615 response to virus", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q1JQ98-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q1RMI8-1", "uniprot_id": "CCD22_BOVIN", "mass": 67042.0, "length": 595, "protein_name": "Coiled-coil domain-containing protein 22", "gene_name": "CCDC22", "organism": "Bovine", "refseq_name": "coiled-coil domain-containing protein 22", "refseq_ac": "NP_001069484", "gene_names_uniprotkb": "CCDC22", "gene_names_refseq": "CCDC22", "protein_names_uniprotkb": "Coiled-coil domain-containing protein 22", "protein_names_refseq": "coiled-coil domain-containing protein 22", "tax_id": 9913, "disease": "", "pathway": " (bta:534246); (R-BTA-8951664)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of the commander complex that is essential for endosomal recycling of transmembrane cargos; the Commander complex is composed of composed of the CCC subcomplex and the retriever subcomplex (By similarity). Component of the CCC complex, which is involved in the regulation of endosomal recycling of surface proteins, including integrins, signaling receptor and channels (By similarity). Involved in regulation of NF-kappa-B signaling (By similarity). Promotes ubiquitination of I-kappa-B-kinase subunit IKBKB and its subsequent proteasomal degradation leading to NF-kappa-B activation; the function may involve association with COMMD8 and a CUL1-dependent E3 ubiquitin ligase complex (By similarity). May down-regulate NF-kappa-B activity via association with COMMD1 and involving a CUL2-dependent E3 ubiquitin ligase complex. Regulates the cellular localization of COMM domain-containing proteins, such as COMMD1 and COMMD10 (By similarity). Component of the CCC complex, which is involved in the regulation of endosomal recycling of surface proteins, including integrins, signaling receptor and channels. The CCC complex associates with SNX17, retriever and WASH complexes to prevent lysosomal degradation and promote cell surface recycling of numerous cargos such as integrins ITGA5:ITGB1 (By similarity). Plays a role in copper ion homeostasis (By similarity). Involved in copper-dependent ATP7A trafficking between the trans-Golgi network and vesicles in the cell periphery; the function is proposed to depend on its association within the CCC complex and cooperation with the WASH complex on early endosomes (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0097602 cullin family protein binding", "go_cellular_component": "GO:0005768 endosome;GO:0005813 centrosome;GO:0032991 protein-containing complex", "go_biological_process": "GO:0015031 protein transport;GO:0032456 endocytic recycling;GO:2000060 positive regulation of ubiquitin-dependent protein catabolic process;GO:0006878 intracellular copper ion homeostasis;GO:0043123 positive regulation of canonical NF-kappaB signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q1RMI8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2HJD0-1", "uniprot_id": "FAF2_BOVIN", "mass": 52664.0, "length": 445, "protein_name": "FAS-associated factor 2", "gene_name": "FAF2", "organism": "Bovine", "refseq_name": "FAS-associated factor 2", "refseq_ac": "NP_001070488", "gene_names_uniprotkb": "FAF2; UBXD8", "gene_names_refseq": "FAF2; UBX8; UBXD8", "protein_names_uniprotkb": "FAS-associated factor 2; UBX domain-containing protein 8", "protein_names_refseq": "FAS-associated factor 2; UBX domain containing 8; UBX domain-containing protein 8", "tax_id": 9913, "disease": "", "pathway": " (bta:767948); (R-BTA-6798695); (R-BTA-8980692)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Plays an important role in endoplasmic reticulum-associated degradation (ERAD) that mediates ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins. By controlling the steady-state expression of the IGF1R receptor, indirectly regulates the insulin-like growth factor receptor signaling pathway. Recruits ATPase VCP to lipid droplets and also binds to phospholipase PNPLA2/ATGL, inhibiting PNPLA2 activity by promoting its dissociation from its ABHD5/CGI-58 activator. This inhibits PNPLA2-mediated triacylglycerol hydrolysis and leads to inhibition of lipid droplet degradation. Involved in stress granule disassembly: associates with ubiquitinated G3BP1 in response to heat shock, thereby promoting interaction between ubiquitinated G3BP1 and VCP, followed by G3BP1 extraction from stress granules and stress granule disassembly., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0030674 protein-macromolecule adaptor activity;GO:0043130 ubiquitin binding;GO:0031625 ubiquitin protein ligase binding;GO:0055102 lipase inhibitor activity;GO:0035473 lipase binding", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005811 lipid droplet;GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex", "go_biological_process": "GO:0036503 ERAD pathway;GO:0006986 response to unfolded protein;GO:0035617 stress granule disassembly;GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0030970 retrograde protein transport, ER to cytosol", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2HJD0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2HJD5-1", "uniprot_id": "ECHD1_BOVIN", "mass": 33542.0, "length": 306, "protein_name": "Ethylmalonyl-CoA decarboxylase", "gene_name": "ECHDC1", "organism": "Bovine", "refseq_name": "ethylmalonyl-CoA decarboxylase", "refseq_ac": "NP_001030492", "gene_names_uniprotkb": "ECHDC1", "gene_names_refseq": "ECHDC1; MMCD", "protein_names_uniprotkb": "Ethylmalonyl-CoA decarboxylase; 4.1.1.94; Enoyl-CoA hydratase domain-containing protein 1; MMCD; Methylmalonyl-CoA decarboxylase", "protein_names_refseq": "enoyl CoA hydratase domain containing 1; enoyl Coenzyme A hydratase domain containing 1; enoyl-CoA hydratase domain-containing protein 1; ethylmalonyl-CoA decarboxylase; methylmalonyl-CoA decarboxylase", "tax_id": 9913, "disease": "", "pathway": " (bta:536284)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "16305752;19393038", "class_list": "", "function": "Decarboxylates ethylmalonyl-CoA, a potentially toxic metabolite, to form butyryl-CoA, suggesting it might be involved in metabolite proofreading. Acts preferentially on (S)-ethylmalonyl-CoA but also has some activity on the (R)-isomer. Also has methylmalonyl-CoA decarboxylase activity at lower level., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "F1MDK4;Q58DU9", "ec_number_list": "4.1.1.94", "go_molecular_function": "GO:0004492 methyl/ethyl malonyl-CoA decarboxylase activity;GO:0016831 carboxy-lyase activity;GO:0016829 lyase activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0006635 fatty acid beta-oxidation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q2HJD5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KI69-1", "uniprot_id": "KCIP4_BOVIN", "mass": 28731.0, "length": 250, "protein_name": "Kv channel-interacting protein 4", "gene_name": "KCNIP4", "organism": "Bovine", "refseq_name": "Kv channel-interacting protein 4", "refseq_ac": "NP_001070403", "gene_names_uniprotkb": "KCNIP4", "gene_names_refseq": "KCNIP4", "protein_names_uniprotkb": "Kv channel-interacting protein 4; KChIP4", "protein_names_refseq": "KChIP4; Kv channel interacting protein 4; Kv channel-interacting protein 4; potassium channel-interacting protein 4", "tax_id": 9913, "disease": "", "pathway": " (bta:614299); (R-BTA-5576894)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Regulatory subunit of Kv4/D (Shal)-type voltage-gated rapidly inactivating A-type potassium channels. Modulates KCND2 channel density, inactivation kinetics and rate of recovery from inactivation in a calcium-dependent and isoform-specific manner. Modulates KCND3/Kv4.3 currents. Isoform 4 does not increase KCND2 expression at the cell membrane. Isoform 4 retains KCND3 in the endoplasmic reticulum and negatively regulates its expression at the cell membrane., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0015459 potassium channel regulator activity;GO:0005509 calcium ion binding;GO:0005267 potassium channel activity", "go_cellular_component": "GO:0005777 peroxisome;GO:0008076 voltage-gated potassium channel complex;GO:0005886 plasma membrane;GO:0034702 monoatomic ion channel complex", "go_biological_process": "GO:1901379 regulation of potassium ion transmembrane transport;GO:0009966 regulation of signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2KI69-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KI30-1", "uniprot_id": "REEP2_BOVIN", "mass": 28440.0, "length": 254, "protein_name": "Receptor expression-enhancing protein 2", "gene_name": "REEP2", "organism": "Bovine", "refseq_name": "receptor expression-enhancing protein 2", "refseq_ac": "NP_001039790", "gene_names_uniprotkb": "REEP2", "gene_names_refseq": "REEP2", "protein_names_uniprotkb": "Receptor expression-enhancing protein 2", "protein_names_refseq": "receptor expression-enhancing protein 2", "tax_id": 9913, "disease": "", "pathway": " (bta:532432)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Required for endoplasmic reticulum (ER) network formation, shaping and remodeling. May enhance the cell surface expression of odorant receptors (By similarity)., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008017 microtubule binding;GO:0031883 taste receptor binding", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane;GO:0005881 cytoplasmic microtubule;GO:0071782 endoplasmic reticulum tubular network;GO:0016020 membrane", "go_biological_process": "GO:0071786 endoplasmic reticulum tubular network organization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2KI30-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q17QD6-1", "uniprot_id": "TEFF2_BOVIN", "mass": 41385.0, "length": 374, "protein_name": "Tomoregulin-2", "gene_name": "TMEFF2", "organism": "Bovine", "refseq_name": "tomoregulin-2 precursor", "refseq_ac": "NP_001069569", "gene_names_uniprotkb": "TMEFF2", "gene_names_refseq": "TMEFF2", "protein_names_uniprotkb": "Tomoregulin-2; TR-2; Transmembrane protein with EGF-like and two follistatin-like domains", "protein_names_refseq": "TR-2; tomoregulin-2 precursor; tomoregulin-2; transmembrane protein with EGF-like and two follistatin-like domains", "tax_id": 9913, "disease": "", "pathway": " (bta:538354)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "May be a survival factor for hippocampal and mesencephalic neurons. The shedded form may up-regulate cell proliferation (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005576 extracellular region;GO:0016020 membrane", "go_biological_process": "GO:0030154 cell differentiation;GO:0006950 response to stress", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q17QD6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2HJ56-1", "uniprot_id": "PWP1_BOVIN", "mass": 55865.0, "length": 500, "protein_name": "Periodic tryptophan protein 1 homolog", "gene_name": "PWP1", "organism": "Bovine", "refseq_name": "periodic tryptophan protein 1 homolog", "refseq_ac": "NP_001039631", "gene_names_uniprotkb": "PWP1", "gene_names_refseq": "PWP1", "protein_names_uniprotkb": "Periodic tryptophan protein 1 homolog", "protein_names_refseq": "periodic tryptophan protein 1 homolog", "tax_id": 9913, "disease": "", "pathway": " (bta:514147)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Chromatin-associated factor that regulates transcription (By similarity). Regulates Pol I-mediated rRNA biogenesis and, probably, Pol III-mediated transcription (By similarity). Regulates the epigenetic status of rDNA (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 7, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:1990889 histone H4K20me3 reader activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005730 nucleolus;GO:0005694 chromosome", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006364 rRNA processing;GO:1901838 positive regulation of transcription of nucleolar large rRNA by RNA polymerase I", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2HJ56-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2HJD7-1", "uniprot_id": "3HIDH_BOVIN", "mass": 35410.0, "length": 336, "protein_name": "3-hydroxyisobutyrate dehydrogenase, mitochondrial", "gene_name": "HIBADH", "organism": "Bovine", "refseq_name": "3-hydroxyisobutyrate dehydrogenase, mitochondrial precursor", "refseq_ac": "NP_001039571", "gene_names_uniprotkb": "HIBADH", "gene_names_refseq": "HIBADH", "protein_names_uniprotkb": "3-hydroxyisobutyrate dehydrogenase, mitochondrial; 1.1.1.31; HIBADH", "protein_names_refseq": "3-hydroxyisobutyrate dehydrogenase, mitochondrial precursor; 3-hydroxyisobutyrate dehydrogenase, mitochondrial", "tax_id": 9913, "disease": "", "pathway": " (bta:512002); (R-BTA-70895)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "26133183", "class_list": "", "function": "The g.-165 T>C rather than methylation is associated with semen motility in Chinese Holstein bulls by regulating the transcriptional activity of the HIBADH gene. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.1.1.31", "go_molecular_function": "GO:0051287 NAD binding;GO:0008442 3-hydroxyisobutyrate dehydrogenase activity;GO:0050661 NADP binding", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0006574 L-valine catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q2HJD7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q29RM1-1", "uniprot_id": "TPC_BOVIN", "mass": 35112.0, "length": 318, "protein_name": "Mitochondrial thiamine pyrophosphate carrier", "gene_name": "SLC25A19", "organism": "Bovine", "refseq_name": "mitochondrial thiamine pyrophosphate carrier", "refseq_ac": "NP_001039352", "gene_names_uniprotkb": "SLC25A19; DNC", "gene_names_refseq": "SLC25A19", "protein_names_uniprotkb": "Mitochondrial thiamine pyrophosphate carrier; Solute carrier family 25 member 19", "protein_names_refseq": "mitochondrial deoxynucleotide carrier; mitochondrial thiamine pyrophosphate carrier; mitochondrial uncoupling protein 1", "tax_id": 9913, "disease": "", "pathway": " (bta:504418); (R-BTA-196819)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Mitochondrial transporter mediating uptake of thiamine diphosphate into mitochondria. It is not clear if the antiporter activity is affected by the membrane potential or by the proton electrochemical gradient., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0015297 antiporter activity;GO:0090422 thiamine pyrophosphate transmembrane transporter activity;GO:0015234 thiamine transmembrane transporter activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane;GO:0031966 mitochondrial membrane;GO:0016020 membrane", "go_biological_process": "GO:0009229 thiamine diphosphate biosynthetic process;GO:0030974 thiamine pyrophosphate transmembrane transport;GO:0042723 thiamine-containing compound metabolic process;GO:0055085 transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q29RM1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q17QU6-1", "uniprot_id": "UIF_BOVIN", "mass": 35976.0, "length": 318, "protein_name": "UAP56-interacting factor", "gene_name": "FYTTD1", "organism": "Bovine", "refseq_name": "UAP56-interacting factor", "refseq_ac": "NP_001001137", "gene_names_uniprotkb": "FYTTD1; UIF", "gene_names_refseq": "FYTTD1", "protein_names_uniprotkb": "UAP56-interacting factor; Forty-two-three domain-containing protein 1; Protein 40-2-3", "protein_names_refseq": "40-2-3 protein; UAP56-interacting factor; forty-two-three domain-containing protein 1; protein 40-2-3", "tax_id": 9913, "disease": "", "pathway": " (bta:407149); (R-BTA-159236)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Required for mRNA export from the nucleus to the cytoplasm. Acts as an adapter that uses the DDX39B/UAP56-NFX1 pathway to ensure efficient mRNA export and delivering to the nuclear pore. Associates with spliced and unspliced mRNAs simultaneously with ALYREF/THOC4 (By similarity)., [UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "Q95M42", "ec_number_list": "", "go_molecular_function": "GO:0003729 mRNA binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0016607 nuclear speck", "go_biological_process": "GO:0006406 mRNA export from nucleus", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q17QU6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q17QE2-1", "uniprot_id": "LMCD1_BOVIN", "mass": 40723.0, "length": 363, "protein_name": "LIM and cysteine-rich domains protein 1", "gene_name": "LMCD1", "organism": "Bovine", "refseq_name": "LIM and cysteine-rich domains protein 1", "refseq_ac": "NP_001069690", "gene_names_uniprotkb": "LMCD1", "gene_names_refseq": "LMCD1", "protein_names_uniprotkb": "LIM and cysteine-rich domains protein 1", "protein_names_refseq": "LIM and cysteine-rich domains protein 1", "tax_id": 9913, "disease": "", "pathway": " (bta:540474); (R-BTA-5683826)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Transcriptional cofactor that restricts GATA6 function by inhibiting DNA-binding, resulting in repression of GATA6 transcriptional activation of downstream target genes. Represses GATA6-mediated trans activation of lung- and cardiac tissue-specific promoters. Inhibits DNA-binding by GATA4 and GATA1 to the cTNC promoter. Plays a critical role in the development of cardiac hypertrophy via activation of calcineurin/nuclear factor of activated T-cells signaling pathway (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0003714 transcription corepressor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0010611 regulation of cardiac muscle hypertrophy;GO:0070886 positive regulation of calcineurin-NFAT signaling cascade", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q17QE2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q29RR0-1", "uniprot_id": "RAB26_BOVIN", "mass": 27802.0, "length": 256, "protein_name": "Ras-related protein Rab-26", "gene_name": "RAB26", "organism": "Bovine", "refseq_name": "ras-related protein Rab-26", "refseq_ac": "NP_001039674", "gene_names_uniprotkb": "RAB26", "gene_names_refseq": "RAB26", "protein_names_uniprotkb": "Ras-related protein Rab-26; 3.6.5.2", "protein_names_refseq": "ras-related protein Rab-26", "tax_id": 9913, "disease": "", "pathway": " (bta:515675)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion (By similarity). RAB26 mediates transport of ADRA2A and ADRA2B from the Golgi to the cell membrane. Plays a role in the maturation of zymogenic granules and in pepsinogen secretion in the stomach (By similarity). Plays a role in the secretion of amylase from acinar granules in the parotid gland (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.6.5.2;3.6.5.5;3.6.5.-;3.6.5.3;2.7.11.1;3.6.1.5;3.6.1.15;3.6.5.4", "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0046872 metal ion binding;GO:0019002 GMP binding;GO:0003925 G protein activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005886 plasma membrane;GO:0030667 secretory granule membrane;GO:0030672 synaptic vesicle membrane;GO:0005802 trans-Golgi network", "go_biological_process": "GO:0045055 regulated exocytosis;GO:0016192 vesicle-mediated transport;GO:0043001 Golgi to plasma membrane protein transport;GO:0017157 regulation of exocytosis;GO:0035272 exocrine system development", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q29RR0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2HJH0-1", "uniprot_id": "LSM5_BOVIN", "mass": 9937.0, "length": 91, "protein_name": "U6 snRNA-associated Sm-like protein LSm5", "gene_name": "LSM5", "organism": "Bovine", "refseq_name": "U6 snRNA-associated Sm-like protein LSm5", "refseq_ac": "NP_001040018", "gene_names_uniprotkb": "LSM5", "gene_names_refseq": "LSM5", "protein_names_uniprotkb": "U6 snRNA-associated Sm-like protein LSm5", "protein_names_refseq": "LSM5 homolog, U6 small nuclear RNA associated; U6 snRNA-associated Sm-like protein 5; U6 snRNA-associated Sm-like protein LSm5", "tax_id": 9913, "disease": "", "pathway": " (bta:615136); (R-BTA-430039); (R-BTA-72163)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA., [UniProtKB, UniProtKB]; Plays a role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding;GO:0046982 protein heterodimerization activity", "go_cellular_component": "GO:0005634 nucleus;GO:0120115 Lsm2-8 complex;GO:0046540 U4/U6 x U5 tri-snRNP complex;GO:0005688 U6 snRNP;GO:1990726 Lsm1-7-Pat1 complex", "go_biological_process": "GO:0000398 mRNA splicing, via spliceosome", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2HJH0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q148H7-1", "uniprot_id": "K2C79_BOVIN", "mass": 57721.0, "length": 535, "protein_name": "Keratin, type II cytoskeletal 79", "gene_name": "KRT79", "organism": "Bovine", "refseq_name": "keratin, type II cytoskeletal 79", "refseq_ac": "NP_001068816", "gene_names_uniprotkb": "KRT79", "gene_names_refseq": "KRT79", "protein_names_uniprotkb": "Keratin, type II cytoskeletal 79; CK-79; Cytokeratin-79; K79; Keratin-79; Type-II keratin Kb38", "protein_names_refseq": "CK-79; K79; cytokeratin-79; keratin, type II cytoskeletal 79; type-II keratin Kb38", "tax_id": 9913, "disease": "", "pathway": " (bta:508202); (R-BTA-6805567); (R-BTA-6809371)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "41018975", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0019899 enzyme binding;GO:0030280 structural constituent of skin epidermis", "go_cellular_component": "GO:0045095 keratin filament", "go_biological_process": "GO:0031424 keratinization;GO:0045109 intermediate filament organization", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q148H7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q1JP63-1", "uniprot_id": "SVOP_BOVIN", "mass": 60748.0, "length": 548, "protein_name": "Synaptic vesicle 2-related protein", "gene_name": "SVOP", "organism": "Bovine", "refseq_name": "synaptic vesicle 2-related protein", "refseq_ac": "NP_001068909", "gene_names_uniprotkb": "SVOP", "gene_names_refseq": "SVOP", "protein_names_uniprotkb": "Synaptic vesicle 2-related protein; SV2-related protein", "protein_names_refseq": "SV2 related protein homolog; synaptic vesicle 2-related protein", "tax_id": 9913, "disease": "", "pathway": " (bta:510256)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "16305752;9801366", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q17QM3", "ec_number_list": "", "go_molecular_function": "GO:0022857 transmembrane transporter activity", "go_cellular_component": "GO:0030672 synaptic vesicle membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q1JP63-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KIA9-1", "uniprot_id": "ENOF1_BOVIN", "mass": 49621.0, "length": 443, "protein_name": "Mitochondrial enolase superfamily member 1", "gene_name": "ENOSF1", "organism": "Bovine", "refseq_name": "mitochondrial enolase superfamily member 1", "refseq_ac": "NP_001040015", "gene_names_uniprotkb": "ENOSF1", "gene_names_refseq": "ENOSF1", "protein_names_uniprotkb": "Mitochondrial enolase superfamily member 1; 4.2.1.68; L-fuconate dehydratase", "protein_names_refseq": "L-fuconate dehydratase; mitochondrial enolase superfamily member 1; rTS beta protein", "tax_id": 9913, "disease": "", "pathway": " (bta:615106)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Plays a role in the catabolism of L-fucose, a sugar that is part of the carbohydrates that are attached to cellular glycoproteins. Catalyzes the dehydration of L-fuconate to 2-keto-3-deoxy-L-fuconate by the abstraction of the 2-proton to generate an enediolate intermediate that is stabilized by the magnesium ion. May down-regulate thymidylate synthase activity, possibly already at the RNA level, by promoting the degradation of TYMS mRNA via an antisense RNA-based mechanism., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "4.2.1.68", "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0016836 hydro-lyase activity;GO:0016853 isomerase activity;GO:0050023 L-fuconate dehydratase activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0016052 carbohydrate catabolic process;GO:0009063 amino acid catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2KIA9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q29RK0-1", "uniprot_id": "ZN574_BOVIN", "mass": 99010.0, "length": 896, "protein_name": "Zinc finger protein 574", "gene_name": "ZNF574", "organism": "Bovine", "refseq_name": "zinc finger protein 574", "refseq_ac": "NP_001070007", "gene_names_uniprotkb": "ZNF574", "gene_names_refseq": "ZNF574", "protein_names_uniprotkb": "Zinc finger protein 574", "protein_names_refseq": "zinc finger protein 574", "tax_id": 9913, "disease": "", "pathway": " (bta:767618)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Part of a ribosome quality control that mediates surveillance of ribosome assembly and promotes degradation of ribosomes with assembly defects., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000976 transcription cis-regulatory region binding;GO:0043023 ribosomal large subunit binding;GO:0003677 DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0032502 developmental process;GO:1990116 ribosome-associated ubiquitin-dependent protein catabolic process;GO:0042256 cytosolic ribosome assembly;GO:0090069 regulation of ribosome biogenesis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q29RK0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q17QK6-1", "uniprot_id": "FBX2_BOVIN", "mass": 33601.0, "length": 297, "protein_name": "F-box only protein 2", "gene_name": "FBXO2", "organism": "Bovine", "refseq_name": "F-box only protein 2", "refseq_ac": "NP_001069037", "gene_names_uniprotkb": "FBXO2", "gene_names_refseq": "FBXO2", "protein_names_uniprotkb": "F-box only protein 2", "protein_names_refseq": "F-box only protein 2", "tax_id": 9913, "disease": "", "pathway": " (bta:512589); (R-BTA-8951664); (R-BTA-983168)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Involved in the endoplasmic reticulum-associated degradation pathway (ERAD) for misfolded lumenal proteins by recognizing and binding sugar chains on unfolded glycoproteins that are retrotranslocated into the cytosol and promoting their ubiquitination and subsequent degradation. Prevents formation of cytosolic aggregates of unfolded glycoproteins that have been retrotranslocated into the cytosol. Able to recognize and bind denatured glycoproteins, preferentially those of the high-mannose type (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0030246 carbohydrate binding;GO:0031249 denatured protein binding;GO:0001540 amyloid-beta binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0019005 SCF ubiquitin ligase complex;GO:0098978 glutamatergic synapse;GO:0043197 dendritic spine", "go_biological_process": "GO:0016567 protein ubiquitination;GO:0036503 ERAD pathway;GO:0006516 glycoprotein catabolic process;GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process;GO:0099576 regulation of protein catabolic process at postsynapse, modulating synaptic transmission", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q17QK6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q17QN2-1", "uniprot_id": "TOE1_BOVIN", "mass": 58546.0, "length": 524, "protein_name": "Target of EGR1 protein 1", "gene_name": "TOE1", "organism": "Bovine", "refseq_name": "target of EGR1 protein 1", "refseq_ac": "NP_001069062", "gene_names_uniprotkb": "TOE1", "gene_names_refseq": "TOE1", "protein_names_uniprotkb": "Target of EGR1 protein 1", "protein_names_refseq": "target of EGR1 protein 1; target of EGR1, member 1 (nuclear)", "tax_id": 9913, "disease": "", "pathway": " (bta:513052)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Inhibits cell growth rate and cell cycle. Induces CDKN1A expression as well as TGF-beta expression. Mediates the inhibitory growth effect of EGR1. Involved in the maturation of snRNAs and snRNA 3'-tail processing., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0017069 snRNA binding;GO:0000175 3'-5'-RNA exonuclease activity;GO:0004535 poly(A)-specific ribonuclease activity;GO:0003676 nucleic acid binding", "go_cellular_component": "GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0016607 nuclear speck;GO:0015030 Cajal body", "go_biological_process": "GO:0034472 snRNA 3'-end processing;GO:0016070 RNA metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q17QN2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KJC8-1", "uniprot_id": "FKBP9_BOVIN", "mass": 63535.0, "length": 574, "protein_name": "Peptidyl-prolyl cis-trans isomerase FKBP9", "gene_name": "FKBP9", "organism": "Bovine", "refseq_name": "peptidyl-prolyl cis-trans isomerase FKBP9 precursor", "refseq_ac": "NP_001039837", "gene_names_uniprotkb": "FKBP9", "gene_names_refseq": "FKBP-9; FKBP9", "protein_names_uniprotkb": "Peptidyl-prolyl cis-trans isomerase FKBP9; 5.2.1.8; FK506-binding protein 9; FKBP-9; PPIase FKBP9; Rotamase", "protein_names_refseq": "FK506 binding protein 9, 63 kDa; FK506-binding protein 9; PPIase FKBP9; peptidyl-prolyl cis-trans isomerase FKBP9 precursor; peptidyl-prolyl cis-trans isomerase FKBP9; rotamase", "tax_id": 9913, "disease": "", "pathway": " (bta:534182)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "PPIases accelerate the folding of proteins during protein synthesis., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 4, "predicted_n_glycosites": 4, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "5.2.1.8", "go_molecular_function": "GO:0005509 calcium ion binding;GO:0003755 peptidyl-prolyl cis-trans isomerase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum", "go_biological_process": "GO:0006457 protein folding", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2KJC8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q0VD53-1", "uniprot_id": "VP26A_BOVIN", "mass": 38156.0, "length": 327, "protein_name": "Vacuolar protein sorting-associated protein 26A", "gene_name": "VPS26A", "organism": "Bovine", "refseq_name": "vacuolar protein sorting-associated protein 26A", "refseq_ac": "NP_001068923", "gene_names_uniprotkb": "VPS26A", "gene_names_refseq": "VPS26A", "protein_names_uniprotkb": "Vacuolar protein sorting-associated protein 26A; Vesicle protein sorting 26A", "protein_names_refseq": "vacuolar protein sorting 26 A; vacuolar protein sorting 26 homolog A; vacuolar protein sorting-associated protein 26A; vesicle protein sorting 26A", "tax_id": 9913, "disease": "", "pathway": " (bta:510574); (R-BTA-3238698)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "Acts as a component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. The recruitment of the CSC to the endosomal membrane involves RAB7A and SNX3. The SNX-BAR retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN) and is involved in endosome-to-plasma membrane transport for cargo protein recycling. The SNX3-retromer mediates the retrograde endosome-to-TGN transport of WLS distinct from the SNX-BAR retromer pathway. The SNX27-retromer is believed to be involved in endosome-to-plasma membrane trafficking and recycling of a broad spectrum of cargo proteins. The CSC complex seems to act as recruitment hub for other proteins, such as the WASH complex and TBC1D5. Required for retrograde transport of lysosomal enzyme receptor IGF2R. Required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Required for the endosomal localization of WASHC2 (indicative for the WASH complex). Required for the endosomal localization of TBC1D5. Mediates retromer cargo recognition of SORL1 and is involved in trafficking of SORL1 implicated in sorting and processing of APP. Involved in retromer-independent lysosomal sorting of F2R. Involved in recycling of ADRB2. Acts redundantly with VSP26B in SNX-27 mediated endocytic recycling of SLC2A1/GLUT1. Enhances the affinity of SNX27 for PDZ-binding motifs in cargo proteins (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A5D9A4", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0030906 retromer, cargo-selective complex;GO:0005768 endosome;GO:0005769 early endosome;GO:0005829 cytosol;GO:0010008 endosome membrane", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0042147 retrograde transport, endosome to Golgi;GO:0032456 endocytic recycling", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q0VD53-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q17QT2-1", "uniprot_id": "MTUS1_BOVIN", "mass": 53476.0, "length": 467, "protein_name": "Microtubule-associated tumor suppressor 1 homolog", "gene_name": "MTUS1", "organism": "Bovine", "refseq_name": "microtubule-associated tumor suppressor 1 homolog isoform 2", "refseq_ac": "NP_001069160", "gene_names_uniprotkb": "MTUS1", "gene_names_refseq": "MTUS1", "protein_names_uniprotkb": "Microtubule-associated tumor suppressor 1 homolog; Mitochondrial tumor suppressor 1 homolog", "protein_names_refseq": "microtubule associated tumor suppressor 1; microtubule-associated tumor suppressor 1 homolog isoform 2; microtubule-associated tumor suppressor 1 homolog; mitochondrial tumor suppressor 1 homolog", "tax_id": 9913, "disease": "", "pathway": " (bta:515016)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Cooperates with AGTR2 to inhibit ERK2 activation and cell proliferation. May be required for AGTR2 cell surface expression. Together with PTPN6, induces UBE2V2 expression upon angiotensin-II stimulation (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 8, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008017 microtubule binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005739 mitochondrion;GO:0005794 Golgi apparatus;GO:0005886 plasma membrane;GO:0005730 nucleolus", "go_biological_process": "GO:0010758 regulation of macrophage chemotaxis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q17QT2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q1LZ83-1", "uniprot_id": "LACB2_BOVIN", "mass": 32683.0, "length": 288, "protein_name": "Endoribonuclease LACTB2", "gene_name": "LACTB2", "organism": "Bovine", "refseq_name": "endoribonuclease LACTB2", "refseq_ac": "NP_001069513", "gene_names_uniprotkb": "LACTB2", "gene_names_refseq": "LACTB2", "protein_names_uniprotkb": "Endoribonuclease LACTB2; 3.1.27.-; Beta-lactamase-like protein 2", "protein_names_refseq": "beta-lactamase-like protein 2; endoribonuclease LACTB2", "tax_id": 9913, "disease": "", "pathway": " (bta:535021)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Endoribonuclease; cleaves preferentially 3' to purine-pyrimidine dinucleotide motifs in single-stranded RNA. The cleavage product contains a free 3' -OH group. Has no activity with double-stranded RNA or DNA. Required for normal mitochondrial function and cell viability., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0016787 hydrolase activity;GO:0003727 single-stranded RNA binding;GO:0004521 RNA endonuclease activity", "go_cellular_component": "GO:0005759 mitochondrial matrix;GO:0005654 nucleoplasm;GO:0005794 Golgi apparatus;GO:0005829 cytosol", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q1LZ83-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q1JQB2-1", "uniprot_id": "BUB3_BOVIN", "mass": 36955.0, "length": 326, "protein_name": "Mitotic checkpoint protein BUB3", "gene_name": "BUB3", "organism": "Bovine", "refseq_name": "mitotic checkpoint protein BUB3", "refseq_ac": "NP_001069645", "gene_names_uniprotkb": "BUB3", "gene_names_refseq": "BUB3", "protein_names_uniprotkb": "Mitotic checkpoint protein BUB3", "protein_names_refseq": "BUB3 budding uninhibited by benzimidazoles 3 homolog; mitotic checkpoint protein BUB3", "tax_id": 9913, "disease": "", "pathway": " (bta:539594); (R-BTA-141430); (R-BTA-141444); (R-BTA-174184); (R-BTA-176409); (R-BTA-179409); (R-BTA-2467813); (R-BTA-2500257); (R-BTA-5663220); (R-BTA-9648025)", "pathway_count": 10, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "Has a dual function in spindle-assembly checkpoint signaling and in promoting the establishment of correct kinetochore-microtubule (K-MT) attachments. Promotes the formation of stable end-on bipolar attachments. Necessary for kinetochore localization of BUB1. Regulates chromosome segregation during oocyte meiosis. The BUB1/BUB3 complex plays a role in the inhibition of anaphase-promoting complex or cyclosome (APC/C) when spindle-assembly checkpoint is activated and inhibits the ubiquitin ligase activity of APC/C by phosphorylating its activator CDC20. This complex can also phosphorylate MAD1L1 (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A5D9G0", "ec_number_list": "", "go_molecular_function": "GO:0043130 ubiquitin binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0000776 kinetochore;GO:0033597 mitotic checkpoint complex;GO:1990298 bub1-bub3 complex;GO:0005634 nucleus", "go_biological_process": "GO:0007059 chromosome segregation;GO:0051301 cell division;GO:0007094 mitotic spindle assembly checkpoint signaling;GO:0051321 meiotic cell cycle;GO:0051983 regulation of chromosome segregation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q1JQB2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KJ37-1", "uniprot_id": "ERD22_BOVIN", "mass": 24454.0, "length": 212, "protein_name": "ER lumen protein-retaining receptor 2", "gene_name": "KDELR2", "organism": "Bovine", "refseq_name": "ER lumen protein-retaining receptor 2", "refseq_ac": "NP_001073247", "gene_names_uniprotkb": "KDELR2", "gene_names_refseq": "KDELR2", "protein_names_uniprotkb": "ER lumen protein-retaining receptor 2; KDEL endoplasmic reticulum protein retention receptor 2; KDEL receptor 2", "protein_names_refseq": "ER lumen protein-retaining receptor 2; KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2; KDEL receptor 2", "tax_id": 9913, "disease": "", "pathway": " (bta:531676); (R-BTA-6807878); (R-BTA-6811434)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Membrane receptor that binds the K-D-E-L sequence motif in the C-terminal part of endoplasmic reticulum resident proteins and maintains their localization in that compartment by participating to their vesicle-mediated recycling back from the Golgi (By similarity). Binding is pH dependent, and is optimal at pH 5-5.4 (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005046 KDEL sequence binding;GO:0046923 ER retention sequence binding", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005783 endoplasmic reticulum;GO:0016020 membrane;GO:0005789 endoplasmic reticulum membrane;GO:0005801 cis-Golgi network", "go_biological_process": "GO:0015031 protein transport;GO:0006890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum;GO:0006621 protein retention in ER lumen;GO:0035437 maintenance of protein localization in endoplasmic reticulum", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2KJ37-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KIN5-1", "uniprot_id": "HEM3_BOVIN", "mass": 39515.0, "length": 361, "protein_name": "Porphobilinogen deaminase", "gene_name": "HMBS", "organism": "Bovine", "refseq_name": "porphobilinogen deaminase", "refseq_ac": "NP_001039672", "gene_names_uniprotkb": "HMBS", "gene_names_refseq": "HMBS", "protein_names_uniprotkb": "Porphobilinogen deaminase; 2.5.1.61; HMBS; Hydroxymethylbilane synthase", "protein_names_refseq": "porphobilinogen deaminase", "tax_id": 9913, "disease": "", "pathway": " (bta:515614); (R-BTA-189451)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "As part of the heme biosynthetic pathway, catalyzes the sequential polymerization of four molecules of porphobilinogen to form hydroxymethylbilane, also known as preuroporphyrinogen. Catalysis begins with the assembly of the dipyrromethane cofactor by the apoenzyme from two molecules of porphobilinogen or from preuroporphyrinogen. The covalently linked cofactor acts as a primer, around which the tetrapyrrole product is assembled. In the last step of catalysis, the product, preuroporphyrinogen, is released, leaving the cofactor bound to the holodeaminase intact., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.5.1.61", "go_molecular_function": "GO:0004418 hydroxymethylbilane synthase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0006783 heme biosynthetic process;GO:0006782 protoporphyrinogen IX biosynthetic process;GO:0006784 heme A biosynthetic process;GO:0006785 heme B biosynthetic process;GO:0006779 porphyrin-containing compound biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2KIN5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2HJ57-1", "uniprot_id": "COTL1_BOVIN", "mass": 16010.0, "length": 142, "protein_name": "Coactosin-like protein", "gene_name": "COTL1", "organism": "Bovine", "refseq_name": "coactosin-like protein", "refseq_ac": "NP_001040058", "gene_names_uniprotkb": "COTL1", "gene_names_refseq": "COTL1", "protein_names_uniprotkb": "Coactosin-like protein", "protein_names_refseq": "coactosin-like 1; coactosin-like protein", "tax_id": 9913, "disease": "", "pathway": " (bta:617165); (R-BTA-6798695)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Binds to F-actin in a calcium-independent manner. Has no direct effect on actin depolymerization. Acts as a chaperone for ALOX5 (5LO), influencing both its stability and activity in leukotrienes synthesis (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0051015 actin filament binding;GO:0003779 actin binding;GO:0019899 enzyme binding", "go_cellular_component": "GO:0005634 nucleus;GO:0030864 cortical actin cytoskeleton;GO:0030427 site of polarized growth;GO:0005856 cytoskeleton;GO:0005829 cytosol", "go_biological_process": "GO:0030833 regulation of actin filament polymerization;GO:0050832 defense response to fungus", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2HJ57-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q29RL2-1", "uniprot_id": "CHRD1_BOVIN", "mass": 37427.0, "length": 332, "protein_name": "Cysteine and histidine-rich domain-containing protein 1", "gene_name": "CHORDC1", "organism": "Bovine", "refseq_name": "cysteine and histidine-rich domain-containing protein 1", "refseq_ac": "NP_001039377", "gene_names_uniprotkb": "CHORDC1", "gene_names_refseq": "CHORDC1; CHP-1", "protein_names_uniprotkb": "Cysteine and histidine-rich domain-containing protein 1; CHORD domain-containing protein 1; CHP-1; Protein morgana", "protein_names_refseq": "CHORD domain-containing protein 1; cysteine and histidine-rich domain (CHORD) containing 1; cysteine and histidine-rich domain-containing protein 1; protein morgana", "tax_id": 9913, "disease": "", "pathway": " (bta:505144)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Regulates centrosome duplication, probably by inhibiting the kinase activity of ROCK2. Proposed to act as co-chaperone for HSP90. May play a role in the regulation of NOD1 via a HSP90 chaperone complex. In vitro, has intrinsic chaperone activity. This function may be achieved by inhibiting association of ROCK2 with NPM1. Plays a role in ensuring the localization of the tyrosine kinase receptor EGFR to the plasma membrane, and thus ensures the subsequent regulation of EGFR activity and EGF-induced actin cytoskeleton remodeling. Involved in stress response. Prevents tumorigenesis., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0008270 zinc ion binding;GO:0043531 ADP binding;GO:0051879 Hsp90 protein binding;GO:0046872 metal ion binding", "go_cellular_component": "", "go_biological_process": "GO:0010824 regulation of centrosome duplication;GO:1900034 regulation of cellular response to heat;GO:0006457 protein folding;GO:0051298 centrosome duplication", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q29RL2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2HJ88-1", "uniprot_id": "RTCA_BOVIN", "mass": 39252.0, "length": 366, "protein_name": "RNA 3'-terminal phosphate cyclase", "gene_name": "RTCA", "organism": "Bovine", "refseq_name": "RNA 3'-terminal phosphate cyclase", "refseq_ac": "NP_001039520", "gene_names_uniprotkb": "RTCA; RTCD1", "gene_names_refseq": "RTCA; RTCD1", "protein_names_uniprotkb": "RNA 3'-terminal phosphate cyclase; 6.5.1.4; RNA cyclase; RNA terminal phosphate cyclase domain-containing protein 1; RNA-3'-phosphate cyclase", "protein_names_refseq": "RNA 3'-terminal phosphate cyclase; RNA cyclase; RNA terminal phosphate cyclase domain 1; RNA terminal phosphate cyclase domain-containing protein 1; RNA-3'-phosphate cyclase", "tax_id": 9913, "disease": "", "pathway": " (bta:510469)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA (By similarity). The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product (By similarity). Likely functions in some aspects of cellular RNA processing (By similarity). Function plays an important role in regulating axon regeneration by inhibiting central nervous system (CNS) axon regeneration following optic nerve injury (By similarity)., [UniProtKB, UniProtKB, UniProtKB]; Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. Likely functions in some aspects of cellular RNA processing. Function plays an important role in regulating axon regeneration by inhibiting central nervous system (CNS) axon regeneration following optic nerve injury., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "6.5.1.4", "go_molecular_function": "GO:0005524 ATP binding;GO:0003963 RNA-3'-phosphate cyclase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm", "go_biological_process": "GO:0006396 RNA processing;GO:1905592 negative regulation of optical nerve axon regeneration", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2HJ88-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KIA1-1", "uniprot_id": "RCAN3_BOVIN", "mass": 27425.0, "length": 241, "protein_name": "Calcipressin-3", "gene_name": "RCAN3", "organism": "Bovine", "refseq_name": "calcipressin-3", "refseq_ac": "NP_001039410", "gene_names_uniprotkb": "RCAN3; DSCR1L2", "gene_names_refseq": "DSCR1L2; RCAN3", "protein_names_uniprotkb": "Calcipressin-3; Down syndrome candidate region 1-like protein 2; Regulator of calcineurin 3", "protein_names_refseq": "Down syndrome critical region gene 1-like 2; calcipressin-3; down syndrome candidate region 1-like protein 2; regulator of calcineurin 3", "tax_id": 9913, "disease": "", "pathway": " (bta:506601)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Could play a role during central nervous system development (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003676 nucleic acid binding;GO:0019902 phosphatase binding;GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity;GO:0031013 troponin I binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0019722 calcium-mediated signaling", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2KIA1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KHY2-1", "uniprot_id": "VAMP5_BOVIN", "mass": 12778.0, "length": 116, "protein_name": "Vesicle-associated membrane protein 5", "gene_name": "VAMP5", "organism": "Bovine", "refseq_name": "vesicle-associated membrane protein 5", "refseq_ac": "NP_001039941", "gene_names_uniprotkb": "VAMP5", "gene_names_refseq": "VAMP5", "protein_names_uniprotkb": "Vesicle-associated membrane protein 5; VAMP-5", "protein_names_refseq": "VAMP-5; vesicle-associated membrane protein 5 (myobrevin); vesicle-associated membrane protein 5", "tax_id": 9913, "disease": "", "pathway": " (bta:540406)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "May participate in trafficking events that are associated with myogenesis, such as myoblast fusion and/or GLUT4 trafficking., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0005886 plasma membrane;GO:0009986 cell surface;GO:0048471 perinuclear region of cytoplasm;GO:0014704 intercalated disc", "go_biological_process": "GO:0030154 cell differentiation;GO:0007517 muscle organ development;GO:0043001 Golgi to plasma membrane protein transport;GO:0016192 vesicle-mediated transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2KHY2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KJB1-1", "uniprot_id": "SEP10_BOVIN", "mass": 52809.0, "length": 453, "protein_name": "Septin-10", "gene_name": "SEPTIN10", "organism": "Bovine", "refseq_name": "septin-10", "refseq_ac": "NP_001039641", "gene_names_uniprotkb": "SEPTIN10; SEPT10", "gene_names_refseq": "SEPT10; SEPTIN10", "protein_names_uniprotkb": "Septin-10", "protein_names_refseq": "septin-10", "tax_id": 9913, "disease": "", "pathway": " (bta:514603)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential)., [UniProtKB]; Filament-forming cytoskeletal GTPase., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0060090 molecular adaptor activity;GO:0003924 GTPase activity;GO:0005525 GTP binding", "go_cellular_component": "GO:0005940 septin ring;GO:0031514 motile cilium;GO:0015630 microtubule cytoskeleton;GO:0031105 septin complex;GO:0032153 cell division site", "go_biological_process": "GO:0008104 intracellular protein localization;GO:0061640 cytoskeleton-dependent cytokinesis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2KJB1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KI92-1", "uniprot_id": "IMP2L_BOVIN", "mass": 19937.0, "length": 177, "protein_name": "Mitochondrial inner membrane protease subunit 2", "gene_name": "IMMP2L", "organism": "Bovine", "refseq_name": "mitochondrial inner membrane protease subunit 2 isoform X2", "refseq_ac": "XP_024846827", "gene_names_uniprotkb": "IMMP2L", "gene_names_refseq": "IMMP2L", "protein_names_uniprotkb": "Mitochondrial inner membrane protease subunit 2; 3.4.21.-; IMP2-like protein", "protein_names_refseq": "mitochondrial inner membrane protease subunit 2 isoform X2", "tax_id": 9913, "disease": "", "pathway": " (bta:101902373)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space. Known to process the nuclear encoded protein DIABLO., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004175 endopeptidase activity;GO:0004252 serine-type endopeptidase activity;GO:0009003 signal peptidase activity", "go_cellular_component": "GO:0042720 mitochondrial inner membrane peptidase complex", "go_biological_process": "GO:0006627 protein processing involved in protein targeting to mitochondrion;GO:0006465 signal peptide processing", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2KI92-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q24K16-1", "uniprot_id": "PTGR3_BOVIN", "mass": 40119.0, "length": 377, "protein_name": "Prostaglandin reductase-3", "gene_name": "PTGR3", "organism": "Bovine", "refseq_name": "prostaglandin reductase-3", "refseq_ac": "NP_001069432", "gene_names_uniprotkb": "PTGR3; ZADH2", "gene_names_refseq": "PTGR-3; PTGR3; ZADH2", "protein_names_uniprotkb": "Prostaglandin reductase-3; 1.3.1.48; 15-oxoprostaglandin 13-reductase; PTGR-3; Zinc-binding alcohol dehydrogenase domain-containing protein 2", "protein_names_refseq": "15-oxoprostaglandin 13-reductase; prostaglandin reductase-3; zinc binding alcohol dehydrogenase domain containing 2; zinc-binding alcohol dehydrogenase domain-containing protein 2", "tax_id": 9913, "disease": "", "pathway": " (bta:532505)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Functions as 15-oxo-prostaglandin 13-reductase and acts on 15-keto-PGE1, 15-keto-PGE2, 15-keto-PGE1-alpha and 15-keto-PGE2-alpha with highest efficiency towards 15-keto-PGE2-alpha. Overexpression represses transcriptional activity of PPARG and inhibits adipocyte differentiation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.3.1.74;1.3.1.48", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0047522 15-oxoprostaglandin 13-reductase [NAD(P)+] activity", "go_cellular_component": "GO:0005777 peroxisome", "go_biological_process": "GO:0006629 lipid metabolic process;GO:0045599 negative regulation of fat cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q24K16-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q0VCP2-1", "uniprot_id": "PX11A_BOVIN", "mass": 28297.0, "length": 247, "protein_name": "Peroxisomal membrane protein 11A", "gene_name": "PEX11A", "organism": "Bovine", "refseq_name": "peroxisomal membrane protein 11A", "refseq_ac": "NP_001069189", "gene_names_uniprotkb": "PEX11A", "gene_names_refseq": "PEX11A", "protein_names_uniprotkb": "Peroxisomal membrane protein 11A; Peroxin-11A; Peroxisomal biogenesis factor 11A", "protein_names_refseq": "peroxin-11A; peroxisomal biogenesis factor 11A; peroxisomal membrane protein 11A", "tax_id": 9913, "disease": "", "pathway": " (bta:515608)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "May be involved in peroxisomal proliferation and may regulate peroxisomes division. May mediate binding of coatomer proteins to the peroxisomal membrane. Promotes membrane protrusion and elongation on the peroxisomal surface., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005778 peroxisomal membrane", "go_biological_process": "GO:0016559 peroxisome fission", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q0VCP2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q17QA1-1", "uniprot_id": "CCL4_BOVIN", "mass": 10184.0, "length": 92, "protein_name": "C-C motif chemokine 4", "gene_name": "CCL4", "organism": "Bovine", "refseq_name": "C-C motif chemokine 4 precursor", "refseq_ac": "NP_001068615", "gene_names_uniprotkb": "CCL4; SCY4A", "gene_names_refseq": "CCL4", "protein_names_uniprotkb": "C-C motif chemokine 4; Small-inducible cytokine A4", "protein_names_refseq": "C-C motif chemokine 4 precursor; C-C motif chemokine 4; chemokine (C-C motif) ligand 4; putative MIP1-beta protein; small-inducible cytokine A4", "tax_id": 9913, "disease": "", "pathway": " (bta:414347); (R-BTA-380108); (R-BTA-418594)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Monokine with inflammatory and chemokinetic properties., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008009 chemokine activity;GO:0048020 CCR chemokine receptor binding", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0006954 inflammatory response;GO:0030335 positive regulation of cell migration;GO:0061844 antimicrobial humoral immune response mediated by antimicrobial peptide;GO:0070098 chemokine-mediated signaling pathway;GO:0048245 eosinophil chemotaxis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q17QA1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KHY9-1", "uniprot_id": "PTSS1_BOVIN", "mass": 55416.0, "length": 473, "protein_name": "Phosphatidylserine synthase 1", "gene_name": "PTDSS1", "organism": "Bovine", "refseq_name": "phosphatidylserine synthase 1", "refseq_ac": "NP_001039505", "gene_names_uniprotkb": "PTDSS1", "gene_names_refseq": "PSS-1; PTDSS1", "protein_names_uniprotkb": "Phosphatidylserine synthase 1; 2.7.8.29; PSS-1; PtdSer synthase 1; Serine-exchange enzyme I", "protein_names_refseq": "phosphatidylserine synthase 1; ptdSer synthase 1; serine-exchange enzyme I", "tax_id": 9913, "disease": "", "pathway": " (bta:509819); (R-BTA-1483101)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "19393038", "class_list": "", "function": "Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) is replaced by L-serine., [UniProtKB, UniProtKB]; Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) or phosphatidylcholine (PC) is replaced by L-serine (By similarity). Catalyzes mainly the conversion of phosphatidylcholine but also converts, in vitro and to a lesser extent, phosphatidylethanolamine (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "F1MKI4", "ec_number_list": "2.7.8.29", "go_molecular_function": "GO:0106258 L-serine-phosphatidylcholine phosphatidyltransferase activity;GO:0106245 L-serine-phosphatidylethanolamine phosphatidyltransferase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006659 phosphatidylserine biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q2KHY9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q17QA0-1", "uniprot_id": "GEMI7_BOVIN", "mass": 13851.0, "length": 125, "protein_name": "Gem-associated protein 7", "gene_name": "GEMIN7", "organism": "Bovine", "refseq_name": "gem-associated protein 7", "refseq_ac": "NP_001069957", "gene_names_uniprotkb": "GEMIN7", "gene_names_refseq": "GEMIN7", "protein_names_uniprotkb": "Gem-associated protein 7; Gemin-7", "protein_names_refseq": "gem-associated protein 7; gemin 7", "tax_id": 9913, "disease": "", "pathway": " (bta:618024); (R-BTA-191859)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "The SMN complex catalyzes the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome, and thereby plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP (Sm core). In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP. To assemble core snRNPs, the SMN complex accepts the trapped 5Sm proteins from CLNS1A forming an intermediate. Binding of snRNA inside 5Sm triggers eviction of the SMN complex, thereby allowing binding of SNRPD3 and SNRPB to complete assembly of the core snRNP (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding", "go_cellular_component": "GO:0005829 cytosol;GO:0032797 SMN complex;GO:0034719 SMN-Sm protein complex;GO:0097504 Gemini of Cajal bodies;GO:0120114 Sm-like protein family complex", "go_biological_process": "GO:0000387 spliceosomal snRNP assembly;GO:0006397 mRNA processing;GO:0008380 RNA splicing", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q17QA0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q0VD23-1", "uniprot_id": "RFOX3_BOVIN", "mass": 35468.0, "length": 328, "protein_name": "RNA binding protein fox-1 homolog 3", "gene_name": "RBFOX3", "organism": "Bovine", "refseq_name": "RNA binding protein fox-1 homolog 3", "refseq_ac": "NP_001069005", "gene_names_uniprotkb": "RBFOX3", "gene_names_refseq": "HRNBP3; RBFOX3", "protein_names_uniprotkb": "RNA binding protein fox-1 homolog 3; Fox-1 homolog C", "protein_names_refseq": "RNA binding protein fox-1 homolog 3; fox-1 homolog C; hexaribonucleotide binding protein 3", "tax_id": 9913, "disease": "", "pathway": " (bta:511773)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Pre-mRNA alternative splicing regulator. Regulates alternative splicing of RBFOX2 to enhance the production of mRNA species that are targeted for nonsense-mediated decay (NMD)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; RNA-binding protein that regulates alternative splicing events., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003729 mRNA binding;GO:0003723 RNA binding;GO:0003677 DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005654 nucleoplasm;GO:0043204 perikaryon", "go_biological_process": "GO:0006397 mRNA processing;GO:0007399 nervous system development;GO:0008380 RNA splicing;GO:0000381 regulation of alternative mRNA splicing, via spliceosome", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q0VD23-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2HJ33-1", "uniprot_id": "OLA1_BOVIN", "mass": 44744.0, "length": 396, "protein_name": "Obg-like ATPase 1", "gene_name": "OLA1", "organism": "Bovine", "refseq_name": "obg-like ATPase 1", "refseq_ac": "NP_001039510", "gene_names_uniprotkb": "OLA1", "gene_names_refseq": "OLA1", "protein_names_uniprotkb": "Obg-like ATPase 1", "protein_names_refseq": "obg-like ATPase 1", "tax_id": 9913, "disease": "", "pathway": " (bta:509966); (R-BTA-114608)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0005525 GTP binding;GO:0046872 metal ion binding;GO:0016887 ATP hydrolysis activity;GO:0043023 ribosomal large subunit binding", "go_cellular_component": "GO:0005730 nucleolus;GO:0005737 cytoplasm", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2HJ33-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2HJF5-1", "uniprot_id": "DPH6_BOVIN", "mass": 29860.0, "length": 267, "protein_name": "Diphthine--ammonia ligase", "gene_name": "DPH6", "organism": "Bovine", "refseq_name": "diphthine--ammonia ligase", "refseq_ac": "NP_001070484", "gene_names_uniprotkb": "DPH6; ATPBD4", "gene_names_refseq": "ATPBD4; DPH6", "protein_names_uniprotkb": "Diphthine--ammonia ligase; 6.3.1.14; ATP-binding domain-containing protein 4; Diphthamide synthase; Diphthamide synthetase; Protein DPH6 homolog", "protein_names_refseq": "ATP binding domain 4; ATP-binding domain-containing protein 4; diphthamide synthase; diphthamide synthetase; diphthine--ammonia ligase; protein DPH6 homolog", "tax_id": 9913, "disease": "", "pathway": " (bta:767944); (R-BTA-5358493)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Amidase that catalyzes the last step of diphthamide biosynthesis using ammonium and ATP., [UniProtKB, UniProtKB]; Amidase that catalyzes the last step of diphthamide biosynthesis using ammonium and ATP. Diphthamide biosynthesis consists in the conversion of an L-histidine residue in the translation elongation factor eEF-2 (EEF2) to diphthamide (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "6.3.1.14;3.6.5.-", "go_molecular_function": "GO:0017178 diphthine-ammonia ligase activity;GO:0005524 ATP binding", "go_cellular_component": "", "go_biological_process": "GO:0017183 protein histidyl modification to diphthamide", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2HJF5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q17QV3-1", "uniprot_id": "SUMO3_BOVIN", "mass": 11669.0, "length": 104, "protein_name": "Small ubiquitin-related modifier 3", "gene_name": "SUMO3", "organism": "Bovine", "refseq_name": "small ubiquitin-related modifier 3", "refseq_ac": "NP_001069917", "gene_names_uniprotkb": "SUMO3", "gene_names_refseq": "SUMO-3; SUMO3", "protein_names_uniprotkb": "Small ubiquitin-related modifier 3; SUMO-3", "protein_names_refseq": "SMT3 homolog 1; SMT3 suppressor of mif two 3 homolog 3; small ubiquitin-related modifier 3 precursor (SMT3 homolog 1); small ubiquitin-related modifier 3; ubiquitin-like protein SMT3A", "tax_id": 9913, "disease": "", "pathway": " (bta:617236); (R-BTA-3065679); (R-BTA-3108214); (R-BTA-3232118); (R-BTA-3899300); (R-BTA-4090294); (R-BTA-4551638); (R-BTA-4615885); (R-BTA-4755510); (R-BTA-5696395)", "pathway_count": 10, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Ubiquitin-like protein which can be covalently attached to target lysines either as a monomer or as a lysine-linked polymer. Does not seem to be involved in protein degradation and may function as an antagonist of ubiquitin in the degradation process. Plays a role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Covalent attachment to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by an E3 ligase such as PIAS1-4, RANBP2 or CBX4. Plays a role in the regulation of sumoylation status of SETX (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0044389 ubiquitin-like protein ligase binding;GO:0031386 protein tag activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0016605 PML body", "go_biological_process": "GO:0016925 protein sumoylation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q17QV3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2HJ84-1", "uniprot_id": "PKNX1_BOVIN", "mass": 47204.0, "length": 436, "protein_name": "Homeobox protein PKNOX1", "gene_name": "PKNOX1", "organism": "Bovine", "refseq_name": "homeobox protein PKNOX1", "refseq_ac": "NP_001039815", "gene_names_uniprotkb": "PKNOX1; PREP1", "gene_names_refseq": "PKNOX1", "protein_names_uniprotkb": "Homeobox protein PKNOX1; PBX/knotted homeobox 1", "protein_names_refseq": "PBX/Knox1-related homeodomain containing polypeptide; PBX/knotted homeobox 1; homeobox protein PKNOX1", "tax_id": 9913, "disease": "", "pathway": " (bta:533382)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Activates transcription in the presence of PBX1A and HOXA1., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003682 chromatin binding;GO:0003700 DNA-binding transcription factor activity;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003677 DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005667 transcription regulator complex", "go_biological_process": "GO:0001525 angiogenesis;GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0006355 regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2HJ84-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KHX9-1", "uniprot_id": "MED9_BOVIN", "mass": 16116.0, "length": 145, "protein_name": "Mediator of RNA polymerase II transcription subunit 9", "gene_name": "MED9", "organism": "Bovine", "refseq_name": "mediator of RNA polymerase II transcription subunit 9", "refseq_ac": "NP_001074385", "gene_names_uniprotkb": "MED9; MED25", "gene_names_refseq": "MED9", "protein_names_uniprotkb": "Mediator of RNA polymerase II transcription subunit 9; Mediator complex subunit 9", "protein_names_refseq": "mediator of RNA polymerase II transcription subunit 9", "tax_id": 9913, "disease": "", "pathway": " (bta:616966)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003712 transcription coregulator activity", "go_cellular_component": "GO:0016592 mediator complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2KHX9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q148G2-1", "uniprot_id": "G6PC3_BOVIN", "mass": 38742.0, "length": 346, "protein_name": "Glucose-6-phosphatase 3", "gene_name": "G6PC3", "organism": "Bovine", "refseq_name": "glucose-6-phosphatase 3", "refseq_ac": "NP_899208", "gene_names_uniprotkb": "G6PC3", "gene_names_refseq": "G6PC3", "protein_names_uniprotkb": "Glucose-6-phosphatase 3; 3.1.3.9; G-6-Pase 3; G6Pase 3", "protein_names_refseq": "G-6-Pase 3; G6Pase 3; glucose-6-phosphatase 3; glucose-6-phosphatase catalytic subunit-related", "tax_id": 9913, "disease": "", "pathway": " (bta:369023); (R-BTA-70263)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Hydrolyzes glucose-6-phosphate to glucose in the endoplasmic reticulum. May form with the glucose-6-phosphate transporter (SLC37A4/G6PT) a ubiquitously expressed complex responsible for glucose production through glycogenolysis and gluconeogenesis. Probably required for normal neutrophil function (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q7YSF2", "ec_number_list": "3.1.3.25;3.1.3.9;3.1.3.94", "go_molecular_function": "GO:0004346 glucose-6-phosphatase activity", "go_cellular_component": "GO:0016020 membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006094 gluconeogenesis;GO:0051156 glucose 6-phosphate metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q148G2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2NKR7-1", "uniprot_id": "F162A_BOVIN", "mass": 17737.0, "length": 156, "protein_name": "Protein FAM162A", "gene_name": "FAM162A", "organism": "Bovine", "refseq_name": "protein FAM162A", "refseq_ac": "NP_001040057", "gene_names_uniprotkb": "FAM162A; E2IG5", "gene_names_refseq": "FAM162A", "protein_names_uniprotkb": "Protein FAM162A; E2-induced gene 5 protein homolog", "protein_names_refseq": "E2-induced gene 5 protein homolog; growth and transformation-dependent protein; protein FAM162A", "tax_id": 9913, "disease": "", "pathway": " (bta:617104)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Proposed to be involved in regulation of apoptosis; the exact mechanism may differ between cell types/tissues. May be involved in hypoxia-induced cell death of transformed cells implicating cytochrome C release and caspase activation (such as CASP9) and inducing mitochondrial permeability transition. May be involved in hypoxia-induced cell death of neuronal cells probably by promoting release of AIFM1 from mitochondria to cytoplasm and its translocation to the nucleus; however, the involvement of caspases has been reported conflictingly., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005739 mitochondrion;GO:0031966 mitochondrial membrane;GO:0016020 membrane", "go_biological_process": "GO:0043065 positive regulation of apoptotic process;GO:0051402 neuron apoptotic process;GO:0071456 cellular response to hypoxia;GO:0090200 positive regulation of release of cytochrome c from mitochondria", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2NKR7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q1LZC5-1", "uniprot_id": "ANR54_BOVIN", "mass": 32466.0, "length": 299, "protein_name": "Ankyrin repeat domain-containing protein 54", "gene_name": "ANKRD54", "organism": "Bovine", "refseq_name": "ankyrin repeat domain-containing protein 54", "refseq_ac": "NP_001069605", "gene_names_uniprotkb": "ANKRD54", "gene_names_refseq": "ANKRD54", "protein_names_uniprotkb": "Ankyrin repeat domain-containing protein 54", "protein_names_refseq": "ankyrin repeat domain-containing protein 54", "tax_id": 9913, "disease": "", "pathway": " (bta:538961)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Plays an important role in regulating intracellular signaling events associated with erythroid terminal differentiation., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0044877 protein-containing complex binding;GO:0019887 protein kinase regulator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0030496 midbody", "go_biological_process": "GO:0045648 positive regulation of erythrocyte differentiation;GO:1902531 regulation of intracellular signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q1LZC5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q29RH4-1", "uniprot_id": "THOC3_BOVIN", "mass": 38873.0, "length": 351, "protein_name": "THO complex subunit 3", "gene_name": "THOC3", "organism": "Bovine", "refseq_name": "THO complex subunit 3", "refseq_ac": "NP_001039765", "gene_names_uniprotkb": "THOC3", "gene_names_refseq": "THOC3", "protein_names_uniprotkb": "THO complex subunit 3; Tho3", "protein_names_refseq": "THO complex 3; THO complex subunit 3; tho3", "tax_id": 9913, "disease": "", "pathway": " (bta:529231); (R-BTA-159236)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. Required for efficient export of polyadenylated RNA and spliced mRNA. The THOC1-THOC2-THOC3 core complex alone is sufficient to bind export factor NXF1-NXT1 and promote ATPase activity of DDX39B. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NXF1 pathway., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding", "go_cellular_component": "GO:0016607 nuclear speck;GO:0000445 THO complex part of transcription export complex;GO:0000781 chromosome, telomeric region", "go_biological_process": "GO:0006397 mRNA processing;GO:0006406 mRNA export from nucleus;GO:0008380 RNA splicing", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q29RH4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q1JPG0-1", "uniprot_id": "MIGA2_BOVIN", "mass": 65433.0, "length": 593, "protein_name": "Mitoguardin 2", "gene_name": "MIGA2", "organism": "Bovine", "refseq_name": "mitoguardin 2", "refseq_ac": "NP_001069521", "gene_names_uniprotkb": "MIGA2; FAM73B", "gene_names_refseq": "FAM73B; MIGA2", "protein_names_uniprotkb": "Mitoguardin 2; Protein FAM73B", "protein_names_refseq": "family with sequence similarity 73, member B; mitoguardin 2; protein FAM73B", "tax_id": 9913, "disease": "", "pathway": " (bta:535315); (R-BTA-1483166)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "Regulator of mitochondrial fusion: acts by forming homo- and heterodimers at the mitochondrial outer membrane and facilitating the formation of PLD6/MitoPLD dimers. May act by regulating phospholipid metabolism via PLD6/MitoPLD., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 8, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0042803 protein homodimerization activity;GO:0046982 protein heterodimerization activity", "go_cellular_component": "GO:0005741 mitochondrial outer membrane;GO:0005829 cytosol;GO:0005886 plasma membrane", "go_biological_process": "GO:0008053 mitochondrial fusion", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q1JPG0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q0VCR4-1", "uniprot_id": "PPR3C_BOVIN", "mass": 36317.0, "length": 318, "protein_name": "Protein phosphatase 1 regulatory subunit 3C", "gene_name": "PPP1R3C", "organism": "Bovine", "refseq_name": "protein phosphatase 1 regulatory subunit 3C", "refseq_ac": "NP_001069632", "gene_names_uniprotkb": "PPP1R3C; PPP1R5", "gene_names_refseq": "PPP1R3C", "protein_names_uniprotkb": "Protein phosphatase 1 regulatory subunit 3C; PP1 subunit R5; PTG; Protein phosphatase 1 regulatory subunit 5; Protein targeting to glycogen", "protein_names_refseq": "PP1 subunit R5; PTG; R5; protein phosphatase 1 regulatory subunit 3C; protein phosphatase 1 regulatory subunit 5; protein phosphatase 1, regulatory (inhibitor) subunit 3C; protein targeting to glycogen", "tax_id": 9913, "disease": "", "pathway": " (bta:539466); (R-BTA-3322077)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "Acts as a glycogen-targeting subunit for PP1 and regulates its activity. Activates glycogen synthase, reduces glycogen phosphorylase activity and limits glycogen breakdown., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A7E3S7", "ec_number_list": "", "go_molecular_function": "GO:0060090 molecular adaptor activity;GO:0008157 protein phosphatase 1 binding;GO:0019903 protein phosphatase binding;GO:2001069 glycogen binding", "go_cellular_component": "GO:0000164 protein phosphatase type 1 complex;GO:0005829 cytosol", "go_biological_process": "GO:0005977 glycogen metabolic process;GO:0005978 glycogen biosynthetic process;GO:0005979 regulation of glycogen biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q0VCR4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KI95-1", "uniprot_id": "FHL2_BOVIN", "mass": 32101.0, "length": 279, "protein_name": "Four and a half LIM domains protein 2", "gene_name": "FHL2", "organism": "Bovine", "refseq_name": "four and a half LIM domains protein 2", "refseq_ac": "NP_001039511", "gene_names_uniprotkb": "FHL2", "gene_names_refseq": "FHL2", "protein_names_uniprotkb": "Four and a half LIM domains protein 2; FHL-2", "protein_names_refseq": "FHL-2; four and a half LIM domains protein 2", "tax_id": 9913, "disease": "", "pathway": " (bta:510008)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "May function as a molecular transmitter linking various signaling pathways to transcriptional regulation. Negatively regulates the transcriptional repressor E4F1 and may function in cell growth. Inhibits the transcriptional activity of FOXO1 and its apoptotic function by enhancing the interaction of FOXO1 with SIRT1 and FOXO1 deacetylation. Negatively regulates the calcineurin/NFAT signaling pathway in cardiomyocytes (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0003714 transcription corepressor activity;GO:0008134 transcription factor binding", "go_cellular_component": "GO:0005634 nucleus;GO:0030018 Z disc", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0043066 negative regulation of apoptotic process;GO:0070885 negative regulation of calcineurin-NFAT signaling cascade", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2KI95-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q17QU7-1", "uniprot_id": "DHR13_BOVIN", "mass": 40861.0, "length": 377, "protein_name": "Dehydrogenase/reductase SDR family member 13", "gene_name": "DHRS13", "organism": "Bovine", "refseq_name": "dehydrogenase/reductase SDR family member 13 precursor", "refseq_ac": "NP_001069155", "gene_names_uniprotkb": "DHRS13; SDR7C5", "gene_names_refseq": "DHRS13", "protein_names_uniprotkb": "Dehydrogenase/reductase SDR family member 13; 1.1.-.