[ { "uniprot_canonical_ac": "A0A024BTL2-1", "uniprot_id": "A0A024BTL2_PIG", "mass": 44837.0, "length": 388, "protein_name": "phosphorylase kinase", "gene_name": "PHKG1", "organism": "Pig", "refseq_name": "phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform", "refseq_ac": "NP_001280073", "gene_names_uniprotkb": "PHKG1", "gene_names_refseq": "PHGK; PHKG1", "protein_names_uniprotkb": "phosphorylase kinase; 2.7.11.19", "protein_names_refseq": "phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform; phosphorylase kinase gamma 1; phosphorylase kinase gamma subunit", "tax_id": 9823, "disease": "", "pathway": " (ssc:397548)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "25340394;30300804;31443641;32543654", "class_list": "", "function": "Deep sequencing of PHKG1 revealed a point mutation (C>A) in a splice acceptor site of intron 9, resulting in a 32-bp deletion in the open reading frame and generating a premature stop codon. Publication Status: Online-Only, [RefSeq, PubMed]; Findings indicate that the genetic basis of muscle residual glycogen in swine can be mainly attributed to two major genes PRKAG3 and PHKG1 Publication Status: Online-Only, [RefSeq, PubMed]; The results suggest an effect of PHKG1 g.8283C>A SNP on meat water-holding cap and color in Italian heavy pigs., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A4X1SZ00;F1RIU5", "ec_number_list": "", "go_molecular_function": "GO:0004689 phosphorylase kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0005516 calmodulin binding;GO:0005524 ATP binding", "go_cellular_component": "GO:0005964 phosphorylase kinase complex;GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0044773 mitotic DNA damage checkpoint signaling;GO:0005980 glycogen catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A0A024BTL2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A286ZHZ3-1", "uniprot_id": "A0A286ZHZ3_PIG", "mass": 26169.0, "length": 228, "protein_name": "Translin", "gene_name": "TSN", "organism": "Pig", "refseq_name": "translin isoform X1", "refseq_ac": "XP_005671695", "gene_names_uniprotkb": "TSN", "gene_names_refseq": "TSN", "protein_names_uniprotkb": "Translin; Component 3 of promoter of RISC", "protein_names_refseq": "translin isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100519802); (R-SSC-426486)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "DNA-binding protein that specifically recognizes consensus sequences at the breakpoint junctions in chromosomal translocations, mostly involving immunoglobulin (Ig)/T-cell receptor gene segments. Seems to recognize single-stranded DNA ends generated by staggered breaks occurring at recombination hot spots., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Exhibits both single-stranded and double-stranded endoribonuclease activity. May act as an activator of RNA-induced silencing complex (RISC) by facilitating endonucleolytic cleavage of the siRNA passenger strand., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding;GO:0016787 hydrolase activity;GO:0042802 identical protein binding;GO:0046872 metal ion binding;GO:0004519 endonuclease activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm", "go_biological_process": "GO:0030422 siRNA processing;GO:0016070 RNA metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZHZ3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A286ZHZ6-1", "uniprot_id": "A0A286ZHZ6_PIG", "mass": 28620.0, "length": 256, "protein_name": "Proenkephalin-B", "gene_name": "PDYN", "organism": "Pig", "refseq_name": "proenkephalin-B isoform X1", "refseq_ac": "XP_020932975", "gene_names_uniprotkb": "PDYN", "gene_names_refseq": "PDYN", "protein_names_uniprotkb": "Proenkephalin-B; Beta-neoendorphin-dynorphin; Preprodynorphin", "protein_names_refseq": "proenkephalin-B isoform X1", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-111885); (R-SSC-202040); (R-SSC-375276); (R-SSC-418594)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Dynorphin peptides differentially regulate the kappa opioid receptor. Dynorphin A(1-13) has a typical opioid activity, it is 700 times more potent than Leu-enkephalin., [UniProtKB, UniProtKB]; Leu-enkephalins compete with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress., [UniProtKB, UniProtKB]; Leumorphin has a typical opioid activity and may have anti-apoptotic effect., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0031628 opioid receptor binding;GO:0001515 opioid peptide activity", "go_cellular_component": "GO:0098992 neuronal dense core vesicle;GO:0005576 extracellular region;GO:0005886 plasma membrane;GO:0030425 dendrite;GO:0043025 neuronal cell body", "go_biological_process": "GO:0007218 neuropeptide signaling pathway;GO:0007268 chemical synaptic transmission;GO:0007600 sensory perception", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZHZ6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A286ZI36-1", "uniprot_id": "A0A286ZI36_PIG", "mass": 71431.0, "length": 657, "protein_name": "Pyruvate kinase", "gene_name": "PKM", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "PKM", "gene_names_refseq": "", "protein_names_uniprotkb": "Pyruvate kinase; 2.7.1.40", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-6798695); (R-SSC-70171); (R-SSC-70268); (R-SSC-9861718)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Catalyzes the final rate-limiting step of glycolysis by mediating the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP. The ratio between the highly active tetrameric form and nearly inactive dimeric form determines whether glucose carbons are channeled to biosynthetic processes or used for glycolytic ATP production. The transition between the 2 forms contributes to the control of glycolysis and is important for tumor cell proliferation and survival., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0003729 mRNA binding;GO:0005524 ATP binding;GO:0016301 kinase activity;GO:0030955 potassium ion binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005791 rough endoplasmic reticulum;GO:0005829 cytosol;GO:0005929 cilium", "go_biological_process": "GO:2000767 positive regulation of cytoplasmic translation;GO:1903672 positive regulation of sprouting angiogenesis;GO:0032869 cellular response to insulin stimulus;GO:0006096 glycolytic process;GO:0061621 canonical glycolysis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZI36-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A286ZI70-1", "uniprot_id": "A0A286ZI70_PIG", "mass": 106952.0, "length": 939, "protein_name": "Protein O-mannosyl-transferase TMTC3", "gene_name": "TMTC3", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "TMTC3", "gene_names_refseq": "", "protein_names_uniprotkb": "Protein O-mannosyl-transferase TMTC3; 2.4.1.109; Transmembrane O-mannosyltransferase targeting cadherins 3; Transmembrane and tetratricopeptide repeat-containing 3", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Transfers mannosyl residues to the hydroxyl group of serine or threonine residues. The 4 members of the TMTC family are O-mannosyl-transferases dedicated primarily to the cadherin superfamily, each member seems to have a distinct role in decorating the cadherin domains with O-linked mannose glycans at specific regions. Also acts as O-mannosyl-transferase on other proteins such as PDIA3. Involved in the positive regulation of proteasomal protein degradation in the endoplasmic reticulum (ER), and the control of ER stress response., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A287A227", "ec_number_list": "", "go_molecular_function": "GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity;GO:0000030 mannosyltransferase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0016020 membrane", "go_biological_process": "GO:0034976 response to endoplasmic reticulum stress;GO:0035269 protein O-linked glycosylation via mannose;GO:1901800 positive regulation of proteasomal protein catabolic process;GO:0060255 regulation of macromolecule metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZI70-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A286ZI97-1", "uniprot_id": "A0A286ZI97_PIG", "mass": 24187.0, "length": 222, "protein_name": "Peptidoglycan-recognition protein", "gene_name": "PGLYRP1", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "PGLYRP1", "gene_names_refseq": "", "protein_names_uniprotkb": "Peptidoglycan-recognition protein", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-6798695); (R-SSC-6803157)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Innate immunity protein that plays several important functions in antimicrobial and antitumor defense systems., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0060090 molecular adaptor activity;GO:0042834 peptidoglycan binding;GO:0008745 N-acetylmuramoyl-L-alanine amidase activity;GO:0008270 zinc ion binding;GO:0048018 receptor ligand activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0006955 immune response;GO:0045087 innate immune response;GO:0050830 defense response to Gram-positive bacterium;GO:0061844 antimicrobial humoral immune response mediated by antimicrobial peptide;GO:0016045 detection of bacterium", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZI97-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A286ZIC0-1", "uniprot_id": "A0A286ZIC0_PIG", "mass": 61705.0, "length": 565, "protein_name": "Reticulophagy regulator 1", "gene_name": "RETREG1", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "RETREG1", "gene_names_refseq": "", "protein_names_uniprotkb": "Reticulophagy regulator 1", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (ssc:100625174)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0140506 endoplasmic reticulum-autophagosome adaptor activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane;GO:0005801 cis-Golgi network", "go_biological_process": "GO:0019233 sensory perception of pain;GO:0043524 negative regulation of neuron apoptotic process;GO:0061709 reticulophagy", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZIC0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A286ZID7-1", "uniprot_id": "A0A286ZID7_PIG", "mass": 32213.0, "length": 291, "protein_name": "Transmembrane protein 41B", "gene_name": "TMEM41B", "organism": "Pig", "refseq_name": "transmembrane protein 41B isoform X1", "refseq_ac": "XP_003129438", "gene_names_uniprotkb": "TMEM41B", "gene_names_refseq": "TMEM41B", "protein_names_uniprotkb": "Transmembrane protein 41B", "protein_names_refseq": "transmembrane protein 41B isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100519436)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Phospholipid scramblase involved in lipid homeostasis and membrane dynamics processes. Has phospholipid scramblase activity toward cholesterol and phosphatidylserine, as well as phosphatidylethanolamine and phosphatidylcholine. Required for autophagosome formation: participates in early stages of autophagosome biogenesis at the endoplasmic reticulum (ER) membrane by reequilibrating the leaflets of the ER as lipids are extracted by ATG2 (ATG2A or ATG2B) to mediate autophagosome assembly. In addition to autophagy, involved in other processes in which phospholipid scramblase activity is required. Required for normal motor neuron development., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0017128 phospholipid scramblase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane;GO:0044233 mitochondria-associated endoplasmic reticulum membrane contact site;GO:0016020 membrane", "go_biological_process": "GO:0000045 autophagosome assembly;GO:0044830 host-mediated perturbation of viral RNA genome replication;GO:0032365 intracellular lipid transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZID7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A286ZIJ7-1", "uniprot_id": "A0A286ZIJ7_PIG", "mass": 7374.0, "length": 66, "protein_name": "Stress-associated endoplasmic reticulum protein", "gene_name": "SERP1", "organism": "Pig", "refseq_name": "stress-associated endoplasmic reticulum protein 1", "refseq_ac": "NP_001230189", "gene_names_uniprotkb": "SERP1", "gene_names_refseq": "SERP1", "protein_names_uniprotkb": "Stress-associated endoplasmic reticulum protein", "protein_names_refseq": "stress-associated endoplasmic reticulum protein 1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100156392); (R-SSC-9609523)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Interacts with target proteins during their translocation into the lumen of the endoplasmic reticulum. Protects unfolded target proteins against degradation during ER stress. May facilitate glycosylation of target proteins after termination of ER stress. May modulate the use of N-glycosylation sites on target proteins., [UniProtKB, UniProtKB]; Interacts with target proteins during translocation into the lumen of the endoplasmic reticulum. Protects unfolded target proteins against degradation and facilitate correct glycosylation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane;GO:0005881 cytoplasmic microtubule", "go_biological_process": "GO:0030968 endoplasmic reticulum unfolded protein response", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZIJ7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A286ZIS3-1", "uniprot_id": "A0A286ZIS3_PIG", "mass": 29315.0, "length": 262, "protein_name": "Dual specificity phosphatase 29", "gene_name": "DUSP29", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "DUSP29", "gene_names_refseq": "", "protein_names_uniprotkb": "Dual specificity phosphatase 29; 3.1.3.16; 3.1.3.48; Dual specificity phosphatase DUPD1", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (ssc:100155430)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0042803 protein homodimerization activity;GO:0004722 protein serine/threonine phosphatase activity;GO:0008138 protein tyrosine/serine/threonine phosphatase activity;GO:0033549 MAP kinase phosphatase activity;GO:0004725 protein tyrosine phosphatase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0032991 protein-containing complex", "go_biological_process": "GO:0042593 glucose homeostasis;GO:0070373 negative regulation of ERK1 and ERK2 cascade;GO:0042692 muscle cell differentiation;GO:0043409 negative regulation of MAPK cascade", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZIS3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A8W4F8R6-1", "uniprot_id": "A0A8W4F8R6_PIG", "mass": 64217.0, "length": 587, "protein_name": "Amino acid transporter", "gene_name": "SLC1A3", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "SLC1A3", "gene_names_refseq": "", "protein_names_uniprotkb": "Amino acid transporter", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-210455); (R-SSC-210500); (R-SSC-9958863)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0046872 metal ion binding;GO:0015293 symporter activity;GO:0015175 neutral L-amino acid transmembrane transporter activity;GO:0005314 high-affinity L-glutamate transmembrane transporter activity;GO:0015501 glutamate:sodium symporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0009986 cell surface;GO:0043025 neuronal cell body;GO:0045202 synapse;GO:0043005 neuron projection", "go_biological_process": "GO:0070633 transepithelial transport;GO:0015813 L-glutamate transmembrane transport;GO:0150104 transport across blood-brain barrier;GO:0070778 L-aspartate transmembrane transport;GO:1902475 L-alpha-amino acid transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A8W4F8R6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A5G2QNH5-1", "uniprot_id": "A0A5G2QNH5_PIG", "mass": 81891.0, "length": 717, "protein_name": "G protein-coupled receptor kinase", "gene_name": "GRK2", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "GRK2", "gene_names_refseq": "", "protein_names_uniprotkb": "G protein-coupled receptor kinase; 2.7.11.-", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-111933); (R-SSC-416476); (R-SSC-418555); (R-SSC-5635838); (R-SSC-8856825)", "pathway_count": 5, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them. Phosphorylates catecholamine-activated ADRB2 to regulate physiological cardiomyocyte contraction rate responses. Also phosphorylates ligand-bound C3a and C5a anaphylatoxin receptors (C3AR1 and C5AR1, respectively), leading to receptor desensitization. Key regulator of LPAR1 signaling. Competes with RALA for binding to LPAR1 thus affecting the signaling properties of the receptor. Desensitizes LPAR1 and LPAR2 in a phosphorylation-independent manner. Positively regulates ciliary smoothened (SMO)-dependent Hedgehog (Hh) signaling pathway by facilitating the trafficking of SMO into the cilium and the stimulation of SMO activity. Inhibits relaxation of airway smooth muscle in response to blue light., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0004703 G protein-coupled receptor kinase activity;GO:0047696 beta-adrenergic receptor kinase activity;GO:0001664 G protein-coupled receptor binding;GO:0031755 Edg-2 lysophosphatidic acid receptor binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0098794 postsynapse;GO:0098793 presynapse;GO:0005829 cytosol", "go_biological_process": "GO:0007165 signal transduction;GO:0007186 G protein-coupled receptor signaling pathway;GO:0031623 receptor internalization;GO:0060048 cardiac muscle contraction;GO:0046718 symbiont entry into host cell", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A5G2QNH5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A286ZJB7-1", "uniprot_id": "A0A286ZJB7_PIG", "mass": 36405.0, "length": 326, "protein_name": "Voltage-dependent calcium channel gamma-4 subunit", "gene_name": "CACNG4", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "CACNG4", "gene_names_refseq": "", "protein_names_uniprotkb": "Voltage-dependent calcium channel gamma-4 subunit", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-112308); (R-SSC-399719); (R-SSC-5576892); (R-SSC-5576893); (R-SSC-5682910)", "pathway_count": 5, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005246 calcium channel regulator activity;GO:0005245 voltage-gated calcium channel activity;GO:0016247 channel regulator activity", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0032281 AMPA glutamate receptor complex;GO:1990454 L-type voltage-gated calcium channel complex;GO:0036477 somatodendritic compartment;GO:0098839 postsynaptic density membrane", "go_biological_process": "GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0051968 positive regulation of synaptic transmission, glutamatergic;GO:0019226 transmission of nerve impulse;GO:0098970 postsynaptic neurotransmitter receptor diffusion trapping", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZJB7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A286ZJG2-1", "uniprot_id": "A0A286ZJG2_PIG", "mass": 89828.0, "length": 803, "protein_name": "E3 ubiquitin-protein ligase UHRF", "gene_name": "UHRF2", "organism": "Pig", "refseq_name": "E3 ubiquitin-protein ligase UHRF2 isoform X1", "refseq_ac": "XP_020919597", "gene_names_uniprotkb": "UHRF2", "gene_names_refseq": "UHRF2", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase UHRF; 2.3.2.27; RING-type E3 ubiquitin transferase UHRF; Ubiquitin-like PHD and RING finger domain-containing protein; Ubiquitin-like-containing PHD and RING finger domains protein", "protein_names_refseq": "E3 ubiquitin-protein ligase UHRF2 isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:102168004)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Multi domain E3 ubiquitin ligase that also plays a role in DNA methylation and histone modifications., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity;GO:0042393 histone binding;GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005721 pericentric heterochromatin", "go_biological_process": "GO:0030154 cell differentiation;GO:0016567 protein ubiquitination;GO:0051865 protein autoubiquitination;GO:0051726 regulation of cell cycle;GO:0044027 negative regulation of gene expression via chromosomal CpG island methylation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZJG2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A286ZJI9-1", "uniprot_id": "A0A286ZJI9_PIG", "mass": 45764.0, "length": 429, "protein_name": "PBX homeobox 2", "gene_name": "PBX2", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "PBX2", "gene_names_refseq": "", "protein_names_uniprotkb": "PBX homeobox 2", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003682 chromatin binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0140297 DNA-binding transcription factor binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005667 transcription regulator complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0007420 brain development;GO:0009887 animal organ morphogenesis;GO:0048666 neuron development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZJI9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A286ZJM4-1", "uniprot_id": "A0A286ZJM4_PIG", "mass": 81326.0, "length": 719, "protein_name": "DNA replication licensing factor MCM7", "gene_name": "MCM7", "organism": "Pig", "refseq_name": "DNA replication licensing factor MCM7 isoform X1", "refseq_ac": "XP_020941852", "gene_names_uniprotkb": "MCM7", "gene_names_refseq": "MCM7", "protein_names_uniprotkb": "DNA replication licensing factor MCM7; 3.6.4.12", "protein_names_refseq": "DNA replication licensing factor MCM7 isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:110259871); (R-SSC-176187); (R-SSC-68867); (R-SSC-68949); (R-SSC-68962); (R-SSC-69052)", "pathway_count": 6, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0003697 single-stranded DNA binding;GO:0003678 DNA helicase activity;GO:0003677 DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005694 chromosome;GO:0042555 MCM complex", "go_biological_process": "GO:0006271 DNA strand elongation involved in DNA replication;GO:0006270 DNA replication initiation;GO:0000727 double-strand break repair via break-induced replication", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZJM4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A286ZJN6-1", "uniprot_id": "A0A286ZJN6_PIG", "mass": 70908.0, "length": 651, "protein_name": "Dual specificity phosphatase 16", "gene_name": "DUSP16", "organism": "Pig", "refseq_name": "dual specificity protein phosphatase 16", "refseq_ac": "XP_020947997", "gene_names_uniprotkb": "DUSP16", "gene_names_refseq": "DUSP16", "protein_names_uniprotkb": "Dual specificity phosphatase 16", "protein_names_refseq": "dual specificity protein phosphatase 16", "tax_id": 9823, "disease": "", "pathway": " (ssc:100620494); (R-SSC-112409); (R-SSC-5675221)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0048273 mitogen-activated protein kinase p38 binding;GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity;GO:0008330 protein tyrosine/threonine phosphatase activity;GO:0008432 JUN kinase binding;GO:0140597 protein carrier chaperone", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZJN6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A5K1TV69-1", "uniprot_id": "A0A5K1TV69_PIG", "mass": 96065.0, "length": 865, "protein_name": "Semaphorin-4D", "gene_name": "SEMA4D", "organism": "Pig", "refseq_name": "semaphorin-4D isoform X1", "refseq_ac": "XP_005670454", "gene_names_uniprotkb": "SEMA4D", "gene_names_refseq": "SEMA4D", "protein_names_uniprotkb": "Semaphorin-4D", "protein_names_refseq": "semaphorin-4D isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100152598); (R-SSC-416550); (R-SSC-416572); (R-SSC-416700)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Cell surface receptor for PLXNB1 and PLXNB2 that plays an important role in cell-cell signaling. Regulates GABAergic synapse development. Promotes the development of inhibitory synapses in a PLXNB1-dependent manner. Modulates the complexity and arborization of developing neurites in hippocampal neurons by activating PLXNB1 and interaction with PLXNB1 mediates activation of RHOA. Promotes the migration of cerebellar granule cells. Plays a role in the immune system; induces B-cells to aggregate and improves their viability (in vitro). Induces endothelial cell migration through the activation of PTK2B/PYK2, SRC, and the phosphatidylinositol 3-kinase-AKT pathway., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0030215 semaphorin receptor binding;GO:0004888 transmembrane signaling receptor activity;GO:0038191 neuropilin binding;GO:0045499 chemorepellent activity", "go_cellular_component": "GO:0016020 membrane;GO:0098982 GABA-ergic synapse;GO:0002116 semaphorin receptor complex;GO:0005615 extracellular space;GO:0005886 plasma membrane", "go_biological_process": "GO:0007399 nervous system development;GO:0030154 cell differentiation;GO:0043931 ossification involved in bone maturation;GO:0061430 bone trabecula morphogenesis;GO:0070486 leukocyte aggregation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A5K1TV69-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A286ZJW9-1", "uniprot_id": "A0A286ZJW9_PIG", "mass": 27567.0, "length": 239, "protein_name": "Derlin", "gene_name": "DERL2", "organism": "Pig", "refseq_name": "derlin-2", "refseq_ac": "XP_020923382", "gene_names_uniprotkb": "DERL2", "gene_names_refseq": "DERL2", "protein_names_uniprotkb": "Derlin", "protein_names_refseq": "derlin-2", "tax_id": 9823, "disease": "", "pathway": " (ssc:110256099); (R-SSC-382556); (R-SSC-5358346); (R-SSC-9931269)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A4X1UKD4", "ec_number_list": "", "go_molecular_function": "GO:0005047 signal recognition particle binding", "go_cellular_component": "GO:0005769 early endosome;GO:0005789 endoplasmic reticulum membrane;GO:0005770 late endosome", "go_biological_process": "GO:0008284 positive regulation of cell population proliferation;GO:0030307 positive regulation of cell growth;GO:0030968 endoplasmic reticulum unfolded protein response;GO:0036503 ERAD pathway;GO:0030970 retrograde protein transport, ER to cytosol", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZJW9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A286ZJX5-1", "uniprot_id": "A0A286ZJX5_PIG", "mass": 141296.0, "length": 1231, "protein_name": "Cohesin subunit SA", "gene_name": "STAG2", "organism": "Pig", "refseq_name": "cohesin subunit SA-2 isoform X2", "refseq_ac": "XP_013841858", "gene_names_uniprotkb": "STAG2", "gene_names_refseq": "STAG2", "protein_names_uniprotkb": "Cohesin subunit SA; SCC3 homolog; Stromal antigen", "protein_names_refseq": "cohesin subunit SA-2 isoform X2", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-2467813); (R-SSC-2468052); (R-SSC-2470946); (R-SSC-2500257); (R-SSC-3108214)", "pathway_count": 5, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A4X1W7Y7", "ec_number_list": "", "go_molecular_function": "GO:0003682 chromatin binding", "go_cellular_component": "GO:0005634 nucleus;GO:0000775 chromosome, centromeric region;GO:0000785 chromatin;GO:0008278 cohesin complex;GO:0005654 nucleoplasm", "go_biological_process": "GO:0007059 chromosome segregation;GO:0051301 cell division;GO:0007062 sister chromatid cohesion;GO:0090307 mitotic spindle assembly", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZJX5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A286ZK24-1", "uniprot_id": "A0A286ZK24_PIG", "mass": 44990.0, "length": 393, "protein_name": "4-hydroxyphenylpyruvate dioxygenase", "gene_name": "HPD", "organism": "Pig", "refseq_name": "4-hydroxyphenylpyruvate dioxygenase", "refseq_ac": "NP_001335893", "gene_names_uniprotkb": "HPD", "gene_names_refseq": "HPD", "protein_names_uniprotkb": "4-hydroxyphenylpyruvate dioxygenase", "protein_names_refseq": "4-hydroxyphenylpyruvate dioxygenase; 4-hydroxyphenylpyruvic acid dioxygenase; 4-hydroxyphenylpyruvic acid oxidase; 4HPPD; HPPDase", "tax_id": 9823, "disease": "", "pathway": " (ssc:397443); (R-SSC-8963684)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Catalyzes the conversion of 4-hydroxyphenylpyruvic acid to homogentisic acid, one of the steps in tyrosine catabolism., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A4X1U570", "ec_number_list": "", "go_molecular_function": "GO:0003868 4-hydroxyphenylpyruvate dioxygenase activity;GO:0042803 protein homodimerization activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006559 L-phenylalanine catabolic process;GO:0006572 L-tyrosine catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZK24-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A286ZK36-1", "uniprot_id": "A0A286ZK36_PIG", "mass": 54572.0, "length": 479, "protein_name": "Ubiquitin carboxyl-terminal hydrolase", "gene_name": "USP22", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "USP22", "gene_names_refseq": "", "protein_names_uniprotkb": "Ubiquitin carboxyl-terminal hydrolase; 3.4.19.12", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003713 transcription coactivator activity;GO:0008270 zinc ion binding;GO:0019899 enzyme binding;GO:0004843 cysteine-type deubiquitinase activity;GO:0010485 histone H4 acetyltransferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0000124 SAGA complex", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0006508 proteolysis;GO:0016579 protein deubiquitination;GO:0045931 positive regulation of mitotic cell cycle;GO:0000086 G2/M transition of mitotic cell cycle", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZK36-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A286ZK88-1", "uniprot_id": "DCTN5_PIG", "mass": 20127.0, "length": 182, "protein_name": "Dynactin subunit 5", "gene_name": "DCTN5", "organism": "Pig", "refseq_name": "dynactin subunit 5", "refseq_ac": "XP_020942125", "gene_names_uniprotkb": "DCTN5", "gene_names_refseq": "DCTN5", "protein_names_uniprotkb": "Dynactin subunit 5", "protein_names_refseq": "dynactin subunit 5", "tax_id": 9823, "disease": "", "pathway": " (ssc:100524641); (R-SSC-2132295); (R-SSC-3371497); (R-SSC-6807878)", "pathway_count": 4, "publication_count": 6, "publication_id_list": "25814576;29420470;30723633;32543654;33734450;36071160", "class_list": "", "function": "Part of the dynactin complex that activates the molecular motor dynein for ultra-processive transport along microtubules., [UniProtKB, PubMed, PubMed, PubMed, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A0J9X291", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005813 centrosome;GO:0005869 dynactin complex;GO:0000776 kinetochore;GO:0005856 cytoskeleton", "go_biological_process": "GO:0007017 microtubule-based process", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "A0A286ZK88-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A286ZKA4-1", "uniprot_id": "A0A286ZKA4_PIG", "mass": 49946.0, "length": 446, "protein_name": "D-ribitol-5-phosphate cytidylyltransferase", "gene_name": "CRPPA", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "CRPPA", "gene_names_refseq": "", "protein_names_uniprotkb": "D-ribitol-5-phosphate cytidylyltransferase; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase-like protein; 2.7.7.40; Isoprenoid synthase domain-containing protein", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-9939291)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Cytidylyltransferase required for protein O-linked mannosylation. Catalyzes the formation of CDP-ribitol nucleotide sugar from D-ribitol 5-phosphate. CDP-ribitol is a substrate of FKTN during the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity. Shows activity toward other pentose phosphate sugars and mediates formation of CDP-ribulose or CDP-ribose using CTP and ribulose-5-phosphate or ribose-5-phosphate, respectively. Not involved in dolichol production., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0042803 protein homodimerization activity;GO:0047349 D-ribitol-5-phosphate cytidylyltransferase activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0035269 protein O-linked glycosylation via mannose;GO:0008299 isoprenoid biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZKA4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A286ZKD4-1", "uniprot_id": "A0A286ZKD4_PIG", "mass": 75519.0, "length": 684, "protein_name": "Electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial", "gene_name": "SLC25A13", "organism": "Pig", "refseq_name": "calcium-binding mitochondrial carrier protein Aralar2 isoform X4", "refseq_ac": "XP_003130208", "gene_names_uniprotkb": "SLC25A13", "gene_names_refseq": "SLC25A13", "protein_names_uniprotkb": "Electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial; Solute carrier family 25 member 13", "protein_names_refseq": "calcium-binding mitochondrial carrier protein Aralar2 isoform X4", "tax_id": 9823, "disease": "", "pathway": " (ssc:100524162); (R-SSC-8963693); (R-SSC-9856872)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Mitochondrial electrogenic aspartate/glutamate antiporter that favors efflux of aspartate and entry of glutamate and proton within the mitochondria as part of the malate-aspartate shuttle. Substrate exchange across the membrane occurs consecutively with one substrate being transported first, then dissociating from the substrate binding site before the second substrate binds for transport in the opposite direction. Also mediates the uptake of L-cysteinesulfinate (3-sulfino-L-alanine) by mitochondria in exchange for L-glutamate and proton. Can also exchange L-cysteinesulfinate with aspartate in their anionic form without any proton translocation. Lacks transport activity towards gamma-aminobutyric acid (GABA)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A287ALB9", "ec_number_list": "", "go_molecular_function": "GO:0042802 identical protein binding;GO:0005509 calcium ion binding;GO:0005313 L-glutamate transmembrane transporter activity;GO:0015183 L-aspartate transmembrane transporter activity;GO:0000514 3-sulfino-L-alanine: proton, glutamate antiporter activity", "go_cellular_component": "GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0051592 response to calcium ion;GO:0006754 ATP biosynthetic process;GO:0006094 gluconeogenesis;GO:0045333 cellular respiration;GO:0015810 aspartate transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZKD4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A286ZKD7-1", "uniprot_id": "A0A286ZKD7_PIG", "mass": 45088.0, "length": 396, "protein_name": "Ras-related GTP-binding protein", "gene_name": "RRAGD", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "RRAGD", "gene_names_refseq": "", "protein_names_uniprotkb": "Ras-related GTP-binding protein", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-1632852); (R-SSC-165159); (R-SSC-166208); (R-SSC-380972); (R-SSC-5628897); (R-SSC-8943724); (R-SSC-9639288)", "pathway_count": 7, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0060090 molecular adaptor activity;GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0046982 protein heterodimerization activity;GO:0051020 GTPase binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0005764 lysosome;GO:0005765 lysosomal membrane", "go_biological_process": "GO:1904263 positive regulation of TORC1 signaling;GO:0010507 negative regulation of autophagy;GO:0009267 cellular response to starvation;GO:1990253 cellular response to leucine starvation;GO:0071233 cellular response to L-leucine", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZKD7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A286ZKF4-1", "uniprot_id": "A0A286ZKF4_PIG", "mass": 65568.0, "length": 595, "protein_name": "Cholinergic receptor nicotinic alpha 4 subunit", "gene_name": "CHRNA4", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "CHRNA4", "gene_names_refseq": "", "protein_names_uniprotkb": "Cholinergic receptor nicotinic alpha 4 subunit", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-629594); (R-SSC-629597)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0015464 acetylcholine receptor activity;GO:0022848 acetylcholine-gated monoatomic cation-selective channel activity;GO:0140658 ATP-dependent chromatin remodeler activity;GO:0004888 transmembrane signaling receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005892 acetylcholine-gated channel complex;GO:0045202 synapse;GO:0045211 postsynaptic membrane;GO:0043005 neuron projection", "go_biological_process": "GO:0006281 DNA repair;GO:0006979 response to oxidative stress;GO:0007271 synaptic transmission, cholinergic;GO:0007274 neuromuscular synaptic transmission;GO:0035094 response to nicotine", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZKF4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A286ZKN9-1", "uniprot_id": "A0A286ZKN9_PIG", "mass": 57508.0, "length": 508, "protein_name": "Diacylglycerol kinase", "gene_name": "DGKE", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "DGKE", "gene_names_refseq": "", "protein_names_uniprotkb": "Diacylglycerol kinase; 2.7.1.107; DAG kinase", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-114508)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Membrane-bound diacylglycerol kinase that converts diacylglycerol/DAG into phosphatidic acid/phosphatidate/PA and regulates the respective levels of these two bioactive lipids. Thereby, acts as a central switch between the signaling pathways activated by these second messengers with different cellular targets and opposite effects in numerous biological processes. Also plays an important role in the biosynthesis of complex lipids. Displays specificity for diacylglycerol substrates with an arachidonoyl acyl chain at the sn-2 position, with the highest activity toward 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol the main diacylglycerol intermediate within the phosphatidylinositol turnover cycle. Can also phosphorylate diacylglycerol substrates with a linoleoyl acyl chain at the sn-2 position but much less efficiently., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004143 ATP-dependent diacylglycerol kinase activity;GO:0005524 ATP binding;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0016020 membrane;GO:0098978 glutamatergic synapse;GO:0005829 cytosol", "go_biological_process": "GO:0046474 glycerophospholipid biosynthetic process;GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway;GO:0046486 glycerolipid metabolic process;GO:0007165 signal transduction;GO:0046339 diacylglycerol metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZKN9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A286ZKS9-1", "uniprot_id": "A0A286ZKS9_PIG", "mass": 117560.0, "length": 1029, "protein_name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1", "gene_name": "SMARCAD1", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "SMARCAD1", "gene_names_refseq": "", "protein_names_uniprotkb": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Protein that possesses intrinsic ATP-dependent nucleosome-remodeling activity and is both required for DNA repair and heterochromatin organization. Combines the ATP-dependent ability to exchange histones, with the chaperone-like ATP-independent activity to deposit histones and assemble nucleosomes. Promotes DNA end resection of double-strand breaks (DSBs) following DNA damage: probably acts by weakening histone DNA interactions in nucleosomes flanking DSBs. Required for the restoration of heterochromatin organization after replication. Acts at replication sites to facilitate the maintenance of heterochromatin by directing H3 and H4 histones deacetylation, H3 'Lys-9' trimethylation (H3K9me3) and restoration of silencing., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0003682 chromatin binding;GO:0005524 ATP binding;GO:0016787 hydrolase activity;GO:0043130 ubiquitin binding", "go_cellular_component": "GO:0043596 nuclear replication fork;GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0000785 chromatin;GO:0035861 site of double-strand break", "go_biological_process": "GO:0000018 regulation of DNA recombination;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0051304 chromosome separation;GO:0000729 DNA double-strand break processing;GO:0031507 heterochromatin formation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZKS9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A286ZKU4-1", "uniprot_id": "A0A286ZKU4_PIG", "mass": 23507.0, "length": 209, "protein_name": "Multicilin", "gene_name": "GMNN", "organism": "Pig", "refseq_name": "geminin isoform X3", "refseq_ac": "XP_003128251", "gene_names_uniprotkb": "GMNN", "gene_names_refseq": "GMNN", "protein_names_uniprotkb": "Multicilin; Multiciliate differentiation and DNA synthesis-associated cell cycle protein; Protein Idas", "protein_names_refseq": "geminin isoform X3", "tax_id": 9823, "disease": "", "pathway": " (ssc:100515035); (R-SSC-68867); (R-SSC-68962); (R-SSC-69052)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Transcription regulator specifically required for multiciliate cell differentiation. Acts in a multiprotein complex containing E2F4 and E2F5 that binds and activates genes required for centriole biogenesis. Required for the deuterosome-mediated acentriolar pathway. Plays a role in mitotic cell cycle progression by promoting cell cycle exit. Modulates GMNN activity by reducing its affinity for CDT1., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A481D4V5", "ec_number_list": "", "go_molecular_function": "GO:0003682 chromatin binding;GO:0003714 transcription corepressor activity;GO:0042826 histone deacetylase binding;GO:0003712 transcription coregulator activity;GO:0140297 DNA-binding transcription factor binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0017053 transcription repressor complex", "go_biological_process": "GO:0030174 regulation of DNA-templated DNA replication initiation;GO:0045892 negative regulation of DNA-templated transcription;GO:0030030 cell projection organization;GO:0045786 negative regulation of cell cycle;GO:0065003 protein-containing complex assembly", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZKU4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A286ZKW2-1", "uniprot_id": "A0A286ZKW2_PIG", "mass": 58389.0, "length": 521, "protein_name": "Paraspeckle component 1", "gene_name": "PSPC1", "organism": "Pig", "refseq_name": "paraspeckle component 1 isoform X1", "refseq_ac": "XP_020921077", "gene_names_uniprotkb": "PSPC1", "gene_names_refseq": "PSPC1", "protein_names_uniprotkb": "Paraspeckle component 1", "protein_names_refseq": "paraspeckle component 1 isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100520511)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0016607 nuclear speck;GO:0001650 fibrillar center;GO:0016363 nuclear matrix;GO:0042382 paraspeckles", "go_biological_process": "GO:0006355 regulation of DNA-templated transcription;GO:0045892 negative regulation of DNA-templated transcription;GO:0042752 regulation of circadian rhythm;GO:0002218 activation of innate immune response;GO:0140694 membraneless organelle assembly", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A286ZKW2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A5G2R0L1-1", "uniprot_id": "A0A5G2R0L1_PIG", "mass": 141916.0, "length": 1265, "protein_name": "HECT-type E3 ubiquitin transferase", "gene_name": "NEDD4L", "organism": "Pig", "refseq_name": "E3 ubiquitin-protein ligase NEDD4-like isoform X1", "refseq_ac": "XP_020929502", "gene_names_uniprotkb": "NEDD4L", "gene_names_refseq": "NEDD4L", "protein_names_uniprotkb": "HECT-type E3 ubiquitin transferase; 2.3.2.26", "protein_names_refseq": "E3 ubiquitin-protein ligase NEDD4-like isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100512083)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0061630 ubiquitin protein ligase activity;GO:0019870 potassium channel inhibitor activity;GO:0019871 sodium channel inhibitor activity;GO:0044325 transmembrane transporter binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0016324 apical plasma membrane;GO:0005794 Golgi apparatus;GO:0005771 multivesicular body", "go_biological_process": "GO:0016567 protein ubiquitination;GO:0051049 regulation of transport;GO:0051603 proteolysis involved in protein catabolic process;GO:1903861 positive regulation of dendrite extension;GO:1903765 negative regulation of potassium ion export across plasma membrane", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A5G2R0L1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D2WKD8-1", "uniprot_id": "AT1A2_PIG", "mass": 112208.0, "length": 1020, "protein_name": "Sodium/potassium-transporting ATPase subunit alpha-2", "gene_name": "ATP1A1; 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It undergoes ATP-driven conformational changes that allow alternating binding and release of Na(+) and K(+) ions across the membrane (By similarity). This process maintains essential Na(+) and K(+) gradients for membrane potential and cellular function (By similarity)., [UniProtKB, UniProtKB, UniProtKB]; The ATP1A2 genotype is highly associated with muscle electric conductivity in Duroc pigs, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, 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communication;GO:0071383 cellular response to steroid hormone stimulus", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "D2WKD8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A5G2R4Q7-1", "uniprot_id": "A0A5G2R4Q7_PIG", "mass": 90458.0, "length": 786, "protein_name": "Vacuolar protein sorting-associated protein 35", "gene_name": "VPS35", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "VPS35", "gene_names_refseq": "", "protein_names_uniprotkb": "Vacuolar protein sorting-associated protein 35", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-3238698)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Plays a role in vesicular protein sorting., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, 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"ec_number_list": "", "go_molecular_function": "GO:0031748 D1 dopamine receptor binding", "go_cellular_component": "GO:0030906 retromer, cargo-selective complex;GO:0005829 cytosol;GO:0005769 early endosome;GO:0005770 late endosome;GO:0099073 mitochondrion-derived vesicle", "go_biological_process": "GO:0015031 protein transport;GO:0042147 retrograde transport, endosome to Golgi;GO:0050793 regulation of developmental process;GO:0099639 neurotransmitter receptor transport, endosome to plasma membrane;GO:0010628 positive regulation of gene expression", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A5G2R4Q7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A5G2R128-1", "uniprot_id": "A0A5G2R128_PIG", "mass": 216410.0, "length": 1928, "protein_name": "Receptor-type tyrosine-protein phosphatase delta", "gene_name": "PTPRD", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "PTPRD", "gene_names_refseq": "", "protein_names_uniprotkb": "Receptor-type tyrosine-protein phosphatase delta; 3.1.3.48", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Can bidirectionally induce pre- and post-synaptic differentiation of neurons by mediating interaction with IL1RAP and IL1RAPL1 trans-synaptically. Involved in pre-synaptic differentiation through interaction with SLITRK2., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004725 protein tyrosine phosphatase activity;GO:0005102 signaling receptor binding;GO:0050839 cell adhesion molecule binding", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0005886 plasma membrane;GO:0042734 presynaptic membrane;GO:0098686 hippocampal mossy fiber to CA3 synapse;GO:0098685 Schaffer collateral - CA1 synapse", "go_biological_process": "GO:0099054 presynapse assembly;GO:0099560 synaptic membrane adhesion;GO:0099537 trans-synaptic signaling;GO:0098609 cell-cell adhesion;GO:0030182 neuron differentiation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A5G2R128-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1RLV4-1", "uniprot_id": "F1RLV4_PIG", "mass": 42916.0, "length": 375, "protein_name": "Phosphatidylserine decarboxylase proenzyme, mitochondrial", "gene_name": "PISD", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "PISD", "gene_names_refseq": "", "protein_names_uniprotkb": "Phosphatidylserine decarboxylase proenzyme, mitochondrial; 4.1.1.65", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine. May be involved in lipid droplet biogenesis at the endoplasmic reticulum membrane., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, 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promoter-specific chromatin binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005730 nucleolus;GO:0016604 nuclear body;GO:0035098 ESC/E(Z) complex;GO:0032993 protein-DNA complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006325 chromatin organization;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0045596 negative regulation of cell differentiation;GO:0140718 facultative heterochromatin formation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1RKV6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1RR02-1", "uniprot_id": "F1RR02_PIG", "mass": 53630.0, "length": 468, "protein_name": "Glial fibrillary acidic protein", "gene_name": "GFAP", "organism": "Pig", "refseq_name": "glial fibrillary acidic protein isoform X1", "refseq_ac": "XP_005668766", "gene_names_uniprotkb": "GFAP", "gene_names_refseq": "GFAP", "protein_names_uniprotkb": "Glial fibrillary acidic protein", "protein_names_refseq": "glial 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chaperone-mediated autophagy", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1RR02-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A5K1VCX5-1", "uniprot_id": "A0A5K1VCX5_PIG", "mass": 130944.0, "length": 1191, "protein_name": "Calcium-transporting ATPase", "gene_name": "ATP2B3", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "ATP2B3", "gene_names_refseq": "", "protein_names_uniprotkb": "Calcium-transporting ATPase; 7.2.2.10", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-418359); (R-SSC-5578775); (R-SSC-936837)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Catalyzes the hydrolysis of ATP coupled with the transport of calcium., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, 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"ec_number_list": "", "go_molecular_function": "GO:0005516 calmodulin binding;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0016887 ATP hydrolysis activity;GO:0005388 P-type calcium transporter activity", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0005886 plasma membrane;GO:0098982 GABA-ergic synapse;GO:0098793 presynapse", "go_biological_process": "GO:0051480 regulation of cytosolic calcium ion concentration;GO:1990034 calcium ion export across plasma membrane", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A5K1VCX5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A5G2RJR4-1", "uniprot_id": "A0A5G2RJR4_PIG", "mass": 96939.0, "length": 864, "protein_name": "Tyrosine-protein kinase receptor", "gene_name": "NTRK3", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "NTRK3", "gene_names_refseq": "", "protein_names_uniprotkb": "Tyrosine-protein kinase receptor; 2.7.10.1", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-1257604); (R-SSC-388844); (R-SSC-6811558); (R-SSC-9034013); (R-SSC-9034793); (R-SSC-9603381)", "pathway_count": 6, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Receptor tyrosine kinase involved in nervous system and probably heart development. Upon binding of its ligand NTF3/neurotrophin-3, NTRK3 autophosphorylates and activates different signaling pathways, including the phosphatidylinositol 3-kinase/AKT and the MAPK pathways, that control cell survival and differentiation., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0004714 transmembrane receptor protein tyrosine kinase activity;GO:0005030 neurotrophin receptor activity;GO:0043121 neurotrophin binding;GO:0002039 p53 binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0030424 axon;GO:0043235 receptor complex", "go_biological_process": "GO:0007169 cell surface receptor protein tyrosine kinase signaling pathway;GO:0007399 nervous system development;GO:0030154 cell differentiation;GO:0048513 animal organ development;GO:0007507 heart development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A5G2RJR4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A8W4FNC0-1", "uniprot_id": "A0A8W4FNC0_PIG", "mass": 231333.0, "length": 2067, "protein_name": "Voltage-dependent L-type calcium channel subunit alpha", "gene_name": "CACNA1C", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "CACNA1C", "gene_names_refseq": "", "protein_names_uniprotkb": "Voltage-dependent L-type calcium channel subunit alpha", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Pore-forming, alpha-1C subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents. Mediates influx of calcium ions into the cytoplasm, and thereby triggers calcium release from the sarcoplasm. Plays an important role in excitation-contraction coupling in the heart. Required for normal heart development and normal regulation of heart rhythm. Required for normal contraction of smooth muscle cells in blood vessels and in the intestine. Essential for normal blood pressure regulation via its role in the contraction of arterial smooth muscle cells. Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 1, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005516 calmodulin binding;GO:0046872 metal ion binding;GO:0005245 voltage-gated calcium channel activity;GO:0051393 alpha-actinin binding;GO:0005248 voltage-gated sodium channel activity", "go_cellular_component": "GO:0030425 dendrite;GO:0043204 perikaryon;GO:0030315 T-tubule;GO:0005891 voltage-gated calcium channel complex;GO:0098839 postsynaptic density membrane", "go_biological_process": "GO:0008016 regulation of heart contraction;GO:0097553 calcium ion transmembrane import into cytosol;GO:0042391 regulation of membrane potential;GO:0007154 cell communication;GO:0023052 signaling", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A8W4FNC0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1RPY5-1", "uniprot_id": "F1RPY5_PIG", "mass": 87841.0, "length": 788, "protein_name": "Serine/threonine-protein kinase MARK2", "gene_name": "MARK2", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "MARK2", "gene_names_refseq": "", "protein_names_uniprotkb": "Serine/threonine-protein kinase MARK2; 2.7.11.1; 2.7.11.26; ELKL motif kinase 1; MAP/microtubule affinity-regulating kinase 2", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0008289 lipid binding;GO:0050321 tau-protein kinase activity;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005856 cytoskeleton;GO:0030425 dendrite;GO:0012505 endomembrane system;GO:0016328 lateral plasma membrane;GO:0005737 cytoplasm", "go_biological_process": "GO:0030154 cell differentiation;GO:0016055 Wnt signaling pathway;GO:0050770 regulation of axonogenesis;GO:0010976 positive regulation of neuron projection development;GO:0035556 intracellular signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1RPY5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A8W4F937-1", "uniprot_id": "A0A8W4F937_PIG", "mass": 21425.0, "length": 189, "protein_name": "Glial cell line-derived neurotrophic factor", "gene_name": "GDNF", "organism": "Pig", "refseq_name": "glial cell line-derived neurotrophic factor isoform X1", "refseq_ac": "XP_005672481", "gene_names_uniprotkb": "GDNF", "gene_names_refseq": "GDNF", "protein_names_uniprotkb": "Glial cell line-derived neurotrophic factor; Astrocyte-derived trophic factor", "protein_names_refseq": "glial cell line-derived neurotrophic factor isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100322894); (R-SSC-5673001); (R-SSC-8853659)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0030971 receptor tyrosine kinase binding;GO:0008083 growth factor activity;GO:0030116 glial cell-derived neurotrophic factor receptor binding;GO:0042803 protein homodimerization activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0005615 extracellular space;GO:0005794 Golgi apparatus", "go_biological_process": "GO:0043524 negative regulation of neuron apoptotic process;GO:0030182 neuron differentiation;GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis;GO:0045595 regulation of cell differentiation;GO:0009888 tissue development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A8W4F937-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A5G2R8E1-1", "uniprot_id": "A0A5G2R8E1_PIG", "mass": 112208.0, "length": 1006, "protein_name": "Protein phosphatase 1 regulatory subunit", "gene_name": "PPP1R12A", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "PPP1R12A", "gene_names_refseq": "", "protein_names_uniprotkb": "Protein phosphatase 1 regulatory subunit", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-2565942); (R-SSC-5625740); (R-SSC-5627123)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Key regulator of protein phosphatase 1C (PPP1C). Mediates binding to myosin. As part of the PPP1C complex, involved in dephosphorylation of PLK1. 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May also be involved in the regulation of gene expression., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0044877 protein-containing complex binding;GO:0017124 SH3 domain binding;GO:0019901 protein kinase binding;GO:0051015 actin filament binding;GO:0035591 signaling adaptor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005739 mitochondrion;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0005667 transcription regulator complex", "go_biological_process": "GO:0030854 positive regulation of granulocyte differentiation;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0042307 positive regulation of protein import into nucleus;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0007015 actin filament organization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A5G2RI34-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A8X9AEI7-1", "uniprot_id": "A0A8X9AEI7_PIG", "mass": 123470.0, "length": 1075, "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform", "gene_name": "PIK3CB", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "PIK3CB", "gene_names_refseq": "", "protein_names_uniprotkb": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform; 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Angiotensin II/vasopressin receptor", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (ssc:100519245)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0038023 signaling receptor activity;GO:0003725 double-stranded RNA binding;GO:0042277 peptide binding;GO:0035591 signaling adaptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0031965 nuclear membrane;GO:0061702 canonical inflammasome complex;GO:0005737 cytoplasm;GO:0140738 NLRP6 inflammasome complex", "go_biological_process": "GO:0006954 inflammatory response;GO:0007165 signal transduction;GO:0045087 innate immune response;GO:0050830 defense response to Gram-positive bacterium;GO:0051260 protein homooligomerization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A5G2RKW8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A8W4FQ32-1", "uniprot_id": "A0A8W4FQ32_PIG", "mass": 91534.0, "length": 800, "protein_name": "Cilium assembly protein DZIP1", "gene_name": "DZIP1", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "DZIP1", "gene_names_refseq": "", "protein_names_uniprotkb": "Cilium assembly protein DZIP1; DAZ-interacting zinc finger protein 1", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Molecular adapter that recruits protein complexes required for cilium assembly and function to the cilium basal body. At the exit of mitosis, localizes to the basal body and ciliary base of the forming primary cilium where it recruits and activates RAB8A to direct vesicle-mediated transport of proteins to the cilium. Also recruits the BBSome, a complex involved in cilium biogenesis, by bridging it to PCM1 at the centriolar satellites of the cilium. It is also required for the recruitment to the cilium basal body of the intraflagellar transport (IFT) machinery as well as the ciliary appendage proteins CEP164 and NINEIN. Functions as a regulator of Hedgehog signaling both through its role in cilium assembly but also probably through its ability to retain GLI3 within the cytoplasm. It is involved in spermatogenesis through its role in organization of the basal body and assembly of the sperm flagellum. Also indirectly involved in heart development through its function in ciliogenesis., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0062063 BBSome binding;GO:0060090 molecular adaptor activity;GO:0140311 protein sequestering activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005814 centriole;GO:0034451 centriolar satellite;GO:0036064 ciliary basal body", "go_biological_process": "GO:0007507 heart development;GO:0060271 cilium assembly;GO:1903566 positive regulation of protein localization to cilium;GO:0032053 ciliary basal body organization;GO:0120316 sperm flagellum assembly", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A8W4FQ32-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A5K1V0Y8-1", "uniprot_id": "A0A5K1V0Y8_PIG", "mass": 77561.0, "length": 687, "protein_name": "Transporter", "gene_name": "SLC6A6", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "SLC6A6", "gene_names_refseq": "", "protein_names_uniprotkb": "Transporter", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-352230)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0046872 metal ion binding;GO:0005369 taurine:sodium symporter activity;GO:0005332 gamma-aminobutyric acid:sodium:chloride symporter activity;GO:0022858 alanine transmembrane transporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0098982 GABA-ergic synapse;GO:0016323 basolateral plasma membrane;GO:0045211 postsynaptic membrane;GO:0016324 apical plasma membrane", "go_biological_process": "GO:0006836 neurotransmitter transport;GO:0006865 amino acid transport;GO:0050804 modulation of chemical synaptic transmission;GO:0035725 sodium ion transmembrane transport;GO:0015734 taurine transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A5K1V0Y8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1RQR2-1", "uniprot_id": "F1RQR2_PIG", "mass": 67320.0, "length": 610, "protein_name": "Menin", "gene_name": "MEN1", "organism": "Pig", "refseq_name": "menin isoform X2", "refseq_ac": "XP_005660783", "gene_names_uniprotkb": "MEN1", "gene_names_refseq": "MEN1", "protein_names_uniprotkb": "Menin", "protein_names_refseq": "menin isoform X2", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-201722); (R-SSC-2173796); (R-SSC-381426); (R-SSC-5626467); (R-SSC-8957275); (R-SSC-9772755)", "pathway_count": 6, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "A0A480V1Y9", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0003682 chromatin binding;GO:0030674 protein-macromolecule adaptor activity;GO:0051219 phosphoprotein binding;GO:0000976 transcription cis-regulatory region binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0016363 nuclear matrix;GO:0032154 cleavage furrow;GO:0000785 chromatin", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006325 chromatin organization;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006357 regulation of transcription by RNA polymerase II;GO:0008285 negative regulation of cell population proliferation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1RQR2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A5G2QRL8-1", "uniprot_id": "A0A5G2QRL8_PIG", "mass": 75821.0, "length": 666, "protein_name": "Double-strand break repair protein", "gene_name": "MRE11", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "MRE11", "gene_names_refseq": "", "protein_names_uniprotkb": "Double-strand break repair protein", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-1834949); (R-SSC-2559586); (R-SSC-5685938); (R-SSC-5685939); (R-SSC-5685942); (R-SSC-5693537); (R-SSC-5693548); (R-SSC-5693565); (R-SSC-5693568); (R-SSC-5693571); (R-SSC-5693579); (R-SSC-5693607); (R-SSC-5693616); (R-SSC-6804756); (R-SSC-69473)", "pathway_count": 15, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Core component of the MRN complex, which plays a central role in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity and meiosis. The MRN complex is involved in the repair of DNA double-strand breaks (DSBs) via homologous recombination (HR), an error-free mechanism which primarily occurs during S and G2 phases. The complex (1) mediates the end resection of damaged DNA, which generates proper single-stranded DNA, a key initial steps in HR, and is (2) required for the recruitment of other repair factors and efficient activation of ATM and ATR upon DNA damage. Within the MRN complex, MRE11 possesses both single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. MRE11 first endonucleolytically cleaves the 5' strand at DNA DSB ends to prevent non-homologous end joining (NHEJ) and licence HR. It then generates a single-stranded DNA gap via 3' to 5' exonucleolytic degradation, which is required for single-strand invasion and recombination., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008296 3'-5'-DNA exonuclease activity;GO:0030145 manganese ion binding;GO:0004520 DNA endonuclease activity;GO:0003677 DNA binding;GO:0042802 identical protein binding", "go_cellular_component": "GO:0030870 Mre11 complex;GO:0005694 chromosome;GO:0000781 chromosome, telomeric region;GO:0005737 cytoplasm;GO:0016605 PML body", "go_biological_process": "GO:0006302 double-strand break repair;GO:0051321 meiotic cell cycle;GO:0043066 negative regulation of apoptotic process;GO:0000723 telomere maintenance;GO:0006303 double-strand break repair via nonhomologous end joining", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A5G2QRL8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A5G2R5T4-1", "uniprot_id": "A0A5G2R5T4_PIG", "mass": 69439.0, "length": 606, "protein_name": "DNA repair protein Ku70", "gene_name": "XRCC6", "organism": "Pig", "refseq_name": "X-ray repair cross-complementing protein 6 isoform X1", "refseq_ac": "XP_020946599", "gene_names_uniprotkb": "XRCC6", "gene_names_refseq": "XRCC6", "protein_names_uniprotkb": "DNA repair protein Ku70; 4.2.99.18; 5'-deoxyribose-5-phosphate lyase Ku70; 5.6.2.4; ATP-dependent DNA helicase 2 subunit 1; ATP-dependent DNA helicase II 70 kDa subunit; CTC box-binding factor 75 kDa subunit; DNA repair protein XRCC6; X-ray repair cross-complementing protein 6", "protein_names_refseq": "X-ray repair cross-complementing protein 6 isoform X1", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-5693571); (R-SSC-6798695)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0016787 hydrolase activity;GO:0003684 damaged DNA binding;GO:0042162 telomeric DNA binding;GO:0003690 double-stranded DNA binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005694 chromosome;GO:0043564 Ku70:Ku80 complex;GO:0005654 nucleoplasm;GO:0005730 nucleolus", "go_biological_process": "GO:0006310 DNA recombination;GO:0006351 DNA-templated transcription;GO:0045087 innate immune response;GO:0000723 telomere maintenance;GO:0006303 double-strand break repair via nonhomologous end joining", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A5G2R5T4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A8W4FQ44-1", "uniprot_id": "A0A8W4FQ44_PIG", "mass": 34063.0, "length": 310, "protein_name": "Carbonyl reductase (NADPH)", "gene_name": "LOC110256480", "organism": "Pig", "refseq_name": "carbonyl reductase [NADPH] 1-like", "refseq_ac": "XP_020926618", "gene_names_uniprotkb": "LOC110256480", "gene_names_refseq": "LOC110256480", "protein_names_uniprotkb": "Carbonyl reductase (NADPH); 1.1.1.184", "protein_names_refseq": "carbonyl reductase [NADPH] 1-like", "tax_id": 9823, "disease": "", "pathway": " (ssc:110256480)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0047020 15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity;GO:0004090 carbonyl reductase (NADPH) activity;GO:0047021 15-hydroxyprostaglandin dehydrogenase (NADP+) activity;GO:0050221 prostaglandin E2 9-reductase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0006629 lipid metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A8W4FQ44-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A5PF08-1", "uniprot_id": "CTL4_PIG", "mass": 78480.0, "length": 707, "protein_name": "Choline transporter-like protein 4", "gene_name": "SLC44A4", "organism": "Pig", "refseq_name": "choline transporter-like protein 4", "refseq_ac": "NP_001095288", "gene_names_uniprotkb": "SLC44A4; CTL4; TPPT1", "gene_names_refseq": "C7H6orf29; CTL4; SLC44A4", "protein_names_uniprotkb": "Choline transporter-like protein 4; Solute carrier family 44 member 4; Thiamine pyrophosphate transporter 1", "protein_names_refseq": "choline transporter-like protein 4; thiamine pyrophosphate transporter 1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100124377); (R-SSC-1483191); (R-SSC-9958517)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Choline transporter that plays a role in the choline-acetylcholine system and is required to the efferent innervation of hair cells in the olivocochlear bundle for the maintenance of physiological function of outer hair cells and the protection of hair cells from acoustic injury (By similarity). Also described as a thiamine pyrophosphate transporter in colon, may mediate the absorption of microbiota-generated thiamine pyrophosphate and contribute to host thiamine (vitamin B1) homeostasis (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 8, "predicted_n_glycosites": 8, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 8, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0015297 antiporter activity;GO:0015220 choline transmembrane transporter activity;GO:0090422 thiamine pyrophosphate transmembrane transporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016324 apical plasma membrane", "go_biological_process": "GO:0030307 positive regulation of cell growth;GO:0008292 acetylcholine biosynthetic process;GO:0015871 choline transport;GO:0030974 thiamine pyrophosphate transmembrane transport;GO:0032475 otolith formation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A5PF08-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A5GFZ5-1", "uniprot_id": "DPM1_PIG", "mass": 29471.0, "length": 259, "protein_name": "Dolichol-phosphate mannosyltransferase subunit 1", "gene_name": "DPM1", "organism": "Pig", "refseq_name": "dolichol-phosphate mannosyltransferase subunit 1", "refseq_ac": "NP_001095290", "gene_names_uniprotkb": "DPM1", "gene_names_refseq": "DPM1", "protein_names_uniprotkb": "Dolichol-phosphate mannosyltransferase subunit 1; 2.4.1.83; DPM synthase subunit 1; Dolichol-phosphate mannose synthase subunit 1; Dolichyl-phosphate beta-D-mannosyltransferase subunit 1; MPD synthase subunit 1; Mannose-P-dolichol synthase subunit 1", "protein_names_refseq": "DPM synthase subunit 1; MPD synthase subunit 1; dolichol-phosphate mannose synthase subunit 1; dolichol-phosphate mannosyltransferase subunit 1; dolichyl-phosphate beta-D-mannosyltransferase subunit 1; dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit; mannose-P-dolichol synthase subunit 1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100124379); (R-SSC-162699)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins; catalytic subunit of the dolichol-phosphate mannose (DPM) synthase complex., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0033185 dolichol-phosphate-mannose synthase complex;GO:0005789 endoplasmic reticulum membrane;GO:0005783 endoplasmic reticulum;GO:0016020 membrane", "go_biological_process": "GO:0006488 dolichol-linked oligosaccharide biosynthetic process;GO:0035269 protein O-linked glycosylation via mannose;GO:0006506 GPI anchor biosynthetic process;GO:0180047 dolichol phosphate mannose biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A5GFZ5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P79384-1", "uniprot_id": "PCCB_PIG", "mass": 58590.0, "length": 539, "protein_name": "Propionyl-CoA carboxylase beta chain, mitochondrial", "gene_name": "PCCB", "organism": "Pig", "refseq_name": "propionyl-CoA carboxylase beta chain, mitochondrial precursor", "refseq_ac": "NP_999066", "gene_names_uniprotkb": "PCCB", "gene_names_refseq": "PCCB", "protein_names_uniprotkb": "Propionyl-CoA carboxylase beta chain, mitochondrial; 6.4.1.3; PCCase subunit beta; Propanoyl-CoA:carbon dioxide ligase subunit beta", "protein_names_refseq": "PCCase subunit beta; propanoyl-CoA:carbon dioxide ligase subunit beta; propionyl Coenzyme A carboxylase, beta polypeptide; propionyl-CoA carboxylase beta chain, mitochondrial precursor; propionyl-CoA carboxylase beta chain, mitochondrial; propionyl-CoA carboxylase beta subunit; propionyl-coA carboxylase B", "tax_id": 9823, "disease": "", "pathway": " (ssc:100158147)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "13752080;32543654", "class_list": "", "function": "This is one of the 2 subunits of the biotin-dependent propionyl-CoA carboxylase (PCC), a mitochondrial enzyme involved in the catabolism of odd chain fatty acids, branched-chain amino acids isoleucine, threonine, methionine, and valine and other metabolites (PubMed:13752080). Propionyl-CoA carboxylase catalyzes the carboxylation of propionyl-CoA/propanoyl-CoA to D-methylmalonyl-CoA/(S)-methylmalonyl-CoA (PubMed:13752080). Within the holoenzyme, the alpha subunit catalyzes the ATP-dependent carboxylation of the biotin carried by the biotin carboxyl carrier (BCC) domain, while the beta subunit then transfers the carboxyl group from carboxylated biotin to propionyl-CoA (By similarity). Propionyl-CoA carboxylase also significantly acts on butyryl-CoA/butanoyl-CoA, which is converted to ethylmalonyl-CoA/(2S)-ethylmalonyl-CoA at a much lower rate (PubMed:13752080). Other alternative minor substrates include (2E)-butenoyl-CoA/crotonoyl-CoA (PubMed:13752080)., [UniProtKB, UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0004658 propionyl-CoA carboxylase activity", "go_cellular_component": "GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0019626 short-chain fatty acid catabolic process;GO:0009062 fatty acid catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "P79384-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P01356-1", "uniprot_id": "CCKN_PIG", "mass": 12526.0, "length": 114, "protein_name": "Cholecystokinin", "gene_name": "CCK", "organism": "Pig", "refseq_name": "cholecystokinin precursor", "refseq_ac": "NP_999402", "gene_names_uniprotkb": "CCK", "gene_names_refseq": "CCK", "protein_names_uniprotkb": "Cholecystokinin; (1-49)-CCK58; CCK", "protein_names_refseq": "cholecystokinin precursor", "tax_id": 9823, "disease": "", "pathway": " (ssc:397468)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "25627687;27535680;30121362;32543654;5410106;6205394;8443599", "class_list": "", "function": "Cardiac expression of pro-cholecystokinin is cell-specific, which differentiates the expression from that of intestinal endocrine cells and cerebral neurons., [RefSeq, PubMed]; Haemodynamic changes seem to regulate regional proCCK expression in the mammalian heart., [RefSeq, PubMed]; This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion., [UniProtKB, UniProtKB]; We conclude that only a small fraction of neuronal CCK is nonsulfated. The intracellular distribution of nonsulfated CCK in neurons suggests that they contribute only modestly to the CCK transmitter activity., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005184 neuropeptide hormone activity;GO:0051428 peptide hormone receptor binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0030424 axon", "go_biological_process": "GO:0007409 axonogenesis;GO:0001764 neuron migration;GO:0042755 eating behavior;GO:0007586 digestion;GO:0038188 cholecystokinin signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P01356-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9MZ16-1", "uniprot_id": "VDAC1_PIG", "mass": 30727.0, "length": 283, "protein_name": "Non-selective voltage-gated ion channel VDAC1", "gene_name": "VDAC1", "organism": "Pig", "refseq_name": "non-selective voltage-gated ion channel VDAC1", "refseq_ac": "NP_999125", "gene_names_uniprotkb": "VDAC1", "gene_names_refseq": "VDAC1", "protein_names_uniprotkb": "Non-selective voltage-gated ion channel VDAC1; VDAC-1; Voltage-dependent anion-selective channel protein 1", "protein_names_refseq": "VDAC-1; non-selective voltage-gated ion channel VDAC1; voltage-dependent anion-selective channel protein 1", "tax_id": 9823, "disease": "", "pathway": " (ssc:397010); (R-SSC-5205685); (R-SSC-5689880); (R-SSC-70268)", "pathway_count": 4, "publication_count": 2, "publication_id_list": "19630752;32543654", "class_list": "", "function": "Catalyzes the scrambling of phospholipids across the outer mitochondrial membrane; the mechanism is unrelated to channel activity and is capable of translocating both anionic and zwitterionic phospholipids., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Data confirm the synthesis of VDAC1 and 2 subtypes in GV (germinal vesicle) and MII (meiosis II) stage porcine oocytes as well as their protein expression. Publication Status: Online-Only, [RefSeq, PubMed]; Non-selective voltage-gated ion channel that mediates the transport of anions and cations through the mitochondrion outer membrane and plasma membrane. The channel at the outer mitochondrial membrane allows diffusion of small hydrophilic molecules; in the plasma membrane it is involved in cell volume regulation and apoptosis. It adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective. Binds various signaling molecules, including the sphingolipid ceramide, the phospholipid phosphatidylcholine, and the sterols cholesterol and oxysterol. In depolarized mitochondria, acts downstream of PRKN and PINK1 to promote mitophagy or prevent apoptosis; polyubiquitination by PRKN promotes mitophagy, while monoubiquitination by PRKN decreases mitochondrial calcium influx which ultimately inhibits apoptosis. May participate in the formation of the permeability transition pore complex (PTPC) responsible for the release of mitochondrial products that triggers apoptosis. May mediate ATP export from cells (By similarity). Part of a complex composed of HSPA9, ITPR1 and VDAC1 that regulates mitochondrial calcium-dependent apoptosis by facilitating calcium transport from the ER lumen to the mitochondria intermembrane space thus providing calcium for the downstream calcium channel MCU that directly releases it into mitochondria matrix (By similarity). Mediates cytochrome c efflux (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008142 oxysterol binding;GO:0005524 ATP binding;GO:0005244 voltage-gated monoatomic ion channel activity;GO:0015288 porin activity;GO:0008308 voltage-gated monoatomic anion channel activity", "go_cellular_component": "GO:0005741 mitochondrial outer membrane;GO:0005886 plasma membrane;GO:0016020 membrane;GO:0045121 membrane raft;GO:0005757 mitochondrial permeability transition pore complex", "go_biological_process": "GO:0006869 lipid transport;GO:0006915 apoptotic process;GO:0036444 calcium import into the mitochondrion;GO:0006820 monoatomic anion transport;GO:0030855 epithelial cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q9MZ16-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A5G2QW31-1", "uniprot_id": "A0A5G2QW31_PIG", "mass": 148462.0, "length": 1285, "protein_name": "Unconventional myosin-VI", "gene_name": "MYO6", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "MYO6", "gene_names_refseq": "", "protein_names_uniprotkb": "Unconventional myosin-VI; Unconventional myosin-6", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-190873); (R-SSC-399719); (R-SSC-9013418); (R-SSC-9013420); (R-SSC-9013422)", "pathway_count": 5, "publication_count": 3, "publication_id_list": "22940248;25936506;32543654", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005516 calmodulin binding;GO:0005524 ATP binding;GO:0051015 actin filament binding;GO:0003774 cytoskeletal motor activity;GO:0000146 microfilament motor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005794 Golgi apparatus;GO:0005829 cytosol;GO:0005905 clathrin-coated pit;GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "GO:0006897 endocytosis;GO:0015031 protein transport;GO:0007605 sensory perception of sound;GO:0042491 inner ear auditory receptor cell differentiation;GO:0007015 actin filament organization", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A5G2QW31-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A8W4FFA1-1", "uniprot_id": "A0A8W4FFA1_PIG", "mass": 144748.0, "length": 1246, "protein_name": "Structural maintenance of chromosomes protein", "gene_name": "SMC3", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "SMC3", "gene_names_refseq": "", "protein_names_uniprotkb": "Structural maintenance of chromosomes protein", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-2467813); (R-SSC-2468052); (R-SSC-2470946); (R-SSC-2500257); (R-SSC-3108214)", "pathway_count": 5, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Central component of cohesin, a complex required for chromosome cohesion during the cell cycle. The cohesin complex may form a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. Cohesion is coupled to DNA replication and is involved in DNA repair. The cohesin complex also plays an important role in spindle pole assembly during mitosis and in chromosomes movement., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0003682 chromatin binding;GO:0046982 protein heterodimerization activity;GO:0003690 double-stranded DNA binding", "go_cellular_component": "GO:0031981 nuclear lumen;GO:0000775 chromosome, centromeric region;GO:0030892 mitotic cohesin complex;GO:0030893 meiotic cohesin complex;GO:0005654 nucleoplasm", "go_biological_process": "GO:0006281 DNA repair;GO:0051321 meiotic cell cycle;GO:0051276 chromosome organization;GO:0051301 cell division;GO:0090307 mitotic spindle assembly", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A8W4FFA1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A5G2R8T3-1", "uniprot_id": "A0A5G2R8T3_PIG", "mass": 128168.0, "length": 1116, "protein_name": "Myosin IE", "gene_name": "MYO1E", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "MYO1E", "gene_names_refseq": "", "protein_names_uniprotkb": "Myosin IE", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003779 actin binding;GO:0005516 calmodulin binding;GO:0005524 ATP binding;GO:0003774 cytoskeletal motor activity;GO:0051015 actin filament binding", "go_cellular_component": "GO:0016459 myosin complex;GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0005903 brush border;GO:0005912 adherens junction", "go_biological_process": "GO:0006897 endocytosis;GO:0007015 actin filament organization;GO:0032835 glomerulus development;GO:0003094 glomerular filtration;GO:0072015 podocyte development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A5G2R8T3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SEC0-1", "uniprot_id": "DCTN3_PIG", "mass": 21166.0, "length": 186, "protein_name": "Dynactin subunit 3", "gene_name": "DCTN3", "organism": "Pig", "refseq_name": "dynactin subunit 3", "refseq_ac": "XP_003130704", "gene_names_uniprotkb": "DCTN3", "gene_names_refseq": "DCTN3", "protein_names_uniprotkb": "Dynactin subunit 3", "protein_names_refseq": "dynactin subunit 3", "tax_id": 9823, "disease": "", "pathway": " (ssc:100521815); (R-SSC-2132295); (R-SSC-2565942); (R-SSC-3371497); (R-SSC-380259); (R-SSC-380270); (R-SSC-380284); (R-SSC-380320); (R-SSC-5620912); (R-SSC-6807878); (R-SSC-8854518)", "pathway_count": 11, "publication_count": 4, "publication_id_list": "30723633;32543654;33734450;36071160", "class_list": "", "function": "Part of the dynactin complex that activates the molecular motor dynein for ultra-processive transport along microtubules (PubMed:33734450, PubMed:36071160). Together with dynein is involved in spindle assembly and cytokinesis (By similarity)., [UniProtKB, PubMed, PubMed, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005813 centrosome;GO:0005819 spindle;GO:0032154 cleavage furrow;GO:0005869 dynactin complex", "go_biological_process": "GO:0061640 cytoskeleton-dependent cytokinesis;GO:0007017 microtubule-based process", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "F1SEC0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A8W4FG96-1", "uniprot_id": "A0A8W4FG96_PIG", "mass": 41453.0, "length": 358, "protein_name": "Mitogen-activated protein kinase", "gene_name": "MAPK1", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "MAPK1", "gene_names_refseq": "", "protein_names_uniprotkb": "Mitogen-activated protein kinase; 2.7.11.24", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-111995); (R-SSC-112409); (R-SSC-112411); (R-SSC-1181150); (R-SSC-1295596); (R-SSC-1502540); (R-SSC-162658); (R-SSC-170968); (R-SSC-198753); (R-SSC-202670); (R-SSC-2029482); (R-SSC-2173795); (R-SSC-2173796); (R-SSC-2559580); (R-SSC-2559582); (R-SSC-2559585); (R-SSC-2871796); (R-SSC-3371453); (R-SSC-375165); (R-SSC-437239); (R-SSC-445144); (R-SSC-450341); (R-SSC-456926); (R-SSC-5654726); (R-SSC-5654733); (R-SSC-5663213); (R-SSC-5668599); (R-SSC-5673001); (R-SSC-5674135); (R-SSC-5674499); (R-SSC-5675221); (R-SSC-6798695); (R-SSC-6811558); (R-SSC-74749); (R-SSC-877300); (R-SSC-881907); (R-SSC-8939211); (R-SSC-9627069); (R-SSC-9634635); (R-SSC-9634638); (R-SSC-9732724); (R-SSC-982772); (R-SSC-9856649)", "pathway_count": 43, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Acts as a transcriptional repressor. Binds to a [GC]AAA[GC] consensus sequence. Repress the expression of interferon gamma-induced genes. Seems to bind to the promoter of CCL5, DMP1, IFIH1, IFITM1, IRF7, IRF9, LAMP3, OAS1, OAS2, OAS3 and STAT1. Transcriptional activity is independent of kinase activity., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0004707 MAP kinase activity;GO:0106310 protein serine kinase activity;GO:0004674 protein serine/threonine kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005901 caveola;GO:0005813 centrosome;GO:0005819 spindle", "go_biological_process": "GO:0003006 developmental process involved in reproduction;GO:0051707 response to other organism;GO:0006952 defense response;GO:0048468 cell development;GO:0048513 animal organ development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A8W4FG96-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A5G2QQD0-1", "uniprot_id": "A0A5G2QQD0_PIG", "mass": 13693.0, "length": 119, "protein_name": "Stromal cell-derived factor 1", "gene_name": "CXCL12", "organism": "Pig", "refseq_name": "stromal cell-derived factor 1 isoform 2 precursor", "refseq_ac": "NP_001422149", "gene_names_uniprotkb": "CXCL12", "gene_names_refseq": "CXCL12; SDF-1", "protein_names_uniprotkb": "Stromal cell-derived factor 1; C-X-C motif chemokine 12", "protein_names_refseq": "CXC chemokine; CXCL12 chemokine; chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1); stromal cell-derived factor 1 isoform 2 precursor", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-380108); (R-SSC-418594)", "pathway_count": 2, "publication_count": 5, "publication_id_list": "21667240;22146760;29945222;31955063;32543654", "class_list": "", "function": "Expression and function of the stromal cell-derived factor-1 (SDF-1) and CXC chemokine receptor 4 (CXCR4) in the swine ovarian follicle., [RefSeq, PubMed]; Polymorphisms in CXCL12 are significantly associated with immunological traits in Landrace piglets and have potential application value for marker-assisted selection of pig breeding with disease resistance., [RefSeq, PubMed]; The new method has shown to be capable of promoting CSCs proliferation and differentiation into cardiomyocytes through activating the SDF-1/CXCR4 axis, while inhibiting myocardial apoptosis , thereby enhancing myocardial regeneration., [RefSeq, PubMed]; These results suggest that CXCL12 may be critical for the establishment of pregnancy by regulating trophoblast migration and T cell recruitment into the endometrium during the implantation period in pigs., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008083 growth factor activity;GO:0008009 chemokine activity;GO:0005178 integrin binding;GO:0045236 CXCR chemokine receptor binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0009897 external side of plasma membrane", "go_biological_process": "GO:0006952 defense response;GO:0006955 immune response;GO:0030335 positive regulation of cell migration;GO:0090280 positive regulation of calcium ion import;GO:0050921 positive regulation of chemotaxis", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "A0A5G2QQD0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1RH38-1", "uniprot_id": "F1RH38_PIG", "mass": 50226.0, "length": 457, "protein_name": "Nuclear receptor subfamily 1 group H member 2", "gene_name": "NR1H2", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "NR1H2", "gene_names_refseq": "", "protein_names_uniprotkb": "Nuclear receptor subfamily 1 group H member 2", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-383280); (R-SSC-4090294); (R-SSC-8866427); (R-SSC-9029569); (R-SSC-9623433)", "pathway_count": 5, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0004879 nuclear receptor activity;GO:0034191 apolipoprotein A-I receptor binding;GO:0051117 ATPase binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0090575 RNA polymerase II transcription regulator complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006629 lipid metabolic process;GO:0048550 negative regulation of pinocytosis;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0010875 positive regulation of cholesterol efflux", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1RH38-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A8W4FGI7-1", "uniprot_id": "A0A8W4FGI7_PIG", "mass": 32751.0, "length": 298, "protein_name": "DNA excision repair protein ERCC-1", "gene_name": "ERCC1", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "ERCC1", "gene_names_refseq": "", "protein_names_uniprotkb": "DNA excision repair protein ERCC-1", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-5685938); (R-SSC-5696395); (R-SSC-5696400); (R-SSC-6782135); (R-SSC-6783310)", "pathway_count": 5, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Non-catalytic component of a structure-specific DNA repair endonuclease responsible for the 5'-incision during DNA repair. Responsible, in conjunction with SLX4, for the first step in the repair of interstrand cross-links (ICL). Participates in the processing of anaphase bridge-generating DNA structures, which consist in incompletely processed DNA lesions arising during S or G2 phase, and can result in cytokinesis failure. Also required for homology-directed repair (HDR) of DNA double-strand breaks, in conjunction with SLX4., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003684 damaged DNA binding;GO:0001094 TFIID-class transcription factor complex binding;GO:0003697 single-stranded DNA binding;GO:1990841 promoter-specific chromatin binding;GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity", "go_cellular_component": "GO:0005634 nucleus;GO:0000110 nucleotide-excision repair factor 1 complex;GO:0070522 ERCC4-ERCC1 complex;GO:0005654 nucleoplasm;GO:0000781 chromosome, telomeric region", "go_biological_process": "GO:0032204 regulation of telomere maintenance;GO:0006310 DNA recombination;GO:0000723 telomere maintenance;GO:0006302 double-strand break repair;GO:0006289 nucleotide-excision repair", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A8W4FGI7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A5G2R3T9-1", "uniprot_id": "A0A5G2R3T9_PIG", "mass": 109360.0, "length": 973, "protein_name": "Serine/threonine-protein kinase/endoribonuclease IRE1", "gene_name": "ERN1", "organism": "Pig", "refseq_name": "serine/threonine-protein kinase/endoribonuclease IRE1", "refseq_ac": "XP_005668752", "gene_names_uniprotkb": "ERN1", "gene_names_refseq": "ERN1", "protein_names_uniprotkb": "Serine/threonine-protein kinase/endoribonuclease IRE1; 2.7.11.1; Endoplasmic reticulum-to-nucleus signaling 1; Inositol-requiring protein 1; Ire1-alpha", "protein_names_refseq": "serine/threonine-protein kinase/endoribonuclease IRE1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100510978)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0004521 RNA endonuclease activity;GO:0005161 platelet-derived growth factor receptor binding;GO:0000287 magnesium ion binding", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane;GO:1990604 IRE1-TRAF2-ASK1 complex;GO:1990630 IRE1-RACK1-PP2A complex;GO:0005739 mitochondrion;GO:0005886 