-; Protein SDR7C5; Short chain dehydrogenase/reductase family 7C member 5", "protein_names_refseq": "dehydrogenase/reductase SDR family member 13 precursor; dehydrogenase/reductase SDR family member 13; short chain dehydrogenase/reductase family 7C member 5", "tax_id": 9913, "disease": "", "pathway": " (bta:514903)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Putative oxidoreductase., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0016491 oxidoreductase activity", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q17QU7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q29RQ9-1", "uniprot_id": "ORML1_BOVIN", "mass": 17361.0, "length": 153, "protein_name": "ORM1-like protein 1", "gene_name": "ORMDL1", "organism": "Bovine", "refseq_name": "ORM1-like protein 1", "refseq_ac": "NP_001070601", "gene_names_uniprotkb": "ORMDL1", "gene_names_refseq": "ORMDL1", "protein_names_uniprotkb": "ORM1-like protein 1", "protein_names_refseq": "ORM1-like 1; ORM1-like protein 1", "tax_id": 9913, "disease": "", "pathway": " (bta:768077); (R-BTA-1660661)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Plays an essential role in the homeostatic regulation of sphingolipid de novo biosynthesis by modulating the activity of the serine palmitoyltransferase (SPT) in response to ceramide levels (By similarity). When complexed to SPT, the binding of ceramides to its N-terminus stabilizes a conformation that block SPT substrate entry, hence preventing SPT catalytic activity. Through this mechanism, maintains ceramide levels at sufficient concentrations for the production of complex sphingolipids, but which prevents the accumulation of ceramides to levels that trigger apoptosis (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0017059 serine palmitoyltransferase complex;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:2000303 regulation of ceramide biosynthetic process;GO:0030148 sphingolipid biosynthetic process;GO:0006672 ceramide metabolic process;GO:0090156 intracellular sphingolipid homeostasis;GO:0006665 sphingolipid metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q29RQ9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q1JQD6-1", "uniprot_id": "TAF1B_BOVIN", "mass": 69126.0, "length": 590, "protein_name": "TATA box-binding protein-associated factor RNA polymerase I subunit B", "gene_name": "TAF1B", "organism": "Bovine", "refseq_name": "TATA box-binding protein-associated factor RNA polymerase I subunit B", "refseq_ac": "NP_001068971", "gene_names_uniprotkb": "TAF1B", "gene_names_refseq": "TAF1B; TAFI63", "protein_names_uniprotkb": "TATA box-binding protein-associated factor RNA polymerase I subunit B; RNA polymerase I-specific TBP-associated factor 63 kDa; TAFI63; TATA box-binding protein-associated factor 1B; TBP-associated factor 1B; Transcription initiation factor SL1/TIF-IB subunit B", "protein_names_refseq": "RNA polymerase I-specific TBP-associated factor 63 kDa; TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa; TATA box-binding protein-associated factor 1B; TATA box-binding protein-associated factor RNA polymerase I subunit B; TBP-associated factor 1B; transcription initiation factor SL1/TIF-IB subunit B", "tax_id": 9913, "disease": "", "pathway": " (bta:511236); (R-BTA-5250924); (R-BTA-73762); (R-BTA-73772); (R-BTA-73863)", "pathway_count": 5, "publication_count": 1, "publication_id_list": "19393038", "class_list": "", "function": "Component of RNA polymerase I core factor complex that acts as a GTF2B/TFIIB-like factor and plays a key role in multiple steps during transcription initiation such as pre-initiation complex (PIC) assembly and postpolymerase recruitment events in polymerase I (Pol I) transcription. Binds rDNA promoters and plays a role in Pol I recruitment as a component of the SL1/TIF-IB complex and, possibly, directly through its interaction with RRN3., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "E1BGL1", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0001164 RNA polymerase I core promoter sequence-specific DNA binding", "go_cellular_component": "GO:0005668 RNA polymerase transcription factor SL1 complex;GO:0070860 RNA polymerase I core factor complex", "go_biological_process": "GO:0042790 nucleolar large rRNA transcription by RNA polymerase I;GO:0001188 RNA polymerase I preinitiation complex assembly;GO:0006355 regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q1JQD6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KHZ4-1", "uniprot_id": "MIA40_BOVIN", "mass": 15173.0, "length": 137, "protein_name": "Mitochondrial intermembrane space import and assembly protein 40", "gene_name": "CHCHD4", "organism": "Bovine", "refseq_name": "mitochondrial intermembrane space import and assembly protein 40", "refseq_ac": "NP_001039624", "gene_names_uniprotkb": "CHCHD4; MIA40", "gene_names_refseq": "CHCHD4", "protein_names_uniprotkb": "Mitochondrial intermembrane space import and assembly protein 40; Coiled-coil-helix-coiled-coil-helix domain-containing protein 4", "protein_names_refseq": "coiled-coil-helix-coiled-coil-helix domain-containing protein 4; mitochondrial intermembrane space import and assembly protein 40", "tax_id": 9913, "disease": "", "pathway": " (bta:513889)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Central component of a redox-sensitive mitochondrial intermembrane space import machinery which is required for the biogenesis of respiratory chain complexes. Functions as a chaperone and catalyzes the formation of disulfide bonds in substrate proteins, such as COA7, COX17, COX19, MICU1 and TIMCC/FAM136A. Required for the import and folding of small cysteine-containing proteins (small Tim) in the mitochondrial intermembrane space (IMS). Required for the import of COA7 in the IMS. Precursor proteins to be imported into the IMS are translocated in their reduced form into the mitochondria. The oxidized form of CHCHD4/MIA40 forms a transient intermolecular disulfide bridge with the reduced precursor protein, resulting in oxidation of the precursor protein that now contains an intramolecular disulfide bond and is able to undergo folding in the IMS. Reduced CHCHD4/MIA40 is then reoxidized by GFER/ERV1 via a disulfide relay system. Mediates formation of disulfide bond in MICU1 in the IMS, promoting formation of the MICU1-MICU2 heterodimer that regulates mitochondrial calcium uptake., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0015035 protein-disulfide reductase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005758 mitochondrial intermembrane space", "go_biological_process": "GO:0045041 protein import into mitochondrial intermembrane space;GO:0033108 mitochondrial respiratory chain complex assembly;GO:0051604 protein maturation;GO:0160203 mitochondrial disulfide relay system", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2KHZ4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q148C8-1", "uniprot_id": "MIEN1_BOVIN", "mass": 12342.0, "length": 115, "protein_name": "Migration and invasion enhancer 1", "gene_name": "MIEN1", "organism": "Bovine", "refseq_name": "migration and invasion enhancer 1", "refseq_ac": "NP_001068689", "gene_names_uniprotkb": "MIEN1; RDX12", "gene_names_refseq": "C17orf37; C19H17orf37; MIEN1", "protein_names_uniprotkb": "Migration and invasion enhancer 1", "protein_names_refseq": "migration and invasion enhancer 1; protein C17orf37 homolog", "tax_id": 9913, "disease": "", "pathway": " (bta:505710)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Increases cell migration by inducing filopodia formation at the leading edge of migrating cells. Plays a role in regulation of apoptosis, possibly through control of CASP3. May be involved in a redox-related process (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005829 cytosol;GO:0009898 cytoplasmic side of plasma membrane", "go_biological_process": "GO:0030335 positive regulation of cell migration;GO:0043066 negative regulation of apoptotic process;GO:0006915 apoptotic process;GO:0051491 positive regulation of filopodium assembly", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q148C8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q148F1-1", "uniprot_id": "COF2_BOVIN", "mass": 18737.0, "length": 166, "protein_name": "Cofilin-2", "gene_name": "CFL2", "organism": "Bovine", "refseq_name": "cofilin-2", "refseq_ac": "NP_001069622", "gene_names_uniprotkb": "CFL2", "gene_names_refseq": "CFL2", "protein_names_uniprotkb": "Cofilin-2; Cofilin, muscle isoform", "protein_names_refseq": "cofilin 2 (muscle); cofilin-2", "tax_id": 9913, "disease": "", "pathway": " (bta:539332)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner. It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0051015 actin filament binding;GO:0003779 actin binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0015629 actin cytoskeleton;GO:0016363 nuclear matrix;GO:0030018 Z disc", "go_biological_process": "GO:0051014 actin filament severing;GO:0007519 skeletal muscle tissue development;GO:0030042 actin filament depolymerization;GO:0030043 actin filament fragmentation;GO:0030836 positive regulation of actin filament depolymerization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q148F1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KIV9-1", "uniprot_id": "C1QB_BOVIN", "mass": 26399.0, "length": 247, "protein_name": "Complement C1q subcomponent subunit B", "gene_name": "C1QB", "organism": "Bovine", "refseq_name": "complement C1q subcomponent subunit B precursor", "refseq_ac": "NP_001040064", "gene_names_uniprotkb": "C1QB", "gene_names_refseq": "ADIA; C1QB", "protein_names_uniprotkb": "Complement C1q subcomponent subunit B", "protein_names_refseq": "adiponectin A; complement C1q subcomponent subunit B precursor; complement C1q subcomponent subunit B; complement component 1, q subcomponent, B chain", "tax_id": 9913, "disease": "", "pathway": " (bta:617435); (R-BTA-173623); (R-BTA-977606)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "6286235", "class_list": "", "function": "Core component of the complement C1 complex, a multiprotein complex that initiates the classical pathway of the complement system, a cascade of proteins that leads to phagocytosis and breakdown of pathogens and signaling that strengthens the adaptive immune system. The classical complement pathway is initiated by the C1Q subcomplex of the C1 complex, which specifically binds IgG or IgM immunoglobulins complexed with antigens, forming antigen-antibody complexes on the surface of pathogens: C1QA, together with C1QB and C1QC, specifically recognizes and binds the Fc regions of IgG or IgM via its C1q domain. Immunoglobulin-binding activates the proenzyme C1R, which cleaves C1S, initiating the proteolytic cascade of the complement system. The C1Q subcomplex is activated by a hexamer of IgG complexed with antigens, while it is activated by a pentameric IgM. The C1Q subcomplex also recognizes and binds phosphatidylserine exposed on the surface of cells undergoing programmed cell death, possibly promoting activation of the complement system., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0042802 identical protein binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0098888 extrinsic component of presynaptic membrane;GO:0098890 extrinsic component of postsynaptic membrane;GO:0005576 extracellular region;GO:0009986 cell surface", "go_biological_process": "GO:0045087 innate immune response;GO:0098883 synapse pruning;GO:0006958 complement activation, classical pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q2KIV9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q1RMR4-1", "uniprot_id": "RAB15_BOVIN", "mass": 24425.0, "length": 212, "protein_name": "Ras-related protein Rab-15", "gene_name": "RAB15", "organism": "Bovine", "refseq_name": "ras-related protein Rab-15", "refseq_ac": "NP_001040003", "gene_names_uniprotkb": "RAB15", "gene_names_refseq": "RAB15", "protein_names_uniprotkb": "Ras-related protein Rab-15; 3.6.5.2", "protein_names_refseq": "RAB15, member RAS onocogene family; ras-related protein Rab-15", "tax_id": 9913, "disease": "", "pathway": " (bta:614507); (R-BTA-8873719)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB15 may act in concert with RAB3A in regulating aspects of synaptic vesicle membrane flow within the nerve terminal., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.6.5.2;3.6.5.5;3.6.5.-;3.6.5.3;2.7.11.1;3.6.1.5;3.6.1.15;3.6.5.4;2.5.1.60", "go_molecular_function": "GO:0005525 GTP binding;GO:0046872 metal ion binding;GO:0003925 G protein activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0010008 endosome membrane;GO:0005929 cilium;GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "GO:0015031 protein transport;GO:0006887 exocytosis;GO:0032482 Rab protein signal transduction;GO:1903307 positive regulation of regulated secretory pathway;GO:0006898 receptor-mediated endocytosis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q1RMR4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q1JQA3-1", "uniprot_id": "AP3S2_BOVIN", "mass": 22035.0, "length": 193, "protein_name": "AP-3 complex subunit sigma-2", "gene_name": "AP3S2", "organism": "Bovine", "refseq_name": "AP-3 complex subunit sigma-2", "refseq_ac": "NP_001068844", "gene_names_uniprotkb": "AP3S2", "gene_names_refseq": "AP3S2", "protein_names_uniprotkb": "AP-3 complex subunit sigma-2; AP-3 complex subunit sigma-3B; Adaptor-related protein complex 3 subunit sigma-2; Sigma-3B-adaptin; Sigma-adaptin 3b; Sigma3B-adaptin", "protein_names_refseq": "AP-3 complex sigma-3B subunit; AP-3 complex subunit sigma-2; AP-3 complex subunit sigma-3B; adapter-related protein complex 3 sigma-2 subunit; adapter-related protein complex 3 subunit sigma-2; adaptor related protein complex 3 sigma 2 subunit; sigma-3B-adaptin; sigma-adaptin 3b; sigma3B-adaptin", "tax_id": 9913, "disease": "", "pathway": " (bta:508867)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0030659 cytoplasmic vesicle membrane;GO:0030123 AP-3 adaptor complex;GO:1904115 axon cytoplasm", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0016192 vesicle-mediated transport;GO:0008089 anterograde axonal transport;GO:0048490 anterograde synaptic vesicle transport;GO:0006896 Golgi to vacuole transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q1JQA3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q17QJ0-1", "uniprot_id": "ASF1B_BOVIN", "mass": 22421.0, "length": 202, "protein_name": "Histone chaperone ASF1B", "gene_name": "ASF1B", "organism": "Bovine", "refseq_name": "histone chaperone ASF1B", "refseq_ac": "NP_001068921", "gene_names_uniprotkb": "ASF1B", "gene_names_refseq": "ASF1B", "protein_names_uniprotkb": "Histone chaperone ASF1B; Anti-silencing function protein 1 homolog B", "protein_names_refseq": "ASF1 anti-silencing function 1 homolog B; anti-silencing function protein 1 homolog B; histone chaperone ASF1B", "tax_id": 9913, "disease": "", "pathway": " (bta:510538)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. Cooperates with chromatin assembly factor 1 (CAF-1) to promote replication-dependent chromatin assembly. Also involved in the nuclear import of the histone H3-H4 dimer together with importin-4 (IPO4): specifically recognizes and binds newly synthesized histones with the monomethylation of H3 'Lys-9' (H3K9me1) and diacetylation at 'Lys-5' and 'Lys-12' of H4 (H4K5ac and H4K12ac) marks in the cytosol. Does not participate in replication-independent nucleosome deposition which is mediated by ASF1A and HIRA. Required for gonad development., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0042393 histone binding;GO:0140713 histone chaperone activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0000785 chromatin;GO:0032991 protein-containing complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006334 nucleosome assembly;GO:0006335 DNA replication-dependent chromatin assembly;GO:0006325 chromatin organization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q17QJ0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q1JQ91-1", "uniprot_id": "RPB4_BOVIN", "mass": 16327.0, "length": 142, "protein_name": "DNA-directed RNA polymerase II subunit RPB4", "gene_name": "POLR2D", "organism": "Bovine", "refseq_name": "DNA-directed RNA polymerase II subunit RPB4", "refseq_ac": "NP_001069926", "gene_names_uniprotkb": "POLR2D", "gene_names_refseq": "POLR2D", "protein_names_uniprotkb": "DNA-directed RNA polymerase II subunit RPB4; DNA-directed RNA polymerase II subunit D; RNA polymerase II subunit B4", "protein_names_refseq": "DNA-directed RNA polymerase II subunit D; DNA-directed RNA polymerase II subunit RPB4; RNA polymerase II polypeptide D; RNA polymerase II subunit B4; polymerase (RNA) II (DNA directed) polypeptide D", "tax_id": 9913, "disease": "", "pathway": " (bta:617422); (R-BTA-112382); (R-BTA-113418); (R-BTA-5578749); (R-BTA-674695); (R-BTA-6781823); (R-BTA-6782135); (R-BTA-6782210); (R-BTA-6796648); (R-BTA-6803529); (R-BTA-6807505); (R-BTA-72086); (R-BTA-72163); (R-BTA-72165); (R-BTA-72203); (R-BTA-73776); (R-BTA-73779); (R-BTA-75953); (R-BTA-75955); (R-BTA-76042); (R-BTA-77075); (R-BTA-9018519); (R-BTA-9770562)", "pathway_count": 23, "publication_count": 3, "publication_id_list": "16769904;26789250;28892040", "class_list": "", "function": "Core component of RNA polymerase II (Pol II), a DNA-dependent RNA polymerase which synthesizes mRNA precursors and many functional non-coding RNAs using the four ribonucleoside triphosphates as substrates. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. POLR2D/RPB4 is part of a subcomplex with POLR2G/RPB7 that binds to a pocket formed by POLR2A/RPB1, POLR2B/RPB2 and POLR2F/RPABC2 at the base of the clamp element. The POLR2D/RPB4-POLR2G/RPB7 subcomplex seems to lock the clamp via POLR2G/RPB7 in the closed conformation thus preventing double-stranded DNA to enter the active site cleft. The POLR2D/RPB4-POLR2G/RPB7 subcomplex binds single-stranded DNA and RNA., [UniProtKB, PubMed, PubMed, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0000166 nucleotide binding;GO:0031369 translation initiation factor binding", "go_cellular_component": "GO:0005665 RNA polymerase II, core complex;GO:0005634 nucleus;GO:0000428 DNA-directed RNA polymerase complex;GO:0016607 nuclear speck", "go_biological_process": "GO:0006367 transcription initiation at RNA polymerase II promoter;GO:0006352 DNA-templated transcription initiation;GO:0006368 transcription elongation by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q1JQ91-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KHV2-1", "uniprot_id": "PACC1_BOVIN", "mass": 40135.0, "length": 350, "protein_name": "Proton-activated chloride channel", "gene_name": "PACC1", "organism": "Bovine", "refseq_name": "proton-activated chloride channel", "refseq_ac": "NP_001040045", "gene_names_uniprotkb": "PACC1; TMEM206", "gene_names_refseq": "C16H1orf75; C1orf75; PACC1; PAC; TMEM206", "protein_names_uniprotkb": "Proton-activated chloride channel; PAC; Transmembrane protein 206", "protein_names_refseq": "proton-activated chloride channel; transmembrane protein 206", "tax_id": 9913, "disease": "", "pathway": " (bta:616392)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Chloride channel gated by pH that facilitates the entry of chloride ions into cells upon exposure to extracellular acidic pH. Involved in acidosis-induced cell death by mediating chloride influx and subsequent cell swelling., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 1, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 1, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 1, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "5.6.1.6;1.8.-.-;1.8.5.1", "go_molecular_function": "GO:0061797 pH-gated chloride channel activity;GO:0005254 chloride channel activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0034707 chloride channel complex", "go_biological_process": "GO:0006821 chloride transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q2KHV2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q17QM4-1", "uniprot_id": "EPT1_BOVIN", "mass": 45214.0, "length": 397, "protein_name": "Ethanolaminephosphotransferase 1", "gene_name": "SELENOI", "organism": "Bovine", "refseq_name": "ethanolaminephosphotransferase 1", "refseq_ac": "NP_001068725", "gene_names_uniprotkb": "SELENOI", "gene_names_refseq": "EPT1; SELENOI; SELI; hEPT1", "protein_names_uniprotkb": "Ethanolaminephosphotransferase 1; 2.7.8.1; SelI; Selenoprotein I", "protein_names_refseq": "ethanolaminephosphotransferase 1 (CDP-ethanolamine-specific); ethanolaminephosphotransferase 1", "tax_id": 9913, "disease": "", "pathway": " (bta:506381); (R-BTA-1483213)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Ethanolaminephosphotransferase that catalyzes the transfer of phosphoethanolamine (PE) from CDP-ethanolamine to lipid acceptors, the final step in the synthesis of PE via the 'Kennedy' pathway. PE is the second most abundant phospholipid of membranes in mammals and is involved in various membrane-related cellular processes. The enzyme is critical for the synthesis of several PE species and also catalyzes the synthesis of plasmanyl-PE, a lipid required for proper myelination and neurodevelopment, from 1-alkyl-2-acylglycerol., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; The multi-pass transmembrane protein encoded by this gene belongs to the CDP-alcohol phosphatidyltransferase class-I family. It catalyzes the transfer of phosphoethanolamine from CDP-ethanolamine to diacylglycerol to produce phosphatidylethanolamine, which is involved in the formation and maintenance of vesicular membranes, regulation of lipid metabolism, and protein folding. This protein is a selenoprotein, containing the rare selenocysteine (Sec) amino acid at its active site. Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. A pseudogene of this locus has been identified on chromosome 7. [provided by RefSeq, Sep 2017]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.8.2;2.7.8.1;2.7.8.22", "go_molecular_function": "GO:0046872 metal ion binding;GO:0004307 ethanolaminephosphotransferase activity", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0008611 ether lipid biosynthetic process;GO:0042552 myelination;GO:0006646 phosphatidylethanolamine biosynthetic process;GO:0008654 phospholipid biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q17QM4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KHU4-1", "uniprot_id": "CLPP_BOVIN", "mass": 29704.0, "length": 272, "protein_name": "ATP-dependent Clp protease proteolytic subunit, mitochondrial", "gene_name": "CLPP", "organism": "Bovine", "refseq_name": "ATP-dependent Clp protease proteolytic subunit, mitochondrial", "refseq_ac": "NP_001039879", "gene_names_uniprotkb": "CLPP", "gene_names_refseq": "CLPP", "protein_names_uniprotkb": "ATP-dependent Clp protease proteolytic subunit, mitochondrial; 3.4.21.92; Endopeptidase Clp", "protein_names_refseq": "ATP-dependent Clp protease proteolytic subunit, mitochondrial; ClpP caseinolytic peptidase, ATP-dependent, proteolytic subunit homolog; caseinolytic peptidase, ATP-dependent, proteolytic subunit; endopeptidase Clp; putative ATP-dependent Clp protease proteolytic subunit, mitochondrial", "tax_id": 9913, "disease": "", "pathway": " (bta:535981); (R-BTA-9837999)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Protease component of the ClpXP complex that cleaves peptides and various proteins in an ATP-dependent process. Has low peptidase activity in the absence of CLPX. The ClpXP complex can degrade CSN1S1, CSN2 and CSN3, as well as synthetic peptides (in vitro) and may be responsible for a fairly general and central housekeeping function rather than for the degradation of specific substrates. Cleaves PINK1 in the mitochondrion., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.1.1.35;5.3.3.21;2.7.11.-;2.3.1.37;1.2.4.1;5.3.3.8;2.3.1.41;3.6.4.10;1.8.1.4;3.5.3.1;5.6.1.7;7.1.2.2;7.1.1.2;1.2.1.3;4.2.1.3;4.98.1.1;1.1.1.30;1.1.1.42;1.3.8.5;1.2.4.2;2.3.3.1;2.3.1.9;3.4.21.92;1.1.1.37;6.2.1.-;6.2.1.4", "go_molecular_function": "GO:0004252 serine-type endopeptidase activity;GO:0051117 ATPase binding;GO:0004176 ATP-dependent peptidase activity", "go_cellular_component": "GO:0005759 mitochondrial matrix;GO:0009368 endopeptidase Clp complex", "go_biological_process": "GO:0051603 proteolysis involved in protein catabolic process;GO:0033619 membrane protein proteolysis;GO:0006515 protein quality control for misfolded or incompletely synthesized proteins;GO:0006508 proteolysis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2KHU4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q28028-1", "uniprot_id": "IL15_BOVIN", "mass": 18555.0, "length": 162, "protein_name": "Interleukin-15", "gene_name": "IL15", "organism": "Bovine", "refseq_name": "interleukin-15 precursor", "refseq_ac": "NP_776515", "gene_names_uniprotkb": "IL15", "gene_names_refseq": "IL15", "protein_names_uniprotkb": "Interleukin-15; IL-15", "protein_names_refseq": "IL-15; interleukin-15 precursor", "tax_id": 9913, "disease": "", "pathway": " (bta:281248); (R-BTA-8983432)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "12429727;31358322;9282828", "class_list": "", "function": "Cytokine that plays a major role in the development of inflammatory and protective immune responses to microbial invaders and parasites by modulating immune cells of both the innate and adaptive immune systems. Stimulates the proliferation of natural killer cells, T-cells and B-cells and promotes the secretion of several cytokines. In monocytes, induces the production of IL8 and monocyte chemotactic protein 1/CCL2, two chemokines that attract neutrophils and monocytes respectively to sites of infection. Unlike most cytokines, which are secreted in soluble form, IL15 is expressed in association with its high affinity IL15RA on the surface of IL15-producing cells and delivers signals to target cells that express IL2RB and IL2RG receptor subunits. Binding to its receptor triggers the phosphorylation of JAK1 and JAK3 and the recruitment and subsequent phosphorylation of signal transducer and activator of transcription-3/STAT3 and STAT5 (By similarity). In mast cells, induces the rapid tyrosine phosphorylation of STAT6 and thereby controls mast cell survival and release of cytokines such as IL4 (By similarity)., [UniProtKB, UniProtKB, UniProtKB]; IL-15 inhibited adipogenic differentiation of bone marrow-derived mesenchymal stem cells via regulating the crosstalk between STAT5A and Akt signaling pathways., [RefSeq, PubMed]; Increased function and survival of IL-15-transduced dendritic cells are mediated by up-regulation of IL-15Ralpha and Bcl-2., [RefSeq, PubMed]", "predicted_glycosites": 4, "predicted_n_glycosites": 4, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005125 cytokine activity;GO:0005126 cytokine receptor binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005737 cytoplasm;GO:0016607 nuclear speck", "go_biological_process": "GO:0032740 positive regulation of interleukin-17 production;GO:0006955 immune response;GO:0001819 positive regulation of cytokine production;GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation;GO:0050766 positive regulation of phagocytosis", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q28028-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q1LZA3-1", "uniprot_id": "ASNS_BOVIN", "mass": 64220.0, "length": 561, "protein_name": "Asparagine synthetase [glutamine-hydrolyzing]", "gene_name": "ASNS", "organism": "Bovine", "refseq_name": "asparagine synthetase [glutamine-hydrolyzing]", "refseq_ac": "NP_001069121", "gene_names_uniprotkb": "ASNS", "gene_names_refseq": "ASNS", "protein_names_uniprotkb": "Asparagine synthetase [glutamine-hydrolyzing]; 6.3.5.4; Glutamine-dependent asparagine synthetase", "protein_names_refseq": "asparagine synthetase [glutamine-hydrolyzing]; glutamine-dependent asparagine synthetase", "tax_id": 9913, "disease": "", "pathway": " (bta:514209); (R-BTA-8963693)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "6.3.5.4", "go_molecular_function": "GO:0005524 ATP binding;GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0070981 L-asparagine biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q1LZA3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q17QZ4-1", "uniprot_id": "TFDP1_BOVIN", "mass": 44926.0, "length": 410, "protein_name": "Transcription factor Dp-1", "gene_name": "TFDP1", "organism": "Bovine", "refseq_name": "transcription factor Dp-1", "refseq_ac": "NP_001069497", "gene_names_uniprotkb": "TFDP1", "gene_names_refseq": "TFDP1", "protein_names_uniprotkb": "Transcription factor Dp-1", "protein_names_refseq": "transcription factor Dp-1", "tax_id": 9913, "disease": "", "pathway": " (bta:534579); (R-BTA-1538133); (R-BTA-2173796); (R-BTA-69231); (R-BTA-8953750)", "pathway_count": 5, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Can stimulate E2F-dependent transcription. Binds DNA cooperatively with E2F family members through the E2 recognition site, 5'-TTTC[CG]CGC-3', found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The E2F1:DP complex appears to mediate both cell proliferation and apoptosis. Blocks adipocyte differentiation by repressing CEBPA binding to its target gene promoters (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0019904 protein domain specific binding;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000987 cis-regulatory region sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005667 transcription regulator complex;GO:0090575 RNA polymerase II transcription regulator complex", "go_biological_process": "GO:0070345 negative regulation of fat cell proliferation;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0051726 regulation of cell cycle;GO:0000122 negative regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q17QZ4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q1JQA0-1", "uniprot_id": "PPT2_BOVIN", "mass": 34627.0, "length": 305, "protein_name": "Lysosomal thioesterase PPT2", "gene_name": "PPT2", "organism": "Bovine", "refseq_name": "lysosomal thioesterase PPT2 precursor", "refseq_ac": "NP_001030395", "gene_names_uniprotkb": "PPT2", "gene_names_refseq": "PPT2", "protein_names_uniprotkb": "Lysosomal thioesterase PPT2; 3.1.2.2; PPT-2", "protein_names_refseq": "PPT-2; lysosomal thioesterase PPT2 precursor; lysosomal thioesterase PPT2", "tax_id": 9913, "disease": "", "pathway": " (bta:516797); (R-BTA-75105)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "Catalyzes the cleavage of thioester bonds from S-palmitoyl-CoA or S-palmitoyl-N-acetylcysteamine (unbranched structures) but does not have activity against palmitoylcysteine or palmitoylated proteins, branched structures or bulky head groups. Conversely, hydrolyzes both long and short chain fatty acyl-CoA substrate., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q58CW8", "ec_number_list": "3.1.2.2;3.1.2.22;3.1.2.14;3.5.2.6;3.1.1.4;3.1.1.5;3.1.2.27;3.1.2.1;3.1.2.11;3.1.2.3;3.1.2.5;3.1.2.-;2.3.1.16;2.3.1.9", "go_molecular_function": "GO:0047617 fatty acyl-CoA hydrolase activity;GO:0016790 thiolester hydrolase activity;GO:0098599 palmitoyl hydrolase activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0005764 lysosome", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q1JQA0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q28050-1", "uniprot_id": "S10A7_BOVIN", "mass": 11544.0, "length": 101, "protein_name": "Protein S100-A7", "gene_name": "S100A7", "organism": "Bovine", "refseq_name": "protein S100-A7", "refseq_ac": "NP_777021", "gene_names_uniprotkb": "S100A7; CAAF2", "gene_names_refseq": "S100A7", "protein_names_uniprotkb": "Protein S100-A7; CAAF2; Calcium-binding protein in amniotic fluid 2; Dander minor allergen BDA11; Dermal allergen BDA11; S100 calcium-binding protein A7", "protein_names_refseq": "CAAF2; S100 calcium-binding protein A7 (psoriasin 1); calcium-binding protein in amniotic fluid 2; dander minor allergen BDA11; dermal allergen BDA11; protein S100-A7", "tax_id": 9913, "disease": "", "pathway": " (bta:282344); (R-BTA-6798695); (R-BTA-6799990)", "pathway_count": 3, "publication_count": 5, "publication_id_list": "20074874;29604144;29774569;7594639;8941350", "class_list": "", "function": "Psoriasin appears to be a part of the local host defence mechanisms in the udder and seems to be inducible by infection with E. coli., [RefSeq, PubMed]; Study of nonsynonymous DNA variation in the functional domain of the S100A7, -A8, -A9 genes in taurine cattle and yak, [RefSeq, PubMed]; The findings indicated that plasma concentrations of S100A7 and S100A8 did not change significantly during pregnancy in cows., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A5PJH5", "ec_number_list": "", "go_molecular_function": "GO:0046914 transition metal ion binding;GO:0048306 calcium-dependent protein binding;GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0005737 cytoplasm", "go_biological_process": "GO:0043542 endothelial cell migration", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q28050-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q0VCN1-1", "uniprot_id": "NMRL1_BOVIN", "mass": 33154.0, "length": 299, "protein_name": "NmrA-like family domain-containing protein 1", "gene_name": "NMRAL1", "organism": "Bovine", "refseq_name": "nmrA-like family domain-containing protein 1", "refseq_ac": "NP_001069500", "gene_names_uniprotkb": "NMRAL1", "gene_names_refseq": "NMRAL1", "protein_names_uniprotkb": "NmrA-like family domain-containing protein 1", "protein_names_refseq": "NmrA-like family domain containing 1; nmrA-like family domain-containing protein 1", "tax_id": 9913, "disease": "", "pathway": " (bta:534628); (R-BTA-70635)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Redox sensor protein. Undergoes restructuring and subcellular redistribution in response to changes in intracellular NADPH/NADP(+) levels. At low NADPH concentrations the protein is found mainly as a monomer, and binds argininosuccinate synthase (ASS1), the enzyme involved in nitric oxide synthesis. Association with ASS1 impairs its activity and reduces the production of nitric oxide, which subsequently prevents apoptosis. Under normal NADPH concentrations, the protein is found as a dimer and hides the binding site for ASS1. The homodimer binds one molecule of NADPH. Has higher affinity for NADPH than for NADP(+). Binding to NADPH is necessary to form a stable dimer (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q0VCN1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q0VCQ7-1", "uniprot_id": "ICE2_BOVIN", "mass": 109914.0, "length": 981, "protein_name": "Little elongation complex subunit 2", "gene_name": "ICE2", "organism": "Bovine", "refseq_name": "little elongation complex subunit 2", "refseq_ac": "NP_001069733", "gene_names_uniprotkb": "ICE2; NARG2", "gene_names_refseq": "ICE2; NARG2", "protein_names_uniprotkb": "Little elongation complex subunit 2; Interactor of little elongator complex ELL subunit 2; NMDA receptor-regulated protein 2", "protein_names_refseq": "NMDA receptor regulated 2; NMDA receptor-regulated protein 2; interactor of little elongator complex ELL subunit 2; little elongation complex subunit 2", "tax_id": 9913, "disease": "", "pathway": " (bta:541255)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0008023 transcription elongation factor complex;GO:0015030 Cajal body;GO:0000791 euchromatin;GO:0035363 histone locus body", "go_biological_process": "GO:0045945 positive regulation of transcription by RNA polymerase III;GO:0042795 snRNA transcription by RNA polymerase II;GO:0042796 snRNA transcription by RNA polymerase III", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q0VCQ7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q0VCR1-1", "uniprot_id": "RTF2_BOVIN", "mass": 33149.0, "length": 299, "protein_name": "Replication termination factor 2", "gene_name": "RTF2", "organism": "Bovine", "refseq_name": "replication termination factor 2", "refseq_ac": "NP_001069093", "gene_names_uniprotkb": "RTF2; RTFDC1", "gene_names_refseq": "C13H20orf43; RTF2; RTFDC1", "protein_names_uniprotkb": "Replication termination factor 2; RTF2; Replication termination factor 2 domain-containing protein 1", "protein_names_refseq": "UPF0549 protein C20orf43 homolog; protein RTF2 homolog; replication termination factor 2 domain containing 1; replication termination factor 2 domain-containing protein 1; replication termination factor 2", "tax_id": 9913, "disease": "", "pathway": " (bta:513536)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Replication termination factor which is a component of the elongating replisome. Required for ATR pathway signaling upon DNA damage and has a positive activity during DNA replication. Might function to facilitate fork pausing at replication fork barriers like the rDNA. May be globally required to stimulate ATR signaling after the fork stalls or encounters a lesion. Interacts with nascent DNA., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005657 replication fork", "go_biological_process": "GO:0097752 regulation of DNA stability;GO:0072711 cellular response to hydroxyurea", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q0VCR1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q0VCR2-1", "uniprot_id": "CXA5_BOVIN", "mass": 40403.0, "length": 359, "protein_name": "Gap junction alpha-5 protein", "gene_name": "GJA5", "organism": "Bovine", "refseq_name": "gap junction alpha-5 protein", "refseq_ac": "NP_001071490", "gene_names_uniprotkb": "GJA5", "gene_names_refseq": "CXNI; GJA5", "protein_names_uniprotkb": "Gap junction alpha-5 protein; Connexin-40; Cx40", "protein_names_refseq": "connexin I; connexin-40; cx40; gap junction alpha-5 protein; gap junction protein, alpha 5, 40kDa", "tax_id": 9913, "disease": "", "pathway": " (bta:539491)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0086076 gap junction channel activity involved in atrial cardiac muscle cell-AV node cell electrical coupling", "go_cellular_component": "GO:0005922 connexin complex", "go_biological_process": "GO:0007267 cell-cell signaling;GO:0007507 heart development;GO:0086044 atrial cardiac muscle cell to AV node cell communication by electrical coupling", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q0VCR2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q0VCS6-1", "uniprot_id": "CLC1A_BOVIN", "mass": 32094.0, "length": 278, "protein_name": "C-type lectin domain family 1 member A", "gene_name": "CLEC1A", "organism": "Bovine", "refseq_name": "C-type lectin domain family 1 member A", "refseq_ac": "NP_001069549", "gene_names_uniprotkb": "CLEC1A; CLEC1", "gene_names_refseq": "CLEC1A", "protein_names_uniprotkb": "C-type lectin domain family 1 member A; C-type lectin-like receptor 1; CLEC-1", "protein_names_refseq": "C-type lectin domain family 1 member A; C-type lectin-like receptor 1; CLEC-1", "tax_id": 9913, "disease": "", "pathway": " (bta:536944)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "22771795", "class_list": "", "function": "These results suggest that IRBIT may reduce the apparent affinity for Mg(2+)(i) in inhibition of NBCe1-B activity in mammalian cells., [RefSeq, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004888 transmembrane signaling receptor activity;GO:0030246 carbohydrate binding", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007165 signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q0VCS6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q0VCT1-1", "uniprot_id": "AF1Q_BOVIN", "mass": 10075.0, "length": 90, "protein_name": "Protein AF1q", "gene_name": "MLLT11", "organism": "Bovine", "refseq_name": "protein AF1q", "refseq_ac": "NP_001069637", "gene_names_uniprotkb": "MLLT11; AF1Q", "gene_names_refseq": "MLLT11", "protein_names_uniprotkb": "Protein AF1q", "protein_names_refseq": "myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); myeloid/lymphoid or mixed-lineage leukemia; protein AF1q; translocated to, 11", "tax_id": 9913, "disease": "", "pathway": " (bta:539519)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Cofactor for the transcription factor TCF7. Involved in regulation of lymphoid development by driving multipotent hematopoietic progenitor cells towards a T-cell fate., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005813 centrosome;GO:0005829 cytosol", "go_biological_process": "GO:0043065 positive regulation of apoptotic process;GO:0045893 positive regulation of DNA-templated transcription;GO:0097191 extrinsic apoptotic signaling pathway;GO:0090200 positive regulation of release of cytochrome c from mitochondria;GO:0097193 intrinsic apoptotic signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q0VCT1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q0VCT4-1", "uniprot_id": "CLTRN_BOVIN", "mass": 25288.0, "length": 222, "protein_name": "Collectrin", "gene_name": "CLTRN", "organism": "Bovine", "refseq_name": "collectrin precursor", "refseq_ac": "NP_001069071", "gene_names_uniprotkb": "CLTRN; TMEM27", "gene_names_refseq": "CLTRN; TMEM27", "protein_names_uniprotkb": "Collectrin; Transmembrane protein 27", "protein_names_refseq": "collectrin precursor; collectrin; transmembrane protein 27", "tax_id": 9913, "disease": "", "pathway": " (bta:513188)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Plays an important role in amino acid transport by acting as binding partner of amino acid transporters SLC6A18 and SLC6A19, regulating their trafficking on the cell surface and their activity (By similarity). May also play a role in trafficking of amino acid transporters SLC3A1 and SLC7A9 to the renal cortical cell membrane (By similarity). Regulator of SNARE complex function (By similarity). Stimulator of beta cell replication (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0051957 positive regulation of amino acid transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q0VCT4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q0VCU7-1", "uniprot_id": "SGCG_BOVIN", "mass": 32179.0, "length": 291, "protein_name": "Gamma-sarcoglycan", "gene_name": "SGCG", "organism": "Bovine", "refseq_name": "gamma-sarcoglycan", "refseq_ac": "NP_001068712", "gene_names_uniprotkb": "SGCG", "gene_names_refseq": "SGCG", "protein_names_uniprotkb": "Gamma-sarcoglycan; Gamma-SG", "protein_names_refseq": "gamma-SG; gamma-sarcoglycan; sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)", "tax_id": 9913, "disease": "", "pathway": " (bta:506155); (R-BTA-9913351)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005856 cytoskeleton;GO:0042383 sarcolemma;GO:0016012 sarcoglycan complex", "go_biological_process": "GO:0060047 heart contraction;GO:0048738 cardiac muscle tissue development", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q0VCU7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q0VCW1-1", "uniprot_id": "SPOP_BOVIN", "mass": 42132.0, "length": 374, "protein_name": "Speckle-type POZ protein", "gene_name": "SPOP", "organism": "Bovine", "refseq_name": "speckle-type POZ protein", "refseq_ac": "NP_001069404", "gene_names_uniprotkb": "SPOP", "gene_names_refseq": "SPOP", "protein_names_uniprotkb": "Speckle-type POZ protein", "protein_names_refseq": "speckle-type POZ protein", "tax_id": 9913, "disease": "", "pathway": " (bta:530618); (R-BTA-5632684); (R-BTA-9929491)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination of target proteins, leading most often to their proteasomal degradation. In complex with CUL3, involved in ubiquitination and proteasomal degradation of BRMS1, DAXX, PDX1/IPF1, GLI2 and GLI3. In complex with CUL3, involved in ubiquitination of MACROH2A1 and BMI1; this does not lead to their proteasomal degradation. Inhibits transcriptional activation of PDX1/IPF1 targets, such as insulin, by promoting PDX1/IPF1 degradation. The cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex containing homodimeric SPOP has higher ubiquitin ligase activity than the complex that contains the heterodimer formed by SPOP and SPOPL. Involved in the regulation of bromodomain and extra-terminal motif (BET) proteins BRD2, BRD3, BRD4 stability.Plays an essential role for proper translation, but not for their degradation, of critical DNA replication licensing factors CDT1 and CDC6, thereby participating in DNA synthesis and cell proliferation. Regulates interferon regulatory factor 1/IRF1 proteasomal turnover by targeting S/T-rich degrons in IRF1 (By similarity). Involved in ubiquitination of BRDT and promotes its degradation, thereby regulates histone removal in early condensing spermatids prior to histone-to-protamine exchange (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0042802 identical protein binding;GO:0031625 ubiquitin protein ligase binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0016607 nuclear speck;GO:0031463 Cul3-RING ubiquitin ligase complex", "go_biological_process": "GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0030162 regulation of proteolysis;GO:0000209 protein polyubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q0VCW1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q0VCW3-1", "uniprot_id": "BANP_BOVIN", "mass": 54820.0, "length": 503, "protein_name": "Protein BANP", "gene_name": "BANP", "organism": "Bovine", "refseq_name": "protein BANP", "refseq_ac": "NP_001069088", "gene_names_uniprotkb": "BANP", "gene_names_refseq": "BANP", "protein_names_uniprotkb": "Protein BANP", "protein_names_refseq": "protein BANP", "tax_id": 9913, "disease": "", "pathway": " (bta:513446)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Controls V(D)J recombination during T-cell development by repressing T-cell receptor (TCR) beta enhancer function. Binds to scaffold/matrix attachment region beta (S/MARbeta), an ATC-rich DNA sequence located upstream of the TCR beta enhancer. Represses cyclin D1 transcription by recruiting HDAC1 to its promoter, thereby diminishing H3K9ac, H3S10ph and H4K8ac levels. Promotes TP53 activation, which causes cell cycle arrest. Plays a role in the regulation of alternative splicing. Binds to CD44 pre-mRNA and negatively regulates the inclusion of CD44 proximal variable exons v2-v6 but has no effect on distal variable exons v7-v10., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0003723 RNA binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0016607 nuclear speck", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006325 chromatin organization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q0VCW3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q0VCW8-1", "uniprot_id": "PDCL3_BOVIN", "mass": 27479.0, "length": 240, "protein_name": "Phosducin-like protein 3", "gene_name": "PDCL3", "organism": "Bovine", "refseq_name": "phosducin-like protein 3", "refseq_ac": "NP_001069113", "gene_names_uniprotkb": "PDCL3", "gene_names_refseq": "PDCL3", "protein_names_uniprotkb": "Phosducin-like protein 3", "protein_names_refseq": "phosducin-like protein 3", "tax_id": 9913, "disease": "", "pathway": " (bta:514033)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Acts as a chaperone for the angiogenic VEGF receptor KDR/VEGFR2, increasing its abundance by inhibiting its ubiquitination and degradation (By similarity). Inhibits the folding activity of the chaperonin-containing T-complex (CCT) which leads to inhibition of cytoskeletal actin folding (By similarity). Acts as a chaperone during heat shock alongside HSP90 and HSP40/70 chaperone complexes (By similarity). Modulates the activation of caspases during apoptosis (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0043184 vascular endothelial growth factor receptor 2 binding;GO:0044183 protein folding chaperone", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005783 endoplasmic reticulum;GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "GO:0001525 angiogenesis;GO:0010628 positive regulation of gene expression;GO:0006915 apoptotic process;GO:0006457 protein folding", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q0VCW8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q0VCX5-1", "uniprot_id": "ERF1_BOVIN", "mass": 49031.0, "length": 437, "protein_name": "Eukaryotic peptide chain release factor subunit 1", "gene_name": "ETF1", "organism": "Bovine", "refseq_name": "eukaryotic peptide chain release factor subunit 1", "refseq_ac": "NP_001069722", "gene_names_uniprotkb": "ETF1", "gene_names_refseq": "ETF1; RRF1", "protein_names_uniprotkb": "Eukaryotic peptide chain release factor subunit 1; Eukaryotic release factor 1; eRF1", "protein_names_refseq": "eRF1; eukaryotic peptide chain release factor subunit 1; eukaryotic release factor 1", "tax_id": 9913, "disease": "", "pathway": " (bta:541077); (R-BTA-72764); (R-BTA-9629569); (R-BTA-975956); (R-BTA-975957)", "pathway_count": 5, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of the eRF1-eRF3-GTP ternary complex, a ternary complex that mediates translation termination in response to the termination codons. The eRF1-eRF3-GTP complex binds to a stop codon in the ribosomal A-site. ETF1/ERF1 is responsible for stop codon recognition and inducing hydrolysis of peptidyl-tRNA. Following GTP hydrolysis, eRF3 (GSPT1/ERF3A or GSPT2/ERF3B) dissociates, permitting ETF1/eRF1 to accommodate fully in the A-site, followed by hydrolysis of peptidyl-tRNA. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Required for SHFL-mediated translation termination which inhibits programmed ribosomal frameshifting (-1PRF) of mRNA from viruses and cellular genes., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004045 peptidyl-tRNA hydrolase activity;GO:1990825 sequence-specific mRNA binding;GO:0008079 translation termination factor activity;GO:0016149 translation release factor activity, codon specific", "go_cellular_component": "GO:0018444 translation release factor complex;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0022626 cytosolic ribosome", "go_biological_process": "GO:0006449 regulation of translational termination;GO:0002184 cytoplasmic translational termination;GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q0VCX5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q0VD05-1", "uniprot_id": "CCG3_BOVIN", "mass": 35500.0, "length": 315, "protein_name": "Voltage-dependent calcium channel gamma-3 subunit", "gene_name": "CACNG3", "organism": "Bovine", "refseq_name": "voltage-dependent calcium channel gamma-3 subunit", "refseq_ac": "NP_001071482", "gene_names_uniprotkb": "CACNG3", "gene_names_refseq": "CACNG3", "protein_names_uniprotkb": "Voltage-dependent calcium channel gamma-3 subunit; Neuronal voltage-gated calcium channel gamma-3 subunit; TARP gamma-3; Transmembrane AMPAR regulatory protein gamma-3", "protein_names_refseq": "TARP gamma-3; calcium channel, voltage-dependent, gamma subunit 3; neuronal voltage-gated calcium channel gamma-3 subunit; transmembrane AMPAR regulatory protein gamma-3; voltage-dependent calcium channel gamma-3 subunit", "tax_id": 9913, "disease": "", "pathway": " (bta:538496); (R-BTA-399719); (R-BTA-5682910)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005245 voltage-gated calcium channel activity;GO:0016247 channel regulator activity;GO:0005262 calcium channel activity", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0032281 AMPA glutamate receptor complex;GO:0036477 somatodendritic compartment;GO:0098839 postsynaptic density membrane;GO:0098685 Schaffer collateral - CA1 synapse", "go_biological_process": "GO:0006605 protein targeting;GO:0051968 positive regulation of synaptic transmission, glutamatergic;GO:0019226 transmission of nerve impulse;GO:0008104 intracellular protein localization;GO:2000311 regulation of AMPA receptor activity", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q0VD05-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q0VD15-1", "uniprot_id": "ORML3_BOVIN", "mass": 17495.0, "length": 153, "protein_name": "ORM1-like protein 3", "gene_name": "ORMDL3", "organism": "Bovine", "refseq_name": "ORM1-like protein 3", "refseq_ac": "NP_001069835", "gene_names_uniprotkb": "ORMDL3", "gene_names_refseq": "ORMDL3", "protein_names_uniprotkb": "ORM1-like protein 3", "protein_names_refseq": "ORM1-like 3; ORM1-like protein 3", "tax_id": 9913, "disease": "", "pathway": " (bta:615368); (R-BTA-1660661); (R-BTA-6798695)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Plays an essential role in the homeostatic regulation of sphingolipid de novo biosynthesis by modulating the activity of the serine palmitoyltransferase (SPT) in response to ceramide levels. When complexed to SPT, the binding of ceramides to its N-terminus stabilizes a conformation that block SPT substrate entry, hence preventing SPT catalytic activity. Through this mechanism, maintains ceramide levels at sufficient concentrations for the production of complex sphingolipids, but which prevents the accumulation of ceramides to levels that trigger apoptosis., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0017059 serine palmitoyltransferase complex;GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:2000303 regulation of ceramide biosynthetic process;GO:0030148 sphingolipid biosynthetic process;GO:0006672 ceramide metabolic process;GO:0090156 intracellular sphingolipid homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q0VD15-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q0VD24-1", "uniprot_id": "SETMR_BOVIN", "mass": 34254.0, "length": 306, "protein_name": "Histone-lysine N-methyltransferase SETMAR", "gene_name": "SETMAR", "organism": "Bovine", "refseq_name": "histone-lysine N-methyltransferase SETMAR", "refseq_ac": "NP_001068976", "gene_names_uniprotkb": "SETMAR", "gene_names_refseq": "SETMAR", "protein_names_uniprotkb": "Histone-lysine N-methyltransferase SETMAR; 2.1.1.357; SET domain and mariner transposase fusion protein homolog", "protein_names_refseq": "SET domain and mariner transposase fusion gene-containing protein homolog; SET domain and mariner transposase fusion protein homolog; histone-lysine N-methyltransferase SETMAR", "tax_id": 9913, "disease": "", "pathway": " (bta:511299)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Histone methyltransferase that methylates 'Lys-4' and 'Lys-36' of histone H3, 2 specific tags for epigenetic transcriptional activation. Specifically mediates dimethylation of H3 'Lys-36'., [UniProtKB, UniProtKB]; This gene encodes a histone-lysine N-methyltransferase that may be involved in the methylation of histone H3. In anthropoid primates this gene is a fusion gene of a SET histone-lysine N-methyltransferase and a mariner (MAR) family transposase. In all other species this gene contains only the SET domain. [provided by RefSeq, Feb 2013]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.1.1.357", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0003690 double-stranded DNA binding;GO:0042054 histone methyltransferase activity;GO:0042800 histone H3K4 methyltransferase activity;GO:0140954 histone H3K36 dimethyltransferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005694 chromosome", "go_biological_process": "GO:0032259 methylation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q0VD24-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q0VD27-1", "uniprot_id": "ENOPH_BOVIN", "mass": 28930.0, "length": 261, "protein_name": "Enolase-phosphatase E1", "gene_name": "ENOPH1", "organism": "Bovine", "refseq_name": "enolase-phosphatase E1", "refseq_ac": "NP_001069343", "gene_names_uniprotkb": "ENOPH1; MASA", "gene_names_refseq": "ENOPH1", "protein_names_uniprotkb": "Enolase-phosphatase E1; 2,3-diketo-5-methylthio-1-phosphopentane phosphatase; 3.1.3.77; MASA homolog", "protein_names_refseq": "2,3-diketo-5-methylthio-1-phosphopentane phosphatase; E-1 enzyme; MASA homolog; enolase-phosphatase E1", "tax_id": 9913, "disease": "", "pathway": " (bta:525563); (R-BTA-1237112)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene)., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.1.3.77", "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0043874 acireductone synthase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0019509 L-methionine salvage from methylthioadenosine", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q0VD27-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q0VFX9-1", "uniprot_id": "GGACT_BOVIN", "mass": 19052.0, "length": 168, "protein_name": "Gamma-glutamylaminecyclotransferase", "gene_name": "GGACT", "organism": "Bovine", "refseq_name": "gamma-glutamylaminecyclotransferase", "refseq_ac": "NP_001069039", "gene_names_uniprotkb": "GGACT; A2LD1", "gene_names_refseq": "A2LD1; GGACT", "protein_names_uniprotkb": "Gamma-glutamylaminecyclotransferase; 4.3.2.8; AIG2-like domain-containing protein 1; GGACT; Gamma-glutamylamine cyclotransferase", "protein_names_refseq": "AIG2-like domain 1; AIG2-like domain-containing protein 1; gamma-glutamylaminecyclotransferase", "tax_id": 9913, "disease": "", "pathway": " (bta:512596)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Contributes to degradation of proteins cross-linked by transglutaminases by degrading the cross-link between a lysine and a glutamic acid residue. Catalyzes the formation of 5-oxo-L-proline from L-gamma-glutamyl-L-epsilon-lysine. Inactive with L-gamma-glutamyl-alpha-amino acid substrates such as L-gamma-glutamyl-L-alpha-cysteine and L-gamma-glutamyl-L-alpha-alanine., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "4.3.2.8", "go_molecular_function": "GO:0061929 gamma-glutamylaminecyclotransferase activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0042219 modified amino acid catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q0VFX9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q0X0C4-1", "uniprot_id": "HEXI1_BOVIN", "mass": 36317.0, "length": 320, "protein_name": "Protein HEXIM1", "gene_name": "HEXIM1", "organism": "Bovine", "refseq_name": "protein HEXIM1", "refseq_ac": "NP_001069649", "gene_names_uniprotkb": "HEXIM1", "gene_names_refseq": "HEXIM1", "protein_names_uniprotkb": "Protein HEXIM1", "protein_names_refseq": "HMBA-inducible 1; hexamethylene bisacetamide inducible 1; protein HEXIM1", "tax_id": 9913, "disease": "", "pathway": " (bta:539696)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "23537346", "class_list": "", "function": "The authors demonstrate that bovine hexamethylene bisacetamide-induced protein 1 (BHEXIM1) inhibits the bovine immunodeficiency virus-mediated BIV LTR transcription. In vivo and in vitro assays show direct binding of BHEXIM1 to the bovine cyclin T1. Publication Status: Online-Only, [RefSeq, PubMed]; Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor. Core component of the 7SK RNP complex: in cooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation. May also regulate NF-kappa-B, ESR1, NR3C1 and CIITA-dependent transcriptional activity. Plays a role in the regulation of DNA virus-mediated innate immune response by assembling into the HDP-RNP complex, a complex that serves as a platform for IRF3 phosphorylation and subsequent innate immune response activation through the cGAS-STING pathway., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0042802 identical protein binding;GO:0097322 7SK snRNA binding;GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity;GO:0106140 P-TEFb complex binding;GO:0140416 transcription regulator inhibitor activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0120259 7SK snRNP", "go_biological_process": "GO:0032897 negative regulation of viral transcription;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0045087 innate immune response;GO:0002218 activation of innate immune response", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q0X0C4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q0X0E2-1", "uniprot_id": "HEXI2_BOVIN", "mass": 32804.0, "length": 287, "protein_name": "Protein HEXIM2", "gene_name": "HEXIM2", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "HEXIM2", "gene_names_refseq": "", "protein_names_uniprotkb": "Protein HEXIM2", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor. Core component of the 7SK RNP complex: in cooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 8, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0097322 7SK snRNA binding;GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005737 cytoplasm", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q0X0E2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q148C3-1", "uniprot_id": "LY6D_BOVIN", "mass": 13365.0, "length": 128, "protein_name": "Lymphocyte antigen 6D", "gene_name": "LY6D", "organism": "Bovine", "refseq_name": "lymphocyte antigen 6D precursor", "refseq_ac": "NP_001069985", "gene_names_uniprotkb": "LY6D", "gene_names_refseq": "LY6D", "protein_names_uniprotkb": "Lymphocyte antigen 6D; Ly-6D", "protein_names_refseq": "ly-6D; lymphocyte antigen 6 complex, locus D; lymphocyte antigen 6D precursor; lymphocyte antigen 6D", "tax_id": 9913, "disease": "", "pathway": " (bta:618714); (R-BTA-163125)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "May act as a specification marker at earliest stage specification of lymphocytes between B- and T-cell development. Marks the earliest stage of B-cell specification (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane;GO:0009986 cell surface;GO:0098552 side of membrane", "go_biological_process": "GO:0035634 response to stilbenoid;GO:0030098 lymphocyte differentiation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q148C3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q148C4-1", "uniprot_id": "PCP4_BOVIN", "mass": 6817.0, "length": 62, "protein_name": "Calmodulin regulator protein PCP4", "gene_name": "PCP4", "organism": "Bovine", "refseq_name": "calmodulin regulator protein PCP4", "refseq_ac": "NP_001071604", "gene_names_uniprotkb": "PCP4", "gene_names_refseq": "PCP4", "protein_names_uniprotkb": "Calmodulin regulator protein PCP4; Purkinje cell protein 4", "protein_names_refseq": "brain-specific antigen PCP-4; calmodulin regulator protein PCP4", "tax_id": 9913, "disease": "", "pathway": " (bta:768324)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Functions as a modulator of calcium-binding by calmodulin. Thereby, regulates calmodulin activity and the different processes it controls. For instance, may play a role in neuronal differentiation through activation of calmodulin-dependent kinase signaling pathways., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005516 calmodulin binding;GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0032991 protein-containing complex", "go_biological_process": "GO:0045666 positive regulation of neuron differentiation;GO:1905291 positive regulation of CAMKK-AMPK signaling cascade", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q148C4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q148E1-1", "uniprot_id": "COA8_BOVIN", "mass": 22911.0, "length": 192, "protein_name": "Cytochrome c oxidase assembly factor 8", "gene_name": "COA8", "organism": "Bovine", "refseq_name": "cytochrome c oxidase assembly factor 8", "refseq_ac": "NP_001069927", "gene_names_uniprotkb": "COA8; APOP1; APOPT1", "gene_names_refseq": "APOP-1; APOPT1; C14orf153; C21H14orf153; COA8", "protein_names_uniprotkb": "Cytochrome c oxidase assembly factor 8; APOP-1; Apoptogenic protein 1, mitochondrial; COA8", "protein_names_refseq": "UPF0671 protein C14orf153 homolog; apoptogenic 1, mitochondrial; apoptogenic protein 1, mitochondrial; cytochrome c oxidase assembly factor 8", "tax_id": 9913, "disease": "", "pathway": " (bta:617441)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Required for cytochrome c complex (COX) IV assembly and function Protects COX assembly from oxidation-induced degradation, COX being the terminal component of the mitochondrial respiratory chain., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005739 mitochondrion;GO:0099617 matrix side of mitochondrial inner membrane", "go_biological_process": "GO:0050821 protein stabilization;GO:0000302 response to reactive oxygen species;GO:0097193 intrinsic apoptotic signaling pathway;GO:0033617 mitochondrial respiratory chain complex IV assembly", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q148E1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q148F8-1", "uniprot_id": "HSPB6_BOVIN", "mass": 17469.0, "length": 164, "protein_name": "Heat shock protein beta-6", "gene_name": "HSPB6", "organism": "Bovine", "refseq_name": "heat shock protein beta-6", "refseq_ac": "NP_001069495", "gene_names_uniprotkb": "HSPB6", "gene_names_refseq": "HSP20; HSPB6", "protein_names_uniprotkb": "Heat shock protein beta-6; HspB6", "protein_names_refseq": "heat shock protein beta-6; heat shock protein, alpha-crystallin-related, B6", "tax_id": 9913, "disease": "", "pathway": " (bta:534551)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "10196226;12842460;15722443", "class_list": "", "function": "HSP20 is associated with both actin and alpha-actinin; activation of cyclic nucleotide-dependent signaling pathways leads to increases in the phosphorylation of HSP20 and a decrease in the association of HSP20 with alpha-actinin., [RefSeq, PubMed]; Small heat shock protein which functions as a molecular chaperone probably maintaining denatured proteins in a folding-competent state. Seems to have versatile functions in various biological processes. Plays a role in regulating muscle function such as smooth muscle vasorelaxation and cardiac myocyte contractility. May regulate myocardial angiogenesis implicating KDR. Overexpression mediates cardioprotection and angiogenesis after induced damage. Stabilizes monomeric YWHAZ thereby supporting YWHAZ chaperone-like activity., [UniProtKB, UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A1A4M7", "ec_number_list": "", "go_molecular_function": "GO:0042803 protein homodimerization activity;GO:0051082 unfolded protein binding;GO:0005212 structural constituent of eye lens", "go_cellular_component": "GO:0005576 extracellular region;GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0043066 negative regulation of apoptotic process;GO:0009408 response to heat;GO:0042026 protein refolding", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q148F8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q148G5-1", "uniprot_id": "PROD_BOVIN", "mass": 67080.0, "length": 593, "protein_name": "Proline dehydrogenase 1, mitochondrial", "gene_name": "PRODH", "organism": "Bovine", "refseq_name": "proline dehydrogenase 1, mitochondrial", "refseq_ac": "NP_001068653", "gene_names_uniprotkb": "PRODH", "gene_names_refseq": "PRODH", "protein_names_uniprotkb": "Proline dehydrogenase 1, mitochondrial; 1.5.5.2; Proline oxidase", "protein_names_refseq": "proline dehydrogenase (oxidase) 1; proline dehydrogenase 1, mitochondrial; proline oxidase", "tax_id": 9913, "disease": "", "pathway": " (bta:505094)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Converts proline to delta-1-pyrroline-5-carboxylate., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.5.5.3;1.5.5.2", "go_molecular_function": "GO:0071949 FAD binding;GO:0004657 proline dehydrogenase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0010133 L-proline catabolic process to L-glutamate", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q148G5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q148H5-1", "uniprot_id": "K2C71_BOVIN", "mass": 57408.0, "length": 525, "protein_name": "Keratin, type II cytoskeletal 71", "gene_name": "KRT71", "organism": "Bovine", "refseq_name": "keratin, type II cytoskeletal 71", "refseq_ac": "NP_001069438", "gene_names_uniprotkb": "KRT71", "gene_names_refseq": "KRT71", "protein_names_uniprotkb": "Keratin, type II cytoskeletal 71; CK-71; Cytokeratin-71; K71; Keratin-71; Type II inner root sheath-specific keratin-K6irs1; Type-II keratin Kb34", "protein_names_refseq": "CK-71; K71; cytokeratin-71; keratin, type II cytoskeletal 71; type II inner root sheath-specific keratin-K6irs1; type-II keratin Kb34", "tax_id": 9913, "disease": "", "pathway": " (bta:532644)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "34356054", "class_list": "", "function": "A KRT71 Loss-of-Function Variant Results in Inner Root Sheath Dysplasia and Recessive Congenital Hypotrichosis of Hereford Cattle. Publication Status: Online-Only, [RefSeq, PubMed]; Plays a central role in hair formation. Essential component of keratin intermediate filaments in the inner root sheath (IRS) of the hair follicle., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0030280 structural constituent of skin epidermis", "go_cellular_component": "GO:0045095 keratin filament", "go_biological_process": "GO:0031424 keratinization;GO:0045109 intermediate filament organization;GO:0031069 hair follicle morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q148H5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q148K0-1", "uniprot_id": "TCEA2_BOVIN", "mass": 33642.0, "length": 300, "protein_name": "Transcription elongation factor A protein 2", "gene_name": "TCEA2", "organism": "Bovine", "refseq_name": "transcription elongation factor A protein 2", "refseq_ac": "NP_001068797", "gene_names_uniprotkb": "TCEA2", "gene_names_refseq": "TCEA2", "protein_names_uniprotkb": "Transcription elongation factor A protein 2; Transcription elongation factor S-II protein 2", "protein_names_refseq": "transcription elongation factor A (SII), 2; transcription elongation factor A protein 2; transcription elongation factor S-II protein 2", "tax_id": 9913, "disease": "", "pathway": " (bta:507729)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0003711 transcription elongation factor activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006368 transcription elongation by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q148K0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q148K5-1", "uniprot_id": "PX11B_BOVIN", "mass": 28278.0, "length": 258, "protein_name": "Peroxisomal membrane protein 11B", "gene_name": "PEX11B", "organism": "Bovine", "refseq_name": "peroxisomal membrane protein 11B", "refseq_ac": "NP_001068734", "gene_names_uniprotkb": "PEX11B", "gene_names_refseq": "PEX11B", "protein_names_uniprotkb": "Peroxisomal membrane protein 11B; Peroxin-11B; Peroxisomal biogenesis factor 11B", "protein_names_refseq": "peroxin-11B; peroxisomal biogenesis factor 11B; peroxisomal membrane protein 11B", "tax_id": 9913, "disease": "", "pathway": " (bta:506527); (R-BTA-9603798)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Involved in peroxisomal proliferation. May regulate peroxisome division by recruiting the dynamin-related GTPase DNM1L to the peroxisomal membrane. Promotes membrane protrusion and elongation on the peroxisomal surface., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005778 peroxisomal membrane", "go_biological_process": "GO:0016559 peroxisome fission", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q148K5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q148L6-1", "uniprot_id": "DHDH_BOVIN", "mass": 36583.0, "length": 335, "protein_name": "Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase", "gene_name": "DHDH", "organism": "Bovine", "refseq_name": "trans-1,2-dihydrobenzene-1,2-diol dehydrogenase", "refseq_ac": "NP_001069937", "gene_names_uniprotkb": "DHDH", "gene_names_refseq": "DHDH", "protein_names_uniprotkb": "Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase; 1.1.1.-; 1.1.1.115; 1.1.1.119; 1.1.1.120; 1.1.1.179; 1.3.1.20; D-arabinose 1-dehydrogenase; D-galactose 1-dehydrogenase; D-glucose 1-dehydrogenase; D-ribose 1-dehydrogenase; D-xylose 1-dehydrogenase; D-xylose-NADP dehydrogenase; Dimeric dihydrodiol dehydrogenase", "protein_names_refseq": "D-xylose 1-dehydrogenase; D-xylose-NADP dehydrogenase; dihydrodiol dehydrogenase (dimeric); dimeric dihydrodiol dehydrogenase; putative LOC617564 protein; trans-1,2-dihydrobenzene-1,2-diol dehydrogenase", "tax_id": 9913, "disease": "", "pathway": " (bta:617564)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalyzes the NADP(+)-linked oxidation of trans-dihydrodiols of aromatic hydrocarbons to the corresponding catechols. It also catalyzes the oxidation of several pentoses and hexoses. In the reverse reaction in the presence of NADPH, it acts as NADPH-linked reductase on a broad range of substrates including aldehydes, chetones, and alpha-dicarbonyl compounds such as 3-deoxyglucosone, camphorquinone and methylglyoxal., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.1.1.31;1.1.1.47;1.1.1.363;1.3.1.20;1.1.1.179;1.1.1.-;1.1.1.115;1.1.1.119;1.1.1.120", "go_molecular_function": "GO:0000166 nucleotide binding;GO:0047115 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity;GO:0047837 D-xylose 1-dehydrogenase (NADP+) activity", "go_cellular_component": "", "go_biological_process": "GO:0042843 D-xylose catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q148L6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q148M8-1", "uniprot_id": "ABT1_BOVIN", "mass": 31160.0, "length": 275, "protein_name": "Activator of basal transcription 1", "gene_name": "ABT1", "organism": "Bovine", "refseq_name": "activator of basal transcription 1", "refseq_ac": "NP_001069620", "gene_names_uniprotkb": "ABT1", "gene_names_refseq": "ABT1", "protein_names_uniprotkb": "Activator of basal transcription 1", "protein_names_refseq": "activator of basal transcription 1", "tax_id": 9913, "disease": "", "pathway": " (bta:539270)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Could be a novel TATA-binding protein (TBP) which can function as a basal transcription activator. Can act as a regulator of basal transcription for class II genes (By similarity)., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0003723 RNA binding", "go_cellular_component": "GO:0005730 nucleolus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006355 regulation of DNA-templated transcription;GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0000472 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q148M8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q17Q89-1", "uniprot_id": "PFD6_BOVIN", "mass": 14555.0, "length": 129, "protein_name": "Prefoldin subunit 6", "gene_name": "PFDN6", "organism": "Bovine", "refseq_name": "prefoldin subunit 6", "refseq_ac": "NP_001068889", "gene_names_uniprotkb": "PFDN6", "gene_names_refseq": "PFDN6", "protein_names_uniprotkb": "Prefoldin subunit 6", "protein_names_refseq": "prefoldin subunit 6", "tax_id": 9913, "disease": "", "pathway": " (bta:509914)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "30573663", "class_list": "", "function": "Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0051082 unfolded protein binding;GO:0051087 protein-folding chaperone binding;GO:0001540 amyloid-beta binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0016272 prefoldin complex", "go_biological_process": "GO:0006457 protein folding;GO:0051131 chaperone-mediated protein complex assembly;GO:1905907 negative regulation of amyloid fibril formation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q17Q89-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q17QB7-1", "uniprot_id": "RAB30_BOVIN", "mass": 23058.0, "length": 203, "protein_name": "Ras-related protein Rab-30", "gene_name": "RAB30", "organism": "Bovine", "refseq_name": "ras-related protein Rab-30", "refseq_ac": "NP_001069697", "gene_names_uniprotkb": "RAB30", "gene_names_refseq": "RAB30", "protein_names_uniprotkb": "Ras-related protein Rab-30; 3.6.5.2", "protein_names_refseq": "ras-related protein Rab-30", "tax_id": 9913, "disease": "", "pathway": " (bta:540583); (R-BTA-6811438); (R-BTA-8873719)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB30 is required for maintaining the structural integrity of the Golgi apparatus, possibly by mediating interactions with cytoplasmic scaffolding proteins (By similarity). Facilitates lipid homeostasis during fasting by regulating hepatic protein and lipid trafficking in a PPAR-alpha-dependent manner (By similarity). Promotes autophagosome biogenesis during bacterial infection such as group A Streptococcus infection (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.6.5.2;3.6.5.5;3.6.5.-;3.6.5.3;2.7.11.1;3.6.1.5;3.6.1.15;3.6.5.4;2.5.1.60", "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0046872 metal ion binding;GO:0003925 G protein activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0000421 autophagosome membrane;GO:0031410 cytoplasmic vesicle;GO:0005801 cis-Golgi network;GO:0005802 trans-Golgi network", "go_biological_process": "GO:0055088 lipid homeostasis;GO:0016192 vesicle-mediated transport;GO:0007030 Golgi organization;GO:0032482 Rab protein signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q17QB7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q17QD3-1", "uniprot_id": "RFOX1_BOVIN", "mass": 38175.0, "length": 355, "protein_name": "RNA binding protein fox-1 homolog 1", "gene_name": "RBFOX1", "organism": "Bovine", "refseq_name": "RNA binding protein fox-1 homolog 1", "refseq_ac": "NP_001069286", "gene_names_uniprotkb": "RBFOX1; A2BP1; FOX1", "gene_names_refseq": "A2BP1; FOX1; RBFOX1", "protein_names_uniprotkb": "RNA binding protein fox-1 homolog 1; Ataxin-2-binding protein 1; Fox-1 homolog A", "protein_names_refseq": "RNA binding protein fox-1 homolog 1; RNA binding protein, fox-1 homolog 1; ataxin 2-binding protein 1; fox-1 homolog A", "tax_id": 9913, "disease": "", "pathway": " (bta:521304)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "RNA-binding protein that regulates alternative splicing events by binding to 5'-UGCAUGU-3' elements. Prevents binding of U2AF2 to the 3'-splice site. Regulates alternative splicing of tissue-specific exons and of differentially spliced exons during erythropoiesis (By similarity)., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003729 mRNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006397 mRNA processing;GO:0007399 nervous system development;GO:0008380 RNA splicing;GO:0000381 regulation of alternative mRNA splicing, via spliceosome", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q17QD3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q17QF2-1", "uniprot_id": "EFMT1_BOVIN", "mass": 25495.0, "length": 226, "protein_name": "EEF1A lysine methyltransferase 1", "gene_name": "EEF1AKMT1", "organism": "Bovine", "refseq_name": "EEF1A lysine methyltransferase 1", "refseq_ac": "NP_001073818", "gene_names_uniprotkb": "EEF1AKMT1; N6AMT2", "gene_names_refseq": "EEF1AKMT1; N6AMT2", "protein_names_uniprotkb": "EEF1A lysine methyltransferase 1; 2.1.1.-; N(6)-adenine-specific DNA methyltransferase 2; Protein-lysine N-methyltransferase N6AMT2", "protein_names_refseq": "EEF1A lysine methyltransferase 1; N-6 adenine-specific DNA methyltransferase 2 (putative); eukaryotic translation elongation factor 1 alpha lysine methyltransferase 1; n(6)-adenine-specific DNA methyltransferase 2; protein-lysine N-methyltransferase N6AMT2", "tax_id": 9913, "disease": "", "pathway": " (bta:783374)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at 'Lys-79'., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.1.1.359;2.1.1.372;2.1.1.-", "go_molecular_function": "GO:0003676 nucleic acid binding;GO:0008168 methyltransferase activity;GO:0016279 protein-lysine N-methyltransferase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0018022 peptidyl-lysine methylation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q17QF2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q17QF8-1", "uniprot_id": "SCAM5_BOVIN", "mass": 26116.0, "length": 235, "protein_name": "Secretory carrier-associated membrane protein 5", "gene_name": "SCAMP5", "organism": "Bovine", "refseq_name": "secretory carrier-associated membrane protein 5", "refseq_ac": "NP_001160037", "gene_names_uniprotkb": "SCAMP5", "gene_names_refseq": "SCAMP5", "protein_names_uniprotkb": "Secretory carrier-associated membrane protein 5; Secretory carrier membrane protein 5", "protein_names_refseq": "secretory carrier-associated membrane protein 5", "tax_id": 9913, "disease": "", "pathway": " (bta:508510)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Required for the calcium-dependent exocytosis of signal sequence-containing cytokines such as CCL5. Probably acts in cooperation with the SNARE machinery (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005886 plasma membrane;GO:0032588 trans-Golgi network membrane;GO:0055038 recycling endosome membrane;GO:0030672 synaptic vesicle membrane", "go_biological_process": "GO:0015031 protein transport;GO:0001819 positive regulation of cytokine production;GO:0006887 exocytosis;GO:0045956 positive regulation of calcium ion-dependent exocytosis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q17QF8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q17QH7-1", "uniprot_id": "TFPT_BOVIN", "mass": 28096.0, "length": 251, "protein_name": "TCF3 fusion partner homolog", "gene_name": "TFPT", "organism": "Bovine", "refseq_name": "TCF3 fusion partner homolog", "refseq_ac": "NP_001068742", "gene_names_uniprotkb": "TFPT", "gene_names_refseq": "TFPT", "protein_names_uniprotkb": "TCF3 fusion partner homolog", "protein_names_refseq": "TCF3 (E2A) fusion partner (in childhood Leukemia); TCF3 fusion partner homolog", "tax_id": 9913, "disease": "", "pathway": " (bta:506610); (R-BTA-5689603); (R-BTA-5696394)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Appears to promote apoptosis in a p53/TP53-independent manner., [UniProtKB]; Putative regulatory component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0019901 protein kinase binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0031011 Ino80 complex", "go_biological_process": "GO:0060382 regulation of DNA strand elongation;GO:0006281 DNA repair;GO:0006310 DNA recombination;GO:0006338 chromatin remodeling;GO:0006351 DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q17QH7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q17QI2-1", "uniprot_id": "SSU72_BOVIN", "mass": 22588.0, "length": 194, "protein_name": "RNA polymerase II subunit A C-terminal domain phosphatase SSU72", "gene_name": "SSU72", "organism": "Bovine", "refseq_name": "RNA polymerase II subunit A C-terminal domain phosphatase SSU72", "refseq_ac": "NP_001069817", "gene_names_uniprotkb": "SSU72", "gene_names_refseq": "SSU72", "protein_names_uniprotkb": "RNA polymerase II subunit A C-terminal domain phosphatase SSU72; 3.1.3.16; CTD phosphatase SSU72", "protein_names_refseq": "CTD phosphatase SSU72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72; SSU72 RNA polymerase II CTD phosphatase homolog", "tax_id": 9913, "disease": "", "pathway": " (bta:614837); (R-BTA-6807505)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Protein phosphatase that catalyzes the dephosphorylation of the C-terminal domain of RNA polymerase II. Plays a role in RNA processing and termination. Plays a role in pre-mRNA polyadenylation via its interaction with SYMPK (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.1.3.16;3.1.3.48;3.1.3.67;3.1.13.-;2.7.7.48;2.7.7.6;3.1.3.74;2.3.1.48;3.1.3.52;3.1.3.53;2.7.11.22;2.7.11.23", "go_molecular_function": "GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005847 mRNA cleavage and polyadenylation specificity factor complex", "go_biological_process": "GO:0006369 termination of RNA polymerase II transcription;GO:0180010 co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q17QI2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q17QI7-1", "uniprot_id": "S2539_BOVIN", "mass": 39148.0, "length": 359, "protein_name": "Mitochondrial glutathione transporter SLC25A39", "gene_name": "SLC25A39", "organism": "Bovine", "refseq_name": "mitochondrial glutathione transporter SLC25A39", "refseq_ac": "NP_001068883", "gene_names_uniprotkb": "SLC25A39", "gene_names_refseq": "SLC25A39", "protein_names_uniprotkb": "Mitochondrial glutathione transporter SLC25A39; Solute carrier family 25 member 39", "protein_names_refseq": "mitochondrial glutathione transporter SLC25A39; probable mitochondrial glutathione transporter SLC25A39", "tax_id": 9913, "disease": "", "pathway": " (bta:509684)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Mitochondrial transporter required for glutathione import into mitochondria. Glutathione, which plays key roles in oxidative metabolism, is produced exclusively in the cytosol and is imported in many organelles. Mitochondrial glutathione is required for the activity and stability of proteins containing iron-sulfur clusters, as well as erythropoiesis., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0046872 metal ion binding;GO:0051537 2 iron, 2 sulfur cluster binding;GO:0034634 glutathione transmembrane transporter activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0071281 cellular response to iron ion;GO:0006783 heme biosynthetic process;GO:1990542 mitochondrial transmembrane transport;GO:0160007 glutathione import into mitochondrion", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q17QI7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q17QI8-1", "uniprot_id": "RHOV_BOVIN", "mass": 25971.0, "length": 236, "protein_name": "Rho-related GTP-binding protein RhoV", "gene_name": "Rhov", "organism": "Bovine", "refseq_name": "rho-related GTP-binding protein RhoV", "refseq_ac": "NP_001069567", "gene_names_uniprotkb": "Rhov", "gene_names_refseq": "RHOV", "protein_names_uniprotkb": "Rho-related GTP-binding protein RhoV; 3.6.5.2", "protein_names_refseq": "ras homolog gene family, member V; rho-related GTP-binding protein RhoV", "tax_id": 9913, "disease": "", "pathway": " (bta:538143); (R-BTA-9013424)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Plays a role in the control of the actin cytoskeleton via activation of the JNK pathway., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.6.5.2;2.7.11.1;3.6.5.5;3.4.19.12;3.6.5.-;3.6.5.3;2.3.2.27;2.7.10.1;3.6.1.5;2.7.11.25;3.6.1.15;3.6.5.4", "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0019901 protein kinase binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0010008 endosome membrane", "go_biological_process": "GO:0006897 endocytosis;GO:0007015 actin filament organization;GO:0007165 signal transduction;GO:0007264 small GTPase-mediated signal transduction;GO:0008360 regulation of cell shape", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q17QI8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q17QK8-1", "uniprot_id": "SPRE_BOVIN", "mass": 28939.0, "length": 267, "protein_name": "Sepiapterin reductase", "gene_name": "SPR", "organism": "Bovine", "refseq_name": "sepiapterin reductase", "refseq_ac": "NP_001069471", "gene_names_uniprotkb": "SPR", "gene_names_refseq": "SPR", "protein_names_uniprotkb": "Sepiapterin reductase; 1.1.1.153; SPR", "protein_names_refseq": "7,8-dihydrobiopterin:NADP+ oxidoreductase; sepiapterin reductase", "tax_id": 9913, "disease": "", "pathway": " (bta:533836)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "19429835", "class_list": "", "function": "Catalyzes the final one or two reductions in tetra-hydrobiopterin biosynthesis to form 5,6,7,8-tetrahydrobiopterin., [UniProtKB]; This study demonstrates an important role of endothelial SPR in modulating tetrahydrobiopterin and nitric oxide bioavailability, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A7YKV0", "ec_number_list": "1.1.1.153", "go_molecular_function": "GO:0004757 sepiapterin reductase (NADP+) activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0006729 tetrahydrobiopterin biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q17QK8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q17QM8-1", "uniprot_id": "DUS14_BOVIN", "mass": 22237.0, "length": 198, "protein_name": "Dual specificity protein phosphatase 14", "gene_name": "DUSP14", "organism": "Bovine", "refseq_name": "dual specificity protein phosphatase 14", "refseq_ac": "NP_001068776", "gene_names_uniprotkb": "DUSP14", "gene_names_refseq": "DUSP14", "protein_names_uniprotkb": "Dual specificity protein phosphatase 14; 3.1.3.16; 3.1.3.48", "protein_names_refseq": "dual specificity protein phosphatase 14", "tax_id": 9913, "disease": "", "pathway": " (bta:507294)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Involved in the inactivation of MAP kinases. Dephosphorylates ERK, JNK and p38 MAP-kinases. Plays a negative role in TCR signaling by dephosphorylating MAP3K7 adapter TAB1 leading to its inactivation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.1.3.48;3.1.3.16;3.1.3.2;3.1.3.67;3.1.3.21;3.1.3.5;3.1.3.74;3.1.3.52;3.1.3.18;3.1.3.53", "go_molecular_function": "GO:0004722 protein serine/threonine phosphatase activity;GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity;GO:0004725 protein tyrosine phosphatase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q17QM8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q17QN0-1", "uniprot_id": "CHIN_BOVIN", "mass": 38247.0, "length": 334, "protein_name": "N-chimaerin", "gene_name": "CHN1", "organism": "Bovine", "refseq_name": "N-chimaerin isoform 1", "refseq_ac": "NP_001068817", "gene_names_uniprotkb": "CHN1; ARHGAP2; CHN", "gene_names_refseq": "CHN1", "protein_names_uniprotkb": "N-chimaerin; A-chimaerin; Alpha-chimerin; N-chimerin; NC; Rho GTPase-activating protein 2", "protein_names_refseq": "A-chimaerin; N-chimaerin isoform 1; N-chimaerin; N-chimerin; NC; alpha-chimerin; chimerin (chimaerin) 1; rho GTPase-activating protein 2", "tax_id": 9913, "disease": "", "pathway": " (bta:508266)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "22095607;27898966", "class_list": "", "function": "Association between a single nucleotide polymorphism in the bovine chemerin gene and carcass traits Publication Status: Online-Only, [RefSeq, PubMed]; GTPase-activating protein for p21-rac and a phorbol ester receptor. Involved in the assembly of neuronal locomotor circuits as a direct effector of EPHA4 in axon guidance (By similarity)., [UniProtKB]; These data indicate that as a consequence of weaning, which causes physiological stress and alters hepatic metabolism, chemerin protein expression within the liver is downregulated, indicating that chemerin plays a role in the upregulation of hepatic expression via its inhibitory effect on hepatic gluconeogenesis., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005096 GTPase activator activity;GO:0008270 zinc ion binding", "go_cellular_component": "", "go_biological_process": "GO:0050770 regulation of axonogenesis;GO:0048013 ephrin receptor signaling pathway;GO:0008045 motor neuron axon guidance", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q17QN0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q17QQ1-1", "uniprot_id": "LTOR3_BOVIN", "mass": 13650.0, "length": 124, "protein_name": "Ragulator complex protein LAMTOR3", "gene_name": "LAMTOR3", "organism": "Bovine", "refseq_name": "ragulator complex protein LAMTOR3", "refseq_ac": "NP_001069450", "gene_names_uniprotkb": "LAMTOR3", "gene_names_refseq": "LAMTOR3; MAP2K1IP1; MAPKSP1", "protein_names_uniprotkb": "Ragulator complex protein LAMTOR3; Late endosomal/lysosomal adaptor and MAPK and MTOR activator 3", "protein_names_refseq": "MAPK scaffold protein 1; late endosomal/lysosomal adaptor and MAPK and MTOR activator 3; mitogen-activated protein kinase kinase 1 interacting protein 1; mitogen-activated protein kinase scaffold protein 1; ragulator complex protein LAMTOR3", "tax_id": 9913, "disease": "", "pathway": " (bta:533155); (R-BTA-1632852); (R-BTA-165159); (R-BTA-166208); (R-BTA-380972); (R-BTA-5628897); (R-BTA-5674135); (R-BTA-6798695); (R-BTA-8943724); (R-BTA-9639288)", "pathway_count": 10, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V-ATPase, the Ragulator plays a dual role for the small GTPases Rag (RagA/RRAGA, RagB/RRAGB, RagC/RRAGC and/or RagD/RRAGD): it (1) acts as a guanine nucleotide exchange factor (GEF), activating the small GTPases Rag and (2) mediates recruitment of Rag GTPases to the lysosome membrane. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated (By similarity). Adapter protein that enhances the efficiency of the MAP kinase cascade facilitating the activation of MAPK2 (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005765 lysosomal membrane;GO:0031902 late endosome membrane;GO:0071986 Ragulator complex", "go_biological_process": "GO:1904263 positive regulation of TORC1 signaling;GO:0032008 positive regulation of TOR signaling;GO:0008104 intracellular protein localization;GO:0071230 cellular response to amino acid stimulus", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q17QQ1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q17QQ4-1", "uniprot_id": "TAF9_BOVIN", "mass": 28800.0, "length": 264, "protein_name": "Transcription initiation factor TFIID subunit 9", "gene_name": "TAF9", "organism": "Bovine", "refseq_name": "transcription initiation factor TFIID subunit 9", "refseq_ac": "NP_001069443", "gene_names_uniprotkb": "TAF9", "gene_names_refseq": "TAF9", "protein_names_uniprotkb": "Transcription initiation factor TFIID subunit 9", "protein_names_refseq": "TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa; TAFII-31; transcription initiation factor TFIID 31 kDa subunit; transcription initiation factor TFIID subunit 9", "tax_id": 9913, "disease": "", "pathway": " (bta:532936); (R-BTA-674695); (R-BTA-6804756); (R-BTA-6807505); (R-BTA-73776); (R-BTA-73779); (R-BTA-75953); (R-BTA-76042)", "pathway_count": 8, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "The TFIID basal transcription factor complex plays a major role in the initiation of RNA polymerase II (Pol II)-dependent transcription. TFIID recognizes and binds promoters with or without a TATA box via its subunit TBP, a TATA-box-binding protein, and promotes assembly of the pre-initiation complex (PIC). The TFIID complex consists of TBP and TBP-associated factors (TAFs), including TAF1, TAF2, TAF3, TAF4, TAF5, TAF6, TAF7, TAF8, TAF9, TAF10, TAF11, TAF12 and TAF13. TAF9 is also a component of the TBP-free TAFII complex (TFTC), the PCAF histone acetylase complex and the STAGA transcription coactivator-HAT complex. TAF9 and its paralog TAF9B are involved in transcriptional activation as well as repression of distinct but overlapping sets of genes. Essential for cell viability. May have a role in gene regulation associated with apoptosis., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 10, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003713 transcription coactivator activity;GO:0046982 protein heterodimerization activity;GO:0051117 ATPase binding;GO:0000976 transcription cis-regulatory region binding;GO:0002039 p53 binding", "go_cellular_component": "GO:0033276 transcription factor TFTC complex;GO:0071339 MLL1 complex;GO:0070761 pre-snoRNP complex;GO:0005669 transcription factor TFIID complex;GO:0000124 SAGA complex", "go_biological_process": "GO:0060261 positive regulation of transcription initiation by RNA polymerase II;GO:0060760 positive regulation of response to cytokine stimulus;GO:0043066 negative regulation of apoptotic process;GO:0050821 protein stabilization;GO:0070555 response to interleukin-1", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q17QQ4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q17QR6-1", "uniprot_id": "MOT13_BOVIN", "mass": 44713.0, "length": 426, "protein_name": "Monocarboxylate transporter 13", "gene_name": "SLC16A13", "organism": "Bovine", "refseq_name": "monocarboxylate transporter 13", "refseq_ac": "NP_001069600", "gene_names_uniprotkb": "SLC16A13; MCT13", "gene_names_refseq": "MCT13; SLC16A13", "protein_names_uniprotkb": "Monocarboxylate transporter 13; MCT 13; Solute carrier family 16 member 13", "protein_names_refseq": "MCT 13; monocarboxylate transporter 13; solute carrier family 16, member 13 (monocarboxylic acid transporter 13)", "tax_id": 9913, "disease": "", "pathway": " (bta:538855)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Proton-linked monocarboxylate transporter. May catalyze the transport of monocarboxylates across the plasma membrane., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0015293 symporter activity;GO:0008028 monocarboxylic acid transmembrane transporter activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005794 Golgi apparatus;GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q17QR6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q17QR7-1", "uniprot_id": "ZN691_BOVIN", "mass": 32004.0, "length": 282, "protein_name": "Zinc finger protein 691", "gene_name": "ZNF691", "organism": "Bovine", "refseq_name": "zinc finger protein 691", "refseq_ac": "NP_001069430", "gene_names_uniprotkb": "ZNF691", "gene_names_refseq": "ZNF691", "protein_names_uniprotkb": "Zinc finger protein 691", "protein_names_refseq": "zinc finger protein 691", "tax_id": 9913, "disease": "", "pathway": " (bta:532460)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "May be involved in transcriptional regulation., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q17QR7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q17QR8-1", "uniprot_id": "HARB1_BOVIN", "mass": 39003.0, "length": 349, "protein_name": "Putative nuclease HARBI1", "gene_name": "HARBI1", "organism": "Bovine", "refseq_name": "putative nuclease HARBI1", "refseq_ac": "NP_001069136", "gene_names_uniprotkb": "HARBI1", "gene_names_refseq": "C11orf77; C15H11orf77; HARBI1", "protein_names_uniprotkb": "Putative nuclease HARBI1; 3.1.-.-; Harbinger transposase-derived nuclease", "protein_names_refseq": "harbinger transposase-derived nuclease; putative nuclease HARBI1", "tax_id": 9913, "disease": "", "pathway": " (bta:514442)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15169610", "class_list": "", "function": "Transposase-derived protein that may have nuclease activity (Potential). Does not have transposase activity (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0016787 hydrolase activity;GO:0046872 metal ion binding;GO:0004518 nuclease activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0005886 plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q17QR8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q17QU4-1", "uniprot_id": "RB39B_BOVIN", "mass": 24608.0, "length": 213, "protein_name": "Ras-related protein Rab-39B", "gene_name": "RAB39B", "organism": "Bovine", "refseq_name": "ras-related protein Rab-39B", "refseq_ac": "NP_001069563", "gene_names_uniprotkb": "RAB39B", "gene_names_refseq": "RAB39B", "protein_names_uniprotkb": "Ras-related protein Rab-39B; 3.6.5.2", "protein_names_refseq": "ras-related protein Rab-39B", "tax_id": 9913, "disease": "", "pathway": " (bta:537560); (R-BTA-8873719); (R-BTA-8876198)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB39B is involved in autophagy and may function in autophagosome formation (By similarity). Binds downstream effector PICK1 to ensure selectively GRIA2 exit from the endoplasmic reticulum to the Golgi and to regulate AMPAR composition at the post-synapses and thus synaptic transmission. May regulate the homeostasis of SNCA/alpha-synuclein (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.6.5.2;3.6.5.5;3.6.5.-;3.6.5.3;2.7.11.1;3.6.1.5;3.6.1.15;3.6.5.4;2.5.1.60", "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0046872 metal ion binding;GO:0031489 myosin V binding;GO:0003925 G protein activity", "go_cellular_component": "GO:0000421 autophagosome membrane;GO:0005794 Golgi apparatus;GO:0005886 plasma membrane;GO:0030659 cytoplasmic vesicle membrane;GO:0043005 neuron projection", "go_biological_process": "GO:0010506 regulation of autophagy;GO:0015031 protein transport;GO:0050808 synapse organization;GO:0006914 autophagy;GO:0016192 vesicle-mediated transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q17QU4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q17QV9-1", "uniprot_id": "STK40_BOVIN", "mass": 48929.0, "length": 436, "protein_name": "Serine/threonine-protein kinase 40", "gene_name": "STK40", "organism": "Bovine", "refseq_name": "serine/threonine-protein kinase 40", "refseq_ac": "NP_001069195", "gene_names_uniprotkb": "STK40", "gene_names_refseq": "STK40", "protein_names_uniprotkb": "Serine/threonine-protein kinase 40; 2.7.11.1", "protein_names_refseq": "SINK-homologous serine/threonine kinase; serine/threonine-protein kinase 40", "tax_id": 9913, "disease": "", "pathway": " (bta:515723)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "May be a negative regulator of NF-kappa-B and p53-mediated gene transcription., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.11.1;2.7.11.25;2.7.11.24;2.7.11.22;2.7.11.13;2.7.11.23;2.7.12.1;2.7.12.2;2.7.11.17;2.7.11.39;2.7.10.2;2.7.1.150;2.7.11.12;2.7.11.31;2.7.11.26;2.7.11.21;2.7.1.153;2.7.1.137;2.7.1.154;4.1.1.32;2.7.11.38;2.7.11.11;3.1.11.-;2.7.4.6;2.7.13.3;2.7.4.18;3.1.24.-;2.7.11.-;2.7.11.4;2.7.2.3;2.7.11.10", "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0043408 regulation of MAPK cascade", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q17QV9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q17QW1-1", "uniprot_id": "BORG5_BOVIN", "mass": 37334.0, "length": 361, "protein_name": "Cdc42 effector protein 1", "gene_name": "CDC42EP1", "organism": "Bovine", "refseq_name": "cdc42 effector protein 1", "refseq_ac": "NP_001068963", "gene_names_uniprotkb": "CDC42EP1; BORG5", "gene_names_refseq": "CDC42EP1", "protein_names_uniprotkb": "Cdc42 effector protein 1; Binder of Rho GTPases 5", "protein_names_refseq": "CDC42 effector protein (Rho GTPase binding) 1; binder of Rho GTPases 5; cdc42 effector protein 1", "tax_id": 9913, "disease": "", "pathway": " (bta:511099); (R-BTA-9013404); (R-BTA-9013406); (R-BTA-9013408); (R-BTA-9013423)", "pathway_count": 5, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Probably involved in the organization of the actin cytoskeleton. Induced membrane extensions in fibroblasts (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 18, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0031267 small GTPase binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005856 cytoskeleton;GO:0005886 plasma membrane;GO:0012505 endomembrane system", "go_biological_process": "GO:0007266 Rho protein signal transduction;GO:0008360 regulation of cell shape;GO:0031274 positive regulation of pseudopodium assembly;GO:0030838 positive regulation of actin filament polymerization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q17QW1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q17QX2-1", "uniprot_id": "ZGPAT_BOVIN", "mass": 55285.0, "length": 513, "protein_name": "Zinc finger CCCH-type with G patch domain-containing protein", "gene_name": "ZGPAT", "organism": "Bovine", "refseq_name": "zinc finger CCCH-type with G patch domain-containing protein", "refseq_ac": "NP_001019685", "gene_names_uniprotkb": "ZGPAT", "gene_names_refseq": "ZGPAT", "protein_names_uniprotkb": "Zinc finger CCCH-type with G patch domain-containing protein", "protein_names_refseq": "zinc finger CCCH-type with G patch domain-containing protein; zinc finger, CCCH-type with G patch domain", "tax_id": 9913, "disease": "", "pathway": " (bta:510866)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Transcription repressor that specifically binds the 5'-GGAG[GA]A[GA]A-3' consensus sequence. Represses transcription by recruiting the chromatin multiprotein complex NuRD to target promoters. Negatively regulates expression of EGFR, a gene involved in cell proliferation, survival and migration. Its ability to repress genes of the EGFR pathway suggest it may act as a tumor suppressor (By similarity)., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0008270 zinc ion binding;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0043565 sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0045892 negative regulation of DNA-templated transcription;GO:0007175 negative regulation of epidermal growth factor-activated receptor activity", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q17QX2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q17QX9-1", "uniprot_id": "CWC27_BOVIN", "mass": 54063.0, "length": 473, "protein_name": "Spliceosome-associated protein CWC27 homolog", "gene_name": "CWC27", "organism": "Bovine", "refseq_name": "spliceosome-associated protein CWC27 homolog", "refseq_ac": "NP_001068628", "gene_names_uniprotkb": "CWC27; SDCCAG10", "gene_names_refseq": "CWC27; SDCCAG10", "protein_names_uniprotkb": "Spliceosome-associated protein CWC27 homolog; PPIase CWC27; Probable inactive peptidyl-prolyl cis-trans isomerase CWC27 homolog", "protein_names_refseq": "CWC27 spliceosome associated protein homolog; PPIase CWC27; peptidyl-prolyl cis-trans isomerase CWC27 homolog; peptidyl-prolyl cis-trans isomerase SDCCAG10; probable inactive peptidyl-prolyl cis-trans isomerase CWC27 homolog; serologically defined colon cancer antigen 10; spliceosome-associated protein CWC27 homolog", "tax_id": 9913, "disease": "", "pathway": " (bta:504397)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "As part of the spliceosome, plays a role in pre-mRNA splicing. Probable inactive PPIase with no peptidyl-prolyl cis-trans isomerase activity. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003755 peptidyl-prolyl cis-trans isomerase activity", "go_cellular_component": "GO:0071013 catalytic step 2 spliceosome;GO:0071005 U2-type precatalytic spliceosome", "go_biological_process": "GO:0006457 protein folding", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q17QX9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q17R00-1", "uniprot_id": "EMX2_BOVIN", "mass": 28344.0, "length": 253, "protein_name": "Homeobox protein EMX2", "gene_name": "EMX2", "organism": "Bovine", "refseq_name": "homeobox protein EMX2", "refseq_ac": "NP_001069313", "gene_names_uniprotkb": "EMX2", "gene_names_refseq": "EMX2", "protein_names_uniprotkb": "Homeobox protein EMX2; Empty spiracles homolog 2; Empty spiracles-like protein 2", "protein_names_refseq": "empty spiracles homolog 2; empty spiracles-like protein 2; homeobox protein EMX2", "tax_id": 9913, "disease": "", "pathway": " (bta:523601)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Transcription factor, which in cooperation with EMX1, acts to generate the boundary between the roof and archipallium in the developing brain. May function in combination with OTX1/2 to specify cell fates in the developing central nervous system. In the inner ear, it controls the distribution of GPR156 at hair cell boundaries, and regulates the organization of stereociliary bundles in opposite orientations across the line of polarity reversal (LPR)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0030424 axon", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0007417 central nervous system development;GO:0007420 brain development;GO:0030182 neuron differentiation;GO:0160194 stereocilium bundle organization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q17R00-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q17R16-1", "uniprot_id": "LHPL4_BOVIN", "mass": 27006.0, "length": 247, "protein_name": "LHFPL tetraspan subfamily member 4 protein", "gene_name": "LHFPL4", "organism": "Bovine", "refseq_name": "LHFPL tetraspan subfamily member 4 protein", "refseq_ac": "NP_001069694", "gene_names_uniprotkb": "LHFPL4", "gene_names_refseq": "LHFPL4", "protein_names_uniprotkb": "LHFPL tetraspan subfamily member 4 protein; Lipoma HMGIC fusion partner-like 4 protein", "protein_names_refseq": "LHFPL tetraspan subfamily member 4 protein; lipoma HMGIC fusion partner-like 4 protein", "tax_id": 9913, "disease": "", "pathway": " (bta:540541)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Plays a role in the regulation of inhibitory synapse formation and function by being involved in maintening gamma-aminobutyric acid receptors (GABAARs) clustering and their associated scaffold proteins at inhibitory synaptic sites. Acts in concert with NLGN2 to recruit or stabilize GABAARs., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0050811 GABA receptor binding", "go_cellular_component": "GO:0098982 GABA-ergic synapse;GO:0005886 plasma membrane;GO:0030425 dendrite;GO:0045211 postsynaptic membrane;GO:0060077 inhibitory synapse", "go_biological_process": "GO:0097112 gamma-aminobutyric acid receptor clustering;GO:0007605 sensory perception of sound;GO:1905702 regulation of inhibitory synapse assembly;GO:0099645 neurotransmitter receptor localization to postsynaptic specialization membrane", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q17R16-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q1ECT8-1", "uniprot_id": "UQCC4_BOVIN", "mass": 14832.0, "length": 135, "protein_name": "Ubiquinol-cytochrome c reductase complex assembly factor 4", "gene_name": "UQCC4", "organism": "Bovine", "refseq_name": "ubiquinol-cytochrome c reductase complex assembly factor 4 precursor", "refseq_ac": "NP_001069980", "gene_names_uniprotkb": "UQCC4; CCSMST1", "gene_names_refseq": "C16orf91; C25H16orf91; CCSMST1; UQCC4", "protein_names_uniprotkb": "Ubiquinol-cytochrome c reductase complex assembly factor 4; Cattle cerebrum and skeletal muscle-specific protein 1; Protein CCSMST1", "protein_names_refseq": "cattle cerebrum and skeletal muscle-specific protein 1; cerebrum and skeletal muscle specific transcript 1; chromosome 25 C16orf91 homolog; protein CCSMST1; ubiquinol-cytochrome c reductase complex assembly factor 4 precursor", "tax_id": 9913, "disease": "", "pathway": " (bta:618598)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "16554549", "class_list": "", "function": "Required for the assembly and stability of the mitochondrial ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain (ETC) which drives oxidative phosphorylation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0022904 respiratory electron transport chain;GO:0034551 mitochondrial respiratory chain complex III assembly", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q1ECT8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q1JPA3-1", "uniprot_id": "TMM47_BOVIN", "mass": 19998.0, "length": 181, "protein_name": "Transmembrane protein 47", "gene_name": "TMEM47", "organism": "Bovine", "refseq_name": "transmembrane protein 47", "refseq_ac": "NP_001069730", "gene_names_uniprotkb": "TMEM47; TM4SF10", "gene_names_refseq": "TMEM47", "protein_names_uniprotkb": "Transmembrane protein 47; Transmembrane 4 superfamily member 10", "protein_names_refseq": "transmembrane 4 superfamily member 10; transmembrane protein 47", "tax_id": 9913, "disease": "", "pathway": " (bta:541164)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "Regulates cell junction organization in epithelial cells. May play a role in the transition from adherens junction to tight junction assembly. May regulate F-actin polymerization required for tight junctional localization dynamics and affect the junctional localization of PARD6B. During podocyte differentiation may negatively regulate activity of FYN and subsequently the abundance of nephrin (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005911 cell-cell junction;GO:0005912 adherens junction", "go_biological_process": "GO:0098609 cell-cell adhesion", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q1JPA3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q1JPD8-1", "uniprot_id": "S43A3_BOVIN", "mass": 54424.0, "length": 489, "protein_name": "Equilibrative nucleobase transporter 1", "gene_name": "SLC43A3", "organism": "Bovine", "refseq_name": "equilibrative nucleobase transporter 1", "refseq_ac": "NP_001033215", "gene_names_uniprotkb": "SLC43A3; ENBT1", "gene_names_refseq": "SLC43A3", "protein_names_uniprotkb": "Equilibrative nucleobase transporter 1; Solute carrier family 43 member 3", "protein_names_refseq": "equilibrative nucleobase transporter 1", "tax_id": 9913, "disease": "", "pathway": " (bta:516840)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "Sodium-independent purine-selective nucleobase transporter which mediates the equilibrative transport of extracellular purine nucleobases such as adenine, guanine and hypoxanthine (By similarity). May regulate fatty acid (FA) transport in adipocytes, acting as a positive regulator of FA efflux and as a negative regulator of FA uptake (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q2T9X4", "ec_number_list": "", "go_molecular_function": "GO:0015245 fatty acid transmembrane transporter activity;GO:0042910 xenobiotic transmembrane transporter activity;GO:0015207 adenine transmembrane transporter activity;GO:0015208 guanine transmembrane transporter activity", "go_cellular_component": "GO:0016323 basolateral plasma membrane", "go_biological_process": "GO:0035344 hypoxanthine transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q1JPD8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q1JPJ8-1", "uniprot_id": "THOP1_BOVIN", "mass": 78139.0, "length": 687, "protein_name": "Thimet oligopeptidase", "gene_name": "THOP1", "organism": "Bovine", "refseq_name": "thimet oligopeptidase", "refseq_ac": "NP_001029163", "gene_names_uniprotkb": "THOP1", "gene_names_refseq": "THOP1", "protein_names_uniprotkb": "Thimet oligopeptidase; 3.4.24.15", "protein_names_refseq": "endopeptidase EC3.4.24.15; thimet oligopeptidase", "tax_id": 9913, "disease": "", "pathway": " (bta:510889)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "14726412;16305752;23708739", "class_list": "", "function": "Cyclic strain putatively regulates both the mRNA expression and enzymatic function of EP24.15 and EP24.16., [RefSeq, PubMed]; Involved in the metabolism of neuropeptides under 20 amino acid residues long (By similarity). Involved in cytoplasmic peptide degradation. Able to degrade the amyloid-beta precursor protein and generate amyloidogenic fragments (By similarity). Also acts as a regulator of cannabinoid signaling pathway by mediating degradation of hemopressin, an antagonist peptide of the cannabinoid receptor CNR1 (By similarity)., [UniProtKB, UniProtKB, UniProtKB]; Shear-dependent TOP induction down-regulates MHC1 levels, pointing to a role for TOP in the flow-mediated regulation of endothelial immunogenicity, [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A6QQT3", "ec_number_list": "", "go_molecular_function": "GO:0004222 metalloendopeptidase activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005758 mitochondrial intermembrane space", "go_biological_process": "GO:0006508 proteolysis", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q1JPJ8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q1JPJ9-1", "uniprot_id": "EF2KT_BOVIN", "mass": 37952.0, "length": 340, "protein_name": "Protein-lysine N-methyltransferase EEF2KMT", "gene_name": "EEF2KMT", "organism": "Bovine", "refseq_name": "protein-lysine N-methyltransferase EEF2KMT", "refseq_ac": "NP_001157410", "gene_names_uniprotkb": "EEF2KMT; FAM86A", "gene_names_refseq": "EEF2KMT; FAM86A; eEF2-KMT", "protein_names_uniprotkb": "Protein-lysine N-methyltransferase EEF2KMT; 2.1.1.-; eEF2-KMT; eEF2-lysine methyltransferase", "protein_names_refseq": "eEF2-lysine methyltransferase; family with sequence similarity 86, member A; protein FAM86A; protein-lysine N-methyltransferase EEF2KMT; putative protein N-methyltransferase FAM86A", "tax_id": 9913, "disease": "", "pathway": " (bta:531984); (R-BTA-8876725)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "Catalyzes the trimethylation of eukaryotic elongation factor 2 (EEF2) on 'Lys-525'., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.1.1.359;2.1.1.372;2.1.1.-;3.6.5.-", "go_molecular_function": "GO:0016279 protein-lysine N-methyltransferase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0032991 protein-containing complex", "go_biological_process": "GO:0018023 peptidyl-lysine trimethylation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q1JPJ9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q1JQ99-1", "uniprot_id": "RM14_BOVIN", "mass": 15916.0, "length": 145, "protein_name": "Large ribosomal subunit protein uL14m", "gene_name": "MRPL14", "organism": "Bovine", "refseq_name": "large ribosomal subunit protein uL14m precursor", "refseq_ac": "NP_001069805", "gene_names_uniprotkb": "MRPL14", "gene_names_refseq": "MRPL14", "protein_names_uniprotkb": "Large ribosomal subunit protein uL14m; 39S ribosomal protein L14, mitochondrial; L14mt; MRP-L14", "protein_names_refseq": "39S ribosomal protein L14, mitochondrial; L14mt; MRP-L14; large ribosomal subunit protein uL14m precursor; large ribosomal subunit protein uL14m", "tax_id": 9913, "disease": "", "pathway": " (bta:614579)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "11279069", "class_list": "", "function": "May form part of 2 intersubunit bridges in the assembled ribosome. Upon binding to MALSU1, intersubunit bridge formation is blocked, preventing ribosome formation and repressing translation., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005762 mitochondrial large ribosomal subunit;GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0006412 translation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q1JQ99-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q1JQB3-1", "uniprot_id": "GPR4_BOVIN", "mass": 41076.0, "length": 362, "protein_name": "G protein-coupled receptor 4", "gene_name": "GPR4", "organism": "Bovine", "refseq_name": "G-protein coupled receptor 4", "refseq_ac": "NP_001069051", "gene_names_uniprotkb": "GPR4", "gene_names_refseq": "GPR4", "protein_names_uniprotkb": "G protein-coupled receptor 4", "protein_names_refseq": "G-protein coupled receptor 4", "tax_id": 9913, "disease": "", "pathway": " (bta:512876); (R-BTA-373076); (R-BTA-416476)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Proton-sensing G protein-coupled receptor activated by extracellular pH, which is required to monitor pH changes and generate adaptive reactions. Activated by an optimal pH of 6.8-7.2. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors, such as adenylate cyclase. GPR4 is mainly coupled to G(s) G proteins and mediates activation of adenylate cyclase activity. May also couple with G(i), G(q) and G(12)/G(13) G proteins (By similarity). Acts as a key regulator of respiratory sensitivity to CO2/H(+) in brain retrotrapezoid nucleus neurons: acts by mediating detection of protons generated by the formation of carbonic acid in the blood, an important mechanism to impulse to breathe (By similarity). Also acts as a regulator of acid secretion in the kidney collecting duct by maintaining acid-base homeostasis in the kidney. Acidosis-induced GPR4 activation increases paracellular gap formation and permeability of vascular endothelial cells, possibly through the G(12)/G(13)/Rho GTPase signaling pathway (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004930 G protein-coupled receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0030155 regulation of cell adhesion;GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway;GO:0043114 regulation of vascular permeability;GO:0050729 positive regulation of inflammatory response", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q1JQB3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q1JQB5-1", "uniprot_id": "FBLI1_BOVIN", "mass": 41497.0, "length": 378, "protein_name": "Filamin-binding LIM protein 1", "gene_name": "FBLIM1", "organism": "Bovine", "refseq_name": "filamin-binding LIM protein 1", "refseq_ac": "NP_001070423", "gene_names_uniprotkb": "FBLIM1", "gene_names_refseq": "FBLIM1", "protein_names_uniprotkb": "Filamin-binding LIM protein 1; FBLP-1", "protein_names_refseq": "CSX-associated LIM; FBLP-1; filamin-binding LIM protein 1; migfilin", "tax_id": 9913, "disease": "", "pathway": " (bta:767833); (R-BTA-446353)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Serves as an anchoring site for cell-ECM adhesion proteins and filamin-containing actin filaments. Is implicated in cell shape modulation (spreading) and motility. May participate in the regulation of filamin-mediated cross-linking and stabilization of actin filaments. May also regulate the assembly of filamin-containing signaling complexes that control actin assembly. Promotes dissociation of FLNA from ITGB3 and ITGB7. Promotes activation of integrins and regulates integrin-mediated cell-cell adhesion (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0046872 metal ion binding;GO:0031005 filamin binding", "go_cellular_component": "GO:0005925 focal adhesion;GO:0001725 stress fiber", "go_biological_process": "GO:0033623 regulation of integrin activation;GO:0098609 cell-cell adhesion;GO:0008360 regulation of cell shape", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q1JQB5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q1LZ75-1", "uniprot_id": "ERCC1_BOVIN", "mass": 32544.0, "length": 294, "protein_name": "DNA excision repair protein ERCC-1", "gene_name": "ERCC1", "organism": "Bovine", "refseq_name": "DNA excision repair protein ERCC-1", "refseq_ac": "NP_001069853", "gene_names_uniprotkb": "ERCC1", "gene_names_refseq": "ERCC1", "protein_names_uniprotkb": "DNA excision repair protein ERCC-1", "protein_names_refseq": "DNA excision repair protein ERCC-1; excision repair cross-complementing 1; excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)", "tax_id": 9913, "disease": "", "pathway": " (bta:615637); (R-BTA-5685938); (R-BTA-5696395); (R-BTA-5696400); (R-BTA-6782135); (R-BTA-6783310)", "pathway_count": 6, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Non-catalytic component of a structure-specific DNA repair endonuclease responsible for the 5'-incision during DNA repair. Responsible, in conjunction with SLX4, for the first step in the repair of interstrand cross-links (ICL). Participates in the processing of anaphase bridge-generating DNA structures, which consist in incompletely processed DNA lesions arising during S or G2 phase, and can result in cytokinesis failure. Also required for homology-directed repair (HDR) of DNA double-strand breaks, in conjunction with SLX4 (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003684 damaged DNA binding;GO:0003697 single-stranded DNA binding", "go_cellular_component": "GO:0000110 nucleotide-excision repair factor 1 complex;GO:0070522 ERCC4-ERCC1 complex;GO:0000109 nucleotide-excision repair complex;GO:0000781 chromosome, telomeric region", "go_biological_process": "GO:0006312 mitotic recombination;GO:0032205 negative regulation of telomere maintenance;GO:0006979 response to oxidative stress;GO:0000723 telomere maintenance;GO:0006302 double-strand break repair", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q1LZ75-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q1LZ78-1", "uniprot_id": "NTPCR_BOVIN", "mass": 20682.0, "length": 190, "protein_name": "Cancer-related nucleoside-triphosphatase homolog", "gene_name": "NTPCR", "organism": "Bovine", "refseq_name": "cancer-related nucleoside-triphosphatase homolog", "refseq_ac": "NP_001069284", "gene_names_uniprotkb": "NTPCR", "gene_names_refseq": "C1orf57; C28H1orf57; NTPCR", "protein_names_uniprotkb": "Cancer-related nucleoside-triphosphatase homolog; 3.6.1.15; NTPase; Nucleoside triphosphate phosphohydrolase", "protein_names_refseq": "NTPase; UPF0334 kinase-like protein C1orf57; cancer-related nucleoside-triphosphatase homolog; nucleoside triphosphate phosphohydrolase; nucleoside-triphosphatase C1orf57 homolog", "tax_id": 9913, "disease": "", "pathway": " (bta:521103)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. Hydrolyzes nucleoside diphosphates with lower efficiency., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.6.5.2;3.6.4.12;5.6.2.4;3.6.4.13;2.3.2.27;7.2.2.-;2.7.7.7;2.7.7.49;3.6.1.5;3.6.5.5;3.6.4.6;3.6.4.10;5.6.2.3;3.6.5.-;3.6.5.3;5.6.2.-;2.7.4.3;3.6.4.-;2.7.11.1;3.1.-.-;4.2.99.18;5.6.1.6;3.6.1.15;7.6.2.1;3.1.3.1;3.9.1.1;5.6.2.5;3.4.24.-;3.6.-.-;3.6.1.-;5.6.1.7;3.6.5.4;3.1.4.-;3.4.21.53", "go_molecular_function": "GO:0003924 GTPase activity;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0017111 ribonucleoside triphosphate phosphatase activity;GO:0043273 CTPase activity", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q1LZ78-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q1LZ80-1", "uniprot_id": "PAGR1_BOVIN", "mass": 27784.0, "length": 253, "protein_name": "PAXIP1-associated glutamate-rich protein 1", "gene_name": "PAGR1", "organism": "Bovine", "refseq_name": "PAXIP1-associated glutamate-rich protein 1", "refseq_ac": "NP_001069100", "gene_names_uniprotkb": "PAGR1; PA1", "gene_names_refseq": "C16orf53; C25H16orf53; PA1; PAGR1", "protein_names_uniprotkb": "PAXIP1-associated glutamate-rich protein 1; PAXIP1-associated protein 1; PTIP-associated protein 1", "protein_names_refseq": "PAXIP1-associated glutamate-rich protein 1; PAXIP1-associated protein 1; PTIP-associated protein 1", "tax_id": 9913, "disease": "", "pathway": " (bta:513650); (R-BTA-9772755); (R-BTA-9818564)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Its association with the histone methyltransferase MLL2/MLL3 complex is suggesting a role in epigenetic transcriptional activation. However, in association with PAXIP1/PTIP is proposed to function at least in part independently of the MLL2/MLL3 complex. Proposed to be recruited by PAXIP1 to sites of DNA damage where the PAGR1:PAXIP1 complex is required for cell survival in response to DNA damage independently of the MLL2/MLL3 complex. However, its function in DNA damage has been questioned. During immunoglobulin class switching in activated B-cells is involved in transcription regulation of downstream switch regions at the immunoglobulin heavy-chain (Igh) locus independently of the MLL2/MLL3 complex. Involved in both estrogen receptor-regulated gene transcription and estrogen-stimulated G1/S cell-cycle transition. Acts as a transcriptional cofactor for nuclear hormone receptors. Inhibits the induction properties of several steroid receptors such as NR3C1, AR and PPARG; the mechanism of inhibition appears to be gene-dependent., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A4FV67", "ec_number_list": "", "go_molecular_function": "GO:0030331 nuclear estrogen receptor binding", "go_cellular_component": "GO:0044666 MLL3/4 complex", "go_biological_process": "GO:0006281 DNA repair;GO:0006310 DNA recombination;GO:0006351 DNA-templated transcription;GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway;GO:1902808 positive regulation of cell cycle G1/S phase transition", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q1LZ80-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q1LZ87-1", "uniprot_id": "ZN397_BOVIN", "mass": 61277.0, "length": 534, "protein_name": "Zinc finger protein 397", "gene_name": "ZNF397", "organism": "Bovine", "refseq_name": "zinc finger protein 397", "refseq_ac": "NP_001068730", "gene_names_uniprotkb": "ZNF397", "gene_names_refseq": "ZNF397", "protein_names_uniprotkb": "Zinc finger protein 397", "protein_names_refseq": "zinc finger protein 397", "tax_id": 9913, "disease": "", "pathway": " (bta:506448)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "DNA-dependent transcriptional repressor., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005730 nucleolus;GO:0005829 cytosol;GO:0015630 microtubule cytoskeleton", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0045892 negative regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q1LZ87-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q1LZA0-1", "uniprot_id": "PIGB_BOVIN", "mass": 63591.0, "length": 541, "protein_name": "GPI alpha-1,2-mannosyltransferase 3", "gene_name": "PIGB", "organism": "Bovine", "refseq_name": "GPI alpha-1,2-mannosyltransferase 3", "refseq_ac": "NP_001071523", "gene_names_uniprotkb": "PIGB", "gene_names_refseq": "PIGB", "protein_names_uniprotkb": "GPI alpha-1,2-mannosyltransferase 3; 2.4.1.-; GPI mannosyltransferase III; GPI-MT-III; PIG-B; Phosphatidylinositol-glycan biosynthesis class B protein", "protein_names_refseq": "GPI alpha-1,2-mannosyltransferase 3; GPI mannosyltransferase 3; GPI mannosyltransferase III; GPI-MT-III; PIG-B; phosphatidylinositol-glycan biosynthesis class B protein", "tax_id": 9913, "disease": "", "pathway": " (bta:616044); (R-BTA-162710)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Alpha-1,2-mannosyltransferase that catalyzes the transfer of the third mannose, via an alpha-1,2 bond, from a dolichol-phosphate-mannose (Dol-P-Man) to a 2-acyl-6-[alpha-D-mannosyl-(1->6)-2-phosphoethanolamine-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl]-1-(1-radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositol intermediate to generate a 2-acyl-6-[alpha-D-mannosyl-(1->2)-alpha-D-mannosyl-(1->6)-2-phosphoethanolamine-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl]-1-(1-radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositol (also termed H6) and participates in the nineth step of the glycosylphosphatidylinositol-anchor biosynthesis (By similarity). May also add the third mannose to a 2-acyl-6-[alpha-D-mannosyl-(1->6)-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl]-1-(1-radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositol (also termed H3) intermediate generating a 2-acyl-6-(alpha-D-mannosyl-(1->2)-alpha-D-mannosyl-(1->6)-alpha-D-mannosyl-(1->4)-alpha-D-glucosaminyl)-1-(1-radyl,2-acyl-sn-glycero-3-phospho)-1D-myo-inositol (also termed H4) (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.4.1.-", "go_molecular_function": "GO:0000026 alpha-1,2-mannosyltransferase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006506 GPI anchor biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q1LZA0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q1LZA4-1", "uniprot_id": "PIGW_BOVIN", "mass": 56298.0, "length": 503, "protein_name": "Glucosaminyl-phosphatidylinositol-acyltransferase PIGW", "gene_name": "PIGW", "organism": "Bovine", "refseq_name": "glucosaminyl-phosphatidylinositol- acyltransferase PIGW", "refseq_ac": "NP_001070577", "gene_names_uniprotkb": "PIGW", "gene_names_refseq": "PIG-W; PIGW", "protein_names_uniprotkb": "Glucosaminyl-phosphatidylinositol-acyltransferase PIGW; 2.3.-.-; GlcN-PI-acyltransferase; PIG-W; Phosphatidylinositol-glycan biosynthesis class W protein", "protein_names_refseq": "glcN-PI-acyltransferase; glucosaminyl-phosphatidylinositol- acyltransferase PIGW; phosphatidylinositol glycan, class W; phosphatidylinositol-glycan biosynthesis class W protein", "tax_id": 9913, "disease": "", "pathway": " (bta:768052)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Acyltransferase that catalyzes the acyl transfer from an acyl-CoA at the 2-OH position of the inositol ring of a 6-(alpha-D-glucosaminyl)-1-(1,2-diacyl-sn-glycero-3-phospho)-1D-myo-inositol (glucosaminyl phosphatidylinositol, GlcN-PI) to generate a 2-acyl-6-alpha-D-glucosaminyl-1-(1,2-diacyl-sn-glycero-3-phospho)-1D-myo-inositol (glucosaminyl acyl phosphatidylinositol, GlcN-(acyl)PI) and participates in the fourth step of GPI-anchor biosynthesis (By similarity). Required for the transport of GPI-anchored proteins to the plasma membrane (By similarity). Acylation during GPI-anchor biosynthesis is not essential for the subsequent mannosylation and is usually removed soon after the attachment of GPIs to proteins (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.3.-.-", "go_molecular_function": "GO:0032216 glucosaminyl-phosphatidylinositol O-acyltransferase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0072659 protein localization to plasma membrane;GO:0006506 GPI anchor biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q1LZA4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q1LZA7-1", "uniprot_id": "LIMD2_BOVIN", "mass": 14144.0, "length": 128, "protein_name": "LIM domain-containing protein 2", "gene_name": "LIMD2", "organism": "Bovine", "refseq_name": "LIM domain-containing protein 2", "refseq_ac": "NP_001035602", "gene_names_uniprotkb": "LIMD2", "gene_names_refseq": "LIMD2", "protein_names_uniprotkb": "LIM domain-containing protein 2", "protein_names_refseq": "LIM domain-containing protein 2", "tax_id": 9913, "disease": "", "pathway": " (bta:508942)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Acts as an activator of the protein-kinase ILK, thereby regulating cell motility., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0046872 metal ion binding;GO:0051015 actin filament binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0015629 actin cytoskeleton", "go_biological_process": "GO:0051017 actin filament bundle assembly", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q1LZA7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q1LZB4-1", "uniprot_id": "IFT46_BOVIN", "mass": 33922.0, "length": 301, "protein_name": "Intraflagellar transport protein 46 homolog", "gene_name": "IFT46", "organism": "Bovine", "refseq_name": "intraflagellar transport protein 46 homolog", "refseq_ac": "NP_001068677", "gene_names_uniprotkb": "IFT46", "gene_names_refseq": "C11orf60; C15H11orf60; IFT46", "protein_names_uniprotkb": "Intraflagellar transport protein 46 homolog", "protein_names_refseq": "intraflagellar transport 46 homolog; intraflagellar transport protein 46 homolog; intraflagellar transport protein IFT46", "tax_id": 9913, "disease": "", "pathway": " (bta:505579); (R-BTA-5620924)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "17720815", "class_list": "", "function": "Characterization of a similar gene in mouse and zebrafish., [RefSeq, PubMed]; Forms part of a complex involved in intraflagellar transport (IFT), the bi-directional movement of particles required for the assembly, maintenance and functioning of primary cilia. May play a role in chondrocyte maturation and skeletogenesis (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0031514 motile cilium;GO:0005815 microtubule organizing center;GO:0030992 intraciliary transport particle B", "go_biological_process": "GO:0060271 cilium assembly;GO:0042073 intraciliary transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q1LZB4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q1LZB9-1", "uniprot_id": "FSTL3_BOVIN", "mass": 27658.0, "length": 261, "protein_name": "Follistatin-related protein 3", "gene_name": "FSTL3", "organism": "Bovine", "refseq_name": "follistatin-related protein 3 precursor", "refseq_ac": "NP_001069178", "gene_names_uniprotkb": "FSTL3", "gene_names_refseq": "FSTL3", "protein_names_uniprotkb": "Follistatin-related protein 3; Follistatin-like protein 3", "protein_names_refseq": "follistatin-like 3 (secreted glycoprotein); follistatin-like protein 3; follistatin-related protein 3 precursor; follistatin-related protein 3", "tax_id": 9913, "disease": "", "pathway": " (bta:515367)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "The secreted form is a binding and antagonizing protein for members of the TGF-beta family, such as activin, BMP2 and MSTN. Inhibits activin A-, activin B-, BMP2- and MSDT-induced cellular signaling; more effective on activin A than on activin B. Involved in bone formation; inhibits osteoclast differentiation. Involved in hematopoiesis; involved in differentiation of hemopoietic progenitor cells, increases hematopoietic cell adhesion to fibronectin and seems to contribute to the adhesion of hematopoietic precursor cells to the bone marrow stroma. The nuclear form is probably involved in transcriptional regulation via interaction with MLLT10 (By similarity)., [UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005634 nucleus;GO:0031012 extracellular matrix", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0001503 ossification", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q1LZB9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q1LZC0-1", "uniprot_id": "ZNF22_BOVIN", "mass": 26077.0, "length": 225, "protein_name": "Zinc finger protein 22", "gene_name": "ZNF22", "organism": "Bovine", "refseq_name": "zinc finger protein 22", "refseq_ac": "NP_001070576", "gene_names_uniprotkb": "ZNF22", "gene_names_refseq": "ZNF22", "protein_names_uniprotkb": "Zinc finger protein 22", "protein_names_refseq": "zinc finger protein 22 (KOX 15); zinc finger protein 22", "tax_id": 9913, "disease": "", "pathway": " (bta:768051)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Binds DNA through the consensus sequence 5'-CAATG-3'. May be involved in transcriptional regulation and may play a role in tooth formation (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005654 nucleoplasm", "go_biological_process": "GO:0006351 DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q1LZC0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q1LZD0-1", "uniprot_id": "AA2BR_BOVIN", "mass": 36385.0, "length": 332, "protein_name": "Adenosine receptor A2b", "gene_name": "ADORA2B", "organism": "Bovine", "refseq_name": "adenosine receptor A2b", "refseq_ac": "NP_001069393", "gene_names_uniprotkb": "ADORA2B", "gene_names_refseq": "ADORA2B", "protein_names_uniprotkb": "Adenosine receptor A2b", "protein_names_refseq": "adenosine receptor A2b", "tax_id": 9913, "disease": "", "pathway": " (bta:529760); (R-BTA-417973); (R-BTA-418555); (R-BTA-5683826)", "pathway_count": 4, "publication_count": 2, "publication_id_list": "18292397;21622845", "class_list": "", "function": "It is likely that adenosine acts through A(2B) receptors and adenylyl cyclases to stimulate CNGA2., [RefSeq, PubMed]; Purinergic stimulation of cilia beat frequency requires A(2B) adenosine receptor activation, likely via protein kinase A-dependent pathway., [RefSeq, PubMed]; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase (By similarity)., [UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0001609 G protein-coupled adenosine receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0042311 vasodilation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q1LZD0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q1LZD3-1", "uniprot_id": "TSSC4_BOVIN", "mass": 33241.0, "length": 325, "protein_name": "U5 small nuclear ribonucleoprotein TSSC4", "gene_name": "TSSC4", "organism": "Bovine", "refseq_name": "U5 small nuclear ribonucleoprotein TSSC4", "refseq_ac": "NP_001068878", "gene_names_uniprotkb": "TSSC4", "gene_names_refseq": "TSSC4", "protein_names_uniprotkb": "U5 small nuclear ribonucleoprotein TSSC4", "protein_names_refseq": "U5 small nuclear ribonucleoprotein TSSC4; protein TSSC4", "tax_id": 9913, "disease": "", "pathway": " (bta:509559)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "26440077", "class_list": "", "function": "Imprinting status of four cattle genes (Tssc4,Nap1l4, Phlda2 and Osbpl5) in seven types of tissues, were assessed in cattle., [RefSeq, PubMed]; Protein associated with the U5 snRNP, during its maturation and its post-splicing recycling and which is required for spliceosomal tri-snRNP complex assembly in the nucleus. Has a molecular sequestering activity and transiently hinders SNRNP200 binding sites for constitutive splicing factors that intervene later during the assembly of the spliceosome and splicing. Together with its molecular sequestering activity, may also function as a molecular adapter and placeholder, coordinating the assembly of the U5 snRNP and its association with the U4/U6 di-snRNP., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 8, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0044877 protein-containing complex binding;GO:0140313 molecular sequestering activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005681 spliceosomal complex;GO:0005682 U5 snRNP", "go_biological_process": "GO:0000244 spliceosomal tri-snRNP complex assembly;GO:0000387 spliceosomal snRNP assembly", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q1LZD3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q1LZE0-1", "uniprot_id": "BRMS1_BOVIN", "mass": 28460.0, "length": 246, "protein_name": "Breast cancer metastasis-suppressor 1 homolog", "gene_name": "BRMS1", "organism": "Bovine", "refseq_name": "breast cancer metastasis-suppressor 1 homolog", "refseq_ac": "NP_001069872", "gene_names_uniprotkb": "BRMS1", "gene_names_refseq": "BRMS1", "protein_names_uniprotkb": "Breast cancer metastasis-suppressor 1 homolog", "protein_names_refseq": "breast cancer metastasis suppressor 1; breast cancer metastasis-suppressor 1 homolog", "tax_id": 9913, "disease": "", "pathway": " (bta:615952); (R-BTA-3214815)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Transcriptional repressor. Down-regulates transcription activation by NF-kappa-B by promoting the deacetylation of RELA at 'Lys-310'. Promotes HDAC1 binding to promoter regions. Down-regulates expression of anti-apoptotic genes that are controlled by NF-kappa-B. Promotes apoptosis in cells that have inadequate adherence to a substrate, a process called anoikis, and may thereby inhibit metastasis (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0042826 histone deacetylase binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0070822 Sin3-type complex", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0006915 apoptotic process;GO:0045892 negative regulation of DNA-templated transcription;GO:0042981 regulation of apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q1LZE0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q1LZE2-1", "uniprot_id": "RHNO1_BOVIN", "mass": 27324.0, "length": 241, "protein_name": "RAD9, HUS1, RAD1-interacting nuclear orphan protein 1", "gene_name": "RHNO1", "organism": "Bovine", "refseq_name": "RAD9, HUS1, RAD1-interacting nuclear orphan protein 1", "refseq_ac": "NP_001069099", "gene_names_uniprotkb": "RHNO1", "gene_names_refseq": "C12orf32; C5H12orf32; RHNO1", "protein_names_uniprotkb": "RAD9, HUS1, RAD1-interacting nuclear orphan protein 1", "protein_names_refseq": "RAD9, HUS1, RAD1-interacting nuclear orphan protein 1; uncharacterized protein C12orf32 homolog", "tax_id": 9913, "disease": "", "pathway": " (bta:513642); (R-BTA-5685938); (R-BTA-5693607); (R-BTA-6804756); (R-BTA-69473)", "pathway_count": 5, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Involved in microhomology-mediated end-joining (MMEJ) DNA repair by promoting recruitment of polymerase theta (POLQ) to DNA damage sites during mitosis. MMEJ is an alternative non-homologous end-joining (NHEJ) machinery that takes place during mitosis to repair double-strand breaks in DNA that originate in S-phase. Accumulates in M-phase; following phosphorylation by PLK1, interacts with POLQ, enabling its recruitment to double-strand breaks for subsequent repair. Also involved in the DNA damage response (DDR) signaling in response to genotoxic stresses such as ionizing radiation (IR) during the S phase. Recruited to sites of DNA damage through interaction with the 9-1-1 cell-cycle checkpoint response complex and TOPBP1 in a ATR-dependent manner. Required for the progression of the G1 to S phase transition. Plays a role in the stimulation of CHEK1 phosphorylation., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0140463 chromatin-protein adaptor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0035861 site of double-strand break;GO:0005694 chromosome", "go_biological_process": "GO:1990166 protein localization to site of double-strand break;GO:0097681 double-strand break repair via alternative nonhomologous end joining;GO:0071479 cellular response to ionizing radiation;GO:0000077 DNA damage checkpoint signaling;GO:0000725 recombinational repair", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q1LZE2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q1LZF8-1", "uniprot_id": "CLCC1_BOVIN", "mass": 61812.0, "length": 542, "protein_name": "Chloride channel CLIC-like protein 1", "gene_name": "CLCC1", "organism": "Bovine", "refseq_name": "chloride channel CLIC-like protein 1 precursor", "refseq_ac": "NP_001069252", "gene_names_uniprotkb": "CLCC1", "gene_names_refseq": "CLCC1; ERAC1", "protein_names_uniprotkb": "Chloride channel CLIC-like protein 1; ER anion channel 1; ERAC1", "protein_names_refseq": "ER anion channel 1; chloride channel CLIC-like protein 1 precursor; chloride channel CLIC-like protein 1", "tax_id": 9913, "disease": "", "pathway": " (bta:519085)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Anion-selective channel with Ca(2+)-dependent and voltage-independent gating. Permeable to small monovalent anions with selectivity for bromide > chloride > nitrate > fluoride (By similarity). Operates in the endoplasmic reticulum (ER) membrane where it mediates chloride efflux to compensate for the loss of positive charges from the ER lumen upon Ca(2+) release. Contributes to the maintenance of ER Ca(2+) pools and activation of unfolded protein response to prevent accumulation of misfolded proteins in the ER lumen. Particularly involved in ER homeostasis mechanisms underlying motor neurons and retinal photoreceptors survival (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "5.6.1.6;1.8.-.