plasma membrane", "go_biological_process": "GO:0006397 mRNA processing;GO:0030968 endoplasmic reticulum unfolded protein response;GO:0033120 positive regulation of RNA splicing;GO:0070054 mRNA splicing, via endonucleolytic cleavage and ligation;GO:1901142 insulin metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A5G2R3T9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1RFM6-1", "uniprot_id": "F1RFM6_PIG", "mass": 70795.0, "length": 633, "protein_name": "Eukaryotic translation initiation factor 2-alpha kinase 1", "gene_name": "EIF2AK1", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "EIF2AK1", "gene_names_refseq": "", "protein_names_uniprotkb": "Eukaryotic translation initiation factor 2-alpha kinase 1; 2.7.11.1; Heme-regulated eukaryotic initiation factor eIF-2-alpha kinase; Hemin-sensitive initiation factor 2-alpha kinase", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (ssc:100514518); (R-SSC-9840373)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity;GO:0042803 protein homodimerization activity;GO:0020037 heme binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0006950 response to stress;GO:0017148 negative regulation of translation;GO:0070585 protein localization to mitochondrion;GO:1901526 positive regulation of mitophagy;GO:0008285 negative regulation of cell population proliferation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1RFM6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A5G2R4L4-1", "uniprot_id": "A0A5G2R4L4_PIG", "mass": 75249.0, "length": 667, "protein_name": "E3 ubiquitin-protein ligase Midline-1", "gene_name": "MID1", "organism": "Pig", "refseq_name": "E3 ubiquitin-protein ligase Midline-1 isoform X1", "refseq_ac": "XP_003134970", "gene_names_uniprotkb": "MID1", "gene_names_refseq": "MID1", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase Midline-1; 2.3.2.27; RING finger protein Midline-1; RING-type E3 ubiquitin transferase Midline-1; Tripartite motif-containing protein 18", "protein_names_refseq": "E3 ubiquitin-protein ligase Midline-1 isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100524415)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Has E3 ubiquitin ligase activity towards IGBP1, promoting its monoubiquitination, which results in deprotection of the catalytic subunit of protein phosphatase PP2A, and its subsequent degradation by polyubiquitination., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8D1YVQ6", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0016740 transferase activity;GO:0008017 microtubule binding;GO:0042803 protein homodimerization activity;GO:0031625 ubiquitin protein ligase binding", "go_cellular_component": "GO:0005874 microtubule;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005881 cytoplasmic microtubule", "go_biological_process": "GO:0070507 regulation of microtubule cytoskeleton organization;GO:0032874 positive regulation of stress-activated MAPK cascade;GO:0035372 protein localization to microtubule", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A5G2R4L4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A5GFY8-1", "uniprot_id": "SERA_PIG", "mass": 56810.0, "length": 533, "protein_name": "D-3-phosphoglycerate dehydrogenase", "gene_name": "PHGDH", "organism": "Pig", "refseq_name": "D-3-phosphoglycerate dehydrogenase", "refseq_ac": "NP_001116634", "gene_names_uniprotkb": "PHGDH", "gene_names_refseq": "PHGDH", "protein_names_uniprotkb": "D-3-phosphoglycerate dehydrogenase; 1.1.1.37; 1.1.1.399; 1.1.1.95; 2-oxoglutarate reductase; 3-PGDH; Malate dehydrogenase", "protein_names_refseq": "2-oxoglutarate reductase; 3-PGDH; D-3-phosphoglycerate dehydrogenase; malate dehydrogenase", "tax_id": 9823, "disease": "", "pathway": " (ssc:100144529); (R-SSC-977347)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate and the reversible oxidation of (S)-malate to oxaloacetate., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0051287 NAD binding;GO:0004617 phosphoglycerate dehydrogenase activity;GO:0030060 L-malate dehydrogenase (NAD+) activity", "go_cellular_component": "", "go_biological_process": "GO:0006564 L-serine biosynthetic process;GO:0008652 amino acid biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A5GFY8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1RGL0-1", "uniprot_id": "F1RGL0_PIG", "mass": 32032.0, "length": 284, "protein_name": "HCLS1-associated protein X-1", "gene_name": "HAX1", "organism": "Pig", "refseq_name": "HCLS1-associated protein X-1 isoform X2", "refseq_ac": "XP_020945452", "gene_names_uniprotkb": "HAX1", "gene_names_refseq": "HAX1", "protein_names_uniprotkb": "HCLS1-associated protein X-1; HS1-associating protein X-1", "protein_names_refseq": "HCLS1-associated protein X-1 isoform X2", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Recruits the Arp2/3 complex to the cell cortex and regulates reorganization of the cortical actin cytoskeleton via its interaction with KCNC3 and the Arp2/3 complex. Slows down the rate of inactivation of KCNC3 channels. Promotes GNA13-mediated cell migration. Involved in the clathrin-mediated endocytosis pathway. May be involved in internalization of ABC transporters such as ABCB11. May inhibit CASP9 and CASP3. Promotes cell survival. May regulate intracellular calcium pools., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0019966 interleukin-1 binding;GO:0035591 signaling adaptor activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0031965 nuclear membrane;GO:0031410 cytoplasmic vesicle;GO:0016529 sarcoplasmic reticulum;GO:0005741 mitochondrial outer membrane", "go_biological_process": "GO:0043066 negative regulation of apoptotic process;GO:0030854 positive regulation of granulocyte differentiation;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0051897 positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction;GO:0038158 granulocyte colony-stimulating factor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1RGL0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A5G2RIA8-1", "uniprot_id": "A0A5G2RIA8_PIG", "mass": 54524.0, "length": 483, "protein_name": "Vitamin K-dependent protein C", "gene_name": "PROC", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "PROC", "gene_names_refseq": "", "protein_names_uniprotkb": "Vitamin K-dependent protein C; 3.4.21.69; Anticoagulant protein C; Autoprothrombin IIA; Blood coagulation factor XIV", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-159740); (R-SSC-159763); (R-SSC-159782); (R-SSC-202733); (R-SSC-381426); (R-SSC-8957275); (R-SSC-9769733); (R-SSC-9769739); (R-SSC-9769743)", "pathway_count": 9, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Protein C is a vitamin K-dependent serine protease that regulates blood coagulation by inactivating factors Va and VIIIa in the presence of calcium ions and phospholipids. Exerts a protective effect on the endothelial cell barrier function., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004252 serine-type endopeptidase activity;GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0005615 extracellular space", "go_biological_process": "GO:0006508 proteolysis;GO:0007596 blood coagulation;GO:0050819 negative regulation of coagulation;GO:0043066 negative regulation of apoptotic process;GO:0050728 negative regulation of inflammatory response", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A5G2RIA8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A5K1VSC0-1", "uniprot_id": "A0A5K1VSC0_PIG", "mass": 54215.0, "length": 498, "protein_name": "Wiskott-Aldrich syndrome protein family member", "gene_name": "WASF2", "organism": "Pig", "refseq_name": "actin-binding protein WASF2", "refseq_ac": "NP_001245373", "gene_names_uniprotkb": "WASF2", "gene_names_refseq": "WASF2", "protein_names_uniprotkb": "Wiskott-Aldrich syndrome protein family member; WASP family protein member", "protein_names_refseq": "WAS protein family member 2; actin-binding protein WASF2", "tax_id": 9823, "disease": "", "pathway": " (ssc:100512789); (R-SSC-2029482); (R-SSC-4420097); (R-SSC-5663213); (R-SSC-9013149); (R-SSC-9013404); (R-SSC-9013423)", "pathway_count": 7, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003779 actin binding;GO:0017124 SH3 domain binding;GO:0034237 protein kinase A regulatory subunit binding;GO:0071933 Arp2/3 complex binding", "go_cellular_component": "GO:0005856 cytoskeleton;GO:0005769 early endosome;GO:0005911 cell-cell junction;GO:0030027 lamellipodium;GO:0045202 synapse", "go_biological_process": "GO:0030036 actin cytoskeleton organization;GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation;GO:0098974 postsynaptic actin cytoskeleton organization;GO:0010592 positive regulation of lamellipodium assembly;GO:0051497 negative regulation of stress fiber assembly", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A5K1VSC0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A8W4FMZ5-1", "uniprot_id": "A0A8W4FMZ5_PIG", "mass": 109559.0, "length": 950, "protein_name": "Ubiquitin carboxyl-terminal hydrolase", "gene_name": "USP15", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "USP15", "gene_names_refseq": "", "protein_names_uniprotkb": "Ubiquitin carboxyl-terminal hydrolase; 3.4.19.12", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-5689880)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004843 cysteine-type deubiquitinase activity;GO:0061649 ubiquitin-modified histone reader activity;GO:0005160 transforming growth factor beta receptor binding;GO:0046332 SMAD binding;GO:0004197 cysteine-type endopeptidase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0016604 nuclear body", "go_biological_process": "GO:0006508 proteolysis;GO:0016579 protein deubiquitination;GO:0051252 regulation of RNA metabolic process;GO:1905035 negative regulation of antifungal innate immune response;GO:0007179 transforming growth factor beta receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A8W4FMZ5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A8W4FDT9-1", "uniprot_id": "A0A8W4FDT9_PIG", "mass": 187451.0, "length": 1665, "protein_name": "Complement C3", "gene_name": "C3", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "C3", "gene_names_refseq": "", "protein_names_uniprotkb": "Complement C3", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-173736); (R-SSC-174577); (R-SSC-198933); (R-SSC-375276); (R-SSC-381426); (R-SSC-6798695); (R-SSC-8957275); (R-SSC-977606)", "pathway_count": 8, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Acts as a chemoattractant for neutrophils in chronic inflammation., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Adipogenic hormone that stimulates triglyceride synthesis and glucose transport in adipocytes, regulating fat storage and playing a role in postprandial triglyceride clearance. Appears to stimulate triglyceride synthesis via activation of the PLC, MAPK and AKT signaling pathways. Acts by binding to its receptor, C5AR2, activating G protein-coupled receptor signaling, promoting the phosphorylation, ARRB2-mediated internalization and endocytosis of C5AR2. In contrast to C3a anaphylatoxin peptide, does not show pro-inflammatory activity., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Mediator of local inflammatory process released following cleavage by C3 convertase. Acts by binding to its receptor, C3AR1, activating G protein-coupled receptor signaling, promoting the phosphorylation, ARRB2-mediated internalization and endocytosis of C3AR1. C3a anaphylatoxin stimulates the activation of immune cells such as mast cells and basophilic leukocytes to release inflammation agents, such as cytokines, chemokines and histamine, which promote inflammation development. Also acts as potent chemoattractant for the migration of macrophages and neutrophils to the inflamed tissues, resulting in neutralization of the inflammatory triggers by multiple ways, such as phagocytosis and generation of reactive oxidants., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Non-enzymatic component of C5 convertase. Generated following cleavage by C3 convertase, it covalently attaches to the surface of pathogens, where it acts as an opsonin that marks the surface of antigens for removal. Complement C3b binds covalently via its reactive thioester, to cell surface carbohydrates or immune aggregates. Together with complement C4b, it then recruits the serine protease complement C2b to form the C5 convertase, which cleaves and activate C5, the next component of the complement pathways. In the alternative complement pathway, recruits the serine protease CFB to form the C5 convertase that cleaves and activates C5., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Precursor of non-enzymatic components of the classical, alternative, lectin and GZMK complement pathways, which consist in a cascade of proteins that leads to phagocytosis and breakdown of pathogens and signaling that strengthens the adaptive immune system., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004866 endopeptidase inhibitor activity;GO:0048018 receptor ligand activity;GO:0031715 C5L2 anaphylatoxin chemotactic receptor binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0009986 cell surface;GO:0032991 protein-containing complex", "go_biological_process": "GO:0006954 inflammatory response;GO:0006958 complement activation, classical pathway;GO:0006957 complement activation, alternative pathway;GO:0006631 fatty acid metabolic process;GO:0002430 complement receptor mediated signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A8W4FDT9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1RF44-1", "uniprot_id": "F1RF44_PIG", "mass": 54809.0, "length": 509, "protein_name": "Solute carrier family 2, facilitated glucose transporter member 4", "gene_name": "SLC2A4", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "SLC2A4", "gene_names_refseq": "", "protein_names_uniprotkb": "Solute carrier family 2, facilitated glucose transporter member 4; Glucose transporter type 4, insulin-responsive", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-189200)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Insulin-regulated facilitative glucose transporter, which plays a key role in removal of glucose from circulation. Response to insulin is regulated by its intracellular localization: in the absence of insulin, it is efficiently retained intracellularly within storage compartments in muscle and fat cells. Upon insulin stimulation, translocates from these compartments to the cell surface where it transports glucose from the extracellular milieu into the cell., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0055056 D-glucose transmembrane transporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0048471 perinuclear region of cytoplasm;GO:0005768 endosome;GO:0005829 cytosol;GO:0045121 membrane raft", "go_biological_process": "GO:1904659 D-glucose transmembrane transport;GO:0032869 cellular response to insulin stimulus;GO:0070837 dehydroascorbic acid transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1RF44-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A5K1UGB8-1", "uniprot_id": "A0A5K1UGB8_PIG", "mass": 61330.0, "length": 568, "protein_name": "Glutathione hydrolase", "gene_name": "GGT1", "organism": "Pig", "refseq_name": "gamma-glutamyltranspeptidase 1 isoform X1", "refseq_ac": "XP_005670939", "gene_names_uniprotkb": "GGT1", "gene_names_refseq": "GGT1", "protein_names_uniprotkb": "Glutathione hydrolase; 2.3.2.2; 3.4.19.13; Gamma-glutamyltransferase; Gamma-glutamyltranspeptidase", "protein_names_refseq": "gamma-glutamyltranspeptidase 1 isoform X1", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-174403); (R-SSC-2142691); (R-SSC-5423646); (R-SSC-9753281)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0036374 glutathione hydrolase activity;GO:0103068 leukotriene C4 gamma-glutamyl transferase activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0031982 vesicle;GO:0016020 membrane", "go_biological_process": "GO:0006751 glutathione catabolic process;GO:0006750 glutathione biosynthetic process;GO:0002682 regulation of immune system process;GO:0050727 regulation of inflammatory response;GO:0019344 cysteine biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A5K1UGB8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1RI57-1", "uniprot_id": "F1RI57_PIG", "mass": 41570.0, "length": 376, "protein_name": "Beta-1,3-N-acetylglucosaminyltransferase", "gene_name": "LFNG", "organism": "Pig", "refseq_name": "beta-1,3-N-acetylglucosaminyltransferase lunatic fringe", "refseq_ac": "XP_020941653", "gene_names_uniprotkb": "LFNG", "gene_names_refseq": "LFNG", "protein_names_uniprotkb": "Beta-1,3-N-acetylglucosaminyltransferase; 2.4.1.222; O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase", "protein_names_refseq": "beta-1,3-N-acetylglucosaminyltransferase lunatic fringe", "tax_id": 9823, "disease": "", "pathway": " (ssc:100524978)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0046872 metal ion binding;GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity", "go_cellular_component": "GO:0000139 Golgi membrane", "go_biological_process": "GO:0007389 pattern specification process;GO:0014807 regulation of somitogenesis;GO:0030217 T cell differentiation;GO:0002315 marginal zone B cell differentiation;GO:1902367 negative regulation of Notch signaling pathway involved in somitogenesis", "synthesized_glycan_count": 19, "hit_score": 0.2, "record_id": "F1RI57-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1RN84-1", "uniprot_id": "F1RN84_PIG", "mass": 116044.0, "length": 1001, "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "TAOK1", "organism": "Pig", "refseq_name": "serine/threonine-protein kinase TAO1", "refseq_ac": "XP_003483123", "gene_names_uniprotkb": "TAOK1", "gene_names_refseq": "TAOK1", "protein_names_uniprotkb": "non-specific serine/threonine protein kinase; 2.7.11.1", "protein_names_refseq": "serine/threonine-protein kinase TAO1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100622172); (R-SSC-141430); (R-SSC-141444); (R-SSC-2467813); (R-SSC-2500257); (R-SSC-5663220); (R-SSC-68877); (R-SSC-9648025)", "pathway_count": 8, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A4X1TUA5", "ec_number_list": "", "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0048487 beta-tubulin binding;GO:0043014 alpha-tubulin binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0048471 perinuclear region of cytoplasm;GO:0015630 microtubule cytoskeleton", "go_biological_process": "GO:0006281 DNA repair;GO:0046330 positive regulation of JNK cascade;GO:0070050 neuron cellular homeostasis;GO:0097194 execution phase of apoptosis;GO:0007026 negative regulation of microtubule depolymerization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1RN84-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A5G2QV47-1", "uniprot_id": "A0A5G2QV47_PIG", "mass": 40686.0, "length": 356, "protein_name": "Aprataxin", "gene_name": "APTX", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "APTX", "gene_names_refseq": "", "protein_names_uniprotkb": "Aprataxin; 3.6.1.71; 3.6.1.72; Forkhead-associated domain histidine triad-like protein", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "DNA-binding protein involved in single-strand DNA break repair, double-strand DNA break repair and base excision repair. Resolves abortive DNA ligation intermediates formed either at base excision sites, or when DNA ligases attempt to repair non-ligatable breaks induced by reactive oxygen species. Catalyzes the release of adenylate groups covalently linked to 5'-phosphate termini, resulting in the production of 5'-phosphate termini that can be efficiently rejoined. Also able to hydrolyze adenosine 5'-monophosphoramidate (AMP-NH(2)) and diadenosine tetraphosphate (AppppA), but with lower catalytic activity. Likewise, catalyzes the release of 3'-linked guanosine (DNAppG) and inosine (DNAppI) from DNA, but has higher specific activity with 5'-linked adenosine (AppDNA)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A287BBF0", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0033699 DNA 5'-adenosine monophosphate hydrolase activity;GO:0120108 DNA-3'-diphospho-5'-guanosine diphosphatase activity;GO:0003682 chromatin binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005634 nucleus;GO:0000785 chromatin", "go_biological_process": "GO:0000012 single strand break repair;GO:0006281 DNA repair;GO:0031647 regulation of protein stability", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A5G2QV47-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A5G2QWP0-1", "uniprot_id": "A0A5G2QWP0_PIG", "mass": 212288.0, "length": 1926, "protein_name": "Plexin-D1", "gene_name": "PLXND1", "organism": "Pig", "refseq_name": "plexin-D1 isoform X2", "refseq_ac": "XP_020925024", "gene_names_uniprotkb": "PLXND1", "gene_names_refseq": "PLXND1", "protein_names_uniprotkb": "Plexin-D1", "protein_names_refseq": "plexin-D1 isoform X2", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-416700); (R-SSC-9696270)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0017154 semaphorin receptor activity;GO:0019904 protein domain specific binding", "go_cellular_component": "GO:0031258 lamellipodium membrane;GO:0098978 glutamatergic synapse;GO:0002116 semaphorin receptor complex;GO:0005886 plasma membrane;GO:0030424 axon", "go_biological_process": "GO:0001525 angiogenesis;GO:0003151 outflow tract morphogenesis;GO:0007162 negative regulation of cell adhesion;GO:0071526 semaphorin-plexin signaling pathway;GO:0043524 negative regulation of neuron apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A5G2QWP0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A5G2QNL8-1", "uniprot_id": "A0A5G2QNL8_PIG", "mass": 109062.0, "length": 971, "protein_name": "Mast/stem cell growth factor receptor", "gene_name": "KIT", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "KIT", "gene_names_refseq": "", "protein_names_uniprotkb": "Mast/stem cell growth factor receptor; 2.7.10.1", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-1257604); (R-SSC-1433557); (R-SSC-1433559); (R-SSC-5673001); (R-SSC-6811558); (R-SSC-9856649)", "pathway_count": 6, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0019838 growth factor binding;GO:0046872 metal ion binding;GO:0004714 transmembrane receptor protein tyrosine kinase activity;GO:0019955 cytokine binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0043235 receptor complex;GO:0005615 extracellular space;GO:0005911 cell-cell junction;GO:0009897 external side of plasma membrane", "go_biological_process": "GO:0050793 regulation of developmental process;GO:0038093 Fc receptor signaling pathway;GO:0006935 chemotaxis;GO:0008284 positive regulation of cell population proliferation;GO:0016477 cell migration", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A5G2QNL8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A5G2QYA9-1", "uniprot_id": "A0A5G2QYA9_PIG", "mass": 56665.0, "length": 507, "protein_name": "Peptidase M20 domain containing 1", "gene_name": "PM20D1", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "PM20D1", "gene_names_refseq": "", "protein_names_uniprotkb": "Peptidase M20 domain containing 1", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Secreted enzyme that regulates the endogenous N-fatty acyl amino acid (NAAs) tissue and circulating levels by functioning as a bidirectional NAA synthase/hydrolase. It condenses free fatty acids and free amino acids to generate NAAs and bidirectionally catalyzes the reverse hydrolysis reaction. Some of these NAAs stimulate oxidative metabolism via mitochondrial uncoupling, increasing energy expenditure in a UPC1-independent manner. Thereby, this secreted protein may indirectly regulate whole body energy expenditure. PM20D1 circulates in tight association with both low- and high-density (LDL and HDL,respectively) lipoprotein particles., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004046 aminoacylase activity;GO:0046872 metal ion binding;GO:0008233 peptidase activity;GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "GO:0006508 proteolysis;GO:0006629 lipid metabolic process;GO:0043604 amide biosynthetic process;GO:0043605 amide catabolic process;GO:1990845 adaptive thermogenesis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A5G2QYA9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A5G2QPA8-1", "uniprot_id": "A0A5G2QPA8_PIG", "mass": 41632.0, "length": 388, "protein_name": "NAD(P)H-hydrate epimerase", "gene_name": "NAXE", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "NAXE; AIBP; APOA1BP", "gene_names_refseq": "", "protein_names_uniprotkb": "NAD(P)H-hydrate epimerase; 5.1.99.6; AI-BP; Apolipoprotein A-I-binding protein; NAD(P)HX epimerase", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-196807)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX. Accelerates cholesterol efflux from endothelial cells to high-density lipoprotein (HDL) and thereby regulates angiogenesis., [UniProtKB, HAMAP, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0042802 identical protein binding;GO:0046872 metal ion binding;GO:0000166 nucleotide binding;GO:0052856 NAD(P)HX epimerase activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005739 mitochondrion;GO:0005829 cytosol;GO:0005929 cilium;GO:0044297 cell body", "go_biological_process": "GO:0006869 lipid transport;GO:0016525 negative regulation of angiogenesis;GO:0002040 sprouting angiogenesis;GO:0010874 regulation of cholesterol efflux;GO:0046496 nicotinamide nucleotide metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A5G2QPA8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A5G2R267-1", "uniprot_id": "A0A5G2R267_PIG", "mass": 27051.0, "length": 241, "protein_name": "Methylthioribulose-1-phosphate dehydratase", "gene_name": "APIP", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "APIP", "gene_names_refseq": "", "protein_names_uniprotkb": "Methylthioribulose-1-phosphate dehydratase; 4.2.1.109; APAF1-interacting protein; MTRu-1-P dehydratase", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-111458); (R-SSC-9627069)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway, which plays a key role in cancer, apoptosis, microbial proliferation and inflammation. May inhibit the CASP1-related inflammatory response (pyroptosis), the CASP9-dependent apoptotic pathway and the cytochrome c-dependent and APAF1-mediated cell death., [UniProtKB, HAMAP, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0046872 metal ion binding;GO:0016829 lyase activity;GO:0008270 zinc ion binding;GO:0042802 identical protein binding;GO:0046570 methylthioribulose 1-phosphate dehydratase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0019509 L-methionine salvage from methylthioadenosine;GO:0043066 negative regulation of apoptotic process;GO:0051289 protein homotetramerization;GO:0006915 apoptotic process;GO:0070269 pyroptotic inflammatory response", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A5G2R267-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A5G2QQU6-1", "uniprot_id": "A0A5G2QQU6_PIG", "mass": 77797.0, "length": 683, "protein_name": "Protein kinase C eta type", "gene_name": "PRKCH", "organism": "Pig", "refseq_name": "protein kinase C eta type", "refseq_ac": "XP_020918137", "gene_names_uniprotkb": "PRKCH", "gene_names_refseq": "PRKCH", "protein_names_uniprotkb": "Protein kinase C eta type; 2.7.11.13; PKC-L; nPKC-eta", "protein_names_refseq": "protein kinase C eta type", "tax_id": 9823, "disease": "", "pathway": " (ssc:100152637)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Calcium-independent, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase that is involved in the regulation of cell differentiation in keratinocytes and pre-B cell receptor, mediates regulation of epithelial tight junction integrity and foam cell formation, and is required for glioblastoma proliferation and apoptosis prevention in MCF-7 cells. In keratinocytes, binds and activates the tyrosine kinase FYN, which in turn blocks epidermal growth factor receptor (EGFR) signaling and leads to keratinocyte growth arrest and differentiation. Associates with the cyclin CCNE1-CDK2-CDKN1B complex and inhibits CDK2 kinase activity, leading to RB1 dephosphorylation and thereby G1 arrest in keratinocytes. In association with RALA activates actin depolymerization, which is necessary for keratinocyte differentiation. In the pre-B cell receptor signaling, functions downstream of BLNK by up-regulating IRF4, which in turn activates L chain gene rearrangement. Regulates epithelial tight junctions (TJs) by phosphorylating occludin (OCLN) on threonine residues, which is necessary for the assembly and maintenance of TJs. In association with PLD2 and via TLR4 signaling, is involved in lipopolysaccharide (LPS)-induced RGS2 down-regulation and foam cell formation. Upon PMA stimulation, mediates glioblastoma cell proliferation by activating the mTOR pathway, the PI3K/AKT pathway and the ERK1-dependent phosphorylation of ELK1. Involved in the protection of glioblastoma cells from irradiation-induced apoptosis by preventing caspase-9 activation. In camptothecin-treated MCF-7 cells, regulates NF-kappa-B upstream signaling by activating IKBKB, and confers protection against DNA damage-induced apoptosis., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0008270 zinc ion binding;GO:0031267 small GTPase binding;GO:0004697 diacylglycerol-dependent serine/threonine kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0005911 cell-cell junction", "go_biological_process": "GO:0060252 positive regulation of glial cell proliferation;GO:0030154 cell differentiation;GO:0010744 positive regulation of macrophage derived foam cell differentiation;GO:0034351 negative regulation of glial cell apoptotic process;GO:0045618 positive regulation of keratinocyte differentiation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A5G2QQU6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1RRN0-1", "uniprot_id": "F1RRN0_PIG", "mass": 120666.0, "length": 1095, "protein_name": "Inactive tyrosine-protein kinase 7", "gene_name": "PTK7", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "PTK7", "gene_names_refseq": "", "protein_names_uniprotkb": "Inactive tyrosine-protein kinase 7; Protein-tyrosine kinase 7; Pseudo tyrosine kinase receptor 7; Tyrosine-protein kinase-like 7", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Inactive tyrosine kinase involved in Wnt signaling pathway. Component of both the non-canonical (also known as the Wnt/planar cell polarity signaling) and the canonical Wnt signaling pathway. Functions in cell adhesion, cell migration, cell polarity, proliferation, actin cytoskeleton reorganization and apoptosis. Has a role in embryogenesis, epithelial tissue organization and angiogenesis., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004672 protein kinase activity;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0008046 axon guidance receptor activity", "go_cellular_component": "GO:0016020 membrane;GO:0070161 anchoring junction;GO:0005886 plasma membrane;GO:0005911 cell-cell junction;GO:0030424 axon", "go_biological_process": "GO:0010976 positive regulation of neuron projection development;GO:0016477 cell migration;GO:0050808 synapse organization;GO:0071300 cellular response to retinoic acid;GO:0030036 actin cytoskeleton organization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1RRN0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A5G2QSB0-1", "uniprot_id": "A0A5G2QSB0_PIG", "mass": 102975.0, "length": 947, "protein_name": "Calcium-transporting ATPase", "gene_name": "ATP2C2", "organism": "Pig", "refseq_name": "calcium-transporting ATPase type 2C member 2", "refseq_ac": "XP_003126874", "gene_names_uniprotkb": "ATP2C2", "gene_names_refseq": "ATP2C2", "protein_names_uniprotkb": "Calcium-transporting ATPase; 7.2.2.10", "protein_names_refseq": "calcium-transporting ATPase type 2C member 2", "tax_id": 9823, "disease": "", "pathway": " (ssc:100514770); (R-SSC-936837)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "ATP-driven pump that supplies the Golgi apparatus with Ca(2+) and Mn(2+) ions, both essential cofactors for processing and trafficking of newly synthesized proteins in the secretory pathway. Within a catalytic cycle, acquires Ca(2+) or Mn(2+) ions on the cytoplasmic side of the membrane and delivers them to the lumenal side. The transfer of ions across the membrane is coupled to ATP hydrolysis and is associated with a transient phosphorylation that shifts the pump conformation from inward-facing to outward-facing state. Induces Ca(2+) influx independently of its ATP-driven pump function. At the basolateral membrane of mammary epithelial cells, interacts with Ca(2+) channel ORAI1 and mediates Ca(2+) entry independently of the Ca(2+) content of endoplasmic reticulum or Golgi stores. May facilitate transepithelial transport of large quantities of Ca(2+) for milk secretion via activation of Ca(2+) influx channels at the plasma membrane and active Ca(2+) transport at the Golgi apparatus., [UniProtKB, UniProtKB, UniProtKB]; Catalyzes the hydrolysis of ATP coupled with the transport of calcium., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0016887 ATP hydrolysis activity;GO:0005388 P-type calcium transporter activity;GO:0140613 P-type manganese transporter activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005783 endoplasmic reticulum;GO:0005886 plasma membrane;GO:0016323 basolateral plasma membrane;GO:0032588 trans-Golgi network membrane", "go_biological_process": "GO:0006874 intracellular calcium ion homeostasis;GO:0070588 calcium ion transmembrane transport;GO:0006828 manganese ion transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A5G2QSB0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A5G2QT35-1", "uniprot_id": "A0A5G2QT35_PIG", "mass": 56661.0, "length": 497, "protein_name": "Prostacyclin synthase", "gene_name": "PTGIS", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "PTGIS", "gene_names_refseq": "", "protein_names_uniprotkb": "Prostacyclin synthase; 4.2.1.152; 5.3.99.4; Hydroperoxy icosatetraenoate dehydratase; Prostaglandin I2 synthase", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-211979); (R-SSC-2162123)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Catalyzes the biosynthesis and metabolism of eicosanoids. Catalyzes the isomerization of prostaglandin H2 to prostacyclin (= prostaglandin I2), a potent mediator of vasodilation and inhibitor of platelet aggregation. Additionally, displays dehydratase activity, toward hydroperoxyeicosatetraenoates (HPETEs), especially toward (15S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate (15(S)-HPETE)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008116 prostaglandin-I synthase activity;GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0004497 monooxygenase activity;GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "go_cellular_component": "GO:0005634 nucleus;GO:0005788 endoplasmic reticulum lumen;GO:0005789 endoplasmic reticulum membrane;GO:0005901 caveola;GO:0005783 endoplasmic reticulum", "go_biological_process": "GO:0045766 positive regulation of angiogenesis;GO:0050728 negative regulation of inflammatory response;GO:0097190 apoptotic signaling pathway;GO:0071456 cellular response to hypoxia;GO:0045019 negative regulation of nitric oxide biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A5G2QT35-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A5G2QY96-1", "uniprot_id": "A0A5G2QY96_PIG", "mass": 50984.0, "length": 459, "protein_name": "Ribosomal RNA-processing protein 8", "gene_name": "RRP8", "organism": "Pig", "refseq_name": "ribosomal RNA-processing protein 8", "refseq_ac": "XP_003357182", "gene_names_uniprotkb": "RRP8", "gene_names_refseq": "RRP8", "protein_names_uniprotkb": "Ribosomal RNA-processing protein 8; 2.1.1.-", "protein_names_refseq": "ribosomal RNA-processing protein 8", "tax_id": 9823, "disease": "", "pathway": " (ssc:100623550); (R-SSC-427359)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Essential component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone-modifying enzymes. The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus. In the complex, RRP8 binds to H3K9me2 and probably acts as a methyltransferase., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008168 methyltransferase activity", "go_cellular_component": "GO:0005730 nucleolus;GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0005677 chromatin silencing complex;GO:0033553 rDNA heterochromatin", "go_biological_process": "GO:0006364 rRNA processing;GO:0032259 methylation;GO:0006351 DNA-templated transcription;GO:0045892 negative regulation of DNA-templated transcription;GO:0097009 energy homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A5G2QY96-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q28955-1", "uniprot_id": "NTAN1_PIG", "mass": 34890.0, "length": 311, "protein_name": "Protein N-terminal asparagine amidohydrolase", "gene_name": "NTAN1", "organism": "Pig", "refseq_name": "protein N-terminal asparagine amidohydrolase", "refseq_ac": "NP_999207", "gene_names_uniprotkb": "NTAN1", "gene_names_refseq": "NTAN1", "protein_names_uniprotkb": "Protein N-terminal asparagine amidohydrolase; 3.5.1.121; PNAA; PNAD; Protein N-terminal Asn amidase; Protein NH2-terminal asparagine amidohydrolase; Protein NH2-terminal asparagine deamidase; Protein NTN-amidase", "protein_names_refseq": "N-terminal asparagine amidohydrolase; PNAA; PNAD; protein N-terminal Asn amidase; protein N-terminal asparagine amidohydrolase; protein NH2-terminal asparagine amidohydrolase; protein NH2-terminal asparagine deamidase; protein NTN-amidase", "tax_id": 9823, "disease": "", "pathway": " (ssc:397107)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "32543654;7814382;8089117", "class_list": "", "function": "N-terminal asparagine deamidase that mediates deamidation of N-terminal asparagine residues to aspartate. Required for the ubiquitin-dependent turnover of intracellular proteins that initiate with Met-Asn. These proteins are acetylated on the retained initiator methionine and can subsequently be modified by the removal of N-acetyl methionine by acylaminoacid hydrolase (AAH). Conversion of the resulting N-terminal asparagine to aspartate by NTAN1/PNAD renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule. This enzyme does not act on substrates with internal or C-terminal asparagines and does not act on glutamine residues in any position., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A286ZPV6", "ec_number_list": "", "go_molecular_function": "GO:0008418 protein-N-terminal asparagine amidohydrolase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006511 ubiquitin-dependent protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q28955-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A9CQL8-1", "uniprot_id": "PXL2B_PIG", "mass": 21547.0, "length": 202, "protein_name": "Prostamide/prostaglandin F synthase", "gene_name": "PRXL2B", "organism": "Pig", "refseq_name": "prostamide/prostaglandin F synthase", "refseq_ac": "NP_001106912", "gene_names_uniprotkb": "PRXL2B; FAM213B", "gene_names_refseq": "FAM213B; PRXL2B", "protein_names_uniprotkb": "Prostamide/prostaglandin F synthase; 1.11.1.20; Peroxiredoxin-like 2B; Prostamide/PG F synthase; Prostamide/PGF synthase", "protein_names_refseq": "Prostamide/PGF synthase; family with sequence similarity 213 member B; prostamide/PG F synthase; prostamide/prostaglandin F synthase", "tax_id": 9823, "disease": "", "pathway": " (ssc:100134955)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "18006499;32543654", "class_list": "", "function": "Catalyzes the reduction of prostaglandin-ethanolamide H(2) (prostamide H(2)) to prostamide F(2alpha) with NADPH as proton donor. Also able to reduce prostaglandin H(2) to prostaglandin F(2alpha)., [UniProtKB, PubMed, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0036130 prostaglandin H2 endoperoxidase reductase activity;GO:0047017 prostaglandin F synthase activity;GO:0016491 oxidoreductase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005783 endoplasmic reticulum;GO:0005829 cytosol;GO:0043209 myelin sheath", "go_biological_process": "GO:0019371 cyclooxygenase pathway;GO:0001516 prostaglandin biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A9CQL8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A5G2QUJ6-1", "uniprot_id": "A0A5G2QUJ6_PIG", "mass": 35967.0, "length": 316, "protein_name": "Lys-63-specific deubiquitinase", "gene_name": "BRCC3", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "BRCC3", "gene_names_refseq": "", "protein_names_uniprotkb": "Lys-63-specific deubiquitinase; 3.4.19.-", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-5689901); (R-SSC-5693565); (R-SSC-5693571); (R-SSC-5693607); (R-SSC-69473)", "pathway_count": 5, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Metalloprotease that specifically cleaves 'Lys-63'-linked polyubiquitin chains. Component of the BRCA1-A complex, a complex that specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the brca1-bard1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). Catalytic subunit of the BRISC complex, a multiprotein complex that specifically cleaves 'Lys-63'-linked ubiquitin in various substrates. Mediates the specific 'Lys-63'-specific deubiquitination associated with the COP9 signalosome complex (CSN), via the interaction of the BRISC complex with the CSN complex. The BRISC complex is required for normal mitotic spindle assembly and microtubule attachment to kinetochores via its role in deubiquitinating NUMA1., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0031593 polyubiquitin modification-dependent protein binding;GO:0046872 metal ion binding;GO:0030234 enzyme regulator activity;GO:0004843 cysteine-type deubiquitinase activity;GO:0061578 K63-linked deubiquitinase activity", "go_cellular_component": "GO:0000922 spindle pole;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0070552 BRISC complex;GO:0070531 BRCA1-A complex", "go_biological_process": "GO:0006508 proteolysis;GO:0051301 cell division;GO:0070536 protein K63-linked deubiquitination;GO:0006302 double-strand break repair;GO:0045739 positive regulation of DNA repair", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A5G2QUJ6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A8W4FA46-1", "uniprot_id": "A0A8W4FA46_PIG", "mass": 218347.0, "length": 2100, "protein_name": "SH3 and multiple ankyrin repeat domains protein 1", "gene_name": "SHANK1", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "SHANK1", "gene_names_refseq": "", "protein_names_uniprotkb": "SH3 and multiple ankyrin repeat domains protein 1", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-6794361)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation., [UniProtKB, UniProtKB]", "predicted_glycosites": 12, "predicted_n_glycosites": 0, "predicted_o_glycosites": 12, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 12, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0035255 ionotropic glutamate receptor binding;GO:0098919 structural constituent of postsynaptic density;GO:0030160 synaptic receptor adaptor activity", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0005737 cytoplasm;GO:0014069 postsynaptic density;GO:0043197 dendritic spine;GO:0045211 postsynaptic membrane", "go_biological_process": "GO:0042048 olfactory behavior;GO:0046959 habituation;GO:0050894 determination of affect;GO:0008306 associative learning;GO:0030534 adult behavior", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A8W4FA46-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A8W4FF99-1", "uniprot_id": "A0A8W4FF99_PIG", "mass": 133868.0, "length": 1236, "protein_name": "Serine/threonine-protein kinase WNK4", "gene_name": "WNK4", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "WNK4", "gene_names_refseq": "", "protein_names_uniprotkb": "Serine/threonine-protein kinase WNK4; 2.7.11.1; Protein kinase lysine-deficient 4; Protein kinase with no lysine 4", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004672 protein kinase activity;GO:0005524 ATP binding;GO:0004674 protein serine/threonine kinase activity;GO:0019870 potassium channel inhibitor activity;GO:0031404 chloride ion binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005923 bicellular tight junction;GO:0044297 cell body;GO:0032991 protein-containing complex", "go_biological_process": "GO:0030644 intracellular chloride ion homeostasis;GO:0006954 inflammatory response;GO:0035556 intracellular signal transduction;GO:0008217 regulation of blood pressure;GO:0071466 cellular response to xenobiotic stimulus", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A8W4FF99-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A5GFT9-1", "uniprot_id": "A5GFT9_PIG", "mass": 111811.0, "length": 1045, "protein_name": "Guanine nucleotide-binding protein G(s) subunit alpha", "gene_name": "GNAS", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "GNAS", "gene_names_refseq": "", "protein_names_uniprotkb": "Guanine nucleotide-binding protein G(s) subunit alpha; Adenylate cyclase-stimulating G alpha protein", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Guanine nucleotide-binding proteins (G proteins) function as transducers in numerous signaling pathways controlled by G protein-coupled receptors (GPCRs)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0046872 metal ion binding;GO:0031683 G-protein beta/gamma-subunit complex binding;GO:0031698 beta-2 adrenergic receptor binding", "go_cellular_component": "GO:0005834 heterotrimeric G-protein complex;GO:0005737 cytoplasm;GO:0030425 dendrite", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway;GO:0071377 cellular response to glucagon stimulus;GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway;GO:0007606 sensory perception of chemical stimulus;GO:0120162 positive regulation of cold-induced thermogenesis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A5GFT9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SS88-1", "uniprot_id": "CFA52_PIG", "mass": 68118.0, "length": 620, "protein_name": "Cilia- and flagella-associated protein 52", "gene_name": "CFAP52", "organism": "Pig", "refseq_name": "cilia- and flagella-associated protein 52", "refseq_ac": "XP_020921925", "gene_names_uniprotkb": "CFAP52; WDR16", "gene_names_refseq": "CFAP52; WDR16", "protein_names_uniprotkb": "Cilia- and flagella-associated protein 52; WD repeat-containing protein 16", "protein_names_refseq": "WD repeat domain 16; WD repeat-containing protein 16; cilia- and flagella-associated protein 52", "tax_id": 9823, "disease": "", "pathway": " (ssc:100516337)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "30723633;32543654;33139725", "class_list": "", "function": "Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme (By similarity). Important for proper ciliary and flagellar beating. May act in cooperation with CFAP45 and axonemal dynein subunit DNAH11 (PubMed:33139725). May play a role in cell growth and/or survival (By similarity)., [UniProtKB, PubMed, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0036126 sperm flagellum;GO:0005930 axoneme;GO:0005879 axonemal microtubule;GO:0097225 sperm midpiece;GO:0097729 9+2 motile cilium", "go_biological_process": "GO:0030317 flagellated sperm motility;GO:0061966 establishment of left/right asymmetry", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "F1SS88-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A5G2QZD9-1", "uniprot_id": "A0A5G2QZD9_PIG", "mass": 68583.0, "length": 614, "protein_name": "Cryptochrome-2", "gene_name": "CRY2", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "CRY2", "gene_names_refseq": "", "protein_names_uniprotkb": "Cryptochrome-2", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0019901 protein kinase binding;GO:0071949 FAD binding;GO:0003684 damaged DNA binding;GO:0000976 transcription cis-regulatory region binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005829 cytosol", "go_biological_process": "GO:2000850 negative regulation of glucocorticoid secretion;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0045892 negative regulation of DNA-templated transcription;GO:0042593 glucose homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A5G2QZD9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A5G2QZL7-1", "uniprot_id": "A0A5G2QZL7_PIG", "mass": 162726.0, "length": 1451, "protein_name": "protein-tyrosine-phosphatase", "gene_name": "PTPRT", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "PTPRT", "gene_names_refseq": "", "protein_names_uniprotkb": "protein-tyrosine-phosphatase; 3.1.3.48", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0097677 STAT family protein binding;GO:0042803 protein homodimerization activity;GO:0051393 alpha-actinin binding;GO:0045296 cadherin binding;GO:0008013 beta-catenin binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0009986 cell surface", "go_biological_process": "GO:0007165 signal transduction;GO:0007169 cell surface receptor protein tyrosine kinase signaling pathway;GO:0031175 neuron projection development;GO:0030336 negative regulation of cell migration;GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A5G2QZL7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A5G2QZY6-1", "uniprot_id": "A0A5G2QZY6_PIG", "mass": 25039.0, "length": 221, "protein_name": "GTP-binding nuclear protein Ran", "gene_name": "RAN", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "RAN", "gene_names_refseq": "", "protein_names_uniprotkb": "GTP-binding nuclear protein Ran", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (ssc:397655)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006913 nucleocytoplasmic transport;GO:0015031 protein transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A5G2QZY6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A5G2R0G8-1", "uniprot_id": "A0A5G2R0G8_PIG", "mass": 108428.0, "length": 944, "protein_name": "Aminopeptidase", "gene_name": "ENPEP", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "ENPEP", "gene_names_refseq": "", "protein_names_uniprotkb": "Aminopeptidase; 3.4.11.-", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-2022377)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Regulates central hypertension through its calcium-modulated preference to cleave N-terminal acidic residues from peptides such as angiotensin II., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0070006 metalloaminopeptidase activity;GO:0004230 glutamyl aminopeptidase activity;GO:0008237 metallopeptidase activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005886 plasma membrane;GO:0005903 brush border;GO:0009897 external side of plasma membrane;GO:0016324 apical plasma membrane", "go_biological_process": "GO:0002003 angiotensin maturation;GO:0043171 peptide catabolic process;GO:0032835 glomerulus development;GO:0006508 proteolysis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A5G2R0G8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1RMJ0-1", "uniprot_id": "F1RMJ0_PIG", "mass": 93386.0, "length": 822, "protein_name": "Tyrosine-protein kinase", "gene_name": "FES", "organism": "Pig", "refseq_name": "tyrosine-protein kinase Fes/Fps isoform X2", "refseq_ac": "XP_001929390", "gene_names_uniprotkb": "FES", "gene_names_refseq": "FES", "protein_names_uniprotkb": "Tyrosine-protein kinase; 2.7.10.2", "protein_names_refseq": "tyrosine-protein kinase Fes/Fps isoform X2", "tax_id": 9823, "disease": "", "pathway": " (ssc:100155631); (R-SSC-1433557); (R-SSC-399954); (R-SSC-399956)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Tyrosine-protein kinase that acts downstream of cell surface receptors and plays a role in the regulation of the actin cytoskeleton, microtubule assembly, cell attachment and cell spreading. Plays a role in FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Acts down-stream of the activated FCER1 receptor and the mast/stem cell growth factor receptor KIT. Plays a role in the regulation of mast cell degranulation. Plays a role in the regulation of cell differentiation and promotes neurite outgrowth in response to NGF signaling. Plays a role in cell scattering and cell migration in response to HGF-induced activation of EZR. Phosphorylates BCR and down-regulates BCR kinase activity. Phosphorylates HCLS1/HS1, PECAM1, STAT3 and TRIM28., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004715 non-membrane spanning protein tyrosine kinase activity;GO:0005524 ATP binding;GO:0034987 immunoglobulin receptor binding;GO:0004713 protein tyrosine kinase activity;GO:0008017 microtubule binding", "go_cellular_component": "GO:0005856 cytoskeleton;GO:0005829 cytosol;GO:0015630 microtubule cytoskeleton;GO:0005886 plasma membrane;GO:0005925 focal adhesion", "go_biological_process": "GO:0006935 chemotaxis;GO:0007155 cell adhesion;GO:0010976 positive regulation of neuron projection development;GO:0030155 regulation of cell adhesion;GO:0042127 regulation of cell population proliferation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1RMJ0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A5G2R2I1-1", "uniprot_id": "A0A5G2R2I1_PIG", "mass": 92857.0, "length": 837, "protein_name": "Plakophilin-2", "gene_name": "PKP2", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "PKP2", "gene_names_refseq": "", "protein_names_uniprotkb": "Plakophilin-2", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-6805567); (R-SSC-6809371)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0060090 molecular adaptor activity;GO:0003677 DNA binding;GO:0005080 protein kinase C binding;GO:0045296 cadherin binding;GO:0045294 alpha-catenin binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0005912 adherens junction", "go_biological_process": "GO:1900024 regulation of substrate adhesion-dependent cell spreading;GO:0045110 intermediate filament bundle assembly;GO:0048496 maintenance of animal organ identity;GO:0007267 cell-cell signaling;GO:0007507 heart development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A5G2R2I1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A8D1DGF2-1", "uniprot_id": "A0A8D1DGF2_PIG", "mass": 79982.0, "length": 718, "protein_name": "Polyunsaturated fatty acid lipoxygenase ALOX15", "gene_name": "ALOX15B", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "ALOX15B", "gene_names_refseq": "", "protein_names_uniprotkb": "Polyunsaturated fatty acid lipoxygenase ALOX15; 1.13.11.12; 12/15-lipoxygenase; Arachidonate 12-lipoxygenase, leukocyte-type; Arachidonate 15-lipoxygenase; Arachidonate omega-6 lipoxygenase; Erythroid cell-specific 15-lipoxygenase; Hepoxilin A3 synthase Alox15; Linoleate 13S-lipoxygenase", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-2142770)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "F1SSZ0", "ec_number_list": "", "go_molecular_function": "GO:0005506 iron ion binding;GO:0004052 arachidonate 12(S)-lipoxygenase activity;GO:0005509 calcium ion binding;GO:0008289 lipid binding;GO:0016165 linoleate 13S-lipoxygenase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005811 lipid droplet;GO:0005829 cytosol;GO:0005856 cytoskeleton;GO:0005886 plasma membrane", "go_biological_process": "GO:0034440 lipid oxidation;GO:0019369 arachidonate metabolic process;GO:0071926 endocannabinoid signaling pathway;GO:0008285 negative regulation of cell population proliferation;GO:0032722 positive regulation of chemokine production", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A8D1DGF2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A5G2RMY7-1", "uniprot_id": "A0A5G2RMY7_PIG", "mass": 95642.0, "length": 858, "protein_name": "Endothelin-converting enzyme 1", "gene_name": "ECE1", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "ECE1", "gene_names_refseq": "", "protein_names_uniprotkb": "Endothelin-converting enzyme 1; 3.4.24.71", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-375276)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Converts big endothelin-1 to endothelin-1., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004222 metalloendopeptidase activity;GO:0008270 zinc ion binding;GO:0042803 protein homodimerization activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005768 endosome;GO:0005886 plasma membrane;GO:0048471 perinuclear region of cytoplasm;GO:0009897 external side of plasma membrane;GO:0033093 Weibel-Palade body", "go_biological_process": "GO:0016486 peptide hormone processing;GO:0071526 semaphorin-plexin signaling pathway;GO:0001921 positive regulation of receptor recycling;GO:0042733 embryonic digit morphogenesis;GO:0043583 ear development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A5G2RMY7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A5K1TV72-1", "uniprot_id": "A0A5K1TV72_PIG", "mass": 176871.0, "length": 1597, "protein_name": "ADAM metallopeptidase with thrombospondin type 1 motif 12", "gene_name": "ADAMTS12", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "ADAMTS12", "gene_names_refseq": "", "protein_names_uniprotkb": "ADAM metallopeptidase with thrombospondin type 1 motif 12", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-5173214)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004222 metalloendopeptidase activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0031012 extracellular matrix", "go_biological_process": "GO:0043931 ossification involved in bone maturation;GO:0016477 cell migration;GO:0007160 cell-matrix adhesion;GO:0030199 collagen fibril organization;GO:0050727 regulation of inflammatory response", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A5K1TV72-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A900P2M2-1", "uniprot_id": "A0A900P2M2_PIG", "mass": 43387.0, "length": 386, "protein_name": "Growth hormone secretagogue receptor type 1", "gene_name": "GHSR", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "GHSR", "gene_names_refseq": "", "protein_names_uniprotkb": "Growth hormone secretagogue receptor type 1; GH-releasing peptide receptor; Ghrelin receptor", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-416476)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Cytokine that binds to TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and possibly also to TNFRSF11B/OPG. Induces apoptosis. Its activity may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and TNFRSF11B/OPG that cannot induce apoptosis., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0046872 metal ion binding;GO:0005125 cytokine activity;GO:0005164 tumor necrosis factor receptor binding;GO:0004930 G protein-coupled receptor activity;GO:0001616 growth hormone secretagogue receptor activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005886 plasma membrane;GO:0009986 cell surface;GO:0045121 membrane raft;GO:0043005 neuron projection", "go_biological_process": "GO:0006955 immune response;GO:0006915 apoptotic process;GO:2001238 positive regulation of extrinsic apoptotic signaling pathway;GO:0032100 positive regulation of appetite;GO:0007186 G protein-coupled receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A900P2M2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A5K1V5Y3-1", "uniprot_id": "A0A5K1V5Y3_PIG", "mass": 62821.0, "length": 583, "protein_name": "SHC-transforming protein 1", "gene_name": "SHC1", "organism": "Pig", "refseq_name": "SHC-transforming protein 1 isoform X2", "refseq_ac": "XP_001929432", "gene_names_uniprotkb": "SHC1", "gene_names_refseq": "SHC1", "protein_names_uniprotkb": "SHC-transforming protein 1; Src homology 2 domain-containing-transforming protein C1", "protein_names_refseq": "SHC-transforming protein 1 isoform X2", "tax_id": 9823, "disease": "", "pathway": " (ssc:100156321); (R-SSC-1250196); (R-SSC-1250347); (R-SSC-167044); (R-SSC-180336); (R-SSC-201556); (R-SSC-210993); (R-SSC-2424491); (R-SSC-2428933); (R-SSC-2730905); (R-SSC-2871796); (R-SSC-2871809); (R-SSC-354192); (R-SSC-512988); (R-SSC-5654688); (R-SSC-5654699); (R-SSC-5654704); (R-SSC-5654719); (R-SSC-5673001); (R-SSC-74749); (R-SSC-74751); (R-SSC-8851805); (R-SSC-8853659); (R-SSC-8983432); (R-SSC-9009391); (R-SSC-9020558); (R-SSC-9027284); (R-SSC-912526); (R-SSC-9634597); (R-SSC-9674555)", "pathway_count": 30, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0001784 phosphotyrosine residue binding;GO:0005158 insulin receptor binding;GO:0046875 ephrin receptor binding;GO:0005159 insulin-like growth factor receptor binding;GO:0005168 neurotrophin TRKA receptor binding", "go_cellular_component": "GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0005737 cytoplasm", "go_biological_process": "GO:0035556 intracellular signal transduction;GO:0043066 negative regulation of apoptotic process;GO:0043410 positive regulation of MAPK cascade;GO:0045892 negative regulation of DNA-templated transcription;GO:0045893 positive regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A5K1V5Y3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A5GFN6-1", "uniprot_id": "RAEL1_PIG", "mass": 41025.0, "length": 368, "protein_name": "mRNA export factor", "gene_name": "RAE1", "organism": "Pig", "refseq_name": "mRNA export factor", "refseq_ac": "NP_001098766", "gene_names_uniprotkb": "RAE1; MRNP41", "gene_names_refseq": "MRNP41; RAE1", "protein_names_uniprotkb": "mRNA export factor; Rae1 protein homolog; mRNA-associated protein mrnp 41", "protein_names_refseq": "RAE1 RNA export 1 homolog; mRNA export factor; mRNA-associated protein mrnp 41; rae1 protein homolog", "tax_id": 9823, "disease": "", "pathway": " (ssc:100125839); (R-SSC-159227); (R-SSC-159230); (R-SSC-159231); (R-SSC-159236); (R-SSC-1855170); (R-SSC-1855196); (R-SSC-1855229); (R-SSC-191859); (R-SSC-3108214); (R-SSC-3232142); (R-SSC-3301854); (R-SSC-3371453); (R-SSC-4085377); (R-SSC-4551638); (R-SSC-4570464); (R-SSC-4615885)", "pathway_count": 17, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Plays a role in mitotic bipolar spindle formation. Binds mRNA. May function in nucleocytoplasmic transport and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding;GO:0043130 ubiquitin binding", "go_cellular_component": "GO:0005643 nuclear pore;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0001650 fibrillar center;GO:0097431 mitotic spindle pole", "go_biological_process": "GO:0051301 cell division;GO:0060236 regulation of mitotic spindle organization;GO:0006405 RNA export from nucleus;GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A5GFN6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "B3SP85-1", "uniprot_id": "GILT_PIG", "mass": 27614.0, "length": 246, "protein_name": "Gamma-interferon-inducible-lysosomal thiol reductase", "gene_name": "IFI30", "organism": "Pig", "refseq_name": "gamma-interferon-inducible-lysosomal thiol reductase precursor", "refseq_ac": "NP_001124518", "gene_names_uniprotkb": "IFI30; GILT", "gene_names_refseq": "GILT; IFI30", "protein_names_uniprotkb": "Gamma-interferon-inducible-lysosomal thiol reductase; 1.8.4.-", "protein_names_refseq": "gamma-inducible interferon 30; gamma-interferon-inducible-lysosomal thiol reductase precursor; gamma-interferon-inducible-lysosomal thiol reductase; interferon, gamma-inducible protein 30", "tax_id": 9823, "disease": "", "pathway": " (ssc:100174943)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "18722674;32543654", "class_list": "", "function": "Lysosomal thiol reductase that can reduce protein disulfide bonds. Facilitates the complete unfolding of proteins destined for lysosomal degradation. Plays an important role in antigen processing., [UniProtKB, UniProtKB]; Lysosomal thiol reductase that catalyzes protein disulfide bonds reduction. Plays an important role in antigen processing and presentation, of namely both major histocompatibility complex (MHC) class I- and class II-restricted antigen by reducing the disulfide bonds of endocytosed proteins and facilitating their unfolding and optimal degradation. Shares with thioredoxin a reduction mechanism in which the N-terminal cysteine thiol group in the CXXC active site motif initiates a nucleophilic attack on the substrate disulfide bond,resulting in the formation of a mixed disulfide-linked enzyme-substrate intermediate. Subsequent intramolecular attack by the second cysteine thiol group enables the release of the reduced substrate and oxidized enzyme. Lysosomal cysteine is a physiological reducing agent that is capable of reducing IFI30, so that it can catalyzes the next reaction. Dithiothreitol, cysteine, and cysteinyl glycine, but not glutathione, are capable of regenerating active precursor and mature IFI30 in vitro., [UniProtKB, UniProtKB]; The cloning and characterization of porcine gamma-interferon-inducible lysosomal thiol reductase (GILT) are reported., [RefSeq, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor", "go_cellular_component": "GO:0005576 extracellular region;GO:0005764 lysosome", "go_biological_process": "GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "B3SP85-1", "record_type": "protein" }, { "uniprot_canonical_ac": "B5KFD7-1", "uniprot_id": "GRB10_PIG", "mass": 66386.0, "length": 589, "protein_name": "Growth factor receptor-bound protein 10", "gene_name": "GRB10; Grb10", "organism": "Pig", "refseq_name": "growth factor receptor-bound protein 10", "refseq_ac": "NP_001128437", "gene_names_uniprotkb": "GRB10; Grb10", "gene_names_refseq": "GRB10", "protein_names_uniprotkb": "Growth factor receptor-bound protein 10; GRB10 adapter protein", "protein_names_refseq": "GRB10 adapter protein; growth factor receptor-bound protein 10", "tax_id": 9823, "disease": "", "pathway": " (ssc:100188977); (R-SSC-1433557); (R-SSC-74713); (R-SSC-74749); (R-SSC-74751); (R-SSC-8853659); (R-SSC-9607240)", "pathway_count": 7, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Adapter protein which modulates coupling of a number of cell surface receptor kinases with specific signaling pathways. Binds to, and suppress signals from, activated receptors tyrosine kinases, including the insulin (INSR) and insulin-like growth factor (IGF1R) receptors. The inhibitory effect can be achieved by 2 mechanisms: interference with the signaling pathway and increased receptor degradation. Delays and reduces AKT1 phosphorylation in response to insulin stimulation. Blocks association between INSR and IRS1 and IRS2 and prevents insulin-stimulated IRS1 and IRS2 tyrosine phosphorylation. Recruits NEDD4 to IGF1R, leading to IGF1R ubiquitination, increased internalization and degradation by both the proteasomal and lysosomal pathways. A similar role in the mediation of ubiquitination also has been suggested with INSR. Negatively regulates Wnt signaling by interacting with LRP6 intracellular portion and interfering with the binding of AXIN1 to LRP6. Positive regulator of the KDR/VEGFR-2 signaling pathway. May inhibit NEDD4-mediated degradation of KDR/VEGFR-2 (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "B5KFD3;B5KFD4;B5KFD6", "ec_number_list": "", "go_molecular_function": "GO:0005158 insulin receptor binding;GO:0030159 signaling receptor complex adaptor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0032991 protein-containing complex", "go_biological_process": "GO:0046627 negative regulation of insulin receptor signaling pathway;GO:0035556 intracellular signal transduction;GO:0008286 insulin receptor signaling pathway;GO:0030178 negative regulation of Wnt signaling pathway;GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "B5KFD7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A1E295-1", "uniprot_id": "CATB_PIG", "mass": 36901.0, "length": 335, "protein_name": "Cathepsin B", "gene_name": "CTSB", "organism": "Pig", "refseq_name": "cathepsin B precursor", "refseq_ac": "NP_001090927", "gene_names_uniprotkb": "CTSB", "gene_names_refseq": "CTSB", "protein_names_uniprotkb": "Cathepsin B; 3.4.22.1", "protein_names_refseq": "cathepsin B precursor", "tax_id": 9823, "disease": "", "pathway": " (ssc:100037961); (R-SSC-1442490); (R-SSC-1679131); (R-SSC-2132295); (R-SSC-6798695)", "pathway_count": 5, "publication_count": 4, "publication_id_list": "20107207;22261194;24878992;32543654", "class_list": "", "function": "CTSB may be required to remodel endometrial and placental tissues for close apposition between maternal and fetal vasculatures and to facilitate transplacental transport of gases, micronutrients (amino acids, glucose), and macromolecules (proteins)., [RefSeq, PubMed]; Findings showed that CTSB facilitates adipogenesis, and its effect is associated with fibronectin degradation and Wnt/b-catenin signaling pathway., [RefSeq, PubMed]; Thiol protease which is believed to participate in intracellular degradation and turnover of proteins (By similarity). Cleaves matrix extracellular phosphoglycoprotein MEPE (By similarity). Involved in the solubilization of cross-linked TG/thyroglobulin in the thyroid follicle lumen (By similarity). Has also been implicated in tumor invasion and metastasis (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004175 endopeptidase activity;GO:0004197 cysteine-type endopeptidase activity;GO:0005518 collagen binding;GO:0043394 proteoglycan binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005764 lysosome;GO:0016324 apical plasma membrane;GO:0042470 melanosome;GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "GO:0051603 proteolysis involved in protein catabolic process;GO:0030855 epithelial cell differentiation;GO:0046718 symbiont entry into host cell;GO:0030574 collagen catabolic process;GO:0097067 cellular response to thyroid hormone stimulus", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A1E295-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A1E952-1", "uniprot_id": "MSRB1_PIG", "mass": 12783.0, "length": 116, "protein_name": "Methionine-R-sulfoxide reductase B1", "gene_name": "MSRB1", "organism": "Pig", "refseq_name": "methionine-R-sulfoxide reductase B1", "refseq_ac": "NP_001090929", "gene_names_uniprotkb": "MSRB1; SEPX1", "gene_names_refseq": "MSRB1; SEPX1", "protein_names_uniprotkb": "Methionine-R-sulfoxide reductase B1; 1.8.4.12; 1.8.4.14; MsrB1; SelX; Selenoprotein X", "protein_names_refseq": "methionine-R-sulfoxide reductase B1; selX; selenoprotein X, 1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100037965)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases, methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residue. Acts as a regulator of actin assembly by reducing methionine (R)-sulfoxide mediated by MICALs (MICAL1, MICAL2 or MICAL3) on actin, thereby promoting filament repolymerization. Plays a role in innate immunity by reducing oxidized actin, leading to actin repolymerization in macrophages., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0033743 peptide-methionine (R)-S-oxide reductase activity;GO:0033745 L-methionine-(R)-S-oxide reductase activity;GO:0003779 actin binding;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0015629 actin cytoskeleton", "go_biological_process": "GO:0045087 innate immune response;GO:0030041 actin filament polymerization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A1E952-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P23687-1", "uniprot_id": "PPCE_PIG", "mass": 80770.0, "length": 710, "protein_name": "Prolyl endopeptidase", "gene_name": "PREP", "organism": "Pig", "refseq_name": "prolyl endopeptidase", "refseq_ac": "NP_001004050", "gene_names_uniprotkb": "PREP", "gene_names_refseq": "PREP", "protein_names_uniprotkb": "Prolyl endopeptidase; 3.4.21.26; PE; Post-proline cleaving enzyme", "protein_names_refseq": "PE; post-proline cleaving enzyme; prolyl endopeptidase", "tax_id": 9823, "disease": "", "pathway": " (ssc:445540)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "1900195;2064618;22132071;27434808;32543654;9695945", "class_list": "", "function": "Cleaves peptide bonds on the C-terminal side of prolyl residues within peptides that are up to approximately 30 amino acids long., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Ion mobility mass spectrometry (IMMS) experiments detected two species of PREP that correlated well with the open and closed conformations in dynamic equilibrium. Therefore, these findings emphasize the value of IMMS for the study of multiple co-existing conformations of large proteins in slow equilibrium in solution., [RefSeq, PubMed]; Molecular modeling and docking based approaches were used to unravel questions like differences in ligand binding affinities in three POP species (porcine, human and A. thaliana)., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004252 serine-type endopeptidase activity;GO:0004181 metallocarboxypeptidase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005576 extracellular region;GO:0005634 nucleus;GO:0005829 cytosol", "go_biological_process": "GO:0006508 proteolysis;GO:0002003 angiotensin maturation", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P23687-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A5S6HX62-1", "uniprot_id": "A0A5S6HX62_PIG", "mass": 27988.0, "length": 249, "protein_name": "Myogenin", "gene_name": "MYOG", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "MYOG", "gene_names_refseq": "", "protein_names_uniprotkb": "Myogenin", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-525793)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0046983 protein dimerization activity;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0031490 chromatin DNA binding;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005654 nucleoplasm", "go_biological_process": "GO:0010831 positive regulation of myotube differentiation;GO:0014891 striated muscle atrophy;GO:0006351 DNA-templated transcription;GO:0008285 negative regulation of cell population proliferation;GO:0045944 positive regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A5S6HX62-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A8D0R082-1", "uniprot_id": "A0A8D0R082_PIG", "mass": 45178.0, "length": 406, "protein_name": "Sodium-coupled neutral amino acid symporter 2", "gene_name": "SLC38A2", "organism": "Pig", "refseq_name": "sodium-coupled neutral amino acid transporter 2 isoform X2", "refseq_ac": "XP_013853418", "gene_names_uniprotkb": "SLC38A2", "gene_names_refseq": "SLC38A2; SNAT2", "protein_names_uniprotkb": "Sodium-coupled neutral amino acid symporter 2; Amino acid transporter A2; Solute carrier family 38 member 2; System A amino acid transporter 2; System A transporter 1; System N amino acid transporter 2", "protein_names_refseq": "sodium-coupled neutral amino acid transporter 2 isoform X2", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-210500); (R-SSC-352230)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Symporter that cotransports neutral amino acids and sodium ions from the extracellular to the intracellular side of the cell membrane. The transport is pH-sensitive, Li(+)-intolerant, electrogenic, driven by the Na(+) electrochemical gradient and cotransports of neutral amino acids and sodium ions with a stoichiometry of 1:1. May function in the transport of amino acids at the blood-brain barrier. May function in the transport of amino acids in the supply of maternal nutrients to the fetus through the placenta. Maintains a key metabolic glutamine/glutamate balance underpinning retrograde signaling by dendritic release of the neurotransmitter glutamate. Transports L-proline in differentiating osteoblasts for the efficient synthesis of proline-enriched proteins and provides proline essential for osteoblast differentiation and bone formation during bone development., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A288CFU8", "ec_number_list": "", "go_molecular_function": "GO:0015186 L-glutamine transmembrane transporter activity;GO:0005295 neutral L-amino acid:sodium symporter activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane", "go_biological_process": "GO:0033120 positive regulation of RNA splicing;GO:0015824 proline transport;GO:0006868 glutamine transport;GO:0003333 amino acid transmembrane transport;GO:0080135 regulation of cellular response to stress", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A8D0R082-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A8D0XQ50-1", "uniprot_id": "A0A8D0XQ50_PIG", "mass": 58509.0, "length": 514, "protein_name": "E3 ubiquitin-protein ligase XIAP", "gene_name": "XIAP", "organism": "Pig", "refseq_name": "E3 ubiquitin-protein ligase XIAP isoform X1", "refseq_ac": "XP_020935024", "gene_names_uniprotkb": "XIAP", "gene_names_refseq": "BIRC4; XIAP", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase XIAP; 2.3.2.27; Baculoviral IAP repeat-containing protein 4; Inhibitor of apoptosis protein 3; RING-type E3 ubiquitin transferase XIAP; X-linked inhibitor of apoptosis protein", "protein_names_refseq": "E3 ubiquitin-protein ligase XIAP isoform X1", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-111459); (R-SSC-111463); (R-SSC-111464); (R-SSC-111469); (R-SSC-3769402); (R-SSC-5357786); (R-SSC-5357905); (R-SSC-5357956); (R-SSC-5675482); (R-SSC-8948747); (R-SSC-8948751); (R-SSC-9627069); (R-SSC-9958825)", "pathway_count": 13, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A287A6L6", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0042802 identical protein binding;GO:0061630 ubiquitin protein ligase activity;GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process;GO:0004869 cysteine-type endopeptidase inhibitor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway;GO:0070431 nucleotide-binding oligomerization domain containing 2 signaling pathway;GO:0060785 regulation of apoptosis involved in tissue homeostasis;GO:0032496 response to lipopolysaccharide;GO:0043066 negative regulation of apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A8D0XQ50-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1RRA8-1", "uniprot_id": "F1RRA8_PIG", "mass": 110640.0, "length": 984, "protein_name": "Serine/threonine-protein kinase PLK4", "gene_name": "PLK4", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "PLK4", "gene_names_refseq": "", "protein_names_uniprotkb": "Serine/threonine-protein kinase PLK4; 2.7.11.21; Polo-like kinase 4; Serine/threonine-protein kinase SAK", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-2565942); (R-SSC-380259); (R-SSC-380270); (R-SSC-380284); (R-SSC-380320); (R-SSC-5620912); (R-SSC-8854518)", "pathway_count": 7, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0042802 identical protein binding", "go_cellular_component": "GO:0032154 cleavage furrow;GO:0005814 centriole;GO:0005634 nucleus;GO:0005730 nucleolus;GO:0005813 centrosome", "go_biological_process": "GO:0007099 centriole replication;GO:0060271 cilium assembly;GO:0060707 trophoblast giant cell differentiation;GO:0098535 de novo centriole assembly involved in multi-ciliated epithelial cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1RRA8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A8D1AA90-1", "uniprot_id": "A0A8D1AA90_PIG", "mass": 73967.0, "length": 658, "protein_name": "Carnitine O-palmitoyltransferase 2, mitochondrial", "gene_name": "CPT2", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "CPT2", "gene_names_refseq": "", "protein_names_uniprotkb": "Carnitine O-palmitoyltransferase 2, mitochondrial; 2.3.1.21; Carnitine palmitoyltransferase II", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-200425); (R-SSC-77305)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Involved in the intramitochondrial synthesis of acylcarnitines from accumulated acyl-CoA metabolites. Reconverts acylcarnitines back into the respective acyl-CoA esters that can then undergo beta-oxidation, an essential step for the mitochondrial uptake of long-chain fatty acids and their subsequent beta-oxidation in the mitochondrion. Active with medium (C8-C12) and long-chain (C14-C18) acyl-CoA esters., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A5G2R8A9", "ec_number_list": "", "go_molecular_function": "GO:0004095 carnitine O-palmitoyltransferase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane;GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0001676 long-chain fatty acid metabolic process;GO:0006635 fatty acid beta-oxidation;GO:0006853 carnitine shuttle;GO:0009437 carnitine metabolic process;GO:0120162 positive regulation of cold-induced thermogenesis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A8D1AA90-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P29269-1", "uniprot_id": "MYL9_PIG", "mass": 19827.0, "length": 172, "protein_name": "Myosin regulatory light polypeptide 9", "gene_name": "MYL9", "organism": "Pig", "refseq_name": "myosin regulatory light polypeptide 9", "refseq_ac": "NP_001231401", "gene_names_uniprotkb": "MYL9; MYRL2", "gene_names_refseq": "LC20; MYL9; MYRL2", "protein_names_uniprotkb": "Myosin regulatory light polypeptide 9; 20 kDa myosin light chain; LC20; Myosin regulatory light chain 2, smooth muscle isoform; Myosin regulatory light chain 9", "protein_names_refseq": "20 kDa myosin light chain; myosin regulatory light chain 9; myosin regulatory light polypeptide 9", "tax_id": 9823, "disease": "", "pathway": " (ssc:100157760); (R-SSC-445355); (R-SSC-5627123)", "pathway_count": 3, "publication_count": 2, "publication_id_list": "1490997;32543654", "class_list": "", "function": "Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Implicated in cytokinesis, receptor capping, and cell locomotion (By similarity). In myoblasts, may regulate PIEZO1-dependent cortical actomyosin assembly involved in myotube formation (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005509 calcium ion binding;GO:0032036 myosin heavy chain binding;GO:0005200 structural constituent of cytoskeleton", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005938 cell cortex;GO:0001725 stress fiber;GO:0030016 myofibril;GO:0016460 myosin II complex", "go_biological_process": "GO:0030239 myofibril assembly;GO:0043149 stress fiber assembly", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "P29269-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A8D1NBV7-1", "uniprot_id": "A0A8D1NBV7_PIG", "mass": 44982.0, "length": 405, "protein_name": "5-hydroxytryptamine receptor 1B", "gene_name": "HTR1B", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "HTR1B", "gene_names_refseq": "", "protein_names_uniprotkb": "5-hydroxytryptamine receptor 1B; 5-HT-1B; 5-HT1B; Serotonin receptor 1B", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-390666); (R-SSC-418594)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for ergot alkaloid derivatives, various anxiolytic and antidepressant drugs and other psychoactive substances, such as lysergic acid diethylamide (LSD). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors, such as adenylate cyclase. HTR1B is coupled to G(i)/G(o) G alpha proteins and mediates inhibitory neurotransmission by inhibiting adenylate cyclase activity. Arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Regulates the release of 5-hydroxytryptamine, dopamine and acetylcholine in the brain, and thereby affects neural activity, nociceptive processing, pain perception, mood and behavior. Besides, plays a role in vasoconstriction of cerebral arteries., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A5G2QFS0", "ec_number_list": "", "go_molecular_function": "GO:0004993 G protein-coupled serotonin receptor activity;GO:0030594 neurotransmitter receptor activity;GO:0051378 serotonin binding;GO:0001586 Gi/o-coupled serotonin receptor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0030425 dendrite;GO:0042734 presynaptic membrane;GO:0099154 serotonergic synapse", "go_biological_process": "GO:0007187 G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007268 chemical synaptic transmission;GO:0071466 cellular response to xenobiotic stimulus;GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway;GO:0014063 negative regulation of serotonin secretion", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A8D1NBV7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A8D1NTU1-1", "uniprot_id": "A0A8D1NTU1_PIG", "mass": 35642.0, "length": 313, "protein_name": "Serine/threonine-protein kinase", "gene_name": "PIM1", "organism": "Pig", "refseq_name": "serine/threonine-protein kinase pim-1", "refseq_ac": "XP_005665984", "gene_names_uniprotkb": "PIM1", "gene_names_refseq": "PIM1", "protein_names_uniprotkb": "Serine/threonine-protein kinase; 2.7.11.1", "protein_names_refseq": "serine/threonine-protein kinase pim-1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100157844); (R-SSC-9968551)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "F1RVS6", "ec_number_list": "", "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0030145 manganese ion binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:1904263 positive regulation of TORC1 signaling;GO:0070561 vitamin D receptor signaling pathway;GO:1905062 positive regulation of cardioblast proliferation;GO:0043066 negative regulation of apoptotic process;GO:0006915 apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A8D1NTU1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "C5HGF3-1", "uniprot_id": "TMCO1_PIG", "mass": 21175.0, "length": 188, "protein_name": "Calcium load-activated calcium channel", "gene_name": "TMCO1", "organism": "Pig", "refseq_name": "calcium load-activated calcium channel", "refseq_ac": "NP_001161057", "gene_names_uniprotkb": "TMCO1", "gene_names_refseq": "TMCO1", "protein_names_uniprotkb": "Calcium load-activated calcium channel; CLAC channel; GEL complex subunit TMCO1; Transmembrane and coiled-coil domain-containing protein 1", "protein_names_refseq": "CLAC channel; GEL complex subunit TMCO1; Transmembrane and coiled-coil domains protein 1; calcium load-activated calcium channel; transmembrane and coiled-coil domain-containing protein 1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100151809)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "19449125;32543654", "class_list": "", "function": "Endoplasmic reticulum (ER) calcium-selective channel preventing intracellular Ca2(+) stores from overfilling and maintaining calcium homeostasis in the ER. In response to endoplasmic reticulum (ER) Ca2(+) overloading, assembles into a homotetramer, forming a functional calcium-selective channel facilitating Ca2(+) release. Mediates ER Ca2(+) homeostasis in osteoblasts and plays a key role in bone formation, via the CaMKII-HDAC4-RUNX2 signaling axis. Component of the multi-pass translocon (MPT) complex that mediates insertion of multi-pass membrane proteins into the lipid bilayer of membranes. The MPT complex takes over after the SEC61 complex: following membrane insertion of the first few transmembrane segments of proteins by the SEC61 complex, the MPT complex occludes the lateral gate of the SEC61 complex to promote insertion of subsequent transmembrane regions. Within the MPT complex, the GEL subcomplex may mediate insertion of transmembrane regions into the membrane., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005262 calcium channel activity;GO:0043022 ribosome binding", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005783 endoplasmic reticulum;GO:0031966 mitochondrial membrane", "go_biological_process": "GO:0001503 ossification;GO:0070588 calcium ion transmembrane transport;GO:0006983 ER overload response;GO:0032469 endoplasmic reticulum calcium ion homeostasis;GO:0160063 multi-pass transmembrane protein insertion into ER membrane", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "C5HGF3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A8D1W095-1", "uniprot_id": "A0A8D1W095_PIG", "mass": 70624.0, "length": 630, "protein_name": "A-type voltage-gated potassium channel KCND2", "gene_name": "KCND2", "organism": "Pig", "refseq_name": "potassium voltage-gated channel subfamily D member 2", "refseq_ac": "XP_020934450", "gene_names_uniprotkb": "KCND2", "gene_names_refseq": "KCND2", "protein_names_uniprotkb": "A-type voltage-gated potassium channel KCND2; Potassium voltage-gated channel subfamily D member 2; Voltage-gated potassium channel subunit Kv4.2", "protein_names_refseq": "potassium voltage-gated channel subfamily D member 2", "tax_id": 9823, "disease": "", "pathway": " (ssc:100512382); (R-SSC-1296072); (R-SSC-5576894)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A286ZW00", "ec_number_list": "", "go_molecular_function": "GO:0046872 metal ion binding;GO:1905030 voltage-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential;GO:0005250 A-type (transient outward) potassium channel activity", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0098982 GABA-ergic synapse;GO:0043025 neuronal cell body;GO:0043197 dendritic spine;GO:0043204 perikaryon", "go_biological_process": "GO:0006936 muscle contraction;GO:0019228 neuronal action potential;GO:0051260 protein homooligomerization;GO:0001508 action potential;GO:0019233 sensory perception of pain", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A8D1W095-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A8W4F6I2-1", "uniprot_id": "A0A8W4F6I2_PIG", "mass": 112944.0, "length": 1005, "protein_name": "Glutamate receptor", "gene_name": "GRID2", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "GRID2", "gene_names_refseq": "", "protein_names_uniprotkb": "Glutamate receptor", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Member of the ionotropic glutamate receptor family, which plays a crucial role in synaptic organization and signal transduction in the central nervous system. Although it shares structural features with ionotropic glutamate receptors, does not bind glutamate as a primary ligand. Promotes synaptogenesis and mediates the D-Serine-dependent long term depression signals and AMPA receptor endocytosis of cerebellar parallel fiber-Purkinje cell (PF-PC) synapses through the NRX1B-CBLN1-GRID2 triad complex. In the presence of neurexins and cerebellins, forms cation-selective channels that are proposed to be gated by glycine and D-serine. However, recent research disputes this ligand-gated cation channel activity. Cation-selective ion channel activity can be triggered by GRM1 in Purkinje cells., [UniProtKB, UniProtKB]; Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0030165 PDZ domain binding;GO:0097110 scaffold protein binding;GO:1904315 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential;GO:0004971 AMPA glutamate receptor activity;GO:0015276 ligand-gated monoatomic ion channel activity", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0005886 plasma membrane;GO:0043197 dendritic spine;GO:0032281 AMPA glutamate receptor complex;GO:0098839 postsynaptic density membrane", "go_biological_process": "GO:1904861 excitatory synapse assembly;GO:0035249 synaptic transmission, glutamatergic;GO:0051965 positive regulation of synapse assembly;GO:0050804 modulation of chemical synaptic transmission;GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A8W4F6I2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A8W4FBM7-1", "uniprot_id": "A0A8W4FBM7_PIG", "mass": 137053.0, "length": 1306, "protein_name": "Heart development protein with EGF like domains 1", "gene_name": "HEG1", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "HEG1", "gene_names_refseq": "", "protein_names_uniprotkb": "Heart development protein with EGF like domains 1", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 4, "predicted_n_glycosites": 0, "predicted_o_glycosites": 4, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005911 cell-cell junction;GO:0009897 external side of plasma membrane", "go_biological_process": "GO:0007507 heart development;GO:0035024 negative regulation of Rho protein signal transduction;GO:1902414 protein localization to cell junction;GO:1905709 negative regulation of membrane permeability", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A8W4FBM7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A8W4F7H6-1", "uniprot_id": "A0A8W4F7H6_PIG", "mass": 46839.0, "length": 442, "protein_name": "POU domain protein", "gene_name": "POU3F2", "organism": "Pig", "refseq_name": "POU domain, class 3, transcription factor 2", "refseq_ac": "XP_001926276", "gene_names_uniprotkb": "POU3F2", "gene_names_refseq": "POU3F2", "protein_names_uniprotkb": "POU domain protein", "protein_names_refseq": "POU domain, class 3, transcription factor 2", "tax_id": 9823, "disease": "", "pathway": " (ssc:100157279)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0042802 identical protein binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005667 transcription regulator complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0010629 negative regulation