-;1.8.5.1", "go_molecular_function": "GO:0005254 chloride channel activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0016020 membrane;GO:0005789 endoplasmic reticulum membrane;GO:0044233 mitochondria-associated endoplasmic reticulum membrane contact site;GO:0034707 chloride channel complex", "go_biological_process": "GO:0032469 endoplasmic reticulum calcium ion homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q1LZF8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q1LZG6-1", "uniprot_id": "CCNB1_BOVIN", "mass": 47658.0, "length": 427, "protein_name": "G2/mitotic-specific cyclin-B1", "gene_name": "CCNB1", "organism": "Bovine", "refseq_name": "G2/mitotic-specific cyclin-B1", "refseq_ac": "NP_001039337", "gene_names_uniprotkb": "CCNB1", "gene_names_refseq": "CCNB1", "protein_names_uniprotkb": "G2/mitotic-specific cyclin-B1", "protein_names_refseq": "G2/mitotic-specific cyclin-B1", "tax_id": 9913, "disease": "", "pathway": " (bta:327679); (R-BTA-174048); (R-BTA-176408); (R-BTA-176412); (R-BTA-176417); (R-BTA-2299718); (R-BTA-2500257); (R-BTA-2565942); (R-BTA-2980767); (R-BTA-2995383); (R-BTA-3301854); (R-BTA-4419969); (R-BTA-6804114); (R-BTA-68875); (R-BTA-69273); (R-BTA-69478); (R-BTA-75035); (R-BTA-8878166)", "pathway_count": 18, "publication_count": 3, "publication_id_list": "15601923;15736128;19602178", "class_list": "", "function": "Cyclin-dependent kinase inhibition did not affect the expression (mRNA and protein levels) and localization of maturation promoting factor(MPF) and MAPK, and had nearly no effect on kinase activities during maturation., [RefSeq, PubMed]; Essential for the control of the cell cycle at the G2/M (mitosis) transition (By similarity). Binds and activates cyclin-dependent protein kinase CDK1/CDC2 (By similarity)., [UniProtKB, UniProtKB]; Link between cytoplasmic polyadenylation of cyclin B1 and translation/appearance of cyclin B1 protein before in vitro maturation of oocytes, [RefSeq, PubMed]; Polyadenylation of cyclin B1 was also completely prevented when 3'-dA was added at 0 hr, and greatly reduced when added at 6 hr, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005813 centrosome;GO:0005815 microtubule organizing center;GO:0097125 cyclin B1-CDK1 complex", "go_biological_process": "GO:0051301 cell division;GO:0000082 G1/S transition of mitotic cell cycle;GO:0007080 mitotic metaphase chromosome alignment", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q1LZG6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q1LZH9-1", "uniprot_id": "GNS_BOVIN", "mass": 62776.0, "length": 560, "protein_name": "N-acetylglucosamine-6-sulfatase", "gene_name": "GNS", "organism": "Bovine", "refseq_name": "N-acetylglucosamine-6-sulfatase precursor", "refseq_ac": "NP_001069030", "gene_names_uniprotkb": "GNS", "gene_names_refseq": "G6S; GNS", "protein_names_uniprotkb": "N-acetylglucosamine-6-sulfatase; 3.1.6.14; G6S; Glucosamine-6-sulfatase", "protein_names_refseq": "N-acetylglucosamine-6-sulfatase precursor; N-acetylglucosamine-6-sulfatase; glucosamine (N-acetyl)-6-sulfatase (Sanfilippo disease IIID); glucosamine-6-sulfatase", "tax_id": 9913, "disease": "", "pathway": " (bta:512444)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Hydrolyzes 6-sulfate groups in N-acetyl-d-glucosaminide units of heparin sulfate and keratan sulfate., [UniProtKB, UniProtKB]", "predicted_glycosites": 13, "predicted_n_glycosites": 13, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 13, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008449 N-acetylglucosamine-6-sulfatase activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005764 lysosome", "go_biological_process": "GO:0030203 glycosaminoglycan metabolic process;GO:0030200 heparan sulfate proteoglycan catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q1LZH9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q1LZI1-1", "uniprot_id": "UD3A1_BOVIN", "mass": 59682.0, "length": 523, "protein_name": "UDP-glycosyltransferase 3A1", "gene_name": "UGT3A1", "organism": "Bovine", "refseq_name": "UDP-glucuronosyltransferase 3A1 precursor", "refseq_ac": "NP_001069555", "gene_names_uniprotkb": "UGT3A1", "gene_names_refseq": "UGT3A1; UGT3A2", "protein_names_uniprotkb": "UDP-glycosyltransferase 3A1; 2.4.1.170; UDP-glucosyltransferase 3A1; UDPGT 3A1", "protein_names_refseq": "UDP glycosyltransferase 3 family, polypeptide A1; UDP-glucuronosyltransferase 3A1 precursor; UDP-glucuronosyltransferase 3A1-like; UDP-glucuronosyltransferase 3A1; UDPGT 3A1", "tax_id": 9913, "disease": "", "pathway": " (bta:537188)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Involved in biotransformation reactions in which lipophilic substrates are conjugated with sugars to increase water solubility and enhance excretion. Such reactions are of major importance in the elimination of potentially toxic xenobiotics and endogenous compounds. It catalyzes the transfer of sugar from UDP-glucose to the bile acid ursodeoxycholic acid (UDCA), while is inactive with UDP-N-acetylglucosamine as sugar donor (By similarity). Is also inactive with UDP-glucuronic acid (By similarity). In addition to UDCA, it can use 4-methylumbelliferone as sugar acceptor (By similarity). To a lesser extent, is able to transfer the sugar residue to 17alpha-estradiol, 17beta-estradiol, 4-nitrophenol, 1-naphtol and genistein. Has negligible activity, if any, toward cholic acid, chenodeoxycholic acid, deoxycholic acid, lithocholic acid, and hyodeoxycholic acid (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.4.1.170", "go_molecular_function": "GO:0015020 glucuronosyltransferase activity", "go_cellular_component": "GO:0043541 UDP-N-acetylglucosamine transferase complex", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q1LZI1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q1RMG8-1", "uniprot_id": "RPAC2_BOVIN", "mass": 15182.0, "length": 133, "protein_name": "DNA-directed RNA polymerases I and III subunit RPAC2", "gene_name": "POLR1D", "organism": "Bovine", "refseq_name": "DNA-directed RNA polymerases I and III subunit RPAC2 isoform 2", "refseq_ac": "NP_001069612", "gene_names_uniprotkb": "POLR1D", "gene_names_refseq": "POLR1D", "protein_names_uniprotkb": "DNA-directed RNA polymerases I and III subunit RPAC2; DNA-directed RNA polymerase I subunit D; RNA polymerases I and III subunit AC2", "protein_names_refseq": "DNA-directed RNA polymerase I subunit D; DNA-directed RNA polymerases I and III subunit RPAC2 isoform 2; DNA-directed RNA polymerases I and III subunit RPAC2; RNA polymerases I and III subunit AC2; polymerase (RNA) I polypeptide D, 16kDa", "tax_id": 9913, "disease": "", "pathway": " (bta:539061)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I and III which synthesize ribosomal RNA precursor pre-rRNA and short non-coding RNAs including 5S rRNA, snRNAs, tRNAs and miRNAs, respectively., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0046983 protein dimerization activity;GO:0003899 DNA-directed RNA polymerase activity", "go_cellular_component": "GO:0005736 RNA polymerase I complex;GO:0005666 RNA polymerase III complex", "go_biological_process": "GO:0006362 transcription elongation by RNA polymerase I;GO:0006383 transcription by RNA polymerase III", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q1RMG8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q1RMH9-1", "uniprot_id": "DNJC2_BOVIN", "mass": 71786.0, "length": 621, "protein_name": "DnaJ homolog subfamily C member 2", "gene_name": "DNAJC2", "organism": "Bovine", "refseq_name": "dnaJ homolog subfamily C member 2", "refseq_ac": "NP_001068805", "gene_names_uniprotkb": "DNAJC2; ZRF1", "gene_names_refseq": "DNAJC2; ZRF1", "protein_names_uniprotkb": "DnaJ homolog subfamily C member 2; Zuotin-related factor 1", "protein_names_refseq": "DnaJ (Hsp40) homolog, subfamily C, member 2; dnaJ homolog subfamily C member 2; zuotin related factor 1", "tax_id": 9913, "disease": "", "pathway": " (bta:507897); (R-BTA-3371453)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Acts both as a chaperone in the cytosol and as a chromatin regulator in the nucleus. When cytosolic, acts as a molecular chaperone: component of the ribosome-associated complex (RAC), a complex involved in folding or maintaining nascent polypeptides in a folding-competent state. In the RAC complex, stimulates the ATPase activity of the ribosome-associated pool of Hsp70-type chaperones HSPA14 that bind to the nascent polypeptide chain. When nuclear, mediates the switching from polycomb-repressed genes to an active state: specifically recruited at histone H2A ubiquitinated at 'Lys-119' (H2AK119ub), and promotes the displacement of the polycomb PRC1 complex from chromatin, thereby facilitating transcription activation., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0061649 ubiquitin-modified histone reader activity;GO:0003682 chromatin binding;GO:0042393 histone binding;GO:0043022 ribosome binding;GO:0030544 Hsp70 protein binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol", "go_biological_process": "GO:0051083 'de novo' cotranslational protein folding;GO:0006351 DNA-templated transcription;GO:0045893 positive regulation of DNA-templated transcription;GO:0006450 regulation of translational fidelity", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q1RMH9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q1RMJ9-1", "uniprot_id": "UCN3_BOVIN", "mass": 17849.0, "length": 166, "protein_name": "Urocortin-3", "gene_name": "UCN3", "organism": "Bovine", "refseq_name": "urocortin-3 precursor", "refseq_ac": "NP_001069995", "gene_names_uniprotkb": "UCN3; SPC", "gene_names_refseq": "UCN3", "protein_names_uniprotkb": "Urocortin-3; Ucn III; Urocortin III", "protein_names_refseq": "ucn III; urocortin 3 (stresscopin); urocortin III; urocortin-3 precursor", "tax_id": 9913, "disease": "", "pathway": " (bta:751573); (R-BTA-373080)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Hormone that plays a central role in whole body adaptation to stress (By similarity). Released by the hypothalamus primarily in response to physical or psychological stress and acts by binding to CRH receptor CRHR2 (By similarity). UCN3-dependent signaling plays a key role in the metabolic regulation and energy homeostasis in responses to stress, acting as an anxiolytic (By similarity). Promotes energy balance by reducing food intake, improving insulin sensitivity and managing blood glucose levels in response to metabolic stress (By similarity). In contrast to CRH and UCN, does not activate the hypothalamus-pituitary-adrenal axis to promote corticotropin hormone (ACTH) production (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0051429 corticotropin-releasing hormone receptor binding;GO:0005179 hormone activity;GO:0051431 corticotropin-releasing hormone receptor 2 binding", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0009755 hormone-mediated signaling pathway;GO:0007586 digestion;GO:0031669 cellular response to nutrient levels", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q1RMJ9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q1RMK9-1", "uniprot_id": "F174B_BOVIN", "mass": 16654.0, "length": 159, "protein_name": "Membrane protein FAM174B", "gene_name": "FAM174B", "organism": "Bovine", "refseq_name": "membrane protein FAM174B precursor", "refseq_ac": "NP_001069818", "gene_names_uniprotkb": "FAM174B", "gene_names_refseq": "FAM174B", "protein_names_uniprotkb": "Membrane protein FAM174B", "protein_names_refseq": "membrane protein FAM174B precursor; membrane protein FAM174B", "tax_id": 9913, "disease": "", "pathway": " (bta:614841)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Essential for Golgi structural integrity., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0005886 plasma membrane", "go_biological_process": "GO:0007030 Golgi organization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q1RMK9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q1RMM1-1", "uniprot_id": "ZC3HF_BOVIN", "mass": 48527.0, "length": 426, "protein_name": "Zinc finger CCCH domain-containing protein 15", "gene_name": "ZC3H15", "organism": "Bovine", "refseq_name": "zinc finger CCCH domain-containing protein 15", "refseq_ac": "NP_001039859", "gene_names_uniprotkb": "ZC3H15", "gene_names_refseq": "ZC3H15", "protein_names_uniprotkb": "Zinc finger CCCH domain-containing protein 15", "protein_names_refseq": "erythropoietin 4 immediate early response-like; zinc finger CCCH domain-containing protein 15", "tax_id": 9913, "disease": "", "pathway": " (bta:535102); (R-BTA-9629569)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Protects DRG1 from proteolytic degradation., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol", "go_biological_process": "GO:0002181 cytoplasmic translation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q1RMM1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q1RMP0-1", "uniprot_id": "RPA12_BOVIN", "mass": 13505.0, "length": 123, "protein_name": "DNA-directed RNA polymerase I subunit RPA12", "gene_name": "POLR1H", "organism": "Bovine", "refseq_name": "DNA-directed RNA polymerase I subunit RPA12", "refseq_ac": "NP_001039865", "gene_names_uniprotkb": "POLR1H", "gene_names_refseq": "POLR1H; ZNRD1", "protein_names_uniprotkb": "DNA-directed RNA polymerase I subunit RPA12; DNA-directed RNA polymerase I subunit H", "protein_names_refseq": "DNA-directed RNA polymerase I subunit H; DNA-directed RNA polymerase I subunit RPA12; zinc ribbon domain containing 1; zinc ribbon domain-containing protein 1", "tax_id": 9913, "disease": "", "pathway": " (bta:535288); (R-BTA-5250924); (R-BTA-73762); (R-BTA-73772); (R-BTA-73863)", "pathway_count": 5, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Core component of RNA polymerase I (Pol I), a DNA-dependent RNA polymerase which synthesizes ribosomal RNA precursors using the four ribonucleoside triphosphates as substrates. Can mediate Pol I proofreading of the nascent RNA transcript. Anchors into the Pol I active site to monitor transcription fidelity and cleave mis-incorporated 5'-ribonucleotides., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0003676 nucleic acid binding;GO:0003899 DNA-directed RNA polymerase activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005736 RNA polymerase I complex", "go_biological_process": "GO:0006363 termination of RNA polymerase I transcription", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q1RMP0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q1RMQ4-1", "uniprot_id": "LYNX1_BOVIN", "mass": 12552.0, "length": 116, "protein_name": "Ly-6/neurotoxin-like protein 1", "gene_name": "LYNX1", "organism": "Bovine", "refseq_name": "ly-6/neurotoxin-like protein 1 precursor", "refseq_ac": "NP_001039686", "gene_names_uniprotkb": "LYNX1", "gene_names_refseq": "LYNX1", "protein_names_uniprotkb": "Ly-6/neurotoxin-like protein 1", "protein_names_refseq": "ly-6/neurotoxin-like protein 1 precursor; ly-6/neurotoxin-like protein 1", "tax_id": 9913, "disease": "", "pathway": " (bta:516158)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Acts in different tissues through interaction to nicotinic acetylcholine receptors (nAChRs). The proposed role as modulator of nAChR activity seems to be dependent on the nAChR subtype and stoichiometry, and to involve an effect on nAChR trafficking and its cell surface expression, and on single channel properties of the nAChR inserted in the plasma membrane. Modulates functional properties of nicotinic acetylcholine receptors (nAChRs) to prevent excessive excitation, and hence neurodegeneration. Enhances desensitization by increasing both the rate and extent of desensitization of alpha-4:beta-2-containing nAChRs and slowing recovery from desensitization. Promotes large amplitude ACh-evoked currents through alpha-4:beta-2 nAChRs. Is involved in regulation of the nAChR pentameric assembly in the endoplasmic reticulum. Shifts stoichiometry from high sensitivity alpha-4(2):beta-2(3) to low sensitivity alpha-4(3):beta-2(2) nAChR. In vitro modulates alpha-3:beta-4-containing nAChRs. Reduces cell surface expression of (alpha-3:beta-4)(2):beta-4 and (alpha-3:beta-4)(2):alpha-5 nAChRs suggesting an interaction with nAChR alpha-3(-):(+)beta-4 subunit interfaces and an allosteric mode. Corresponding single channel effects characterized by decreased unitary conductance, altered burst proportions and enhanced desensitization/inactivation seem to depend on nAChR alpha:alpha subunit interfaces and are greater in (alpha-3:beta-2)(2):alpha-3 when compared to (alpha-3:beta-2)(2):alpha-5 nAChRs. Prevents plasticity in the primary visual cortex late in life., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0030548 acetylcholine receptor regulator activity;GO:0033130 acetylcholine receptor binding;GO:0008200 ion channel inhibitor activity;GO:0030550 acetylcholine receptor inhibitor activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005886 plasma membrane;GO:0030425 dendrite;GO:0045202 synapse;GO:0098552 side of membrane", "go_biological_process": "GO:0095500 acetylcholine receptor signaling pathway;GO:0099601 regulation of neurotransmitter receptor activity", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q1RMQ4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q1RMU1-1", "uniprot_id": "RSPO3_BOVIN", "mass": 31057.0, "length": 273, "protein_name": "R-spondin-3", "gene_name": "RSPO3", "organism": "Bovine", "refseq_name": "R-spondin-3 precursor", "refseq_ac": "NP_001069502", "gene_names_uniprotkb": "RSPO3", "gene_names_refseq": "RSPO3", "protein_names_uniprotkb": "R-spondin-3; Roof plate-specific spondin-3", "protein_names_refseq": "R-spondin 3 homolog; R-spondin-3 precursor; roof plate-specific spondin-3", "tax_id": 9913, "disease": "", "pathway": " (bta:534650); (R-BTA-4641263)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Activator of the canonical Wnt signaling pathway by acting as a ligand for LGR4-6 receptors, which acts as a key regulator of angiogenesis. Upon binding to LGR4-6 (LGR4, LGR5 or LGR6), LGR4-6 associate with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. Also regulates the canonical Wnt/beta-catenin-dependent pathway and non-canonical Wnt signaling by acting as an inhibitor of ZNRF3, an important regulator of the Wnt signaling pathway. Acts as a ligand for frizzled FZD8 and LRP6. May negatively regulate the TGF-beta pathway. Acts as a key regulator of angiogenesis by controlling vascular stability and pruning: acts by activating the non-canonical Wnt signaling pathway in endothelial cells (By similarity). Can also amplify Wnt signaling pathway independently of LGR4-6 receptors, possibly by acting as a direct antagonistic ligand to RNF43 and ZNRF3 (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005109 frizzled binding;GO:0008201 heparin binding", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0001974 blood vessel remodeling;GO:0016055 Wnt signaling pathway;GO:0060173 limb development;GO:0002040 sprouting angiogenesis;GO:0090263 positive regulation of canonical Wnt signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q1RMU1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q1RMU4-1", "uniprot_id": "ERLN2_BOVIN", "mass": 37730.0, "length": 338, "protein_name": "Erlin-2", "gene_name": "ERLIN2", "organism": "Bovine", "refseq_name": "erlin-2", "refseq_ac": "NP_001040041", "gene_names_uniprotkb": "ERLIN2; SPFH2", "gene_names_refseq": "ERLIN2", "protein_names_uniprotkb": "Erlin-2; Endoplasmic reticulum lipid raft-associated protein 2; SPFH domain-containing protein 2; Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2", "protein_names_refseq": "SPFH domain-containing protein 2; endoplasmic reticulum lipid raft-associated protein 2; erlin-2; stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2", "tax_id": 9913, "disease": "", "pathway": " (bta:616278); (R-BTA-382556); (R-BTA-9931269)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs) such as ITPR1. Promotes sterol-accelerated ERAD of HMGCR probably implicating an AMFR/gp78-containing ubiquitin ligase complex. Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway. May promote ER retention of the SCAP-SREBF complex (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0031625 ubiquitin protein ligase binding;GO:0015485 cholesterol binding", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane;GO:0032991 protein-containing complex", "go_biological_process": "GO:0008203 cholesterol metabolic process;GO:0045717 negative regulation of fatty acid biosynthetic process;GO:0045541 negative regulation of cholesterol biosynthetic process;GO:0032933 SREBP signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q1RMU4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q1RMX3-1", "uniprot_id": "B2CL2_BOVIN", "mass": 20774.0, "length": 193, "protein_name": "Bcl-2-like protein 2", "gene_name": "BCL2L2", "organism": "Bovine", "refseq_name": "bcl-2-like protein 2", "refseq_ac": "NP_001070001", "gene_names_uniprotkb": "BCL2L2", "gene_names_refseq": "BCL2L2; RELA", "protein_names_uniprotkb": "Bcl-2-like protein 2; Apoptosis regulator Bcl-W; Bcl2-L-2", "protein_names_refseq": "apoptosis regulator Bcl-W; bcl-2-like protein 2; bcl2-L-2; v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65", "tax_id": 9913, "disease": "", "pathway": " (bta:767601)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "16276654", "class_list": "", "function": "Chromosome mapping of BCL2L2 gene in cows., [RefSeq, PubMed]; Promotes cell survival. Blocks dexamethasone-induced apoptosis. Mediates survival of postmitotic Sertoli cells by suppressing death-promoting activity of BAX (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0015267 channel activity", "go_cellular_component": "GO:0005741 mitochondrial outer membrane;GO:0031966 mitochondrial membrane", "go_biological_process": "GO:0003006 developmental process involved in reproduction;GO:0043065 positive regulation of apoptotic process;GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage;GO:0001836 release of cytochrome c from mitochondria;GO:0097192 extrinsic apoptotic signaling pathway in absence of ligand", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q1RMX3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q1XFL1-1", "uniprot_id": "ZAR1L_BOVIN", "mass": 36053.0, "length": 318, "protein_name": "ZAR1-like protein", "gene_name": "ZAR1L", "organism": "Bovine", "refseq_name": "ZAR1-like protein", "refseq_ac": "NP_001120912", "gene_names_uniprotkb": "ZAR1L", "gene_names_refseq": "ZAR1-LIKE; ZAR1L", "protein_names_uniprotkb": "ZAR1-like protein", "protein_names_refseq": "ZAR1-like protein", "tax_id": 9913, "disease": "", "pathway": " (bta:616037)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "18442940", "class_list": "", "function": "Analysis of the protein primary structure of Zar1-like showed a high conservation of the C-terminal region, where the putative presence of both zinc finger motifs and classical nuclear localization signals is also shared with Zar1., [RefSeq, PubMed]; mRNA-binding protein required for maternal mRNA storage, translation and degradation during oocyte maturation (By similarity). Probably promotes formation of some phase-separated membraneless compartment that stores maternal mRNAs in oocytes: acts by undergoing liquid-liquid phase separation upon binding to maternal mRNAs (By similarity). Binds to the 3'-UTR of maternal mRNAs, inhibiting their translation (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0003730 mRNA 3'-UTR binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0036464 cytoplasmic ribonucleoprotein granule;GO:0043232 intracellular membraneless organelle", "go_biological_process": "GO:0017148 negative regulation of translation;GO:0001556 oocyte maturation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q1XFL1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q24JY1-1", "uniprot_id": "RL23A_BOVIN", "mass": 17695.0, "length": 156, "protein_name": "Large ribosomal subunit protein uL23", "gene_name": "RPL23A", "organism": "Bovine", "refseq_name": "large ribosomal subunit protein uL23", "refseq_ac": "NP_001039423", "gene_names_uniprotkb": "RPL23A", "gene_names_refseq": "RPL23AY; RPL23A", "protein_names_uniprotkb": "Large ribosomal subunit protein uL23; 60S ribosomal protein L23a", "protein_names_refseq": "60S ribosomal protein L23a; large ribosomal subunit protein uL23; ribosomal protein L23a Y-linked protein", "tax_id": 9913, "disease": "", "pathway": " (bta:507168)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. Binds a specific region on the 26S rRNA. May promote p53/TP53 degradation possibly through the stimulation of MDM2-mediated TP53 polyubiquitination., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0019843 rRNA binding;GO:0003735 structural constituent of ribosome;GO:1904841 TORC2 complex binding", "go_cellular_component": "GO:0005634 nucleus;GO:0022625 cytosolic large ribosomal subunit", "go_biological_process": "GO:0006412 translation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q24JY1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q24K00-1", "uniprot_id": "NUBP1_BOVIN", "mass": 34182.0, "length": 320, "protein_name": "Cytosolic Fe-S cluster assembly factor NUBP1", "gene_name": "NUBP1", "organism": "Bovine", "refseq_name": "cytosolic Fe-S cluster assembly factor NUBP1", "refseq_ac": "NP_001068763", "gene_names_uniprotkb": "NUBP1", "gene_names_refseq": "NUBP1", "protein_names_uniprotkb": "Cytosolic Fe-S cluster assembly factor NUBP1; NBP 1; Nucleotide-binding protein 1", "protein_names_refseq": "cytosolic Fe-S cluster assembly factor NUBP1; nucleotide binding protein 1 (MinD homolog, E. coli); nucleotide-binding protein 1", "tax_id": 9913, "disease": "", "pathway": " (bta:507007)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins. Implicated in the regulation of centrosome duplication. Negatively regulates cilium formation and structure., [UniProtKB, HAMAP, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0051539 4 iron, 4 sulfur cluster binding;GO:0051536 iron-sulfur cluster binding;GO:0140663 ATP-dependent FeS chaperone activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0005814 centriole;GO:0005930 axoneme", "go_biological_process": "GO:0016226 iron-sulfur cluster assembly;GO:0030030 cell projection organization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q24K00-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q24K11-1", "uniprot_id": "AP3M1_BOVIN", "mass": 46897.0, "length": 418, "protein_name": "AP-3 complex subunit mu-1", "gene_name": "AP3M1", "organism": "Bovine", "refseq_name": "AP-3 complex subunit mu-1", "refseq_ac": "NP_001069148", "gene_names_uniprotkb": "AP3M1", "gene_names_refseq": "AP3M1", "protein_names_uniprotkb": "AP-3 complex subunit mu-1; AP-3 adaptor complex mu3A subunit; Adaptor-related protein complex 3 subunit mu-1; Mu-adaptin 3A; Mu3A-adaptin", "protein_names_refseq": "AP-3 adapter complex mu3A subunit; AP-3 adaptor complex mu3A subunit; AP-3 complex subunit mu-1; adapter-related protein complex 3 mu-1 subunit; adapter-related protein complex 3 subunit mu-1; adaptor related protein complex 3 mu 1 subunit; mu-adaptin 3A; mu3A-adaptin", "tax_id": 9913, "disease": "", "pathway": " (bta:514761)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0035615 clathrin adaptor activity", "go_cellular_component": "GO:0005802 trans-Golgi network;GO:1904115 axon cytoplasm;GO:0030121 AP-1 adaptor complex", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0006897 endocytosis;GO:0008089 anterograde axonal transport;GO:0048490 anterograde synaptic vesicle transport;GO:0006896 Golgi to vacuole transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q24K11-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q24K15-1", "uniprot_id": "ANGP4_BOVIN", "mass": 55929.0, "length": 498, "protein_name": "Angiopoietin-4", "gene_name": "ANGPT4", "organism": "Bovine", "refseq_name": "angiopoietin-4 precursor", "refseq_ac": "NP_001069951", "gene_names_uniprotkb": "ANGPT4", "gene_names_refseq": "ANGPT4; ANGPTL4", "protein_names_uniprotkb": "Angiopoietin-4; ANG-4", "protein_names_refseq": "ANG-4; angiopoietin-4 precursor; angiopoietin-like protein 4", "tax_id": 9913, "disease": "", "pathway": " (bta:617915)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Binds to TEK/TIE2, modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK/TIE2. Promotes endothelial cell survival, migration and angiogenesis (By similarity)., [UniProtKB]", "predicted_glycosites": 8, "predicted_n_glycosites": 8, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 8, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0030971 receptor tyrosine kinase binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0031012 extracellular matrix", "go_biological_process": "GO:0001525 angiogenesis;GO:0007165 signal transduction;GO:0007596 blood coagulation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q24K15-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q24K22-1", "uniprot_id": "HGFL_BOVIN", "mass": 79973.0, "length": 712, "protein_name": "Hepatocyte growth factor-like protein", "gene_name": "MST1", "organism": "Bovine", "refseq_name": "hepatocyte growth factor-like protein precursor", "refseq_ac": "NP_001069145", "gene_names_uniprotkb": "MST1; HGFL", "gene_names_refseq": "MST1", "protein_names_uniprotkb": "Hepatocyte growth factor-like protein; MSP; Macrophage stimulatory protein; Macrophage-stimulating protein", "protein_names_refseq": "MSP; hepatocyte growth factor-like protein precursor; hepatocyte growth factor-like protein; macrophage stimulating 1 (hepatocyte growth factor-like); macrophage stimulatory protein; macrophage-stimulating protein", "tax_id": 9913, "disease": "", "pathway": " (bta:514667)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 4, "predicted_n_glycosites": 3, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0030971 receptor tyrosine kinase binding", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0046425 regulation of receptor signaling pathway via JAK-STAT;GO:0006508 proteolysis;GO:0045721 negative regulation of gluconeogenesis;GO:2000479 regulation of cAMP-dependent protein kinase activity", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q24K22-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q27967-1", "uniprot_id": "SPP24_BOVIN", "mass": 23134.0, "length": 203, "protein_name": "Secreted phosphoprotein 24", "gene_name": "SPP2", "organism": "Bovine", "refseq_name": "secreted phosphoprotein 24 precursor", "refseq_ac": "NP_776613", "gene_names_uniprotkb": "SPP2; SPP24", "gene_names_refseq": "SPP2; spp24", "protein_names_uniprotkb": "Secreted phosphoprotein 24; Secreted phosphoprotein 2; Spp-24", "protein_names_refseq": "secreted phosphoprotein 2, 24kDa; secreted phosphoprotein 24 precursor; secreted phosphoprotein 24; spp-24", "tax_id": 9913, "disease": "", "pathway": " (bta:281500); (R-BTA-114608); (R-BTA-381426); (R-BTA-8957275)", "pathway_count": 4, "publication_count": 4, "publication_id_list": "18075815;20615094;22949401;7814406", "class_list": "", "function": "Could coordinate an aspect of bone turnover., [UniProtKB]; Levels of spp24 in bone may be regulated, in part, by calcium-dependent proteolysis mediated by osteoblastic cells, [RefSeq, PubMed]; The beta-pleated sheets of recombinant spp24 play a greater role in bone morphogenetic protein (BMP)-2 binding than does the alpha-helical turn., [RefSeq, PubMed]; We report here for the first time the direct isolation of Spp24 covalently bound to alpha2-macroglobulins as a core complex (Spp24-alpha2M) from bovine calf serum., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q3ZBZ5", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "GO:0046849 bone remodeling", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q27967-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q27969-1", "uniprot_id": "ITFG2_BOVIN", "mass": 58160.0, "length": 532, "protein_name": "KICSTOR complex protein ITFG2", "gene_name": "ITFG2", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "ITFG2; ADP50", "gene_names_refseq": "", "protein_names_uniprotkb": "KICSTOR complex protein ITFG2; Adrenal medulla 50 kDa protein; Integrin-alpha FG-GAP repeat-containing protein 2", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (bta:282275)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "As part of the KICSTOR complex functions in the amino acid-sensing branch of the TORC1 signaling pathway. Recruits, in an amino acid-independent manner, the GATOR1 complex to the lysosomal membranes and allows its interaction with GATOR2 and the RAG GTPases. Functions upstream of the RAG GTPases and is required to negatively regulate mTORC1 signaling in absence of amino acids. In absence of the KICSTOR complex mTORC1 is constitutively localized to the lysosome and activated. The KICSTOR complex is also probably involved in the regulation of mTORC1 by glucose., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0140007 KICSTOR complex;GO:0005765 lysosomal membrane", "go_biological_process": "GO:0042149 cellular response to glucose starvation;GO:0032006 regulation of TOR signaling;GO:0034198 cellular response to amino acid starvation;GO:1904262 negative regulation of TORC1 signaling", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q27969-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q28009-1", "uniprot_id": "FUS_BOVIN", "mass": 52311.0, "length": 513, "protein_name": "RNA-binding protein FUS", "gene_name": "FUS", "organism": "Bovine", "refseq_name": "RNA-binding protein FUS", "refseq_ac": "NP_776337", "gene_names_uniprotkb": "FUS", "gene_names_refseq": "FUS", "protein_names_uniprotkb": "RNA-binding protein FUS; Protein pigpen", "protein_names_refseq": "16) in malignant liposarcoma); 16) malignant liposarcoma; RNA-binding protein FUS; fused in sarcoma; fusion (involved in t(12; fusion, derived from t(12; protein pigpen", "tax_id": 9913, "disease": "", "pathway": " (bta:280796)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "10694442;8631501", "class_list": "", "function": "DNA/RNA-binding protein that plays a role in various cellular processes such as transcription regulation, RNA splicing, RNA transport, DNA repair and damage response. Binds to ssRNA containing the consensus sequence 5'-AGGUAA-3' (By similarity). Binds to nascent pre-mRNAs and acts as a molecular mediator between RNA polymerase II and U1 small nuclear ribonucleoprotein thereby coupling transcription and splicing. Also binds its own pre-mRNA and autoregulates its expression; this autoregulation mechanism is mediated by non-sense-mediated decay. Plays a role in DNA repair mechanisms by promoting D-loop formation and homologous recombination during DNA double-strand break repair (By similarity). In neuronal cells, plays crucial roles in dendritic spine formation and stability, RNA transport, mRNA stability and synaptic homeostasis (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q0P5J2", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0003723 RNA binding;GO:0008270 zinc ion binding;GO:0003712 transcription coregulator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006355 regulation of DNA-templated transcription;GO:0008380 RNA splicing", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q28009-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q28013-1", "uniprot_id": "RASA3_BOVIN", "mass": 95386.0, "length": 834, "protein_name": "Ras GTPase-activating protein 3", "gene_name": "RASA3", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "RASA3", "gene_names_refseq": "", "protein_names_uniprotkb": "Ras GTPase-activating protein 3; GAP1(IP4BP); Ins P4-binding protein", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "8530488", "class_list": "", "function": "Inhibitory regulator of the Ras-cyclic AMP pathway. May bind inositol tetrakisphosphate (IP4)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005096 GTPase activator activity;GO:0008270 zinc ion binding", "go_cellular_component": "", "go_biological_process": "GO:0046580 negative regulation of Ras protein signal transduction;GO:0035556 intracellular signal transduction;GO:0006950 response to stress;GO:1902531 regulation of intracellular signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q28013-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q28065-1", "uniprot_id": "C4BPA_BOVIN", "mass": 68886.0, "length": 610, "protein_name": "C4b-binding protein alpha chain", "gene_name": "C4BPA", "organism": "Bovine", "refseq_name": "C4b-binding protein alpha chain", "refseq_ac": "NP_776677", "gene_names_uniprotkb": "C4BPA", "gene_names_refseq": "C4BPA", "protein_names_uniprotkb": "C4b-binding protein alpha chain; C4bp", "protein_names_refseq": "C4b-binding protein alpha chain; C4bp; complement component 4 binding protein, alpha chain", "tax_id": 9913, "disease": "", "pathway": " (bta:281651)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "7930621", "class_list": "", "function": "Controls the classical pathway of complement activation. It binds as a cofactor to C3b/C4b inactivator (C3bINA), which then hydrolyzes the complement fragment C4b. It also accelerates the degradation of the C4bC2a complex (C3 convertase) by dissociating the complement fragment C2a. Alpha chain binds C4b. It also interacts with serum amyloid P component., [UniProtKB]", "predicted_glycosites": 4, "predicted_n_glycosites": 4, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "Q2KJ87", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005615 extracellular space;GO:0005886 plasma membrane", "go_biological_process": "GO:0045087 innate immune response;GO:0045959 negative regulation of complement activation, classical pathway;GO:0002456 T cell mediated immunity;GO:0006958 complement activation, classical pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q28065-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q28066-1", "uniprot_id": "C4BPB_BOVIN", "mass": 22829.0, "length": 198, "protein_name": "C4b-binding protein beta chain", "gene_name": "C4BPB", "organism": "Bovine", "refseq_name": "C4b-binding protein beta chain precursor", "refseq_ac": "NP_776678", "gene_names_uniprotkb": "C4BPB", "gene_names_refseq": "C4BPB", "protein_names_uniprotkb": "C4b-binding protein beta chain", "protein_names_refseq": "C4b-binding protein beta chain precursor; C4b-binding protein beta chain", "tax_id": 9913, "disease": "", "pathway": " (bta:281652)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "7930621", "class_list": "", "function": "Controls the classical pathway of complement activation. It binds as a cofactor to C3b/C4b inactivator (C3bINA), which then hydrolyzes the complement fragment C4b. It also accelerates the degradation of the C4bC2a complex (C3 convertase) by dissociating the complement fragment C2a. It also interacts with serum amyloid P component., [UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "Q2KIR2", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "GO:0045087 innate immune response;GO:0006958 complement activation, classical pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q28066-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q28068-1", "uniprot_id": "CALI_BOVIN", "mass": 66890.0, "length": 588, "protein_name": "Calicin", "gene_name": "CCIN", "organism": "Bovine", "refseq_name": "calicin", "refseq_ac": "NP_776430", "gene_names_uniprotkb": "CCIN", "gene_names_refseq": "CCIN", "protein_names_uniprotkb": "Calicin", "protein_names_refseq": "calicin", "tax_id": 9913, "disease": "", "pathway": " (bta:281041)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "7641791", "class_list": "", "function": "Required for both nuclear and acrosomal shaping during spermiogenesis., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q2T9L7", "ec_number_list": "", "go_molecular_function": "GO:1990756 ubiquitin-like ligase-substrate adaptor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005856 cytoskeleton;GO:0033150 cytoskeletal calyx;GO:0031463 Cul3-RING ubiquitin ligase complex;GO:0120238 sperm glycocalyx", "go_biological_process": "GO:0007283 spermatogenesis;GO:0030154 cell differentiation;GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q28068-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q28073-1", "uniprot_id": "CD3E_BOVIN", "mass": 21523.0, "length": 192, "protein_name": "T-cell surface glycoprotein CD3 epsilon chain", "gene_name": "CD3E", "organism": "Bovine", "refseq_name": "T-cell surface glycoprotein CD3 epsilon chain precursor", "refseq_ac": "NP_776436", "gene_names_uniprotkb": "CD3E", "gene_names_refseq": "CD3E", "protein_names_uniprotkb": "T-cell surface glycoprotein CD3 epsilon chain", "protein_names_refseq": "CD3e molecule, epsilon (CD3-TCR complex); T-cell surface glycoprotein CD3 epsilon chain precursor; T-cell surface glycoprotein CD3 epsilon chain; antigen CD3E, epsilon polypeptide (TiT3 complex)", "tax_id": 9913, "disease": "", "pathway": " (bta:281054); (R-BTA-198933); (R-BTA-202424); (R-BTA-202427); (R-BTA-202430); (R-BTA-202433); (R-BTA-389948)", "pathway_count": 7, "publication_count": 1, "publication_id_list": "1971793", "class_list": "", "function": "Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD247/CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of downstream signaling pathways. CD3E ITAM phosphorylation creates docking sites for the protein kinase ZAP70 leading to ZAP70 phosphorylation and its conversion into a catalytically active enzyme. In addition of this role of signal transduction in T-cell activation, CD3E plays an essential role in correct T-cell development (By similarity). Also participates in internalization and cell surface down-regulation of TCR-CD3 complexes via endocytosis sequences present in CD3E cytosolic region (By similarity). In addition to its role as a TCR coreceptor, it serves as a receptor for ITPRIPL1 (By similarity). Ligand recognition inhibits T-cell activation by promoting interaction with NCK1, which prevents CD3E-ZAP70 interaction and blocks the ERK-NFkB signaling cascade and calcium influx (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q3ZCH2", "ec_number_list": "", "go_molecular_function": "GO:0004888 transmembrane signaling receptor activity;GO:0030674 protein-macromolecule adaptor activity", "go_cellular_component": "GO:0009897 external side of plasma membrane;GO:0042105 alpha-beta T cell receptor complex", "go_biological_process": "GO:0007166 cell surface receptor signaling pathway;GO:0010628 positive regulation of gene expression;GO:0050852 T cell receptor signaling pathway;GO:0002250 adaptive immune response;GO:0009966 regulation of signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q28073-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q28085-1", "uniprot_id": "CFAH_BOVIN", "mass": 140374.0, "length": 1236, "protein_name": "Complement factor H", "gene_name": "CFH", "organism": "Bovine", "refseq_name": "complement factor H precursor", "refseq_ac": "NP_001029108", "gene_names_uniprotkb": "CFH; HF1", "gene_names_refseq": "CFH; HF1", "protein_names_uniprotkb": "Complement factor H; H factor 1", "protein_names_refseq": "H factor 1 (complement); complement factor H precursor", "tax_id": 9913, "disease": "", "pathway": " (bta:280816)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "8615824", "class_list": "", "function": "Glycoprotein that plays an essential role in maintaining a well-balanced immune response by modulating complement activation. Acts as a soluble inhibitor of complement, where its binding to self markers such as glycan structures prevents complement activation and amplification on cell surfaces. Accelerates the decay of the complement alternative pathway (AP) C3 convertase C3bBb, thus preventing local formation of more C3b, the central player of the complement amplification loop. As a cofactor of the serine protease factor I, CFH also regulates proteolytic degradation of already-deposited C3b. In addition, mediates several cellular responses through interaction with specific receptors. For example, interacts with CR3/ITGAM receptor and thereby mediates the adhesion of human neutrophils to different pathogens. In turn, these pathogens are phagocytosed and destroyed., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "Q3MHF3;Q9TQZ7", "ec_number_list": "", "go_molecular_function": "GO:0001851 complement component C3b binding", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0006956 complement activation;GO:0006957 complement activation, alternative pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q28085-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q28088-1", "uniprot_id": "CRGC_BOVIN", "mass": 20874.0, "length": 174, "protein_name": "Gamma-crystallin C", "gene_name": "CRYGC", "organism": "Bovine", "refseq_name": "gamma-crystallin C", "refseq_ac": "NP_001013613", "gene_names_uniprotkb": "CRYGC", "gene_names_refseq": "CRYGC", "protein_names_uniprotkb": "Gamma-crystallin C; Gamma-C-crystallin; Gamma-crystallin IIIA", "protein_names_refseq": "gamma-C-crystallin; gamma-crystallin C; gamma-crystallin IIIA; gammaC-crystallin", "tax_id": 9913, "disease": "", "pathway": " (bta:281722)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "18509547;7925695", "class_list": "", "function": "Crystallins are the dominant structural components of the vertebrate eye lens., [UniProtKB]; The results are consistent with the hypothesis that short-range, weak, attractive interactions between alpha- and gamma-crystallins are necessary for maximum transparency of the lens. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A3RLE3", "ec_number_list": "", "go_molecular_function": "GO:0005212 structural constituent of eye lens", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0007601 visual perception;GO:0002088 lens development in camera-type eye", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q28088-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q28092-1", "uniprot_id": "CYLC2_BOVIN", "mass": 53562.0, "length": 488, "protein_name": "Cylicin-2", "gene_name": "CYLC2", "organism": "Bovine", "refseq_name": "cylicin-2", "refseq_ac": "NP_776728", "gene_names_uniprotkb": "CYLC2; CYL2", "gene_names_refseq": "CYLC2", "protein_names_uniprotkb": "Cylicin-2; Cylicin II; Multiple-band polypeptide II", "protein_names_refseq": "cylicin II; cylicin, basic protein of sperm head cytoskeleton 2; cylicin-2; multiple-band polypeptide II", "tax_id": 9913, "disease": "", "pathway": " (bta:281738)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "7737358;8354692", "class_list": "", "function": "Plays a role in the establishment of normal sperm morphology during spermatogenesis. It is required for acrosome attachment to the nuclear envelope, and proper manchette elongation and disassembly., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005200 structural constituent of cytoskeleton", "go_cellular_component": "GO:0033150 cytoskeletal calyx", "go_biological_process": "GO:0007283 spermatogenesis;GO:0030154 cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q28092-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q28105-1", "uniprot_id": "EPCR_BOVIN", "mass": 27010.0, "length": 241, "protein_name": "Endothelial protein C receptor", "gene_name": "PROCR", "organism": "Bovine", "refseq_name": "endothelial protein C receptor precursor", "refseq_ac": "NP_776862", "gene_names_uniprotkb": "PROCR; EPCR", "gene_names_refseq": "EPCR; PROCR", "protein_names_uniprotkb": "Endothelial protein C receptor; APC receptor; Activated protein C receptor; Endothelial cell protein C receptor", "protein_names_refseq": "APC receptor; activated protein C receptor; endothelial cell protein C receptor; endothelial cell protein C/activated protein C; endothelial protein C receptor precursor; endothelial protein C receptor", "tax_id": 9913, "disease": "", "pathway": " (bta:282005); (R-BTA-202733); (R-BTA-9769739)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "7890676", "class_list": "", "function": "Binds activated protein C. Enhances protein C activation by the thrombin-thrombomodulin complex; plays a role in the protein C pathway controlling blood coagulation., [UniProtKB]", "predicted_glycosites": 4, "predicted_n_glycosites": 4, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "Q1LZD2", "ec_number_list": "", "go_molecular_function": "GO:0038023 signaling receptor activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0016020 membrane", "go_biological_process": "GO:0007596 blood coagulation;GO:0050819 negative regulation of coagulation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q28105-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q28120-1", "uniprot_id": "QPCT_BOVIN", "mass": 41224.0, "length": 361, "protein_name": "Glutaminyl-peptide cyclotransferase", "gene_name": "QPCT", "organism": "Bovine", "refseq_name": "glutaminyl-peptide cyclotransferase precursor", "refseq_ac": "NP_803472", "gene_names_uniprotkb": "QPCT", "gene_names_refseq": "QPCT", "protein_names_uniprotkb": "Glutaminyl-peptide cyclotransferase; 2.3.2.5; Glutaminyl cyclase; Glutaminyl-tRNA cyclotransferase; QC", "protein_names_refseq": "QC; glutaminyl cyclase; glutaminyl-peptide cyclotransferase precursor; glutaminyl-tRNA cyclotransferase", "tax_id": 9913, "disease": "", "pathway": " (bta:281437)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "1946423", "class_list": "", "function": "Responsible for the biosynthesis of pyroglutamyl peptides. Has a bias against acidic and tryptophan residues adjacent to the N-terminal glutaminyl residue and a lack of importance of chain length after the second residue. Also catalyzes N-terminal pyroglutamate formation (By similarity)., [UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.3.2.5", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0016603 glutaminyl-peptide cyclotransferase activity", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q28120-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q28125-1", "uniprot_id": "ICAM3_BOVIN", "mass": 59735.0, "length": 544, "protein_name": "Intercellular adhesion molecule 3", "gene_name": "ICAM3", "organism": "Bovine", "refseq_name": "intercellular adhesion molecule 3 precursor", "refseq_ac": "NP_776774", "gene_names_uniprotkb": "ICAM3", "gene_names_refseq": "ICAM3", "protein_names_uniprotkb": "Intercellular adhesion molecule 3; ICAM-3", "protein_names_refseq": "ICAM-3; intercellular adhesion molecule 3 precursor", "tax_id": 9913, "disease": "", "pathway": " (bta:281840)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "8890753", "class_list": "", "function": "Cell adhesion molecule that functions as a receptor ligand of the signaling receptor ITGAL:ITGB2/LFA-1 (lymphocyte-function associated (LFA) molecule 1) ensuring apoptotic neutrophil phagocytosis by macrophages. Is also a ligand for integrin ITGAD/ITGB2. Ligand of CD209 on dendritic cells (DC) through an integrin-independent mechanism that requires Ca(2+) and that forms a first contact between DC and resting T cell, facilitating the downstream DC-T cell clustering process and DC-induced proliferation of resting T Cells., [UniProtKB, UniProtKB]", "predicted_glycosites": 15, "predicted_n_glycosites": 15, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 15, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005178 integrin binding", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0006955 immune response;GO:0007155 cell adhesion;GO:0006909 phagocytosis;GO:0007159 leukocyte cell-cell adhesion;GO:0050900 leukocyte migration", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q28125-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q28145-1", "uniprot_id": "NXPH2_BOVIN", "mass": 29977.0, "length": 264, "protein_name": "Neurexophilin-2", "gene_name": "NXPH2", "organism": "Bovine", "refseq_name": "neurexophilin-2 precursor", "refseq_ac": "NP_776831", "gene_names_uniprotkb": "NXPH2; NPH2", "gene_names_refseq": "NXPH2", "protein_names_uniprotkb": "Neurexophilin-2; Neurophilin-2", "protein_names_refseq": "neurexophilin-2 precursor; neurophilin-2", "tax_id": 9913, "disease": "", "pathway": " (bta:281956)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "8420960;8699246", "class_list": "", "function": "May be signaling molecules that resemble neuropeptides and that act by binding to alpha-neurexins and possibly other receptors., [UniProtKB]", "predicted_glycosites": 4, "predicted_n_glycosites": 4, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005102 signaling receptor binding", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q28145-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q28151-1", "uniprot_id": "OZF_BOVIN", "mass": 33269.0, "length": 292, "protein_name": "Zinc finger protein OZF", "gene_name": "ZNF146", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "ZNF146; OZF", "gene_names_refseq": "", "protein_names_uniprotkb": "Zinc finger protein OZF; Only zinc finger protein; Zinc finger protein 146", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "8561900", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0031981 nuclear lumen;GO:0005634 nucleus;GO:0005829 cytosol", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q28151-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q28161-1", "uniprot_id": "PKP1_BOVIN", "mass": 80180.0, "length": 727, "protein_name": "Plakophilin-1", "gene_name": "PKP1", "organism": "Bovine", "refseq_name": "plakophilin-1", "refseq_ac": "NP_776570", "gene_names_uniprotkb": "PKP1", "gene_names_refseq": "PKP1", "protein_names_uniprotkb": "Plakophilin-1; B6P; Band-6 protein", "protein_names_refseq": "B6P; armadillo; band 6; band-6 protein; plakophilin 1 (ectodermal dysplasia/skin fragility syndrome); plakophilin-1", "tax_id": 9913, "disease": "", "pathway": " (bta:281405)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "7890138", "class_list": "", "function": "A component of desmosome cell-cell junctions which are required for positive regulation of cellular adhesion (By similarity). Plays a role in desmosome protein expression regulation and localization to the desmosomal plaque, thereby maintaining cell sheet integrity and anchorage of desmosomes to intermediate filaments (By similarity). Required for localization of DSG3 and YAP1 to the cell membrane in keratinocytes in response to mechanical strain, via the formation of an interaction complex composed of DSG3, YAP1, PKP1 and YWHAG (By similarity). Positively regulates differentiation of keratinocytes, potentially via promoting localization of DSG1 at desmosome cell junctions (By similarity). Required for calcium-independent development and maturation of desmosome plaques specifically at lateral cell-cell contacts in differentiating keratinocytes (By similarity). Plays a role in the maintenance of DSG3 protein abundance, DSG3 clustering and localization of these clusters to the cell membrane in keratinocytes (By similarity). May also promote keratinocyte proliferation and morphogenesis during postnatal development (By similarity). Required for tight junction inside-out transepidermal barrier function of the skin (By similarity). Promotes Wnt-mediated proliferation and differentiation of ameloblasts, via facilitating TJP1/ZO-1 localization to tight junctions (By similarity). Binds single-stranded DNA (ssDNA), and may thereby play a role in sensing DNA damage and promoting cell survival (By similarity). Positively regulates cap-dependent translation and as a result cell proliferation, via recruitment of EIF4A1 to the initiation complex and promotion of EIF4A1 ATPase activity (By similarity). Regulates the mRNA stability and protein abundance of desmosome components PKP2, PKP3, DSC2 and DSP, potentially via its interaction with FXR1 (By similarity). May facilitate the formation of intermediate filaments (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0003723 RNA binding;GO:0045296 cadherin binding", "go_cellular_component": "GO:0097165 nuclear stress granule;GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0005912 adherens junction", "go_biological_process": "GO:0022409 positive regulation of cell-cell adhesion;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0098609 cell-cell adhesion;GO:1903078 positive regulation of protein localization to plasma membrane;GO:0002159 desmosome assembly", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q28161-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q28201-1", "uniprot_id": "TKDP1_BOVIN", "mass": 38255.0, "length": 351, "protein_name": "Trophoblast Kunitz domain protein 1", "gene_name": "TKDP1", "organism": "Bovine", "refseq_name": "trophoblast Kunitz domain protein 1 precursor", "refseq_ac": "NP_991345", "gene_names_uniprotkb": "TKDP1", "gene_names_refseq": "TKDP1", "protein_names_uniprotkb": "Trophoblast Kunitz domain protein 1; TKDP-1", "protein_names_refseq": "Kunitz-type proteinase inhibitor; TKDP-1; trophoblast Kunitz domain protein 1 precursor; trypsin inhibitor", "tax_id": 9913, "disease": "", "pathway": " (bta:404076)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "7510284", "class_list": "", "function": "May play a role in mediating maternal-conceptus interactions in the immediate preimplantation period. Does not seem to have proteinase inhibitory activity (By similarity)., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q9N0X8", "ec_number_list": "", "go_molecular_function": "GO:0004867 serine-type endopeptidase inhibitor activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q28201-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q28880-1", "uniprot_id": "LAP_BOVIN", "mass": 7041.0, "length": 64, "protein_name": "Lingual antimicrobial peptide", "gene_name": "LAP", "organism": "Bovine", "refseq_name": "lingual antimicrobial peptide precursor", "refseq_ac": "NP_982259", "gene_names_uniprotkb": "LAP", "gene_names_refseq": "LAP", "protein_names_uniprotkb": "Lingual antimicrobial peptide", "protein_names_refseq": "LAP-related prepropeptide; lingual antimicrobial peptide precursor", "tax_id": 9913, "disease": "", "pathway": " (bta:403090)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "19448002;21255844;21674298;23298865;7886453;8613361", "class_list": "", "function": "LAP was detected in the eluate by competitive enzyme immunoassay and had antimicrobial activity against E. coli, [RefSeq, PubMed]; Shows a broad spectrum of antibacterial and antifungal activities., [UniProtKB, PubMed]; Stimulation of umbilical-vein endothelial cells with S. aureus or LPS induced the expression of lingual antimicrobial peptide. This expression was regulated by the autocrine production of tumor necrosis factor-alpha., [RefSeq, PubMed]; The results from this study clearly demonstrate the involvement of octamer transcription factor-1 in the regulation of tracheal antimicrobial peptide and lingual antimicrobial peptide expression., [RefSeq, PubMed]; The role of NF-kappaB and C/EBP factors in regulating basal and pathogen-induced expression of both genes from cattle, is investigated., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q28202;Q56JV8", "ec_number_list": "", "go_molecular_function": "GO:0042056 chemoattractant activity;GO:0031731 CCR6 chemokine receptor binding", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0060326 cell chemotaxis;GO:0042742 defense response to bacterium;GO:0031640 killing of cells of another organism;GO:0050832 defense response to fungus", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q28880-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q288C4-1", "uniprot_id": "NLRP9_BOVIN", "mass": 114162.0, "length": 996, "protein_name": "NACHT, LRR and PYD domains-containing protein 9", "gene_name": "NLRP9", "organism": "Bovine", "refseq_name": "NACHT, LRR and PYD domains-containing protein 9", "refseq_ac": "NP_001019835", "gene_names_uniprotkb": "NLRP9; NALP9", "gene_names_refseq": "NALP9; NLRP9", "protein_names_uniprotkb": "NACHT, LRR and PYD domains-containing protein 9", "protein_names_refseq": "NACHT, LRR and PYD domains-containing protein 9; NACHT, leucine rich repeat and PYD containing 9", "tax_id": 9913, "disease": "", "pathway": " (bta:520716)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "15892040;16339045;35090055", "class_list": "", "function": "As the sensor component of the NLRP9 inflammasome, plays a crucial role in innate immunity and inflammation. In response to pathogens, including rotavirus, initiates the formation of the inflammasome polymeric complex, made of NLRP9, PYCARD and CASP1. Recruitment of proCASP1 to the inflammasome promotes its activation and CASP1-catalyzed IL1B and IL18 maturation and release in the extracellular milieu. The active cytokines stimulate inflammatory responses. Inflammasomes can also induce pyroptosis, an inflammatory form of programmed cell death. NLRP9 inflammasome activation may be initiated by DHX9 interaction with viral double-stranded RNA (dsRNA), preferentially to short dsRNA segments., [UniProtKB, UniProtKB]; Assignment to a QTL region for reproductive traits and preferential expression of NALP9, NALP8, and NALP5 in oocyte, germinal lineage, and gonad cells may suggest their functional relevance to reproduction and possible contribution to phenotypic variation, [RefSeq, PubMed]; Novel oocyte marker gene in cattle, [RefSeq, PubMed]; The structure of NLRP9 reveals a unique C-terminal region with putative regulatory function., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q4U4S5", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0061702 canonical inflammasome complex", "go_biological_process": "GO:0006954 inflammatory response;GO:0045087 innate immune response;GO:0050727 regulation of inflammatory response", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q288C4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q28918-1", "uniprot_id": "STAR_BOVIN", "mass": 31871.0, "length": 285, "protein_name": "Steroidogenic acute regulatory protein, mitochondrial", "gene_name": "STAR", "organism": "Bovine", "refseq_name": "steroidogenic acute regulatory protein, mitochondrial precursor", "refseq_ac": "NP_776614", "gene_names_uniprotkb": "STAR", "gene_names_refseq": "STAR", "protein_names_uniprotkb": "Steroidogenic acute regulatory protein, mitochondrial; START domain-containing protein 1; StARD1; StAR", "protein_names_refseq": "START domain-containing protein 1; stARD1; steroidogenic acute regulatory protein, mitochondrial precursor; steroidogenic acute regulatory protein, mitochondrial", "tax_id": 9913, "disease": "", "pathway": " (bta:281507); (R-BTA-196108); (R-BTA-9837999)", "pathway_count": 3, "publication_count": 8, "publication_id_list": "17029976;18974265;21072679;22155568;22829687;24708239;7488004;7626524", "class_list": "", "function": "C-Fos/c-Jun complex binds to the proximal StAR promoter in glomerulosa cells, thus activating StAR gene expression and acute aldosterone biosynthesis., [RefSeq, PubMed]; Data indicate that Ser738/742-to-glutamate protein kinase D mutant increased AngII-induced CREB protein and activating transcription factor 2 phosphorylation, and phospho-CREB binding to the steroidogenic acute regulatory protein promoter., [RefSeq, PubMed]; Data suggest that Escherichia coli infections (here, administration of LPS) provokes luteolysis in diestrus, non-lactating cows and down-regulation of expression of StAR in corpus luteum but has no effect on luteinization in the following cycle., [RefSeq, PubMed]; Inhibition of the acetylation of histone H3 associated with the StAR promoter region by BMP-4 may be one of the inhibitory molecular mechanisms of progesterone synthesis in granulosa cells., [RefSeq, PubMed]; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone (By similarity)., [UniProtKB, UniProtKB]; The binding of SF-1 to the CYP17 and StAR promoter regions increased in theca cells incubated with low levels of luteinizing hormone., [RefSeq, PubMed]; These mutant StAR proteins expressed in COS-1 cells were not cleaved at positions 39-40 and 54-55, and were processed at sites different from those in the wild-type StAR protein., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q2YDI1", "ec_number_list": "", "go_molecular_function": "GO:0015485 cholesterol binding;GO:0120020 cholesterol transfer activity", "go_cellular_component": "GO:0005741 mitochondrial outer membrane;GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0008203 cholesterol metabolic process;GO:0032367 intracellular cholesterol transport;GO:0006694 steroid biosynthetic process;GO:0006704 glucocorticoid biosynthetic process;GO:0050810 regulation of steroid biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q28918-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q29397-1", "uniprot_id": "SV2A_BOVIN", "mass": 82589.0, "length": 742, "protein_name": "Synaptic vesicle glycoprotein 2A", "gene_name": "SV2A", "organism": "Bovine", "refseq_name": "synaptic vesicle glycoprotein 2A", "refseq_ac": "NP_776387", "gene_names_uniprotkb": "SV2A", "gene_names_refseq": "SV2A; SV2", "protein_names_uniprotkb": "Synaptic vesicle glycoprotein 2A; p87", "protein_names_refseq": "p87; synaptic vesicle glycoprotein 2A; synaptic vesicle glycoprotein 2", "tax_id": 9913, "disease": "", "pathway": " (bta:280936)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "1426240", "class_list": "", "function": "Plays a role in the control of regulated secretion in neural and endocrine cells, enhancing selectively low-frequency neurotransmission. Positively regulates vesicle fusion by maintaining the readily releasable pool of secretory vesicles (By similarity)., [UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0019901 protein kinase binding;GO:0022857 transmembrane transporter activity", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0098982 GABA-ergic synapse;GO:0005783 endoplasmic reticulum;GO:0005911 cell-cell junction;GO:0031594 neuromuscular junction", "go_biological_process": "GO:0016082 synaptic vesicle priming", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q29397-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q29414-1", "uniprot_id": "ASIP_BOVIN", "mass": 14841.0, "length": 133, "protein_name": "Agouti-signaling protein", "gene_name": "ASIP", "organism": "Bovine", "refseq_name": "agouti-signaling protein precursor", "refseq_ac": "NP_996674", "gene_names_uniprotkb": "ASIP", "gene_names_refseq": "ASIP", "protein_names_uniprotkb": "Agouti-signaling protein; ASP; Agouti switch protein", "protein_names_refseq": "ASP; agouti signal peptide; agouti signaling protein, nonagouti homolog; agouti switch protein; agouti-signaling protein precursor", "tax_id": 9913, "disease": "", "pathway": " (bta:404192)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "15649150;16827753;22530003", "class_list": "", "function": "Our results provide evidence for a widespread expression of ASIP in bovine tissues at mRNA and, for the first time, at protein level., [RefSeq, PubMed]; Possible consequences of Abr (agouti gene mutated by insertion of LINE element)for meat and milk production in cattle., [RefSeq, PubMed]; Signaling protein that functions as an antagonist of melanocyte-stimulating-hormone receptor MC1R, thereby playing a role in the regulation of melanogenesis (By similarity). Binding to MC1R prevents alpha-MSH-induced signaling and inhibits cAMP production, resulting in down-regulation of eumelanogenesis (brown/black pigment) and increased pheomelanin (yellow/red pigment) synthesis (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 1, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "Q3T0R3;Q53Z62", "ec_number_list": "", "go_molecular_function": "GO:0048019 receptor antagonist activity;GO:0005184 neuropeptide hormone activity;GO:0070996 type 1 melanocortin receptor binding;GO:0031779 melanocortin receptor binding", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0009755 hormone-mediated signaling pathway;GO:0032438 melanosome organization;GO:0042438 melanin biosynthetic process;GO:0106072 negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q29414-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q29438-1", "uniprot_id": "ODFP1_BOVIN", "mass": 29435.0, "length": 262, "protein_name": "Outer dense fiber protein 1", "gene_name": "ODF1", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "ODF1; ODFP", "gene_names_refseq": "", "protein_names_uniprotkb": "Outer dense fiber protein 1", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "7576240", "class_list": "", "function": "Component of the outer dense fibers (ODF) of spermatozoa. ODF are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail and may help to maintain the passive elastic structures and elastic recoil of the sperm tail., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 10, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0001520 outer dense fiber;GO:0005813 centrosome;GO:0036126 sperm flagellum;GO:0002177 manchette", "go_biological_process": "GO:0007283 spermatogenesis;GO:0030154 cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q29438-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q29RH2-1", "uniprot_id": "TET5B_BOVIN", "mass": 47097.0, "length": 430, "protein_name": "Terminal nucleotidyltransferase 5B", "gene_name": "TENT5B", "organism": "Bovine", "refseq_name": "terminal nucleotidyltransferase 5B", "refseq_ac": "NP_001039415", "gene_names_uniprotkb": "TENT5B; FAM46B", "gene_names_refseq": "FAM46B; TENT5B", "protein_names_uniprotkb": "Terminal nucleotidyltransferase 5B; 2.7.7.19; Non-canonical poly(A) polymerase FAM46B", "protein_names_refseq": "family with sequence similarity 46 member B; non-canonical poly(A) polymerase FAM46B; protein FAM46B; putative nucleotidyltransferase FAM46B; terminal nucleotidyltransferase 5B", "tax_id": 9913, "disease": "", "pathway": " (bta:506745)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalyzes the transfer of one adenosine molecule from an ATP to an mRNA poly(A) tail bearing a 3'-OH terminal group in an ATP hydrolysis-dependent manner. May be involved in maintaining the translation efficiency of at least some genes through preventing degradation of their mRNAs. Prefers RNA molecules that are adenosine-rich close to 3'-end. In addition, may inhibit cell proliferation and cell cycle progression through ubiquitination of beta-catenin/CTNNB1., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.7.52;2.7.7.19", "go_molecular_function": "GO:1990817 poly(A) RNA polymerase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0008285 negative regulation of cell population proliferation;GO:0043066 negative regulation of apoptotic process;GO:0048255 mRNA stabilization;GO:0045727 positive regulation of translation;GO:0045786 negative regulation of cell cycle", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q29RH2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q29RJ1-1", "uniprot_id": "AP4A_BOVIN", "mass": 16775.0, "length": 147, "protein_name": "Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical]", "gene_name": "NUDT2", "organism": "Bovine", "refseq_name": "bis(5'-nucleosyl)-tetraphosphatase [asymmetrical]", "refseq_ac": "NP_001070570", "gene_names_uniprotkb": "NUDT2", "gene_names_refseq": "NUDT2", "protein_names_uniprotkb": "Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical]; 3.6.1.17; Ap4A hydrolase; Ap4Aase; Diadenosine 5',5'''-P1,P4-tetraphosphate asymmetrical hydrolase; Diadenosine tetraphosphatase; Nucleoside diphosphate-linked moiety X motif 2; Nudix motif 2", "protein_names_refseq": "ap4A hydrolase; ap4Aase; bis(5'-nucleosyl)-tetraphosphatase [asymmetrical]; bis(5'-nucleosyl)-tetraphosphatase; diadenosine 5',5'''-P1,P4-tetraphosphate asymmetrical hydrolase; diadenosine tetraphosphatase; nucleoside diphosphate-linked moiety X motif 2; nudix (nucleoside diphosphate linked moiety X)-type motif 2; nudix motif 2", "tax_id": 9913, "disease": "", "pathway": " (bta:768044); (R-BTA-3299685)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalyzes the asymmetric hydrolysis of diadenosine 5',5'''-P1,P4-tetraphosphate (Ap4A) to yield AMP and ATP (By similarity). Exhibits decapping activity towards FAD-capped RNAs and dpCoA-capped RNAs in vitro (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.6.1.77;3.6.1.9;3.6.1.68;3.6.1.76;3.6.1.17;3.6.1.62;3.6.1.64;3.6.1.-;3.1.4.1", "go_molecular_function": "GO:0005525 GTP binding;GO:0004081 bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity", "go_cellular_component": "", "go_biological_process": "GO:0006754 ATP biosynthetic process;GO:0006167 AMP biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q29RJ1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q29RJ2-1", "uniprot_id": "TBC24_BOVIN", "mass": 62937.0, "length": 559, "protein_name": "TBC1 domain family member 24", "gene_name": "TBC1D24", "organism": "Bovine", "refseq_name": "TBC1 domain family member 24", "refseq_ac": "NP_001039761", "gene_names_uniprotkb": "TBC1D24", "gene_names_refseq": "TBC1D24", "protein_names_uniprotkb": "TBC1 domain family member 24", "protein_names_refseq": "TBC1 domain family member 24", "tax_id": 9913, "disease": "", "pathway": " (bta:529002)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "May act as a GTPase-activating protein for Rab family protein(s) (By similarity). Involved in neuronal projection development, probably through negative modulation of ARF6 function (By similarity). Required for the maintenance of postsynaptic neuron dendritic spines in the adult by suppressing ARF6 activity (By similarity). Involved in the regulation of synaptic vesicle trafficking (By similarity). Promotes axonal outgrowth and membrane trafficking at the growth cone (By similarity). Positively regulates radial migration and morphological maturation of pyramidal neurons during cortical development by preventing ARF6 activation (By similarity). In one study, has been shown to inhibit the activity of the vacuolar-type ATPase (V-ATPase) by inducing disassembly of the V-ATPase complex (By similarity). In another study, has been shown to positively regulate V-ATPase assembly in neurons which promotes acidification of lysosomes and synaptic vesicles (By similarity). This supports neuronal autophagy and also regulates synaptic vesicle reacidification and the maintenance of the synaptic vesicle reserve pool (By similarity). Protects neuronal cells against oxidative stress (By similarity). Involved in the maintainenance of endosomal-mediated vesicle recycling and sustained exocytosis of hair cell ribbon synapses (By similarity). Facilitates formation of tubular recycling endosomes which promotes recycling of clathrin-independent endocytosis cargo proteins back to the plasma membrane (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0ABI0P1L6", "ec_number_list": "", "go_molecular_function": "GO:0005096 GTPase activator activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0030659 cytoplasmic vesicle membrane;GO:0098793 presynapse", "go_biological_process": "GO:0031175 neuron projection development;GO:0034599 cellular response to oxidative stress", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q29RJ2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q29RK8-1", "uniprot_id": "CXG2_BOVIN", "mass": 46067.0, "length": 429, "protein_name": "Gap junction gamma-2 protein", "gene_name": "GJC2", "organism": "Bovine", "refseq_name": "gap junction gamma-2 protein", "refseq_ac": "NP_001039905", "gene_names_uniprotkb": "GJC2; GJA12", "gene_names_refseq": "GJA12; GJC2", "protein_names_uniprotkb": "Gap junction gamma-2 protein; Gap junction alpha-12 protein", "protein_names_refseq": "gap junction alpha-12 protein; gap junction gamma-2 protein; gap junction protein, alpha 12, 47kDa; gap junction protein, gamma 2, 47kDa", "tax_id": 9913, "disease": "", "pathway": " (bta:538745); (R-BTA-190861)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "19883592", "class_list": "", "function": "AQP-0 and connexins can be segregated in the membrane by protein-lipid interactions as modified by AQP-0 homo-oligomerization, [RefSeq, PubMed]; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a role in myelination in central and peripheral nervous systems (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:1903763 gap junction channel activity involved in cell communication by electrical coupling;GO:0005243 gap junction channel activity", "go_cellular_component": "GO:0043209 myelin sheath;GO:0005922 connexin complex", "go_biological_process": "GO:0007267 cell-cell signaling", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q29RK8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q29RL1-1", "uniprot_id": "CF206_BOVIN", "mass": 71079.0, "length": 622, "protein_name": "Cilia- and flagella-associated protein 206", "gene_name": "CFAP206", "organism": "Bovine", "refseq_name": "cilia- and flagella-associated protein 206", "refseq_ac": "NP_001039602", "gene_names_uniprotkb": "CFAP206", "gene_names_refseq": "C9H6orf165; CFAP206", "protein_names_uniprotkb": "Cilia- and flagella-associated protein 206", "protein_names_refseq": "UPF0704 protein C6orf165 homolog; cilia- and flagella-associated protein 206", "tax_id": 9913, "disease": "", "pathway": " (bta:513096)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Essential for sperm motility and is involved in the regulation of the beating frequency of motile cilia on the epithelial cells of the respiratory tract (By similarity). Required for the establishment of radial spokes in sperm flagella (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0001534 radial spoke;GO:0031514 motile cilium;GO:0005930 axoneme;GO:0036064 ciliary basal body", "go_biological_process": "GO:0003341 cilium movement;GO:0003356 regulation of cilium beat frequency;GO:0035082 axoneme assembly;GO:0007288 sperm axoneme assembly;GO:1901317 regulation of flagellated sperm motility", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q29RL1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q29RM4-1", "uniprot_id": "ARGAL_BOVIN", "mass": 135085.0, "length": 1237, "protein_name": "Rho guanine nucleotide exchange factor 10-like protein", "gene_name": "ARHGEF10L", "organism": "Bovine", "refseq_name": "rho guanine nucleotide exchange factor 10-like protein", "refseq_ac": "NP_001039762", "gene_names_uniprotkb": "ARHGEF10L; GRINCHGEF", "gene_names_refseq": "ARHGEF10L", "protein_names_uniprotkb": "Rho guanine nucleotide exchange factor 10-like protein; GrinchGEF", "protein_names_refseq": "Rho guanine nucleotide exchange factor (GEF) 10-like; grinchGEF; rho guanine nucleotide exchange factor 10-like protein", "tax_id": 9913, "disease": "", "pathway": " (bta:529043)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Acts as a guanine nucleotide exchange factor (GEF) for RHOA, RHOB and RHOC., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005085 guanyl-nucleotide exchange factor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0051056 regulation of small GTPase mediated signal transduction;GO:0030036 actin cytoskeleton organization;GO:0051496 positive regulation of stress fiber assembly;GO:0032933 SREBP signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q29RM4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q29RN6-1", "uniprot_id": "SOCS5_BOVIN", "mass": 61172.0, "length": 536, "protein_name": "Suppressor of cytokine signaling 5", "gene_name": "SOCS5", "organism": "Bovine", "refseq_name": "suppressor of cytokine signaling 5", "refseq_ac": "NP_001039647", "gene_names_uniprotkb": "SOCS5", "gene_names_refseq": "SOCS5", "protein_names_uniprotkb": "Suppressor of cytokine signaling 5; SOCS-5", "protein_names_refseq": "SOCS-5; suppressor of cytokine signaling 5", "tax_id": 9913, "disease": "", "pathway": " (bta:514773)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. May be a substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Inhibits for instance EGF signaling by mediating the degradation of the EGF receptor/EGFR. Involved in the regulation of T-helper cell differentiation by inhibiting of the IL4 signaling pathway which promotes differentiation into the Th2 phenotype. Can also partially inhibit IL6 and LIF signaling (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "", "go_biological_process": "GO:0035556 intracellular signal transduction;GO:0007173 epidermal growth factor receptor signaling pathway;GO:0016567 protein ubiquitination;GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0019221 cytokine-mediated signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q29RN6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q29RP9-1", "uniprot_id": "GATA_BOVIN", "mass": 57300.0, "length": 526, "protein_name": "Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial", "gene_name": "QRSL1", "organism": "Bovine", "refseq_name": "glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial", "refseq_ac": "NP_001039801", "gene_names_uniprotkb": "QRSL1", "gene_names_refseq": "QRSL1", "protein_names_uniprotkb": "Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial; 6.3.5.7; Glu-AdT subunit A; Glutaminyl-tRNA synthase-like protein 1", "protein_names_refseq": "QRSL1, glutaminyl-tRNA amidotransferase subunit A; glu-AdT subunit A; glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1; glutaminyl-tRNA synthase-like protein 1; glutamyl-tRNA(Gln) amidotransferase subunit A homolog; glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial", "tax_id": 9913, "disease": "", "pathway": " (bta:532822)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "6.3.5.7;6.3.5.-", "go_molecular_function": "GO:0005524 ATP binding;GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex", "go_biological_process": "GO:0032543 mitochondrial translation;GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q29RP9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q29RQ1-1", "uniprot_id": "CO7_BOVIN", "mass": 93090.0, "length": 843, "protein_name": "Complement component C7", "gene_name": "C7", "organism": "Bovine", "refseq_name": "complement component C7 precursor", "refseq_ac": "NP_001039431", "gene_names_uniprotkb": "C7", "gene_names_refseq": "C7", "protein_names_uniprotkb": "Complement component C7", "protein_names_refseq": "complement component 7; complement component C7 precursor; complement component C7", "tax_id": 9913, "disease": "", "pathway": " (bta:507339)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of the membrane attack complex (MAC), a multiprotein complex activated by the complement cascade, which inserts into a target cell membrane and forms a pore, leading to target cell membrane rupture and cell lysis. The MAC is initiated by proteolytic cleavage of C5 into complement C5b in response to the classical, alternative, lectin and GZMK complement pathways. The complement pathways consist in a cascade of proteins that leads to phagocytosis and breakdown of pathogens and signaling that strengthens the adaptive immune system. C7 serves as a membrane anchor. During MAC assembly, associates with C5b and C6 to form the C5b-7 complex, a key lipophilic precursor of the MAC complex, which associates with the outer leaflet and reduces the energy for membrane bending., [UniProtKB, UniProtKB]", "predicted_glycosites": 7, "predicted_n_glycosites": 2, "predicted_o_glycosites": 1, "predicted_c_glycosites": 4, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 7, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005615 extracellular space;GO:0005579 membrane attack complex;GO:0044218 other organism cell membrane", "go_biological_process": "GO:0031640 killing of cells of another organism;GO:0006958 complement activation, classical pathway;GO:0006956 complement activation;GO:0006957 complement activation, alternative pathway;GO:0160257 complement activation, GZMK pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q29RQ1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q29RR5-1", "uniprot_id": "TFP11_BOVIN", "mass": 96085.0, "length": 837, "protein_name": "Tuftelin-interacting protein 11", "gene_name": "TFIP11", "organism": "Bovine", "refseq_name": "tuftelin-interacting protein 11", "refseq_ac": "NP_001039495", "gene_names_uniprotkb": "TFIP11; STIP", "gene_names_refseq": "STIP; TFIP11", "protein_names_uniprotkb": "Tuftelin-interacting protein 11; STIP-1; Septin and tuftelin-interacting protein 1", "protein_names_refseq": "STIP-1; septin and tuftelin-interacting protein 1; tuftelin-interacting protein 11", "tax_id": 9913, "disease": "", "pathway": " (bta:509349)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "17289020", "class_list": "", "function": "Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events. Intron turnover seems to proceed through reactions in two lariat-intron associated complexes termed Intron Large (IL) and Intron Small (IS). In cooperation with DHX15 seems to mediate the transition of the U2, U5 and U6 snRNP-containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns. May play a role in the differentiation of ameloblasts and odontoblasts or in the forming of the enamel extracellular matrix (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A1XD96", "ec_number_list": "", "go_molecular_function": "GO:0003676 nucleic acid binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005681 spliceosomal complex;GO:0071008 U2-type post-mRNA release spliceosomal complex", "go_biological_process": "GO:0031214 biomineral tissue development;GO:0000390 spliceosomal complex disassembly", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q29RR5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q29RR6-1", "uniprot_id": "VSIG1_BOVIN", "mass": 41657.0, "length": 382, "protein_name": "V-set and immunoglobulin domain-containing protein 1", "gene_name": "VSIG1", "organism": "Bovine", "refseq_name": "V-set and immunoglobulin domain-containing protein 1 precursor", "refseq_ac": "NP_001039395", "gene_names_uniprotkb": "VSIG1", "gene_names_refseq": "VSIG1", "protein_names_uniprotkb": "V-set and immunoglobulin domain-containing protein 1", "protein_names_refseq": "V-set and immunoglobulin domain-containing protein 1 precursor; V-set and immunoglobulin domain-containing protein 1", "tax_id": 9913, "disease": "", "pathway": " (bta:505937)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 4, "predicted_n_glycosites": 3, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0016323 basolateral plasma membrane", "go_biological_process": "GO:0030277 maintenance of gastrointestinal epithelium;GO:0003382 epithelial cell morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q29RR6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q29RS5-1", "uniprot_id": "RARR2_BOVIN", "mass": 18357.0, "length": 162, "protein_name": "Retinoic acid receptor responder protein 2", "gene_name": "RARRES2", "organism": "Bovine", "refseq_name": "retinoic acid receptor responder protein 2 precursor", "refseq_ac": "NP_001039485", "gene_names_uniprotkb": "RARRES2", "gene_names_refseq": "RARRES2; TIG2", "protein_names_uniprotkb": "Retinoic acid receptor responder protein 2; Chemerin", "protein_names_refseq": "chemerin; retinoic acid receptor responder (tazarotene induced) 2; retinoic acid receptor responder protein 2 precursor; retinoic acid receptor responder protein 2", "tax_id": 9913, "disease": "", "pathway": " (bta:508990); (R-BTA-114608)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "26342800;27260300;30777067", "class_list": "", "function": "Adipocyte-secreted protein (adipokine) that regulates adipogenesis, metabolism and inflammation through activation of the chemokine-like receptor 1 (CMKLR1). Also acts as a ligand for CMKLR2. Can also bind to C-C chemokine receptor-like 2 (CCRL2), but with a lower affinity than it does to CMKLR1 or CMKLR2. Positively regulates adipocyte differentiation, modulates the expression of adipocyte genes involved in lipid and glucose metabolism and might play a role in angiogenesis, a process essential for the expansion of white adipose tissue. Also acts as a pro-inflammatory adipokine, causing an increase in secretion of pro-inflammatory and prodiabetic adipokines, which further impair adipose tissue metabolic function and have negative systemic effects including impaired insulin sensitivity, altered glucose and lipid metabolism, and a decrease in vascular function in other tissues. Can have both pro- and anti-inflammatory properties depending on the modality of enzymatic cleavage by different classes of proteases. Acts as a chemotactic factor for leukocyte populations expressing CMKLR1, particularly immature plasmacytoid dendritic cells, but also immature myeloid DCs, macrophages and natural killer cells. Exerts an anti-inflammatory role by preventing TNF/TNFA-induced VCAM1 expression and monocytes adhesion in vascular endothelial cells. The effect is mediated via inhibiting activation of NF-kappa-B and CRK/p38 through stimulation of AKT1/NOS3 signaling and nitric oxide production. Exhibits an antimicrobial function in the skin (By similarity)., [UniProtKB, UniProtKB]; Chemerin is a novel regulator of lactogenesis via its own receptor in bovine mammary epithelial cells, [RefSeq, PubMed]; Data show that the fat and energy moblization during lactation influences circulating retinoic acid receptor responder protein 2 (RARRES2) levels as well as the expression of RARRES2 and chemokine-like receptor 1 (CMKLR1) in subcutaneous adipose tissue (SAT) and ovarian cells. Publication Status: Online-Only, [RefSeq, PubMed]; These results suggest that Chemerin promotes lipolysis in mature adipocytes and induces adipogenesis during preadipocyte re-differentiation, further indicating a dual role for Chemerin in the deposition of intramuscular fat in ruminant animals., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005102 signaling receptor binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0005615 extracellular space;GO:0031012 extracellular matrix", "go_biological_process": "GO:0001934 positive regulation of protein phosphorylation;GO:0006935 chemotaxis;GO:0006954 inflammatory response;GO:0030154 cell differentiation;GO:0045087 innate immune response", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q29RS5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q29RT4-1", "uniprot_id": "CDCA2_BOVIN", "mass": 110998.0, "length": 1011, "protein_name": "Cell division cycle-associated protein 2", "gene_name": "CDCA2", "organism": "Bovine", "refseq_name": "cell division cycle-associated protein 2", "refseq_ac": "NP_001039659", "gene_names_uniprotkb": "CDCA2", "gene_names_refseq": "CDCA2", "protein_names_uniprotkb": "Cell division cycle-associated protein 2", "protein_names_refseq": "cell division cycle-associated protein 2", "tax_id": 9913, "disease": "", "pathway": " (bta:515287)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Regulator of chromosome structure during mitosis required for condensin-depleted chromosomes to retain their compact architecture through anaphase. Acts by mediating the recruitment of phosphatase PP1-gamma subunit (PPP1CC) to chromatin at anaphase and into the following interphase. At anaphase onset, its association with chromatin targets a pool of PPP1CC to dephosphorylate substrates (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 14, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0140693 molecular condensate scaffold activity", "go_cellular_component": "GO:0005634 nucleus;GO:0000793 condensed chromosome", "go_biological_process": "GO:0007059 chromosome segregation;GO:0051301 cell division;GO:0007088 regulation of mitotic nuclear division;GO:0051321 meiotic cell cycle", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q29RT4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q29RT8-1", "uniprot_id": "PLPR2_BOVIN", "mass": 41632.0, "length": 389, "protein_name": "Phospholipid phosphatase-related protein type 2", "gene_name": "PLPPR2", "organism": "Bovine", "refseq_name": "phospholipid phosphatase-related protein type 2", "refseq_ac": "NP_001039713", "gene_names_uniprotkb": "PLPPR2; LPPR2; PRG4", "gene_names_refseq": "LPPR2; PLPPR2", "protein_names_uniprotkb": "Phospholipid phosphatase-related protein type 2; Inactive phospholipid phosphatase PLPPR2; Lipid phosphate phosphatase-related protein type 2; PRG-4; Plasticity-related gene 4 protein", "protein_names_refseq": "PRG-4; inactive phospholipid phosphatase PLPPR2; lipid phosphate phosphatase-related protein type 2; phospholipid phosphatase-related protein type 2; plasticity-related gene 4 protein", "tax_id": 9913, "disease": "", "pathway": " (bta:520247)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008195 phosphatidate phosphatase activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007165 signal transduction;GO:0006644 phospholipid metabolic process;GO:0046839 phospholipid dephosphorylation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q29RT8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q29RU1-1", "uniprot_id": "RT12_BOVIN", "mass": 15447.0, "length": 139, "protein_name": "Small ribosomal subunit protein uS12m", "gene_name": "MRPS12", "organism": "Bovine", "refseq_name": "small ribosomal subunit protein uS12m precursor", "refseq_ac": "NP_001070569", "gene_names_uniprotkb": "MRPS12", "gene_names_refseq": "MRPS12", "protein_names_uniprotkb": "Small ribosomal subunit protein uS12m; 28S ribosomal protein S12, mitochondrial; MRP-S12; S12mt", "protein_names_refseq": "28S ribosomal protein S12, mitochondrial; MRP-S12; S12mt; small ribosomal subunit protein uS12m precursor; small ribosomal subunit protein uS12m", "tax_id": 9913, "disease": "", "pathway": " (bta:768042); (R-BTA-5389840); (R-BTA-5419276); (R-BTA-9937383)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "24799711", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005763 mitochondrial small ribosomal subunit;GO:0005743 mitochondrial inner membrane;GO:0005840 ribosome", "go_biological_process": "GO:0006412 translation;GO:0032543 mitochondrial translation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q29RU1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q29RU4-1", "uniprot_id": "CO6_BOVIN", "mass": 104541.0, "length": 932, "protein_name": "Complement component C6", "gene_name": "C6", "organism": "Bovine", "refseq_name": "complement component C6 precursor", "refseq_ac": "NP_001039444", "gene_names_uniprotkb": "C6", "gene_names_refseq": "C6", "protein_names_uniprotkb": "Complement component C6", "protein_names_refseq": "complement component 6; complement component C6 precursor; complement component C6", "tax_id": 9913, "disease": "", "pathway": " (bta:507749)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of the membrane attack complex (MAC), a multiprotein complex activated by the complement cascade, which inserts into a target cell membrane and forms a pore, leading to target cell membrane rupture and cell lysis. The MAC is initiated by proteolytic cleavage of C5 into complement C5b in response to the classical, alternative, lectin and GZMK complement pathways. The complement pathways consist in a cascade of proteins that leads to phagocytosis and breakdown of pathogens and signaling that strengthens the adaptive immune system. Together with component C5b, involved in MAC complex assembly: complement C5b and C6 associate with the outer leaflet of target cell membrane, reducing the energy for membrane bending., [UniProtKB, UniProtKB]", "predicted_glycosites": 10, "predicted_n_glycosites": 2, "predicted_o_glycosites": 2, "predicted_c_glycosites": 6, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 10, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0046872 metal ion binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005579 membrane attack complex;GO:0044218 other organism cell membrane", "go_biological_process": "GO:0031640 killing of cells of another organism;GO:0006958 complement activation, classical pathway;GO:0006956 complement activation;GO:0160257 complement activation, GZMK pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q29RU4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q29RU6-1", "uniprot_id": "G6PC1_BOVIN", "mass": 40827.0, "length": 357, "protein_name": "Glucose-6-phosphatase catalytic subunit 1", "gene_name": "G6PC1", "organism": "Bovine", "refseq_name": "glucose-6-phosphatase catalytic subunit 1", "refseq_ac": "NP_001069592", "gene_names_uniprotkb": "G6PC1; G6PC", "gene_names_refseq": "G6PC1; G6PC", "protein_names_uniprotkb": "Glucose-6-phosphatase catalytic subunit 1; 3.1.3.9; G-6-Pase; G6Pase; Glucose-6-phosphatase", "protein_names_refseq": "G-6-Pase; G6Pase; glucose-6-phosphatase catalytic subunit 1", "tax_id": 9913, "disease": "", "pathway": " (bta:538710); (R-BTA-70263)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Hydrolyzes glucose-6-phosphate to glucose in the endoplasmic reticulum. Forms with the glucose-6-phosphate transporter (SLC37A4/G6PT) the complex responsible for glucose production in the terminal step of glycogenolysis and gluconeogenesis. Hence, it is the key enzyme in homeostatic regulation of blood glucose levels., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.1.3.25;3.1.3.9;3.1.3.94", "go_molecular_function": "GO:0042301 phosphate ion binding;GO:0016773 phosphotransferase activity, alcohol group as acceptor;GO:0004346 glucose-6-phosphatase activity", "go_cellular_component": "GO:0016020 membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006094 gluconeogenesis;GO:0042593 glucose homeostasis;GO:0051156 glucose 6-phosphate metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q29RU6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q29RU9-1", "uniprot_id": "SOX_BOVIN", "mass": 43820.0, "length": 392, "protein_name": "Peroxisomal sarcosine oxidase", "gene_name": "PIPOX", "organism": "Bovine", "refseq_name": "peroxisomal sarcosine oxidase", "refseq_ac": "NP_001014878", "gene_names_uniprotkb": "PIPOX", "gene_names_refseq": "PIPOX", "protein_names_uniprotkb": "Peroxisomal sarcosine oxidase; 1.5.3.1; 1.5.3.7; L-pipecolate oxidase; L-pipecolic acid oxidase; PSO", "protein_names_refseq": "L-pipecolate oxidase; L-pipecolic acid oxidase; PSO; peroxisomal sarcosine oxidase", "tax_id": 9913, "disease": "", "pathway": " (bta:509102); (R-BTA-71064); (R-BTA-9033241)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "Metabolizes sarcosine, L-pipecolic acid and L-proline., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q5E9H6", "ec_number_list": "1.1.1.42;2.3.1.42;5.3.3.21;2.3.2.27;2.3.1.137;2.3.1.7;3.4.21.-;1.1.3.15;1.1.1.35;4.2.1.17;5.3.3.8;1.4.3.3;1.5.3.13;2.5.1.18;1.3.1.38;6.2.1.3;2.3.1.176;2.3.1.16;2.3.1.155;4.1.2.63;1.14.13.39;3.1.2.2;3.1.2.27;3.1.2.1;3.1.2.11;3.1.2.3;3.1.2.5;1.11.1.6;3.4.24.56;4.1.3.4;1.5.3.1;1.5.3.7;3.4.21.53;1.3.3.6", "go_molecular_function": "GO:0050660 flavin adenine dinucleotide binding;GO:0008115 sarcosine oxidase activity;GO:0050031 L-pipecolate oxidase activity", "go_cellular_component": "GO:0005777 peroxisome", "go_biological_process": "GO:0033514 L-lysine catabolic process to acetyl-CoA via L-pipecolate", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q29RU9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q29RV0-1", "uniprot_id": "CDN2D_BOVIN", "mass": 17681.0, "length": 166, "protein_name": "Cyclin-dependent kinase 4 inhibitor D", "gene_name": "CDKN2D", "organism": "Bovine", "refseq_name": "cyclin-dependent kinase 4 inhibitor D", "refseq_ac": "NP_001039515", "gene_names_uniprotkb": "CDKN2D", "gene_names_refseq": "CDKN2D", "protein_names_uniprotkb": "Cyclin-dependent kinase 4 inhibitor D; p19-INK4d", "protein_names_refseq": "cyclin-dependent kinase 4 inhibitor D; cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4); p19-INK4d", "tax_id": 9913, "disease": "", "pathway": " (bta:510244); (R-BTA-2559580); (R-BTA-2559582); (R-BTA-2559585); (R-BTA-69231)", "pathway_count": 5, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Interacts strongly with CDK4 and CDK6 and inhibits them., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0019901 protein kinase binding;GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0097129 cyclin D2-CDK4 complex", "go_biological_process": "GO:0008285 negative regulation of cell population proliferation;GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage;GO:0032526 response to retinoic acid;GO:0030308 negative regulation of cell growth;GO:0009411 response to UV", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q29RV0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q29RV1-1", "uniprot_id": "PDIA4_BOVIN", "mass": 72526.0, "length": 643, "protein_name": "Protein disulfide-isomerase A4", "gene_name": "PDIA4", "organism": "Bovine", "refseq_name": "protein disulfide-isomerase A4 precursor", "refseq_ac": "NP_001039344", "gene_names_uniprotkb": "PDIA4", "gene_names_refseq": "PDIA4", "protein_names_uniprotkb": "Protein disulfide-isomerase A4; 5.3.4.1", "protein_names_refseq": "protein disulfide isomerase related protein; protein disulfide isomerase-associated 4; protein disulfide-isomerase A4 precursor; protein disulfide-isomerase A4", "tax_id": 9913, "disease": "", "pathway": " (bta:415110)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A5D971;Q0V8E1", "ec_number_list": "", "go_molecular_function": "GO:0003756 protein disulfide isomerase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005788 endoplasmic reticulum lumen;GO:0009986 cell surface;GO:0042470 melanosome", "go_biological_process": "GO:0006457 protein folding;GO:0034976 response to endoplasmic reticulum stress", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q29RV1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q29RY7-1", "uniprot_id": "FGL2_BOVIN", "mass": 50684.0, "length": 441, "protein_name": "Fibroleukin", "gene_name": "FGL2", "organism": "Bovine", "refseq_name": "fibroleukin precursor", "refseq_ac": "NP_001039562", "gene_names_uniprotkb": "FGL2", "gene_names_refseq": "FGL2", "protein_names_uniprotkb": "Fibroleukin; Fibrinogen-like protein 2", "protein_names_refseq": "fibrinogen-like protein 2; fibroleukin precursor; fibroleukin", "tax_id": 9913, "disease": "", "pathway": " (bta:511711); (R-BTA-6798695)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "May play a role in physiologic lymphocyte functions at mucosal sites., [UniProtKB]", "predicted_glycosites": 5, "predicted_n_glycosites": 5, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0016504 peptidase activator activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0009986 cell surface;GO:0031012 extracellular matrix", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q29RY7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q29RZ4-1", "uniprot_id": "ZNF2_BOVIN", "mass": 48223.0, "length": 425, "protein_name": "Zinc finger protein 2", "gene_name": "ZNF2", "organism": "Bovine", "refseq_name": "zinc finger protein 2", "refseq_ac": "NP_001039911", "gene_names_uniprotkb": "ZNF2", "gene_names_refseq": "ZNF2", "protein_names_uniprotkb": "Zinc finger protein 2", "protein_names_refseq": "zinc finger protein 2", "tax_id": 9913, "disease": "", "pathway": " (bta:539022)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "May be involved in transcriptional regulation., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006355 regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q29RZ4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q29S03-1", "uniprot_id": "SGCE_BOVIN", "mass": 49889.0, "length": 437, "protein_name": "Epsilon-sarcoglycan", "gene_name": "SGCE", "organism": "Bovine", "refseq_name": "epsilon-sarcoglycan", "refseq_ac": "NP_001068613", "gene_names_uniprotkb": "SGCE", "gene_names_refseq": "SGCE", "protein_names_uniprotkb": "Epsilon-sarcoglycan; Epsilon-SG", "protein_names_refseq": "epsilon-SG; epsilon-sarcoglycan", "tax_id": 9913, "disease": "", "pathway": " (bta:407209)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0005856 cytoskeleton;GO:0005886 plasma membrane;GO:0042383 sarcolemma;GO:0032590 dendrite membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q29S03-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q29S07-1", "uniprot_id": "BRF2_BOVIN", "mass": 46591.0, "length": 421, "protein_name": "Transcription factor IIIB 50 kDa subunit", "gene_name": "BRF2", "organism": "Bovine", "refseq_name": "transcription factor IIIB 50 kDa subunit", "refseq_ac": "NP_001015582", "gene_names_uniprotkb": "BRF2", "gene_names_refseq": "BRF2", "protein_names_uniprotkb": "Transcription factor IIIB 50 kDa subunit; B-related factor 2; BRF-2", "protein_names_refseq": "B-related factor 2; BRF-2; BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit; BRF2, subunit of RNA polymerase III transcription initiation factor, BRF1-like; transcription factor IIIB 50 kDa subunit; zinc finger protein 36, C3H type-like 2", "tax_id": 9913, "disease": "", "pathway": " (bta:512789); (R-BTA-76071)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "General activator of RNA polymerase III transcription. Factor exclusively required for RNA polymerase III transcription of genes with promoter elements upstream of the initiation sites. Contributes to the regulation of gene expression; functions as activator in the absence of oxidative stress. Down-regulates expression of target genes in response to oxidative stress. Overexpression protects cells against apoptosis in response to oxidative stress., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q5E9M2;Q5E9P4;Q5EAB8", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0017025 TBP-class protein binding;GO:0016251 RNA polymerase II general transcription initiation factor activity;GO:0001006 RNA polymerase III type 3 promoter sequence-specific DNA binding", "go_cellular_component": "GO:0097550 transcription preinitiation complex;GO:0005634 nucleus;GO:0005730 nucleolus;GO:0000126 transcription factor TFIIIB complex", "go_biological_process": "GO:0034599 cellular response to oxidative stress;GO:0045945 positive regulation of transcription by RNA polymerase III;GO:0006359 regulation of transcription by RNA polymerase III;GO:0070897 transcription preinitiation complex assembly", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q29S07-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q29S16-1", "uniprot_id": "ABITM_BOVIN", "mass": 20863.0, "length": 187, "protein_name": "Protein Abitram", "gene_name": "ABITRAM", "organism": "Bovine", "refseq_name": "protein Abitram", "refseq_ac": "NP_001039421", "gene_names_uniprotkb": "ABITRAM; FAM206A", "gene_names_refseq": "ABITRAM; C8H9orf6; C9orf6; FAM206A", "protein_names_uniprotkb": "Protein Abitram; Actin-binding transcription modulator; Protein Simiate", "protein_names_refseq": "family with sequence similarity 206 member A; protein Abitram; protein FAM206A; protein Simiate", "tax_id": 9913, "disease": "", "pathway": " (bta:507081)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Actin-binding protein that regulates actin polymerization, filopodia dynamics and increases the branching of proximal dendrites of developing neurons. May play a role in transcription regulation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003785 actin monomer binding;GO:0051015 actin filament binding", "go_cellular_component": "GO:0005634 nucleus;GO:0016607 nuclear speck;GO:0030027 lamellipodium;GO:0030425 dendrite;GO:0030426 growth cone", "go_biological_process": "GO:0048813 dendrite morphogenesis;GO:0051489 regulation of filopodium assembly;GO:0030833 regulation of actin filament polymerization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q29S16-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q29S19-1", "uniprot_id": "BN3D2_BOVIN", "mass": 33490.0, "length": 292, "protein_name": "RNA 5'-monophosphate methyltransferase", "gene_name": "BCDIN3D", "organism": "Bovine", "refseq_name": "RNA 5'-monophosphate methyltransferase", "refseq_ac": "NP_001068684", "gene_names_uniprotkb": "BCDIN3D", "gene_names_refseq": "BCDIN3D", "protein_names_uniprotkb": "RNA 5'-monophosphate methyltransferase; 2.1.1.-; BCDIN3 domain-containing protein", "protein_names_refseq": "BCDIN3 domain-containing protein; RNA 5'-monophosphate methyltransferase; pre-miRNA 5'-monophosphate methyltransferase; probable methyltransferase BCDIN3D", "tax_id": 9913, "disease": "", "pathway": " (bta:505650)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "O-methyltransferase that specifically monomethylates 5'-monophosphate of cytoplasmic histidyl tRNA (tRNA(His)), acting as a capping enzyme by protecting tRNA(His) from cleavage by DICER1. Also able, with less efficiently, to methylate the 5' monophosphate of a subset of pre-miRNAs, acting as a negative regulator of miRNA processing. The 5' monophosphate of pre-miRNAs is recognized by DICER1 and is required for pre-miRNAs processing: methylation at this position reduces the processing of pre-miRNAs by DICER1. Was also reported to mediate dimethylation of pre-miR-145; however dimethylation cannot be reproduced by another group which observes a monomethylation of pre-miR-145., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.1.1.-", "go_molecular_function": "GO:0090486 small RNA 2'-O-methyltransferase activity;GO:0008175 tRNA methyltransferase activity;GO:0008171 O-methyltransferase activity;GO:0008173 RNA methyltransferase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0030488 tRNA methylation;GO:2000632 negative regulation of pre-miRNA processing", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q29S19-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2EGB9-1", "uniprot_id": "ASCL2_BOVIN", "mass": 20264.0, "length": 193, "protein_name": "Achaete-scute homolog 2", "gene_name": "ASCL2", "organism": "Bovine", "refseq_name": "achaete-scute homolog 2", "refseq_ac": "NP_001035697", "gene_names_uniprotkb": "ASCL2; MASH2", "gene_names_refseq": "ASCL2; MASH2", "protein_names_uniprotkb": "Achaete-scute homolog 2; Mash2", "protein_names_refseq": "achaete scute-like protein 2; achaete-scute complex homolog 2; achaete-scute complex-like protein 2; achaete-scute homolog 2", "tax_id": 9913, "disease": "", "pathway": " (bta:664650)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "16503349;24675837;31795267", "class_list": "", "function": "Mash2 is highly conserved across species and is specifically expressed in the bovine placenta. Bovine Mash2 appears to be maternally expressed after implantation, but the paternal genome plays a role in regulating expression., [RefSeq, PubMed]; More DNMT1 mRNA was detected in the transgenic somatic cell nuclear transfer (SCNT) group than the other three groups. Hsp 70.1 mRNA was detected in the in vitro fertilzation embryos. Mash2 mRNA was present at highest levels in transgenic SCNT embryos., [RefSeq, PubMed]; Results indicate that ASCL2 transcription factor binds to the core promoter region of FAM13A and positively regulates its transcription. Publication Status: Online-Only, [RefSeq, PubMed]; Transcription factor. Binds to E-box motifs 5'-CANNTG-3' in the regulatory elements of target genes, probably as a heterodimer with another basic helix-loop-helix (bHLH) protein such as the transcription factor TCF3. May bind both open and closed chromatin, acting as a pioneer transcription factor to allow other factors to bind and activate lineage-specific genes. Required during post-implantation development for the generation of some differentiated trophoblast cell types. Transcriptional activity of ASCL2 may be antagonised in a subset of trophoblast cells by bHLH transcription factor HAND1, perhaps by competing for dimerization with other bHLH proteins. Involved in differentiation and function of follicular T-helper (Tfh) cells, thereby playing a role in germinal center responses; probably modulates expression of genes involved in Tfh cell function, such as BCL6. May also act as a suppressor of Th1-, Th2- and Th17-cell differentiation. Induces the formation of stem cells in intestinal crypts in vitro, synergistically activating transcription of target genes, such as SOX9, together with TCF4/beta-catenin. May form a bistable transcriptional switch, controlling expression of its own gene together with Wnt/R-spondin signaling, and thereby maintaining stem cell characteristics (By similarity). Modulates expression of target genes, including perhaps down-regulating EGR1/Krox24 and chemokine CXCL10/Mob-1 and up-regulating CXCR4 and CDKN1C/p57kip2, in Schwann cells. May play a role in reducing proliferation of Schwann cells, perhaps acting via modulation of expression of CDKN1C (By similarity). May be dispensable for blastocyst formation and later embryonic function (By similarity). May be involved in the determination of neuronal precursors (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q2PJC0", "ec_number_list": "", "go_molecular_function": "GO:0046983 protein dimerization activity;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005737 cytoplasm;GO:0090575 RNA polymerase II transcription regulator complex", "go_biological_process": "GO:2000320 negative regulation of T-helper 17 cell differentiation;GO:0045626 negative regulation of T-helper 1 cell differentiation;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:2000406 positive regulation of T cell migration;GO:0001666 response to hypoxia", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q2EGB9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2EMW0-1", "uniprot_id": "ADIG_BOVIN", "mass": 9696.0, "length": 81, "protein_name": "Adipogenin", "gene_name": "ADIG", "organism": "Bovine", "refseq_name": "adipogenin", "refseq_ac": "NP_001107192", "gene_names_uniprotkb": "ADIG", "gene_names_refseq": "ADIG", "protein_names_uniprotkb": "Adipogenin", "protein_names_refseq": "adipogenin", "tax_id": 9913, "disease": "", "pathway": " (bta:510677)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "27914980", "class_list": "", "function": "Isolated myosatellite cells based on adhesion characteristics to investigate whether ADIG overexpression could promote trans-differentiation and increase fat accumulation in myosatellite cells, [RefSeq, PubMed]; Key regulator of lipid storage that promotes the expansion of lipid droplets during the formation of mature adipocytes (Ref.1). Acts by forming a dodecameric complex with seipin (BSCL2) when adipocytes have differentiated and are undergoing maturation (By similarity). In the dodecameric complex, ADIG antagonizes the activity of BSCL2 by reducing BSCL2-mediated triacylglycerol nucleation and relieving BSCL2's inhibition of GPAT3 and GPAT4 (By similarity). GPAT3 and GPAT4 then translocate to lipid droplets, promoting the synthesis of triacylglycerols and the expansion of lipid droplets (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A7MB91", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005811 lipid droplet;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0007283 spermatogenesis;GO:0045600 positive regulation of fat cell differentiation;GO:0050872 white fat cell differentiation;GO:0050873 brown fat cell differentiation;GO:0019915 lipid storage", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q2EMW0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2HJ19-1", "uniprot_id": "AB17A_BOVIN", "mass": 34102.0, "length": 310, "protein_name": "Alpha/beta hydrolase domain-containing protein 17A", "gene_name": "ABHD17A", "organism": "Bovine", "refseq_name": "alpha/beta hydrolase domain-containing protein 17A", "refseq_ac": "NP_001040001", "gene_names_uniprotkb": "ABHD17A", "gene_names_refseq": "ABHD17A; FAM108A1; FAM108A", "protein_names_uniprotkb": "Alpha/beta hydrolase domain-containing protein 17A; 3.1.2.22; Abhydrolase domain-containing protein 17A", "protein_names_refseq": "abhydrolase domain-containing protein 17A; abhydrolase domain-containing protein FAM108A1; abhydrolase domain-containing protein FAM108A; alpha/beta hydrolase domain-containing protein 17A; family with sequence similarity 108, member A1; protein ABHD17A", "tax_id": 9913, "disease": "", "pathway": " (bta:614425)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Hydrolyzes fatty acids from S-acylated cysteine residues in proteins. Has depalmitoylating activity towards NRAS. Has depalmitoylating activity towards DLG4/PSD95. May have depalmitoylating activity towards MAP6., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.1.2.22;3.1.2.2;3.1.1.93;3.4.19.12;2.3.1.-;3.1.2.-", "go_molecular_function": "GO:0008474 palmitoyl-(protein) hydrolase activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0043197 dendritic spine;GO:0010008 endosome membrane;GO:0098839 postsynaptic density membrane", "go_biological_process": "GO:1905668 positive regulation of protein localization to endosome;GO:0099175 regulation of postsynapse organization;GO:1902817 negative regulation of protein localization to microtubule", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2HJ19-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2HJ22-1", "uniprot_id": "CLD5_BOVIN", "mass": 23017.0, "length": 218, "protein_name": "Claudin-5", "gene_name": "CLDN5", "organism": "Bovine", "refseq_name": "claudin-5", "refseq_ac": "NP_001069928", "gene_names_uniprotkb": "CLDN5", "gene_names_refseq": "CLDN5", "protein_names_uniprotkb": "Claudin-5", "protein_names_refseq": "claudin 5 (transmembrane protein deleted in velocardiofacial syndrome); claudin-5", "tax_id": 9913, "disease": "", "pathway": " (bta:617453)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Plays a major role in tight junction-specific obliteration of the intercellular space., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005198 structural molecule activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005923 bicellular tight junction", "go_biological_process": "GO:0120192 tight junction assembly", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2HJ22-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2HJ63-1", "uniprot_id": "CAHM2_BOVIN", "mass": 36113.0, "length": 323, "protein_name": "Calcium homeostasis modulator protein 2", "gene_name": "CALHM2", "organism": "Bovine", "refseq_name": "calcium homeostasis modulator protein 2", "refseq_ac": "NP_001039885", "gene_names_uniprotkb": "CALHM2", "gene_names_refseq": "CALHM2", "protein_names_uniprotkb": "Calcium homeostasis modulator protein 2; Protein FAM26B", "protein_names_refseq": "calcium homeostasis modulator 2; calcium homeostasis modulator protein 2", "tax_id": 9913, "disease": "", "pathway": " (bta:537067)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Pore-forming subunit of Ca(2+) homeostasis modulator channels. Mediates ATP release from astrocytes and ATP-induced Ca(2+) influx in microglia thus regulating neuronal ATP and Ca(2+) homeostasis, synaptic transmission and neuroinflammatory response. May form intercellular gap junctions. The gating mechanism remains unknown., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005261 monoatomic cation channel activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0043065 positive regulation of apoptotic process;GO:0048167 regulation of synaptic plasticity;GO:0070509 calcium ion import;GO:1903978 regulation of microglial cell activation;GO:1904669 ATP export", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2HJ63-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2HJ66-1", "uniprot_id": "CXG1_BOVIN", "mass": 45553.0, "length": 396, "protein_name": "Gap junction gamma-1 protein", "gene_name": "GJC1", "organism": "Bovine", "refseq_name": "gap junction gamma-1 protein", "refseq_ac": "NP_001039541", "gene_names_uniprotkb": "GJC1; GJA7", "gene_names_refseq": "CXNQ; GJA7; GJC1", "protein_names_uniprotkb": "Gap junction gamma-1 protein; Gap junction alpha-7 protein", "protein_names_refseq": "connexin Q; gap junction alpha-7 protein; gap junction gamma-1 protein; gap junction protein, alpha 7, 45kDa; gap junction protein, delta 3, 31.9kDa; gap junction protein, gamma 1, 45kDa", "tax_id": 9913, "disease": "", "pathway": " (bta:511119); (R-BTA-112303); (R-BTA-190861)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Structural component of the gap junction, a specialized intercellular structure consisting of a cluster of closely packed pairs of transmembrane channels, the connexons, that allow passage of small molecules and electrical signals between neighboring cells. Forms homotypic and heterotypic channels gated by transjunctional voltage (By similarity). Involved in intercellular innate immune signaling. Mediates translocation of 2',3'-cGAMP and 2',5'-oligoadenylates (2-5A) second messengers from virus-infected cells to macrophages and uninfected neighboring cells to propagate and amplify the antiviral immune response (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005216 monoatomic ion channel activity;GO:0086077 gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling;GO:0005243 gap junction channel activity", "go_cellular_component": "GO:0005922 connexin complex", "go_biological_process": "GO:0007267 cell-cell signaling;GO:0045087 innate immune response;GO:0016264 gap junction assembly", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2HJ66-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2HJ69-1", "uniprot_id": "LYSET_BOVIN", "mass": 18880.0, "length": 163, "protein_name": "Lysosomal enzyme trafficking factor", "gene_name": "LYSET", "organism": "Bovine", "refseq_name": "lysosomal enzyme trafficking factor", "refseq_ac": "NP_001070600", "gene_names_uniprotkb": "LYSET; C14orf109; TMEM251", "gene_names_refseq": "C21H14orf109; LYSET; TMEM251", "protein_names_uniprotkb": "Lysosomal enzyme trafficking factor; Transmembrane protein 251", "protein_names_refseq": "UPF0694 transmembrane protein C14orf109 homolog; lysosomal enzyme trafficking factor; transmembrane protein 251", "tax_id": 9913, "disease": "", "pathway": " (bta:768076)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Required for mannose-6-phosphate-dependent trafficking of lysosomal enzymes. LYSET bridges GlcNAc-1-phosphate transferase (GNPTAB), to the membrane-bound transcription factor site-1 protease (MBTPS1), thus allowing proteolytic activation of the GNPTAB. GNPTAB is involved in the regulation of M6P-dependent Golgi-to-lysosome trafficking of lysosomal enzymes. LYSET is thus an essential factor for maturation and delivery of lysosomal hydrolases., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005794 Golgi apparatus", "go_biological_process": "GO:0007040 lysosome organization;GO:0060627 regulation of vesicle-mediated transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2HJ69-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2HJ73-1", "uniprot_id": "HIBCH_BOVIN", "mass": 43349.0, "length": 386, "protein_name": "3-hydroxyisobutyryl-CoA hydrolase, mitochondrial", "gene_name": "HIBCH", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "HIBCH", "gene_names_refseq": "", "protein_names_uniprotkb": "3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; 3-hydroxyisobutyryl-coenzyme A hydrolase; 3.1.2.4; HIB-CoA hydrolase; HIBYL-CoA-H", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite. Has high activity toward isobutyryl-CoA. Could be an isobutyryl-CoA dehydrogenase that functions in valine catabolism. Also hydrolyzes 3-hydroxypropanoyl-CoA (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.1.2.4", "go_molecular_function": "GO:0003860 3-hydroxyisobutyryl-CoA hydrolase activity", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0006574 L-valine catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2HJ73-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2HJ87-1", "uniprot_id": "GMEB1_BOVIN", "mass": 61321.0, "length": 563, "protein_name": "Glucocorticoid modulatory element-binding protein 1", "gene_name": "GMEB1", "organism": "Bovine", "refseq_name": "glucocorticoid modulatory element-binding protein 1", "refseq_ac": "NP_001039940", "gene_names_uniprotkb": "GMEB1", "gene_names_refseq": "GMEB1", "protein_names_uniprotkb": "Glucocorticoid modulatory element-binding protein 1; GMEB-1", "protein_names_refseq": "GMEB-1; glucocorticoid modulatory element-binding protein 1", "tax_id": 9913, "disease": "", "pathway": " (bta:540374)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Acts as a DNA-binding transcriptional regulator involved in modulating the expression of genes responsive to glucocorticoid signaling. Specifically binds AT-rich DNA motifs known as glucocorticoid modulatory elements (GMEs), repressing or enhancing transcription depending on cellular context. Forms heterodimeric complexes with GMEB2, which enhances its DNA-binding specificity and transcriptional activity. This complex plays a critical role in the repression of glucocorticoid receptor (GR/NR3C1) transcriptional activity, acting as a negative modulator of glucocorticoid signaling (By similarity). Regulates dopamine-enriched midbrain genes, including tyrosine hydroxylase/TH and the dopamine transporter SLC6A3, essential for dopamine signaling (By similarity). Also binds the transferrin receptor promoter. In the cytoplasm, inhibits caspase activation and neuronal apoptosis by stabilizing CFLARL and blocking pro-caspase 8 activation (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0046872 metal ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2HJ87-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2HJA9-1", "uniprot_id": "PHLP_BOVIN", "mass": 34395.0, "length": 301, "protein_name": "Phosducin-like protein", "gene_name": "PDCL", "organism": "Bovine", "refseq_name": "phosducin-like protein", "refseq_ac": "NP_777184", "gene_names_uniprotkb": "PDCL", "gene_names_refseq": "PDCL", "protein_names_uniprotkb": "Phosducin-like protein; PHLP", "protein_names_refseq": "PHLP; phosducin-like protein", "tax_id": 9913, "disease": "", "pathway": " (bta:286773); (R-BTA-6814122)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "16415341", "class_list": "", "function": "Antagonistic actions of PhLP3 and prefoldin serve to modulate CCT activity and play a key role in establishing a functional cytoskeleton in vivo, [RefSeq, PubMed]; Functions as a co-chaperone for CCT in the assembly of heterotrimeric G protein complexes, facilitates the assembly of both Gbeta-Ggamma and RGS-Gbeta5 heterodimers. Also acts as a positive regulator of hedgehog signaling and regulates ciliary function., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005929 cilium", "go_biological_process": "GO:0045880 positive regulation of smoothened signaling pathway;GO:0007601 visual perception;GO:0030030 cell projection organization;GO:1902605 heterotrimeric G-protein complex assembly;GO:0008277 regulation of G protein-coupled receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q2HJA9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2HJB0-1", "uniprot_id": "MBLC1_BOVIN", "mass": 27287.0, "length": 263, "protein_name": "Metallo-beta-lactamase domain-containing protein 1", "gene_name": "MBLAC1", "organism": "Bovine", "refseq_name": "metallo-beta-lactamase domain-containing protein 1", "refseq_ac": "NP_001068680", "gene_names_uniprotkb": "MBLAC1", "gene_names_refseq": "MBLAC1", "protein_names_uniprotkb": "Metallo-beta-lactamase domain-containing protein 1; 3.1.27.-; Endoribonuclease MBLAC1", "protein_names_refseq": "endoribonuclease MBLAC1; metallo-beta-lactamase domain-containing protein 1", "tax_id": 9913, "disease": "", "pathway": " (bta:505636)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Endoribonuclease that catalyzes the hydrolysis of histone-coding pre-mRNA 3'-end. Involved in histone pre-mRNA processing during the S-phase of the cell cycle, which is required for entering/progressing through S-phase. Cleaves histone pre-mRNA at a major and a minor cleavage site after the 5'-ACCCA-3' and the 5'-ACCCACA-3' sequence, respectively, and located downstream of the stem-loop. May require the presence of the HDE element located at the histone pre-RNA 3'-end to avoid non-specific cleavage., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.1.27.-", "go_molecular_function": "GO:0016787 hydrolase activity;GO:0046872 metal ion binding;GO:0004521 RNA endonuclease activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:1900087 positive regulation of G1/S transition of mitotic cell cycle;GO:0008334 histone mRNA metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2HJB0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2HJB9-1", "uniprot_id": "TMM98_BOVIN", "mass": 24572.0, "length": 226, "protein_name": "Transmembrane protein 98", "gene_name": "TMEM98", "organism": "Bovine", "refseq_name": "transmembrane protein 98", "refseq_ac": "NP_001039611", "gene_names_uniprotkb": "TMEM98", "gene_names_refseq": "TMEM98", "protein_names_uniprotkb": "Transmembrane protein 98", "protein_names_refseq": "transmembrane protein 98", "tax_id": 9913, "disease": "", "pathway": " (bta:513445)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Functions as a negative regulator of MYRF in oligodendrocyte differentiation and myelination. Interacts with the C-terminal of MYRF inhibiting MYRF self-cleavage and N-fragment nuclear translocation. The secreted form promotes differentiation of T helper 1 cells (Th1)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005615 extracellular space;GO:0005783 endoplasmic reticulum;GO:0005886 plasma membrane;GO:0070062 extracellular exosome;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0045063 T-helper 1 cell differentiation;GO:1900181 negative regulation of protein localization to nucleus;GO:0031642 negative regulation of myelination;GO:0048715 negative regulation of oligodendrocyte differentiation;GO:0010955 negative regulation of protein processing", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2HJB9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2HJC0-1", "uniprot_id": "NGRN_BOVIN", "mass": 31741.0, "length": 287, "protein_name": "Neugrin", "gene_name": "NGRN", "organism": "Bovine", "refseq_name": "neugrin precursor", "refseq_ac": "NP_001039457", "gene_names_uniprotkb": "NGRN", "gene_names_refseq": "NGRN", "protein_names_uniprotkb": "Neugrin; Neurite outgrowth-associated protein", "protein_names_refseq": "neugrin precursor; neurite outgrowth-associated protein", "tax_id": 9913, "disease": "", "pathway": " (bta:508115)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Plays an essential role in mitochondrial ribosome biogenesis. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation of core subunits of the oxidative phosphorylation system., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0019843 rRNA binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0005634 nucleus;GO:0031966 mitochondrial membrane", "go_biological_process": "GO:0030154 cell differentiation;GO:0070131 positive regulation of mitochondrial translation;GO:0061668 mitochondrial ribosome assembly", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2HJC0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2HJG2-1", "uniprot_id": "PUF60_BOVIN", "mass": 57087.0, "length": 530, "protein_name": "Poly(U)-binding-splicing factor PUF60", "gene_name": "PUF60", "organism": "Bovine", "refseq_name": "poly(U)-binding-splicing factor PUF60 isoform 3", "refseq_ac": "NP_001039598", "gene_names_uniprotkb": "PUF60; Siahbp1", "gene_names_refseq": "PUF60", "protein_names_uniprotkb": "Poly(U)-binding-splicing factor PUF60; 60 kDa poly(U)-binding-splicing factor", "protein_names_refseq": "60 kDa poly(U)-binding-splicing factor; poly(U)-binding-splicing factor PUF60 isoform 3; poly(U)-binding-splicing factor PUF60; poly-U binding splicing factor 60KDa", "tax_id": 9913, "disease": "", "pathway": " (bta:512824)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "DNA- and RNA-binding protein, involved in several nuclear processes such as pre-mRNA splicing, apoptosis and transcription regulation. In association with FUBP1 regulates MYC transcription at the P2 promoter through the core-TFIIH basal transcription factor. Acts as a transcriptional repressor through the core-TFIIH basal transcription factor. Represses FUBP1-induced transcriptional activation but not basal transcription. Decreases ERCC3 helicase activity. Is also involved in pre-mRNA splicing. Promotes splicing of an intron with weak 3'-splice site and pyrimidine tract in a cooperative manner with U2AF2. Involved in apoptosis induction when overexpressed in HeLa cells. Modulates alternative splicing of several mRNAs. Binds to relaxed DNA of active promoter regions. Binds to the pyrimidine tract and 3'-splice site regions of pre-mRNA; binding is enhanced in presence of U2AF2. Binds to Y5 RNA in association with RO60. Binds to poly(U) RNA (By similarity)., [UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0003723 RNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:1990904 ribonucleoprotein complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006915 apoptotic process;GO:0006376 mRNA splice site recognition;GO:0000380 alternative mRNA splicing, via spliceosome;GO:0000381 regulation of alternative mRNA splicing, via spliceosome", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2HJG2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2HJG4-1", "uniprot_id": "TDRD3_BOVIN", "mass": 80808.0, "length": 722, "protein_name": "Tudor domain-containing protein 3", "gene_name": "TDRD3", "organism": "Bovine", "refseq_name": "tudor domain-containing protein 3", "refseq_ac": "NP_001039891", "gene_names_uniprotkb": "TDRD3", "gene_names_refseq": "TDRD3", "protein_names_uniprotkb": "Tudor domain-containing protein 3", "protein_names_refseq": "tudor domain-containing protein 3", "tax_id": 9913, "disease": "", "pathway": " (bta:537918)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Scaffolding protein that specifically recognizes and binds dimethylarginine-containing proteins. Plays a role in the regulation of translation of target mRNAs by binding Arg/Gly-rich motifs (GAR) in dimethylarginine-containing proteins. In nucleus, acts as a coactivator: recognizes and binds asymmetric dimethylation on the core histone tails associated with transcriptional activation (H3R17me2a and H4R3me2a) and recruits proteins at these arginine-methylated loci. In cytoplasm, acts as an antiviral factor that participates in the assembly of stress granules together with G3BP1., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003682 chromatin binding;GO:0003713 transcription coactivator activity;GO:0003723 RNA binding;GO:0140008 histone H4 reader activity;GO:0140006 histone H3 reader activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0140225 DNA topoisomerase III-beta-TDRD3 complex", "go_biological_process": "GO:0141194 siRNA-mediated heterochromatin formation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2HJG4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2HJG5-1", "uniprot_id": "VPS35_BOVIN", "mass": 91751.0, "length": 796, "protein_name": "Vacuolar protein sorting-associated protein 35", "gene_name": "VPS35", "organism": "Bovine", "refseq_name": "vacuolar protein sorting-associated protein 35", "refseq_ac": "NP_001039723", "gene_names_uniprotkb": "VPS35", "gene_names_refseq": "VPS35", "protein_names_uniprotkb": "Vacuolar protein sorting-associated protein 35; Vesicle protein sorting 35", "protein_names_refseq": "vacuolar protein sorting 35 homolog; vacuolar protein sorting-associated protein 35; vesicle protein sorting 35", "tax_id": 9913, "disease": "", "pathway": " (bta:521864); (R-BTA-3238698)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "30573663", "class_list": "", "function": "Acts as a component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. The recruitment of the CSC to the endosomal membrane involves RAB7A and SNX3. The CSC seems to associate with the cytoplasmic domain of cargo proteins predominantly via VPS35; however, these interactions seem to be of low affinity and retromer SNX proteins may also contribute to cargo selectivity thus questioning the classical function of the CSC. The SNX-BAR retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN) and is involved in endosome-to-plasma membrane transport for cargo protein recycling. The SNX3-retromer mediates the retrograde endosome-to-TGN transport of WLS distinct from the SNX-BAR retromer pathway. The SNX27-retromer is believed to be involved in endosome-to-plasma membrane trafficking and recycling of a broad spectrum of cargo proteins. The CSC seems to act as recruitment hub for other proteins, such as the WASH complex and TBC1D5. Required for retrograde transport of lysosomal enzyme receptor IGF2R and SLC11A2. Required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Required for endosomal localization of WASHC2. Mediates the association of the CSC with the WASH complex via WASHC2. Required for the endosomal localization of TBC1D5 (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0031748 D1 dopamine receptor binding", "go_cellular_component": "GO:0030906 retromer, cargo-selective complex;GO:0099073 mitochondrion-derived vesicle;GO:0005739 mitochondrion;GO:0005768 endosome;GO:0005769 early endosome", "go_biological_process": "GO:2000331 regulation of terminal button organization;GO:0099639 neurotransmitter receptor transport, endosome to plasma membrane;GO:0006886 intracellular protein transport;GO:0010628 positive regulation of gene expression;GO:1902950 regulation of dendritic spine maintenance", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q2HJG5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2HJJ0-1", "uniprot_id": "KLC4_BOVIN", "mass": 68220.0, "length": 616, "protein_name": "Kinesin light chain 4", "gene_name": "KLC4", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "KLC4; KNSL8", "gene_names_refseq": "", "protein_names_uniprotkb": "Kinesin light chain 4; KLC 4; Kinesin-like protein 8", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport. The light chain may function in coupling of cargo to the heavy chain or in the modulation of its ATPase activity (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0019894 kinesin binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005874 microtubule;GO:0005871 kinesin complex", "go_biological_process": "GO:0007018 microtubule-based movement", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2HJJ0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2HJM9-1", "uniprot_id": "MEST_BOVIN", "mass": 38724.0, "length": 335, "protein_name": "Mesoderm-specific transcript homolog protein", "gene_name": "MEST", "organism": "Bovine", "refseq_name": "mesoderm-specific transcript homolog protein", "refseq_ac": "NP_001076837", "gene_names_uniprotkb": "MEST; PEG1", "gene_names_refseq": "MEST; PEG1", "protein_names_uniprotkb": "Mesoderm-specific transcript homolog protein; 3.-.-.-; Paternally-expressed gene 1 protein", "protein_names_refseq": "mesoderm specific transcript homolog; mesoderm-specific transcript homolog protein; paternally-expressed gene 1 protein", "tax_id": 9913, "disease": "", "pathway": " (bta:404180)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "14668210", "class_list": "", "function": "Plays an important role in enabling neurons to transition from bipolar to multipolar shapes, a process essential for their correct migration toward the cortical plate during brain development. This function is likely achieved through the regulation of N-cadherin-dependent cell adhesion and the modulation of Akt and canonical Wnt signaling pathways. Essential for the development and maintenance of meso-diencephalic dopaminergic (mdDA) neurons during development. Negatively regulates the canonical Wnt signaling pathway during adipogenic differentiation by reducing the glycosylation, maturation, and cell membrane localization of the Wnt coreceptor LRP6., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A3KN56;Q6U8D3;Q6U8D4", "ec_number_list": "", "go_molecular_function": "GO:0016787 hydrolase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0090090 negative regulation of canonical Wnt signaling pathway;GO:0045444 fat cell differentiation;GO:1903077 negative regulation of protein localization to plasma membrane;GO:0048666 neuron development;GO:0050767 regulation of neurogenesis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q2HJM9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KHT7-1", "uniprot_id": "RS27_BOVIN", "mass": 9461.0, "length": 84, "protein_name": "Small ribosomal subunit protein eS27", "gene_name": "RPS27", "organism": "Bovine", "refseq_name": "small ribosomal subunit protein eS27", "refseq_ac": "NP_001091604", "gene_names_uniprotkb": "RPS27", "gene_names_refseq": "RPS27", "protein_names_uniprotkb": "Small ribosomal subunit protein eS27; 40S ribosomal protein S27", "protein_names_refseq": "40S ribosomal protein S27; metallopanstimulin 1; small ribosomal subunit protein eS27", "tax_id": 9913, "disease": "", "pathway": " (bta:615638); (R-BTA-141430); (R-BTA-141444); (R-BTA-156827); (R-BTA-1799339); (R-BTA-2467813); (R-BTA-2500257); (R-BTA-5663220); (R-BTA-6791226); (R-BTA-72649); (R-BTA-72689); (R-BTA-72695); (R-BTA-72702); (R-BTA-72706); (R-BTA-9648025); (R-BTA-975956); (R-BTA-975957); (R-BTA-9954714); (R-BTA-9954716)", "pathway_count": 19, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of the small ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. Required for proper rRNA processing and maturation of 18S rRNAs. Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A1XEE0", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding;GO:0008270 zinc ion binding;GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0032040 small-subunit processome;GO:0022627 cytosolic small ribosomal subunit", "go_biological_process": "GO:0006412 translation;GO:0006364 rRNA processing;GO:0042274 ribosomal small subunit biogenesis;GO:0000028 ribosomal small subunit assembly", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2KHT7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KHU0-1", "uniprot_id": "SERB_BOVIN", "mass": 24850.0, "length": 225, "protein_name": "Phosphoserine phosphatase", "gene_name": "PSPH", "organism": "Bovine", "refseq_name": "phosphoserine phosphatase", "refseq_ac": "NP_001039820", "gene_names_uniprotkb": "PSPH", "gene_names_refseq": "PSPH", "protein_names_uniprotkb": "Phosphoserine phosphatase; 3.1.3.3; O-phosphoserine phosphohydrolase; PSPase; PSP", "protein_names_refseq": "L-3-phosphoserine phosphatase; O-phosphoserine phosphohydrolase; PSPase; PSP; phosphoserine phosphatase", "tax_id": 9913, "disease": "", "pathway": " (bta:533630); (R-BTA-977347)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalyzes the last irreversible step in the biosynthesis of L-serine from carbohydrates, the dephosphorylation of O-phospho-L-serine to L-serine. L-serine can then be used in protein synthesis, to produce other amino acids, in nucleotide metabolism or in glutathione synthesis, or can be racemized to D-serine, a neuromodulator. May also act on O-phospho-D-serine., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.1.3.3", "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0036424 L-phosphoserine phosphatase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0006563 L-serine metabolic process;GO:0006564 L-serine biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2KHU0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KHV5-1", "uniprot_id": "NDUF7_BOVIN", "mass": 49265.0, "length": 441, "protein_name": "Protein arginine methyltransferase NDUFAF7, mitochondrial", "gene_name": "NDUFAF7", "organism": "Bovine", "refseq_name": "protein arginine methyltransferase NDUFAF7, mitochondrial precursor", "refseq_ac": "NP_001094519", "gene_names_uniprotkb": "NDUFAF7", "gene_names_refseq": "C11H2orf56; NDUFAF7", "protein_names_uniprotkb": "Protein arginine methyltransferase NDUFAF7, mitochondrial; 2.1.1.320; NADH dehydrogenase [ubiquinone] complex I, assembly factor 7; Protein midA homolog", "protein_names_refseq": "NADH dehydrogenase (ubiquinone) complex I, assembly factor 7; NADH dehydrogenase [ubiquinone] complex I, assembly factor 7; protein arginine methyltransferase NDUFAF7, mitochondrial precursor; protein arginine methyltransferase NDUFAF7, mitochondrial; protein midA homolog, mitochondrial", "tax_id": 9913, "disease": "", "pathway": " (bta:504290)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I). Acts by mediating symmetric dimethylation of 'Arg-118' of NDUFS2 after it assembles into the complex I, stabilizing the early intermediate complex., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A6QQB0", "ec_number_list": "2.1.1.320", "go_molecular_function": "GO:0035243 protein-arginine omega-N symmetric methyltransferase activity", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine;GO:0032981 mitochondrial respiratory chain complex I assembly", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2KHV5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KHX6-1", "uniprot_id": "CRYM_BOVIN", "mass": 33747.0, "length": 314, "protein_name": "Ketimine reductase mu-crystallin", "gene_name": "CRYM", "organism": "Bovine", "refseq_name": "ketimine reductase mu-crystallin", "refseq_ac": "NP_001039379", "gene_names_uniprotkb": "CRYM", "gene_names_refseq": "CRYM", "protein_names_uniprotkb": "Ketimine reductase mu-crystallin; 1-piperideine-2-carboxylate/1-pyrroline-2-carboxylate reductase; 1.5.1.1; 1.5.1.25; NADP-regulated thyroid-hormone-binding protein; P2C/Pyr2C reductase", "protein_names_refseq": "1-piperideine-2-carboxylate/1-pyrroline-2-carboxylate reductase; NADP-regulated thyroid-hormone-binding protein; P2C/Pyr2C reductase; ketimine reductase mu-crystallin; mu-crystallin homolog; thiomorpholine-carboxylate dehydrogenase", "tax_id": 9913, "disease": "", "pathway": " (bta:505167); (R-BTA-71064)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "3191146", "class_list": "", "function": "Catalyzes the NAD(P)H-dependent reduction of imine double bonds of a number of cyclic ketimine substrates, including sulfur-containing cyclic ketimines (PubMed:3191146). Under physiological conditions, it efficiently catalyzes delta(1)-piperideine-2-carboxylate (P2C) and delta(1)-pyrroline-2-carboxylate (Pyr2C) reduction, suggesting a central role in lysine and glutamate metabolism. Additional substrates are (S)-cystathionine ketimine (CysK), 3,4-dehydrothiomorpholine-3-carboxylate (AECK), and (R)-lanthionine ketimine (LK) that is reduced at very low rate compared to other substrates (PubMed:3191146). Also catalyzes the NAD(P)H-dependent reduction of delta(2)-thiazoline-2-carboxylate (T2C) (By similarity)., [UniProtKB, PubMed, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.5.1.25;1.5.1.1", "go_molecular_function": "GO:0047127 thiomorpholine-carboxylate dehydrogenase activity;GO:0070324 thyroid hormone binding;GO:0050241 pyrroline-2-carboxylate reductase activity;GO:0047125 delta1-piperideine-2-carboxylate reductase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0042403 thyroid hormone metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q2KHX6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KHZ2-1", "uniprot_id": "HBS1L_BOVIN", "mass": 75850.0, "length": 686, "protein_name": "HBS1-like protein", "gene_name": "HBS1L", "organism": "Bovine", "refseq_name": "HBS1-like protein", "refseq_ac": "NP_001039963", "gene_names_uniprotkb": "HBS1L", "gene_names_refseq": "HBS1L", "protein_names_uniprotkb": "HBS1-like protein; 3.6.5.-", "protein_names_refseq": "HBS1-like protein", "tax_id": 9913, "disease": "", "pathway": " (bta:541083)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "GTPase component of the Pelota-HBS1L complex, a complex that recognizes stalled ribosomes and triggers the No-Go Decay (NGD) pathway. The Pelota-HBS1L complex recognizes ribosomes stalled at the 3' end of an mRNA and engages stalled ribosomes by destabilizing mRNA in the mRNA channel. Following mRNA extraction from stalled ribosomes by the SKI complex, the Pelota-HBS1L complex promotes recruitment of ABCE1, which drives the disassembly of stalled ribosomes, followed by degradation of damaged mRNAs as part of the NGD pathway., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.6.5.2;3.6.5.5;3.6.5.-;3.6.5.3;2.7.11.1;3.6.1.5;3.6.1.15;3.6.5.4", "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0003746 translation elongation factor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:1990533 Dom34-Hbs1 complex", "go_biological_process": "GO:0032790 ribosome disassembly;GO:0006417 regulation of translation;GO:0006412 translation;GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2KHZ2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KI11-1", "uniprot_id": "SCN3B_BOVIN", "mass": 24636.0, "length": 215, "protein_name": "Sodium channel regulatory subunit beta-3", "gene_name": "SCN3B", "organism": "Bovine", "refseq_name": "sodium channel regulatory subunit beta-3 precursor", "refseq_ac": "NP_001039960", "gene_names_uniprotkb": "SCN3B", "gene_names_refseq": "SCN3B", "protein_names_uniprotkb": "Sodium channel regulatory subunit beta-3", "protein_names_refseq": "sodium channel regulatory subunit beta-3 precursor; sodium channel regulatory subunit beta-3; sodium channel subunit beta-3; sodium channel, voltage-gated, type III, beta subunit", "tax_id": 9913, "disease": "", "pathway": " (bta:540925); (R-BTA-5576892)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Regulatory subunit of multiple voltage-gated sodium (Nav) channels directly mediating the depolarization of excitable membranes. Navs, also called VGSCs (voltage-gated sodium channels) or VDSCs (voltage-dependent sodium channels), operate by switching between closed and open conformations depending on the voltage difference across the membrane. In the open conformation they allow Na(+) ions to selectively pass through the pore, along their electrochemical gradient. The influx of Na+ ions provokes membrane depolarization, initiating the propagation of electrical signals throughout cells and tissues. The accessory beta subunits participate in localization and functional modulation of the Nav channels (By similarity). Modulates the activity of SCN2A/Nav1.2, causing a hyperpolarizing shift in the voltage-dependence of inactivation of the channel and increasing the fraction of channels operating in the fast gating mode (By similarity). Modulates the activity of SCN5A/Nav1.5. Could also regulate the atypical sodium channel SCN7A/Nav2.1. Modulates the activity of SCN10A/Nav1.8, regulating its oligomerization and accelerating the recovery from inactivation (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 4, "predicted_n_glycosites": 4, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0019871 sodium channel inhibitor activity;GO:0017080 sodium channel regulator activity;GO:0044325 transmembrane transporter binding;GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential", "go_cellular_component": "GO:0005886 plasma membrane;GO:0030018 Z disc;GO:0001518 voltage-gated sodium channel complex", "go_biological_process": "GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization;GO:0072659 protein localization to plasma membrane;GO:0086091 regulation of heart rate by cardiac conduction;GO:0010460 positive regulation of heart rate;GO:0035725 sodium ion transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2KI11-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KI15-1", "uniprot_id": "RF1ML_BOVIN", "mass": 43523.0, "length": 380, "protein_name": "Peptide chain release factor 1-like, mitochondrial", "gene_name": "MTRF1L", "organism": "Bovine", "refseq_name": "peptide chain release factor 1-like, mitochondrial precursor", "refseq_ac": "NP_001039843", "gene_names_uniprotkb": "MTRF1L", "gene_names_refseq": "MTRF1L", "protein_names_uniprotkb": "Peptide chain release factor 1-like, mitochondrial; Mitochondrial translational release factor 1-like", "protein_names_refseq": "mitochondrial translational release factor 1 like; peptide chain release factor 1-like, mitochondrial precursor; peptide chain release factor 1-like, mitochondrial", "tax_id": 9913, "disease": "", "pathway": " (bta:534354)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Mitochondrial peptide chain release factor that directs the termination of translation in response to the peptide chain termination codons UAA and UAG., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003747 translation release factor activity;GO:0016149 translation release factor activity, codon specific", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0070126 mitochondrial translational termination", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2KI15-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KI23-1", "uniprot_id": "MINY2_BOVIN", "mass": 68118.0, "length": 630, "protein_name": "Ubiquitin carboxyl-terminal hydrolase MINDY-2", "gene_name": "MINDY2", "organism": "Bovine", "refseq_name": "ubiquitin carboxyl-terminal hydrolase MINDY-2", "refseq_ac": "NP_001039740", "gene_names_uniprotkb": "MINDY2; FAM63B", "gene_names_refseq": "FAM63B; MINDY2", "protein_names_uniprotkb": "Ubiquitin carboxyl-terminal hydrolase MINDY-2; 3.4.19.12; Deubiquitinating enzyme MINDY-2; Protein FAM63B", "protein_names_refseq": "deubiquitinating enzyme MINDY-2; family with sequence similarity 63 member B; protein FAM63B; ubiquitin carboxyl-terminal hydrolase MINDY-2", "tax_id": 9913, "disease": "", "pathway": " (bta:524749)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Hydrolase that can remove 'Lys-48'-linked conjugated ubiquitin from proteins. Can also bind to polyubiquitin chains of different linkage types, including 'Lys-6', 'Lys-11', 'Lys-29', 'Lys-33' and 'Lys-63'. May play a regulatory role at the level of protein turnover., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0036435 K48-linked polyubiquitin modification-dependent protein binding;GO:0016807 cysteine-type carboxypeptidase activity;GO:0071795 K11-linked polyubiquitin modification-dependent protein binding;GO:0071796 K6-linked polyubiquitin modification-dependent protein binding;GO:0070530 K63-linked polyubiquitin modification-dependent protein binding", "go_cellular_component": "GO:0005654 nucleoplasm", "go_biological_process": "GO:0006508 proteolysis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2KI23-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KI39-1", "uniprot_id": "SPIN2_BOVIN", "mass": 29807.0, "length": 258, "protein_name": "Spindlin-2", "gene_name": "SPIN2", "organism": "Bovine", "refseq_name": "spindlin-2", "refseq_ac": "NP_001073238", "gene_names_uniprotkb": "SPIN2", "gene_names_refseq": "SPIN2", "protein_names_uniprotkb": "Spindlin-2; SPIN-2; Spindlin-like protein 2", "protein_names_refseq": "SPIN-2; spindlin-2; spindlin-like protein 2", "tax_id": 9913, "disease": "", "pathway": " (bta:506451)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "May be involved in the regulation of cell cycle progression. Exhibits H3K4me3-binding activity., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0140002 histone H3K4me3 reader activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0006355 regulation of DNA-templated transcription;GO:0007276 gamete generation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2KI39-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KI58-1", "uniprot_id": "ZN181_BOVIN", "mass": 65934.0, "length": 570, "protein_name": "Zinc finger protein 181", "gene_name": "ZNF181", "organism": "Bovine", "refseq_name": "zinc finger protein 181", "refseq_ac": "NP_001070017", "gene_names_uniprotkb": "ZNF181", "gene_names_refseq": "ZNF181", "protein_names_uniprotkb": "Zinc finger protein 181", "protein_names_refseq": "zinc finger protein 181", "tax_id": 9913, "disease": "", "pathway": " (bta:767826); (R-BTA-212436)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "May be involved in transcriptional regulation., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2KI58-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KI74-1", "uniprot_id": "TRADD_BOVIN", "mass": 34292.0, "length": 312, "protein_name": "Tumor necrosis factor receptor type 1-associated DEATH domain protein", "gene_name": "TRADD", "organism": "Bovine", "refseq_name": "tumor necrosis factor receptor type 1-associated DEATH domain protein", "refseq_ac": "NP_001039361", "gene_names_uniprotkb": "TRADD", "gene_names_refseq": "TRADD", "protein_names_uniprotkb": "Tumor necrosis factor receptor type 1-associated DEATH domain protein; TNFR1-associated DEATH domain protein; TNFRSF1A-associated via death domain", "protein_names_refseq": "TNFR1-associated DEATH domain protein; tumor necrosis factor receptor type 1-associated DEATH domain protein", "tax_id": 9913, "disease": "", "pathway": " (bta:504707); (R-BTA-3371378); (R-BTA-5218900); (R-BTA-5357786); (R-BTA-5357905); (R-BTA-5357956); (R-BTA-5675482); (R-BTA-69416); (R-BTA-75893)", "pathway_count": 9, "publication_count": 1, "publication_id_list": "15310755", "class_list": "", "function": "Adapter molecule for TNFRSF1A/TNFR1 that specifically associates with the cytoplasmic domain of activated TNFRSF1A/TNFR1 mediating its interaction with FADD. Overexpression of TRADD leads to two major TNF-induced responses, apoptosis and activation of NF-kappa-B (By similarity). The nuclear form acts as a tumor suppressor by preventing ubiquitination and degradation of isoform p19ARF/ARF of CDKN2A by TRIP12: acts by interacting with TRIP12, leading to disrupt interaction between TRIP12 and isoform p19ARF/ARF of CDKN2A (By similarity)., [UniProtKB, UniProtKB, UniProtKB]; TNF binding induces release of AIP1 (DAB2IP) from TNFR1, resulting in cytoplasmic translocation and concomitant formation of an intracellular signaling complex comprised of TRADD, RIP1, TRAF2, and AIPl., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0070513 death domain binding;GO:0042802 identical protein binding;GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005856 cytoskeleton;GO:0005886 plasma membrane;GO:0002947 tumor necrosis factor receptor superfamily complex", "go_biological_process": "GO:0030335 positive regulation of cell migration;GO:0043123 positive regulation of canonical NF-kappaB signal transduction;GO:0050729 positive regulation of inflammatory response;GO:0097191 extrinsic apoptotic signaling pathway;GO:0007249 canonical NF-kappaB signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q2KI74-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KI76-1", "uniprot_id": "SELS_BOVIN", "mass": 21385.0, "length": 190, "protein_name": "Selenoprotein S", "gene_name": "SELENOS", "organism": "Bovine", "refseq_name": "selenoprotein S isoform 1", "refseq_ac": "NP_001039579", "gene_names_uniprotkb": "SELENOS", "gene_names_refseq": "SELENOS; SELS; VIMP", "protein_names_uniprotkb": "Selenoprotein S; SelS", "protein_names_refseq": "VCP interacting membrane selenoprotein; VCP-interacting membrane protein; selenoprotein S isoform 1", "tax_id": 9913, "disease": "", "pathway": " (bta:512276)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Involved in the degradation process of misfolded endoplasmic reticulum (ER) luminal proteins. Participates in the transfer of misfolded proteins from the ER to the cytosol, where they are destroyed by the proteasome in a ubiquitin-dependent manner. Probably acts by serving as a linker between DERL1, which mediates the retrotranslocation of misfolded proteins into the cytosol, and the ATPase complex VCP, which mediates the translocation and ubiquitination (By similarity)., [UniProtKB]; This gene encodes a transmembrane protein that is localized in the endoplasmic reticulum (ER). It is involved in the degradation process of misfolded proteins in the ER, and may also have a role in inflammation control. This protein is a selenoprotein, containing the rare amino acid selenocysteine (Sec). Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. Two additional phylogenetically conserved stem-loop structures (Stem-loop 1 and Stem-loop 2) in the 3' UTR of this mRNA have been shown to function as modulators of Sec insertion (PMID:23614019). Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2017]., [RefSeq]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0036502 Derlin-1-VIMP complex;GO:0036513 Derlin-1 retrotranslocation complex;GO:0005881 cytoplasmic microtubule", "go_biological_process": "GO:0030968 endoplasmic reticulum unfolded protein response;GO:0030970 retrograde protein transport, ER to cytosol", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2KI76-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KI97-1", "uniprot_id": "GPR84_BOVIN", "mass": 43517.0, "length": 396, "protein_name": "G protein-coupled receptor 84", "gene_name": "GPR84", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "GPR84", "gene_names_refseq": "", "protein_names_uniprotkb": "G protein-coupled receptor 84", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": " (R-BTA-418555); (R-BTA-6798695)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "G protein-coupled receptor that responds endogenously to dietary fatty acids or nutrient, specifically medium-chain free fatty acid (FFA) with carbon chain lengths of C9 to C14. Capric acid (C10:0), undecanoic acid (C11:0) and lauric acid (C12:0) are the most potent agonists (By similarity). In immune cells, functions as a pro-inflammatory receptor via 6-OAU and promotes the expression of pro-inflammatory mediators such as TNFalpha, IL-6 and IL-12B as well as stimulating chemotactic responses through activation of signaling mediators AKT, ERK and NF-kappa-B (By similarity). In addition, triggers increased bacterial adhesion and phagocytosis in macrophages and regulates pro-inflammatory function via enhancing NLRP3 inflammasome activation (By similarity). Also plays an important role in inflammation by modulating neutrophil functions (By similarity). Mechanistically, promotes neutrophil chemotaxis, reactive oxygen species (ROS) production and degranulation via LYN-AKT/ERK pathway (By similarity). To regulate ROS, communicates with the two formyl peptide receptors FPR2 and FPR1 to control the NADPH oxidase activity in neutrophils (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "A5D964", "ec_number_list": "", "go_molecular_function": "GO:0001604 urotensin II receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007218 neuropeptide signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q2KI97-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KIA2-1", "uniprot_id": "TR112_BOVIN", "mass": 14320.0, "length": 125, "protein_name": "Multifunctional methyltransferase subunit TRM112-like protein", "gene_name": "TRMT112", "organism": "Bovine", "refseq_name": "multifunctional methyltransferase subunit TRM112-like protein", "refseq_ac": "NP_001039446", "gene_names_uniprotkb": "TRMT112", "gene_names_refseq": "TRM112L; TRMT112; UPF0315", "protein_names_uniprotkb": "Multifunctional methyltransferase subunit TRM112-like protein; tRNA methyltransferase 112 homolog", "protein_names_refseq": "TRM112-like protein; multifunctional methyltransferase subunit TRM112-like protein; tRNA methyltransferase 11-2 homolog; tRNA methyltransferase 112 homolog; tRNA methyltransferase subunit 11-2", "tax_id": 9913, "disease": "", "pathway": " (bta:507833); (R-BTA-156581); (R-BTA-72764)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Acts as an activator of both rRNA/tRNA and protein methyltransferases. Together with methyltransferase BUD23, methylates the N(7) position of a guanine in 18S rRNA. The heterodimer with HEMK2/N6AMT1 catalyzes N5-methylation of ETF1 on 'Gln-185', using S-adenosyl L-methionine as methyl donor. The heterodimer with ALKBH8 catalyzes the methylation of 5-carboxymethyl uridine to 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in target tRNA species. Together with methyltransferase THUMPD3, catalyzes the formation of N(2)-methylguanosine at position 6 in a broad range of tRNA substrates and at position 7 of tRNA(Trp) (By similarity). Involved in the pre-rRNA processing steps leading to small-subunit rRNA production. Together with methyltransferase METTL5, specifically methylates the 6th position of adenine in position 1832 of 18S rRNA., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0046982 protein heterodimerization activity;GO:0141106 tRNA methyltransferase activator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0048471 perinuclear region of cytoplasm;GO:0043528 tRNA (m2G10) methyltransferase complex", "go_biological_process": "GO:0031167 rRNA methylation;GO:0070476 rRNA (guanine-N7)-methylation;GO:2000234 positive regulation of rRNA processing;GO:0045815 transcription initiation-coupled chromatin remodeling;GO:0030490 maturation of SSU-rRNA", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2KIA2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KIA6-1", "uniprot_id": "PRPF3_BOVIN", "mass": 77447.0, "length": 683, "protein_name": "U4/U6 small nuclear ribonucleoprotein Prp3", "gene_name": "PRPF3", "organism": "Bovine", "refseq_name": "U4/U6 small nuclear ribonucleoprotein Prp3", "refseq_ac": "NP_001039516", "gene_names_uniprotkb": "PRPF3", "gene_names_refseq": "PRPF3", "protein_names_uniprotkb": "U4/U6 small nuclear ribonucleoprotein Prp3; Pre-mRNA-splicing factor 3", "protein_names_refseq": "PRP3 pre-mRNA processing factor 3 homolog; U4/U6 small nuclear ribonucleoprotein Prp3; pre-mRNA-splicing factor 3", "tax_id": 9913, "disease": "", "pathway": " (bta:510322)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Plays a role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0016607 nuclear speck;GO:0005681 spliceosomal complex;GO:0046540 U4/U6 x U5 tri-snRNP complex", "go_biological_process": "GO:0000244 spliceosomal tri-snRNP complex assembly;GO:0000398 mRNA splicing, via spliceosome", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2KIA6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KIB0-1", "uniprot_id": "FAH2B_BOVIN", "mass": 34556.0, "length": 314, "protein_name": "Oxaloacetate tautomerase FAHD2B, mitochondrial", "gene_name": "FAHD2B", "organism": "Bovine", "refseq_name": "fumarylacetoacetate hydrolase domain-containing protein 2", "refseq_ac": "NP_991359", "gene_names_uniprotkb": "FAHD2B", "gene_names_refseq": "FAHD2A; FAHD2B; FAHD2; OAT1-A; OAT1-B", "protein_names_uniprotkb": "Oxaloacetate tautomerase FAHD2B, mitochondrial; 5.3.2.2; Fumarylacetoacetate hydrolase domain-containing protein 2B; OAT1-B; Oxaloacetate tautomerase 1-B", "protein_names_refseq": "fumarylacetoacetate hydrolase domain-containing protein 2A; fumarylacetoacetate hydrolase domain-containing protein 2B; fumarylacetoacetate hydrolase domain-containing protein 2; oxaloacetate tautomerase 1-A; oxaloacetate tautomerase 1-B", "tax_id": 9913, "disease": "", "pathway": " (bta:404123)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "38287013", "class_list": "", "function": "Tautomerase that converts enol-oxaloacetate, a strong inhibitor of succinate dehydrogenase, to the physiological keto form of oxaloacetate (PubMed:38287013). It is thereby required to maximize aerobic respiration efficiency by preventing succinate dehydrogenase inhibition (PubMed:38287013)., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q6Y1E3", "ec_number_list": "5.3.2.2;3.7.1.5;4.1.1.112", "go_molecular_function": "GO:0046872 metal ion binding;GO:0050163 oxaloacetate tautomerase activity", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0006107 oxaloacetate metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q2KIB0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KIB9-1", "uniprot_id": "RPP29_BOVIN", "mass": 25524.0, "length": 220, "protein_name": "Ribonuclease P protein subunit p29", "gene_name": "POP4", "organism": "Bovine", "refseq_name": "ribonuclease P protein subunit p29 isoform 1", "refseq_ac": "NP_001106753", "gene_names_uniprotkb": "POP4; RPP29", "gene_names_refseq": "POP4", "protein_names_uniprotkb": "Ribonuclease P protein subunit p29", "protein_names_refseq": "POP4 (processing of precursor, S. cerevisiae) homolog; processing of precursor 4, ribonuclease P/MRP subunit; ribonuclease P protein subunit p29 isoform 1; ribonuclease P protein subunit p29", "tax_id": 9913, "disease": "", "pathway": " (bta:614870)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0033204 ribonuclease P RNA binding", "go_cellular_component": "GO:0030681 multimeric ribonuclease P complex;GO:0005730 nucleolus;GO:0000172 ribonuclease MRP complex;GO:0030677 ribonuclease P complex;GO:0005634 nucleus", "go_biological_process": "GO:0006364 rRNA processing;GO:0001682 tRNA 5'-leader removal", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2KIB9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KIC0-1", "uniprot_id": "NSRP1_BOVIN", "mass": 66431.0, "length": 559, "protein_name": "Nuclear speckle splicing regulatory protein 1", "gene_name": "NSRP1", "organism": "Bovine", "refseq_name": "nuclear speckle splicing regulatory protein 1", "refseq_ac": "NP_001039927", "gene_names_uniprotkb": "NSRP1; CCDC55; NSRP70", "gene_names_refseq": "CCDC55; NSRP1; NSrp70", "protein_names_uniprotkb": "Nuclear speckle splicing regulatory protein 1; Coiled-coil domain-containing protein 55; NSrp70; Nuclear speckle-related protein 70", "protein_names_refseq": "coiled-coil domain containing 55; coiled-coil domain-containing protein 55; nuclear speckle splicing regulatory protein 1; nuclear speckle-related protein 70", "tax_id": 9913, "disease": "", "pathway": " (bta:539841); (R-BTA-72163)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "RNA-binding protein that mediates pre-mRNA alternative splicing regulation (By similarity). Through CCDC118 regulation, may promote pre-adipocyte differentiation (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 7, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003729 mRNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0016607 nuclear speck;GO:1990904 ribonucleoprotein complex", "go_biological_process": "GO:1904179 positive regulation of adipose tissue development;GO:0006397 mRNA processing;GO:0032502 developmental process;GO:0008380 RNA splicing;GO:0043484 regulation of RNA splicing", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2KIC0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KIC8-1", "uniprot_id": "TM100_BOVIN", "mass": 14341.0, "length": 134, "protein_name": "Transmembrane protein 100", "gene_name": "TMEM100", "organism": "Bovine", "refseq_name": "transmembrane protein 100", "refseq_ac": "NP_001039987", "gene_names_uniprotkb": "TMEM100", "gene_names_refseq": "TMEM100", "protein_names_uniprotkb": "Transmembrane protein 100", "protein_names_refseq": "transmembrane protein 100", "tax_id": 9913, "disease": "", "pathway": " (bta:613987)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Plays a role during embryonic arterial endothelium differentiation and vascular morphogenesis through the ACVRL1 receptor-dependent signaling pathway upon stimulation by bone morphogenetic proteins, such as GDF2/BMP9 and BMP10. Involved in the regulation of nociception, acting as a modulator of the interaction between TRPA1 and TRPV1, two molecular sensors and mediators of pain signals in dorsal root ganglia (DRG) neurons. Mechanistically, it weakens their interaction, thereby releasing the inhibition of TRPA1 by TRPV1 and increasing the single-channel open probability of the TRPA1-TRPV1 complex., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005886 plasma membrane;GO:0043204 perikaryon;GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "GO:0030154 cell differentiation;GO:0051930 regulation of sensory perception of pain;GO:0030509 BMP signaling pathway;GO:0045603 positive regulation of endothelial cell differentiation;GO:2001214 positive regulation of vasculogenesis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2KIC8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KIF1-1", "uniprot_id": "GATC_BOVIN", "mass": 15176.0, "length": 136, "protein_name": "Glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial", "gene_name": "GATC", "organism": "Bovine", "refseq_name": "glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial", "refseq_ac": "NP_001040027", "gene_names_uniprotkb": "GATC", "gene_names_refseq": "GATC", "protein_names_uniprotkb": "Glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial; 6.3.5.-; Glu-AdT subunit C", "protein_names_refseq": "GatC-like protein; glu-AdT subunit C; glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial; glutamyl-tRNA(Gln) amidotransferase, subunit C homolog", "tax_id": 9913, "disease": "", "pathway": " (bta:615845)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "6.3.5.7;6.3.5.-", "go_molecular_function": "GO:0005524 ATP binding;GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex", "go_biological_process": "GO:0032543 mitochondrial translation;GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation;GO:0006450 regulation of translational fidelity", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2KIF1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KIG2-1", "uniprot_id": "WDR5_BOVIN", "mass": 36516.0, "length": 334, "protein_name": "WD repeat-containing protein 5", "gene_name": "WDR5", "organism": "Bovine", "refseq_name": "WD repeat-containing protein 5", "refseq_ac": "NP_001098945", "gene_names_uniprotkb": "WDR5", "gene_names_refseq": "WDR5", "protein_names_uniprotkb": "WD repeat-containing protein 5", "protein_names_refseq": "WD repeat-containing protein 5", "tax_id": 9913, "disease": "", "pathway": " (bta:100125836)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Contributes to histone modification (By similarity). May position the N-terminus of histone H3 for efficient trimethylation at 'Lys-4' (By similarity). As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3 (By similarity). H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation (By similarity). As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues (By similarity). May regulate osteoblasts differentiation (By similarity). In association with RBBP5 and ASH2L, stimulates the histone methyltransferase activities of KMT2A, KMT2B, KMT2C, KMT2D, SETD1A and SETD1B (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0042393 histone binding;GO:0140109 histone H3K4me1 reader activity", "go_cellular_component": "GO:0005634 nucleus;GO:0035097 histone methyltransferase complex;GO:0048188 Set1C/COMPASS complex;GO:0071339 MLL1 complex;GO:0000123 histone acetyltransferase complex", "go_biological_process": "GO:0045815 transcription initiation-coupled chromatin remodeling", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2KIG2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KIH4-1", "uniprot_id": "RRS1_BOVIN", "mass": 41427.0, "length": 365, "protein_name": "Ribosome biogenesis regulatory protein homolog", "gene_name": "RRS1", "organism": "Bovine", "refseq_name": "ribosome biogenesis regulatory protein homolog", "refseq_ac": "NP_001068949", "gene_names_uniprotkb": "RRS1", "gene_names_refseq": "RRS1", "protein_names_uniprotkb": "Ribosome biogenesis regulatory protein homolog", "protein_names_refseq": "RRS1 ribosome biogenesis regulator homolog; ribosome biogenesis regulatory protein homolog", "tax_id": 9913, "disease": "", "pathway": " (bta:510956)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Involved in ribosomal large subunit assembly. May regulate the localization of the 5S RNP/5S ribonucleoprotein particle to the nucleolus., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008097 5S rRNA binding", "go_cellular_component": "GO:0000794 condensed nuclear chromosome;GO:0005730 nucleolus;GO:0030687 preribosome, large subunit precursor", "go_biological_process": "GO:1902570 protein localization to nucleolus;GO:0042273 ribosomal large subunit biogenesis;GO:1901796 regulation of signal transduction by p53 class mediator;GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0007080 mitotic metaphase chromosome alignment", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2KIH4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KII4-1", "uniprot_id": "ELOC_BOVIN", "mass": 12473.0, "length": 112, "protein_name": "Elongin-C", "gene_name": "ELOC", "organism": "Bovine", "refseq_name": "elongin-C", "refseq_ac": "NP_001039958", "gene_names_uniprotkb": "ELOC; TCEB1", "gene_names_refseq": "ELOC; TCEB1", "protein_names_uniprotkb": "Elongin-C; EloC; Elongin 15 kDa subunit; RNA polymerase II transcription factor SIII subunit C; SIII p15; Transcription elongation factor B polypeptide 1", "protein_names_refseq": "RNA polymerase II transcription factor SIII subunit C; SIII p15; elongin 15 kDa subunit; elongin-C; transcription elongation factor B polypeptide 1; transcription elongation factor B subunit 1", "tax_id": 9913, "disease": "", "pathway": " (bta:540859); (R-BTA-1234176); (R-BTA-674695); (R-BTA-6796648); (R-BTA-75955); (R-BTA-8951664); (R-BTA-9705462); (R-BTA-983168); (R-BTA-9954709)", "pathway_count": 9, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Core component of multiple cullin-RING-based ECS (ElonginB/C-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination of target proteins. By binding to BC-box motifs it seems to link target recruitment subunits, like VHL and members of the SOCS box family, to Cullin/RBX1 modules that activate E2 ubiquitination enzymes. Component the von Hippel-Lindau ubiquitination complex CBC(VHL). A number of ECS complexes (containing either KLHDC2, KLHDC3, KLHDC10, APPBP2, FEM1A, FEM1B or FEM1C as substrate-recognition component) are part of the DesCEND (destruction via C-end degrons) pathway, which recognizes a C-degron located at the extreme C terminus of target proteins, leading to their ubiquitination and degradation. The ECS(ASB9) complex mediates ubiquitination and degradation of CKB. As part of a multisubunit ubiquitin ligase complex, polyubiquitinates monoubiquitinated POLR2A (By similarity). ECS(LRR1) ubiquitinates MCM7 and promotes CMG replisome disassembly by VCP and chromatin extraction during S-phase (By similarity). As part of the ECS(RAB40C) complex, mediates ANKRD28 ubiquitination and degradation, thereby inhibiting protein phosphatase 6 (PP6) complex activity and focal adhesion assembly during cell migration (By similarity). The ECS(ASB7) complex acts a negative regulator of H3K9me3 histone mark by mediating ubiquitination and degradation of SUV39H1 (By similarity)., [UniProtKB, UniProtKB, UniProtKB]; SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A is transcriptionally active and its transcription activity is strongly enhanced by binding to the dimeric complex of the SIII regulatory subunits B and C (elongin BC complex) (By similarity). In embryonic stem cells, the elongin BC complex is recruited by EPOP to Polycomb group (PcG) target genes in order generate genomic region that display both active and repressive chromatin properties, an important feature of pluripotent stem cells (By similarity). As part of the ECS(LRRC58) complex, mediates CDO1 ubiquitination and degradation, regulating cysteine catabolism (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0030674 protein-macromolecule adaptor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0031466 Cul5-RING ubiquitin ligase complex;GO:0070449 elongin complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0016567 protein ubiquitination;GO:0006511 ubiquitin-dependent protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2KII4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KIJ6-1", "uniprot_id": "UBXN6_BOVIN", "mass": 49733.0, "length": 441, "protein_name": "UBX domain-containing protein 6", "gene_name": "UBXN6", "organism": "Bovine", "refseq_name": "UBX domain-containing protein 6", "refseq_ac": "NP_001039451", "gene_names_uniprotkb": "UBXN6; UBXD1", "gene_names_refseq": "UBXD1; UBXN6", "protein_names_uniprotkb": "UBX domain-containing protein 6; UBX domain-containing protein 1", "protein_names_refseq": "UBX domain containing 1; UBX domain-containing protein 1; UBX domain-containing protein 6", "tax_id": 9913, "disease": "", "pathway": " (bta:507936)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "May negatively regulate the ATPase activity of VCP, an ATP-driven segregase that associates with different cofactors to control a wide variety of cellular processes. As a cofactor of VCP, it may play a role in the transport of CAV1 to lysosomes for degradation. It may also play a role in endoplasmic reticulum-associated degradation (ERAD) of misfolded proteins. Together with VCP and other cofactors, it may play a role in macroautophagy, regulating for instance the clearance of damaged lysosomes., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005813 centrosome;GO:0005829 cytosol;GO:0016020 membrane", "go_biological_process": "GO:0016236 macroautophagy;GO:0036503 ERAD pathway;GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2KIJ6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KIN0-1", "uniprot_id": "ZCHC7_BOVIN", "mass": 63575.0, "length": 546, "protein_name": "Zinc finger CCHC domain-containing protein 7", "gene_name": "ZCCHC7", "organism": "Bovine", "refseq_name": "zinc finger CCHC domain-containing protein 7", "refseq_ac": "NP_001039565", "gene_names_uniprotkb": "ZCCHC7", "gene_names_refseq": "ZCCHC7", "protein_names_uniprotkb": "Zinc finger CCHC domain-containing protein 7; TRAMP-like complex RNA-binding factor ZCCHC7", "protein_names_refseq": "TRAMP-like complex RNA-binding factor ZCCHC7; zinc finger CCHC domain-containing protein 7; zinc finger, CCHC domain containing 7", "tax_id": 9913, "disease": "", "pathway": " (bta:511821)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005730 nucleolus;GO:0031499 TRAMP complex", "go_biological_process": "GO:0071035 nuclear polyadenylation-dependent rRNA catabolic process;GO:0071038 TRAMP-dependent tRNA surveillance pathway;GO:0071036 nuclear polyadenylation-dependent snoRNA catabolic process;GO:0071037 nuclear polyadenylation-dependent snRNA catabolic process;GO:0071039 nuclear polyadenylation-dependent CUT catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2KIN0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KIN4-1", "uniprot_id": "HEY1_BOVIN", "mass": 32572.0, "length": 304, "protein_name": "Hairy/enhancer-of-split related with YRPW motif protein 1", "gene_name": "HEY1", "organism": "Bovine", "refseq_name": "hairy/enhancer-of-split related with YRPW motif protein 1", "refseq_ac": "NP_001001172", "gene_names_uniprotkb": "HEY1", "gene_names_refseq": "CHF2; HEY1", "protein_names_uniprotkb": "Hairy/enhancer-of-split related with YRPW motif protein 1", "protein_names_refseq": "cardiovascular basic helix-loop-helix factor 2; hairy/enhancer-of-split related with YRPW motif 1; hairy/enhancer-of-split related with YRPW motif protein 1", "tax_id": 9913, "disease": "", "pathway": " (bta:408005)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Transcriptional repressor which binds preferentially to the canonical E box sequence 5'-CACGTG-3'. Downstream effector of Notch signaling required for cardiovascular development. Specifically required for the Notch-induced endocardial epithelial to mesenchymal transition, which is itself criticial for cardiac valve and septum development. May be required in conjunction with HEY2 to specify arterial cell fate or identity. Promotes maintenance of neuronal precursor cells and glial versus neuronal fate specification. Represses transcription by the cardiac transcriptional activators GATA4 and GATA6 and by the neuronal bHLH factors ASCL1/MASH1 and NEUROD4/MATH3., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0046983 protein dimerization activity;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0072359 circulatory system development;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0007219 Notch signaling pathway;GO:0045665 negative regulation of neuron differentiation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2KIN4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KIP7-1", "uniprot_id": "MD2L2_BOVIN", "mass": 24375.0, "length": 211, "protein_name": "Mitotic spindle assembly checkpoint protein MAD2B", "gene_name": "MAD2L2", "organism": "Bovine", "refseq_name": "mitotic spindle assembly checkpoint protein MAD2B", "refseq_ac": "NP_001039411", "gene_names_uniprotkb": "MAD2L2", "gene_names_refseq": "MAD2L2", "protein_names_uniprotkb": "Mitotic spindle assembly checkpoint protein MAD2B; MAD2-like protein 2; Mitotic arrest deficient 2-like protein 2", "protein_names_refseq": "MAD2 mitotic arrest deficient-like 2; MAD2-like protein 2; mitotic arrest deficient 2-like protein 2; mitotic spindle assembly checkpoint protein MAD2B", "tax_id": 9913, "disease": "", "pathway": " (bta:506605)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Adapter protein able to interact with different proteins and involved in different biological processes. Mediates the interaction between the error-prone DNA polymerase zeta catalytic subunit REV3L and the inserter polymerase REV1, thereby mediating the second polymerase switching in translesion DNA synthesis. Translesion DNA synthesis releases the replication blockade of replicative polymerases, stalled in presence of DNA lesions. Component of the shieldin complex, which plays an important role in repair of DNA double-stranded breaks (DSBs). During G1 and S phase of the cell cycle, the complex functions downstream of TP53BP1 to promote non-homologous end joining (NHEJ) and suppress DNA end resection. Mediates various NHEJ-dependent processes including immunoglobulin class-switch recombination, and fusion of unprotected telomeres. May also regulate another aspect of cellular response to DNA damage through regulation of the JNK-mediated phosphorylation and activation of the transcriptional activator ELK1. Inhibits the FZR1- and probably CDC20-mediated activation of the anaphase promoting complex APC thereby regulating progression through the cell cycle. Regulates TCF7L2-mediated gene transcription and may play a role in epithelial-mesenchymal transdifferentiation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008432 JUN kinase binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005819 spindle;GO:0016035 zeta DNA polymerase complex", "go_biological_process": "GO:0010717 regulation of epithelial to mesenchymal transition;GO:0006281 DNA repair;GO:0006351 DNA-templated transcription;GO:0033138 positive regulation of peptidyl-serine phosphorylation;GO:0051301 cell division", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2KIP7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KIQ4-1", "uniprot_id": "COQ2_BOVIN", "mass": 40628.0, "length": 371, "protein_name": "4-hydroxybenzoate polyprenyltransferase, mitochondrial", "gene_name": "COQ2", "organism": "Bovine", "refseq_name": "4-hydroxybenzoate polyprenyltransferase, mitochondrial precursor", "refseq_ac": "NP_001039358", "gene_names_uniprotkb": "COQ2", "gene_names_refseq": "COQ2; PHB:PPT", "protein_names_uniprotkb": "4-hydroxybenzoate polyprenyltransferase, mitochondrial; 2.5.1.39; 4-HB polyprenyltransferase; PHB:PPT; PHB:polyprenyltransferase; Para-hydroxybenzoate--polyprenyltransferase", "protein_names_refseq": "4-HB polyprenyltransferase; 4-hydroxybenzoate polyprenyltransferase, mitochondrial precursor; 4-hydroxybenzoate polyprenyltransferase, mitochondrial; PHB:polyprenyltransferase; coenzyme Q2 homolog, prenyltransferase; p-hydroxybenzoate polyprenyl transferase; para-hydroxybenzoate--polyprenyltransferase, mitochondrial", "tax_id": 9913, "disease": "", "pathway": " (bta:504633)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis. Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl donor (such as all-trans-decaprenyl diphosphate). The length of the polyprenyl side chain varies depending on the species, in humans, the side chain is comprised of 10 isoprenyls (decaprenyl) producing CoQ10 (also known as ubiquinone), whereas rodents predominantly generate CoQ9. However, this specificity is not complete, human tissues have low amounts of CoQ9 and rodent organs contain some CoQ10. Plays a central role in the biosynthesis of CoQ10. CoQ10 is a vital molecule that transports electrons from mitochondrial respiratory chain complexes. CoQs also function as cofactors for uncoupling protein and play a role as regulators of the extracellularly-induced ceramide-dependent apoptotic pathway (By similarity). Regulates mitochondrial permeability transition pore (mPTP) opening and ROS production (pivotal events in cell death) in a tissue specific manner (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.5.1.39", "go_molecular_function": "GO:0008412 4-hydroxybenzoate polyprenyltransferase activity", "go_cellular_component": "GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0006744 ubiquinone biosynthetic process;GO:0008299 isoprenoid biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2KIQ4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KIQ5-1", "uniprot_id": "T23O_BOVIN", "mass": 47708.0, "length": 406, "protein_name": "Tryptophan 2,3-dioxygenase", "gene_name": "TDO2", "organism": "Bovine", "refseq_name": "tryptophan 2,3-dioxygenase", "refseq_ac": "NP_001039778", "gene_names_uniprotkb": "TDO2", "gene_names_refseq": "TDO2; TRPO", "protein_names_uniprotkb": "Tryptophan 2,3-dioxygenase; 1.13.11.11; TDO; TO; TRPO; Tryptamin 2,3-dioxygenase; Tryptophan oxygenase; Tryptophan pyrrolase; Tryptophanase", "protein_names_refseq": "TDO; TO; tryptamin 2,3-dioxygenase; tryptophan 2,3-dioxygenase A; tryptophan 2,3-dioxygenase; tryptophan oxygenase; tryptophan pyrrolase; tryptophanase", "tax_id": 9913, "disease": "", "pathway": " (bta:530397); (R-BTA-71240)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.13.11.-;1.13.11.52;1.13.11.11", "go_molecular_function": "GO:0042802 identical protein binding;GO:0046872 metal ion binding;GO:0020037 heme binding;GO:0004833 L-tryptophan 2,3-dioxygenase activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0019441 L-tryptophan catabolic process to kynurenine;GO:0051289 protein homotetramerization;GO:0019442 L-tryptophan catabolic process to acetyl-CoA", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2KIQ5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KIR1-1", "uniprot_id": "SNRPA_BOVIN", "mass": 31264.0, "length": 282, "protein_name": "U1 small nuclear ribonucleoprotein A", "gene_name": "SNRPA", "organism": "Bovine", "refseq_name": "U1 small nuclear ribonucleoprotein A", "refseq_ac": "NP_001039504", "gene_names_uniprotkb": "SNRPA", "gene_names_refseq": "SNRPA; U1A", "protein_names_uniprotkb": "U1 small nuclear ribonucleoprotein A; U1 snRNP A; U1-A; U1A", "protein_names_refseq": "U1 small nuclear ribonucleoprotein A; U1 snRNP A; U1 snRNP protein A; U1-A", "tax_id": 9913, "disease": "", "pathway": " (bta:509802); (R-BTA-72163); (R-BTA-9770562)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1 snRNP is the first snRNP to interact with pre-mRNA. This interaction is required for the subsequent binding of U2 snRNP and the U4/U6/U5 tri-snRNP. SNRPA binds stem loop II of U1 snRNA. In a snRNP-free form (SF-A) may be involved in coupled pre-mRNA splicing and polyadenylation process. May bind preferentially to the 5'-UGCAC-3' motif on RNAs (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding;GO:0042802 identical protein binding;GO:0030619 U1 snRNA binding", "go_cellular_component": "GO:0005685 U1 snRNP;GO:0005654 nucleoplasm;GO:0005681 spliceosomal complex", "go_biological_process": "GO:0000398 mRNA splicing, via spliceosome", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2KIR1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KIR8-1", "uniprot_id": "TDH_BOVIN", "mass": 41846.0, "length": 373, "protein_name": "L-threonine 3-dehydrogenase, mitochondrial", "gene_name": "TDH", "organism": "Bovine", "refseq_name": "L-threonine 3-dehydrogenase, mitochondrial precursor", "refseq_ac": "NP_001039569", "gene_names_uniprotkb": "TDH", "gene_names_refseq": "TDH", "protein_names_uniprotkb": "L-threonine 3-dehydrogenase, mitochondrial; 1.1.1.103", "protein_names_refseq": "L-threonine 3-dehydrogenase, mitochondrial precursor; L-threonine 3-dehydrogenase, mitochondrial", "tax_id": 9913, "disease": "", "pathway": " (bta:511957)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate, mediating L-threonine catabolism., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.1.1.103", "go_molecular_function": "GO:0042802 identical protein binding;GO:0008743 L-threonine 3-dehydrogenase activity", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0019518 L-threonine catabolic process to glycine;GO:0006567 L-threonine catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2KIR8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KIT1-1", "uniprot_id": "PKRI1_BOVIN", "mass": 21262.0, "length": 186, "protein_name": "PRKR-interacting protein 1", "gene_name": "PRKRIP1", "organism": "Bovine", "refseq_name": "PRKR-interacting protein 1", "refseq_ac": "NP_001073109", "gene_names_uniprotkb": "PRKRIP1", "gene_names_refseq": "PRKRIP1", "protein_names_uniprotkb": "PRKR-interacting protein 1", "protein_names_refseq": "PRKR interacting protein 1 (IL11 inducible); PRKR-interacting protein 1", "tax_id": 9913, "disease": "", "pathway": " (bta:780786)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Required for pre-mRNA splicing as component of the spliceosome (By similarity). Binds double-stranded RNA. Inhibits EIF2AK2 kinase activity (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0019901 protein kinase binding;GO:0004860 protein kinase inhibitor activity;GO:0003725 double-stranded RNA binding", "go_cellular_component": "GO:0005730 nucleolus;GO:0005681 spliceosomal complex", "go_biological_process": "GO:0006397 mRNA processing;GO:0008380 RNA splicing", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2KIT1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KIU2-1", "uniprot_id": "PMVK_BOVIN", "mass": 21956.0, "length": 192, "protein_name": "Phosphomevalonate kinase", "gene_name": "PMVK", "organism": "Bovine", "refseq_name": "phosphomevalonate kinase", "refseq_ac": "NP_001039616", "gene_names_uniprotkb": "PMVK", "gene_names_refseq": "PMVK", "protein_names_uniprotkb": "Phosphomevalonate kinase; 2.7.4.2; PMKase", "protein_names_refseq": "PMKase; phosphomevalonate kinase", "tax_id": 9913, "disease": "", "pathway": " (bta:513533)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalyzes the reversible ATP-dependent phosphorylation of mevalonate 5-phosphate to produce mevalonate diphosphate and ADP, a key step in the mevalonic acid mediated biosynthesis of isopentenyl diphosphate and other polyisoprenoid metabolites., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.4.2", "go_molecular_function": "GO:0005524 ATP binding;GO:0004631 phosphomevalonate kinase activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0006695 cholesterol biosynthetic process;GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2KIU2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KIW5-1", "uniprot_id": "CENPU_BOVIN", "mass": 46674.0, "length": 408, "protein_name": "Centromere protein U", "gene_name": "CENPU", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "CENPU; MLF1IP", "gene_names_refseq": "", "protein_names_uniprotkb": "Centromere protein U; CENP-U; MLF1-interacting protein", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. Plays an important role in the correct PLK1 localization to the mitotic kinetochores. A scaffold protein responsible for the initial recruitment and maintenance of the kinetochore PLK1 population until its degradation. Involved in transcriptional repression (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 14, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0000776 kinetochore", "go_biological_process": "GO:0006351 DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2KIW5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KIW6-1", "uniprot_id": "PRS10_BOVIN", "mass": 44074.0, "length": 389, "protein_name": "26S proteasome regulatory subunit 10B", "gene_name": "PSMC6", "organism": "Bovine", "refseq_name": "26S proteasome regulatory subunit 10B", "refseq_ac": "NP_001039705", "gene_names_uniprotkb": "PSMC6", "gene_names_refseq": "PSMC6", "protein_names_uniprotkb": "26S proteasome regulatory subunit 10B; 26S proteasome AAA-ATPase subunit RPT4; Proteasome 26S subunit ATPase 6", "protein_names_refseq": "26S protease regulatory subunit 10B; 26S protease regulatory subunit S10B; 26S proteasome AAA-ATPase subunit RPT4; 26S proteasome regulatory subunit 10B; proteasome (prosome, macropain) 26S subunit, ATPase, 6; proteasome 26S ATPase subunit 6", "tax_id": 9913, "disease": "", "pathway": " (bta:518637)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "30573663", "class_list": "", "function": "Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC6 belongs to the heterohexameric ring of AAA (ATPases associated with diverse cellular activities) proteins that unfolds ubiquitinated target proteins that are concurrently translocated into a proteolytic chamber and degraded into peptides., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0036402 proteasome-activating activity", "go_cellular_component": "GO:0008540 proteasome regulatory particle, base subcomplex;GO:0022624 proteasome accessory complex;GO:0005634 nucleus;GO:0005829 cytosol", "go_biological_process": "GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0036503 ERAD pathway;GO:0045899 positive regulation of RNA polymerase II transcription preinitiation complex assembly", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q2KIW6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KIY3-1", "uniprot_id": "WDFY1_BOVIN", "mass": 46281.0, "length": 410, "protein_name": "WD repeat and FYVE domain-containing protein 1", "gene_name": "WDFY1", "organism": "Bovine", "refseq_name": "WD repeat and FYVE domain-containing protein 1", "refseq_ac": "NP_001040007", "gene_names_uniprotkb": "WDFY1", "gene_names_refseq": "WDFY1", "protein_names_uniprotkb": "WD repeat and FYVE domain-containing protein 1; WD40- and FYVE domain-containing protein 1", "protein_names_refseq": "WD repeat and FYVE domain-containing protein 1; WD40- and FYVE domain-containing protein 1", "tax_id": 9913, "disease": "", "pathway": " (bta:614729)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Positively regulates TLR3- and TLR4-mediated signaling pathways by bridging the interaction between TLR3 or TLR4 and TICAM1. Promotes TLR3/4 ligand-induced activation of transcription factors IRF3 and NF-kappa-B, as well as the production of IFN-beta and inflammatory cytokines., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0005545 1-phosphatidylinositol binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005769 early endosome;GO:0005829 cytosol", "go_biological_process": "GO:0034141 positive regulation of toll-like receptor 3 signaling pathway;GO:0034145 positive regulation of toll-like receptor 4 signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2KIY3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KIY5-1", "uniprot_id": "PLBL2_BOVIN", "mass": 65693.0, "length": 589, "protein_name": "Putative aminopeptidase PLBD2", "gene_name": "PLBD2", "organism": "Bovine", "refseq_name": "putative aminopeptidase PLBD2 precursor", "refseq_ac": "NP_001039635", "gene_names_uniprotkb": "PLBD2", "gene_names_refseq": "P76; PLBD2", "protein_names_uniprotkb": "Putative aminopeptidase PLBD2; 3.4.11.-; LAMA-like protein 2; Lamina ancestor homolog 2; Phospholipase B domain-containing protein 2", "protein_names_refseq": "LAMA-like protein 2; lamina ancestor homolog 2; mannose-6-phosphate protein p76; phospholipase B domain-containing protein 2; putative aminopeptidase PLBD2 precursor; putative aminopeptidase PLBD2; putative phospholipase B-like 2", "tax_id": 9913, "disease": "", "pathway": " (bta:514347)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Putative aminopeptidase., [UniProtKB, UniProtKB]", "predicted_glycosites": 8, "predicted_n_glycosites": 7, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 8, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004620 phospholipase activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0043202 lysosomal lumen", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2KIY5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KJ21-1", "uniprot_id": "CACO1_BOVIN", "mass": 75661.0, "length": 680, "protein_name": "Calcium-binding and coiled-coil domain-containing protein 1", "gene_name": "CALCOCO1", "organism": "Bovine", "refseq_name": "calcium-binding and coiled-coil domain-containing protein 1", "refseq_ac": "NP_001039900", "gene_names_uniprotkb": "CALCOCO1", "gene_names_refseq": "CALCOCO1", "protein_names_uniprotkb": "Calcium-binding and coiled-coil domain-containing protein 1", "protein_names_refseq": "calcium-binding and coiled-coil domain-containing protein 1", "tax_id": 9913, "disease": "", "pathway": " (bta:538675)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Functions as a coactivator for aryl hydrocarbon and nuclear receptors (NR). Recruited to promoters through its contact with the N-terminal basic helix-loop-helix-Per-Arnt-Sim (PAS) domain of transcription factors or coactivators, such as NCOA2. During ER-activation acts synergistically in combination with other NCOA2-binding proteins, such as EP300, CREBBP and CARM1. Involved in the transcriptional activation of target genes in the Wnt/CTNNB1 pathway. Functions as a secondary coactivator in LEF1-mediated transcriptional activation via its interaction with CTNNB1. Coactivator function for nuclear receptors and LEF1/CTNNB1 involves differential utilization of two different activation regions. In association with CCAR1 enhances GATA1- and MED1-mediated transcriptional activation from the gamma-globin promoter during erythroid differentiation of K562 erythroleukemia cells (By similarity)., [UniProtKB, UniProtKB]; Seems to enhance inorganic pyrophosphatase thus activating phosphogluomutase (PMG). Probably functions as a component of the calphoglin complex, which is involved in linking cellular metabolism (phosphate and glucose metabolism) with other core functions including protein synthesis and degradation, calcium signaling and cell growth (By similarity)., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003713 transcription coactivator activity;GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0016055 Wnt signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2KJ21-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KJ22-1", "uniprot_id": "MINY1_BOVIN", "mass": 51289.0, "length": 469, "protein_name": "Ubiquitin carboxyl-terminal hydrolase MINDY-1", "gene_name": "MINDY1", "organism": "Bovine", "refseq_name": "ubiquitin carboxyl-terminal hydrolase MINDY-1", "refseq_ac": "NP_001039389", "gene_names_uniprotkb": "MINDY1; FAM63A", "gene_names_refseq": "FAM63A; MINDY1", "protein_names_uniprotkb": "Ubiquitin carboxyl-terminal hydrolase MINDY-1; 3.4.19.12; Deubiquitinating enzyme MINDY-1; Protein FAM63A", "protein_names_refseq": "deubiquitinating enzyme MINDY-1; family with sequence similarity 63 member A; protein FAM63A; ubiquitin carboxyl-terminal hydrolase MINDY-1", "tax_id": 9913, "disease": "", "pathway": " (bta:505719)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Hydrolase that can specifically remove 'Lys-48'-linked conjugated ubiquitin from proteins. Has exodeubiquitinase activity and has a preference for long polyubiquitin chains. May play a regulatory role at the level of protein turnover., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0036435 K48-linked polyubiquitin modification-dependent protein binding;GO:0016807 cysteine-type carboxypeptidase activity;GO:0004843 cysteine-type deubiquitinase activity;GO:1990380 K48-linked deubiquitinase activity", "go_cellular_component": "GO:0005654 nucleoplasm", "go_biological_process": "GO:0006508 proteolysis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2KJ22-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KJ28-1", "uniprot_id": "PGPS1_BOVIN", "mass": 62732.0, "length": 556, "protein_name": "CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial", "gene_name": "PGS1", "organism": "Bovine", "refseq_name": "CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial precursor", "refseq_ac": "NP_001039860", "gene_names_uniprotkb": "PGS1", "gene_names_refseq": "PGS1", "protein_names_uniprotkb": "CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial; 2.7.8.5; PGP synthase 1; Phosphatidylglycerophosphate synthase 1", "protein_names_refseq": "CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial precursor; CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial; PGP synthase 1", "tax_id": 9913, "disease": "", "pathway": " (bta:535126)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.8.5", "go_molecular_function": "GO:0005524 ATP binding;GO:0008444 CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0032049 cardiolipin biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2KJ28-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KJ34-1", "uniprot_id": "HBP1_BOVIN", "mass": 57383.0, "length": 512, "protein_name": "HMG box-containing protein 1", "gene_name": "HBP1", "organism": "Bovine", "refseq_name": "HMG box-containing protein 1 isoform X2", "refseq_ac": "XP_059741546", "gene_names_uniprotkb": "HBP1", "gene_names_refseq": "HBP1", "protein_names_uniprotkb": "HMG box-containing protein 1; HMG box transcription factor 1; High mobility group box transcription factor 1", "protein_names_refseq": "HMG box-containing protein 1 isoform X2", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the histone H1.0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4 (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0016055 Wnt signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2KJ34-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KJ46-1", "uniprot_id": "PSMD3_BOVIN", "mass": 60957.0, "length": 534, "protein_name": "26S proteasome non-ATPase regulatory subunit 3", "gene_name": "PSMD3", "organism": "Bovine", "refseq_name": "26S proteasome non-ATPase regulatory subunit 3", "refseq_ac": "NP_001039365", "gene_names_uniprotkb": "PSMD3", "gene_names_refseq": "PSMD3", "protein_names_uniprotkb": "26S proteasome non-ATPase regulatory subunit 3; 26S proteasome regulatory subunit RPN3", "protein_names_refseq": "26S proteasome non-ATPase regulatory subunit 3; 26S proteasome regulatory subunit RPN3; proteasome (prosome, macropain) 26S subunit, non-ATPase, 3", "tax_id": 9913, "disease": "", "pathway": " (bta:504937); (R-BTA-1169091); (R-BTA-1234176); (R-BTA-1236978); (R-BTA-174084); (R-BTA-174154); (R-BTA-174178); (R-BTA-174184); (R-BTA-187577); (R-BTA-195253); (R-BTA-202424); (R-BTA-2467813); (R-BTA-2871837); (R-BTA-349425); (R-BTA-350562); (R-BTA-382556); (R-BTA-450408); (R-BTA-4608870); (R-BTA-4641257); (R-BTA-4641258); (R-BTA-5358346); (R-BTA-5607761); (R-BTA-5607764); (R-BTA-5610780); (R-BTA-5610785); (R-BTA-5632684); (R-BTA-5668541); (R-BTA-5676590); (R-BTA-5687128); (R-BTA-5689603); (R-BTA-5689880); (R-BTA-6798695); (R-BTA-68867); (R-BTA-68949); (R-BTA-69017); (R-BTA-69481); (R-BTA-69601); (R-BTA-75815); (R-BTA-8852276); (R-BTA-8854050); (R-BTA-8939236); (R-BTA-8939902); (R-BTA-8941858); (R-BTA-8948751); (R-BTA-8951664); (R-BTA-9020702); (R-BTA-9755511); (R-BTA-9762114); (R-BTA-9766229); (R-BTA-983168); (R-BTA-9907900); (R-BTA-9929356); (R-BTA-9929491); (R-BTA-9931269); (R-BTA-9932298); (R-BTA-9954709)", "pathway_count": 56, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0030234 enzyme regulator activity", "go_cellular_component": "GO:0022624 proteasome accessory complex;GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0008541 proteasome regulatory particle, lid subcomplex", "go_biological_process": "GO:0006511 ubiquitin-dependent protein catabolic process;GO:0042176 regulation of protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2KJ46-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KJ64-1", "uniprot_id": "ARGI1_BOVIN", "mass": 35009.0, "length": 322, "protein_name": "Arginase-1", "gene_name": "ARG1", "organism": "Bovine", "refseq_name": "arginase-1", "refseq_ac": "NP_001039619", "gene_names_uniprotkb": "ARG1", "gene_names_refseq": "ARG1", "protein_names_uniprotkb": "Arginase-1; 3.5.3.1; Liver-type arginase; Type I arginase", "protein_names_refseq": "arginase I; arginase, liver; arginase-1; liver-type arginase; type I arginase", "tax_id": 9913, "disease": "", "pathway": " (bta:513608); (R-BTA-6798695); (R-BTA-70635)", "pathway_count": 3, "publication_count": 5, "publication_id_list": "15994432;17967788;25445030;25446432;28583613", "class_list": "", "function": "Activity of arginase before and at the time of parturition might be a potential marker for occurrence of metritis, especially in cows that develop retained fetal membranes., [RefSeq, PubMed]; Ang II increases endothelial arginase activity/expression through a p38 MAPK/ATF-2 pathway leading to reduced endothelial NO production, [RefSeq, PubMed]; Arginase has a role in preventing angiogenesis in endothelial cells exposed to hypoxia, [RefSeq, PubMed]; High glucose (HG)-treated bovine coronary endothelial cells (BCECs) showed increased arginase activity and diminished NO production, [RefSeq, PubMed]; Results indicate that arginase induction depends in part on epidermal growth factor (EGF) receptor activity, and that EGFR inhibitors may attenuate vascular remodeling without affecting nitric oxide release, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "5.3.4.1;3.2.1.23;3.6.1.6;3.1.3.16;3.1.6.4;3.1.6.14;1.1.1.205;3.2.1.18;3.4.19.9;3.2.1.-;3.5.3.1;3.5.3.17;3.5.3.7;2.7.10.2;3.5.1.26;3.5.1.3;3.4.23.5;2.4.1.1;1.6.5.5;3.5.4.4;3.2.1.166;3.2.1.51;3.1.3.48;3.6.4.6;3.2.1.52;1.11.1.27;3.1.1.4;2.3.1.23;3.4.18.1;1.6.2.2;3.4.21.-;2.7.11.24;3.2.1.17;3.1.6.8;2.7.1.35;3.2.1.24;2.3.3.8;3.4.16.5;3.4.16.-;3.6.1.-", "go_molecular_function": "GO:0030145 manganese ion binding;GO:0004053 arginase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0042127 regulation of cell population proliferation;GO:0000050 urea cycle;GO:0006525 arginine metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q2KJ64-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KJA4-1", "uniprot_id": "OBF1_BOVIN", "mass": 27436.0, "length": 256, "protein_name": "POU domain class 2-associating factor 1", "gene_name": "POU2AF1", "organism": "Bovine", "refseq_name": "POU domain class 2-associating factor 1", "refseq_ac": "NP_001069383", "gene_names_uniprotkb": "POU2AF1; OBF1", "gene_names_refseq": "BOB-1; POU2AF1", "protein_names_uniprotkb": "POU domain class 2-associating factor 1; B-cell-specific coactivator OBF-1; OCT-binding factor 1", "protein_names_refseq": "B-cell-specific coactivator OBF-1; OCT binding factor 1; POU class 2 associating factor 1; POU domain class 2-associating factor 1; POU domain, class 2, associating factor 1", "tax_id": 9913, "disease": "", "pathway": " (bta:528475)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Transcriptional coactivator that specifically associates with either POU2F1/OCT1 or POU2F2/OCT2. It boosts the POU2F1/OCT1 mediated promoter activity and to a lesser extent, that of POU2F2/OCT2. It recognizes the POU domains of POU2F1/OCT1 and POU2F2/OCT2. It is essential for the response of B-cells to antigens and required for the formation of germinal centers. Regulates IL6 expression in B cells as POU2F2/OCT2 coactivator., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0003713 transcription coactivator activity;GO:0070974 POU domain binding", "go_cellular_component": "GO:0090575 RNA polymerase II transcription regulator complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0032755 positive regulation of interleukin-6 production;GO:0002314 germinal center B cell differentiation;GO:0098586 cellular response to virus", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2KJA4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KJA5-1", "uniprot_id": "LAPM5_BOVIN", "mass": 29880.0, "length": 264, "protein_name": "Lysosomal-associated transmembrane protein 5", "gene_name": "LAPTM5", "organism": "Bovine", "refseq_name": "lysosomal-associated transmembrane protein 5", "refseq_ac": "NP_001039583", "gene_names_uniprotkb": "LAPTM5", "gene_names_refseq": "HA1520; LAPTM5", "protein_names_uniprotkb": "Lysosomal-associated transmembrane protein 5; Lysosomal-associated multitransmembrane protein 5", "protein_names_refseq": "lysosomal associated multispanning membrane protein 5; lysosomal multispanning membrane protein 5; lysosomal-associated multitransmembrane protein 5; lysosomal-associated transmembrane protein 5; retinoic acid-inducible E3 protein", "tax_id": 9913, "disease": "", "pathway": " (bta:512361)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "May have a special functional role during embryogenesis and in adult hematopoietic cells., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0140311 protein sequestering activity", "go_cellular_component": "GO:0005765 lysosomal membrane", "go_biological_process": "GO:0097213 regulation of lysosomal membrane permeability", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2KJA5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KJB5-1", "uniprot_id": "NOSTN_BOVIN", "mass": 57307.0, "length": 505, "protein_name": "Nostrin", "gene_name": "NOSTRIN", "organism": "Bovine", "refseq_name": "nostrin", "refseq_ac": "NP_001039722", "gene_names_uniprotkb": "NOSTRIN", "gene_names_refseq": "NOSTRIN", "protein_names_uniprotkb": "Nostrin; Nitric oxide synthase trafficker; eNOS trafficking inducer", "protein_names_refseq": "eNOS trafficking inducer; nitric oxide synthase trafficker; nostrin", "tax_id": 9913, "disease": "", "pathway": " (bta:521834)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "17071725", "class_list": "", "function": "Multivalent adapter protein which may decrease NOS3 activity by inducing its translocation away from the plasma membrane., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0030674 protein-macromolecule adaptor activity", "go_cellular_component": "GO:0005856 cytoskeleton;GO:0005886 plasma membrane;GO:0031410 cytoplasmic vesicle", "go_biological_process": "GO:0006897 endocytosis;GO:0007165 signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q2KJB5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KJD3-1", "uniprot_id": "CWC15_BOVIN", "mass": 26869.0, "length": 231, "protein_name": "Spliceosome-associated protein CWC15 homolog", "gene_name": "CWC15", "organism": "Bovine", "refseq_name": "spliceosome-associated protein CWC15 homolog", "refseq_ac": "NP_001039864", "gene_names_uniprotkb": "CWC15", "gene_names_refseq": "CWC15", "protein_names_uniprotkb": "Spliceosome-associated protein CWC15 homolog", "protein_names_refseq": "protein CWC15 homolog; spliceosome-associated protein CWC15 homolog", "tax_id": 9913, "disease": "", "pathway": " (bta:535258); (R-BTA-72163)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "23349982", "class_list": "", "function": "By combining SNP analysis of whole-genome sequences aligned to the JH1 interval and subsequent SNP validation a nonsense mutation in CWC15 was identified as the likely causative mutation underlying the fertility phenotype, [RefSeq, PubMed]; Involved in pre-mRNA splicing as component of the spliceosome. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0016607 nuclear speck;GO:0005681 spliceosomal complex;GO:0071013 catalytic step 2 spliceosome;GO:0071007 U2-type catalytic step 2 spliceosome", "go_biological_process": "GO:0000398 mRNA splicing, via spliceosome;GO:0045292 mRNA cis splicing, via spliceosome", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q2KJD3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KJD7-1", "uniprot_id": "UBCP1_BOVIN", "mass": 36805.0, "length": 318, "protein_name": "Ubiquitin-like domain-containing CTD phosphatase 1", "gene_name": "UBLCP1", "organism": "Bovine", "refseq_name": "ubiquitin-like domain-containing CTD phosphatase 1", "refseq_ac": "NP_001039459", "gene_names_uniprotkb": "UBLCP1", "gene_names_refseq": "UBLCP1", "protein_names_uniprotkb": "Ubiquitin-like domain-containing CTD phosphatase 1; 3.1.3.16; Nuclear proteasome inhibitor UBLCP1", "protein_names_refseq": "nuclear proteasome inhibitor UBLCP1; ubiquitin-like domain-containing CTD phosphatase 1", "tax_id": 9913, "disease": "", "pathway": " (bta:508163)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Dephosphorylates 26S nuclear proteasomes, thereby decreasing their proteolytic activity. Recruited to the 19S regulatory particle of the 26S proteasome through its interaction with 19S component PSMD2/RPN1. Once recruited, dephosphorylates 19S component PSMC2/RPT1 which impairs PSMC2 ATPase activity and disrupts 26S proteasome assembly. Has also been reported to stimulate the proteolytic activity of the 26S proteasome., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.1.3.16;3.1.3.48;3.1.3.67;3.1.3.74;3.1.3.52;3.1.3.53", "go_molecular_function": "GO:0046872 metal ion binding;GO:0004722 protein serine/threonine phosphatase activity;GO:1904855 proteasome regulatory particle binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005730 nucleolus", "go_biological_process": "GO:0090364 regulation of proteasome assembly", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2KJD7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KJD8-1", "uniprot_id": "CDN2B_BOVIN", "mass": 14028.0, "length": 131, "protein_name": "Cyclin-dependent kinase 4 inhibitor B", "gene_name": "CDKN2B", "organism": "Bovine", "refseq_name": "cyclin-dependent kinase 4 inhibitor B", "refseq_ac": "NP_001069362", "gene_names_uniprotkb": "CDKN2B", "gene_names_refseq": "CDKN2B; MTS2", "protein_names_uniprotkb": "Cyclin-dependent kinase 4 inhibitor B; p14-INK4b", "protein_names_refseq": "cyclin-dependent kinase 4 inhibitor B; p14-INK4b", "tax_id": 9913, "disease": "", "pathway": " (bta:527124)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Interacts strongly with CDK4 and CDK6. Potent inhibitor. Potential effector of TGF-beta induced cell cycle arrest (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0019901 protein kinase binding;GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0030219 megakaryocyte differentiation;GO:0031670 cellular response to nutrient;GO:0008285 negative regulation of cell population proliferation;GO:0050680 negative regulation of epithelial cell proliferation;GO:0007179 transforming growth factor beta receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2KJD8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KJE4-1", "uniprot_id": "ETFA_BOVIN", "mass": 34957.0, "length": 333, "protein_name": "Electron transfer flavoprotein subunit alpha, mitochondrial", "gene_name": "ETFA", "organism": "Bovine", "refseq_name": "electron transfer flavoprotein subunit alpha, mitochondrial", "refseq_ac": "NP_001069290", "gene_names_uniprotkb": "ETFA", "gene_names_refseq": "ETFA", "protein_names_uniprotkb": "Electron transfer flavoprotein subunit alpha, mitochondrial; Alpha-ETF", "protein_names_refseq": "alpha-ETF; electron transfer flavoprotein alpha subunit; electron transfer flavoprotein alpha-subunit, mitochondrial; electron transfer flavoprotein subunit alpha, mitochondrial; electron-transfer-flavoprotein, alpha polypeptide (glutaric aciduria II); glutaric aciduria II", "tax_id": 9913, "disease": "", "pathway": " (bta:521892)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Heterodimeric electron transfer flavoprotein that accepts electrons from several mitochondrial dehydrogenases, including acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase). Required for normal mitochondrial fatty acid oxidation and normal amino acid metabolism., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "F1MWR3", "ec_number_list": "", "go_molecular_function": "GO:0009055 electron transfer activity;GO:0050660 flavin adenine dinucleotide binding", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix;GO:0045251 electron transfer flavoprotein complex", "go_biological_process": "GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2KJE4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KJE5-1", "uniprot_id": "G3PT_BOVIN", "mass": 43288.0, "length": 395, "protein_name": "Glyceraldehyde-3-phosphate dehydrogenase, testis-specific", "gene_name": "GAPDHS", "organism": "Bovine", "refseq_name": "glyceraldehyde-3-phosphate dehydrogenase, testis-specific", "refseq_ac": "NP_001035642", "gene_names_uniprotkb": "GAPDHS", "gene_names_refseq": "GAPDHS", "protein_names_uniprotkb": "Glyceraldehyde-3-phosphate dehydrogenase, testis-specific; 1.2.1.12; Spermatogenic glyceraldehyde-3-phosphate dehydrogenase", "protein_names_refseq": "glyceraldehyde-3-phosphate dehydrogenase, testis-specific; spermatogenic glyceraldehyde-3-phosphate dehydrogenase", "tax_id": 9913, "disease": "", "pathway": " (bta:532231); (R-BTA-70171); (R-BTA-70263)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "36672976", "class_list": "", "function": "Catalyzes the conversion of D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate in glycolysis and the reverse reaction in gluconeogenesis (By similarity). May play an important role in regulating the switch between different pathways for energy production during spermiogenesis and in the spermatozoon. Required for sperm motility and male fertility (By similarity)., [UniProtKB, UniProtKB, UniProtKB]; Sorted Bulls' X-Chromosome-Bearing Spermatozoa Show Increased GAPDHS Activity Correlating with Motility. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.2.1.12;2.6.99.-", "go_molecular_function": "GO:0051287 NAD binding;GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity;GO:0050661 NADP binding", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0006006 glucose metabolic process;GO:0006096 glycolytic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q2KJE5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KJG1-1", "uniprot_id": "SPAT6_BOVIN", "mass": 56137.0, "length": 487, "protein_name": "Spermatogenesis-associated protein 6", "gene_name": "SPATA6", "organism": "Bovine", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "SPATA6", "gene_names_refseq": "", "protein_names_uniprotkb": "Spermatogenesis-associated protein 6", "protein_names_refseq": "", "tax_id": 9913, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Required for formation of the sperm connecting piece during spermiogenesis. Sperm connecting piece is essential for linking the developing flagellum to the head during late spermiogenesis. May be involved in myosin-based microfilament transport through interaction with myosin subunits., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 11, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0032027 myosin light chain binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0031514 motile cilium;GO:0120212 sperm head-tail coupling apparatus", "go_biological_process": "GO:0007283 spermatogenesis;GO:0030154 cell differentiation;GO:0044458 motile cilium assembly", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2KJG1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KJG2-1", "uniprot_id": "UFM1_BOVIN", "mass": 9168.0, "length": 85, "protein_name": "Ubiquitin-fold modifier 1", "gene_name": "UFM1", "organism": "Bovine", "refseq_name": "ubiquitin-fold modifier 1", "refseq_ac": "NP_001039779", "gene_names_uniprotkb": "UFM1", "gene_names_refseq": "UFM1", "protein_names_uniprotkb": "Ubiquitin-fold modifier 1", "protein_names_refseq": "ubiquitin-fold modifier 1", "tax_id": 9913, "disease": "", "pathway": " (bta:530547)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Ubiquitin-like modifier which can be covalently attached via an isopeptide bond to lysine residues of substrate proteins as a monomer or a lysine-linked polymer. The so-called ufmylation, requires the UFM1-activating E1 enzyme UBA5, the UFM1-conjugating E2 enzyme UFC1, and the UFM1-ligase E3 enzyme UFL1. Ufmylation is involved in various processes, such as ribosome recycling, response to DNA damage, transcription or reticulophagy (also called ER-phagy) induced in response to endoplasmic reticulum stress., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0007420 brain development;GO:0034976 response to endoplasmic reticulum stress;GO:0071569 protein ufmylation;GO:0061709 reticulophagy;GO:1990592 protein K69-linked ufmylation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2KJG2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KJH4-1", "uniprot_id": "WDR1_BOVIN", "mass": 66258.0, "length": 606, "protein_name": "WD repeat-containing protein 1", "gene_name": "WDR1", "organism": "Bovine", "refseq_name": "WD repeat-containing protein 1", "refseq_ac": "NP_001039811", "gene_names_uniprotkb": "WDR1", "gene_names_refseq": "WDR1", "protein_names_uniprotkb": "WD repeat-containing protein 1", "protein_names_refseq": "WD repeat-containing protein 1", "tax_id": 9913, "disease": "", "pathway": " (bta:533223)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Induces disassembly of actin filaments in conjunction with ADF/cofilin family proteins. Enhances cofilin-mediated actin severing. Involved in cytokinesis. Involved in chemotactic cell migration by restricting lamellipodial membrane protrusions. Involved in myocardium sarcomere organization. Required for cardiomyocyte growth and maintenance. Involved in megakaryocyte maturation and platelet shedding. Required for the establishment of planar cell polarity (PCP) during follicular epithelium development and for cell shape changes during PCP; the function seems to implicate cooperation with CFL1 and/or DSTN/ADF. Involved in the generation/maintenance of cortical tension. Involved in assembly and maintenance of epithelial apical cell junctions and plays a role in the organization of the perijunctional actomyosin belt (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0051015 actin filament binding", "go_cellular_component": "GO:0002102 podosome;GO:0030864 cortical actin cytoskeleton", "go_biological_process": "GO:0045214 sarcomere organization;GO:0040011 locomotion;GO:0030042 actin filament depolymerization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2KJH4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KJH6-1", "uniprot_id": "SERPH_BOVIN", "mass": 46507.0, "length": 418, "protein_name": "Serpin H1", "gene_name": "SERPINH1", "organism": "Bovine", "refseq_name": "serpin H1 precursor", "refseq_ac": "NP_001039528", "gene_names_uniprotkb": "SERPINH1", "gene_names_refseq": "SERPINH1", "protein_names_uniprotkb": "Serpin H1; Collagen-binding protein; Colligin", "protein_names_refseq": "collagen-binding protein; colligin; serpin H1 precursor; serpin H1; serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)", "tax_id": 9913, "disease": "", "pathway": " (bta:510850); (R-BTA-1650814)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Binds specifically to collagen. Could be involved as a chaperone in the biosynthetic pathway of collagen (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004867 serine-type endopeptidase inhibitor activity;GO:0051082 unfolded protein binding;GO:0005518 collagen binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005783 endoplasmic reticulum;GO:0005788 endoplasmic reticulum lumen;GO:0045121 membrane raft;GO:0005793 endoplasmic reticulum-Golgi intermediate compartment", "go_biological_process": "GO:0030199 collagen fibril organization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2KJH6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2KJJ5-1", "uniprot_id": "TBL3_BOVIN", "mass": 88084.0, "length": 800, "protein_name": "Transducin beta-like protein 3", "gene_name": "TBL3", "organism": "Bovine", "refseq_name": "transducin beta-like protein 3", "refseq_ac": "NP_001040084", "gene_names_uniprotkb": "TBL3", "gene_names_refseq": "TBL3", "protein_names_uniprotkb": "Transducin beta-like protein 3", "protein_names_refseq": "transducin beta-like protein 3", "tax_id": 9913, "disease": "", "pathway": " (bta:618429)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0034511 U3 snoRNA binding", "go_cellular_component": "GO:0005730 nucleolus;GO:0030686 90S preribosome;GO:0032040 small-subunit processome", "go_biological_process": "GO:0000472 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0042274 ribosomal small subunit biogenesis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2KJJ5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2LGB5-1", "uniprot_id": "TOLIP_BOVIN", "mass": 30082.0, "length": 273, "protein_name": "Toll-interacting protein", "gene_name": "TOLLIP", "organism": "Bovine", "refseq_name": "toll-interacting protein", "refseq_ac": "NP_001035050", "gene_names_uniprotkb": "TOLLIP", "gene_names_refseq": "TOLLIP", "protein_names_uniprotkb": "Toll-interacting protein", "protein_names_refseq": "toll-interacting protein", "tax_id": 9913, "disease": "", "pathway": " (bta:539480); (R-BTA-6798695); (R-BTA-9020702)", "pathway_count": 3, "publication_count": 2, "publication_id_list": "16305752;16621030", "class_list": "", "function": "Component of the signaling pathway of IL-1 and Toll-like receptors (By similarity). Inhibits cell activation by microbial products (By similarity). Recruits IRAK1 to the IL-1 receptor complex (By similarity). Inhibits IRAK1 phosphorylation and kinase activity. Connects the ubiquitin pathway to autophagy by functioning as a ubiquitin-ATG8 family adapter and thus mediating autophagic clearance of ubiquitin conjugates (By similarity). The TOLLIP-dependent selective autophagy pathway plays an important role in clearance of cytotoxic polyQ proteins aggregates (By similarity). In a complex with TOM1, recruits ubiquitin-conjugated proteins onto early endosomes (By similarity). Binds to phosphatidylinositol 3-phosphate (PtdIns(3)P) (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q58D12", "ec_number_list": "", "go_molecular_function": "GO:0031624 ubiquitin conjugating enzyme binding;GO:0043130 ubiquitin binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005769 early endosome", "go_biological_process": "GO:0006954 inflammatory response;GO:0045087 innate immune response;GO:0006914 autophagy;GO:0016310 phosphorylation;GO:0006511 ubiquitin-dependent protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q2LGB5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2M2S2-1", "uniprot_id": "EMRE_BOVIN", "mass": 11450.0, "length": 107, "protein_name": "Essential MCU regulator, mitochondrial", "gene_name": "SMDT1", "organism": "Bovine", "refseq_name": "essential MCU regulator, mitochondrial precursor", "refseq_ac": "NP_001039402", "gene_names_uniprotkb": "SMDT1; EMRE", "gene_names_refseq": "C22orf32; C5H22orf32; SMDT1", "protein_names_uniprotkb": "Essential MCU regulator, mitochondrial; Single-pass membrane protein with aspartate-rich tail 1, mitochondrial", "protein_names_refseq": "UPF0466 protein C22orf32 homolog, mitochondrial; essential MCU regulator, mitochondrial precursor; essential MCU regulator, mitochondrial; single-pass membrane protein with aspartate-rich tail 1, mitochondrial", "tax_id": 9913, "disease": "", "pathway": " (bta:506149); (R-BTA-8949215); (R-BTA-8949664); (R-BTA-9837999)", "pathway_count": 4, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Essential regulatory subunit of the mitochondrial calcium uniporter complex (uniplex), a complex that mediates calcium uptake into mitochondria. Required to bridge the calcium-sensing proteins MICU1 with the calcium-conducting subunit MCU. Acts by mediating activation of MCU and retention of MICU1 to the MCU pore, in order to ensure tight regulation of the uniplex complex and appropriate responses to intracellular calcium signaling., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0030674 protein-macromolecule adaptor activity;GO:0099103 channel activator activity", "go_cellular_component": "GO:0005743 mitochondrial inner membrane;GO:1990246 uniplex complex", "go_biological_process": "GO:0006851 mitochondrial calcium ion transmembrane transport;GO:0036444 calcium import into the mitochondrion;GO:0051560 mitochondrial calcium ion homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2M2S2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2M2S7-1", "uniprot_id": "RPC10_BOVIN", "mass": 12422.0, "length": 108, "protein_name": "DNA-directed RNA polymerase III subunit RPC10", "gene_name": "POLR3K", "organism": "Bovine", "refseq_name": "DNA-directed RNA polymerase III subunit RPC10", "refseq_ac": "NP_001040082", "gene_names_uniprotkb": "POLR3K", "gene_names_refseq": "POLR3K", "protein_names_uniprotkb": "DNA-directed RNA polymerase III subunit RPC10; DNA-directed RNA polymerase III subunit K; RNA polymerase III subunit C10; RNA polymerase III subunit C11; RPC11", "protein_names_refseq": "DNA directed RNA polymerase III polypeptide K; DNA-directed RNA polymerase III subunit K; DNA-directed RNA polymerase III subunit RPC10; RNA polymerase III subunit C10; RNA polymerase III subunit C11; RPC11; polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa", "tax_id": 9913, "disease": "", "pathway": " (bta:618296)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Core component of RNA polymerase III (Pol III) which synthesizes small non-coding RNAs using the four ribonucleoside triphosphates as substrates (By similarity). Can mediate Pol I proofreading of the nascent RNA transcript. Anchors into the Pol III active site to constantly monitor transcription fidelity, cleaves mis-incorporated 5'-ribonucleotides and restarts the transcription process. Once Pol III reaches the poly(dT) termination signal, can induce Pol III clamp opening and transcription termination (By similarity). Pol III plays an important role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as a nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF-kappa-B through the RIG-I pathway (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0003676 nucleic acid binding;GO:0003899 DNA-directed RNA polymerase activity", "go_cellular_component": "GO:0005666 RNA polymerase III complex", "go_biological_process": "GO:0045087 innate immune response;GO:0051607 defense response to virus;GO:0006386 termination of RNA polymerase III transcription", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2M2S7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2M2S8-1", "uniprot_id": "ALKB7_BOVIN", "mass": 24589.0, "length": 221, "protein_name": "RNA demethylase ALKBH7, mitochondrial", "gene_name": "ALKBH7", "organism": "Bovine", "refseq_name": "RNA demethylase ALKBH7, mitochondrial precursor", "refseq_ac": "NP_001039867", "gene_names_uniprotkb": "ALKBH7", "gene_names_refseq": "ALKBH7", "protein_names_uniprotkb": "RNA demethylase ALKBH7, mitochondrial; 1.14.11.