of gene expression;GO:0007420 brain development;GO:0048666 neuron development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A8W4F7H6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1RM38-1", "uniprot_id": "F1RM38_PIG", "mass": 17393.0, "length": 155, "protein_name": "Multifunctional fusion protein", "gene_name": "FGF1", "organism": "Pig", "refseq_name": "fibroblast growth factor 1", "refseq_ac": "XP_003124058", "gene_names_uniprotkb": "FGF1", "gene_names_refseq": "AFGF; ECGF; FGF-1; FGF1; HBGF-1", "protein_names_uniprotkb": "Multifunctional fusion protein; Acidic fibroblast growth factor; Heparin-binding growth factor 1", "protein_names_refseq": "Heparin-binding growth factor 1; acidic fibroblast growth factor; endothelial cell growth factor; fibroblast growth factor 1", "tax_id": 9823, "disease": "", "pathway": " (ssc:397497); (R-SSC-109704); (R-SSC-1257604); (R-SSC-190322); (R-SSC-190370); (R-SSC-190373); (R-SSC-5654219); (R-SSC-5654228); (R-SSC-5654687); (R-SSC-5654688); (R-SSC-5654689); (R-SSC-5654693); (R-SSC-5654712); (R-SSC-5654719); (R-SSC-5654720); (R-SSC-5654726); (R-SSC-5654733); (R-SSC-5673001); (R-SSC-6811558)", "pathway_count": 19, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integrins and FGFR1 are essential for FGF1 signaling., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008201 heparin binding;GO:0008083 growth factor activity;GO:0005178 integrin binding;GO:0044548 S100 protein binding;GO:0005104 fibroblast growth factor receptor binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0005634 nucleus;GO:0005829 cytosol;GO:0005938 cell cortex;GO:0005615 extracellular space", "go_biological_process": "GO:0001525 angiogenesis;GO:0030154 cell differentiation;GO:0051781 positive regulation of cell division;GO:1903672 positive regulation of sprouting angiogenesis;GO:0008284 positive regulation of cell population proliferation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1RM38-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A8W4FFX3-1", "uniprot_id": "A0A8W4FFX3_PIG", "mass": 302835.0, "length": 2652, "protein_name": "Serine/threonine-protein kinase ATR", "gene_name": "ATR", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "ATR", "gene_names_refseq": "", "protein_names_uniprotkb": "Serine/threonine-protein kinase ATR; 2.7.11.1; Ataxia telangiectasia and Rad3-related protein", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-176187); (R-SSC-5685938); (R-SSC-5693607); (R-SSC-6783310); (R-SSC-6804756); (R-SSC-69473)", "pathway_count": 6, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0003677 DNA binding;GO:0032405 MutLalpha complex binding;GO:0032407 MutSalpha complex binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005635 nuclear envelope;GO:0005694 chromosome;GO:0070310 ATR-ATRIP complex;GO:0016605 PML body", "go_biological_process": "GO:0006281 DNA repair;GO:0006260 DNA replication;GO:0000077 DNA damage checkpoint signaling;GO:0000723 telomere maintenance;GO:0009612 response to mechanical stimulus", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A8W4FFX3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A8W4F8K8-1", "uniprot_id": "A0A8W4F8K8_PIG", "mass": 82713.0, "length": 744, "protein_name": "ATP binding cassette subfamily D member 1", "gene_name": "ABCD1", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "ABCD1", "gene_names_refseq": "", "protein_names_uniprotkb": "ATP binding cassette subfamily D member 1", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (ssc:100519529); (R-SSC-1369062); (R-SSC-2046105); (R-SSC-2046106); (R-SSC-390247); (R-SSC-9603798)", "pathway_count": 6, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005324 long-chain fatty acid transmembrane transporter activity;GO:0005524 ATP binding;GO:0019899 enzyme binding;GO:0042626 ATPase-coupled transmembrane transporter activity;GO:0042803 protein homodimerization activity", "go_cellular_component": "GO:0005778 peroxisomal membrane;GO:0031966 mitochondrial membrane;GO:0048471 perinuclear region of cytoplasm;GO:0005765 lysosomal membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:1903427 negative regulation of reactive oxygen species biosynthetic process;GO:0051900 regulation of mitochondrial depolarization;GO:0006635 fatty acid beta-oxidation;GO:0032000 positive regulation of fatty acid beta-oxidation;GO:0042760 very long-chain fatty acid catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A8W4F8K8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1RKZ6-1", "uniprot_id": "F1RKZ6_PIG", "mass": 128999.0, "length": 1109, "protein_name": "Ubiquitin carboxyl-terminal hydrolase 7", "gene_name": "USP7", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "USP7", "gene_names_refseq": "", "protein_names_uniprotkb": "Ubiquitin carboxyl-terminal hydrolase 7; 3.4.19.12; Deubiquitinating enzyme 7; Herpesvirus-associated ubiquitin-specific protease; Ubiquitin thioesterase 7; Ubiquitin-specific-processing protease 7", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-5689880); (R-SSC-6781823); (R-SSC-6782135); (R-SSC-6782210); (R-SSC-6804757); (R-SSC-8866652); (R-SSC-8948747)", "pathway_count": 7, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004843 cysteine-type deubiquitinase activity;GO:0002039 p53 binding;GO:0004197 cysteine-type endopeptidase activity;GO:1990380 K48-linked deubiquitinase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0016605 PML body;GO:0005694 chromosome;GO:0005634 nucleus;GO:0005829 cytosol", "go_biological_process": "GO:0006508 proteolysis;GO:0016579 protein deubiquitination;GO:0031647 regulation of protein stability;GO:0006307 DNA alkylation repair;GO:0050821 protein stabilization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1RKZ6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A8W4FB62-1", "uniprot_id": "A0A8W4FB62_PIG", "mass": 44056.0, "length": 390, "protein_name": "Apolipoprotein A-V", "gene_name": "APOA5", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "APOA5", "gene_names_refseq": "", "protein_names_uniprotkb": "Apolipoprotein A-V; Apolipoprotein A5", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-381426); (R-SSC-8957275); (R-SSC-8963901)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Minor apolipoprotein mainly associated with HDL and to a lesser extent with VLDL. May also be associated with chylomicrons. Important determinant of plasma triglyceride (TG) levels by both being a potent stimulator of apo-CII lipoprotein lipase (LPL) TG hydrolysis and an inhibitor of the hepatic VLDL-TG production rate (without affecting the VLDL-apoB production rate). Activates poorly lecithin:cholesterol acyltransferase (LCAT) and does not enhance efflux of cholesterol from macrophages. Binds heparin., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005543 phospholipid binding;GO:0008201 heparin binding;GO:0050750 low-density lipoprotein particle receptor binding;GO:0031210 phosphatidylcholine binding;GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity", "go_cellular_component": "GO:0005769 early endosome;GO:0005794 Golgi apparatus;GO:0034364 high-density lipoprotein particle;GO:0005770 late endosome;GO:0034361 very-low-density lipoprotein particle", "go_biological_process": "GO:0008203 cholesterol metabolic process;GO:0010898 positive regulation of triglyceride catabolic process;GO:0033700 phospholipid efflux;GO:0042157 lipoprotein metabolic process;GO:0033344 cholesterol efflux", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A8W4FB62-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A8W4FFH5-1", "uniprot_id": "A0A8W4FFH5_PIG", "mass": 397857.0, "length": 3697, "protein_name": "Laminin subunit alpha-5", "gene_name": "LAMA5", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "LAMA5", "gene_names_refseq": "", "protein_names_uniprotkb": "Laminin subunit alpha-5; Laminin-10 subunit alpha; Laminin-11 subunit alpha; Laminin-15 subunit alpha", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005178 integrin binding;GO:0048018 receptor ligand activity;GO:0005201 extracellular matrix structural constituent", "go_cellular_component": "GO:0005576 extracellular region;GO:0043259 laminin-10 complex;GO:0098978 glutamatergic synapse;GO:0005615 extracellular space;GO:0031594 neuromuscular junction", "go_biological_process": "GO:0048731 system development;GO:0007155 cell adhesion;GO:0016477 cell migration;GO:0030155 regulation of cell adhesion;GO:0009887 animal organ morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A8W4FFH5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A8W4FDJ8-1", "uniprot_id": "A0A8W4FDJ8_PIG", "mass": 31333.0, "length": 277, "protein_name": "tRNA (guanine-N(7)-)-methyltransferase", "gene_name": "METTL1", "organism": "Pig", "refseq_name": "tRNA (guanine-N(7)-)-methyltransferase", "refseq_ac": "XP_003360786", "gene_names_uniprotkb": "METTL1", "gene_names_refseq": "METTL1", "protein_names_uniprotkb": "tRNA (guanine-N(7)-)-methyltransferase; 2.1.1.33; Methyltransferase-like protein 1; tRNA (guanine(46)-N(7))-methyltransferase; tRNA(m7G46)-methyltransferase", "protein_names_refseq": "tRNA (guanine-N(7)-)-methyltransferase", "tax_id": 9823, "disease": "", "pathway": " (ssc:100622469)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA., [UniProtKB, HAMAP]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0000049 tRNA binding;GO:0008176 tRNA (guanine(46)-N7)-methyltransferase activity;GO:0160090 internal mRNA (guanine-N7-)-methyltransferase activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0043527 tRNA methyltransferase complex;GO:0106143 tRNA (m7G46) methyltransferase complex", "go_biological_process": "GO:0036265 RNA (guanine-N7)-methylation;GO:0030488 tRNA methylation;GO:0033554 cellular response to stress;GO:0036416 tRNA stabilization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A8W4FDJ8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A8W4FE93-1", "uniprot_id": "A0A8W4FE93_PIG", "mass": 53186.0, "length": 515, "protein_name": "Insulinoma-associated protein 1", "gene_name": "INSM1", "organism": "Pig", "refseq_name": "insulinoma-associated protein 1", "refseq_ac": "XP_020933075", "gene_names_uniprotkb": "INSM1", "gene_names_refseq": "INSM1", "protein_names_uniprotkb": "Insulinoma-associated protein 1; Zinc finger protein IA-1", "protein_names_refseq": "insulinoma-associated protein 1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100511966)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, 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binding;GO:0031490 chromatin DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0017053 transcription repressor complex", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0008285 negative regulation of cell population proliferation;GO:0045597 positive regulation of cell differentiation;GO:0030182 neuron differentiation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A8W4FE93-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A8W4FEV2-1", "uniprot_id": "A0A8W4FEV2_PIG", "mass": 50066.0, "length": 446, "protein_name": "Retinoic acid receptor beta", "gene_name": "RARB", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "RARB", "gene_names_refseq": "", "protein_names_uniprotkb": "Retinoic acid receptor beta; Nuclear receptor subfamily 1 group B member 2", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", 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0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0035259 nuclear glucocorticoid receptor binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0004879 nuclear receptor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005667 transcription regulator complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0048566 embryonic digestive tract development;GO:0048384 retinoic acid receptor signaling pathway;GO:0071376 cellular response to corticotropin-releasing hormone stimulus", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A8W4FEV2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A8W4FHG1-1", "uniprot_id": "A0A8W4FHG1_PIG", "mass": 53683.0, "length": 472, "protein_name": "Ribosome biogenesis protein NOP53", "gene_name": "NOP53", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "NOP53", "gene_names_refseq": "", "protein_names_uniprotkb": "Ribosome biogenesis protein NOP53", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "May play a role in ribosome biogenesis., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0042802 identical protein binding;GO:0002039 p53 binding;GO:0008097 5S rRNA binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005829 cytosol;GO:0001650 fibrillar center;GO:0033553 rDNA heterochromatin", "go_biological_process": "GO:0000027 ribosomal large subunit assembly;GO:1902570 protein localization to nucleolus;GO:1903006 positive regulation of protein K63-linked deubiquitination;GO:1990173 protein localization to nucleoplasm;GO:0000122 negative regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A8W4FHG1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A8W4FFC7-1", "uniprot_id": "A0A8W4FFC7_PIG", "mass": 22662.0, "length": 200, "protein_name": "Transmembrane p24 trafficking protein 2", "gene_name": "TMED2", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "TMED2", "gene_names_refseq": "", "protein_names_uniprotkb": "Transmembrane p24 trafficking protein 2", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-1912420); (R-SSC-204005); (R-SSC-5694530); (R-SSC-6807878); (R-SSC-6811434)", "pathway_count": 5, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0030134 COPII-coated ER to Golgi transport vesicle;GO:0005789 endoplasmic reticulum membrane;GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport;GO:0007030 Golgi organization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A8W4FFC7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A8W4FJW8-1", "uniprot_id": "A0A8W4FJW8_PIG", "mass": 107852.0, "length": 1009, "protein_name": "Trifunctional purine biosynthetic protein adenosine-3", "gene_name": "GART", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "GART", "gene_names_refseq": "", "protein_names_uniprotkb": "Trifunctional purine biosynthetic protein adenosine-3; 5'-phosphoribosylglycinamide transformylase; AIR synthase; AIRS; GAR transformylase; GARS; GART; Glycinamide ribonucleotide synthetase; Phosphoribosyl-aminoimidazole synthetase; Phosphoribosylglycinamide synthetase", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-73817)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Trifunctional enzyme that catalyzes three distinct reactions as part of the 'de novo' inosine monophosphate biosynthetic pathway., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0004637 phosphoribosylamine-glycine ligase activity;GO:0004641 phosphoribosylformylglycinamidine cyclo-ligase activity;GO:0004644 phosphoribosylglycinamide formyltransferase activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0009113 purine nucleobase biosynthetic process;GO:0006164 purine nucleotide biosynthetic process;GO:0006177 GMP biosynthetic process;GO:0006189 'de novo' IMP biosynthetic process;GO:0044208 'de novo' AMP biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A8W4FJW8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A8W4FHN1-1", "uniprot_id": "A0A8W4FHN1_PIG", "mass": 275820.0, "length": 2452, "protein_name": "Acetyl-CoA carboxylase 1", "gene_name": "ACACB", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "ACACB", "gene_names_refseq": "", "protein_names_uniprotkb": "Acetyl-CoA carboxylase 1; 6.4.1.2; ACC-alpha", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-196780); (R-SSC-200425)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Cytosolic enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the first and rate-limiting step of de novo fatty acid biosynthesis. This is a 2 steps reaction starting with the ATP-dependent carboxylation of the biotin carried by the biotin carboxyl carrier (BCC) domain followed by the transfer of the carboxyl group from carboxylated biotin to acetyl-CoA., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0042802 identical protein binding;GO:0046872 metal ion binding;GO:0003989 acetyl-CoA carboxylase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005739 mitochondrion;GO:0005741 mitochondrial outer membrane", "go_biological_process": "GO:0051289 protein homotetramerization;GO:0006084 acetyl-CoA metabolic process;GO:0006633 fatty acid biosynthetic process;GO:0010884 positive regulation of lipid storage;GO:0010906 regulation of glucose metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A8W4FHN1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A8W4FIU6-1", "uniprot_id": "A0A8W4FIU6_PIG", "mass": 36095.0, "length": 335, "protein_name": "Transcription factor Jun", "gene_name": "JUN", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "JUN", "gene_names_refseq": "", "protein_names_uniprotkb": "Transcription factor Jun; Activator protein 1; Proto-oncogene c-Jun; Transcription factor AP-1 subunit Jun; V-jun avian sarcoma virus 17 oncogene homolog", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-2559580); (R-SSC-2871796); (R-SSC-450341); (R-SSC-9018519)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003682 chromatin binding;GO:0005096 GTPase activator activity;GO:0042802 identical protein binding;GO:0031625 ubiquitin protein ligase binding;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0017053 transcription repressor complex;GO:0005667 transcription regulator complex;GO:0000791 euchromatin;GO:0035976 transcription factor AP-1 complex", "go_biological_process": "GO:0019046 release from viral latency;GO:0006351 DNA-templated transcription;GO:0042127 regulation of cell population proliferation;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0007254 JNK cascade", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A8W4FIU6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A8W4FNG2-1", "uniprot_id": "A0A8W4FNG2_PIG", "mass": 96338.0, "length": 866, "protein_name": "Chloride channel protein", "gene_name": "CLCN3", "organism": "Pig", "refseq_name": "H(+)/Cl(-) exchange transporter 3 isoform X1", "refseq_ac": "XP_005670544", "gene_names_uniprotkb": "CLCN3", "gene_names_refseq": "CLCN3", "protein_names_uniprotkb": "Chloride channel protein", "protein_names_refseq": "H(+)/Cl(-) exchange transporter 3 isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100156049)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Strongly outwardly rectifying, electrogenic H(+)/Cl(-)exchanger which mediates the exchange of chloride ions against protons. The CLC channel family contains both chloride channels and proton-coupled anion transporters that exchange chloride or another anion for protons. The presence of conserved gating glutamate residues is typical for family members that function as antiporters., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0072320 volume-sensitive chloride channel activity;GO:0005524 ATP binding;GO:0030165 PDZ domain binding;GO:0005247 voltage-gated chloride channel activity;GO:0062158 chloride:proton antiporter activity", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0098982 GABA-ergic synapse;GO:0005769 early endosome;GO:0005794 Golgi apparatus;GO:0005886 plasma membrane", "go_biological_process": "GO:0045794 negative regulation of cell volume;GO:0097401 synaptic vesicle lumen acidification", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A8W4FNG2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0AAS4-1", "uniprot_id": "SMS1_PIG", "mass": 48984.0, "length": 418, "protein_name": "Phosphatidylcholine:ceramide cholinephosphotransferase 1", "gene_name": "SGMS1", "organism": "Pig", "refseq_name": "phosphatidylcholine:ceramide cholinephosphotransferase 1", "refseq_ac": "NP_001090907", "gene_names_uniprotkb": "SGMS1; SMS1", "gene_names_refseq": "SGMS1; SMS1", "protein_names_uniprotkb": "Phosphatidylcholine:ceramide cholinephosphotransferase 1; 2.7.8.27; Sphingomyelin synthase 1", "protein_names_refseq": "phosphatidylcholine:ceramide cholinephosphotransferase 1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100037303); (R-SSC-1660661)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "17156943;32543654;34452438", "class_list": "", "function": "A Genome-Wide CRISPR/Cas9 Screen Reveals the Requirement of Host Sphingomyelin Synthase 1 for Infection with Pseudorabies Virus Mutant gD(-)Pass. Publication Status: Online-Only, [RefSeq, PubMed]; Major sphingomyelin synthase at the Golgi apparatus. Catalyzes the reversible transfer of phosphocholine moiety in sphingomyelin biosynthesis: in the forward reaction transfers phosphocholine head group of phosphatidylcholine (PC) on to ceramide (CER) to form ceramide phosphocholine (sphingomyelin, SM) and diacylglycerol (DAG) as by-product, and in the reverse reaction transfers phosphocholine from SM to DAG to form PC and CER. The direction of the reaction depends on the levels of CER and DAG in Golgi membranes. Converts the newly synthesized CER, that is transported from the endoplasmic reticulum to the trans-Golgi by the Cer transport protein (CERT), to SM. Can form a heteromeric complex with glucosylceramide synthase (GCS) increasing SMS activity and reducing glucosylceramide synthesis, a critical mechanism that controls the metabolic fate of CER in the Golgi (By similarity). Does not use free phosphorylcholine or CDP-choline as donor. Can also transfer phosphoethanolamine head group of phosphatidylethanolamine (PE) on to CER to form ceramide phosphoethanolamine (CPE) (By similarity). Regulates receptor-mediated signal transduction via mitogenic DAG and proapoptotic CER, as well as via SM, a structural component of membrane rafts that serve as platforms for signal transduction and protein sorting. Plays a role in secretory transport via regulation of DAG pool at the Golgi apparatus and its downstream effects on PRKD1 (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0002950 ceramide phosphoethanolamine synthase activity;GO:0033188 sphingomyelin synthase activity;GO:0047493 ceramide cholinephosphotransferase activity;GO:0016301 kinase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005886 plasma membrane;GO:0005789 endoplasmic reticulum membrane;GO:1990676 Golgi trans cisterna membrane", "go_biological_process": "GO:0006686 sphingomyelin biosynthetic process;GO:0046513 ceramide biosynthetic process;GO:0006915 apoptotic process;GO:0006665 sphingolipid metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0AAS4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0P8Z4-1", "uniprot_id": "NR6A1_PIG", "mass": 54350.0, "length": 479, "protein_name": "Nuclear receptor subfamily 6 group A member 1", "gene_name": "NR6A1", "organism": "Pig", "refseq_name": "nuclear receptor subfamily 6 group A member 1", "refseq_ac": "NP_001090968", "gene_names_uniprotkb": "NR6A1; GCNF", "gene_names_refseq": "GCNF; NR6A1", "protein_names_uniprotkb": "Nuclear receptor subfamily 6 group A member 1; GCNF; Germ cell nuclear factor", "protein_names_refseq": "germ cell nuclear factor; nuclear receptor subfamily 6 group A member 1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100038028)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "17416745;19220230;25134014;29774581;30741434;37703114", "class_list": "", "function": "Domestic and wild-type alleles at the MC1R and the NR6A1 genes were present in both domestic and wild populations. Findings of the distribution of MC1R alleles might be useful for tracing back the complex genetic history of autochthonous breeds., [RefSeq, PubMed]; NR6A1, PLAG1 and VRTN are significantly associated with the number of vertebrae in Chinese Tongcheng x Large White crossbred pigs, [RefSeq, PubMed]; Orphan nuclear receptor that binds to a response element containing the sequence 5'-TCAAGGTCA-3'. Acts as a regulator of embryonic stem cell pluripotency by mediating repression of POU5F1/OCT4: binds to the DR0 element within the POU5F1/OCT4 promoter and inhibits POU5F1/OCT4 expression during embryonic stem cell differentiation. Involved in the regulation of gene expression in germ cell development during gametogenesis., [UniProtKB, UniProtKB]; Recent studies suggest that a missense substitution (p.Pro192Leu) in the nuclear receptor subfamily 6, group A, member 1 (NR6A1) gene, mapped on porcine chromosome 1, is the causative mutation of a QTL affecting the number of vertebrae in pigs., [RefSeq, PubMed]; The selected genes NR6A1, RSAD2-CMPK2, and COL3A1 contribute to body size variation in Meishan pigs through different patterns., [RefSeq, PubMed]; This study supports the assumption that the Western NR6A1 haplotypes were introduced into Licha Black and possibly Laiwu and are associated with increased vertebral number, [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0034056 estrogen response element binding;GO:0008270 zinc ion binding;GO:0004879 nuclear receptor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0000785 chromatin", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0007283 spermatogenesis;GO:0030154 cell differentiation;GO:2000741 positive regulation of mesenchymal stem cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "A0P8Z4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0P8Z5-1", "uniprot_id": "UIMC1_PIG", "mass": 79863.0, "length": 721, "protein_name": "BRCA1-A complex subunit RAP80", "gene_name": "UIMC1", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "UIMC1; RAP80", "gene_names_refseq": "", "protein_names_uniprotkb": "BRCA1-A complex subunit RAP80; Receptor-associated protein 80; Ubiquitin interaction motif-containing protein 1", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (ssc:100037949)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "17416745", "class_list": "", "function": "Ubiquitin-binding protein. Specifically recognizes and binds 'Lys-63'-linked ubiquitin. Plays a central role in the BRCA1-A complex by specifically binding 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). The BRCA1-A complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX. Also weakly binds monoubiquitin but with much less affinity than 'Lys-63'-linked ubiquitin. May interact with monoubiquitinated histones H2A and H2B; the relevance of such results is however unclear in vivo. Does not bind Lys-48'-linked ubiquitin. May indirectly act as a transcriptional repressor by inhibiting the interaction of NR6A1 with the corepressor NCOR1., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 12, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0042393 histone binding;GO:0070530 K63-linked polyubiquitin modification-dependent protein binding", "go_cellular_component": "GO:0005634 nucleus;GO:0070531 BRCA1-A complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006302 double-strand break repair;GO:0010212 response to ionizing radiation;GO:0045739 positive regulation of DNA repair;GO:0006325 chromatin organization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0P8Z5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0PFK7-2", "uniprot_id": "CAPZB_PIG", "mass": 30629.0, "length": 272, "protein_name": "F-actin-capping protein subunit beta", "gene_name": "CAPZB", "organism": "Pig", "refseq_name": "F-actin-capping protein subunit beta", "refseq_ac": "NP_001106915", "gene_names_uniprotkb": "CAPZB", "gene_names_refseq": "CAPZB", "protein_names_uniprotkb": "F-actin-capping protein subunit beta; CapZ beta", "protein_names_refseq": "CP beta1; F-actin capping protein beta subunit; F-actin capping protein subunit beta 1; F-actin-capping protein subunit beta; capZ beta; capping actin protein of muscle Z-line beta subunit; capping protein (actin filament) muscle Z-line, beta", "tax_id": 9823, "disease": "", "pathway": " (ssc:100134958)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "17939027;19597856;24792893;25814576;29420470;30723633;33734450;36071160", "class_list": "", "function": "CAPZB, ANKRD1, and CTBP2 are promoted as candidate genes for meat quality that provide a link between signal pathways., [RefSeq, PubMed]; Data presented in our study suggests that the CAPZB gene may be a candidate gene of meat production trait and provides useful information for further studies on its roles in porcine skeletal muscle., [RefSeq, PubMed]; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. Plays a role in the regulation of cell morphology and cytoskeletal organization (By similarity). Forms, with CAPZB, the barbed end of the fast growing ends of actin filaments in the dynactin complex and stabilizes dynactin structure. The dynactin multiprotein complex activates the molecular motor dynein for ultra-processive transport along microtubules (PubMed:25814576, PubMed:29420470, PubMed:33734450, PubMed:36071160). Plays a role in the regulation of cell morphology and cytoskeletal organization (By similarity)., [UniProtKB, PubMed, UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A286ZU64;A9XFX6;F1SUN9", "ec_number_list": "", "go_molecular_function": "GO:0003779 actin binding", "go_cellular_component": "GO:0015629 actin cytoskeleton;GO:0008290 F-actin capping protein complex;GO:0030017 sarcomere;GO:0071203 WASH complex", "go_biological_process": "GO:0030036 actin cytoskeleton organization;GO:0051016 barbed-end actin filament capping;GO:0007017 microtubule-based process", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "A0PFK7-2", "record_type": "protein" }, { "uniprot_canonical_ac": "A1XQR9-1", "uniprot_id": "RUXE_PIG", "mass": 10818.0, "length": 92, "protein_name": "Small nuclear ribonucleoprotein E", "gene_name": "SNRPE", "organism": "Pig", "refseq_name": "small nuclear ribonucleoprotein E", "refseq_ac": "NP_001090934", "gene_names_uniprotkb": "SNRPE", "gene_names_refseq": "SNRPE; Sm-E; SmE; snRNP-E", "protein_names_uniprotkb": "Small nuclear ribonucleoprotein E; Sm protein E; Sm-E; SmE; snRNP-E", "protein_names_refseq": "sm protein E; small nuclear ribonucleoprotein E", "tax_id": 9823, "disease": "", "pathway": " (ssc:100038330)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs. As part of the U7 snRNP it is involved in histone 3'-end processing., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding", "go_cellular_component": "GO:0005685 U1 snRNP;GO:0005634 nucleus;GO:0005829 cytosol;GO:0034709 methylosome;GO:0005686 U2 snRNP", "go_biological_process": "GO:0000387 spliceosomal snRNP assembly;GO:0000398 mRNA splicing, via spliceosome", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A1XQR9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A1XQS5-1", "uniprot_id": "AT5G1_PIG", "mass": 14274.0, "length": 136, "protein_name": "ATP synthase F(0) complex subunit C1, mitochondrial", "gene_name": "ATP5MC1", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "ATP5MC1; ATP5G1", "gene_names_refseq": "", "protein_names_uniprotkb": "ATP synthase F(0) complex subunit C1, mitochondrial; ATP synthase lipid-binding protein; ATP synthase membrane subunit c locus 1; ATP synthase proteolipid P1; ATPase protein 9; ATPase subunit c; Proton-conducting channel, ATP synthase F(0) complex subunit c", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Subunit c, of the mitochondrial membrane ATP synthase complex (F(1)F(0) ATP synthase or Complex V) that produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. ATP synthase complex consist of a soluble F(1) head domain - the catalytic core - and a membrane F(1) domain - the membrane proton channel. These two domains are linked by a central stalk rotating inside the F(1) region and a stationary peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. With the subunit a (MT-ATP6), forms the proton-conducting channel in the F(0) domain, that contains two crucial half-channels (inlet and outlet) that facilitate proton movement from the mitochondrial intermembrane space (IMS) into the matrix. Protons are taken up via the inlet half-channel and released through the outlet half-channel, following a Grotthuss mechanism., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008289 lipid binding;GO:0015252 proton channel activity", "go_cellular_component": "GO:0031966 mitochondrial membrane;GO:0045259 proton-transporting ATP synthase complex;GO:0033177 proton-transporting two-sector ATPase complex, proton-transporting domain", "go_biological_process": "GO:0015986 proton motive force-driven ATP synthesis;GO:1902600 proton transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A1XQS5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A1XQU5-1", "uniprot_id": "RL27_PIG", "mass": 15798.0, "length": 136, "protein_name": "Large ribosomal subunit protein eL27", "gene_name": "RPL27", "organism": "Pig", "refseq_name": "large ribosomal subunit protein eL27", "refseq_ac": "NP_001090948", "gene_names_uniprotkb": "RPL27", "gene_names_refseq": "RPL27", "protein_names_uniprotkb": "Large ribosomal subunit protein eL27; 60S ribosomal protein L27", "protein_names_refseq": "60S ribosomal protein L27; large ribosomal subunit protein eL27", "tax_id": 9823, "disease": "", "pathway": " (ssc:100037995); (R-SSC-156827); (R-SSC-1799339); (R-SSC-6791226); (R-SSC-72689); (R-SSC-72706); (R-SSC-975956); (R-SSC-975957); (R-SSC-9954709); (R-SSC-9954714); (R-SSC-9954716)", "pathway_count": 11, "publication_count": 1, "publication_id_list": "24930395", "class_list": "", "function": "Component of the large ribosomal subunit (PubMed:24930395). Required for proper rRNA processing and maturation of 28S and 5.8S rRNAs (By similarity)., [UniProtKB, UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0098556 cytoplasmic side of rough endoplasmic reticulum membrane;GO:0022625 cytosolic large ribosomal subunit;GO:0015934 large ribosomal subunit", "go_biological_process": "GO:0006412 translation;GO:0006364 rRNA processing", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A1XQU5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A1YIZ1-1", "uniprot_id": "SPS2_PIG", "mass": 47821.0, "length": 451, "protein_name": "Selenide, water dikinase 2", "gene_name": "SEPHS2", "organism": "Pig", "refseq_name": "selenide, water dikinase 2", "refseq_ac": "NP_001087204", "gene_names_uniprotkb": "SEPHS2; SPS2", "gene_names_refseq": "SEPHS2; SPS2", "protein_names_uniprotkb": "Selenide, water dikinase 2; 2.7.9.3; Selenium donor protein 2; Selenophosphate synthase 2", "protein_names_refseq": "selenide, water dikinase 2; selenium donor protein 2; selenophosphate synthase 2", "tax_id": 9823, "disease": "", "pathway": " (ssc:100037302); (R-SSC-2408557)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32869810", "class_list": "", "function": "Se deficiency induces renal pathological changes by regulating selenoprotein expression, disrupting redox balance, and activating inflammation., [RefSeq, PubMed]; Selenophosphate synthase that generates the selenium donor for selenocysteine biosynthesis by catalyzing formation of selenophosphate from selenide and ATP., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004756 selenide, water dikinase activity;GO:0005524 ATP binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0016260 selenocysteine biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A1YIZ1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A1YVX4-1", "uniprot_id": "KDM5C_PIG", "mass": 170584.0, "length": 1516, "protein_name": "Lysine-specific demethylase 5C", "gene_name": "KDM5C", "organism": "Pig", "refseq_name": "lysine-specific demethylase 5C", "refseq_ac": "NP_001090902", "gene_names_uniprotkb": "KDM5C; JARID1C; SMCX", "gene_names_refseq": "JARID1C; KDM5C; SMCX", "protein_names_uniprotkb": "Lysine-specific demethylase 5C; 1.14.11.67; Histone demethylase JARID1C; Jumonji/ARID domain-containing protein 1C; Protein SmcX; [histone H3]-trimethyl-L-lysine(4) demethylase 5C", "protein_names_refseq": "[histone H3]-trimethyl-L-lysine(4) demethylase 5C; histone demethylase JARID1C; jumonji, AT rich interactive domain 1C; jumonji/ARID domain-containing protein 1C; lysine (K)-specific demethylase 5C tv1; lysine-specific demethylase 5C; protein SmcX", "tax_id": 9823, "disease": "", "pathway": " (ssc:100037295)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "18155621", "class_list": "", "function": "Histone demethylase that specifically demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4'. Participates in transcriptional repression of neuronal genes by recruiting histone deacetylases and REST at neuron-restrictive silencer elements (By similarity)., [UniProtKB, UniProtKB]; The full-length cDNA of JARID1C has been cloned., [RefSeq, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0034647 histone H3K4me/H3K4me2/H3K4me3 demethylase activity;GO:0003677 DNA binding;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005634 nucleus;GO:0000785 chromatin", "go_biological_process": "GO:0006338 chromatin remodeling;GO:0006351 DNA-templated transcription;GO:0006355 regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A1YVX4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A2TF48-1", "uniprot_id": "MYD88_PIG", "mass": 33254.0, "length": 293, "protein_name": "Myeloid differentiation primary response protein MyD88", "gene_name": "MYD88", "organism": "Pig", "refseq_name": "myeloid differentiation primary response protein MyD88", "refseq_ac": "NP_001093393", "gene_names_uniprotkb": "MYD88", "gene_names_refseq": "MYD88", "protein_names_uniprotkb": "Myeloid differentiation primary response protein MyD88", "protein_names_refseq": "myeloid differentiation primary response 88; myeloid differentiation primary response gene (88); myeloid differentiation primary response protein MyD88", "tax_id": 9823, "disease": "", "pathway": " (ssc:396646)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "17330086;17976317;25380861;26581603", "class_list": "", "function": "Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Increases IL-8 transcription. Involved in IL-18-mediated signaling pathway. Activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, NOS2/INOS, and IL12A genes. Upon TLR8 activation by GU-rich single-stranded RNA (GU-rich RNA) derived from viruses, induces IL1B release through NLRP3 inflammasome activation (By similarity). MyD88-mediated signaling in intestinal epithelial cells is crucial for maintenance of gut homeostasis and controls the expression of the antimicrobial lectin REG3G in the small intestine (By similarity)., [UniProtKB, UniProtKB, UniProtKB]; At 30 days after autotransplantation of a pig kidney, mRNA expression increases for MyD88., [RefSeq, PubMed]; These results suggest that an MyD88-dependent signaling pathway is present in newborn as well as in adult swine and that it is involved in the innate immune system of these animals., [RefSeq, PubMed]; These results suggest that porcine circovirus 2 induces IL-8 secretion via the TLR2/MyD88/NF-kappaB signalling pathway., [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A7UL70;A8I488;B1B361;C6ZCT2", "ec_number_list": "", "go_molecular_function": "GO:0035325 Toll-like receptor binding;GO:0070976 TIR domain binding;GO:0005126 cytokine receptor binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005886 plasma membrane", "go_biological_process": "GO:0006954 inflammatory response;GO:0045087 innate immune response;GO:0050830 defense response to Gram-positive bacterium;GO:0051607 defense response to virus;GO:0043123 positive regulation of canonical NF-kappaB signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "A2TF48-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A4GVD1-1", "uniprot_id": "CXG1_PIG", "mass": 45598.0, "length": 396, "protein_name": "Gap junction gamma-1 protein", "gene_name": "GJC1", "organism": "Pig", "refseq_name": "gap junction gamma-1 protein", "refseq_ac": "NP_001090988", "gene_names_uniprotkb": "GJC1; GJA7", "gene_names_refseq": "GJA7; GJC1; cx45", "protein_names_uniprotkb": "Gap junction gamma-1 protein; Connexin-45; Cx45; Gap junction alpha-7 protein", "protein_names_refseq": "connexin 45; gap junction alpha-7 protein; gap junction gamma-1 protein; gap junction protein, alpha 7, 45kDa; gap junction protein, delta 3, 31.9kDa", "tax_id": 9823, "disease": "", "pathway": " (ssc:100048959); (R-SSC-112303); (R-SSC-190861)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Structural component of the gap junction, a specialized intercellular structure consisting of a cluster of closely packed pairs of transmembrane channels, the connexons, that allow passage of small molecules and electrical signals between neighboring cells. Forms homotypic and heterotypic channels gated by transjunctional voltage (By similarity). Involved in intercellular innate immune signaling. Mediates translocation of 2',3'-cGAMP and 2',5'-oligoadenylates (2-5A) second messengers from virus-infected cells to macrophages and uninfected neighboring cells to propagate and amplify the antiviral immune response (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005216 monoatomic ion channel activity;GO:0086077 gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling;GO:0005243 gap junction channel activity", "go_cellular_component": "GO:0005922 connexin complex", "go_biological_process": "GO:0007267 cell-cell signaling;GO:0045087 innate immune response;GO:0016264 gap junction assembly", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A4GVD1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A4Z6H0-1", "uniprot_id": "PURA1_PIG", "mass": 50098.0, "length": 457, "protein_name": "Adenylosuccinate synthetase isozyme 1", "gene_name": "ADSS1", "organism": "Pig", "refseq_name": "adenylosuccinate synthetase isozyme 1", "refseq_ac": "NP_001090978", "gene_names_uniprotkb": "ADSS1; ADSSL1", "gene_names_refseq": "ADSS1; ADSSL1", "protein_names_uniprotkb": "Adenylosuccinate synthetase isozyme 1; 6.3.4.4; AMPSase 1; AdSS 1; Adenylosuccinate synthetase, basic isozyme; Adenylosuccinate synthetase, muscle isozyme; IMP--aspartate ligase 1; M-type adenylosuccinate synthetase", "protein_names_refseq": "AMPSase 1; IMP--aspartate ligase 1; M-type adenylosuccinate synthetase; adenylosuccinate synthase like 1; adenylosuccinate synthetase isozyme 1; adenylosuccinate synthetase, basic isozyme; adenylosuccinate synthetase, muscle isozyme", "tax_id": 9823, "disease": "", "pathway": " (ssc:100048943)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "17347008", "class_list": "", "function": "Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0005525 GTP binding;GO:0004019 adenylosuccinate synthase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0046040 IMP metabolic process;GO:0044208 'de novo' AMP biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A4Z6H0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A4Z6H1-1", "uniprot_id": "PURA2_PIG", "mass": 50140.0, "length": 456, "protein_name": "Adenylosuccinate synthetase isozyme 2", "gene_name": "ADSS2", "organism": "Pig", "refseq_name": "adenylosuccinate synthetase isozyme 2", "refseq_ac": "NP_001090977", "gene_names_uniprotkb": "ADSS2; ADSS", "gene_names_refseq": "ADSS2", "protein_names_uniprotkb": "Adenylosuccinate synthetase isozyme 2; 6.3.4.4; AMPSase 2; AdSS 2; Adenylosuccinate synthetase, acidic isozyme; Adenylosuccinate synthetase, liver isozyme; IMP--aspartate ligase 2; L-type adenylosuccinate synthetase", "protein_names_refseq": "AMPSase 2; IMP--aspartate ligase 2; L-type adenylosuccinate synthetase; adSS 2; adenylosuccinate synthetase isozyme 2; adenylosuccinate synthetase, acidic isozyme; adenylosuccinate synthetase, liver isozyme", "tax_id": 9823, "disease": "", "pathway": " (ssc:100048942); (R-SSC-73817)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "17347008", "class_list": "", "function": "Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0005525 GTP binding;GO:0004019 adenylosuccinate synthase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion", "go_biological_process": "GO:0046040 IMP metabolic process;GO:0044208 'de novo' AMP biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A4Z6H1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A5A763-1", "uniprot_id": "SOX10_PIG", "mass": 50044.0, "length": 469, "protein_name": "Transcription factor SOX-10", "gene_name": "SOX10", "organism": "Pig", "refseq_name": "transcription factor SOX-10", "refseq_ac": "NP_001093403", "gene_names_uniprotkb": "SOX10", "gene_names_refseq": "SOX10", "protein_names_uniprotkb": "Transcription factor SOX-10", "protein_names_refseq": "SRY (sex determining region Y)-box 10; SRY-box 10; transcription factor SOX-10", "tax_id": 9823, "disease": "", "pathway": " (ssc:414903); (R-SSC-9856649)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "33766494", "class_list": "", "function": "Phenotypic similarities in pigs with SOX10(c.321dupC) and SOX10(c.325A>T) mutations implied the correlation of SOX10 haploinsufficiency with Waardenburg syndrome., [RefSeq, PubMed]; Transcription factor that plays a central role in developing and mature glia (By similarity). Specifically activates expression of myelin genes, during oligodendrocyte (OL) maturation, such as DUSP15 and MYRF, thereby playing a central role in oligodendrocyte maturation and CNS myelination (By similarity). Once induced, MYRF cooperates with SOX10 to implement the myelination program (By similarity). Transcriptional activator of MITF, acting synergistically with PAX3 (By similarity). Transcriptional activator of MBP, via binding to the gene promoter (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0003700 DNA-binding transcription factor activity;GO:0000976 transcription cis-regulatory region binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005741 mitochondrial outer membrane", "go_biological_process": "GO:0048484 enteric nervous system development;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0022010 central nervous system myelination;GO:0045893 positive regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A5A763-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A5A8Y3-1", "uniprot_id": "A5A8Y3_PIG", "mass": 19911.0, "length": 180, "protein_name": "E3 ubiquitin-protein ligase RNF", "gene_name": "RNF5", "organism": "Pig", "refseq_name": "E3 ubiquitin-protein ligase RNF5", "refseq_ac": "NP_001116696", "gene_names_uniprotkb": "RNF5", "gene_names_refseq": "RNF5", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase RNF; 2.3.2.27; RING finger protein", "protein_names_refseq": "E3 ubiquitin-protein ligase RNF5", "tax_id": 9823, "disease": "", "pathway": " (ssc:100144528); (R-SSC-382556); (R-SSC-9931269)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "E3 ubiquitin-protein ligase., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A4X1V593", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0042802 identical protein binding;GO:0044877 protein-containing complex binding;GO:0061630 ubiquitin protein ligase activity;GO:0044390 ubiquitin-like protein conjugating enzyme binding", "go_cellular_component": "GO:0031966 mitochondrial membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006511 ubiquitin-dependent protein catabolic process;GO:0036503 ERAD pathway;GO:0070936 protein K48-linked ubiquitination;GO:0070534 protein K63-linked ubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A5A8Y3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A5D9N3-1", "uniprot_id": "A5D9N3_PIG", "mass": 16695.0, "length": 147, "protein_name": "Allograft inflammatory factor 1", "gene_name": "AIF1", "organism": "Pig", "refseq_name": "allograft inflammatory factor 1", "refseq_ac": "NP_001123422", "gene_names_uniprotkb": "AIF1", "gene_names_refseq": "AIF-1; AIF1", "protein_names_uniprotkb": "Allograft inflammatory factor 1", "protein_names_refseq": "allograft inflammatory factor 1; daintain", "tax_id": 9823, "disease": "", "pathway": " (ssc:397271)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0051015 actin filament binding;GO:0005509 calcium ion binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0001891 phagocytic cup;GO:0005856 cytoskeleton;GO:0032587 ruffle membrane;GO:0005886 plasma membrane;GO:0042995 cell projection", "go_biological_process": "GO:0051017 actin filament bundle assembly;GO:0097178 ruffle assembly", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A5D9N3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A7VK00-1", "uniprot_id": "MX2_PIG", "mass": 80327.0, "length": 711, "protein_name": "Interferon-induced GTP-binding protein Mx2", "gene_name": "MX2", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "MX2", "gene_names_refseq": "", "protein_names_uniprotkb": "Interferon-induced GTP-binding protein Mx2; Myxovirus resistance protein 2", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-1169408)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "18062906;18977535", "class_list": "", "function": "Interferon-induced dynamin-like GTPase with antiviral activity against influenza virus A (FLUAV)., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0008017 microtubule binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005874 microtubule;GO:0005886 plasma membrane;GO:0045202 synapse", "go_biological_process": "GO:0045087 innate immune response;GO:0051607 defense response to virus;GO:0009615 response to virus;GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "A7VK00-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A8I499-1", "uniprot_id": "CTR2_PIG", "mass": 71458.0, "length": 657, "protein_name": "Cationic amino acid transporter 2", "gene_name": "SLC7A2", "organism": "Pig", "refseq_name": "cationic amino acid transporter 2", "refseq_ac": "NP_001103890", "gene_names_uniprotkb": "SLC7A2; ATRC2", "gene_names_refseq": "ATRC2; CAT-2; CAT2; SLC7A2", "protein_names_uniprotkb": "Cationic amino acid transporter 2; CAT-2; CAT2; Low affinity cationic amino acid transporter 2; Solute carrier family 7 member 2", "protein_names_refseq": "Low affinity cationic amino acid transporter 2; cationic amino acid transporter 2; solute carrier family 7 (cationic amino acid transporter, y+ system), member 2", "tax_id": 9823, "disease": "", "pathway": " (ssc:100037298)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Functions as a permease involved in the transport of the cationic amino acids (L-arginine, L-lysine, L-ornithine and L-homoarginine) (By similarity). May play a role in classical or alternative activation of macrophages via its role in arginine transport (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 4, "predicted_n_glycosites": 3, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "A1YRJ0", "ec_number_list": "", "go_molecular_function": "GO:0000064 L-ornithine transmembrane transporter activity;GO:0015189 L-lysine transmembrane transporter activity;GO:0061459 L-arginine transmembrane transporter activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0097638 L-arginine import across plasma membrane;GO:1903352 L-ornithine transmembrane transport;GO:1903826 L-arginine transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "A8I499-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A8W649-1", "uniprot_id": "AQP5_PIG", "mass": 28146.0, "length": 265, "protein_name": "Aquaporin-5", "gene_name": "AQP5", "organism": "Pig", "refseq_name": "aquaporin-5", "refseq_ac": "NP_001103894", "gene_names_uniprotkb": "AQP5", "gene_names_refseq": "AQP5", "protein_names_uniprotkb": "Aquaporin-5; AQP-5", "protein_names_refseq": "AQP-5; aquaporin-5", "tax_id": 9823, "disease": "", "pathway": " (ssc:100126278); (R-SSC-432047)", "pathway_count": 2, "publication_count": 7, "publication_id_list": "18824632;20828411;25317682;26661749;26988150;27226190;29532265", "class_list": "", "function": "A functional and distinctive collaboration exists among diverse AQPs in water handling during the different uterine phases in the estrous cycle and early pregnancy. Publication Status: Online-Only, [RefSeq, PubMed]; AQP1 and 5 seem to be crucial for follicular development in pigs, [RefSeq, PubMed]; Aquaporin 5 appears to be a potential regulator of follicular fluid accumulation, under androgen control, and may be a key factor in antral follicle growth, [RefSeq, PubMed]; Aquaporins form homotetrameric transmembrane channels, with each monomer independently mediating water transport across the plasma membrane along its osmotic gradient (By similarity). Plays an important role in fluid secretion in salivary glands (By similarity). Required for TRPV4 activation by hypotonicity. Together with TRPV4, controls regulatory volume decrease in salivary epithelial cells (By similarity). Seems to play a redundant role in water transport in the eye, lung and in sweat glands (By similarity)., [UniProtKB, UniProtKB, UniProtKB]; Quantitative real-time PCR analysis showed markedly decreased mRNA levels of AQP1 and AQP5 and Na,K-ATPase in the Porcine reproductive and respiratory syndrome virus (PRRSV) -infected pig lungs compared to those of uninfected pig lungs., [RefSeq, PubMed]; Several subtypes of the AQPs (AQP1, 5, and 9) are involved in regulation of water homeostasis in the reproductive system of gilts., [RefSeq, PubMed]; These results suggest a participation of steroid hormones (P4 and E2), AA derivatives and cAMP in controlling the expression of AQP1 and AQP5 as well as the distribution of AQP5 in the uterine tissue of pregnant gilts during placentation (Days 30 - 32 of gestation)., [RefSeq, PubMed]; Up-regulated by progesterone, estradiol, arachidonic acid, forskolin, and cyclic AMP in the uterus during the embryo implantation period, [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0042802 identical protein binding;GO:0015250 water channel activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005886 plasma membrane;GO:0016324 apical plasma membrane;GO:0030659 cytoplasmic vesicle membrane;GO:0005902 microvillus", "go_biological_process": "GO:0071476 cellular hypotonic response;GO:0051289 protein homotetramerization;GO:0030157 pancreatic juice secretion;GO:0042476 odontogenesis;GO:0006833 water transport", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "A8W649-1", "record_type": "protein" }, { "uniprot_canonical_ac": "B1PHQ8-1", "uniprot_id": "CML1_PIG", "mass": 41384.0, "length": 363, "protein_name": "Chemerin-like receptor 1", "gene_name": "CMLKR1", "organism": "Pig", "refseq_name": "chemerin-like receptor 1", "refseq_ac": "NP_001116572", "gene_names_uniprotkb": "CMLKR1", "gene_names_refseq": "CMKLR1; CMLKR1; GPCR", "protein_names_uniprotkb": "Chemerin-like receptor 1; Chemokine-like receptor 1", "protein_names_refseq": "chemerin-like receptor 1; chemokine-like receptor 1; seven transmembrane helix receptor", "tax_id": 9823, "disease": "", "pathway": " (ssc:780421); (R-SSC-373076)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "20663411", "class_list": "", "function": "Receptor for the chemoattractant adipokine chemerin/RARRES2 and for the omega-3 fatty acid derived molecule resolvin E1. Interaction with RARRES2 initiates activation of G proteins G(i)/G(o) and beta-arrestin pathways inducing cellular responses via second messenger pathways such as intracellular calcium mobilization, phosphorylation of MAP kinases MAPK1/MAPK3 (ERK1/2), TYRO3, MAPK14/P38MAPK and PI3K leading to multifunctional effects, like, reduction of immune responses, enhancing of adipogenesis and angionesis. Resolvin E1 down-regulates cytokine production in macrophages by reducing the activation of MAPK1/3 (ERK1/2) and NF-kappa-B. Positively regulates adipogenesis and adipocyte metabolism (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004875 complement receptor activity;GO:0004930 G protein-coupled receptor activity;GO:0097003 adipokinetic hormone receptor activity;GO:0097004 adipokinetic hormone binding", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0002430 complement receptor mediated signaling pathway;GO:0006935 chemotaxis;GO:0006954 inflammatory response;GO:0007186 G protein-coupled receptor signaling pathway;GO:0007204 positive regulation of cytosolic calcium ion concentration", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "B1PHQ8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "B2LYG4-1", "uniprot_id": "FITM2_PIG", "mass": 29633.0, "length": 262, "protein_name": "Acyl-coenzyme A diphosphatase FITM2", "gene_name": "FITM2", "organism": "Pig", "refseq_name": "acyl-coenzyme A diphosphatase FITM2", "refseq_ac": "NP_001121932", "gene_names_uniprotkb": "FITM2; FIT2", "gene_names_refseq": "FIT2; FITM2", "protein_names_uniprotkb": "Acyl-coenzyme A diphosphatase FITM2; 3.6.1.-; Fat storage-inducing transmembrane protein 2; Fat-inducing protein 2", "protein_names_refseq": "Fat-inducing protein 2; acyl-coenzyme A diphosphatase FITM2; fat-inducing transcript 2", "tax_id": 9823, "disease": "", "pathway": " (ssc:100158013); (R-SSC-8964572)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Fatty acyl-coenzyme A (CoA) diphosphatase that hydrolyzes fatty acyl-CoA to yield acyl-4'-phosphopantetheine and adenosine 3',5'-bisphosphate (By similarity). Preferentially hydrolyzes unsaturated long-chain acyl-CoA substrates such as oleoyl-CoA/(9Z)-octadecenoyl-CoA and arachidonoyl-CoA/(5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA in the endoplasmic reticulum (ER) lumen (By similarity). This catalytic activity is required for maintaining ER structure and for lipid droplets (LDs) biogenesis, which are lipid storage organelles involved in maintaining lipid and energy homeostasis (By similarity). Directly binds to diacylglycerol (DAGs) and triacylglycerol, which is also important for LD biogenesis (By similarity). May support directional budding of nacent LDs from the ER into the cytosol by reducing DAG levels at sites of LD formation (By similarity). Plays a role in the regulation of cell morphology and cytoskeletal organization (By similarity)., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0017129 triglyceride binding;GO:0019992 diacylglycerol binding;GO:0010945 coenzyme A diphosphatase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006641 triglyceride metabolic process;GO:0055088 lipid homeostasis;GO:0045444 fat cell differentiation;GO:0019915 lipid storage;GO:0034389 lipid droplet organization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "B2LYG4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "B2ZI34-1", "uniprot_id": "NMBR_PIG", "mass": 43328.0, "length": 390, "protein_name": "Neuromedin-B receptor", "gene_name": "NMBR", "organism": "Pig", "refseq_name": "neuromedin-B receptor", "refseq_ac": "NP_001121961", "gene_names_uniprotkb": "NMBR", "gene_names_refseq": "NMB-R; NMBR", "protein_names_uniprotkb": "Neuromedin-B receptor; NMB-R; Neuromedin-B-preferring bombesin receptor", "protein_names_refseq": "neuromedin-B receptor; neuromedin-B-preferring bombesin receptor", "tax_id": 9823, "disease": "", "pathway": " (ssc:100169653); (R-SSC-375276); (R-SSC-416476)", "pathway_count": 3, "publication_count": 2, "publication_id_list": "27010315;29632025", "class_list": "", "function": "In sow estrous cycle, the hypothalamic levels of both NMB and NMBR mRAN were similar, but the expression levels of the pituitary were negatively correlated. Publication Status: Online-Only, [RefSeq, PubMed]; Receptor for neuromedin-B (By similarity). Contributes to the maintenance of basal sigh rate through signaling in the pre-Botzinger complex, a cluster of several thousand neurons in the ventrolateral medulla responsible for inspiration during respiratory activity (By similarity). Contributes to the induction of sneezing following exposure to chemical irritants or allergens which causes release of NMB by nasal sensory neurons and activation of NMBR-expressing neurons in the sneeze-evoking region of the brainstem (By similarity). These in turn activate neurons of the caudal ventral respiratory group, giving rise to the sneezing response (By similarity). Contributes to induction of acute itch, possibly through its activation on dorsal root ganglion neurons by the NMB peptide (By similarity). Plays a role in the innate immune response to influenza A virus infection by enhancing interferon alpha expression and reducing expression of IL6 (By similarity). Plays a role in CSF1-induced proliferation of osteoclast precursors by contributing to the positive regulation of the expression of the CSF1 receptor CSF1R (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "A0A287BJR5", "ec_number_list": "", "go_molecular_function": "GO:0008188 neuropeptide receptor activity;GO:0004946 bombesin receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway;GO:0032715 negative regulation of interleukin-6 production;GO:0090290 positive regulation of osteoclast proliferation;GO:0140374 antiviral innate immune response;GO:0160023 sneeze reflex", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "B2ZI34-1", "record_type": "protein" }, { "uniprot_canonical_ac": "B8Y466-1", "uniprot_id": "SRPK3_PIG", "mass": 61905.0, "length": 566, "protein_name": "SRSF protein kinase 3", "gene_name": "SRPK3", "organism": "Pig", "refseq_name": "SRSF protein kinase 3", "refseq_ac": "NP_001137591", "gene_names_uniprotkb": "SRPK3; MSSK1; STK23", "gene_names_refseq": "MSSK-1; MSSK1; SRPK3; STK23", "protein_names_uniprotkb": "SRSF protein kinase 3; 2.7.11.1; MSSK-1; Muscle-specific serine kinase 1; SR-protein-specific kinase 3; Serine/arginine-rich protein-specific kinase 3; Serine/threonine-protein kinase 23", "protein_names_refseq": "Muscle-specific serine kinase 1; SFRS protein kinase 3; SR-protein-specific kinase 3; SRSF protein kinase 3; Serine/arginine-rich protein-specific kinase 3; Serine/threonine-protein kinase 23; Serine/threonine-protein kinase SRPK3; serine/arginine-rich protein specific kinase 3; serine/arginine-rich specific kinase 3", "tax_id": 9823, "disease": "", "pathway": " (ssc:100240720)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "20127522", "class_list": "", "function": "Results suggest that the SRPK3 gene might be an important gene of skeletal muscle development, [RefSeq, PubMed]; Serine/arginine-rich protein-specific kinase which specifically phosphorylates its substrates at serine residues located in regions rich in arginine/serine dipeptides, known as RS domains. Phosphorylates the SR splicing factor SRSF1 and the lamin-B receptor (LBR) in vitro. Required for normal muscle development (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0030154 cell differentiation;GO:0035556 intracellular signal transduction;GO:0007517 muscle organ development;GO:0000245 spliceosomal complex assembly;GO:0060537 muscle tissue development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "B8Y466-1", "record_type": "protein" }, { "uniprot_canonical_ac": "C3RZA1-1", "uniprot_id": "SMYD2_PIG", "mass": 49870.0, "length": 433, "protein_name": "N-lysine methyltransferase SMYD2", "gene_name": "SMYD2", "organism": "Pig", "refseq_name": "N-lysine methyltransferase SMYD2", "refseq_ac": "NP_001153563", "gene_names_uniprotkb": "SMYD2", "gene_names_refseq": "SMYD2", "protein_names_uniprotkb": "N-lysine methyltransferase SMYD2; 2.1.1.-; 2.1.1.354; Histone methyltransferase SMYD2; SET and MYND domain-containing protein 2", "protein_names_refseq": "Histone methyltransferase SMYD2; N-lysine methyltransferase SMYD2; SET and MYND domain-containing protein 2", "tax_id": 9823, "disease": "", "pathway": " (ssc:100294706)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "19133938", "class_list": "", "function": "Protein-lysine N-methyltransferase that methylates both histones and non-histone proteins, including p53/TP53 and RB1. Specifically trimethylates histone H3 'Lys-4' (H3K4me3) in vivo. The activity requires interaction with HSP90alpha. Shows even higher methyltransferase activity on p53/TP53. Monomethylates 'Lys-370' of p53/TP53, leading to decreased DNA-binding activity and subsequent transcriptional regulation activity of p53/TP53. Monomethylates RB1 at 'Lys-860'., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000993 RNA polymerase II complex binding;GO:0046975 histone H3K36 methyltransferase activity;GO:0016279 protein-lysine N-methyltransferase activity;GO:0140999 histone H3K4 trimethyltransferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0043516 regulation of DNA damage response, signal transduction by p53 class mediator;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0007507 heart development;GO:0008285 negative regulation of cell population proliferation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "C3RZA1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1REY1-1", "uniprot_id": "F1REY1_PIG", "mass": 94418.0, "length": 852, "protein_name": "Lon protease homolog 2, peroxisomal", "gene_name": "LONP2", "organism": "Pig", "refseq_name": "lon protease homolog 2, peroxisomal", "refseq_ac": "XP_005664508", "gene_names_uniprotkb": "LONP2", "gene_names_refseq": "LONP2", "protein_names_uniprotkb": "Lon protease homolog 2, peroxisomal; 3.4.21.-; Lon protease 2; Lon protease-like protein 2; Peroxisomal Lon protease", "protein_names_refseq": "lon protease homolog 2, peroxisomal", "tax_id": 9823, "disease": "", "pathway": " (ssc:100625283); (R-SSC-9033241)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import. May indirectly regulate peroxisomal fatty acid beta-oxidation through degradation of the self-processed forms of TYSND1., [UniProtKB, HAMAP, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0002020 protease binding;GO:0004252 serine-type endopeptidase activity;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0004176 ATP-dependent peptidase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005782 peroxisomal matrix", "go_biological_process": "GO:0016485 protein processing;GO:0006625 protein targeting to peroxisome;GO:0016558 protein import into peroxisome matrix;GO:0006515 protein quality control for misfolded or incompletely synthesized proteins;GO:0031998 regulation of fatty acid beta-oxidation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1REY1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1RFR1-1", "uniprot_id": "F1RFR1_PIG", "mass": 112952.0, "length": 1055, "protein_name": "Serine/threonine-protein kinase", "gene_name": "ULK1", "organism": "Pig", "refseq_name": "serine/threonine-protein kinase ULK1 isoform X1", "refseq_ac": "XP_020928182", "gene_names_uniprotkb": "ULK1", "gene_names_refseq": "ULK1", "protein_names_uniprotkb": "Serine/threonine-protein kinase; 2.7.11.1", "protein_names_refseq": "serine/threonine-protein kinase ULK1 isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100151990); (R-SSC-1632852); (R-SSC-5357905); (R-SSC-8854214); (R-SSC-8876198); (R-SSC-8934903)", "pathway_count": 6, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Serine/threonine-protein kinase involved in autophagy in response to starvation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0042802 identical protein binding;GO:0044877 protein-containing complex binding;GO:0031267 small GTPase binding", "go_cellular_component": "GO:0000421 autophagosome membrane;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005776 autophagosome;GO:0034045 phagophore assembly site membrane", "go_biological_process": "GO:0000045 autophagosome assembly;GO:0007165 signal transduction;GO:0008285 negative regulation of cell population proliferation;GO:0010506 regulation of autophagy;GO:0042594 response to starvation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1RFR1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1RFU7-1", "uniprot_id": "F1RFU7_PIG", "mass": 88007.0, "length": 796, "protein_name": "Cadherin 11", "gene_name": "CDH11", "organism": "Pig", "refseq_name": "cadherin-11 preproprotein", "refseq_ac": "NP_001231411", "gene_names_uniprotkb": "CDH11", "gene_names_refseq": "CDH11", "protein_names_uniprotkb": "Cadherin 11", "protein_names_refseq": "cadherin 11, type 2, OB-cadherin (osteoblast); cadherin-11 preproprotein", "tax_id": 9823, "disease": "", "pathway": " (ssc:100525579); (R-SSC-418990); (R-SSC-9762292); (R-SSC-9958825)", "pathway_count": 4, "publication_count": 2, "publication_id_list": "23162011;32543654", "class_list": "", "function": "Cadherins are calcium-dependent cell adhesion proteins., [UniProtKB, UniProtKB]; Results indicate the necessity of cadherin-11 for dystrophic calcific nodule formation, which proceeds through an Erk1/2-dependent pathway., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A4X1UU14", "ec_number_list": "", "go_molecular_function": "GO:0005509 calcium ion binding;GO:0045296 cadherin binding;GO:0008013 beta-catenin binding", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0005737 cytoplasm;GO:0005912 adherens junction;GO:0016342 catenin complex;GO:0098685 Schaffer collateral - CA1 synapse", "go_biological_process": "GO:0016477 cell migration;GO:0030336 negative regulation of cell migration;GO:0000902 cell morphogenesis;GO:0048041 focal adhesion assembly;GO:0050804 modulation of chemical synaptic transmission", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "F1RFU7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1RFW5-1", "uniprot_id": "F1RFW5_PIG", "mass": 22870.0, "length": 203, "protein_name": "Ras-related protein Rab-13", "gene_name": "RAB13", "organism": "Pig", "refseq_name": "ras-related protein Rab-13", "refseq_ac": "XP_013852534", "gene_names_uniprotkb": "RAB13", "gene_names_refseq": "RAB13", "protein_names_uniprotkb": "Ras-related protein Rab-13; 3.6.5.2", "protein_names_refseq": "ras-related protein Rab-13", "tax_id": 9823, "disease": "", "pathway": " (ssc:100154707); (R-SSC-8876198)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0004862 cAMP-dependent protein kinase inhibitor activity;GO:0003925 G protein activity", "go_cellular_component": "GO:0005768 endosome;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0005923 bicellular tight junction;GO:0030027 lamellipodium", "go_biological_process": "GO:0015031 protein transport;GO:0031175 neuron projection development;GO:0072659 protein localization to plasma membrane;GO:0070830 bicellular tight junction assembly;GO:0006887 exocytosis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1RFW5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1RFX9-1", "uniprot_id": "M2OM_PIG", "mass": 36777.0, "length": 333, "protein_name": "Mitochondrial 2-oxoglutarate/malate carrier protein", "gene_name": "SLC25A11", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "SLC25A11", "gene_names_refseq": "", "protein_names_uniprotkb": "Mitochondrial 2-oxoglutarate/malate carrier protein; Alpha-oxoglutarate carrier; OGCP; SLC25A11; Solute carrier family 25 member 11", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-428643); (R-SSC-9856872)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "4063354", "class_list": "", "function": "Catalyzes the transport of 2-oxoglutarate (alpha-oxoglutarate) across the inner mitochondrial membrane in an electroneutral exchange for malate (PubMed:4063354). Can also exchange 2-oxoglutarate for other dicarboxylic acids such as malonate, succinate, maleate and oxaloacetate, although with lower affinity (PubMed:4063354). Substrate exchange across the membrane occurs consecutively with one substrate being transported first, then dissociating from the substrate binding site before the second substrate binds for transport in the opposite direction (By similarity). Does not transport glutathione (By similarity). In addition can facilitate proton transport in the presence of protonophores such as long-chain fatty acids, contributing to mitochondrial uncoupling and regulation of mitochondrial energetic efficiency (By similarity). Contributes to several metabolic processes, including the malate-aspartate shuttle, the oxoglutarate/isocitrate shuttle, gluconeogenesis from lactate, and nitrogen metabolism (By similarity). Maintains mitochondrial fusion and fission events, and the organization and morphology of cristae (By similarity). Involved in the regulation of apoptosis (By similarity)., [UniProtKB, PubMed, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0015139 alpha-ketoglutarate transmembrane transporter activity;GO:0022857 transmembrane transporter activity;GO:0015297 antiporter activity", "go_cellular_component": "GO:0005743 mitochondrial inner membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1RFX9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1RGT2-1", "uniprot_id": "F1RGT2_PIG", "mass": 45657.0, "length": 426, "protein_name": "hypoxia-inducible factor-proline dioxygenase", "gene_name": "EGLN1", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "EGLN1", "gene_names_refseq": "", "protein_names_uniprotkb": "hypoxia-inducible factor-proline dioxygenase; 1.14.11.29", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-1234176)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0008198 ferrous iron binding;GO:0031418 L-ascorbic acid binding;GO:0031545 peptidyl-proline 4-dioxygenase activity;GO:0160082 hypoxia-inducible factor-proline dioxygenase activity", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0014069 postsynaptic density", "go_biological_process": "GO:1902072 negative regulation of hypoxia-inducible factor-1alpha signaling pathway;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0006879 intracellular iron ion homeostasis;GO:0071456 cellular response to hypoxia;GO:0045765 regulation of angiogenesis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1RGT2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1RHB5-1", "uniprot_id": "F1RHB5_PIG", "mass": 26243.0, "length": 246, "protein_name": "Neurogenin 1", "gene_name": "NEUROG1", "organism": "Pig", "refseq_name": "neurogenin-1", "refseq_ac": "XP_020940439", "gene_names_uniprotkb": "NEUROG1", "gene_names_refseq": "NEUROG1", "protein_names_uniprotkb": "Neurogenin 1", "protein_names_refseq": "neurogenin-1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100511625)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003682 chromatin binding;GO:0042803 protein homodimerization activity;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0070888 E-box binding", "go_cellular_component": "GO:0005634 nucleus;GO:0043204 perikaryon", "go_biological_process": "GO:0030432 peristalsis;GO:0031223 auditory behavior;GO:0048634 regulation of muscle organ development;GO:0071626 mastication;GO:0097094 craniofacial suture morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1RHB5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1RI70-1", "uniprot_id": "F1RI70_PIG", "mass": 46063.0, "length": 417, "protein_name": "P2X purinoceptor", "gene_name": "P2RX2", "organism": "Pig", "refseq_name": "P2X purinoceptor 2 isoform X5", "refseq_ac": "XP_020929608", "gene_names_uniprotkb": "P2RX2", "gene_names_refseq": "P2RX2", "protein_names_uniprotkb": "P2X purinoceptor; P2X purinoceptor 2", "protein_names_refseq": "P2X purinoceptor 2 isoform X5", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-139853); (R-SSC-418346)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "ATP-gated nonselective transmembrane cation channel permeable to potassium, sodium and calcium. Activation by extracellular ATP induces a variety of cellular responses, such as excitatory postsynaptic responses in sensory neurons, neuromuscular junctions (NMJ) formation, hearing, perception of taste and peristalsis. In the inner ear, regulates sound transduction and auditory neurotransmission, outer hair cell electromotility, inner ear gap junctions, and K(+) recycling. Mediates synaptic transmission between neurons and from neurons to smooth muscle., [UniProtKB, UniProtKB, UniProtKB]; Receptor for ATP that acts as a ligand-gated ion channel., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0042802 identical protein binding;GO:0001614 purinergic nucleotide receptor activity;GO:0004931 extracellularly ATP-gated monoatomic cation channel activity", "go_cellular_component": "GO:0098992 neuronal dense core vesicle;GO:0005886 plasma membrane;GO:0043235 receptor complex;GO:0016324 apical plasma membrane;GO:0098794 postsynapse", "go_biological_process": "GO:0007605 sensory perception of sound;GO:0070588 calcium ion transmembrane transport;GO:0033198 response to ATP", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1RI70-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1RIN3-1", "uniprot_id": "F1RIN3_PIG", "mass": 22311.0, "length": 210, "protein_name": "Neurotrophin-4", "gene_name": "NTF4", "organism": "Pig", "refseq_name": "neurotrophin-4 precursor", "refseq_ac": "NP_001230642", "gene_names_uniprotkb": "NTF4", "gene_names_refseq": "NTF4", "protein_names_uniprotkb": "Neurotrophin-4", "protein_names_refseq": "neurotrophin-4 precursor", "tax_id": 9823, "disease": "", "pathway": " (ssc:100511085); (R-SSC-1257604); (R-SSC-6811558); (R-SSC-9026527); (R-SSC-9028731)", "pathway_count": 5, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008083 growth factor activity;GO:0005163 nerve growth factor receptor binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0008021 synaptic vesicle", "go_biological_process": "GO:0007169 cell surface receptor protein tyrosine kinase signaling pathway;GO:0048812 neuron projection morphogenesis;GO:0043524 negative regulation of neuron apoptotic process;GO:0050804 modulation of chemical synaptic transmission;GO:0021675 nerve development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1RIN3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P79290-1", "uniprot_id": "NOS2_PIG", "mass": 131313.0, "length": 1157, "protein_name": "Nitric oxide synthase, inducible", "gene_name": "NOS2", "organism": "Pig", "refseq_name": "nitric oxide synthase, inducible isoform X1", "refseq_ac": "XP_005669136", "gene_names_uniprotkb": "NOS2", "gene_names_refseq": "INOS; NOS2a; NOS2", "protein_names_uniprotkb": "Nitric oxide synthase, inducible; 1.14.13.39; Inducible NO synthase; Inducible NOS; NOS type II; Peptidyl-cysteine S-nitrosylase NOS2; iNOS", "protein_names_refseq": "nitric oxide synthase, inducible isoform X1", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-1222556); (R-SSC-392154); (R-SSC-9033241)", "pathway_count": 3, "publication_count": 2, "publication_id_list": "32543654;9613441", "class_list": "", "function": "Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such PTGS2/COX2. As component of the iNOS-S100A8/9 transnitrosylase complex involved in the selective inflammatory stimulus-dependent S-nitrosylation of GAPDH implicated in regulation of the GAIT complex activity and probably multiple targets including ANXA5, EZR, MSN and VIM. Involved in inflammation, enhances the synthesis of pro-inflammatory mediators such as IL6 and IL8., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A287AUH8;A0A287BRU8", "ec_number_list": "", "go_molecular_function": "GO:0004517 nitric-oxide synthase activity;GO:0034617 tetrahydrobiopterin binding;GO:0005516 calmodulin binding;GO:0042803 protein homodimerization activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005777 peroxisome;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "GO:0006954 inflammatory response;GO:0010629 negative regulation of gene expression;GO:0018119 peptidyl-cysteine S-nitrosylation;GO:0032496 response to lipopolysaccharide;GO:0032755 positive regulation of interleukin-6 production", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "P79290-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1RJ89-1", "uniprot_id": "F1RJ89_PIG", "mass": 14692.0, "length": 137, "protein_name": "Regulator of cell cycle", "gene_name": "RGCC", "organism": "Pig", "refseq_name": "regulator of cell cycle RGCC", "refseq_ac": "NP_001231156", "gene_names_uniprotkb": "RGCC", "gene_names_refseq": "RGC32; RGCC", "protein_names_uniprotkb": "Regulator of cell cycle", "protein_names_refseq": "regulator of cell cycle RGCC; response gene to complement 32 protein", "tax_id": 9823, "disease": "", "pathway": " (ssc:100625944)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0019901 protein kinase binding;GO:0030295 protein kinase activator activity;GO:0070412 R-SMAD binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0005813 centrosome", "go_biological_process": "GO:0002430 complement receptor mediated signaling pathway;GO:0010628 positive regulation of gene expression;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0007179 transforming growth factor beta receptor signaling pathway;GO:0071456 cellular response to hypoxia", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1RJ89-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1RKE0-1", "uniprot_id": "F1RKE0_PIG", "mass": 46213.0, "length": 421, "protein_name": "Zona pellucida sperm-binding protein 3", "gene_name": "ZP3", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "ZP3", "gene_names_refseq": "", "protein_names_uniprotkb": "Zona pellucida sperm-binding protein 3", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-2534343)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "10091584;11114588;32543654", "class_list": "", "function": "Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP3 is essential for sperm binding and zona matrix formation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 3, "mined_n_glycosites": 3, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 3, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0035804 structural constituent of egg coat;GO:0032190 acrosin binding;GO:0048018 receptor ligand activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005886 plasma membrane;GO:0035805 egg coat", "go_biological_process": "GO:2000344 positive regulation of acrosome reaction;GO:2000386 positive regulation of ovarian follicle development;GO:0035803 egg coat formation;GO:0007339 binding of sperm to zona pellucida;GO:0002455 humoral immune response mediated by circulating immunoglobulin", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "F1RKE0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1RKS3-1", "uniprot_id": "F1RKS3_PIG", "mass": 42403.0, "length": 380, "protein_name": "Flap endonuclease 1", "gene_name": "FEN1", "organism": "Pig", "refseq_name": "flap endonuclease 1", "refseq_ac": "XP_003122675", "gene_names_uniprotkb": "FEN1", "gene_names_refseq": "FEN1", "protein_names_uniprotkb": "Flap endonuclease 1; 3.1.-.-; FEN-1; Flap structure-specific endonuclease 1", "protein_names_refseq": "flap endonuclease 1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100517749); (R-SSC-110362); (R-SSC-174437); (R-SSC-5651801); (R-SSC-5685939); (R-SSC-69166)", "pathway_count": 6, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap. Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity. Also involved in replication and repair of rDNA and in repairing mitochondrial DNA., [UniProtKB, UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0003677 DNA binding;GO:0030145 manganese ion binding;GO:0004523 RNA-DNA hybrid ribonuclease activity;GO:0008409 5'-3' exonuclease activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005739 mitochondrion;GO:0032991 protein-containing complex", "go_biological_process": "GO:0006284 base-excision repair;GO:0043137 DNA replication, removal of RNA primer;GO:0045876 positive regulation of sister chromatid cohesion", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1RKS3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1RL74-1", "uniprot_id": "F1RL74_PIG", "mass": 55347.0, "length": 489, "protein_name": "calcium/calmodulin-dependent protein kinase", "gene_name": "CAMK2A", "organism": "Pig", "refseq_name": "calcium/calmodulin dependent protein kinase II alpha isoform 1", "refseq_ac": "XP_005653019", "gene_names_uniprotkb": "CAMK2A", "gene_names_refseq": "CAMK2A", "protein_names_uniprotkb": "calcium/calmodulin-dependent protein kinase; 2.7.11.17", "protein_names_refseq": "calcium/calmodulin dependent protein kinase II alpha isoform 1; calcium/calmodulin-dependent protein kinase type II subunit alpha", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005516 calmodulin binding;GO:0005524 ATP binding;GO:0042803 protein homodimerization activity;GO:0004683 calcium/calmodulin-dependent protein kinase activity", "go_cellular_component": "GO:0043197 dendritic spine;GO:0033017 sarcoplasmic reticulum membrane;GO:0005954 calcium- and calmodulin-dependent protein kinase complex", "go_biological_process": "GO:0043123 positive regulation of canonical NF-kappaB signal transduction;GO:0060996 dendritic spine development;GO:0038166 angiotensin-activated signaling pathway;GO:0046427 positive regulation of receptor signaling pathway via JAK-STAT;GO:0071346 cellular response to type II interferon", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1RL74-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1RL88-1", "uniprot_id": "F1RL88_PIG", "mass": 80360.0, "length": 739, "protein_name": "Sulfate transporter", "gene_name": "SLC26A2", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "SLC26A2", "gene_names_refseq": "", "protein_names_uniprotkb": "Sulfate transporter; Solute carrier family 26 member 2", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-174362); (R-SSC-427601)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Sulfate transporter which mediates sulfate uptake into chondrocytes in order to maintain adequate sulfation of proteoglycans which is needed for cartilage development. Mediates electroneutral anion exchange of sulfate ions for oxalate ions, sulfate and oxalate ions for chloride and/or hydroxyl ions and chloride ions for bromide, iodide and nitrate ions. The coupling of sulfate transport to both hydroxyl and chloride ions likely serves to ensure transport at both acidic pH when most sulfate uptake is mediated by sulfate-hydroxide exchange and alkaline pH when most sulfate uptake is mediated by sulfate-chloride exchange. Essential for chondrocyte proliferation, differentiation and cell size expansion., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0019531 oxalate transmembrane transporter activity;GO:0008271 secondary active sulfate transmembrane transporter activity;GO:0015116 sulfate transmembrane transporter activity;GO:0140900 chloride:bicarbonate antiporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016324 apical plasma membrane", "go_biological_process": "GO:1902476 chloride transmembrane transport;GO:0002062 chondrocyte differentiation;GO:0035988 chondrocyte proliferation;GO:1902358 sulfate transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1RL88-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1RLS0-1", "uniprot_id": "F1RLS0_PIG", "mass": 45205.0, "length": 414, "protein_name": "Adenosine receptor A2", "gene_name": "ADORA2A", "organism": "Pig", "refseq_name": "adenosine A2a receptor", "refseq_ac": "XP_003483510", "gene_names_uniprotkb": "ADORA2A", "gene_names_refseq": "ADORA2A", "protein_names_uniprotkb": "Adenosine receptor A2", "protein_names_refseq": "A2a adenosine receptor; adenosine A2a receptor", "tax_id": 9823, "disease": "", "pathway": " (ssc:503661); (R-SSC-417973); (R-SSC-5683826)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8D1XY94", "ec_number_list": "", "go_molecular_function": "GO:0005516 calmodulin binding;GO:0019899 enzyme binding;GO:0042802 identical protein binding;GO:0001609 G protein-coupled adenosine receptor activity;GO:0008289 lipid binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0045202 synapse", "go_biological_process": "GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0014074 response to purine-containing compound;GO:0001963 synaptic transmission, dopaminergic;GO:0001973 G protein-coupled adenosine receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1RLS0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1RM07-1", "uniprot_id": "F1RM07_PIG", "mass": 170424.0, "length": 1500, "protein_name": "Rho GTPase-activating protein 35", "gene_name": "ARHGAP35", "organism": "Pig", "refseq_name": "rho GTPase-activating protein 35", "refseq_ac": "XP_020950281", "gene_names_uniprotkb": "ARHGAP35", "gene_names_refseq": "ARHGAP35", "protein_names_uniprotkb": "Rho GTPase-activating protein 35; Glucocorticoid receptor DNA-binding factor 1", "protein_names_refseq": "rho GTPase-activating protein 35", "tax_id": 9823, "disease": "", "pathway": " (ssc:100514580); (R-SSC-416550); (R-SSC-8849471); (R-SSC-8980692); (R-SSC-9013026); (R-SSC-9013106); (R-SSC-9013148); (R-SSC-9013149); (R-SSC-9013404); (R-SSC-9013406); (R-SSC-9013408); (R-SSC-9013409); (R-SSC-9013423); (R-SSC-9696264); (R-SSC-9696270); (R-SSC-9696273)", "pathway_count": 16, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "A0A4X1W347;K9J4Q7", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0003924 GTPase activity;GO:0005096 GTPase activator activity;GO:0005525 GTP binding;GO:0005543 phospholipid binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0015629 actin cytoskeleton;GO:0036064 ciliary basal body", "go_biological_process": "GO:0050770 regulation of axonogenesis;GO:0008064 regulation of actin polymerization or depolymerization;GO:0006351 DNA-templated transcription;GO:0010976 positive regulation of neuron projection development;GO:0051056 regulation of small GTPase mediated signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1RM07-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1RMN6-1", "uniprot_id": "F1RMN6_PIG", "mass": 69594.0, "length": 624, "protein_name": "Sphingomyelin phosphodiesterase", "gene_name": "SMPD1", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "SMPD1", "gene_names_refseq": "", "protein_names_uniprotkb": "Sphingomyelin phosphodiesterase; 3.1.4.12", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-9769739); (R-SSC-9840310)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Converts sphingomyelin to ceramide. Exists as two enzymatic forms that arise from alternative trafficking of a single protein precursor, one that is targeted to the endolysosomal compartment, whereas the other is released extracellularly. However, in response to various forms of stress, lysosomal exocytosis may represent a major source of the secretory form., [UniProtKB, UniProtKB]; In the lysosomes, converts sphingomyelin to ceramide. Plays an important role in the export of cholesterol from the intraendolysosomal membranes. Also has phospholipase C activities toward 1,2-diacylglycerolphosphocholine and 1,2-diacylglycerolphosphoglycerol. Modulates stress-induced apoptosis through the production of ceramide., [UniProtKB, UniProtKB]; This form is generated following cleavage by CASP7 in the extracellular milieu in response to bacterial infection. It shows increased ability to convert sphingomyelin to ceramide and promotes plasma membrane repair. Plasma membrane repair by ceramide counteracts the action of gasdermin-D (GSDMD) perforin (PRF1) pores that are formed in response to bacterial infection., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0016798 hydrolase activity, acting on glycosyl bonds;GO:0061750 acid sphingomyelin phosphodiesterase activity;GO:0034480 phosphatidylcholine phospholipase C activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005811 lipid droplet;GO:0005886 plasma membrane;GO:0005764 lysosome;GO:0036019 endolysosome", "go_biological_process": "GO:0001778 plasma membrane repair;GO:0034612 response to tumor necrosis factor;GO:0043065 positive regulation of apoptotic process;GO:0046513 ceramide biosynthetic process;GO:0071277 cellular response to calcium ion", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1RMN6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1RMU2-1", "uniprot_id": "F1RMU2_PIG", "mass": 40245.0, "length": 349, "protein_name": "Transcription initiation factor TFIID subunit 7", "gene_name": "TAF7", "organism": "Pig", "refseq_name": "transcription initiation factor TFIID subunit 7", "refseq_ac": "XP_005661821", "gene_names_uniprotkb": "TAF7", "gene_names_refseq": "TAF7", "protein_names_uniprotkb": "Transcription initiation factor TFIID subunit 7", "protein_names_refseq": "transcription initiation factor TFIID subunit 7", "tax_id": 9823, "disease": "", "pathway": " (ssc:100523236); (R-SSC-674695); (R-SSC-6804756); (R-SSC-73776); (R-SSC-73779); (R-SSC-75953); (R-SSC-76042)", "pathway_count": 7, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "The TFIID basal transcription factor complex plays a major role in the initiation of RNA polymerase II (Pol II)-dependent transcription. TFIID recognizes and binds promoters with or without a TATA box via its subunit TBP, a TATA-box-binding protein, and promotes assembly of the pre-initiation complex (PIC). The TFIID complex consists of TBP and TBP-associated factors (TAFs), including TAF1, TAF2, TAF3, TAF4, TAF5, TAF6, TAF7, TAF8, TAF9, TAF10, TAF11, TAF12 and TAF13. TAF7 forms a promoter DNA binding subcomplex