-; Alkylated DNA repair protein alkB homolog 7; Alpha-ketoglutarate-dependent dioxygenase alkB homolog 7, mitochondrial", "protein_names_refseq": "RNA demethylase ALKBH7, mitochondrial precursor; RNA demethylase ALKBH7, mitochondrial; alkB, alkylation repair homolog 7; alkylated DNA repair protein alkB homolog 7; alpha-ketoglutarate-dependent dioxygenase alkB homolog 7, mitochondrial; probable alpha-ketoglutarate-dependent dioxygenase ABH7", "tax_id": 9913, "disease": "", "pathway": " (bta:535305)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "RNA demethylase that demethylates N(2)-dimethylguanosine and N(1)-methyladenosine within mitochondrial pre-tRNA regions. This demethylation activity plays a crucial role in regulating the processing of nascent polycistronic mitochondrial RNA, thereby influencing mitochondrial gene expression and overall mitochondrial activity (By similarity). In response to extensive DNA damage is required for programmed necrosis induced by alkylation and oxidation. Acts by triggering the collapse of mitochondrial membrane potential and loss of mitochondrial function that leads to energy depletion and cell death (By similarity). Involved in fatty acid metabolism (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.14.11.51;4.2.99.18;1.14.11.33;1.14.11.-", "go_molecular_function": "GO:0046872 metal ion binding;GO:1990984 tRNA demethylase activity;GO:0035515 oxidative RNA demethylase activity", "go_cellular_component": "GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0006631 fatty acid metabolic process;GO:0006974 DNA damage response;GO:0010883 regulation of lipid storage;GO:1902445 regulation of mitochondrial membrane permeability involved in programmed necrotic cell death;GO:0035513 oxidative RNA demethylation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2M2S8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2M2U3-1", "uniprot_id": "LTOR4_BOVIN", "mass": 10686.0, "length": 99, "protein_name": "Ragulator complex protein LAMTOR4", "gene_name": "LAMTOR4", "organism": "Bovine", "refseq_name": "ragulator complex protein LAMTOR4", "refseq_ac": "NP_001160079", "gene_names_uniprotkb": "LAMTOR4", "gene_names_refseq": "C25H7orf59; LAMTOR4", "protein_names_uniprotkb": "Ragulator complex protein LAMTOR4; Late endosomal/lysosomal adaptor and MAPK and MTOR activator 4", "protein_names_refseq": "CG14977-PA-like; UPF0539 protein C7orf59 homolog; late endosomal/lysosomal adaptor and MAPK and MTOR activator 4; ragulator complex protein LAMTOR4", "tax_id": 9913, "disease": "", "pathway": " (bta:511903); (R-BTA-1632852); (R-BTA-165159); (R-BTA-166208); (R-BTA-380972); (R-BTA-5628897); (R-BTA-8943724); (R-BTA-9639288)", "pathway_count": 8, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V-ATPase, the Ragulator plays a dual role for the small GTPases Rag (RagA/RRAGA, RagB/RRAGB, RagC/RRAGC and/or RagD/RRAGD): it (1) acts as a guanine nucleotide exchange factor (GEF), activating the small GTPases Rag and (2) mediates recruitment of Rag GTPases to the lysosome membrane. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005764 lysosome;GO:0005765 lysosomal membrane;GO:0071986 Ragulator complex", "go_biological_process": "GO:1904263 positive regulation of TORC1 signaling;GO:0032008 positive regulation of TOR signaling;GO:0071230 cellular response to amino acid stimulus;GO:0061462 protein localization to lysosome;GO:0008361 regulation of cell size", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2M2U3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q32PG1-1", "uniprot_id": "AP3B1_BOVIN", "mass": 119968.0, "length": 1084, "protein_name": "AP-3 complex subunit beta-1", "gene_name": "AP3B1", "organism": "Bovine", "refseq_name": "AP-3 complex subunit beta-1", "refseq_ac": "NP_001070002", "gene_names_uniprotkb": "AP3B1", "gene_names_refseq": "AP3B1", "protein_names_uniprotkb": "AP-3 complex subunit beta-1; Adaptor protein complex AP-3 subunit beta-1; Adaptor-related protein complex 3 subunit beta-1; Beta-3A-adaptin; Clathrin assembly protein complex 3 beta-1 large chain", "protein_names_refseq": "AP-3 complex subunit beta-1; adapter-related protein complex 3 subunit beta-1; adaptor protein complex AP-3 beta-1 subunit; adaptor protein complex AP-3 subunit beta-1; adaptor related protein complex 3 beta 1 subunit; beta-3A-adaptin; beta3A-adaptin; clathrin assembly protein complex 3 beta-1 large chain", "tax_id": 9913, "disease": "", "pathway": " (bta:767602); (R-BTA-432722)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0030742 GTP-dependent protein binding;GO:0019903 protein phosphatase binding", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0030665 clathrin-coated vesicle membrane;GO:0030123 AP-3 adaptor complex;GO:0030131 clathrin adaptor complex;GO:1904115 axon cytoplasm", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0016192 vesicle-mediated transport;GO:0008089 anterograde axonal transport;GO:0048490 anterograde synaptic vesicle transport;GO:0032438 melanosome organization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q32PG1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3SZV7-1", "uniprot_id": "HEMO_BOVIN", "mass": 52209.0, "length": 459, "protein_name": "Hemopexin", "gene_name": "HPX", "organism": "Bovine", "refseq_name": "hemopexin precursor", "refseq_ac": "NP_001029784", "gene_names_uniprotkb": "HPX", "gene_names_refseq": "HPX", "protein_names_uniprotkb": "Hemopexin", "protein_names_refseq": "hemopexin precursor", "tax_id": 9913, "disease": "", "pathway": " (bta:534509); (R-BTA-2168880)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "29016670;30573663", "class_list": "", "function": "Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Two glycoproteins, AHSG and HPX, represent a pivotal glycoprotein of the cytoprotective activity for WN1316, showing a concrete evidence for the novel glycan-independent function of serum glycoproteins in neuroprotective drug efficacy. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0046872 metal ion binding;GO:0015232 heme transmembrane transporter activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005576 extracellular region", "go_biological_process": "GO:0006879 intracellular iron ion homeostasis;GO:0042168 heme metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q3SZV7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2TBG8-1", "uniprot_id": "UCHL3_BOVIN", "mass": 26182.0, "length": 230, "protein_name": "Ubiquitin carboxyl-terminal hydrolase isozyme L3", "gene_name": "UCHL3", "organism": "Bovine", "refseq_name": "ubiquitin carboxyl-terminal hydrolase isozyme L3", "refseq_ac": "NP_001035631", "gene_names_uniprotkb": "UCHL3", "gene_names_refseq": "UCHL3", "protein_names_uniprotkb": "Ubiquitin carboxyl-terminal hydrolase isozyme L3; 3.4.19.12; UCH-L3; Ubiquitin thioesterase L3", "protein_names_refseq": "UCH-L3; ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase); ubiquitin carboxyl-terminal hydrolase isozyme L3; ubiquitin thioesterase L3; ubiquitin thiolesterase", "tax_id": 9913, "disease": "", "pathway": " (bta:520170); (R-BTA-5689603); (R-BTA-8866652); (R-BTA-8951664)", "pathway_count": 4, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Deubiquitinating enzyme (DUB) that controls levels of cellular ubiquitin through processing of ubiquitin precursors and ubiquitinated proteins. Thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of either ubiquitin or NEDD8. Has a 10-fold preference for Arg and Lys at position P3'', and exhibits a preference towards 'Lys-48'-linked ubiquitin chains (By similarity). Can hydrolyze UBB(+1), a mutated form of ubiquitin which is not effectively degraded by the proteasome and is associated with neurodegenerative disorders (By similarity). Involved in DNA repair via homologous recombination (HR) by mediating deubiquitination of RAD51 in response to DNA damage, promoting interaction between RAD51 and BRCA2 (By similarity). Deubiquitinates ENAC in apical compartments, thereby regulating apical membrane recycling. Indirectly increases the phosphorylation of IGFIR, AKT and FOXO1 and promotes insulin-signaling and insulin-induced adipogenesis. Required for stress-response retinal, skeletal muscle and germ cell maintenance. May be involved in working memory (By similarity)., [UniProtKB, UniProtKB, UniProtKB]; Ubiquitin-protein hydrolase is involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.4.19.12", "go_molecular_function": "GO:0004843 cysteine-type deubiquitinase activity;GO:0043130 ubiquitin binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0016579 protein deubiquitination;GO:0006511 ubiquitin-dependent protein catabolic process;GO:0030163 protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2TBG8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3MHH1-1", "uniprot_id": "SHQ1_BOVIN", "mass": 65067.0, "length": 579, "protein_name": "Protein SHQ1 homolog", "gene_name": "SHQ1", "organism": "Bovine", "refseq_name": "protein SHQ1 homolog", "refseq_ac": "NP_001030221", "gene_names_uniprotkb": "SHQ1", "gene_names_refseq": "SHQ1", "protein_names_uniprotkb": "Protein SHQ1 homolog", "protein_names_refseq": "SHQ1 homolog; protein SHQ1 homolog", "tax_id": 9913, "disease": "", "pathway": " (bta:507486); (R-BTA-171319)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Required for the quantitative accumulation of H/ACA ribonucleoproteins (RNPs), including telomerase, probably through the stabilization of DKC1, from the time of its synthesis until its association with NOP10, NHP2, and NAF1 at the nascent H/ACA RNA., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0051082 unfolded protein binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0022618 protein-RNA complex assembly;GO:0000493 box H/ACA snoRNP assembly", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q3MHH1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3T0E5-1", "uniprot_id": "APMAP_BOVIN", "mass": 46091.0, "length": 412, "protein_name": "Adipocyte plasma membrane-associated protein", "gene_name": "APMAP", "organism": "Bovine", "refseq_name": "adipocyte plasma membrane-associated protein", "refseq_ac": "NP_001030490", "gene_names_uniprotkb": "APMAP", "gene_names_refseq": "APMAP; C13H20orf3", "protein_names_uniprotkb": "Adipocyte plasma membrane-associated protein", "protein_names_refseq": "adipocyte plasma membrane-associated protein", "tax_id": 9913, "disease": "", "pathway": " (bta:535740)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Exhibits strong arylesterase activity with beta-naphthyl acetate and phenyl acetate. May play a role in adipocyte differentiation (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004064 arylesterase activity", "go_cellular_component": "GO:0016020 membrane;GO:0009986 cell surface", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q3T0E5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3T099-1", "uniprot_id": "SYWM_BOVIN", "mass": 40205.0, "length": 360, "protein_name": "Tryptophan--tRNA ligase, mitochondrial", "gene_name": "WARS2", "organism": "Bovine", "refseq_name": "tryptophan--tRNA ligase, mitochondrial precursor", "refseq_ac": "NP_001029754", "gene_names_uniprotkb": "WARS2", "gene_names_refseq": "WARS2", "protein_names_uniprotkb": "Tryptophan--tRNA ligase, mitochondrial; (Mt)TrpRS; 6.1.1.2; TrpRS; Tryptophanyl-tRNA synthetase", "protein_names_refseq": "(Mt)TrpRS; mitochondrial tryptophanyl-tRNA synthetase 2; trpRS; tryptophan--tRNA ligase, mitochondrial precursor; tryptophan--tRNA ligase, mitochondrial; tryptophanyl-tRNA synthetase, mitochondrial", "tax_id": 9913, "disease": "", "pathway": " (bta:532903)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalyzes the attachment of tryptophan to tRNA(Trp) in a two-step reaction: tryptophan is first activated by ATP to form Trp-AMP and then transferred to the acceptor end of tRNA(Trp)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "6.1.1.2", "go_molecular_function": "GO:0005524 ATP binding;GO:0004830 tryptophan-tRNA ligase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0070183 mitochondrial tryptophanyl-tRNA aminoacylation;GO:0006436 tryptophanyl-tRNA aminoacylation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q3T099-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2NL37-1", "uniprot_id": "BCCIP_BOVIN", "mass": 35184.0, "length": 306, "protein_name": "BRCA2 and CDKN1A-interacting protein", "gene_name": "BCCIP", "organism": "Bovine", "refseq_name": "BRCA2 and CDKN1A-interacting protein", "refseq_ac": "NP_001039587", "gene_names_uniprotkb": "BCCIP", "gene_names_refseq": "BCCIP", "protein_names_uniprotkb": "BRCA2 and CDKN1A-interacting protein", "protein_names_refseq": "BRCA2 and CDKN1A-interacting protein", "tax_id": 9913, "disease": "", "pathway": " (bta:512466)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "During interphase, required for microtubule organizing and anchoring activities. During mitosis, required for the organization and stabilization of the spindle pole. May promote cell cycle arrest by enhancing the inhibition of CDK2 activity by CDKN1A. May be required for repair of DNA damage by homologous recombination in conjunction with BRCA2. May not be involved in non-homologous end joining (NHEJ)., [UniProtKB, UniProtKB]; May promote cell cycle arrest by enhancing the inhibition of CDK2 activity by CDKN1A. May be required for repair of DNA damage by homologous recombination in conjunction with BRCA2. May not be involved in non-homologous end joining (NHEJ)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q1JPI1", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005813 centrosome;GO:0005814 centriole;GO:0097431 mitotic spindle pole;GO:0000922 spindle pole", "go_biological_process": "GO:0006281 DNA repair;GO:0090307 mitotic spindle assembly;GO:0000226 microtubule cytoskeleton organization;GO:0007052 mitotic spindle organization;GO:0034453 microtubule anchoring", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q2NL37-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3SZX8-1", "uniprot_id": "CCD25_BOVIN", "mass": 24618.0, "length": 208, "protein_name": "Coiled-coil domain-containing protein 25", "gene_name": "CCDC25", "organism": "Bovine", "refseq_name": "coiled-coil domain-containing protein 25", "refseq_ac": "NP_001030216", "gene_names_uniprotkb": "CCDC25", "gene_names_refseq": "CCDC25", "protein_names_uniprotkb": "Coiled-coil domain-containing protein 25", "protein_names_refseq": "coiled-coil domain-containing protein 25", "tax_id": 9913, "disease": "", "pathway": " (bta:507275)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Transmembrane receptor that senses neutrophil extracellular traps (NETs) and triggers the ILK-PARVB pathway to enhance cell motility. NETs are mainly composed of DNA fibers and are released by neutrophils to bind pathogens during inflammation. Formation of NETs is also associated with cancer metastasis, NET-DNA acting as a chemotactic factor to attract cancer cells. Specifically binds NETs on its extracellular region, in particular the 8-OHdG-enriched DNA present in NETs, and recruits ILK, initiating the ILK-PARVB cascade to induce cytoskeleton rearrangement and directional migration of cells., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0012505 endomembrane system", "go_biological_process": "GO:2000147 positive regulation of cell motility", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q3SZX8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q32LE9-1", "uniprot_id": "CSRP2_BOVIN", "mass": 20954.0, "length": 193, "protein_name": "Cysteine and glycine-rich protein 2", "gene_name": "CSRP2", "organism": "Bovine", "refseq_name": "cysteine and glycine-rich protein 2", "refseq_ac": "NP_001033272", "gene_names_uniprotkb": "CSRP2", "gene_names_refseq": "CSRP2", "protein_names_uniprotkb": "Cysteine and glycine-rich protein 2; CRP2; Cysteine-rich protein 2", "protein_names_refseq": "CRP2; cysteine and glycine-rich protein 2; cysteine-rich protein 2", "tax_id": 9913, "disease": "", "pathway": " (bta:539381)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Could play a role in neuronal development., [UniProtKB, UniProtKB]; Drastically down-regulated in response to PDGF-BB or cell injury, that promote smooth muscle cell proliferation and dedifferentiation. Seems to play a role in the development of the embryonic vascular system (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0046872 metal ion binding;GO:0008307 structural constituent of muscle;GO:0042805 actinin binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0030018 Z disc", "go_biological_process": "GO:0045214 sarcomere organization;GO:0060537 muscle tissue development;GO:0030154 cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q32LE9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3ZBF0-1", "uniprot_id": "NADE_BOVIN", "mass": 79400.0, "length": 706, "protein_name": "Glutamine-dependent NAD(+) synthetase", "gene_name": "NADSYN1", "organism": "Bovine", "refseq_name": "glutamine-dependent NAD(+) synthetase", "refseq_ac": "NP_001029615", "gene_names_uniprotkb": "NADSYN1", "gene_names_refseq": "NADSYN1", "protein_names_uniprotkb": "Glutamine-dependent NAD(+) synthetase; 6.3.5.1; NAD(+) synthase [glutamine-hydrolyzing]; NAD(+) synthetase", "protein_names_refseq": "NAD(+) synthase; NAD(+) synthetase 1; glutamine-dependent NAD(+) synthetase", "tax_id": 9913, "disease": "", "pathway": " (bta:513400); (R-BTA-196807)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "6.3.5.1", "go_molecular_function": "GO:0005524 ATP binding;GO:0003952 NAD+ synthase (glutamine-hydrolyzing) activity;GO:0004359 glutaminase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0009435 NAD+ biosynthetic process;GO:0034354 'de novo' NAD+ biosynthetic process from L-tryptophan;GO:0034355 NAD+ biosynthetic process via the salvage pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q3ZBF0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3SYT0-1", "uniprot_id": "OBRG_BOVIN", "mass": 14228.0, "length": 131, "protein_name": "Leptin receptor gene-related protein", "gene_name": "LEPROT", "organism": "Bovine", "refseq_name": "leptin receptor gene-related protein", "refseq_ac": "NP_001029913", "gene_names_uniprotkb": "LEPROT; LEPR; OBR", "gene_names_refseq": "LEPROT; OB-RGRP", "protein_names_uniprotkb": "Leptin receptor gene-related protein; Endospanin-1; OB-R gene-related protein; OB-RGRP", "protein_names_refseq": "OB-R gene-related protein; endospanin-1; leptin receptor gene-related protein", "tax_id": 9913, "disease": "", "pathway": " (bta:613665)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Negatively regulates leptin receptor (LEPR) cell surface expression, and thus decreases response to leptin/LEP. Negatively regulates growth hormone (GH) receptor cell surface expression in liver. May play a role in liver resistance to GH during periods of reduced nutrient availability (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005768 endosome;GO:0010008 endosome membrane", "go_biological_process": "GO:0060400 negative regulation of growth hormone receptor signaling pathway;GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q3SYT0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q32KZ1-1", "uniprot_id": "IF3M_BOVIN", "mass": 30619.0, "length": 273, "protein_name": "Translation initiation factor IF-3, mitochondrial", "gene_name": "MTIF3", "organism": "Bovine", "refseq_name": "translation initiation factor IF-3, mitochondrial precursor", "refseq_ac": "NP_001033155", "gene_names_uniprotkb": "MTIF3", "gene_names_refseq": "MTIF3", "protein_names_uniprotkb": "Translation initiation factor IF-3, mitochondrial; IF-3(Mt); IF-3Mt; IF3(mt); IF3mt", "protein_names_refseq": "IF-3(Mt); IF-3Mt; IF3(mt); IF3mt; translation initiation factor IF-3, mitochondrial precursor; translation initiation factor IF-3, mitochondrial", "tax_id": 9913, "disease": "", "pathway": " (bta:509987)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "IF-3 binds to the 28S ribosomal subunit and shifts the equilibrium between 55S ribosomes and their 39S and 28S subunits in favor of the free subunits, thus enhancing the availability of 28S subunits on which protein synthesis initiation begins., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0043024 ribosomal small subunit binding;GO:0008135 translation factor activity, RNA binding;GO:0043022 ribosome binding;GO:0003743 translation initiation factor activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0032790 ribosome disassembly;GO:0070124 mitochondrial translational initiation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q32KZ1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3SYR3-1", "uniprot_id": "ABEC2_BOVIN", "mass": 25962.0, "length": 224, "protein_name": "Probable C->U-editing enzyme APOBEC-2", "gene_name": "APOBEC2", "organism": "Bovine", "refseq_name": "probable C->U-editing enzyme APOBEC-2", "refseq_ac": "NP_001029527", "gene_names_uniprotkb": "APOBEC2", "gene_names_refseq": "APOBEC2", "protein_names_uniprotkb": "Probable C->U-editing enzyme APOBEC-2; 3.5.4.36; mRNA(cytosine(6666)) deaminase 2", "protein_names_refseq": "apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2; mRNA(cytosine(6666)) deaminase 2; probable C->U-editing enzyme APOBEC-2", "tax_id": 9913, "disease": "", "pathway": " (bta:509619); (R-BTA-72200); (R-BTA-75094)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Probable C to U editing enzyme whose physiological substrate is not yet known. Does not display detectable apoB mRNA editing. Has a low intrinsic cytidine deaminase activity. May play a role in the epigenetic regulation of gene expression through the process of active DNA demethylation., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.5.4.36;3.5.4.38", "go_molecular_function": "GO:0003723 RNA binding;GO:0004126 cytidine deaminase activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005654 nucleoplasm;GO:0016020 membrane", "go_biological_process": "GO:0044029 positive regulation of gene expression via chromosomal CpG island demethylation;GO:0006397 mRNA processing;GO:0016554 cytidine to uridine editing", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q3SYR3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3MI05-1", "uniprot_id": "PPGB_BOVIN", "mass": 53980.0, "length": 479, "protein_name": "Lysosomal protective protein", "gene_name": "CTSA", "organism": "Bovine", "refseq_name": "lysosomal protective protein precursor", "refseq_ac": "NP_001030403", "gene_names_uniprotkb": "CTSA; PPGB", "gene_names_refseq": "CTSA; PPCA", "protein_names_uniprotkb": "Lysosomal protective protein; 3.4.16.5; Cathepsin A", "protein_names_refseq": "lysosomal protective protein precursor; lysosomal protective protein; protective protein for beta-galactosidase", "tax_id": 9913, "disease": "", "pathway": " (bta:518169); (R-BTA-2132295); (R-BTA-4085001); (R-BTA-6798695); (R-BTA-9840310)", "pathway_count": 5, "publication_count": 1, "publication_id_list": "20163628", "class_list": "", "function": "PPGB gene is not responsible for the lysosomal storage disease of Japanese Black cattle., [RefSeq, PubMed]; Protective protein appears to be essential for both the activity of beta-galactosidase and neuraminidase, it associates with these enzymes and exerts a protective function necessary for their stability and activity. This protein is also a carboxypeptidase and can deamidate tachykinins., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "5.3.4.1;3.2.1.23;3.1.3.16;3.1.6.4;3.1.6.14;1.1.1.205;3.2.1.18;3.4.19.9;3.2.1.-;2.7.10.2;3.5.1.26;3.4.23.5;2.4.1.1;1.6.5.5;3.5.4.4;3.2.1.51;3.6.4.6;3.2.1.52;1.11.1.27;3.1.1.4;2.3.1.23;1.6.2.2;3.4.22.1;3.4.22.27;3.4.22.15;2.7.11.24;3.2.1.17;3.1.6.8;3.2.1.24;3.5.3.1;2.3.3.8;3.4.16.5;3.4.16.-;3.6.1.-;3.4.22.38", "go_molecular_function": "GO:0004185 serine-type carboxypeptidase activity", "go_cellular_component": "GO:0005764 lysosome", "go_biological_process": "GO:1904715 negative regulation of chaperone-mediated autophagy;GO:0006508 proteolysis;GO:0031647 regulation of protein stability", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q3MI05-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q32KV4-1", "uniprot_id": "DC2L1_BOVIN", "mass": 39712.0, "length": 351, "protein_name": "Cytoplasmic dynein 2 light intermediate chain 1", "gene_name": "DYNC2LI1", "organism": "Bovine", "refseq_name": "cytoplasmic dynein 2 light intermediate chain 1", "refseq_ac": "NP_001033140", "gene_names_uniprotkb": "DYNC2LI1", "gene_names_refseq": "DYNC2LI1", "protein_names_uniprotkb": "Cytoplasmic dynein 2 light intermediate chain 1", "protein_names_refseq": "cytoplasmic dynein 2 light intermediate chain 1", "tax_id": 9913, "disease": "", "pathway": " (bta:507311); (R-BTA-5620924)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 2 complex (dynein-2 complex), a motor protein complex that drives the movement of cargos along microtubules within cilia and flagella in concert with the intraflagellar transport (IFT) system, facilitating the assembly of these organelles. Involved in the regulation of ciliary length., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0045504 dynein heavy chain binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005813 centrosome;GO:0005874 microtubule;GO:0005930 axoneme;GO:0036064 ciliary basal body", "go_biological_process": "GO:0035735 intraciliary transport involved in cilium assembly;GO:1902017 regulation of cilium assembly;GO:0035721 intraciliary retrograde transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q32KV4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3SZI6-1", "uniprot_id": "RPN2_BOVIN", "mass": 69214.0, "length": 631, "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2", "gene_name": "RPN2", "organism": "Bovine", "refseq_name": "dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 precursor", "refseq_ac": "NP_001029776", "gene_names_uniprotkb": "RPN2", "gene_names_refseq": "RPN2", "protein_names_uniprotkb": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2; Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 63 kDa subunit; RPN-II; Ribophorin II; Ribophorin-2", "protein_names_refseq": "RPN-II; dolichyl-diphosphooligosaccharide--protein glycosyltransferase 63 kDa subunit; dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 precursor; dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2; ribophorin-2", "tax_id": 9913, "disease": "", "pathway": " (bta:534231); (R-BTA-9768727); (R-BTA-9931295)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0008250 oligosaccharyltransferase complex;GO:0160226 oligosaccharyltransferase complex A;GO:0160227 oligosaccharyltransferase complex B", "go_biological_process": "GO:0006487 protein N-linked glycosylation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q3SZI6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2TBX5-1", "uniprot_id": "SSRD_BOVIN", "mass": 18814.0, "length": 172, "protein_name": "Translocon-associated protein subunit delta", "gene_name": "SSR4", "organism": "Bovine", "refseq_name": "translocon-associated protein subunit delta precursor", "refseq_ac": "NP_001033592", "gene_names_uniprotkb": "SSR4", "gene_names_refseq": "SSR4", "protein_names_uniprotkb": "Translocon-associated protein subunit delta; SSR-delta; Signal sequence receptor subunit delta; TRAP-delta", "protein_names_refseq": "SSR-delta; TRAP-delta; signal sequence receptor subunit delta; signal sequence receptor, delta (translocon-associated protein delta); translocon-associated protein subunit delta precursor; translocon-associated protein subunit delta", "tax_id": 9913, "disease": "", "pathway": " (bta:504438)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane;GO:0012505 endomembrane system", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2TBX5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q32KS7-1", "uniprot_id": "ZN821_BOVIN", "mass": 46723.0, "length": 412, "protein_name": "Zinc finger protein 821", "gene_name": "ZNF821", "organism": "Bovine", "refseq_name": "zinc finger protein 821", "refseq_ac": "NP_001033241", "gene_names_uniprotkb": "ZNF821", "gene_names_refseq": "ZNF821", "protein_names_uniprotkb": "Zinc finger protein 821", "protein_names_refseq": "zinc finger protein 821", "tax_id": 9913, "disease": "", "pathway": " (bta:532668)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "May be involved in transcriptional regulation., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0003677 DNA binding;GO:1990837 sequence-specific double-stranded DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0016607 nuclear speck", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q32KS7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3T075-1", "uniprot_id": "STX8_BOVIN", "mass": 26760.0, "length": 236, "protein_name": "Syntaxin-8", "gene_name": "STX8", "organism": "Bovine", "refseq_name": "syntaxin-8", "refseq_ac": "NP_001071505", "gene_names_uniprotkb": "STX8", "gene_names_refseq": "STX8", "protein_names_uniprotkb": "Syntaxin-8", "protein_names_refseq": "syntaxin-8", "tax_id": 9913, "disease": "", "pathway": " (bta:613567)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Vesicle trafficking protein that functions in the early secretory pathway, possibly by mediating retrograde transport from cis-Golgi membranes to the ER., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0000149 SNARE binding;GO:0005484 SNAP receptor activity;GO:0019869 chloride channel inhibitor activity;GO:0031625 ubiquitin protein ligase binding;GO:0019905 syntaxin binding", "go_cellular_component": "GO:0012505 endomembrane system;GO:0005770 late endosome;GO:0031201 SNARE complex;GO:0016020 membrane;GO:0005769 early endosome", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0006906 vesicle fusion;GO:0048278 vesicle docking;GO:0045022 early endosome to late endosome transport;GO:1903076 regulation of protein localization to plasma membrane", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q3T075-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2NL31-1", "uniprot_id": "MTNA_BOVIN", "mass": 37826.0, "length": 358, "protein_name": "Methylthioribose-1-phosphate isomerase", "gene_name": "MRI1", "organism": "Bovine", "refseq_name": "methylthioribose-1-phosphate isomerase", "refseq_ac": "NP_001039852", "gene_names_uniprotkb": "MRI1", "gene_names_refseq": "MRI1", "protein_names_uniprotkb": "Methylthioribose-1-phosphate isomerase; 5.3.1.23; M1Pi; MTR-1-P isomerase; S-methyl-5-thioribose-1-phosphate isomerase; Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein", "protein_names_refseq": "M1Pi; MTR-1-P isomerase; S-methyl-5-thioribose-1-phosphate isomerase; methylthioribose-1-phosphate isomerase homolog; methylthioribose-1-phosphate isomerase; translation initiation factor eIF-2B subunit alpha/beta/delta-like protein", "tax_id": 9913, "disease": "", "pathway": " (bta:534734); (R-BTA-1237112)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P)., [UniProtKB, HAMAP, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "5.3.1.23", "go_molecular_function": "GO:0046523 S-methyl-5-thioribose-1-phosphate isomerase activity;GO:0042802 identical protein binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005654 nucleoplasm", "go_biological_process": "GO:0019509 L-methionine salvage from methylthioadenosine", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2NL31-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3T0Z7-1", "uniprot_id": "DHPR_BOVIN", "mass": 25504.0, "length": 242, "protein_name": "Dihydropteridine reductase", "gene_name": "QDPR", "organism": "Bovine", "refseq_name": "dihydropteridine reductase", "refseq_ac": "NP_001069960", "gene_names_uniprotkb": "QDPR", "gene_names_refseq": "QDPR", "protein_names_uniprotkb": "Dihydropteridine reductase; 1.5.1.34; HDHPR; Quinoid dihydropteridine reductase", "protein_names_refseq": "HDHPR; dihydropteridine reductase", "tax_id": 9913, "disease": "", "pathway": " (bta:618084); (R-BTA-8964208)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalyzes the conversion of quinonoid dihydrobiopterin into tetrahydrobiopterin., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.5.1.34", "go_molecular_function": "GO:0070402 NADPH binding;GO:0004155 6,7-dihydropteridine reductase activity;GO:0070404 NADH binding", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0006559 L-phenylalanine catabolic process;GO:0006729 tetrahydrobiopterin biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q3T0Z7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2T9Y0-1", "uniprot_id": "RSRC1_BOVIN", "mass": 38710.0, "length": 334, "protein_name": "Serine/Arginine-related protein 53", "gene_name": "RSRC1", "organism": "Bovine", "refseq_name": "serine/Arginine-related protein 53", "refseq_ac": "NP_001068872", "gene_names_uniprotkb": "RSRC1; SRRP53", "gene_names_refseq": "RSRC1; SRrp53", "protein_names_uniprotkb": "Serine/Arginine-related protein 53; Arginine/serine-rich coiled-coil protein 1; SRrp53", "protein_names_refseq": "arginine/serine-rich coiled-coil 1; arginine/serine-rich coiled-coil protein 1; serine/Arginine-related protein 53", "tax_id": 9913, "disease": "", "pathway": " (bta:509437)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Plays a role in pre-mRNA splicing. Involved both in the constitutive and regulation of pre-mRNA splicing. May have a role in the recognition of the 3' splice site during the second step of splicing (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0016607 nuclear speck", "go_biological_process": "GO:0006913 nucleocytoplasmic transport;GO:0000398 mRNA splicing, via spliceosome;GO:0000380 alternative mRNA splicing, via spliceosome", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2T9Y0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q32KS2-1", "uniprot_id": "DNAI1_BOVIN", "mass": 79894.0, "length": 702, "protein_name": "Dynein axonemal intermediate chain 1", "gene_name": "DNAI1", "organism": "Bovine", "refseq_name": "dynein axonemal intermediate chain 1", "refseq_ac": "NP_001033231", "gene_names_uniprotkb": "DNAI1", "gene_names_refseq": "DNAI1", "protein_names_uniprotkb": "Dynein axonemal intermediate chain 1; Axonemal dynein intermediate chain 1", "protein_names_refseq": "axonemal dynein intermediate chain 1; dynein axonemal intermediate chain 1; dynein intermediate chain 1, axonemal", "tax_id": 9913, "disease": "", "pathway": " (bta:524709)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of dynein, a family of motor proteins essential for movement along microtubules (By similarity). Required for structural and functional integrity of cilia (By similarity). Part of the dynein complex of respiratory cilia., [UniProtKB, UniProtKB]; Component of dynein, a family of motor proteins essential for movement along microtubules. Required for structural and functional integrity of cilia. Part of the dynein complex of respiratory cilia., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0045503 dynein light chain binding;GO:0045504 dynein heavy chain binding", "go_cellular_component": "GO:0005874 microtubule;GO:0036157 outer dynein arm;GO:0120293 dynein axonemal particle;GO:0005930 axoneme;GO:0030286 dynein complex", "go_biological_process": "GO:0007368 determination of left/right symmetry;GO:0003341 cilium movement;GO:0036158 outer dynein arm assembly;GO:0008286 insulin receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q32KS2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3SYW9-1", "uniprot_id": "CHTOP_BOVIN", "mass": 26427.0, "length": 248, "protein_name": "Chromatin target of PRMT1 protein", "gene_name": "CHTOP", "organism": "Bovine", "refseq_name": "chromatin target of PRMT1 protein", "refseq_ac": "NP_001030558", "gene_names_uniprotkb": "CHTOP; FOP", "gene_names_refseq": "C1orf77; C3H1orf77; CHTOP; FOP; SRAG", "protein_names_uniprotkb": "Chromatin target of PRMT1 protein; Friend of PRMT1 protein; SRAG; Small arginine- and glycine-rich protein", "protein_names_refseq": "Friend of PRMT1 protein; chromatin target of PRMT1 protein; small arginine- and glycine-rich protein", "tax_id": 9913, "disease": "", "pathway": " (bta:616638)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Plays an important role in the ligand-dependent activation of estrogen receptor target genes. May play a role in the silencing of fetal globin genes. Recruits the 5FMC complex to ZNF148, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes. Required for the tumorigenicity of glioblastoma cells. Binds to 5-hydroxymethylcytosine (5hmC) and associates with the methylosome complex containing PRMT1, PRMT5, MEP50 and ERH. The CHTOP-methylosome complex associated with 5hmC methylates H4R3 and transactivates genes involved in glioblastomagenesis (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding;GO:0008327 methyl-CpG binding", "go_cellular_component": "GO:0005730 nucleolus;GO:0016607 nuclear speck;GO:0000346 transcription export complex", "go_biological_process": "GO:0006338 chromatin remodeling;GO:0006351 DNA-templated transcription;GO:0006406 mRNA export from nucleus", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q3SYW9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3T0L1-1", "uniprot_id": "CENPH_BOVIN", "mass": 28064.0, "length": 244, "protein_name": "Centromere protein H", "gene_name": "CENPH", "organism": "Bovine", "refseq_name": "centromere protein H", "refseq_ac": "NP_001029408", "gene_names_uniprotkb": "CENPH", "gene_names_refseq": "CENPH", "protein_names_uniprotkb": "Centromere protein H; CENP-H", "protein_names_refseq": "CENP-H; centromere protein H", "tax_id": 9913, "disease": "", "pathway": " (bta:505284); (R-BTA-141430); (R-BTA-141444); (R-BTA-2467813); (R-BTA-2500257); (R-BTA-5663220); (R-BTA-606279); (R-BTA-9648025)", "pathway_count": 8, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0043515 kinetochore binding", "go_cellular_component": "GO:0005634 nucleus;GO:0000776 kinetochore;GO:0005654 nucleoplasm", "go_biological_process": "GO:0051382 kinetochore assembly;GO:0007059 chromosome segregation;GO:0007052 mitotic spindle organization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q3T0L1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q32LN7-1", "uniprot_id": "SKI8_BOVIN", "mass": 33569.0, "length": 305, "protein_name": "Superkiller complex protein 8", "gene_name": "SKIC8", "organism": "Bovine", "refseq_name": "superkiller complex protein 8", "refseq_ac": "NP_001033186", "gene_names_uniprotkb": "SKIC8; WDR61", "gene_names_refseq": "SKIC8; Ski8; WDR61", "protein_names_uniprotkb": "Superkiller complex protein 8; Ski8; WD repeat-containing protein 61, N-terminally processed; WD repeat-containing protein 61", "protein_names_refseq": "SKI8 subunit of superkiller complex protein; WD repeat domain 61; WD repeat-containing protein 61; superkiller complex protein 8", "tax_id": 9913, "disease": "", "pathway": " (bta:513208); (R-BTA-429958); (R-BTA-674695); (R-BTA-75955); (R-BTA-8866654); (R-BTA-9943411)", "pathway_count": 6, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of the PAF1 complex (PAF1C) which has multiple functions during transcription by RNA polymerase II and is implicated in regulation of development and maintenance of embryonic stem cell pluripotency. PAF1C associates with RNA polymerase II through interaction with POLR2A CTD non-phosphorylated and 'Ser-2'- and 'Ser-5'-phosphorylated forms and is involved in transcriptional elongation, acting both independently and synergistically with TCEA1 and in cooperation with the DSIF complex and HTATSF1. PAF1C is required for transcription of Hox and Wnt target genes. PAF1C is involved in hematopoiesis and stimulates transcriptional activity of KMT2A/MLL1; it promotes leukemogenesis through association with KMT2A/MLL1-rearranged oncoproteins, such as KMT2A/MLL1-MLLT3/AF9 and KMT2A/MLL1-MLLT1/ENL. PAF1C is involved in histone modifications such as ubiquitination of histone H2B and methylation on histone H3 'Lys-4' (H3K4me3). PAF1C recruits the RNF20/40 E3 ubiquitin-protein ligase complex and the E2 enzyme UBE2A or UBE2B to chromatin which mediate monoubiquitination of 'Lys-120' of histone H2B (H2BK120ub1); UB2A/B-mediated H2B ubiquitination is proposed to be coupled to transcription. PAF1C is involved in mRNA 3' end formation probably through association with cleavage and poly(A) factors. In case of infection by influenza A strain H3N2, PAF1C associates with viral NS1 protein, thereby regulating gene transcription. Required for mono- and trimethylation on histone H3 'Lys-4' (H3K4me3), dimethylation on histone H3 'Lys-79' (H3K4me3). Required for Hox gene transcription. Also acts as a component of the SKI complex, a multiprotein complex that assists the RNA-degrading exosome during the mRNA decay and quality-control pathways. The SKI complex catalyzes mRNA extraction from 80S ribosomal complexes in the 3'-5' direction and channels mRNA to the cytosolic exosome for degradation. SKI-mediated extraction of mRNA from stalled ribosomes allow binding of the Pelota-HBS1L complex and subsequent ribosome disassembly by ABCE1 for ribosome recycling., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0055087 Ski complex;GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0000791 euchromatin;GO:0016593 Cdc73/Paf1 complex", "go_biological_process": "GO:0072344 rescue of stalled ribosome;GO:0070478 nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay;GO:0016055 Wnt signaling pathway;GO:0006368 transcription elongation by RNA polymerase II;GO:0045638 negative regulation of myeloid cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q32LN7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3T0I5-1", "uniprot_id": "FIS1_BOVIN", "mass": 16938.0, "length": 152, "protein_name": "Mitochondrial fission 1 protein", "gene_name": "FIS1", "organism": "Bovine", "refseq_name": "mitochondrial fission 1 protein", "refseq_ac": "NP_001029956", "gene_names_uniprotkb": "FIS1", "gene_names_refseq": "FIS1", "protein_names_uniprotkb": "Mitochondrial fission 1 protein; Fis1 homolog", "protein_names_refseq": "fis1 homolog; fission 1 (mitochondrial outer membrane) homolog; mitochondrial fission 1 protein", "tax_id": 9913, "disease": "", "pathway": " (bta:615565); (R-BTA-9603798)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. Plays a minor role in the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface and mitochondrial fission. May not be essential for the assembly of functional fission complexes and the subsequent membrane scission event. Also mediates peroxisomal fission. May act when the products of fission are directed toward mitochondrial homeostasis, mitophagy, or apoptosis. Can induce cytochrome c release from the mitochondrion to the cytosol, ultimately leading to apoptosis., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0060090 molecular adaptor activity;GO:0008289 lipid binding", "go_cellular_component": "GO:0005741 mitochondrial outer membrane;GO:0005777 peroxisome;GO:0005778 peroxisomal membrane", "go_biological_process": "GO:0016559 peroxisome fission;GO:0006915 apoptotic process;GO:0000266 mitochondrial fission", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q3T0I5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q32P85-1", "uniprot_id": "DLRB2_BOVIN", "mass": 10846.0, "length": 96, "protein_name": "Dynein light chain roadblock-type 2", "gene_name": "DYNLRB2", "organism": "Bovine", "refseq_name": "dynein light chain roadblock-type 2", "refseq_ac": "NP_001070587", "gene_names_uniprotkb": "DYNLRB2; DNLC2B", "gene_names_refseq": "DYNLRB2", "protein_names_uniprotkb": "Dynein light chain roadblock-type 2; Dynein light chain 2B, cytoplasmic", "protein_names_refseq": "dynein light chain 2B, cytoplasmic; dynein light chain roadblock-type 2", "tax_id": 9913, "disease": "", "pathway": " (bta:768062); (R-BTA-5620924)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0045505 dynein intermediate chain binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005813 centrosome;GO:0005874 microtubule;GO:0005868 cytoplasmic dynein complex", "go_biological_process": "GO:0007018 microtubule-based movement", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q32P85-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2YDP3-1", "uniprot_id": "NC2A_BOVIN", "mass": 22324.0, "length": 205, "protein_name": "Dr1-associated corepressor", "gene_name": "DRAP1", "organism": "Bovine", "refseq_name": "dr1-associated corepressor", "refseq_ac": "NP_001069682", "gene_names_uniprotkb": "DRAP1", "gene_names_refseq": "DRAP1", "protein_names_uniprotkb": "Dr1-associated corepressor; Dr1-associated protein 1; NC2-alpha; Negative cofactor 2-alpha", "protein_names_refseq": "DR1-associated protein 1 (negative cofactor 2 alpha); NC2-alpha; dr1-associated corepressor; negative co-factor 2-alpha; negative cofactor 2-alpha", "tax_id": 9913, "disease": "", "pathway": " (bta:540345)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on its own (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0046982 protein heterodimerization activity;GO:0001046 core promoter sequence-specific DNA binding;GO:0016251 RNA polymerase II general transcription initiation factor activity;GO:0003677 DNA binding;GO:0042802 identical protein binding", "go_cellular_component": "GO:0005634 nucleus;GO:0017054 negative cofactor 2 complex;GO:0090575 RNA polymerase II transcription regulator complex", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006366 transcription by RNA polymerase II;GO:0006351 DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2YDP3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3ZBG6-1", "uniprot_id": "UNC50_BOVIN", "mass": 30352.0, "length": 259, "protein_name": "Protein unc-50 homolog", "gene_name": "UNC50", "organism": "Bovine", "refseq_name": "protein unc-50 homolog", "refseq_ac": "NP_001014921", "gene_names_uniprotkb": "UNC50", "gene_names_refseq": "UNC50", "protein_names_uniprotkb": "Protein unc-50 homolog", "protein_names_refseq": "protein unc-50 homolog", "tax_id": 9913, "disease": "", "pathway": " (bta:513629)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "Involved in the cell surface expression of neuronal nicotinic receptors (By similarity). Binds RNA (By similarity)., [UniProtKB, UniProtKB]; Involved in the cell surface expression of neuronal nicotinic receptors. Binds RNA., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q5E989", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005637 nuclear inner membrane;GO:0005794 Golgi apparatus", "go_biological_process": "GO:0034394 protein localization to cell surface", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q3ZBG6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3ZBH3-1", "uniprot_id": "CD151_BOVIN", "mass": 27987.0, "length": 253, "protein_name": "CD151 antigen", "gene_name": "CD151; CRACR2B", "organism": "Bovine", "refseq_name": "CD151 antigen", "refseq_ac": "NP_001030424", "gene_names_uniprotkb": "CD151; CRACR2B; CRACR2B", "gene_names_refseq": "CD151", "protein_names_uniprotkb": "CD151 antigen", "protein_names_refseq": "CD151 antigen; CD151 molecule (Raph blood group)", "tax_id": 9913, "disease": "", "pathway": " (bta:523328)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Structural component of specialized membrane microdomains known as tetraspanin-enriched microdomains (TERMs), which act as platforms for receptor clustering and signaling. Plays a role in various cellular and molecular mechanism through its association with both integrin and non-integrin proteins. These interactions facilitate critical cellular functions, including cell-to-cell communication, wound healing, platelet aggregation, trafficking, cell motility, and angiogenesis. Via interaction with JAM-A/F11R and integrin ITGA3:ITGB1, promotes the recruitment of signaling molecules such as RAC1, CDC42 and RhoGTPases to facilitate the polarization of epithelial cells and the reorganization of the actin cytoskeleton, which are critical steps in cell migration process. Regulates the glycosylation pattern of ITGA3:ITGB1 thereby modulating its activity. Plays an essential role in the maintenance of central laminin-binding integrin ITGA6:ITGB4-containing adhesion complexes. Essential for the proper assembly of the glomerular and tubular basement membranes in kidney. Contributes to T-cell activation by modulating integrin signaling leading to activation of downstream targets PTK2 and MAPK1/MAPK3., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005178 integrin binding;GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0016477 cell migration;GO:0002115 store-operated calcium entry", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q3ZBH3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3T0W0-1", "uniprot_id": "TM86B_BOVIN", "mass": 24681.0, "length": 224, "protein_name": "Lysoplasmalogenase TMEM86B", "gene_name": "PPP6R1; TMEM86B", "organism": "Bovine", "refseq_name": "lysoplasmalogenase TMEM86B", "refseq_ac": "NP_001029700", "gene_names_uniprotkb": "PPP6R1; TMEM86B; TMEM86B", "gene_names_refseq": "TMEM86B", "protein_names_uniprotkb": "Lysoplasmalogenase TMEM86B; 3.3.2.2; Transmembrane protein 86B", "protein_names_refseq": "lysoplasmalogenase TMEM86B; lysoplasmalogenase", "tax_id": 9913, "disease": "", "pathway": " (bta:511840); (bta:518466); (R-BTA-1482788); (R-BTA-204005)", "pathway_count": 4, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalyzes the hydrolysis of the vinyl ether bond of choline or ethanolamine lysoplasmalogens, forming fatty aldehyde and glycerophosphocholine or glycerophosphoethanolamine, respectively and is specific for the sn-2-deacylated (lyso) form of plasmalogen., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.3.2.2", "go_molecular_function": "GO:0047408 alkenylglycerophosphocholine hydrolase activity;GO:0047826 D-lysine 5,6-aminomutase activity;GO:0019888 protein phosphatase regulator activity;GO:0031267 small GTPase binding;GO:0019903 protein phosphatase binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0016020 membrane;GO:0005789 endoplasmic reticulum membrane;GO:0005829 cytosol;GO:0030027 lamellipodium", "go_biological_process": "GO:0046485 ether lipid metabolic process;GO:0009966 regulation of signal transduction;GO:0006629 lipid metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q3T0W0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3SZ41-1", "uniprot_id": "SUH_BOVIN", "mass": 54341.0, "length": 487, "protein_name": "Recombining binding protein suppressor of hairless", "gene_name": "RBPJ", "organism": "Bovine", "refseq_name": "recombining binding protein suppressor of hairless", "refseq_ac": "NP_001070469", "gene_names_uniprotkb": "RBPJ; RBPSUH", "gene_names_refseq": "RBPJ", "protein_names_uniprotkb": "Recombining binding protein suppressor of hairless; J kappa-recombination signal-binding protein; RBP-J kappa", "protein_names_refseq": "J kappa-recombination signal-binding protein; RBP-J kappa; recombining binding protein suppressor of hairless", "tax_id": 9913, "disease": "", "pathway": " (bta:767928); (R-BTA-350054); (R-BTA-8941856)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "33763686", "class_list": "", "function": "NOTCH signaling pathway is required for bovine early embryonic developmentdagger., [RefSeq, PubMed]; Transcriptional regulator that plays a central role in Notch signaling, a signaling pathway involved in cell-cell communication that regulates a broad spectrum of cell-fate determinations. Acts as a transcriptional repressor when it is not associated with Notch proteins. When associated with some NICD product of Notch proteins (Notch intracellular domain), it acts as a transcriptional activator that activates transcription of Notch target genes. Probably represses or activates transcription via the recruitment of chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins, respectively. Specifically binds to the immunoglobulin kappa-type J segment recombination signal sequence. Binds specifically to methylated DNA. Binds to the oxygen responsive element of COX4I2 and activates its transcription under hypoxia conditions (4% oxygen). Negatively regulates the phagocyte oxidative burst in response to bacterial infection by repressing transcription of NADPH oxidase subunits (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0043565 sequence-specific DNA binding;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0140297 DNA-binding transcription factor binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005667 transcription regulator complex;GO:0002193 MAML1-RBP-Jkappa- ICN1 complex", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0007219 Notch signaling pathway;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0048513 animal organ development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q3SZ41-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3T077-1", "uniprot_id": "TPPP2_BOVIN", "mass": 18564.0, "length": 171, "protein_name": "Tubulin polymerization-promoting protein family member 2", "gene_name": "TPPP2", "organism": "Bovine", "refseq_name": "tubulin polymerization-promoting protein family member 2", "refseq_ac": "NP_001029456", "gene_names_uniprotkb": "TPPP2", "gene_names_refseq": "TPPP2", "protein_names_uniprotkb": "Tubulin polymerization-promoting protein family member 2", "protein_names_refseq": "tubulin polymerization-promoting protein family member 2", "tax_id": 9913, "disease": "", "pathway": " (bta:507212)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Probable regulator of microtubule dynamics required for sperm motility (By similarity). In contrast to other members of the family, has no microtubule bundling activity (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0015631 tubulin binding", "go_cellular_component": "GO:0005829 cytosol;GO:0036126 sperm flagellum;GO:0005737 cytoplasm", "go_biological_process": "GO:0046785 microtubule polymerization;GO:0007283 spermatogenesis;GO:0030154 cell differentiation;GO:0001578 microtubule bundle formation;GO:0032273 positive regulation of protein polymerization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q3T077-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2NKS9-1", "uniprot_id": "BBLN_BOVIN", "mass": 9054.0, "length": 83, "protein_name": "Bublin coiled-coil protein", "gene_name": "BBLN", "organism": "Bovine", "refseq_name": "bublin coiled-coil protein", "refseq_ac": "NP_001181979", "gene_names_uniprotkb": "BBLN", "gene_names_refseq": "BBLN; C11H9orf16", "protein_names_uniprotkb": "Bublin coiled-coil protein; UPF0184 protein C9orf16 homolog", "protein_names_refseq": "UPF0184 protein C9orf16 homolog; bublin coiled-coil protein; chromosome 11 C9orf16 homolog", "tax_id": 9913, "disease": "", "pathway": " (bta:616015)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Essential for intermediate filament organization in intestinal cells, interacts with intermediate filament and regulates intestinal lumen morphology., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0060090 molecular adaptor activity", "go_cellular_component": "GO:0005828 kinetochore microtubule;GO:0030054 cell junction;GO:0005882 intermediate filament;GO:0120219 subapical part of cell;GO:0070161 anchoring junction", "go_biological_process": "GO:0045110 intermediate filament bundle assembly", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2NKS9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2TBY0-1", "uniprot_id": "SKA2_BOVIN", "mass": 14111.0, "length": 121, "protein_name": "SKA complex subunit 2", "gene_name": "SKA2", "organism": "Bovine", "refseq_name": "SKA complex subunit 2", "refseq_ac": "NP_001033668", "gene_names_uniprotkb": "SKA2; FAM33A", "gene_names_refseq": "FAM33A; SKA2", "protein_names_uniprotkb": "SKA complex subunit 2; Protein FAM33A; Spindle and kinetochore-associated protein 2", "protein_names_refseq": "SKA complex subunit 2; family with sequence similarity 33, member A; spindle and kinetochore-associated protein 2", "tax_id": 9913, "disease": "", "pathway": " (bta:615847)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of the SKA complex, a microtubule plus end-binding complex of the outer kinetochore that stabilizes spindle microtubule-kinetochore attachments, promotes alignment of chromosomes at the mitotic spindle equator (chromosome congression) and assists suppression of the spindle assembly checkpoint. Kinetochores, consisting of a centromere-associated inner segment and a microtubule-contacting outer segment, play a crucial role in chromosome segregation by mediating the physical connection between centromeric DNA and spindle microtubules. The outer kinetochore is made up of the ten-subunit KMN network complex, comprising the MIS12, NDC80 and KNL1 complexes, and auxiliary microtubule-associated components such as the SKA complex; together they connect the outer kinetochore with the inner kinetochore, bind microtubules, and mediate interactions with mitotic checkpoint proteins that delay anaphase until chromosomes are bioriented on the spindle. The SKA complex is loaded onto bioriented kinetochores and it facilitates chromosome congression by stabilizing microtubules together with MAPRE1, and end-on attachment of the NDC80 complex to depolymerizing spindle microtubules, thereby assisting the poleward-moving kinetochore in withstanding microtubule pulling forces. The complex associates with dynamic microtubule plus-ends and can track both depolymerizing and elongating microtubules. The complex recruits protein phosphatase 1 (PP1) to the kinetochore in prometaphase and metaphase, to oppose spindle assembly checkpoint signaling and promote the onset of anaphase. Binds directly to microtubules; but with a much lower affinity than SKA1 (By similarity). During meiosis the SKA complex stabilizes the meiotic spindle and is required for its migration to the cortex (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "F1MUQ7", "ec_number_list": "", "go_molecular_function": "GO:0008017 microtubule binding", "go_cellular_component": "GO:0005813 centrosome;GO:0005876 spindle microtubule;GO:0072687 meiotic spindle;GO:0000940 outer kinetochore", "go_biological_process": "GO:0031110 regulation of microtubule polymerization or depolymerization;GO:0051315 attachment of mitotic spindle microtubules to kinetochore;GO:0000278 mitotic cell cycle;GO:0007059 chromosome segregation;GO:0051301 cell division", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2TBY0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q32LP0-1", "uniprot_id": "URP2_BOVIN", "mass": 75783.0, "length": 665, "protein_name": "Fermitin family homolog 3", "gene_name": "FERMT3", "organism": "Bovine", "refseq_name": "fermitin family homolog 3", "refseq_ac": "NP_001032695", "gene_names_uniprotkb": "FERMT3; KIND3; URP2", "gene_names_refseq": "FERMT3; URP2", "protein_names_uniprotkb": "Fermitin family homolog 3; Kindlin-3; Unc-112-related protein 2", "protein_names_refseq": "UNC-112 related protein 2; fermitin family homolog 3; fermitin family member 3; kindlin-3; unc-112-related protein 2", "tax_id": 9913, "disease": "", "pathway": " (bta:525159); (R-BTA-114608)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Plays a central role in cell adhesion in hematopoietic cells. Acts by activating the integrin beta-1-3 (ITGB1, ITGB2 and ITGB3). Required for integrin-mediated platelet adhesion and leukocyte adhesion to endothelial cells. Required for activation of integrin beta-2 (ITGB2) in polymorphonuclear granulocytes (PMNs)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005178 integrin binding", "go_cellular_component": "GO:0002102 podosome;GO:0030055 cell-substrate junction;GO:0042995 cell projection;GO:0070161 anchoring junction", "go_biological_process": "GO:0007229 integrin-mediated signaling pathway;GO:0030335 positive regulation of cell migration;GO:0007160 cell-matrix adhesion;GO:0033632 regulation of cell-cell adhesion mediated by integrin;GO:0007159 leukocyte cell-cell adhesion", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q32LP0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3MI00-1", "uniprot_id": "DNJB1_BOVIN", "mass": 38217.0, "length": 340, "protein_name": "DnaJ homolog subfamily B member 1", "gene_name": "DNAJB1", "organism": "Bovine", "refseq_name": "dnaJ homolog subfamily B member 1", "refseq_ac": "NP_001028935", "gene_names_uniprotkb": "DNAJB1", "gene_names_refseq": "DNAJB1", "protein_names_uniprotkb": "DnaJ homolog subfamily B member 1", "protein_names_refseq": "DnaJ (Hsp40) homolog, subfamily B, member 1; dnaJ homolog subfamily B member 1", "tax_id": 9913, "disease": "", "pathway": " (bta:504207); (bta:538426); (R-BTA-3371453); (R-BTA-3371497); (R-BTA-3371568); (R-BTA-3371571); (R-BTA-5687128)", "pathway_count": 7, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Interacts with HSP70 and can stimulate its ATPase activity. Acts also with TTC1 as a chaperone adapter that regulates HSP70-dependent folding process by interacting with the HSP70 amino terminal region. Stimulates the association between HSC70 and HIP. Negatively regulates heat shock-induced HSF1 transcriptional activity during the attenuation and recovery phase period of the heat shock response. Stimulates ATP hydrolysis and the folding of unfolded proteins mediated by HSPA1A/B (in vitro)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0051082 unfolded protein binding;GO:0051117 ATPase binding;GO:0003714 transcription corepressor activity;GO:0001671 ATPase activator activity;GO:0030544 Hsp70 protein binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005829 cytosol", "go_biological_process": "GO:0090084 negative regulation of inclusion body assembly;GO:1903334 positive regulation of protein folding;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0034605 cellular response to heat;GO:0006457 protein folding", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q3MI00-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q32LG5-1", "uniprot_id": "REEP6_BOVIN", "mass": 20574.0, "length": 185, "protein_name": "Receptor expression-enhancing protein 6", "gene_name": "REEP6", "organism": "Bovine", "refseq_name": "receptor expression-enhancing protein 6", "refseq_ac": "NP_001033224", "gene_names_uniprotkb": "REEP6", "gene_names_refseq": "REEP6", "protein_names_uniprotkb": "Receptor expression-enhancing protein 6", "protein_names_refseq": "polyposis locus protein 1-like 1; receptor expression-enhancing protein 6", "tax_id": 9913, "disease": "", "pathway": " (bta:522480)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "28369466", "class_list": "", "function": "Required for correct function and survival of retinal photoreceptors (By similarity). Required for retinal development (By similarity). In rod photoreceptors, facilitates stability and/or trafficking of guanylate cyclases and is required to maintain endoplasmic reticulum and mitochondrial homeostasis (By similarity). May play a role in clathrin-coated intracellular vesicle trafficking of proteins from the endoplasmic reticulum to the retinal rod plasma membrane (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane;GO:0030665 clathrin-coated vesicle membrane;GO:0001917 photoreceptor inner segment", "go_biological_process": "GO:0050908 detection of light stimulus involved in visual perception", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q32LG5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q32PA9-1", "uniprot_id": "FKBP2_BOVIN", "mass": 15404.0, "length": 140, "protein_name": "Peptidyl-prolyl cis-trans isomerase FKBP2", "gene_name": "FKBP2", "organism": "Bovine", "refseq_name": "peptidyl-prolyl cis-trans isomerase FKBP2 isoform 2 precursor", "refseq_ac": "NP_001032558", "gene_names_uniprotkb": "FKBP2", "gene_names_refseq": "FKBP-2; FKBP2", "protein_names_uniprotkb": "Peptidyl-prolyl cis-trans isomerase FKBP2; 5.2.1.8; FK506-binding protein 2; FKBP-2; PPIase FKBP2; Rotamase", "protein_names_refseq": "FK506 binding protein 2, 13kDa; FK506-binding protein 2; PPIase FKBP2; peptidyl-prolyl cis-trans isomerase FKBP2 isoform 2 precursor; peptidyl-prolyl cis-trans isomerase FKBP2; rotamase", "tax_id": 9913, "disease": "", "pathway": " (bta:538998)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "5.2.1.8", "go_molecular_function": "GO:0003755 peptidyl-prolyl cis-trans isomerase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q32PA9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3SZU4-1", "uniprot_id": "CDO1_BOVIN", "mass": 23013.0, "length": 200, "protein_name": "Cysteine dioxygenase type 1", "gene_name": "CDO1", "organism": "Bovine", "refseq_name": "cysteine dioxygenase type 1", "refseq_ac": "NP_001029637", "gene_names_uniprotkb": "CDO1", "gene_names_refseq": "CDO1", "protein_names_uniprotkb": "Cysteine dioxygenase type 1; 1.13.11.20; CDO-I; CDO; Cysteine dioxygenase type I", "protein_names_refseq": "CDO-I; CDO; cysteine dioxygenase type 1; cysteine dioxygenase, type I", "tax_id": 9913, "disease": "", "pathway": " (bta:514462); (R-BTA-1614558)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "Catalyzes the oxidation of cysteine to cysteine sulfinic acid with addition of molecular dioxygen., [UniProtKB, UniProtKB, UniProtKB]; Rate-limiting enzyme of the cysteine catabolic process to taurine, which catalyzes the oxidation of cysteine to cysteine sulfinic acid with addition of molecular dioxygen., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.13.11.20", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0008198 ferrous iron binding;GO:0016151 nickel cation binding;GO:0017172 cysteine dioxygenase activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0042412 taurine biosynthetic process;GO:0019448 L-cysteine catabolic process;GO:0006534 cysteine metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q3SZU4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2TBU0-1", "uniprot_id": "HPT_BOVIN", "mass": 44859.0, "length": 401, "protein_name": "Haptoglobin", "gene_name": "HP", "organism": "Bovine", "refseq_name": "haptoglobin precursor", "refseq_ac": "NP_001035560", "gene_names_uniprotkb": "HP", "gene_names_refseq": "HP", "protein_names_uniprotkb": "Haptoglobin", "protein_names_refseq": "haptoglobin precursor; zonulin", "tax_id": 9913, "disease": "", "pathway": " (bta:280692)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "14960809;17227596;17681384;19094922;20391639;25358728;25704413;35040515", "class_list": "", "function": "An increase in serum amyloid A or haptoglobin in dairy cows with abomasal displacementis not specific for inflammation or bacterial infection; increased levels of either may indicate the presence of hepatic lipidosis., [RefSeq, PubMed]; As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidly cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Bovine granulocytes, isolated from peripheral blood of healthy cattle, contain abundant amounts of haptoglobin within the granules., [RefSeq, PubMed]; Haptoglobin concentration may be a useful indicator for cows with postpartum reproductive disorders., [RefSeq, PubMed]; Presence in the milk of the acute phase proteins (APP), haptoglobin (Hp) and serum amyloid A to see the relationships in cow composite and bulk tank milk samples., [RefSeq, PubMed]; Serum haptoglobin concentration and liver enzyme activity as indicators of systemic inflammatory response syndrome and survival of sick calves., [RefSeq, PubMed]; These data demonstrate that serum neutrophil haptoglobin-MMP 9 complexes appear sooner and decline more rapidly than other acute phase proteins. Publication Status: Online-Only, [RefSeq, PubMed]; These results indicate that it is possible to monitor the course of pyometra in cows based on the evaluation of the concentration of cytokines and Hp in the serum and uterine washings., [RefSeq, PubMed]; This study suggests that neutrophils and epithelial cells may play an essential role in elevating milk haptoglobin (Hp) in addition to previous suggestions that Hp may be derived from mammary tissues and circulation., [RefSeq, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004252 serine-type endopeptidase activity;GO:0016209 antioxidant activity;GO:0030492 hemoglobin binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0072562 blood microparticle;GO:0005576 extracellular region", "go_biological_process": "GO:0006953 acute-phase response;GO:0042742 defense response to bacterium;GO:0031638 zymogen activation;GO:0002376 immune system process;GO:0006508 proteolysis", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q2TBU0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3T105-1", "uniprot_id": "GALE_BOVIN", "mass": 38254.0, "length": 348, "protein_name": "UDP-glucose 4-epimerase", "gene_name": "GALE", "organism": "Bovine", "refseq_name": "UDP-glucose 4-epimerase", "refseq_ac": "NP_001193137", "gene_names_uniprotkb": "GALE", "gene_names_refseq": "GALE", "protein_names_uniprotkb": "UDP-glucose 4-epimerase; 5.1.3.2; 5.1.3.7; Galactowaldenase; UDP-GalNAc 4-epimerase; UDP-GlcNAc 4-epimerase; UDP-N-acetylglucosamine 4-epimerase; UDP-galactosamine 4-epimerase; UDP-galactose 4-epimerase", "protein_names_refseq": "UDP-GalNAc 4-epimerase; UDP-GlcNAc 4-epimerase; UDP-N-acetylglucosamine 4-epimerase; UDP-galactosamine 4-epimerase; UDP-glucose 4-epimerase; galactowaldenase", "tax_id": 9913, "disease": "", "pathway": " (bta:523154); (R-BTA-70370)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "19393038", "class_list": "", "function": "Catalyzes two distinct but analogous reactions: the reversible epimerization of UDP-glucose to UDP-galactose and the reversible epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. The reaction with UDP-Gal plays a critical role in the Leloir pathway of galactose catabolism in which galactose is converted to the glycolytic intermediate glucose 6-phosphate. It contributes to the catabolism of dietary galactose and enables the endogenous biosynthesis of both UDP-Gal and UDP-GalNAc when exogenous sources are limited. Both UDP-sugar interconversions are important in the synthesis of glycoproteins and glycolipids., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "F2Z4C3", "ec_number_list": "5.1.3.2;5.1.3.7", "go_molecular_function": "GO:0003978 UDP-glucose 4-epimerase activity;GO:0003974 UDP-N-acetylglucosamine 4-epimerase activity;GO:0042803 protein homodimerization activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0033499 galactose catabolic process via UDP-galactose, Leloir pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q3T105-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3T087-1", "uniprot_id": "RL11_BOVIN", "mass": 20252.0, "length": 178, "protein_name": "Large ribosomal subunit protein uL5", "gene_name": "RPL11", "organism": "Bovine", "refseq_name": "large ribosomal subunit protein uL5", "refseq_ac": "NP_001069049", "gene_names_uniprotkb": "RPL11", "gene_names_refseq": "RPL11", "protein_names_uniprotkb": "Large ribosomal subunit protein uL5; 60S ribosomal protein L11", "protein_names_refseq": "60S ribosomal protein L11; large ribosomal subunit protein uL5", "tax_id": 9913, "disease": "", "pathway": " (bta:512745); (R-BTA-156827); (R-BTA-1799339); (R-BTA-6791226); (R-BTA-72689); (R-BTA-72706); (R-BTA-975956); (R-BTA-975957); (R-BTA-9954709); (R-BTA-9954714); (R-BTA-9954716)", "pathway_count": 11, "publication_count": 1, "publication_id_list": "31625165", "class_list": "", "function": "A putative lethal recessive deletion in the bovine 60S ribosomal protein L11 gene (uL5) was confounded by a mutation in a pseudogene, [RefSeq, PubMed]; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel. As part of the 5S RNP/5S ribonucleoprotein particle it is an essential component of the LSU, required for its formation and the maturation of rRNAs. It also couples ribosome biogenesis to p53/TP53 activation. As part of the 5S RNP it accumulates in the nucleoplasm and inhibits MDM2, when ribosome biogenesis is perturbed, mediating the stabilization and the activation of TP53. Promotes nucleolar location of PML., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding;GO:0019843 rRNA binding;GO:0003735 structural constituent of ribosome;GO:0031625 ubiquitin protein ligase binding;GO:1990948 ubiquitin ligase inhibitor activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0022625 cytosolic large ribosomal subunit", "go_biological_process": "GO:0006412 translation;GO:0034504 protein localization to nucleus;GO:1901798 positive regulation of signal transduction by p53 class mediator;GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0006605 protein targeting", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q3T087-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3T0J9-1", "uniprot_id": "GNL3L_BOVIN", "mass": 64837.0, "length": 575, "protein_name": "Guanine nucleotide-binding protein-like 3-like protein", "gene_name": "GNL3L", "organism": "Bovine", "refseq_name": "guanine nucleotide-binding protein-like 3-like protein", "refseq_ac": "NP_001029479", "gene_names_uniprotkb": "GNL3L", "gene_names_refseq": "GNL3L", "protein_names_uniprotkb": "Guanine nucleotide-binding protein-like 3-like protein", "protein_names_refseq": "guanine nucleotide binding protein-like 3 (nucleolar)-like; guanine nucleotide-binding protein-like 3-like protein", "tax_id": 9913, "disease": "", "pathway": " (bta:507679)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Stabilizes TERF1 telomeric association by preventing TERF1 recruitment by PML. Stabilizes TERF1 protein by preventing its ubiquitination and hence proteasomal degradation. Does so by interfering with TERF1-binding to FBXO4 E3 ubiquitin-protein ligase. Required for cell proliferation. By stabilizing TRF1 protein during mitosis, promotes metaphase-to-anaphase transition. Stabilizes MDM2 protein by preventing its ubiquitination, and hence proteasomal degradation. By acting on MDM2, may affect TP53 activity. Required for normal processing of ribosomal pre-rRNA. Binds GTP., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005525 GTP binding", "go_cellular_component": "GO:0005730 nucleolus;GO:0005697 telomerase holoenzyme complex", "go_biological_process": "GO:0042254 ribosome biogenesis;GO:1904816 positive regulation of protein localization to chromosome, telomeric region;GO:0031334 positive regulation of protein-containing complex assembly;GO:0032211 negative regulation of telomere maintenance via telomerase;GO:0031647 regulation of protein stability", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q3T0J9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2TBP4-1", "uniprot_id": "POC1A_BOVIN", "mass": 45228.0, "length": 407, "protein_name": "POC1 centriolar protein homolog A", "gene_name": "POC1A", "organism": "Bovine", "refseq_name": "POC1 centriolar protein homolog A", "refseq_ac": "NP_001033649", "gene_names_uniprotkb": "POC1A; WDR51A", "gene_names_refseq": "POC1A; WDR51A", "protein_names_uniprotkb": "POC1 centriolar protein homolog A; WD repeat-containing protein 51A", "protein_names_refseq": "POC1 centriolar protein homolog A; WD repeat domain 51A; WD repeat-containing protein 51A", "tax_id": 9913, "disease": "", "pathway": " (bta:534489)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Plays an important role in centriole assembly and/or stability and ciliogenesis. Involved in early steps of centriole duplication, as well as in the later steps of centriole length control. Acts in concert with POC1B to ensure centriole integrity and proper mitotic spindle formation., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0000922 spindle pole;GO:0005813 centrosome;GO:0005814 centriole;GO:0036064 ciliary basal body;GO:0005737 cytoplasm", "go_biological_process": "GO:0060271 cilium assembly;GO:0030030 cell projection organization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2TBP4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2YDN1-1", "uniprot_id": "GP161_BOVIN", "mass": 58349.0, "length": 528, "protein_name": "G protein-coupled receptor 161", "gene_name": "GPR161", "organism": "Bovine", "refseq_name": "G protein-coupled receptor 161", "refseq_ac": "NP_001070534", "gene_names_uniprotkb": "GPR161", "gene_names_refseq": "GPR161", "protein_names_uniprotkb": "G protein-coupled receptor 161", "protein_names_refseq": "G protein-coupled receptor 161", "tax_id": 9913, "disease": "", "pathway": " (bta:768006); (R-BTA-5610787); (R-BTA-5632684)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "19393038", "class_list": "", "function": "G protein-coupled receptor that acts as a key inhibitor of the smoothened signaling pathway in primary cilia (By similarity). Inhibits the smoothened signaling pathway in absence of hedgehog (DHH, IHH or SHH) by promoting formation of the transcription repressor form of GLI2 and GLI3 transcription factors (By similarity). GPR161 activation triggers signaling via guanine nucleotide-binding protein G(s)/GNAS, mediating activation of adenylate cyclase activity and production of cAMP (By similarity). Increased cAMP levels activate PKA, promoting PKA-dependent processing of GLI2 and GLI3 transcription factors, leading to formation of transcription repressor GLI2R and GLI3R, which repress expression of target genes (By similarity). GPR161 also activates PKA by acting as a PKA-anchoring protein, which directly associates with type I PKA regulatory subunits (PRKAR1A and/or PRKAR1B), recruiting PKA followed by PKA-dependent processing of GLI2 and GLI3 transcription factors (By similarity). In presence of hedgehog, GPR161 is removed from primary cilia by smoothened (SMO), preventing its activity and allowing activation of the smoothened signaling (By similarity). In contrast to the majority of G protein-coupled receptors, it is not activated by a ligand and it either acts as a constitutively active receptor or as a mechanosensitive receptor (By similarity). Involved in regulation of the smoothened signaling pathway during early neural tube development, forelimb formation, skeletal development, embryonic cerebellar development and forebrain development (By similarity). Involved in the saltatory migration of neurons during brain development by acting as a mechanosensitive receptor that senses mechanical forces generated by fluid shear stress (By similarity)., [UniProtKB, UniProtKB]; Key negative regulator of Shh signaling, which promotes the processing of GLI3 into GLI3R during neural tube development. Recruited by TULP3 and the IFT-A complex to primary cilia and acts as a regulator of the PKA-dependent basal repression machinery in Shh signaling by increasing cAMP levels, leading to promote the PKA-dependent processing of GLI3 into GLI3R and repress the Shh signaling. In presence of SHH, it is removed from primary cilia and is internalized into recycling endosomes, preventing its activity and allowing activation of the Shh signaling. Its ligand is unknown., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "F1MSH4", "ec_number_list": "", "go_molecular_function": "GO:0004930 G protein-coupled receptor activity", "go_cellular_component": "GO:0005929 cilium;GO:0055037 recycling endosome;GO:0060170 ciliary membrane", "go_biological_process": "GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q2YDN1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3T178-1", "uniprot_id": "VPS28_BOVIN", "mass": 25484.0, "length": 221, "protein_name": "Vacuolar protein sorting-associated protein 28 homolog", "gene_name": "VPS28", "organism": "Bovine", "refseq_name": "vacuolar protein sorting-associated protein 28 homolog", "refseq_ac": "NP_001030581", "gene_names_uniprotkb": "VPS28", "gene_names_refseq": "VPS28", "protein_names_uniprotkb": "Vacuolar protein sorting-associated protein 28 homolog; ESCRT-I complex subunit VPS28", "protein_names_refseq": "ESCRT-I complex subunit VPS28; VPS28, ESCRT-I subunit; vacuolar protein sorting 28 homolog; vacuolar protein sorting-associated protein 28 homolog", "tax_id": 9913, "disease": "", "pathway": " (bta:618785); (R-BTA-917729)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "30739790", "class_list": "", "function": "Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process., [UniProtKB, UniProtKB]; Component of the ESCRT-I complex, a regulator of vesicular trafficking process., [UniProtKB]; VPS28 knockdown increases the expression of ADFP and CD36, leads accumulation of ubiquitinated proteins, long chain fatty acids and triglyceride, and decreases proteasome activity., [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0044877 protein-containing complex binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0031902 late endosome membrane;GO:0000813 ESCRT I complex", "go_biological_process": "GO:0043328 protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway;GO:0031397 negative regulation of protein ubiquitination;GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway;GO:0015031 protein transport;GO:0032509 endosome transport via multivesicular body sorting pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q3T178-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3T0G1-1", "uniprot_id": "THAP1_BOVIN", "mass": 24876.0, "length": 213, "protein_name": "THAP domain-containing protein 1", "gene_name": "THAP1", "organism": "Bovine", "refseq_name": "THAP domain-containing protein 1", "refseq_ac": "NP_001029820", "gene_names_uniprotkb": "THAP1", "gene_names_refseq": "THAP1", "protein_names_uniprotkb": "THAP domain-containing protein 1", "protein_names_refseq": "THAP domain containing, apoptosis associated protein 1; THAP domain-containing protein 1", "tax_id": 9913, "disease": "", "pathway": " (bta:538615)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "DNA-binding transcription regulator that regulates endothelial cell proliferation and G1/S cell-cycle progression. Specifically binds the 5'-[AT]NTNN[GT]GGCA[AGT]-3' core DNA sequence and acts by modulating expression of pRB-E2F cell-cycle target genes., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0008270 zinc ion binding;GO:0042803 protein homodimerization activity;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0043565 sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0016605 PML body;GO:0005654 nucleoplasm", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0006355 regulation of DNA-templated transcription;GO:0007346 regulation of mitotic cell cycle;GO:0001935 endothelial cell proliferation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q3T0G1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3T0R1-1", "uniprot_id": "RS18_BOVIN", "mass": 17719.0, "length": 152, "protein_name": "Small ribosomal subunit protein uS13", "gene_name": "RPS18", "organism": "Bovine", "refseq_name": "small ribosomal subunit protein uS13", "refseq_ac": "NP_001028786", "gene_names_uniprotkb": "RPS18", "gene_names_refseq": "RPS18", "protein_names_uniprotkb": "Small ribosomal subunit protein uS13; 40S ribosomal protein S18", "protein_names_refseq": "40S ribosomal protein S18; small ribosomal subunit protein uS13", "tax_id": 9913, "disease": "", "pathway": " (bta:326602); (R-BTA-156827); (R-BTA-1799339); (R-BTA-6791226); (R-BTA-72649); (R-BTA-72689); (R-BTA-72695); (R-BTA-72702); (R-BTA-72706); (R-BTA-975956); (R-BTA-975957); (R-BTA-9954714); (R-BTA-9954716)", "pathway_count": 13, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of the small ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0019843 rRNA binding;GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005829 cytosol;GO:0015935 small ribosomal subunit;GO:0022627 cytosolic small ribosomal subunit;GO:0022626 cytosolic ribosome;GO:1990904 ribonucleoprotein complex", "go_biological_process": "GO:0006412 translation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q3T0R1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2NKU0-1", "uniprot_id": "CENPX_BOVIN", "mass": 8879.0, "length": 79, "protein_name": "Centromere protein X", "gene_name": "CENPX", "organism": "Bovine", "refseq_name": "centromere protein X", "refseq_ac": "NP_001107999", "gene_names_uniprotkb": "CENPX; FAAP10; MHF2; STRA13", "gene_names_refseq": "BHLHB2; CENPX; STRA13", "protein_names_uniprotkb": "Centromere protein X; CENP-X; FANCM-interacting histone fold protein 2; Fanconi anemia-associated polypeptide of 10 kDa; Stimulated by retinoic acid gene 13 protein homolog", "protein_names_refseq": "CENP-X; FANCM-interacting histone fold protein 2; Fanconi anemia-associated polypeptide of 10 kDa; basic helix-loop-helix domain containing, class B, 2; centromere protein X; stimulated by retinoic acid gene 13 protein homolog", "tax_id": 9913, "disease": "", "pathway": " (bta:618018); (R-BTA-606279); (R-BTA-6783310); (R-BTA-9833482)", "pathway_count": 4, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "DNA-binding component of the Fanconi anemia (FA) core complex. Required for the normal activation of the FA pathway, leading to monoubiquitination of the FANCI-FANCD2 complex in response to DNA damage, cellular resistance to DNA cross-linking drugs, and prevention of chromosomal breakage. In complex with CENPS (MHF heterodimer), crucial cofactor for FANCM in both binding and ATP-dependent remodeling of DNA. Stabilizes FANCM. In complex with CENPS and FANCM (but not other FANC proteins), rapidly recruited to blocked forks and promotes gene conversion at blocked replication forks. In complex with CENPS, CENPT and CENPW (CENP-T-W-S-X heterotetramer), involved in the formation of a functional kinetochore outer plate, which is essential for kinetochore-microtubule attachment and faithful mitotic progression. As a component of MHF and CENP-T-W-S-X complexes, binds DNA and bends it to form a nucleosome-like structure. DNA-binding function is fulfilled in the presence of CENPS, with the following preference for DNA substates: Holliday junction > double-stranded > splay arm > single-stranded. Does not bind DNA on its own., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003690 double-stranded DNA binding", "go_cellular_component": "GO:0043240 Fanconi anaemia nuclear complex;GO:0071821 FANCM-MHF complex;GO:0000776 kinetochore;GO:0000785 chromatin", "go_biological_process": "GO:0000712 resolution of meiotic recombination intermediates;GO:0051382 kinetochore assembly;GO:0051301 cell division;GO:0036297 interstrand cross-link repair;GO:0031297 replication fork processing", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2NKU0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3T0Q2-1", "uniprot_id": "TMM59_BOVIN", "mass": 36065.0, "length": 323, "protein_name": "Transmembrane protein 59", "gene_name": "TMEM59", "organism": "Bovine", "refseq_name": "transmembrane protein 59 precursor", "refseq_ac": "NP_001030248", "gene_names_uniprotkb": "TMEM59", "gene_names_refseq": "TMEM59", "protein_names_uniprotkb": "Transmembrane protein 59", "protein_names_refseq": "transmembrane protein 59 precursor", "tax_id": 9913, "disease": "", "pathway": " (bta:509775); (R-BTA-9013407); (R-BTA-9696273)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "19393038", "class_list": "", "function": "Acts as a regulator of autophagy in response to S.aureus infection by promoting activation of LC3 (MAP1LC3A, MAP1LC3B or MAP1LC3C). Acts by interacting with ATG16L1, leading to promote a functional complex between LC3 and ATG16L1 and promoting LC3 lipidation and subsequent activation of autophagy. Modulates the O-glycosylation and complex N-glycosylation steps occurring during the Golgi maturation of several proteins such as APP, BACE1, SEAP or PRNP. Inhibits APP transport to the cell surface and further shedding., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "F1MBR3", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005886 plasma membrane;GO:0005764 lysosome;GO:0005765 lysosomal membrane;GO:0031902 late endosome membrane", "go_biological_process": "GO:0006914 autophagy;GO:0010508 positive regulation of autophagy", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q3T0Q2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q32PA0-1", "uniprot_id": "RU1C_BOVIN", "mass": 17394.0, "length": 159, "protein_name": "U1 small nuclear ribonucleoprotein C", "gene_name": "SNRPC", "organism": "Bovine", "refseq_name": "U1 small nuclear ribonucleoprotein C", "refseq_ac": "NP_001069802", "gene_names_uniprotkb": "SNRPC", "gene_names_refseq": "SNRPC; U1C", "protein_names_uniprotkb": "U1 small nuclear ribonucleoprotein C; U1 snRNP C; U1-C; U1C", "protein_names_refseq": "U1 small nuclear ribonucleoprotein C; U1 snRNP C; U1 snRNP protein C; U1-C", "tax_id": 9913, "disease": "", "pathway": " (bta:614553); (R-BTA-72163); (R-BTA-9770562)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region., [UniProtKB, HAMAP, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "F1MM98", "ec_number_list": "", "go_molecular_function": "GO:0030627 pre-mRNA 5'-splice site binding;GO:0003729 mRNA binding;GO:0008270 zinc ion binding;GO:0030619 U1 snRNA binding", "go_cellular_component": "GO:0005685 U1 snRNP;GO:0000243 commitment complex;GO:0071004 U2-type prespliceosome", "go_biological_process": "GO:0000387 spliceosomal snRNP assembly;GO:0000395 mRNA 5'-splice site recognition", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q32PA0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q32KX7-1", "uniprot_id": "BMI1_BOVIN", "mass": 36966.0, "length": 326, "protein_name": "Polycomb complex protein BMI-1", "gene_name": "BMI1", "organism": "Bovine", "refseq_name": "polycomb complex protein BMI-1", "refseq_ac": "NP_001033161", "gene_names_uniprotkb": "BMI1; PCGF4", "gene_names_refseq": "BMI1; PCGF4", "protein_names_uniprotkb": "Polycomb complex protein BMI-1; Polycomb group RING finger protein 4", "protein_names_refseq": "BMI1 polycomb ring finger oncogene; polycomb complex protein BMI-1; polycomb group RING finger protein 4; polycomb group ring finger 4", "tax_id": 9913, "disease": "", "pathway": " (bta:510666); (R-BTA-2559580); (R-BTA-3108214); (R-BTA-3899300); (R-BTA-4551638); (R-BTA-4570464); (R-BTA-8939243); (R-BTA-8943724); (R-BTA-8953750)", "pathway_count": 9, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. The complex composed of RNF2, UB2D3 and BMI1 binds nucleosomes, and has activity only with nucleosomal histone H2A. In the PRC1-like complex, regulates the E3 ubiquitin-protein ligase activity of RNF2/RING2., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0097027 ubiquitin-protein transferase activator activity;GO:0071535 RING-like zinc finger domain binding;GO:1990841 promoter-specific chromatin binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0016604 nuclear body;GO:0000151 ubiquitin ligase complex;GO:0000792 heterochromatin;GO:0031519 PcG protein complex", "go_biological_process": "GO:0033092 positive regulation of immature T cell proliferation in thymus;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006338 chromatin remodeling;GO:0006351 DNA-templated transcription;GO:0030890 positive regulation of B cell proliferation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q32KX7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3SZC6-1", "uniprot_id": "AN32B_BOVIN", "mass": 29872.0, "length": 261, "protein_name": "Acidic leucine-rich nuclear phosphoprotein 32 family member B", "gene_name": "ANP32B", "organism": "Bovine", "refseq_name": "acidic leucine-rich nuclear phosphoprotein 32 family member B", "refseq_ac": "NP_001030246", "gene_names_uniprotkb": "ANP32B", "gene_names_refseq": "ANP32B", "protein_names_uniprotkb": "Acidic leucine-rich nuclear phosphoprotein 32 family member B", "protein_names_refseq": "acidic (leucine-rich) nuclear phosphoprotein 32 family, member B; acidic leucine-rich nuclear phosphoprotein 32 family member B", "tax_id": 9913, "disease": "", "pathway": " (bta:509685)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Multifunctional protein that is involved in the regulation of many processes including cell proliferation, apoptosis, cell cycle progression or transcription. Regulates the proliferation of neuronal stem cells, differentiation of leukemic cells and progression from G1 to S phase of the cell cycle. As negative regulator of caspase-3-dependent apoptosis, may act as an antagonist of ANP32A in regulating tissue homeostasis. Exhibits histone chaperone properties, able to recruit histones to certain promoters, thus regulating the transcription of specific genes. Also plays an essential role in the nucleocytoplasmic transport of specific mRNAs via the uncommon nuclear mRNA export receptor XPO1/CRM1 (By similarity). Participates in the regulation of adequate adaptive immune responses by acting on mRNA expression and cell proliferation (By similarity)., [UniProtKB, UniProtKB, UniProtKB]; Multifunctional protein that is involved in the regulation of many processes., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0042393 histone binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005783 endoplasmic reticulum;GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "GO:0006913 nucleocytoplasmic transport;GO:0042981 regulation of apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q3SZC6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2TBH8-1", "uniprot_id": "ZWINT_BOVIN", "mass": 32614.0, "length": 286, "protein_name": "Outer kinetochore KNL1 complex subunit ZWINT", "gene_name": "ZWINT", "organism": "Bovine", "refseq_name": "outer kinetochore KNL1 complex subunit ZWINT", "refseq_ac": "NP_001035619", "gene_names_uniprotkb": "ZWINT", "gene_names_refseq": "ZWINT", "protein_names_uniprotkb": "Outer kinetochore KNL1 complex subunit ZWINT; ZW10 interactor; ZW10-interacting protein 1; Zwint-1", "protein_names_refseq": "ZW10 interactor; ZW10-interacting protein 1; outer kinetochore KNL1 complex subunit ZWINT; zwint-1", "tax_id": 9913, "disease": "", "pathway": " (bta:514564)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Acts as a component of the outer kinetochore KNL1 complex that serves as a docking point for spindle assembly checkpoint components and mediates microtubule-kinetochore interactions. Kinetochores, consisting of a centromere-associated inner segment and a microtubule-contacting outer segment, play a crucial role in chromosome segregation by mediating the physical connection between centromeric DNA and spindle microtubules. The outer kinetochore is made up of the ten-subunit KMN network, comprising the MIS12, NDC80 and KNL1 complexes, and auxiliary microtubule-associated components; together they connect the outer kinetochore with the inner kinetochore, bind microtubules, and mediate interactions with mitotic checkpoint proteins that delay anaphase until chromosomes are bioriented on the spindle. Targets the RZZ complex to the kinetochore at prometaphase (By similarity). Recruits MAD2L1 to the kinetochore, but is not required for BUB1B localization. In addition to orienting mitotic chromosomes, it is also essential for alignment of homologous chromosomes during meiotic metaphase I. In meiosis I, required to activate the spindle assembly checkpoint at unattached kinetochores to correct erroneous kinetochore-microtubule attachments (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "F1N7G9", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005829 cytosol;GO:0030425 dendrite;GO:0016604 nuclear body;GO:0000776 kinetochore;GO:0180019 Knl1/Spc105 complex", "go_biological_process": "GO:0031619 homologous chromosome orientation in meiotic metaphase I;GO:0051301 cell division;GO:0007094 mitotic spindle assembly checkpoint signaling;GO:0051649 establishment of localization in cell;GO:0000070 mitotic sister chromatid segregation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2TBH8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q32L35-1", "uniprot_id": "MIC25_BOVIN", "mass": 26439.0, "length": 236, "protein_name": "MICOS complex subunit MIC25", "gene_name": "CHCHD6", "organism": "Bovine", "refseq_name": "MICOS complex subunit MIC25", "refseq_ac": "NP_001069870", "gene_names_uniprotkb": "CHCHD6; MIC25", "gene_names_refseq": "CHCHD6", "protein_names_uniprotkb": "MICOS complex subunit MIC25; Coiled-coil-helix-coiled-coil-helix domain-containing protein 6", "protein_names_refseq": "MICOS complex subunit MIC25; coiled-coil-helix-coiled-coil-helix domain-containing protein 6, mitochondrial", "tax_id": 9913, "disease": "", "pathway": " (bta:615934)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "19393038", "class_list": "", "function": "Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane;GO:0061617 MICOS complex", "go_biological_process": "GO:0006974 DNA damage response;GO:0042407 cristae formation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q32L35-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q32KS0-1", "uniprot_id": "TBCE_BOVIN", "mass": 59327.0, "length": 528, "protein_name": "Tubulin-specific chaperone E", "gene_name": "TBCE", "organism": "Bovine", "refseq_name": "tubulin-specific chaperone E", "refseq_ac": "NP_001033121", "gene_names_uniprotkb": "TBCE", "gene_names_refseq": "TBCE", "protein_names_uniprotkb": "Tubulin-specific chaperone E; Tubulin-folding cofactor E", "protein_names_refseq": "beta-tubulin cofactor E; tubulin-specific chaperone E", "tax_id": 9913, "disease": "", "pathway": " (bta:505066)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "16305752", "class_list": "", "function": "Tubulin-folding protein; involved in the second step of the tubulin folding pathway and in the regulation of tubulin heterodimer dissociation. Required for correct organization of microtubule cytoskeleton and mitotic splindle, and maintenance of the neuronal microtubule network., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q0V8R2", "ec_number_list": "", "go_molecular_function": "GO:0043014 alpha-tubulin binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005856 cytoskeleton", "go_biological_process": "GO:0000226 microtubule cytoskeleton organization;GO:0007021 tubulin complex assembly;GO:0007052 mitotic spindle organization;GO:0007023 post-chaperonin tubulin folding pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q32KS0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2TBR0-1", "uniprot_id": "PCCB_BOVIN", "mass": 58311.0, "length": 539, "protein_name": "Propionyl-CoA carboxylase beta chain, mitochondrial", "gene_name": "PCCB", "organism": "Bovine", "refseq_name": "propionyl-CoA carboxylase beta chain, mitochondrial precursor", "refseq_ac": "NP_001033637", "gene_names_uniprotkb": "PCCB", "gene_names_refseq": "PCCB", "protein_names_uniprotkb": "Propionyl-CoA carboxylase beta chain, mitochondrial; 6.4.1.3; PCCase subunit beta; Propanoyl-CoA:carbon dioxide ligase subunit beta", "protein_names_refseq": "PCCase beta subunit; PCCase subunit beta; propanoyl-CoA:carbon dioxide ligase beta subunit; propanoyl-CoA:carbon dioxide ligase subunit beta; propionyl CoA carboxylase, beta polypeptide; propionyl Coenzyme A carboxylase, beta polypeptide; propionyl-CoA carboxylase beta chain, mitochondrial precursor; propionyl-CoA carboxylase beta chain, mitochondrial; propionyl-CoA carboxylase beta subunit", "tax_id": 9913, "disease": "", "pathway": " (bta:515902); (R-BTA-196780); (R-BTA-71032); (R-BTA-9837999)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "14398975", "class_list": "", "function": "This is one of the 2 subunits of the biotin-dependent propionyl-CoA carboxylase (PCC), a mitochondrial enzyme involved in the catabolism of odd chain fatty acids, branched-chain amino acids isoleucine, threonine, methionine, and valine and other metabolites. Propionyl-CoA carboxylase catalyzes the carboxylation of propionyl-CoA/propanoyl-CoA to D-methylmalonyl-CoA/(S)-methylmalonyl-CoA (By similarity). Within the holoenzyme, the alpha subunit catalyzes the ATP-dependent carboxylation of the biotin carried by the biotin carboxyl carrier (BCC) domain, while the beta subunit then transfers the carboxyl group from carboxylated biotin to propionyl-CoA (By similarity). Propionyl-CoA carboxylase also significantly acts on butyryl-CoA/butanoyl-CoA, which is converted to ethylmalonyl-CoA/(2S)-ethylmalonyl-CoA (By similarity). Other alternative minor substrates include (2E)-butenoyl-CoA/crotonoyl-CoA (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.4.1.3;2.7.1.23;6.4.1.4;1.1.1.35;5.3.3.21;6.4.1.3;2.7.11.-;3.4.21.53;5.3.3.8;2.3.1.41;6.1.1.5;3.5.3.1;5.6.1.7;1.1.1.62;1.1.1.239;1.1.1.178;1.1.1.53;1.1.1.159;7.1.2.2;2.3.1.168;2.3.1.-;1.2.4.1;7.1.1.2;1.2.1.3;4.2.1.3;4.98.1.1;1.3.8.5;1.2.4.2;2.3.3.1;6.4.1.1;2.3.1.9;2.3.3.10;1.1.1.37;3.6.4.10;1.3.8.1", "go_molecular_function": "GO:0005524 ATP binding;GO:0004658 propionyl-CoA carboxylase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0009062 fatty acid catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q2TBR0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3SWX8-1", "uniprot_id": "RBBP7_BOVIN", "mass": 47844.0, "length": 425, "protein_name": "Histone-binding protein RBBP7", "gene_name": "RBBP7", "organism": "Bovine", "refseq_name": "histone-binding protein RBBP7", "refseq_ac": "NP_001029810", "gene_names_uniprotkb": "RBBP7", "gene_names_refseq": "RBBP7", "protein_names_uniprotkb": "Histone-binding protein RBBP7; Nucleosome-remodeling factor subunit RBAP46; RBBP-7; Retinoblastoma-binding protein 7", "protein_names_refseq": "RBBP-7; histone-binding protein RBBP7; nucleosome-remodeling factor subunit RBAP46; retinoblastoma binding protein 7", "tax_id": 9913, "disease": "", "pathway": " (bta:537402); (R-BTA-212300); (R-BTA-2559580); (R-BTA-3214815); (R-BTA-3214841); (R-BTA-3214847); (R-BTA-3214858); (R-BTA-606279); (R-BTA-6804758); (R-BTA-73762); (R-BTA-8943724); (R-BTA-8951664); (R-BTA-8953750); (R-BTA-9764725); (R-BTA-9909649); (R-BTA-9937850); (R-BTA-9940951)", "pathway_count": 17, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Core histone-binding subunit that may target chromatin remodeling factors, histone acetyltransferases and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the type B histone acetyltransferase (HAT) complex, which is required for chromatin assembly following DNA replication; the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression; the nucleosome remodeling and histone deacetylase complex (the NuRD complex), which promotes transcriptional repression by histone deacetylation and nucleosome remodeling; and the PRC2/EED-EZH2 complex, which promotes repression of homeotic genes during development; and the NURF (nucleosome remodeling factor) complex (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0042393 histone binding;GO:0003723 RNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0035098 ESC/E(Z) complex;GO:0016581 NuRD complex;GO:0000781 chromosome, telomeric region", "go_biological_process": "GO:0006338 chromatin remodeling;GO:0006351 DNA-templated transcription;GO:0006355 regulation of DNA-templated transcription;GO:0006260 DNA replication;GO:0030308 negative regulation of cell growth", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q3SWX8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3SZY9-1", "uniprot_id": "MED6_BOVIN", "mass": 28406.0, "length": 246, "protein_name": "Mediator of RNA polymerase II transcription subunit 6", "gene_name": "MED6", "organism": "Bovine", "refseq_name": "mediator of RNA polymerase II transcription subunit 6", "refseq_ac": "NP_001029409", "gene_names_uniprotkb": "MED6", "gene_names_refseq": "MED6", "protein_names_uniprotkb": "Mediator of RNA polymerase II transcription subunit 6; Mediator complex subunit 6", "protein_names_refseq": "mediator of RNA polymerase II transcription subunit 6; mediator of RNA polymerase II transcription, subunit 6 homolog", "tax_id": 9913, "disease": "", "pathway": " (bta:505293); (R-BTA-212436); (R-BTA-9841922)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003713 transcription coactivator activity;GO:0003712 transcription coregulator activity;GO:0003677 DNA binding;GO:0001223 transcription coactivator binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0016592 mediator complex;GO:0070847 core mediator complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q3SZY9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3SZL8-1", "uniprot_id": "CNDH2_BOVIN", "mass": 69775.0, "length": 622, "protein_name": "Condensin-2 complex subunit H2", "gene_name": "NCAPH2", "organism": "Bovine", "refseq_name": "condensin-2 complex subunit H2", "refseq_ac": "NP_001070511", "gene_names_uniprotkb": "NCAPH2", "gene_names_refseq": "NCAPH2", "protein_names_uniprotkb": "Condensin-2 complex subunit H2; Non-SMC condensin II complex subunit H2", "protein_names_refseq": "condensin-2 complex subunit H2", "tax_id": 9913, "disease": "", "pathway": " (bta:767978); (R-BTA-2299718)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Regulatory subunit of the condensin-2 complex, a complex that seems to provide chromosomes with an additional level of organization and rigidity and in establishing mitotic chromosome architecture (By similarity). May promote the resolution of double-strand DNA catenanes (intertwines) between sister chromatids. Condensin-mediated compaction likely increases tension in catenated sister chromatids, providing directionality for type II topoisomerase-mediated strand exchanges toward chromatid decatenation. Required for decatenation of chromatin bridges at anaphase. Early in neurogenesis, may play an essential role to ensure accurate mitotic chromosome condensation in neuron stem cells, ultimately affecting neuron pool and cortex size (By similarity). Seems to have lineage-specific role in T-cell development (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003682 chromatin binding", "go_cellular_component": "GO:0000794 condensed nuclear chromosome;GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0000796 condensin complex", "go_biological_process": "GO:1905820 positive regulation of chromosome separation;GO:0051984 positive regulation of chromosome segregation;GO:0021987 cerebral cortex development;GO:0007076 mitotic chromosome condensation;GO:0051306 mitotic sister chromatid separation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q3SZL8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3MHY6-1", "uniprot_id": "NUBP2_BOVIN", "mass": 28789.0, "length": 271, "protein_name": "Cytosolic Fe-S cluster assembly factor NUBP2", "gene_name": "NUBP2", "organism": "Bovine", "refseq_name": "cytosolic Fe-S cluster assembly factor NUBP2", "refseq_ac": "NP_001029677", "gene_names_uniprotkb": "NUBP2", "gene_names_refseq": "NUBP2", "protein_names_uniprotkb": "Cytosolic Fe-S cluster assembly factor NUBP2; NBP 2; Nucleotide-binding protein 2", "protein_names_refseq": "NBP 2; cytosolic Fe-S cluster assembly factor NUBP2; nucleotide binding protein 2 (MinD homolog, E. coli); nucleotide-binding protein 2", "tax_id": 9913, "disease": "", "pathway": " (bta:515660)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins. Negatively regulates cilium formation and structure., [UniProtKB, HAMAP, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0051539 4 iron, 4 sulfur cluster binding;GO:0051536 iron-sulfur cluster binding;GO:0140663 ATP-dependent FeS chaperone activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005813 centrosome;GO:0005829 cytosol;GO:0005814 centriole;GO:0005930 axoneme", "go_biological_process": "GO:0016226 iron-sulfur cluster assembly;GO:0030030 cell projection organization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q3MHY6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3SYW6-1", "uniprot_id": "EIF3C_BOVIN", "mass": 105366.0, "length": 912, "protein_name": "Eukaryotic translation initiation factor 3 subunit C", "gene_name": "EIF3CL; EIF3C", "organism": "Bovine", "refseq_name": "eukaryotic translation initiation factor 3 subunit C", "refseq_ac": "NP_001029790", "gene_names_uniprotkb": "EIF3CL; EIF3C; EIF3C; EIF3S8", "gene_names_refseq": "EIF3CL; EIF3C; EIF3S8; eIF3-p110", "protein_names_uniprotkb": "Eukaryotic translation initiation factor 3 subunit C; Eukaryotic translation initiation factor 3 subunit 8; eIF3 p110; eIF3c", "protein_names_refseq": "eIF3 p110; eukaryotic translation initiation factor 3 subunit 8; eukaryotic translation initiation factor 3 subunit C; eukaryotic translation initiation factor 3, subunit 8, 110kDa; eukaryotic translation initiation factor 3, subunit C", "tax_id": 9913, "disease": "", "pathway": " (bta:534882); (R-BTA-156827); (R-BTA-72649); (R-BTA-72689); (R-BTA-72695); (R-BTA-72702)", "pathway_count": 6, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression., [UniProtKB, HAMAP, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 13, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding;GO:0003743 translation initiation factor activity;GO:0031369 translation initiation factor binding", "go_cellular_component": "GO:0005829 cytosol;GO:0016282 eukaryotic 43S preinitiation complex;GO:0033290 eukaryotic 48S preinitiation complex;GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m;GO:0005852 eukaryotic translation initiation factor 3 complex", "go_biological_process": "GO:0006413 translational initiation;GO:0001732 formation of cytoplasmic translation initiation complex", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q3SYW6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2TLZ3-1", "uniprot_id": "MACOI_BOVIN", "mass": 76118.0, "length": 664, "protein_name": "Macoilin", "gene_name": "MACO1", "organism": "Bovine", "refseq_name": "macoilin", "refseq_ac": "NP_001033736", "gene_names_uniprotkb": "MACO1; TMEM57", "gene_names_refseq": "MACO1; TMEM57", "protein_names_uniprotkb": "Macoilin; Transmembrane protein 57", "protein_names_refseq": "macoilin; transmembrane protein 57", "tax_id": 9913, "disease": "", "pathway": " (bta:540726)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Plays a role in the regulation of neuronal activity., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 4, "predicted_n_glycosites": 4, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0031965 nuclear membrane;GO:0030867 rough endoplasmic reticulum membrane;GO:0030424 axon;GO:0045202 synapse;GO:0044306 neuron projection terminus", "go_biological_process": "GO:0023041 neuronal signal transduction;GO:0007420 brain development", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2TLZ3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q32LM0-1", "uniprot_id": "SHLB1_BOVIN", "mass": 40777.0, "length": 365, "protein_name": "Endophilin-B1", "gene_name": "SH3GLB1", "organism": "Bovine", "refseq_name": "endophilin-B1", "refseq_ac": "NP_001071461", "gene_names_uniprotkb": "SH3GLB1", "gene_names_refseq": "SH3GLB1", "protein_names_uniprotkb": "Endophilin-B1; SH3 domain-containing GRB2-like protein B1", "protein_names_refseq": "SH3 domain GRB2-like protein B1; SH3 domain-containing GRB2-like protein B1; endophilin-B1", "tax_id": 9913, "disease": "", "pathway": " (bta:533918)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "May be required for normal outer mitochondrial membrane dynamics. Required for coatomer-mediated retrograde transport in certain cells. May recruit other proteins to membranes with high curvature. May promote membrane fusion. Involved in activation of caspase-dependent apoptosis by promoting BAX/BAK1 activation. Involved in caspase-independent apoptosis during nutrition starvation and involved in the regulation of autophagy. Activates lipid kinase activity of PIK3C3 during autophagy probably by associating with the PI3K complex II (PI3KC3-C2). Associated with PI3KC3-C2 during autophagy may regulate the trafficking of ATG9A from the Golgi complex to the peripheral cytoplasm for the formation of autophagosomes by inducing Golgi membrane tubulation and fragmentation. Involved in regulation of degradative endocytic trafficking and cytokinesis, probably in the context of PI3KC3-C2 (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0030674 protein-macromolecule adaptor activity;GO:0008289 lipid binding;GO:0005504 fatty acid binding;GO:0042171 lysophosphatidic acid acyltransferase activity;GO:0042803 protein homodimerization activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0000421 autophagosome membrane;GO:0005741 mitochondrial outer membrane;GO:0016020 membrane;GO:0031410 cytoplasmic vesicle", "go_biological_process": "GO:0006897 endocytosis;GO:0006915 apoptotic process;GO:0061024 membrane organization;GO:0031334 positive regulation of protein-containing complex assembly;GO:0042149 cellular response to glucose starvation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q32LM0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q32KR8-1", "uniprot_id": "ADPRH_BOVIN", "mass": 39152.0, "length": 353, "protein_name": "ADP-ribosylhydrolase ARH1", "gene_name": "ADPRH", "organism": "Bovine", "refseq_name": "ADP-ribosylhydrolase ARH1", "refseq_ac": "NP_001033643", "gene_names_uniprotkb": "ADPRH; ARH1", "gene_names_refseq": "ADPRH", "protein_names_uniprotkb": "ADP-ribosylhydrolase ARH1; 3.2.2.19; ADP-ribose-L-arginine cleaving enzyme; ADP-ribosylarginine hydrolase; [Protein ADP-ribosylarginine] hydrolase", "protein_names_refseq": "ADP-ribose-L-arginine cleaving enzyme; ADP-ribosylhydrolase ARH1; [Protein ADP-ribosylarginine] hydrolase", "tax_id": 9913, "disease": "", "pathway": " (bta:525738)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Hydrolyzes the ester bond of the acyl group attached at the sn-1 position of phosphatidylserines (phospholipase A1 activity) and 1-acyl-2-lysophosphatidylserines (lysophospholipase activity) in the pathway of phosphatidylserines acyl chain remodeling. Cleaves phosphatidylserines exposed on the outer leaflet of the plasma membrane of apoptotic cells producing 2-acyl-1-lysophosphatidylserines, which in turn enhance mast cell activation and histamine production. Has no activity toward other glycerophospholipids including phosphatidylcholines, phosphatidylethanolamines, phosphatidic acids or phosphatidylinositols, or glycerolipids such as triolein., [UniProtKB, UniProtKB]; Specifically acts as an arginine mono-ADP-ribosylhydrolase by mediating the removal of mono-ADP-ribose attached to arginine residues on proteins., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.2.1.143;3.1.1.32;3.1.1.111;3.1.1.118;3.1.1.-;3.1.1.23;3.1.-.-;3.5.1.-;3.2.2.-;3.1.1.106;3.2.2.19;3.1.1.3;3.1.1.5", "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0003875 ADP-ribosylarginine hydrolase activity;GO:0030955 potassium ion binding;GO:0046872 metal ion binding;GO:0008970 phospholipase A1 activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0002080 acrosomal membrane", "go_biological_process": "GO:0036211 protein modification process;GO:0051725 protein de-ADP-ribosylation;GO:0016042 lipid catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q32KR8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2YDE3-1", "uniprot_id": "GOT1B_BOVIN", "mass": 15426.0, "length": 138, "protein_name": "Vesicle transport protein GOT1B", "gene_name": "GOLT1B", "organism": "Bovine", "refseq_name": "vesicle transport protein GOT1B", "refseq_ac": "NP_001039680", "gene_names_uniprotkb": "GOLT1B", "gene_names_refseq": "GOLT1B", "protein_names_uniprotkb": "Vesicle transport protein GOT1B; Golgi transport 1 homolog B", "protein_names_refseq": "vesicle transport protein GOT1B", "tax_id": 9913, "disease": "", "pathway": " (bta:515866)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "May be involved in fusion of ER-derived transport vesicles with the Golgi complex., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005783 endoplasmic reticulum;GO:0005829 cytosol;GO:0016020 membrane;GO:0032991 protein-containing complex", "go_biological_process": "GO:0015031 protein transport;GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0042147 retrograde transport, endosome to Golgi", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2YDE3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3MHP8-1", "uniprot_id": "BET1L_BOVIN", "mass": 12320.0, "length": 111, "protein_name": "BET1-like protein", "gene_name": "BET1L", "organism": "Bovine", "refseq_name": "BET1-like protein", "refseq_ac": "NP_001029534", "gene_names_uniprotkb": "BET1L", "gene_names_refseq": "BET1L", "protein_names_uniprotkb": "BET1-like protein", "protein_names_refseq": "BET1-like protein; blocked early in transport 1 homolog-like", "tax_id": 9913, "disease": "", "pathway": " (bta:509758); (R-BTA-6807878); (R-BTA-6811438)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Vesicle SNARE required for targeting and fusion of retrograde transport vesicles with the Golgi complex. Required for the integrity of the Golgi complex (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005484 SNAP receptor activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005768 endosome;GO:0005829 cytosol;GO:0005795 Golgi stack;GO:0031201 SNARE complex", "go_biological_process": "GO:0015031 protein transport;GO:0042147 retrograde transport, endosome to Golgi;GO:2000156 regulation of retrograde vesicle-mediated transport, Golgi to ER", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q3MHP8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q32L53-1", "uniprot_id": "LFG1_BOVIN", "mass": 40232.0, "length": 366, "protein_name": "Protein lifeguard 1", "gene_name": "GRINA", "organism": "Bovine", "refseq_name": "protein lifeguard 1", "refseq_ac": "NP_001032682", "gene_names_uniprotkb": "GRINA; LFG1; NMDARA1", "gene_names_refseq": "GRINA", "protein_names_uniprotkb": "Protein lifeguard 1; Glutamate [NMDA] receptor-associated protein 1; NMDA receptor glutamate-binding subunit", "protein_names_refseq": "NMDA receptor glutamate-binding subunit; glutamate [NMDA] receptor-associated protein 1; glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding); protein lifeguard 1", "tax_id": 9913, "disease": "", "pathway": " (bta:510225)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Potential apoptotic regulator., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005262 calcium channel activity;GO:0044325 transmembrane transporter binding", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0016020 membrane;GO:0000139 Golgi membrane", "go_biological_process": "GO:0043524 negative regulation of neuron apoptotic process;GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q32L53-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q32KP0-1", "uniprot_id": "SMIP6_BOVIN", "mass": 35066.0, "length": 304, "protein_name": "Sperm microtubule inner protein 6", "gene_name": "MYORG; SPMIP6", "organism": "Bovine", "refseq_name": "sperm microtubule inner protein 6", "refseq_ac": "NP_001069708", "gene_names_uniprotkb": "MYORG; SPMIP6; CBE1; SMRP1", "gene_names_refseq": "SMRP1; SPMIP6", "protein_names_uniprotkb": "Sperm microtubule inner protein 6; Ciliated bronchial epithelial protein 1; Spermatid-specific manchette-related protein 1; Testis development protein NYD-SP22", "protein_names_refseq": "ciliated bronchial epithelial protein 1; myogenesis regulating glycosidase (putative); sperm microtubule inner protein 6; spermatid-specific manchette-related protein 1; testes development-related NYD-SP22; testis development protein NYD-SP22", "tax_id": 9913, "disease": "", "pathway": " (bta:115945148); (bta:540767)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "37327785", "class_list": "", "function": "Alpha-galactosidase with unusual specificity for the Gal-alpha1,4-Glc structure, whose in vivo substrate is still unknown. Promotes myogenesis by activating AKT signaling through the maturation and secretion of IGF2., [UniProtKB, UniProtKB, UniProtKB]; May participate in intramanchette transport and midpiece formation of the sperm tail. May play a potential role in somatic cell proliferation., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0043014 alpha-tubulin binding;GO:0004557 alpha-galactosidase activity;GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0048471 perinuclear region of cytoplasm;GO:0002177 manchette", "go_biological_process": "GO:0007283 spermatogenesis;GO:0030154 cell differentiation;GO:0005975 carbohydrate metabolic process;GO:0048741 skeletal muscle fiber development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q32KP0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q32PJ7-1", "uniprot_id": "TENS4_BOVIN", "mass": 75846.0, "length": 716, "protein_name": "Tensin-4", "gene_name": "TNS4", "organism": "Bovine", "refseq_name": "tensin-4", "refseq_ac": "NP_001033244", "gene_names_uniprotkb": "TNS4", "gene_names_refseq": "TNS4", "protein_names_uniprotkb": "Tensin-4", "protein_names_refseq": "tensin-4", "tax_id": 9913, "disease": "", "pathway": " (bta:532898); (R-BTA-8875513)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "12140684", "class_list": "", "function": "Promotes EGF-induced cell migration by displacing tensin TNS3 from the cytoplasmic tail of integrin ITGB1 which results in dissociation of TNS3 from focal adhesions, disassembly of actin stress fibers and initiation of cell migration. Suppresses ligand-induced degradation of EGFR by reducing EGFR ubiquitination in the presence of EGF. Increases MET protein stability by inhibiting MET endocytosis and subsequent lysosomal degradation which leads to increased cell survival, proliferation and migration., [UniProtKB, UniProtKB]", "predicted_glycosites": 4, "predicted_n_glycosites": 0, "predicted_o_glycosites": 4, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "F1MN94", "ec_number_list": "", "go_molecular_function": "GO:0003779 actin binding", "go_cellular_component": "GO:0005829 cytosol;GO:0005856 cytoskeleton;GO:0005925 focal adhesion", "go_biological_process": "GO:0008104 intracellular protein localization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q32PJ7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3T0C7-1", "uniprot_id": "STMN1_BOVIN", "mass": 17303.0, "length": 149, "protein_name": "Stathmin", "gene_name": "STMN1", "organism": "Bovine", "refseq_name": "stathmin", "refseq_ac": "NP_001029962", "gene_names_uniprotkb": "STMN1", "gene_names_refseq": "STMN1", "protein_names_uniprotkb": "Stathmin", "protein_names_refseq": "stathmin 1/oncoprotein 18; stathmin", "tax_id": 9913, "disease": "", "pathway": " (bta:616317)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Involved in the regulation of the microtubule (MT) filament system by destabilizing microtubules. Prevents assembly and promotes disassembly of microtubules (By similarity). Its phosphorylation at Ser-16 may be required for axon formation during neurogenesis. Involved in the control of the learned and innate fear (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0015631 tubulin binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005874 microtubule;GO:0043005 neuron projection", "go_biological_process": "GO:0031110 regulation of microtubule polymerization or depolymerization;GO:0031175 neuron projection development;GO:0007019 microtubule depolymerization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q3T0C7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3SWY1-1", "uniprot_id": "ARI5A_BOVIN", "mass": 64136.0, "length": 592, "protein_name": "AT-rich interactive domain-containing protein 5A", "gene_name": "ARID5A", "organism": "Bovine", "refseq_name": "AT-rich interactive domain-containing protein 5A", "refseq_ac": "NP_001030426", "gene_names_uniprotkb": "ARID5A", "gene_names_refseq": "ARID5A", "protein_names_uniprotkb": "AT-rich interactive domain-containing protein 5A; ARID domain-containing protein 5A", "protein_names_refseq": "ARID domain-containing protein 5A; AT rich interactive domain 5A (MRF1-like); AT-rich interactive domain-containing protein 5A", "tax_id": 9913, "disease": "", "pathway": " (bta:524118)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "DNA-binding protein that may regulate transcription and act as a repressor by binding to AT-rich stretches in the promoter region of target genes. May act as repressor and down-regulate enhancer-dependent gene expressison. May positively regulate chondrocyte-specific transcription such as of COL2A1 in collaboration with SOX9 and positively regulate histone H3 acetylation at chondrocyte-specific genes. May stimulate early-stage chondrocyte differentiation and inhibit later stage differention. Can repress ESR1-mediated transcriptional activation; proposed to act as corepressor for selective nuclear hormone receptors. As an RNA-binding protein, involved in the regulation of inflammatory response by stabilizing selective inflammation-related mRNAs, such as STAT3 and TBX21. Also stabilizes IL6 mRNA. Binds to stem loop structures located in the 3'UTRs of IL6, STAT3 and TBX21 mRNAs; at least for STAT3 prevents binding of ZC3H12A to the mRNA stem loop structure thus inhibiting its degradation activity. Contributes to elevated IL6 levels possibly implicated in autoimmunity processes. IL6-dependent stabilization of STAT3 mRNA may promote differentiation of naive CD4+ T-cells into T-helper Th17 cells. In CD4+ T-cells may also inhibit RORC-induced Th17 cell differentiation independently of IL6 signaling. Stabilization of TBX21 mRNA contributes to elevated interferon-gamma secretion in Th1 cells possibly implicated in the establishment of septic shock. Stabilizes TNFRSF4/OX40 mRNA by binding to the conserved stem loop structure in its 3'UTR; thereby competing with the mRNA-destabilizing functions of RC3H1 and endoribonuclease ZC3H12A (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0000976 transcription cis-regulatory region binding;GO:0035925 mRNA 3'-UTR AU-rich region binding;GO:0003677 DNA binding;GO:0042802 identical protein binding;GO:0003714 transcription corepressor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005730 nucleolus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0045087 innate immune response;GO:1905870 positive regulation of 3'-UTR-mediated mRNA stabilization;GO:0000122 negative regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q3SWY1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2YDH0-1", "uniprot_id": "MUC24_BOVIN", "mass": 20347.0, "length": 198, "protein_name": "Sialomucin core protein 24", "gene_name": "CD164", "organism": "Bovine", "refseq_name": "sialomucin core protein 24 precursor", "refseq_ac": "NP_001039506", "gene_names_uniprotkb": "CD164", "gene_names_refseq": "CD164", "protein_names_uniprotkb": "Sialomucin core protein 24; Endolyn; MUC-24", "protein_names_refseq": "CD164 molecule, sialomucin; MUC-24; endolyn; sialomucin core protein 24 precursor; sialomucin core protein 24", "tax_id": 9913, "disease": "", "pathway": " (bta:509820)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Sialomucin that may play a key role in hematopoiesis. May be involved in cell adhesion. Promotes myogenesis by enhancing CXCR4-dependent cell motility. Positively regulates myoblast migration and promotes myoblast fusion into myotubes (By similarity)., [UniProtKB]", "predicted_glycosites": 7, "predicted_n_glycosites": 7, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 7, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005768 endosome;GO:0005886 plasma membrane;GO:0005764 lysosome;GO:0005765 lysosomal membrane;GO:0010008 endosome membrane", "go_biological_process": "GO:0007155 cell adhesion;GO:0007517 muscle organ development", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2YDH0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2TBR6-1", "uniprot_id": "PFD4_BOVIN", "mass": 15328.0, "length": 134, "protein_name": "Prefoldin subunit 4", "gene_name": "PFDN4", "organism": "Bovine", "refseq_name": "prefoldin subunit 4", "refseq_ac": "NP_001033629", "gene_names_uniprotkb": "PFDN4", "gene_names_refseq": "PFDN4", "protein_names_uniprotkb": "Prefoldin subunit 4", "protein_names_refseq": "prefoldin subunit 4", "tax_id": 9913, "disease": "", "pathway": " (bta:514621)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0051082 unfolded protein binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005829 cytosol;GO:0016272 prefoldin complex", "go_biological_process": "GO:0006457 protein folding", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2TBR6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3SYT6-1", "uniprot_id": "CLGN_BOVIN", "mass": 69515.0, "length": 606, "protein_name": "Calmegin", "gene_name": "CLGN", "organism": "Bovine", "refseq_name": "calmegin precursor", "refseq_ac": "NP_001029377", "gene_names_uniprotkb": "CLGN", "gene_names_refseq": "CLGN", "protein_names_uniprotkb": "Calmegin", "protein_names_refseq": "calmegin precursor", "tax_id": 9913, "disease": "", "pathway": " (bta:504256)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Functions during spermatogenesis as a chaperone for a range of client proteins that are important for sperm adhesion onto the egg zona pellucida and for subsequent penetration of the zona pellucida. Required for normal sperm migration from the uterus into the oviduct. Required for normal male fertility. Binds calcium ions (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 7, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0051082 unfolded protein binding;GO:0005509 calcium ion binding;GO:0044183 protein folding chaperone", "go_cellular_component": "GO:0005635 nuclear envelope;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006457 protein folding;GO:0036503 ERAD pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q3SYT6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q32KY3-1", "uniprot_id": "MLF1_BOVIN", "mass": 31227.0, "length": 270, "protein_name": "Myeloid leukemia factor 1", "gene_name": "MLF1", "organism": "Bovine", "refseq_name": "myeloid leukemia factor 1", "refseq_ac": "NP_001033247", "gene_names_uniprotkb": "MLF1", "gene_names_refseq": "MLF1", "protein_names_uniprotkb": "Myeloid leukemia factor 1; Myelodysplasia-myeloid leukemia factor 1", "protein_names_refseq": "myelodysplasia-myeloid leukemia factor 1; myeloid leukemia factor 1", "tax_id": 9913, "disease": "", "pathway": " (bta:533379)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Involved in lineage commitment of primary hemopoietic progenitors by restricting erythroid formation and enhancing myeloid formation. Interferes with erythropoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels. Suppresses COP1 activity via CSN3 which activates p53 and induces cell cycle arrest. Binds DNA and affects the expression of a number of genes so may function as a transcription factor in the nucleus (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005929 cilium;GO:0036064 ciliary basal body;GO:0031514 motile cilium", "go_biological_process": "GO:0002318 myeloid progenitor cell differentiation;GO:0006351 DNA-templated transcription;GO:0006355 regulation of DNA-templated transcription;GO:1902806 regulation of cell cycle G1/S phase transition", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q32KY3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3T191-1", "uniprot_id": "CIDEB_BOVIN", "mass": 24650.0, "length": 219, "protein_name": "Lipid transferase CIDEB", "gene_name": "CIDEB", "organism": "Bovine", "refseq_name": "lipid transferase CIDEB", "refseq_ac": "NP_001029739", "gene_names_uniprotkb": "CIDEB", "gene_names_refseq": "CIDEB", "protein_names_uniprotkb": "Lipid transferase CIDEB; Cell death-inducing DFFA-like effector B", "protein_names_refseq": "Cell death activator CIDE-B (Cell death-inducing DFFA-like effector B); lipid transferase CIDEB", "tax_id": 9913, "disease": "", "pathway": " (bta:528834)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Lipid transferase specifically expressed in hepatocytes, which promotes unilocular lipid droplet formation by mediating lipid droplet fusion. Lipid droplet fusion promotes their enlargement, restricting lipolysis and favoring lipid storage (By similarity). Localizes on the lipid droplet surface, at focal contact sites between lipid droplets, and mediates atypical lipid droplet fusion by promoting directional net neutral lipid transfer from the smaller to larger lipid droplets. The transfer direction may be driven by the internal pressure difference between the contacting lipid droplet pair (By similarity). Promotes lipid exchange and lipid droplet fusion in both small and large lipid droplet-containing hepatocytes. In addition to its role in lipid droplet fusion, also involved in cytoplasmic vesicle biogenesis and transport. Required for very-low-density lipoprotein (VLDL) lipidation and maturation. Probably involved in the biogenesis of VLDL transport vesicles by forming a COPII vesicle coat and facilitating the formation of endoplasmic reticulum-derived large vesicles. Also involved in sterol-regulated export of the SCAP-SREBP complex, composed of SCAP, SREBF1/SREBP1 and SREBF2/SREBP2, by promoting loading of SCAP-SREBP into COPII vesicles. May also activate apoptosis (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0060090 molecular adaptor activity;GO:0120013 lipid transfer activity;GO:0042802 identical protein binding;GO:0070300 phosphatidic acid binding", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0005811 lipid droplet;GO:0005789 endoplasmic reticulum membrane;GO:0030137 COPI-coated vesicle", "go_biological_process": "GO:0090110 COPII-coated vesicle cargo loading;GO:0006915 apoptotic process;GO:0034379 very-low-density lipoprotein particle assembly;GO:0019915 lipid storage;GO:0090207 regulation of triglyceride metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q3T191-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2YDI2-1", "uniprot_id": "ORC4_BOVIN", "mass": 50327.0, "length": 436, "protein_name": "Origin recognition complex subunit 4", "gene_name": "ORC4", "organism": "Bovine", "refseq_name": "origin recognition complex subunit 4", "refseq_ac": "NP_001039766", "gene_names_uniprotkb": "ORC4; ORC4L", "gene_names_refseq": "ORC4L; ORC4", "protein_names_uniprotkb": "Origin recognition complex subunit 4", "protein_names_refseq": "origin recognition complex subunit 4", "tax_id": 9913, "disease": "", "pathway": " (bta:529245); (R-BTA-176187); (R-BTA-68616); (R-BTA-68689); (R-BTA-68949); (R-BTA-68962)", "pathway_count": 6, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of the origin recognition complex (ORC) that binds origins of replication., [UniProtKB, UniProtKB]; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define origins of replication have not been identified yet. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. Binds histone H3 and H4 trimethylation marks H3K9me3, H3K27me3 and H4K20me3 (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003688 DNA replication origin binding;GO:0005524 ATP binding;GO:0000166 nucleotide binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005664 nuclear origin of replication recognition complex;GO:0005654 nucleoplasm;GO:0005730 nucleolus", "go_biological_process": "GO:0006270 DNA replication initiation;GO:0051258 protein polymerization;GO:0040038 polar body extrusion after meiotic divisions", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2YDI2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2YDD4-1", "uniprot_id": "S39AB_BOVIN", "mass": 35198.0, "length": 341, "protein_name": "Zinc transporter ZIP11", "gene_name": "SLC39A11", "organism": "Bovine", "refseq_name": "zinc transporter ZIP11", "refseq_ac": "NP_001069858", "gene_names_uniprotkb": "SLC39A11; ZIP11", "gene_names_refseq": "SLC39A11", "protein_names_uniprotkb": "Zinc transporter ZIP11; Solute carrier family 39 member 11; ZIP-11; Zrt- and Irt-like protein 11", "protein_names_refseq": "ZIP-11; solute carrier family 39 (metal ion transporter), member 11; zinc transporter ZIP11; zrt- and Irt-like protein 11", "tax_id": 9913, "disease": "", "pathway": " (bta:615681)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Zinc importer that regulates cytosolic zinc concentrations either via zinc influx from the extracellular compartment or efflux from intracellular organelles such as Golgi apparatus. May transport copper ions as well. The transport mechanism remains to be elucidated., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "2.7.11.1", "go_molecular_function": "GO:0005385 zinc ion transmembrane transporter activity;GO:0005375 copper ion transmembrane transporter activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005794 Golgi apparatus;GO:0005886 plasma membrane;GO:0016020 membrane", "go_biological_process": "GO:0071577 zinc ion transmembrane transport;GO:0071578 zinc ion import across plasma membrane", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2YDD4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3SYZ8-1", "uniprot_id": "PDLI3_BOVIN", "mass": 34353.0, "length": 316, "protein_name": "PDZ and LIM domain protein 3", "gene_name": "PDLIM3", "organism": "Bovine", "refseq_name": "PDZ and LIM domain protein 3", "refseq_ac": "NP_001029818", "gene_names_uniprotkb": "PDLIM3", "gene_names_refseq": "PDLIM3", "protein_names_uniprotkb": "PDZ and LIM domain protein 3", "protein_names_refseq": "PDZ and LIM domain protein 3", "tax_id": 9913, "disease": "", "pathway": " (bta:538516)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "May play a role in the organization of actin filament arrays within muscle cells., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0051371 muscle alpha-actinin binding;GO:0003779 actin binding;GO:0046872 metal ion binding;GO:0008092 cytoskeletal protein binding;GO:0008307 structural constituent of muscle", "go_cellular_component": "GO:0005912 adherens junction;GO:0001725 stress fiber;GO:0030018 Z disc;GO:0031941 filamentous actin;GO:0005737 cytoplasm", "go_biological_process": "GO:0007507 heart development;GO:0030036 actin cytoskeleton organization;GO:0061061 muscle structure development", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q3SYZ8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q32KL9-1", "uniprot_id": "BAP29_BOVIN", "mass": 28212.0, "length": 240, "protein_name": "B-cell receptor-associated protein 29", "gene_name": "BCAP29; DUS4L", "organism": "Bovine", "refseq_name": "B-cell receptor-associated protein 29", "refseq_ac": "NP_001033164", "gene_names_uniprotkb": "BCAP29; DUS4L", "gene_names_refseq": "BCAP29", "protein_names_uniprotkb": "B-cell receptor-associated protein 29; BCR-associated protein 29; Bap29", "protein_names_refseq": "B-cell receptor-associated protein 29; BCR-associated protein 29; bap29", "tax_id": 9913, "disease": "", "pathway": " (bta:511018)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs., [UniProtKB, UniProtKB, UniProtKB]; May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi. May be involved in CASP8-mediated apoptosis (By similarity)., [UniProtKB]; Plays a role in the export of secreted proteins in the ER., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "1.3.1.-", "go_molecular_function": "GO:0050660 flavin adenine dinucleotide binding;GO:0102266 tRNA-dihydrouridine20a synthase activity;GO:0102267 tRNA-dihydrouridine20b synthase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0006915 apoptotic process;GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0070973 protein localization to endoplasmic reticulum exit site", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q32KL9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q32LP7-1", "uniprot_id": "SKAP2_BOVIN", "mass": 40839.0, "length": 358, "protein_name": "Src kinase-associated phosphoprotein 2", "gene_name": "SKAP2", "organism": "Bovine", "refseq_name": "src kinase-associated phosphoprotein 2", "refseq_ac": "NP_001033303", "gene_names_uniprotkb": "SKAP2; SCAP2", "gene_names_refseq": "SCAP2; SKAP2", "protein_names_uniprotkb": "Src kinase-associated phosphoprotein 2; Src family-associated phosphoprotein 2", "protein_names_refseq": "src family associated phosphoprotein 2; src kinase-associated phosphoprotein 2", "tax_id": 9913, "disease": "", "pathway": " (bta:616545); (R-BTA-391160)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "May be involved in B-cell and macrophage adhesion processes. In B-cells, may act by coupling the B-cell receptor (BCR) to integrin activation. May play a role in src signaling pathway., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 11, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005886 plasma membrane", "go_biological_process": "GO:0042113 B cell activation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q32LP7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q32LE2-1", "uniprot_id": "GKAP1_BOVIN", "mass": 41881.0, "length": 363, "protein_name": "G kinase-anchoring protein 1", "gene_name": "GKAP1", "organism": "Bovine", "refseq_name": "G kinase-anchoring protein 1", "refseq_ac": "NP_001035663", "gene_names_uniprotkb": "GKAP1", "gene_names_refseq": "GKAP1", "protein_names_uniprotkb": "G kinase-anchoring protein 1", "protein_names_refseq": "G kinase-anchoring protein 1", "tax_id": 9913, "disease": "", "pathway": " (bta:613960)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Regulates insulin-dependent IRS1 tyrosine phosphorylation in adipocytes by modulating the availability of IRS1 to IR tyrosine kinase. Its association with IRS1 is required for insulin-induced translocation of SLC2A4 to the cell membrane. Involved in TNF-induced impairment of insulin-dependent IRS1 tyrosine phosphorylation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0042802 identical protein binding", "go_cellular_component": "GO:0005794 Golgi apparatus", "go_biological_process": "GO:0007165 signal transduction;GO:0007168 receptor guanylyl cyclase signaling pathway;GO:0046628 positive regulation of insulin receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q32LE2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3SZI1-1", "uniprot_id": "TINAG_BOVIN", "mass": 54235.0, "length": 476, "protein_name": "Tubulointerstitial nephritis antigen", "gene_name": "TINAG", "organism": "Bovine", "refseq_name": "tubulointerstitial nephritis antigen", "refseq_ac": "NP_001030279", "gene_names_uniprotkb": "TINAG", "gene_names_refseq": "TINAG", "protein_names_uniprotkb": "Tubulointerstitial nephritis antigen; TIN-Ag", "protein_names_refseq": "TIN-Ag; tubulointerstitial nephritis antigen", "tax_id": 9913, "disease": "", "pathway": " (bta:512517)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Mediates adhesion of proximal tubule epithelial cells via integrins alpha3-beta1 and alphaV-beta3. This is a non catalytic peptidase C1 family protein (By similarity)., [UniProtKB]", "predicted_glycosites": 5, "predicted_n_glycosites": 5, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008234 cysteine-type peptidase activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005764 lysosome;GO:0005604 basement membrane;GO:0005576 extracellular region", "go_biological_process": "GO:0006508 proteolysis;GO:0007155 cell adhesion", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q3SZI1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3SWY9-1", "uniprot_id": "RAB28_BOVIN", "mass": 24743.0, "length": 221, "protein_name": "Ras-related protein Rab-28", "gene_name": "RAB28", "organism": "Bovine", "refseq_name": "ras-related protein Rab-28", "refseq_ac": "NP_001029806", "gene_names_uniprotkb": "RAB28", "gene_names_refseq": "RAB28", "protein_names_uniprotkb": "Ras-related protein Rab-28; 3.6.5.2", "protein_names_refseq": "ras-related protein Rab-28", "tax_id": 9913, "disease": "", "pathway": " (bta:536021)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "30228185", "class_list": "", "function": "The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes (By similarity). Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion (By similarity). RAB28 is required for shedding and phagocytosis of cone cell outer segments (OS) discs in the retina (By similarity). Also participates in nuclear factor kappa-B p65/RELA nuclear transport in endothelial cells (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "3.6.5.2;3.6.5.5;3.6.5.-;3.6.5.3;2.7.11.1;3.6.1.5;3.6.1.15;3.6.5.4", "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0046872 metal ion binding;GO:0019003 GDP binding;GO:0003925 G protein activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0035253 ciliary rootlet;GO:0036064 ciliary basal body", "go_biological_process": "GO:0016192 vesicle-mediated transport;GO:0015031 protein transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q3SWY9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3SZ27-1", "uniprot_id": "MIC27_BOVIN", "mass": 29115.0, "length": 264, "protein_name": "MICOS complex subunit MIC27", "gene_name": "APOL; APOOL", "organism": "Bovine", "refseq_name": "MICOS complex subunit MIC27 precursor", "refseq_ac": "NP_001030203", "gene_names_uniprotkb": "APOL; APOOL; FAM121A; MIC27", "gene_names_refseq": "APOL; APOOL", "protein_names_uniprotkb": "MICOS complex subunit MIC27; Apolipoprotein O-like; Protein FAM121A", "protein_names_refseq": "MICOS complex subunit MIC27 precursor; MICOS complex subunit MIC27", "tax_id": 9913, "disease": "", "pathway": " (bta:506138); (R-BTA-114608)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0061617 MICOS complex", "go_biological_process": "GO:0042407 cristae formation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q3SZ27-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3T0L2-1", "uniprot_id": "ERP44_BOVIN", "mass": 46836.0, "length": 406, "protein_name": "Endoplasmic reticulum resident protein 44", "gene_name": "ERP44", "organism": "Bovine", "refseq_name": "endoplasmic reticulum resident protein 44 precursor", "refseq_ac": "NP_001030204", "gene_names_uniprotkb": "ERP44; TXNDC4", "gene_names_refseq": "ERP44; TXNDC4", "protein_names_uniprotkb": "Endoplasmic reticulum resident protein 44; ER protein 44; ERp44; Thioredoxin domain-containing protein 4", "protein_names_refseq": "ER protein 44; endoplasmic reticulum resident protein 44 precursor; endoplasmic reticulum resident protein 44; endoplasmic reticulum resident protein ERp44; thioredoxin domain containing 4 (endoplasmic reticulum); thioredoxin domain-containing protein 4", "tax_id": 9913, "disease": "", "pathway": " (bta:506157); (R-BTA-6798695)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Mediates thiol-dependent retention in the early secretory pathway, forming mixed disulfides with substrate proteins through its conserved CRFS motif. Inhibits the calcium channel activity of ITPR1. May have a role in the control of oxidative protein folding in the endoplasmic reticulum. Required to retain ERO1A and ERO1B in the endoplasmic reticulum., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003756 protein disulfide isomerase activity", "go_cellular_component": "GO:0005788 endoplasmic reticulum lumen;GO:0009986 cell surface;GO:0005789 endoplasmic reticulum membrane;GO:0005793 endoplasmic reticulum-Golgi intermediate compartment", "go_biological_process": "GO:0006457 protein folding;GO:0034976 response to endoplasmic reticulum stress;GO:0009100 glycoprotein metabolic process;GO:0006986 response to unfolded protein", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q3T0L2-1", "record_type": "protein" } ]