of TFIID, together with TAF1 and TAF2. Part of a TFIID complex containing TAF10 (TFIID alpha) and a TFIID complex lacking TAF10 (TFIID beta)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A4X1SLT6", "ec_number_list": "", "go_molecular_function": "GO:0046982 protein heterodimerization activity;GO:0000976 transcription cis-regulatory region binding;GO:0003743 translation initiation factor activity;GO:0046966 nuclear thyroid hormone receptor binding;GO:0061628 histone H3K27me3 reader activity", "go_cellular_component": "GO:0033276 transcription factor TFTC complex;GO:0005737 cytoplasm;GO:0071339 MLL1 complex;GO:0005669 transcription factor TFIID complex", "go_biological_process": "GO:0060261 positive regulation of transcription initiation by RNA polymerase II;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006357 regulation of transcription by RNA polymerase II;GO:0042789 mRNA transcription by RNA polymerase II;GO:0045347 negative regulation of MHC class II biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1RMU2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1RN44-1", "uniprot_id": "F1RN44_PIG", "mass": 43932.0, "length": 413, "protein_name": "Lysosome-associated membrane glycoprotein 1", "gene_name": "LAMP1", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "LAMP1", "gene_names_refseq": "", "protein_names_uniprotkb": "Lysosome-associated membrane glycoprotein 1; CD107 antigen-like family member A", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-6798695)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 5, "predicted_n_glycosites": 0, "predicted_o_glycosites": 5, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0019899 enzyme binding;GO:0019904 protein domain specific binding;GO:0008200 ion channel inhibitor activity", "go_cellular_component": "GO:0000421 autophagosome membrane;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0048471 perinuclear region of cytoplasm;GO:0005765 lysosomal membrane", "go_biological_process": "GO:0072594 establishment of protein localization to organelle;GO:0050821 protein stabilization;GO:0090160 Golgi to lysosome transport;GO:0043323 positive regulation of natural killer cell degranulation;GO:0007042 lysosomal lumen acidification", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1RN44-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1RN87-1", "uniprot_id": "F1RN87_PIG", "mass": 84238.0, "length": 761, "protein_name": "GIT ArfGAP 1", "gene_name": "GIT1", "organism": "Pig", "refseq_name": "ARF GTPase-activating protein GIT1 isoform X1", "refseq_ac": "XP_020923174", "gene_names_uniprotkb": "GIT1", "gene_names_refseq": "GIT1", "protein_names_uniprotkb": "GIT ArfGAP 1", "protein_names_refseq": "ARF GTPase-activating protein GIT1 isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100520151); (R-SSC-3928664); (R-SSC-9013148); (R-SSC-9013149); (R-SSC-9013404); (R-SSC-9013406); (R-SSC-9013420); (R-SSC-9013423); (R-SSC-9013424)", "pathway_count": 9, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005096 GTPase activator activity;GO:0008270 zinc ion binding;GO:0044877 protein-containing complex binding;GO:0031267 small GTPase binding;GO:0043015 gamma-tubulin binding", "go_cellular_component": "GO:0044305 calyx of Held;GO:0005813 centrosome;GO:0005829 cytosol;GO:0005925 focal adhesion;GO:0045202 synapse", "go_biological_process": "GO:0007626 locomotory behavior;GO:0032691 negative regulation of interleukin-1 beta production;GO:0071222 cellular response to lipopolysaccharide;GO:0007420 brain development;GO:0061743 motor learning", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1RN87-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1RNH0-1", "uniprot_id": "F1RNH0_PIG", "mass": 52581.0, "length": 472, "protein_name": "Leukocyte receptor cluster member 4", "gene_name": "MBOAT7", "organism": "Pig", "refseq_name": "lysophospholipid acyltransferase 7 isoform X1", "refseq_ac": "XP_003127465", "gene_names_uniprotkb": "MBOAT7", "gene_names_refseq": "MBOAT7", "protein_names_uniprotkb": "Leukocyte receptor cluster member 4; Lysophospholipid acyltransferase 7; Membrane-bound O-acyltransferase domain-containing protein 7", "protein_names_refseq": "lysophospholipid acyltransferase 7 isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100521498); (R-SSC-1482922)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0071617 lysophospholipid acyltransferase activity;GO:0008374 O-acyltransferase activity", "go_cellular_component": "GO:0016020 membrane;GO:0005789 endoplasmic reticulum membrane;GO:0044233 mitochondria-associated endoplasmic reticulum membrane contact site", "go_biological_process": "GO:0036151 phosphatidylcholine acyl-chain remodeling;GO:0006661 phosphatidylinositol biosynthetic process;GO:0090207 regulation of triglyceride metabolic process;GO:0030258 lipid modification;GO:0036149 phosphatidylinositol acyl-chain remodeling", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1RNH0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1RPV4-1", "uniprot_id": "F1RPV4_PIG", "mass": 12051.0, "length": 110, "protein_name": "Chemokine (C motif) ligand 1", "gene_name": "XCL1", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "XCL1", "gene_names_refseq": "", "protein_names_uniprotkb": "Chemokine (C motif) ligand 1", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-380108); (R-SSC-416476)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A4X1V3U1", "ec_number_list": "", "go_molecular_function": "GO:0008009 chemokine activity;GO:0048020 CCR chemokine receptor binding", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0006954 inflammatory response;GO:0010820 positive regulation of T cell chemotaxis;GO:0030335 positive regulation of cell migration;GO:0061844 antimicrobial humoral immune response mediated by antimicrobial peptide;GO:0070098 chemokine-mediated signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1RPV4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1RPX0-1", "uniprot_id": "F1RPX0_PIG", "mass": 93662.0, "length": 871, "protein_name": "Speckle targeted PIP5K1A-regulated poly(A) polymerase", "gene_name": "TUT1", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "TUT1", "gene_names_refseq": "", "protein_names_uniprotkb": "Speckle targeted PIP5K1A-regulated poly(A) polymerase; 2.7.7.19; 2.7.7.52; RNA-binding motif protein 21; U6 snRNA-specific terminal uridylyltransferase 1", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-9770562)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Poly(A) polymerase that creates the 3'-poly(A) tail of specific pre-mRNAs. Localizes to nuclear speckles together with PIP5K1A and mediates polyadenylation of a select set of mRNAs, such as HMOX1. In addition to polyadenylation, it is also required for the 3'-end cleavage of pre-mRNAs: binds to the 3'UTR of targeted pre-mRNAs and promotes the recruitment and assembly of the CPSF complex on the 3'UTR of pre-mRNAs. In addition to adenylyltransferase activity, also has uridylyltransferase activity. However, the ATP ratio is higher than UTP in cells, suggesting that it functions primarily as a poly(A) polymerase. Acts as a specific terminal uridylyltransferase for U6 snRNA in vitro: responsible for a controlled elongation reaction that results in the restoration of the four 3'-terminal UMP-residues found in newly transcribed U6 snRNA. Not involved in replication-dependent histone mRNA degradation., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0008270 zinc ion binding;GO:0019899 enzyme binding;GO:0003730 mRNA 3'-UTR binding;GO:0050265 RNA uridylyltransferase activity", "go_cellular_component": "GO:0005730 nucleolus;GO:0016607 nuclear speck;GO:0005847 mRNA cleavage and polyadenylation specificity factor complex", "go_biological_process": "GO:0051252 regulation of RNA metabolic process;GO:0034477 U6 snRNA 3'-end processing;GO:0031123 RNA 3'-end processing;GO:0180010 co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1RPX0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1RQW9-1", "uniprot_id": "F1RQW9_PIG", "mass": 135258.0, "length": 1233, "protein_name": "[histone H3]-lysine(9) N-methyltransferase", "gene_name": "EHMT2", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "EHMT2", "gene_names_refseq": "", "protein_names_uniprotkb": "[histone H3]-lysine(9) N-methyltransferase; 2.1.1.367", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-2559582); (R-SSC-3214841); (R-SSC-6804760); (R-SSC-73762); (R-SSC-8953750)", "pathway_count": 5, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0002039 p53 binding;GO:1990841 promoter-specific chromatin binding;GO:0046974 histone H3K9 methyltransferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0016607 nuclear speck;GO:0000785 chromatin;GO:0005654 nucleoplasm;GO:0005694 chromosome", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006275 regulation of DNA replication;GO:0030261 chromosome condensation;GO:0032259 methylation;GO:0040029 epigenetic regulation of gene expression", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1RQW9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1RR64-1", "uniprot_id": "F1RR64_PIG", "mass": 32665.0, "length": 299, "protein_name": "Endonuclease", "gene_name": "ENDOG", "organism": "Pig", "refseq_name": "endonuclease G, mitochondrial", "refseq_ac": "XP_003122256", "gene_names_uniprotkb": "ENDOG", "gene_names_refseq": "ENDOG", "protein_names_uniprotkb": "Endonuclease; 3.1.30.-", "protein_names_refseq": "endonuclease G, mitochondrial", "tax_id": 9823, "disease": "", "pathway": " (ssc:100514888)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0042803 protein homodimerization activity;GO:0003676 nucleic acid binding;GO:0004521 RNA endonuclease activity;GO:0000014 single-stranded DNA endodeoxyribonuclease activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0090297 positive regulation of mitochondrial DNA replication;GO:0006974 DNA damage response;GO:0010508 positive regulation of autophagy;GO:0032007 negative regulation of TOR signaling;GO:0006309 apoptotic DNA fragmentation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1RR64-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1RR71-1", "uniprot_id": "F1RR71_PIG", "mass": 51708.0, "length": 455, "protein_name": "Gamma-aminobutyric acid receptor subunit alpha-1", "gene_name": "GABRA1", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "GABRA1", "gene_names_refseq": "", "protein_names_uniprotkb": "Gamma-aminobutyric acid receptor subunit alpha-1; GABA(A) receptor subunit alpha-1", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-977443)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A5K1V3P2;I3LPL5", "ec_number_list": "", "go_molecular_function": "GO:0004890 GABA-A receptor activity;GO:0022851 GABA-gated chloride ion channel activity;GO:1904315 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential", "go_cellular_component": "GO:0098982 GABA-ergic synapse;GO:0043197 dendritic spine;GO:0045211 postsynaptic membrane;GO:0098794 postsynapse;GO:0034707 chloride channel complex", "go_biological_process": "GO:0007214 gamma-aminobutyric acid signaling pathway;GO:1902476 chloride transmembrane transport;GO:0051932 synaptic transmission, GABAergic;GO:1904862 inhibitory synapse assembly", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1RR71-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1RR72-1", "uniprot_id": "F1RR72_PIG", "mass": 55204.0, "length": 475, "protein_name": "Gamma-aminobutyric acid receptor subunit gamma-2", "gene_name": "GABRG2", "organism": "Pig", "refseq_name": "gamma-aminobutyric acid receptor subunit gamma-2 isoform X1", "refseq_ac": "XP_003134135", "gene_names_uniprotkb": "GABRG2", "gene_names_refseq": "GABRG2", "protein_names_uniprotkb": "Gamma-aminobutyric acid receptor subunit gamma-2; GABA(A) receptor subunit gamma-2", "protein_names_refseq": "gamma-aminobutyric acid receptor subunit gamma-2 isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100516405); (R-SSC-977443)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A4X1TY82", "ec_number_list": "", "go_molecular_function": "GO:0004890 GABA-A receptor activity;GO:0022851 GABA-gated chloride ion channel activity;GO:1904315 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential", "go_cellular_component": "GO:0098982 GABA-ergic synapse;GO:0030424 axon;GO:0045211 postsynaptic membrane;GO:0034707 chloride channel complex;GO:1902711 GABA-A receptor complex", "go_biological_process": "GO:0007214 gamma-aminobutyric acid signaling pathway;GO:0071420 cellular response to histamine;GO:1904862 inhibitory synapse assembly;GO:1902476 chloride transmembrane transport;GO:0051932 synaptic transmission, GABAergic", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1RR72-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SAM7-1", "uniprot_id": "AMNLS_PIG", "mass": 55186.0, "length": 519, "protein_name": "Protein amnionless", "gene_name": "AMN", "organism": "Pig", "refseq_name": "protein amnionless isoform 1 precursor", "refseq_ac": "XP_020937290", "gene_names_uniprotkb": "AMN", "gene_names_refseq": "AMN", "protein_names_uniprotkb": "Protein amnionless", "protein_names_refseq": "protein amnionless isoform 1 precursor; protein amnionless", "tax_id": 9823, "disease": "", "pathway": " (ssc:100157003)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "30523278", "class_list": "", "function": "Membrane-bound component of the endocytic receptor formed by AMN and CUBN (PubMed:30523278). Required for normal CUBN glycosylation and trafficking to the cell surface. The complex formed by AMN and CUBN is required for efficient absorption of vitamin B12. Required for normal CUBN-mediated protein transport in the kidney (By similarity)., [UniProtKB, UniProtKB, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0038024 cargo receptor activity", "go_cellular_component": "GO:0005905 clathrin-coated pit;GO:0043235 receptor complex;GO:0016324 apical plasma membrane;GO:0010008 endosome membrane;GO:0030139 endocytic vesicle", "go_biological_process": "GO:0097017 renal protein absorption;GO:0015031 protein transport;GO:0006898 receptor-mediated endocytosis;GO:0008104 intracellular protein localization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SAM7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "O11780-1", "uniprot_id": "BGH3_PIG", "mass": 74462.0, "length": 683, "protein_name": "Transforming growth factor-beta-induced protein ig-h3", "gene_name": "TGFBI", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "TGFBI", "gene_names_refseq": "", "protein_names_uniprotkb": "Transforming growth factor-beta-induced protein ig-h3; Beta ig-h3; Kerato-epithelin; RGD-CAP; RGD-containing collagen-associated protein", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "9061001", "class_list": "", "function": "Plays a role in cell adhesion (By similarity). May play a role in cell-collagen interactions (PubMed:9061001)., [UniProtKB, PubMed, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0050839 cell adhesion molecule binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0031012 extracellular matrix", "go_biological_process": "GO:0007155 cell adhesion;GO:0030198 extracellular matrix organization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "O11780-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P01168-1", "uniprot_id": "SMS_PIG", "mass": 12689.0, "length": 116, "protein_name": "Somatostatin", "gene_name": "SST", "organism": "Pig", "refseq_name": "somatostatin precursor", "refseq_ac": "NP_001009583", "gene_names_uniprotkb": "SST", "gene_names_refseq": "SRIF; SST", "protein_names_uniprotkb": "Somatostatin", "protein_names_refseq": "somatostatin precursor", "tax_id": 9823, "disease": "", "pathway": " (ssc:494469); (R-SSC-375276); (R-SSC-418594)", "pathway_count": 3, "publication_count": 7, "publication_id_list": "1252409;18753129;2567292;2865169;34314850;6107906;7353633", "class_list": "", "function": "Demonstrate diverse neuronal, neuroendocrine, and cardiovascular actions of a somatostatin gene-encoded hormone, [RefSeq, PubMed]; Inhibits the secretion of pituitary hormones, including that of growth hormone/somatotropin (GH1), PRL, ACTH, luteinizing hormone (LH) and TSH. Also impairs ghrelin- and GnRH-stimulated secretion of GH1 and LH; the inhibition of ghrelin-stimulated secretion of GH1 can be further increased by neuronostatin., [UniProtKB, UniProtKB]; May enhance low-glucose-induced glucagon release by pancreatic alpha cells. This effect may be mediated by binding to GPR107 and PKA activation (By similarity). May regulate cardiac contractile function (By similarity). May compromise cardiomyocyte viability. In the central nervous system, may impair memory retention and may affect hippocampal excitability. May also have anxiolytic and anorexigenic effects. May play a role in arterial pressure regulation (By similarity). May inhibit basal, but not ghrelin- or GnRH-stimulated secretion of GH1 or LH, but does not affect the release of other pituitary hormones, including PRL, ACTH, FSH or TSH. Potentiates inhibitory action of somatostatin on ghrelin-stimulated secretion of GH1, but not that on GnRH-stimulated secretion of LH (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Somatostatin immunoreactivity within the urinary bladder nerve fibers and paracervical ganglion urinary bladder projecting neurons in the female pig., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q6PLR2", "ec_number_list": "", "go_molecular_function": "GO:0005179 hormone activity", "go_cellular_component": "GO:0098982 GABA-ergic synapse;GO:0005615 extracellular space;GO:0005829 cytosol", "go_biological_process": "GO:0030334 regulation of cell migration;GO:0099072 regulation of postsynaptic membrane neurotransmitter receptor levels;GO:0038170 somatostatin signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P01168-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P07480-1", "uniprot_id": "GALA_PIG", "mass": 13081.0, "length": 123, "protein_name": "Galanin peptides", "gene_name": "GAL", "organism": "Pig", "refseq_name": "galanin peptides preproprotein", "refseq_ac": "NP_999399", "gene_names_uniprotkb": "GAL; GALN", "gene_names_refseq": "GALN; GAL", "protein_names_uniprotkb": "Galanin peptides", "protein_names_refseq": "galanin peptides preproprotein; galanin peptides; galanin prepropeptide", "tax_id": 9823, "disease": "", "pathway": " (ssc:397465)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "1381832;1718731;22252756;2428032;27175780;34203944;6197320", "class_list": "", "function": "Endocrine hormone of the central and peripheral nervous systems that binds and activates the G protein-coupled receptors GALR1, GALR2, and GALR3. This small neuropeptide may regulate diverse physiologic functions including contraction of smooth muscle of the gastrointestinal and genitourinary tract, growth hormone and insulin release and adrenal secretion., [UniProtKB, PubMed, PubMed]; Localization of galanin, in the nerve fibers of porcine cystic ovaries, [RefSeq, PubMed]; Real-Time PCR revealed the increased expression of mRNA encoding Gal and GalR1 receptor in the pyloric wall tissue of the experimental animals, while the expression(s) of GalR2 and GalR3 were not significantly changed. Publication Status: Online-Only, [RefSeq, PubMed]; Regulatory Influence of Galanin and GALR1/GALR2 Receptors on Inflamed Uterus Contractility in Pigs. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9TRN1", "ec_number_list": "", "go_molecular_function": "GO:0005184 neuropeptide hormone activity;GO:0031763 galanin receptor binding;GO:0004966 galanin receptor activity;GO:0031764 type 1 galanin receptor binding;GO:0031765 type 2 galanin receptor binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0030141 secretory granule", "go_biological_process": "GO:0007218 neuropeptide signaling pathway;GO:0045944 positive regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P07480-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P08132-1", "uniprot_id": "ANXA4_PIG", "mass": 35829.0, "length": 319, "protein_name": "Annexin A4", "gene_name": "ANXA4", "organism": "Pig", "refseq_name": "annexin A4", "refseq_ac": "NP_001161111", "gene_names_uniprotkb": "ANXA4; ANX4", "gene_names_refseq": "ANX4; ANXA4; Annexin-4; P32.5; PAP-II; PP4-X", "protein_names_uniprotkb": "Annexin A4; 35-beta calcimedin; Annexin IV; Annexin-4; Chromobindin-4; Endonexin I; Lipocortin IV; P32.5; PAP-II; PP4-X; Placental anticoagulant protein II; Protein II", "protein_names_refseq": "35-beta calcimedin; Annexin IV; Chromobindin-4; Endonexin I; Lipocortin IV; Placental anticoagulant protein II; Protein II; annexin A4", "tax_id": 9823, "disease": "", "pathway": " (ssc:100312960)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "2956093;8672129", "class_list": "", "function": "Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q29306", "ec_number_list": "", "go_molecular_function": "GO:0005509 calcium ion binding;GO:0005544 calcium-dependent phospholipid binding;GO:0001786 phosphatidylserine binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0012506 vesicle membrane;GO:0042589 zymogen granule membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "P08132-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P09558-1", "uniprot_id": "EDN1_PIG", "mass": 23259.0, "length": 203, "protein_name": "Endothelin-1", "gene_name": "EDN1", "organism": "Pig", "refseq_name": "endothelin-1 preproprotein", "refseq_ac": "NP_999047", "gene_names_uniprotkb": "EDN1", "gene_names_refseq": "EDN1; EDN; ET-1; ET1; PPET1", "protein_names_uniprotkb": "Endothelin-1; ET-1; PPET1; Preproendothelin-1", "protein_names_refseq": "endothelin-1 preproprotein; preproendothelin-1", "tax_id": 9823, "disease": "", "pathway": " (ssc:396915)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "2205205;23717659;2451132;24611481;25380860;26211713;2665739;2669747;27443965", "class_list": "", "function": "ET-1 contributes to formation of oedema during experimental sepsis by a novel mechanism involving increased HBP release from neutrophils., [RefSeq, PubMed]; ET1 was lowest in kidneys removed from live pigs, greater in kidneys from pigs with brain death, and greatest in kidneys from pigs with cardiac arrest., [RefSeq, PubMed]; Endothelin-1 expression is upregulated following therapeutic hypothermia after cardiac arrest. Publication Status: Online-Only, [RefSeq, PubMed]; Endothelins are endothelium-derived vasoconstrictor peptides (PubMed:2451132). Probable ligand for G protein-coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Also binds the DEAR/FBXW7-AS1 receptor (By similarity). Promotes mesenteric arterial wall remodeling via activation of ROCK signaling and subsequent colocalization of NFATC3 with F-actin filaments (By similarity). NFATC3 then translocates to the nucleus where it subsequently promotes the transcription of the smooth muscle hypertrophy and differentiation marker ACTA2 (By similarity)., [UniProtKB, UniProtKB, PubMed, UniProtKB]; In conclusion, endothelial vWF knockdown prevented angiotensin II-induced ET-1 upregulation through attenuation of NOX-mediated O2- production. Publication Status: Online-Only, [RefSeq, PubMed]; Sub-vasomotor concentration of ET-1 leads to vascular dysfunction by impairing endothelium-dependent NO-mediated dilation via p38 kinase-mediated production of superoxide from NADPH oxidase following ETA receptor activation, [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005179 hormone activity;GO:0031707 endothelin A receptor binding;GO:0031708 endothelin B receptor binding", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0086100 endothelin receptor signaling pathway;GO:0045987 positive regulation of smooth muscle contraction;GO:0006874 intracellular calcium ion homeostasis;GO:0019229 regulation of vasoconstriction;GO:1900182 positive regulation of protein localization to nucleus", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P09558-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P10289-1", "uniprot_id": "FABP6_PIG", "mass": 14219.0, "length": 128, "protein_name": "Gastrotropin", "gene_name": "FABP6", "organism": "Pig", "refseq_name": "gastrotropin", "refseq_ac": "NP_999380", "gene_names_uniprotkb": "FABP6; ILBP; ILLBP", "gene_names_refseq": "FABP6; GT; ILBP; ILLBP; PIP", "protein_names_uniprotkb": "Gastrotropin; Fatty acid-binding protein 6; GT; ILBP; Ileal lipid-binding protein; PIP; Porcine ileal peptide", "protein_names_refseq": "gastrotropin; ileal lipid-binding protein; porcine ileal peptide", "tax_id": 9823, "disease": "", "pathway": " (ssc:397423)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "10806391;2584215;3049572;8805562", "class_list": "", "function": "Binds to bile acids and is involved in enterohepatic bile acid metabolism. Required for efficient apical to basolateral transport of conjugated bile acids in ileal enterocytes (By similarity). Stimulates gastric acid and pepsinogen secretion., [UniProtKB, PubMed, PubMed, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005504 fatty acid binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0016020 membrane", "go_biological_process": "GO:0015908 fatty acid transport", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P10289-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P10775-1", "uniprot_id": "RINI_PIG", "mass": 49023.0, "length": 456, "protein_name": "Ribonuclease inhibitor", "gene_name": "RNH1", "organism": "Pig", "refseq_name": "ribonuclease inhibitor", "refseq_ac": "XP_020938200", "gene_names_uniprotkb": "RNH1; RI; RNH", "gene_names_refseq": "RI; RNH1; RNH", "protein_names_uniprotkb": "Ribonuclease inhibitor; Ribonuclease/angiogenin inhibitor 1", "protein_names_refseq": "ribonuclease inhibitor", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 4, "publication_id_list": "2271559;3219361;7877692;8264799", "class_list": "", "function": "Ribonuclease inhibitor which inhibits RNASE1, RNASE2 and angiogenin (ANG). May play a role in redox homeostasis (PubMed:2271559, PubMed:3219361). Required to inhibit the cytotoxic tRNA ribonuclease activity of ANG in the cytoplasm in absence of stress (By similarity). Relocates to the nucleus in response to stress, relieving inhibition of ANG in the cytoplasm, and inhibiting the angiogenic activity of ANG in the nucleus (By similarity)., [UniProtKB, PubMed, PubMed, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008428 ribonuclease inhibitor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0030027 lamellipodium", "go_biological_process": "GO:0016477 cell migration;GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation;GO:0045765 regulation of angiogenesis", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P10775-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P15468-1", "uniprot_id": "RNAS4_PIG", "mass": 16863.0, "length": 147, "protein_name": "Ribonuclease 4", "gene_name": "RNASE4", "organism": "Pig", "refseq_name": "ribonuclease 4 precursor", "refseq_ac": "NP_999101", "gene_names_uniprotkb": "RNASE4; RNS4", "gene_names_refseq": "RNASE4; RNS4", "protein_names_uniprotkb": "Ribonuclease 4; 3.1.27.-; RNase 4; Ribonuclease PL3", "protein_names_refseq": "RNase 4; RNase PL3; ribonuclease 4 precursor; ribonuclease 4; ribonuclease PL3", "tax_id": 9823, "disease": "", "pathway": " (ssc:396976)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "2611266;26748441;8019417", "class_list": "", "function": "Cleaves preferentially after uridine bases. Has antimicrobial activity against uropathogenic E.coli (UPEC). Probably contributes to urinary tract sterility., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0016787 hydrolase activity;GO:0003676 nucleic acid binding;GO:0004519 endonuclease activity;GO:0004540 RNA nuclease activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0019731 antibacterial humoral response;GO:0050830 defense response to Gram-positive bacterium", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "P15468-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P19205-1", "uniprot_id": "ACPH_PIG", "mass": 81244.0, "length": 732, "protein_name": "Acylamino-acid-releasing enzyme", "gene_name": "APEH", "organism": "Pig", "refseq_name": "acylamino-acid-releasing enzyme", "refseq_ac": "NP_999088", "gene_names_uniprotkb": "APEH", "gene_names_refseq": "AAP; AARE; APEH; APH", "protein_names_uniprotkb": "Acylamino-acid-releasing enzyme; 3.4.19.1; AARE; APH; Acyl-peptide hydrolase; Acylaminoacyl-peptidase", "protein_names_refseq": "N-acylaminoacyl-peptide hydrolase; N-acylpeptide hydrolase; acyl-peptide hydrolase; acylamino-acid-releasing enzyme; acylaminoacyl peptidase", "tax_id": 9823, "disease": "", "pathway": " (ssc:396961)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "15280010;16511202;2691504;35799812;8576092", "class_list": "", "function": "Aminopeptidase involved in the degradation of N(alpha)-acylated peptides. Displays exopeptidase activity toward N-formyl and N-acetyl peptides with a preference for dipeptide substrates (By similarity). Catalyzes the hydrolysis of the N-terminal peptide bond of an N-acetylated peptide to generate an N-acetylated amino acid and a peptide with a free N-terminus. It preferentially cleaves off Ac-Ala, Ac-Met and Ac-Ser (By similarity). Hydrolyzes N-formylated peptides likely arising from N-terminal proteolytic cleavage of bacterial and mitochondrial proteins. May act sequentially with ACY1 in the degradation of N-acylated peptides: APEH first cleaves N-acylaminoacids from N-acylated peptides, then ACY1 further hydrolyzes the N-acylaminoacid into free aminoacid and a carboxylate (By similarity). Displays endopeptidase activity involved in the degradation of oxidized and glycated proteins (By similarity)., [UniProtKB, UniProtKB, UniProtKB]; Crystallographic analysis of porcine acylaminoacyl peptidase, [RefSeq, PubMed]; His507 is an important residue that is probably involved in the formation of the 3-dimensional structure (acylaminoacyl peptidase), [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9TS46", "ec_number_list": "", "go_molecular_function": "GO:0004252 serine-type endopeptidase activity;GO:0008242 omega peptidase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0006508 proteolysis", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P19205-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P27485-1", "uniprot_id": "RET4_PIG", "mass": 23067.0, "length": 201, "protein_name": "Retinol-binding protein 4", "gene_name": "RBP4", "organism": "Pig", "refseq_name": "retinol-binding protein 4 precursor", "refseq_ac": "NP_999222", "gene_names_uniprotkb": "RBP4", "gene_names_refseq": "RBP4", "protein_names_uniprotkb": "Retinol-binding protein 4; PRBP; Plasma retinol-binding protein; RBP", "protein_names_refseq": "PRBP; Plasma retinol-binding protein; RBP; retinol-binding protein 4 precursor", "tax_id": 9823, "disease": "", "pathway": " (ssc:397124)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "1723146;20576168;2340335;23859018;27824510;31025395;9757135", "class_list": "", "function": "RBP4 has a role in adipogenesis of porcine preadipocytes through the insulin signaling pathways, [RefSeq, PubMed]; Retinol-binding protein that mediates retinol transport in blood plasma. Delivers retinol from the liver stores to the peripheral tissues. Transfers the bound all-trans retinol to STRA6, that then facilitates retinol transport across the cell membrane., [UniProtKB, UniProtKB]; The aim of this work was to study the effects on litter size of variants of the porcine genes RBP4, ESR1 and IGF2, currently used in genetic tests for different purposes. Publication Status: Online-Only, [RefSeq, PubMed]; There were no statistical differences between the BB genotype and the AB genotype of ESR2 locus in regard to the examined traits. However, a noticeable superiority (P < 0.01) of the BB genotype compared to the homozygous AA genotype, adding almost 2 piglets/litter in TNB and NBA trait, was found., [RefSeq, PubMed]; We screened the mutations of RBP-4 gene in 79 sows with follicular cysts and 100 normal sows without cysts. Results showed that +249-63G>C polymorphisms were significantly associated with follicular cysts, and sows with CC genotype in RBP-4 gene had a high risk of developing follicular cysts., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0019841 retinol binding;GO:0016918 retinal binding;GO:0034632 retinol transmembrane transporter activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0034633 retinol transport", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P27485-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P49171-1", "uniprot_id": "RS26_PIG", "mass": 13015.0, "length": 115, "protein_name": "Small ribosomal subunit protein eS26", "gene_name": "RPS26", "organism": "Pig", "refseq_name": "small ribosomal subunit protein eS26", "refseq_ac": "NP_001090950", "gene_names_uniprotkb": "RPS26", "gene_names_refseq": "RPS26", "protein_names_uniprotkb": "Small ribosomal subunit protein eS26; 40S ribosomal protein S26", "protein_names_refseq": "40S ribosomal protein S26; small ribosomal subunit protein eS26", "tax_id": 9823, "disease": "", "pathway": " (ssc:100037997); (R-SSC-156827); (R-SSC-1799339); (R-SSC-72649); (R-SSC-72689); (R-SSC-72695); (R-SSC-72702); (R-SSC-72706); (R-SSC-975956); (R-SSC-975957); (R-SSC-9954714); (R-SSC-9954716)", "pathway_count": 12, "publication_count": 2, "publication_id_list": "24930395;8672129", "class_list": "", "function": "Component of the small ribosomal subunit (PubMed:24930395). The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:24930395)., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A1XQV1", "ec_number_list": "", "go_molecular_function": "GO:0003729 mRNA binding;GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005840 ribosome;GO:0098556 cytoplasmic side of rough endoplasmic reticulum membrane;GO:0022627 cytosolic small ribosomal subunit", "go_biological_process": "GO:0002181 cytoplasmic translation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "P49171-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P50584-1", "uniprot_id": "AP4A_PIG", "mass": 16835.0, "length": 147, "protein_name": "Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical]", "gene_name": "NUDT2", "organism": "Pig", "refseq_name": "bis(5'-nucleosyl)-tetraphosphatase [asymmetrical]", "refseq_ac": "NP_999474", "gene_names_uniprotkb": "NUDT2; APAH1", "gene_names_refseq": "NUDT2", "protein_names_uniprotkb": "Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical]; 3.6.1.17; Ap4A hydrolase; Ap4Aase; Diadenosine 5',5'''-P1,P4-tetraphosphate asymmetrical hydrolase; Diadenosine tetraphosphatase; Nucleoside diphosphate-linked moiety X motif 2; Nudix motif 2", "protein_names_refseq": "ap4A hydrolase; ap4Aase; bis(5'-nucleosyl)-tetraphosphatase [asymmetrical]; bis(5'-nucleosyl)-tetraphosphatase; diadenosine 5',5'''-P1,P4-tetraphosphate asymmetrical hydrolase; diadenosine tetraphosphatase; nucleoside diphosphate-linked moiety X motif 2; nudix motif 2", "tax_id": 9823, "disease": "", "pathway": " (ssc:397577); (R-SSC-3299685)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "9147133", "class_list": "", "function": "Catalyzes the asymmetric hydrolysis of diadenosine 5',5'''-P1,P4-tetraphosphate (Ap4A) to yield AMP and ATP (PubMed:9147133). Exhibits decapping activity towards FAD-capped RNAs and dpCoA-capped RNAs in vitro (By similarity)., [UniProtKB, UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005525 GTP binding;GO:0004081 bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity", "go_cellular_component": "", "go_biological_process": "GO:0006754 ATP biosynthetic process;GO:0006915 apoptotic process;GO:0006167 AMP biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "P50584-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P56471-1", "uniprot_id": "IDH3A_PIG", "mass": 39632.0, "length": 366, "protein_name": "Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial", "gene_name": "IDH3A", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "IDH3A", "gene_names_refseq": "", "protein_names_uniprotkb": "Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial; 1.1.1.41; Isocitric dehydrogenase subunit alpha; NAD(+)-specific ICDH subunit alpha", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (ssc:100157242)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "2252888", "class_list": "", "function": "Catalytic subunit of the enzyme which catalyzes the decarboxylation of isocitrate (ICT) into alpha-ketoglutarate. The heterodimer composed of the alpha (IDH3A) and beta (IDH3B) subunits and the heterodimer composed of the alpha (IDH3A) and gamma (IDH3G) subunits, have considerable basal activity but the full activity of the heterotetramer (containing two subunits of IDH3A, one of IDH3B and one of IDH3G) requires the assembly and cooperative function of both heterodimers., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0051287 NAD binding;GO:0004449 isocitrate dehydrogenase (NAD+) activity", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0006099 tricarboxylic acid cycle;GO:0006102 isocitrate metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "P56471-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P68266-1", "uniprot_id": "GLTP_PIG", "mass": 23922.0, "length": 209, "protein_name": "Glycolipid transfer protein", "gene_name": "GLTP", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "GLTP", "gene_names_refseq": "", "protein_names_uniprotkb": "Glycolipid transfer protein; GLTP", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 2, "publication_id_list": "10671554;2190982", "class_list": "", "function": "Accelerates the intermembrane transfer of various glycolipids. Catalyzes the transfer of various glycosphingolipids between membranes but does not catalyze the transfer of phospholipids. May be involved in the intracellular translocation of glucosylceramides (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "P17403;Q9MYP3", "ec_number_list": "", "go_molecular_function": "GO:0008289 lipid binding;GO:1902387 ceramide 1-phosphate binding;GO:1902388 ceramide 1-phosphate transfer activity;GO:0017089 glycolipid transfer activity;GO:0120013 lipid transfer activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0035627 ceramide transport;GO:0120009 intermembrane lipid transfer", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "P68266-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q03365-1", "uniprot_id": "HNF1B_PIG", "mass": 61528.0, "length": 559, "protein_name": "Hepatocyte nuclear factor 1-beta", "gene_name": "HNF1B", "organism": "Pig", "refseq_name": "hepatocyte nuclear factor 1-beta", "refseq_ac": "NP_999121", "gene_names_uniprotkb": "HNF1B; TCF2", "gene_names_refseq": "HNF1B; TCF2; vHNF-1", "protein_names_uniprotkb": "Hepatocyte nuclear factor 1-beta; FPC-binding protein; FPCB; HNF-1-beta; HNF-1B; TCF-2; Transcription factor 2", "protein_names_refseq": "FPC-binding protein; FPCB; HNF-1-beta; HNF-1B; LF-B3; TCF-2; hepatocyte nuclear factor 1-beta; transcription factor 2, hepatic; variant hepatic nuclear factor 1; variant hepatic nuclear factor", "tax_id": 9823, "disease": "", "pathway": " (ssc:397002)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "8388098", "class_list": "", "function": "Transcription factor that binds to the inverted palindrome 5'-GTTAATNATTAAC-3' (PubMed:8388098). Binds to the FPC element in the cAMP regulatory unit of the PLAU gene (PubMed:8388098). Transcriptional activity is increased by coactivator PCBD1 (By similarity)., [UniProtKB, UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0042803 protein homodimerization activity;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0048806 genitalia development;GO:0001889 liver development;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0001822 kidney development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q03365-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q29011-1", "uniprot_id": "PGCA_PIG", "mass": 252021.0, "length": 2434, "protein_name": "Aggrecan core protein", "gene_name": "ACAN", "organism": "Pig", "refseq_name": "aggrecan core protein isoform X3", "refseq_ac": "XP_020953958", "gene_names_uniprotkb": "ACAN; AGC1", "gene_names_refseq": "ACAN; AGC1", "protein_names_uniprotkb": "Aggrecan core protein; CSPCP; Cartilage-specific proteoglycan core protein", "protein_names_refseq": "aggrecan core protein isoform X3", "tax_id": 9823, "disease": "", "pathway": " (ssc:397255)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "1326552;1417734;32543654;7827755;9550267", "class_list": "", "function": "This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region. May play a regulatory role in the matrix assembly of the cartilage., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 5, "predicted_n_glycosites": 5, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 3, "reported_o_glycosites": 2, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 3, "total_reported_o_glycosites": 2, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 3, "total_o_glycosites": 2, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 10, "binding_glycan_count": 0, "secondary_ac_list": "A0A287B863;O18833;Q7M2W7", "ec_number_list": "", "go_molecular_function": "GO:0046872 metal ion binding;GO:0030246 carbohydrate binding;GO:0005540 hyaluronic acid binding;GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0005615 extracellular space;GO:0045202 synapse;GO:0072534 perineuronal net", "go_biological_process": "GO:0007155 cell adhesion;GO:0007417 central nervous system development;GO:0001501 skeletal system development", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "Q29011-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q29545-1", "uniprot_id": "ICA_PIG", "mass": 77634.0, "length": 704, "protein_name": "Inhibitor of carbonic anhydrase", "gene_name": "INHCA", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "INHCA; ICA", "gene_names_refseq": "", "protein_names_uniprotkb": "Inhibitor of carbonic anhydrase", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (ssc:396845)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "1463741;18712936;9100029", "class_list": "", "function": "Inhibitor for carbonic anhydrase 2 (CA2) (PubMed:1463741, PubMed:18712936). Does not bind iron ions (By similarity)., [UniProtKB, PubMed, UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005615 extracellular space;GO:0005769 early endosome;GO:0005886 plasma membrane;GO:0055037 recycling endosome", "go_biological_process": "GO:0019731 antibacterial humoral response;GO:0006826 iron ion transport;GO:0051241 negative regulation of multicellular organismal process", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q29545-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q6QAT1-1", "uniprot_id": "RS28_PIG", "mass": 7841.0, "length": 69, "protein_name": "Small ribosomal subunit protein eS28", "gene_name": "RPS28", "organism": "Pig", "refseq_name": "small ribosomal subunit protein eS28", "refseq_ac": "NP_001001587", "gene_names_uniprotkb": "RPS28", "gene_names_refseq": "RPS28", "protein_names_uniprotkb": "Small ribosomal subunit protein eS28; 40S ribosomal protein S28", "protein_names_refseq": "40S ribosomal protein S28; small ribosomal subunit protein eS28", "tax_id": 9823, "disease": "", "pathway": " (ssc:414420); (R-SSC-156827); (R-SSC-1799339); (R-SSC-72649); (R-SSC-72689); (R-SSC-72695); (R-SSC-72702); (R-SSC-72706); (R-SSC-975956); (R-SSC-975957); (R-SSC-9954714); (R-SSC-9954716)", "pathway_count": 12, "publication_count": 1, "publication_id_list": "24930395", "class_list": "", "function": "Component of the small ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:24930395). Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (By similarity)., [UniProtKB, UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0045202 synapse;GO:0005840 ribosome;GO:0098556 cytoplasmic side of rough endoplasmic reticulum membrane;GO:0032040 small-subunit processome;GO:0022627 cytosolic small ribosomal subunit", "go_biological_process": "GO:0042254 ribosome biogenesis;GO:0002181 cytoplasmic translation;GO:0042274 ribosomal small subunit biogenesis;GO:0030490 maturation of SSU-rRNA;GO:0000028 ribosomal small subunit assembly", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q6QAT1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q7SIB7-1", "uniprot_id": "PGK1_PIG", "mass": 44559.0, "length": 417, "protein_name": "Phosphoglycerate kinase 1", "gene_name": "PGK1", "organism": "Pig", "refseq_name": "phosphoglycerate kinase 1", "refseq_ac": "NP_001093402", "gene_names_uniprotkb": "PGK1", "gene_names_refseq": "PGK1", "protein_names_uniprotkb": "Phosphoglycerate kinase 1; 2.7.11.1; 2.7.2.3", "protein_names_refseq": "X-linked phosphoglycerate kinase 1; phosphoglycerate kinase 1", "tax_id": 9823, "disease": "", "pathway": " (ssc:407608)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "11178909;12102622;15035615", "class_list": "", "function": "Catalyzes one of the two ATP producing reactions in the glycolytic pathway via the reversible conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate. Both L- and D- forms of purine and pyrimidine nucleotides can be used as substrates, but the activity is much lower on pyrimidines. In addition to its role as a glycolytic enzyme, it seems that PGK-1 acts as a polymerase alpha cofactor protein (primer recognition protein). Acts as a protein kinase when localized to the mitochondrion where it phosphorylates pyruvate dehydrogenase kinase PDK1 to inhibit pyruvate dehydrogenase complex activity and suppress the formation of acetyl-coenzyme A from pyruvate, and consequently inhibit oxidative phosphorylation and promote glycolysis. May play a role in sperm motility., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q6B6L7", "ec_number_list": "", "go_molecular_function": "GO:0004618 phosphoglycerate kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0043531 ADP binding", "go_cellular_component": "GO:0005759 mitochondrial matrix;GO:0005829 cytosol", "go_biological_process": "GO:0006094 gluconeogenesis;GO:0006096 glycolytic process", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q7SIB7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q95342-1", "uniprot_id": "RL18_PIG", "mass": 22304.0, "length": 195, "protein_name": "Large ribosomal subunit protein eL18", "gene_name": "RPL18", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "RPL18", "gene_names_refseq": "", "protein_names_uniprotkb": "Large ribosomal subunit protein eL18; 60S ribosomal protein L18", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-156827); (R-SSC-1799339); (R-SSC-6791226); (R-SSC-72689); (R-SSC-72706); (R-SSC-975956); (R-SSC-975957); (R-SSC-9954709); (R-SSC-9954714); (R-SSC-9954716)", "pathway_count": 10, "publication_count": 2, "publication_id_list": "24930395;8672129", "class_list": "", "function": "Component of the large ribosomal subunit., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "I3L6F1", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding;GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005791 rough endoplasmic reticulum;GO:0022625 cytosolic large ribosomal subunit", "go_biological_process": "GO:0002181 cytoplasmic translation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q95342-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9GMB0-1", "uniprot_id": "RPN1_PIG", "mass": 68695.0, "length": 608, "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1", "gene_name": "RPN1", "organism": "Pig", "refseq_name": "dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 precursor", "refseq_ac": "NP_999498", "gene_names_uniprotkb": "RPN1", "gene_names_refseq": "RPN1", "protein_names_uniprotkb": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1; Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 67 kDa subunit; RPN-I; Ribophorin I; Ribophorin-1", "protein_names_refseq": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1; RPN-I; dolichyl-diphosphooligosaccharide--protein glycosyltransferase 67 kDa subunit; dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 precursor; ribophorin-1", "tax_id": 9823, "disease": "", "pathway": " (ssc:397606)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "11443278;7737165", "class_list": "", "function": "Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation (Probable). N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity (By similarity)., [UniProtKB, UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0008250 oligosaccharyltransferase complex", "go_biological_process": "GO:0009101 glycoprotein biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q9GMB0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F2Z5G5-1", "uniprot_id": "ACTZ_PIG", "mass": 39371.0, "length": 349, "protein_name": "Alpha-centractin", "gene_name": "ACTR1A", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "ACTR1A", "gene_names_refseq": "", "protein_names_uniprotkb": "Alpha-centractin; ARP1; Centractin", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-2132295); (R-SSC-2565942); (R-SSC-3371497); (R-SSC-380259); (R-SSC-380270); (R-SSC-380284); (R-SSC-380320); (R-SSC-5620912); (R-SSC-6807878); (R-SSC-8854518)", "pathway_count": 10, "publication_count": 6, "publication_id_list": "25814576;28602352;29420470;32543654;33734450;36071160", "class_list": "", "function": "Component of a multi-subunit complex involved in microtubule based vesicle motility. It is associated with the centrosome., [UniProtKB, UniProtKB]; Part of the ACTR1A/ACTB filament around which the dynactin complex is built. The dynactin multiprotein complex activates the molecular motor dynein for ultra-processive transport along microtubules., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005200 structural constituent of cytoskeleton;GO:0005524 ATP binding", "go_cellular_component": "GO:0005813 centrosome;GO:0005938 cell cortex;GO:0005869 dynactin complex;GO:0005856 cytoskeleton;GO:0005815 microtubule organizing center", "go_biological_process": "GO:0007017 microtubule-based process", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "F2Z5G5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "I3LHK5-1", "uniprot_id": "ARP10_PIG", "mass": 46197.0, "length": 417, "protein_name": "Actin-related protein 10", "gene_name": "ACTR10", "organism": "Pig", "refseq_name": "actin-related protein 10", "refseq_ac": "XP_003353540", "gene_names_uniprotkb": "ACTR10; ARP11", "gene_names_refseq": "ACTR10", "protein_names_uniprotkb": "Actin-related protein 10", "protein_names_refseq": "actin related protein 10 homolog; actin-related protein 10", "tax_id": 9823, "disease": "", "pathway": " (ssc:100620619); (R-SSC-2132295); (R-SSC-3371497); (R-SSC-6798695); (R-SSC-6807878)", "pathway_count": 5, "publication_count": 7, "publication_id_list": "25814576;28602352;29420470;30723633;32543654;33734450;36071160", "class_list": "", "function": "Part of the dynactin complex that activates the molecular motor dynein for ultra-processive transport along microtubules., [UniProtKB, PubMed, PubMed, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005200 structural constituent of cytoskeleton", "go_cellular_component": "GO:0005634 nucleus;GO:0005869 dynactin complex;GO:1904115 axon cytoplasm;GO:0005856 cytoskeleton", "go_biological_process": "GO:0007017 microtubule-based process;GO:0098958 retrograde axonal transport of mitochondrion", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "I3LHK5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P63221-1", "uniprot_id": "RS21_PIG", "mass": 9111.0, "length": 83, "protein_name": "Small ribosomal subunit protein eS21", "gene_name": "LOC100518848; RPS21", "organism": "Pig", "refseq_name": "small ribosomal subunit protein eS21", "refseq_ac": "NP_001090949", "gene_names_uniprotkb": "LOC100518848; RPS21", "gene_names_refseq": "RPS21", "protein_names_uniprotkb": "Small ribosomal subunit protein eS21; 40S ribosomal protein S21", "protein_names_refseq": "40S ribosomal protein S21; small ribosomal subunit protein eS21", "tax_id": 9823, "disease": "", "pathway": " (ssc:100037996); (ssc:100518848); (R-SSC-156827); (R-SSC-1799339); (R-SSC-72649); (R-SSC-72689); (R-SSC-72695); (R-SSC-72702); (R-SSC-72706); (R-SSC-975956); (R-SSC-975957); (R-SSC-9954714); (R-SSC-9954716)", "pathway_count": 13, "publication_count": 3, "publication_id_list": "12042320;24930395;32543654", "class_list": "", "function": "Component of the small ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A1XQV0;P35265", "ec_number_list": "", "go_molecular_function": "GO:0043022 ribosome binding;GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0045202 synapse;GO:0098556 cytoplasmic side of rough endoplasmic reticulum membrane;GO:0022627 cytosolic small ribosomal subunit;GO:0005791 rough endoplasmic reticulum;GO:0022626 cytosolic ribosome", "go_biological_process": "GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0002181 cytoplasmic translation;GO:0000461 endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0006412 translation", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "P63221-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1RRT2-1", "uniprot_id": "MYL4_PIG", "mass": 21607.0, "length": 197, "protein_name": "Myosin light chain 4", "gene_name": "MYL4", "organism": "Pig", "refseq_name": "myosin light chain 4", "refseq_ac": "XP_003131354", "gene_names_uniprotkb": "MYL4", "gene_names_refseq": "MYL4", "protein_names_uniprotkb": "Myosin light chain 4; Myosin essential light chain, atrial isoform", "protein_names_refseq": "myosin essential light chain, atrial isoform; myosin light chain 4", "tax_id": 9823, "disease": "", "pathway": " (ssc:100516998); (R-SSC-390522)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Regulatory light chain of myosin. Does not bind calcium., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003785 actin monomer binding;GO:0051015 actin filament binding;GO:0005509 calcium ion binding", "go_cellular_component": "GO:0031672 A band;GO:0016460 myosin II complex", "go_biological_process": "GO:0060048 cardiac muscle contraction;GO:0002026 regulation of the force of heart contraction", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1RRT2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SSF9-1", "uniprot_id": "MLRA_PIG", "mass": 19474.0, "length": 175, "protein_name": "Myosin regulatory light chain 2, atrial isoform", "gene_name": "GCK; MYL7", "organism": "Pig", "refseq_name": "myosin regulatory light chain 2, atrial isoform", "refseq_ac": "XP_003134933", "gene_names_uniprotkb": "GCK; MYL7; MYL2A; MYLC2A", "gene_names_refseq": "MLC-2a; MLC2a; MYL7", "protein_names_uniprotkb": "Myosin regulatory light chain 2, atrial isoform; MLC-2a; MLC2a; Myosin light chain 2a; Myosin regulatory light chain 7", "protein_names_refseq": "myosin light chain 2a; myosin regulatory light chain 2, atrial isoform; myosin regulatory light chain 7", "tax_id": 9823, "disease": "", "pathway": " (ssc:100514142); (ssc:100514437); (R-SSC-445355)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005509 calcium ion binding;GO:0004340 glucokinase activity;GO:0008865 fructokinase activity;GO:0019158 mannokinase activity;GO:0005524 ATP binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0030016 myofibril;GO:0016459 myosin complex;GO:0005634 nucleus;GO:0005741 mitochondrial outer membrane", "go_biological_process": "GO:0060047 heart contraction;GO:0048738 cardiac muscle tissue development;GO:0032024 positive regulation of insulin secretion;GO:0006006 glucose metabolic process;GO:0001678 intracellular glucose homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SSF9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P0C2C3-1", "uniprot_id": "MARC2_PIG", "mass": 4602.0, "length": 40, "protein_name": "Mitochondrial amidoxime reducing component 2", "gene_name": "MTARC2", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "MTARC2; MARC2; MOSC2", "gene_names_refseq": "", "protein_names_uniprotkb": "Mitochondrial amidoxime reducing component 2; 1.7.-.-; MOSC domain-containing protein 2; Moco sulfurase C-terminal domain-containing protein 2; Molybdenum cofactor sulfurase C-terminal domain-containing protein 2; mARC2", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 2, "publication_id_list": "16973608;21029045", "class_list": "", "function": "Catalyzes the reduction of N-oxygenated molecules, acting as a counterpart of cytochrome P450 and flavin-containing monooxygenases in metabolic cycles. As a component of prodrug-converting system, reduces a multitude of N-hydroxylated prodrugs particularly amidoximes, leading to increased drug bioavailability. May be involved in mitochondrial N(omega)-hydroxy-L-arginine (NOHA) reduction, regulating endogenous nitric oxide levels and biosynthesis. Postulated to cleave the N-OH bond of N-hydroxylated substrates in concert with electron transfer from NADH to cytochrome b5 reductase then to cytochrome b5, the ultimate electron donor that primes the active site for substrate reduction., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0016491 oxidoreductase activity", "go_cellular_component": "GO:0005741 mitochondrial outer membrane;GO:0005777 peroxisome", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "P0C2C3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P42706-1", "uniprot_id": "TPO_PIG", "mass": 2904.0, "length": 26, "protein_name": "Thrombopoietin", "gene_name": "THPO", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "THPO", "gene_names_refseq": "", "protein_names_uniprotkb": "Thrombopoietin; C-MPL ligand; MGDF; ML; Megakaryocyte colony-stimulating factor; Megakaryocyte growth and development factor", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "8202154", "class_list": "", "function": "Lineage-specific cytokine affecting the proliferation and maturation of megakaryocytes from their committed progenitor cells. It acts at a late stage of megakaryocyte development. It may be the major physiological regulator of circulating platelets., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005125 cytokine activity;GO:0005179 hormone activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0005615 extracellular space", "go_biological_process": "GO:0030219 megakaryocyte differentiation;GO:0001934 positive regulation of protein phosphorylation;GO:0051897 positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction;GO:0070374 positive regulation of ERK1 and ERK2 cascade;GO:0045654 positive regulation of megakaryocyte differentiation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "P42706-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P47788-1", "uniprot_id": "THOP1_PIG", "mass": 78144.0, "length": 687, "protein_name": "Thimet oligopeptidase", "gene_name": "THOP1", "organism": "Pig", "refseq_name": "thimet oligopeptidase", "refseq_ac": "NP_999388", "gene_names_uniprotkb": "THOP1", "gene_names_refseq": "THOP1", "protein_names_uniprotkb": "Thimet oligopeptidase; 3.4.24.15; Endopeptidase 24.15", "protein_names_refseq": "endopeptidase 24.15; thimet oligopeptidase", "tax_id": 9823, "disease": "", "pathway": " (ssc:397442)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "8168506;9182559", "class_list": "", "function": "Involved in the metabolism of neuropeptides under 20 amino acid residues long (By similarity). Involved in cytoplasmic peptide degradation. Able to degrade the amyloid-beta precursor protein and generate amyloidogenic fragments (By similarity). Also acts as a regulator of cannabinoid signaling pathway by mediating degradation of hemopressin, an antagonist peptide of the cannabinoid receptor CNR1 (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004222 metalloendopeptidase activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005758 mitochondrial intermembrane space", "go_biological_process": "GO:0006508 proteolysis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "P47788-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P49666-1", "uniprot_id": "RL21_PIG", "mass": 18565.0, "length": 160, "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "RPL21", "organism": "Pig", "refseq_name": "60S ribosomal protein L21", "refseq_ac": "XP_003482913", "gene_names_uniprotkb": "RPL21", "gene_names_refseq": "RPL21", "protein_names_uniprotkb": "Large ribosomal subunit protein eL21; 60S ribosomal protein L21", "protein_names_refseq": "60S ribosomal protein L21", "tax_id": 9823, "disease": "", "pathway": " (ssc:100736809); (R-SSC-156827); (R-SSC-1799339); (R-SSC-6791226); (R-SSC-72689); (R-SSC-72706); (R-SSC-975956); (R-SSC-975957); (R-SSC-9954709); (R-SSC-9954714); (R-SSC-9954716)", "pathway_count": 11, "publication_count": 2, "publication_id_list": "24930395;8672129", "class_list": "", "function": "Component of the large ribosomal subunit (PubMed:24930395). The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:24930395)., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "F1RTJ9", "ec_number_list": "", "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0031090 organelle membrane;GO:0022625 cytosolic large ribosomal subunit", "go_biological_process": "GO:0006412 translation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "P49666-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P62968-1", "uniprot_id": "TRH_PIG", "mass": 380.0, "length": 3, "protein_name": "Thyrotropin-releasing hormone", "gene_name": "TRH", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "TRH", "gene_names_refseq": "", "protein_names_uniprotkb": "Thyrotropin-releasing hormone; Protirelin; TRF; TRH; TSH-releasing factor; Thyroliberin; Thyrotropin-releasing factor", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 2, "publication_id_list": "4982117;4984938", "class_list": "", "function": "Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "P01151", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "P62968-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P68005-1", "uniprot_id": "PYY_PIG", "mass": 4242.0, "length": 36, "protein_name": "Peptide YY", "gene_name": "PYY", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "PYY", "gene_names_refseq": "", "protein_names_uniprotkb": "Peptide YY; PYY-II; PYY; Peptide tyrosine tyrosine", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 4, "publication_id_list": "10933813;11248248;15178255;6953409", "class_list": "", "function": "Is a NPY2R agonist involved in the down-regulation of appetite and food intake, probably acting on receptors located on proopiomelanocortin(POMC)-releasing and neuropeptide Y(NPY)-releasing neurons in the arcuate nucleus of hypothalamus. In NPY-releasing neurons, NPY2R activation by PYY(3-36) leads to membrane hyperpolarization and reduced release of the orexigenic neuropeptide NPY., [UniProtKB, UniProtKB]; Ligand for neuropeptide Y receptor type 1 (NPY1R) and neuropeptide Y receptor type 2 (NPY2R) (PubMed:11248248). Also binds NPY5R (PubMed:11248248). Receptor binding induces adenylate cyclase-inhibiting G protein-coupled receptor signaling, resulting in inhibition of cAMP production (By similarity). Receptor activation by PYY also leads to an increase of intracellular Ca(2+) levels (By similarity) (PubMed:11248248). This gut peptide inhibits exocrine pancreatic secretion (PubMed:6953409). Involved in the regulation of colonic antisecretory tone, and colonic contractility (By similarity)., [UniProtKB, UniProtKB, PubMed, PubMed, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "P01305", "ec_number_list": "", "go_molecular_function": "GO:0005179 hormone activity;GO:0031841 neuropeptide Y receptor binding", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P68005-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P79385-1", "uniprot_id": "MFGM_PIG", "mass": 45725.0, "length": 409, "protein_name": "Lactadherin", "gene_name": "MFGE8", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "MFGE8", "gene_names_refseq": "", "protein_names_uniprotkb": "Lactadherin; MFG-E8; MFGM; Milk fat globule-EGF factor 8; PP47; SED1; Sperm surface protein SP47", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "9546740", "class_list": "", "function": "Contributes to phagocytic removal of apoptotic cells in many tissues. Plays an important role in the maintenance of intestinal epithelial homeostasis and the promotion of mucosal healing. Promotes VEGF-dependent neovascularization (By similarity). Specific ligand for the alpha-v/beta-3 and alpha-v/beta-5 receptors. Also binds to phosphatidylserine-enriched cell surfaces in a receptor-independent manner. Zona pellucida-binding protein which may play a role in gamete interaction., [UniProtKB, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0001786 phosphatidylserine binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0002080 acrosomal membrane", "go_biological_process": "GO:0001525 angiogenesis;GO:0007155 cell adhesion;GO:0007338 single fertilization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "P79385-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1RGR1-1", "uniprot_id": "F1RGR1_PIG", "mass": 58599.0, "length": 532, "protein_name": "calcium/calmodulin-dependent protein kinase", "gene_name": "CAMKK1", "organism": "Pig", "refseq_name": "calcium/calmodulin-dependent protein kinase kinase 1 isoform X1", "refseq_ac": "XP_020923344", "gene_names_uniprotkb": "CAMKK1", "gene_names_refseq": "CAMKK1", "protein_names_uniprotkb": "calcium/calmodulin-dependent protein kinase; 2.7.11.17", "protein_names_refseq": "calcium/calmodulin-dependent protein kinase kinase 1 isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:503667)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005516 calmodulin binding;GO:0005524 ATP binding;GO:0004683 calcium/calmodulin-dependent protein kinase activity;GO:0004674 protein serine/threonine kinase activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005634 nucleus;GO:0005829 cytosol", "go_biological_process": "GO:0061762 CAMKK-AMPK signaling cascade", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1RGR1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q8MIR0-1", "uniprot_id": "TDH_PIG", "mass": 41432.0, "length": 373, "protein_name": "L-threonine 3-dehydrogenase, mitochondrial", "gene_name": "TDH", "organism": "Pig", "refseq_name": "L-threonine 3-dehydrogenase, mitochondrial precursor", "refseq_ac": "NP_999169", "gene_names_uniprotkb": "TDH", "gene_names_refseq": "TDH", "protein_names_uniprotkb": "L-threonine 3-dehydrogenase, mitochondrial; 1.1.1.103", "protein_names_refseq": "L-threonine 3-dehydrogenase, mitochondrial precursor; L-threonine 3-dehydrogenase, mitochondrial", "tax_id": 9823, "disease": "", "pathway": " (ssc:397065)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "12097150;32543654;7827500", "class_list": "", "function": "Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate, mediating L-threonine catabolism., [UniProtKB, PubMed, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0042802 identical protein binding;GO:0008743 L-threonine 3-dehydrogenase activity", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0019518 L-threonine catabolic process to glycine;GO:0006567 L-threonine catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q8MIR0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q29223-1", "uniprot_id": "RL34_PIG", "mass": 13293.0, "length": 117, "protein_name": "Large ribosomal subunit protein eL34", "gene_name": "RPL34", "organism": "Pig", "refseq_name": "60S ribosomal protein L34", "refseq_ac": "XP_005666999", "gene_names_uniprotkb": "RPL34", "gene_names_refseq": "RPL34", "protein_names_uniprotkb": "Large ribosomal subunit protein eL34; 60S ribosomal protein L34", "protein_names_refseq": "60S ribosomal protein L34", "tax_id": 9823, "disease": "", "pathway": " (ssc:100517840); (R-SSC-156827); (R-SSC-1799339); (R-SSC-6791226); (R-SSC-72689); (R-SSC-72706); (R-SSC-975956); (R-SSC-975957); (R-SSC-9954709); (R-SSC-9954714); (R-SSC-9954716)", "pathway_count": 11, "publication_count": 2, "publication_id_list": "24930395;8672129", "class_list": "", "function": "Component of the large ribosomal subunit (PubMed:24930395). The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:24930395)., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "F2Z5B9", "ec_number_list": "", "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0022625 cytosolic large ribosomal subunit", "go_biological_process": "GO:0006412 translation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q29223-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q29381-1", "uniprot_id": "OST48_PIG", "mass": 48863.0, "length": 439, "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit", "gene_name": "DDOST", "organism": "Pig", "refseq_name": "dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit precursor", "refseq_ac": "NP_999353", "gene_names_uniprotkb": "DDOST; OST48", "gene_names_refseq": "DDOST; OST48", "protein_names_uniprotkb": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit; DDOST 48 kDa subunit; Oligosaccharyl transferase 48 kDa subunit", "protein_names_refseq": "DDOST 48 kDa subunit; Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit; Oligosaccharyl transferase 48 kDa subunit; dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit precursor; oligosaccharyltransferase OST48", "tax_id": 9823, "disease": "", "pathway": " (ssc:397385)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "11443278;8672129", "class_list": "", "function": "Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation (PubMed:11443278). N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity (By similarity). Required for the assembly of both SST3A- and SS3B-containing OST complexes (By similarity)., [UniProtKB, PubMed, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9GL02", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane;GO:0008250 oligosaccharyltransferase complex", "go_biological_process": "GO:0009101 glycoprotein biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q29381-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q6QAP6-1", "uniprot_id": "RS29_PIG", "mass": 6600.0, "length": 56, "protein_name": "Small ribosomal subunit protein uS14", "gene_name": "RPS29", "organism": "Pig", "refseq_name": "small ribosomal subunit protein uS14", "refseq_ac": "NP_001001633", "gene_names_uniprotkb": "RPS29", "gene_names_refseq": "RPS29", "protein_names_uniprotkb": "Small ribosomal subunit protein uS14; 40S ribosomal protein S29", "protein_names_refseq": "40S ribosomal protein S29; small ribosomal subunit protein uS14", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "24930395", "class_list": "", "function": "Component of the small ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005840 ribosome;GO:0098556 cytoplasmic side of rough endoplasmic reticulum membrane;GO:0022627 cytosolic small ribosomal subunit", "go_biological_process": "GO:0002181 cytoplasmic translation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q6QAP6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A287B8J2-1", "uniprot_id": "DCTN1_PIG", "mass": 141818.0, "length": 1281, "protein_name": "Dynactin subunit 1", "gene_name": "DCTN1", "organism": "Pig", "refseq_name": "dynactin subunit 1 isoform 1", "refseq_ac": "XP_020943008", "gene_names_uniprotkb": "DCTN1", "gene_names_refseq": "DCTN1", "protein_names_uniprotkb": "Dynactin subunit 1; 150 kDa dynein-associated polypeptide; p150-glued", "protein_names_refseq": "150 kDa dynein-associated polypeptide; dynactin subunit 1 isoform 1; p150-glued", "tax_id": 9823, "disease": "", "pathway": " (ssc:100519249); (R-SSC-2132295); (R-SSC-2565942); (R-SSC-3371497); (R-SSC-380259); (R-SSC-380270); (R-SSC-380284); (R-SSC-380320); (R-SSC-5620912); (R-SSC-6807878); (R-SSC-8854518)", "pathway_count": 11, "publication_count": 3, "publication_id_list": "32543654;33734450;36071160", "class_list": "", "function": "Part of the dynactin complex that activates the molecular motor dynein for ultra-processive transport along microtubules (PubMed:33734450). Plays a key role in dynein-mediated retrograde transport of vesicles and organelles along microtubules by recruiting and tethering dynein to microtubules. Binds to both dynein and microtubules providing a link between specific cargos, microtubules and dynein. Essential for targeting dynein to microtubule plus ends, recruiting dynein to membranous cargos and enhancing dynein processivity (the ability to move along a microtubule for a long distance without falling off the track). Can also act as a brake to slow the dynein motor during motility along the microtubule. Can regulate microtubule stability by promoting microtubule formation, nucleation and polymerization and by inhibiting microtubule catastrophe in neurons. Inhibits microtubule catastrophe by binding both to microtubules and to tubulin, leading to enhanced microtubule stability along the axon. Plays a role in metaphase spindle orientation. Plays a role in centriole cohesion and subdistal appendage organization and function. Its recruitment to the centriole in a KIF3A-dependent manner is essential for the maintenance of centriole cohesion and the formation of subdistal appendage. Also required for microtubule anchoring at the mother centriole. Plays a role in primary cilia formation (By similarity)., [UniProtKB, UniProtKB, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "A0A8D1D718", "ec_number_list": "", "go_molecular_function": "GO:0008017 microtubule binding;GO:0019901 protein kinase binding;GO:0032935 sterol sensor activity", "go_cellular_component": "GO:0000922 spindle pole;GO:0005635 nuclear envelope;GO:0005813 centrosome;GO:0005829 cytosol;GO:0005938 cell cortex", "go_biological_process": "GO:0007077 mitotic nuclear membrane disassembly;GO:0007528 neuromuscular junction development;GO:0050905 neuromuscular process;GO:0051301 cell division;GO:0070050 neuron cellular homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A287B8J2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A8W4FJE3-1", "uniprot_id": "A0A8W4FJE3_PIG", "mass": 49996.0, "length": 442, "protein_name": "Platelet-activating factor acetylhydrolase", "gene_name": "PLA2G7", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "PLA2G7", "gene_names_refseq": "", "protein_names_uniprotkb": "Platelet-activating factor acetylhydrolase; 3.1.1.47", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-422085)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity;GO:0005543 phospholipid binding;GO:0004623 phospholipase A2 activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0034364 high-density lipoprotein particle;GO:0034362 low-density lipoprotein particle", "go_biological_process": "GO:0009395 phospholipid catabolic process;GO:0034638 phosphatidylcholine catabolic process;GO:0034440 lipid oxidation;GO:0034441 plasma lipoprotein particle oxidation;GO:0090026 positive regulation of monocyte chemotaxis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A0A8W4FJE3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SDV6-1", "uniprot_id": "F1SDV6_PIG", "mass": 148468.0, "length": 1291, "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma", "gene_name": "PLCG1", "organism": "Pig", "refseq_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X1", "refseq_ac": "XP_020934047", "gene_names_uniprotkb": "PLCG1", "gene_names_refseq": "PLCG1", "protein_names_uniprotkb": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; 3.1.4.11", "protein_names_refseq": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100152497); (R-SSC-1169408); (R-SSC-1855204); (R-SSC-186763); (R-SSC-201556); (R-SSC-202433); (R-SSC-2029485); (R-SSC-210990); (R-SSC-212718); (R-SSC-2424491); (R-SSC-2871796); (R-SSC-2871809); (R-SSC-5218921); (R-SSC-5654219); (R-SSC-5654228); (R-SSC-8853659); (R-SSC-9026527); (R-SSC-9034793)", "pathway_count": 18, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004435 phosphatidylinositol-4,5-bisphosphate phospholipase C activity;GO:0005509 calcium ion binding;GO:0019901 protein kinase binding;GO:0005168 neurotrophin TRKA receptor binding;GO:0120548 phosphatidylinositol phospholipase C activity", "go_cellular_component": "GO:0005829 cytosol;GO:0030027 lamellipodium;GO:0032587 ruffle membrane;GO:0008180 COP9 signalosome", "go_biological_process": "GO:0035556 intracellular signal transduction;GO:0009395 phospholipid catabolic process;GO:1905564 positive regulation of vascular endothelial cell proliferation;GO:0016477 cell migration;GO:0019722 calcium-mediated signaling", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SDV6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D0VWV4-1", "uniprot_id": "C560_PIG", "mass": 18518.0, "length": 169, "protein_name": "Succinate dehydrogenase cytochrome b560 subunit, mitochondrial", "gene_name": "SDHC", "organism": "Pig", "refseq_name": "succinate dehydrogenase cytochrome b560 subunit, mitochondrial", "refseq_ac": "XP_003125707", "gene_names_uniprotkb": "SDHC", "gene_names_refseq": "CYBL; SDHC", "protein_names_uniprotkb": "Succinate dehydrogenase cytochrome b560 subunit, mitochondrial; CYBL; Malate dehydrogenase [quinone] cytochrome b560 subunit; Succinate-ubiquinone oxidoreductase cytochrome B large subunit", "protein_names_refseq": "Succinate-ubiquinone oxidoreductase cytochrome B large subunit; malate dehydrogenase [quinone] cytochrome b560 subunit; succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa; succinate dehydrogenase cytochrome b560 subunit, mitochondrial", "tax_id": 9823, "disease": "", "pathway": " (ssc:100524676); (R-SSC-71403); (R-SSC-9854311)", "pathway_count": 3, "publication_count": 3, "publication_id_list": "15989954;17480203;32543654", "class_list": "", "function": "Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q) (PubMed:17480203). SDH also oxidizes malate to the non-canonical enol form of oxaloacetate, enol-oxaloacetate (By similarity). Enol-oxaloacetate, which is a potent inhibitor of the succinate dehydrogenase activity, is further isomerized into keto-oxaloacetate (By similarity)., [UniProtKB, PubMed, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0009055 electron transfer activity;GO:0046872 metal ion binding;GO:0020037 heme binding;GO:0043495 protein-membrane adaptor activity;GO:0008177 succinate dehydrogenase (quinone) activity", "go_cellular_component": "GO:0005743 mitochondrial inner membrane;GO:0045273 respiratory chain complex II (succinate dehydrogenase);GO:0016020 membrane;GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0006099 tricarboxylic acid cycle;GO:0006121 mitochondrial electron transport, succinate to ubiquinone", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "D0VWV4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A4L7N3-1", "uniprot_id": "FOXO1_PIG", "mass": 69921.0, "length": 662, "protein_name": "Forkhead box protein O1", "gene_name": "FOXO1", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "FOXO1; FOXO1A", "gene_names_refseq": "", "protein_names_uniprotkb": "Forkhead box protein O1; Forkhead box protein O1A; Forkhead in rhabdomyosarcoma", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "18293098", "class_list": "", "function": "Transcription factor that is the main target of insulin signaling and regulates metabolic homeostasis in response to oxidative stress (PubMed:18293098). Binds to the insulin response element (IRE) with consensus sequence 5'-TT[G/A]TTTTG-3' and the related Daf-16 family binding element (DBE) with consensus sequence 5'-TT[G/A]TTTAC-3' (By similarity). Activity suppressed by insulin (By similarity). Main regulator of redox balance and osteoblast numbers and controls bone mass (By similarity). Orchestrates the endocrine function of the skeleton in regulating glucose metabolism (By similarity). Also acts as a key regulator of chondrogenic commitment of skeletal progenitor cells in response to lipid availability: when lipids levels are low, translocates to the nucleus and promotes expression of SOX9, which induces chondrogenic commitment and suppresses fatty acid oxidation (By similarity). Acts synergistically with ATF4 to suppress osteocalcin/BGLAP activity, increasing glucose levels and triggering glucose intolerance and insulin insensitivity (By similarity). Also suppresses the transcriptional activity of RUNX2, an upstream activator of osteocalcin/BGLAP (By similarity). Acts as an inhibitor of glucose sensing in pancreatic beta cells by acting as a transcription repressor and suppressing expression of PDX1 (By similarity). In hepatocytes, promotes gluconeogenesis by acting together with PPARGC1A and CEBPA to activate the expression of genes such as IGFBP1, G6PC1 and PCK1 (By similarity). Also promotes gluconeogenesis by directly promoting expression of PPARGC1A and G6PC1 (By similarity). Important regulator of cell death acting downstream of CDK1, PKB/AKT1 and STK4/MST1 (By similarity). Promotes neural cell death (By similarity). Mediates insulin action on adipose tissue (By similarity). Regulates the expression of adipogenic genes such as PPARG during preadipocyte differentiation and, adipocyte size and adipose tissue-specific gene expression in response to excessive calorie intake (By similarity). Regulates the transcriptional activity of GADD45A and repair of nitric oxide-damaged DNA in beta-cells (By similarity). Required for the autophagic cell death induction in response to starvation or oxidative stress in a transcription-independent manner (By similarity). Mediates the function of MLIP in cardiomyocytes hypertrophy and cardiac remodeling (By similarity). Positive regulator of apoptosis in cardiac smooth muscle cells as a result of its transcriptional activation of pro-apoptotic genes (By similarity). Regulates endothelial cell (EC) viability and apoptosis in a PPIA/CYPA-dependent manner via transcription of CCL2 and BCL2L11 which are involved in EC chemotaxis and apoptosis (By similarity)., [UniProtKB, UniProtKB, UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 14, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0051721 protein phosphatase 2A binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0043565 sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0010629 negative regulation of gene expression;GO:0030154 cell differentiation;GO:0032869 cellular response to insulin stimulus", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "A4L7N3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A4PES0-1", "uniprot_id": "WEE2_PIG", "mass": 62928.0, "length": 565, "protein_name": "Wee1-like protein kinase 2", "gene_name": "WEE2", "organism": "Pig", "refseq_name": "wee1-like protein kinase 2", "refseq_ac": "NP_001090976", "gene_names_uniprotkb": "WEE2; WEE1B", "gene_names_refseq": "WEE1B; WEE2", "protein_names_uniprotkb": "Wee1-like protein kinase 2; 2.7.10.2; Wee1-like protein kinase 1B; Wee1B kinase; pWee1B; pigWee1B", "protein_names_refseq": "WEE1 homolog 2; Wee1-like protein kinase 1B; Wee1B protein kinase; wee1-like protein kinase 2", "tax_id": 9823, "disease": "", "pathway": " (ssc:100048934)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "19550110;19633431;21123961", "class_list": "", "function": "Insufficient amount of Cdc2 and continuous activation of Wee1 B are the cause of meiotic failure of small oocytes in pigs, [RefSeq, PubMed]; Oocyte-specific protein tyrosine kinase that phosphorylates and inhibits CDK1 and acts as a key regulator of meiosis during both prophase I and metaphase II. Required to maintain meiotic arrest in oocytes during the germinal vesicle (GV) stage, a long period of quiescence at dictyate prophase I, by phosphorylating CDK1 at 'Tyr-15', leading to inhibit CDK1 activity and prevent meiotic reentry. Also required for metaphase II exit during egg activation by phosphorylating CDK1 at 'Tyr-15', to ensure exit from meiosis in oocytes and promote pronuclear formation., [UniProtKB, PubMed]; Results suggest pWEE1B is activated after phosphorylation of the Ser77 residue, which is different from phosphorylation site that activates mWEE1B; that pWEE1B is localized in the nucleus; and that the nuclear localization is essential for its function, [RefSeq, PubMed]; These results suggest that the inhibitory phosphorylation of CDC2, which is catalyzed by pigWee1B, but not pigMyt1, is involved in the meiotic arrest of porcine oocytes., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 5, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0004713 protein tyrosine kinase activity;GO:0004715 non-membrane spanning protein tyrosine kinase activity;GO:0005524 ATP binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0060283 negative regulation of oocyte development;GO:0000278 mitotic cell cycle;GO:0007143 female meiotic nuclear division;GO:0042327 positive regulation of phosphorylation;GO:0060631 regulation of meiosis I", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A4PES0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A5GZW8-1", "uniprot_id": "DHSD_PIG", "mass": 17005.0, "length": 159, "protein_name": "Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial", "gene_name": "SDHD", "organism": "Pig", "refseq_name": "succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial", "refseq_ac": "NP_001090985", "gene_names_uniprotkb": "SDHD", "gene_names_refseq": "CII-4; CybS; QPs3; SDHD", "protein_names_uniprotkb": "Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial; CII-4; CybS; Malate dehydrogenase [quinone] cytochrome b small subunit; QPs3; Succinate dehydrogenase complex subunit D; Succinate-ubiquinone oxidoreductase cytochrome b small subunit; Succinate-ubiquinone reductase membrane anchor subunit", "protein_names_refseq": "Succinate-ubiquinone oxidoreductase cytochrome b small subunit; Succinate-ubiquinone reductase membrane anchor subunit; malate dehydrogenase [quinone] cytochrome b small subunit; succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial; succinate dehydrogenase complex, subunit D, integral membrane protein", "tax_id": 9823, "disease": "", "pathway": " (ssc:100048954)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "15989954;17550355;17651329", "class_list": "", "function": "Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q) (PubMed:15989954). SDH also oxidizes malate to the non-canonical enol form of oxaloacetate, enol-oxaloacetate (By similarity). Enol-oxaloacetate, which is a potent inhibitor of the succinate dehydrogenase activity, is further isomerized into keto-oxaloacetate (By similarity)., [UniProtKB, PubMed, UniProtKB]; Single nucleotide polymorphisms are associated with growth and meat quality traits in pigs., [RefSeq, PubMed]; The expression and sequencing of SDHD and single nucleotide polymorphisms of the gene are reported., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A7E1T4;A7E1T8", "ec_number_list": "", "go_molecular_function": "GO:0046872 metal ion binding;GO:0020037 heme binding;GO:0043495 protein-membrane adaptor activity;GO:0048039 ubiquinone binding", "go_cellular_component": "GO:0005743 mitochondrial inner membrane;GO:0045273 respiratory chain complex II (succinate dehydrogenase)", "go_biological_process": "GO:0006099 tricarboxylic acid cycle;GO:0006121 mitochondrial electron transport, succinate to ubiquinone", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A5GZW8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "C0HL13-1", "uniprot_id": "LRP2_PIG", "mass": 521302.0, "length": 4652, "protein_name": "Low-density lipoprotein receptor-related protein 2", "gene_name": "LRP2", "organism": "Pig", "refseq_name": "low-density lipoprotein receptor-related protein 2 precursor", "refseq_ac": "XP_020931970", "gene_names_uniprotkb": "LRP2", "gene_names_refseq": "LRP-2; LRP2; gp330", "protein_names_uniprotkb": "Low-density lipoprotein receptor-related protein 2; Glycoprotein 330; LRP-2; Megalin; gp330", "protein_names_refseq": "glycoprotein 330; low-density lipoprotein receptor-related protein 2 precursor; low-density lipoprotein receptor-related protein 2; megalin", "tax_id": 9823, "disease": "", "pathway": " (ssc:100519689)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "11964399;29954945;9228033", "class_list": "", "function": "Multiligand endocytic receptor (By similarity). Acts together with CUBN to mediate endocytosis of high-density lipoproteins (By similarity). Mediates receptor-mediated uptake of polybasic drugs such as aprotinin, aminoglycosides and polymyxin B (By similarity). In the kidney, mediates the tubular uptake and clearance of leptin (By similarity). Also mediates transport of leptin across the blood-brain barrier through endocytosis at the choroid plexus epithelium (By similarity). Endocytosis of leptin in neuronal cells is required for hypothalamic leptin signaling and leptin-mediated regulation of feeding and body weight (By similarity). Mediates endocytosis and subsequent lysosomal degradation of CST3 in kidney proximal tubule cells (By similarity). Mediates renal uptake of 25-hydroxyvitamin D3 in complex with the vitamin D3 transporter GC/DBP (By similarity). Mediates renal uptake of metallothionein-bound heavy metals (By similarity). Together with CUBN, mediates renal reabsorption of myoglobin (By similarity). Mediates renal uptake and subsequent lysosomal degradation of APOM (By similarity). Plays a role in kidney selenium homeostasis by mediating renal endocytosis of selenoprotein SEPP1 (By similarity). Mediates renal uptake of the antiapoptotic protein BIRC5/survivin which may be important for functional integrity of the kidney (By similarity). Mediates renal uptake of matrix metalloproteinase MMP2 in complex with metalloproteinase inhibitor TIMP1 (By similarity). Mediates endocytosis of Sonic hedgehog protein N-product (ShhN), the active product of SHH (By similarity). Also mediates ShhN transcytosis (By similarity). In the embryonic neuroepithelium, mediates endocytic uptake and degradation of BMP4, is required for correct SHH localization in the ventral neural tube and plays a role in patterning of the ventral telencephalon (By similarity). Required at the onset of neurulation to sequester SHH on the apical surface of neuroepithelial cells of the rostral diencephalon ventral midline and to control PTCH1-dependent uptake and intracellular trafficking of SHH (By similarity). During neurulation, required in neuroepithelial cells for uptake of folate bound to the folate receptor FOLR1 which is necessary for neural tube closure (By similarity). In the adult brain, negatively regulates BMP signaling in the subependymal zone which enables neurogenesis to proceed (By similarity). In astrocytes, mediates endocytosis of ALB which is required for the synthesis of the neurotrophic factor oleic acid (By similarity). Involved in neurite branching (By similarity). During optic nerve development, required for SHH-mediated migration and proliferation of oligodendrocyte precursor cells (By similarity). Mediates endocytic uptake and clearance of SHH in the retinal margin which protects retinal progenitor cells from mitogenic stimuli and keeps them quiescent (By similarity). Plays a role in reproductive organ development by mediating uptake in reproductive tissues of androgen and estrogen bound to the sex hormone binding protein SHBG (By similarity). Mediates endocytosis of angiotensin-2 (By similarity). Also mediates endocytosis of angiotensis 1-7 (By similarity). Binds to the complex composed of beta-amyloid protein 40 and CLU/APOJ and mediates its endocytosis and lysosomal degradation (PubMed:9228033). Required for embryonic heart development (By similarity). Required for normal hearing, possibly through interaction with estrogen in the inner ear (By similarity)., [UniProtKB, UniProtKB, UniProtKB, PubMed, UniProtKB]", "predicted_glycosites": 42, "predicted_n_glycosites": 41, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 42, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0017124 SH3 domain binding;GO:0051087 protein-folding chaperone binding;GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005905 clathrin-coated pit;GO:0030424 axon;GO:0030425 dendrite;GO:0031904 endosome lumen;GO:0043235 receptor complex", "go_biological_process": "GO:1905167 positive regulation of lysosomal protein catabolic process;GO:0008584 male gonad development;GO:0001843 neural tube closure;GO:0030514 negative regulation of BMP signaling pathway;GO:0006898 receptor-mediated endocytosis", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "C0HL13-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1RKQ4-1", "uniprot_id": "TKFC_PIG", "mass": 59234.0, "length": 579, "protein_name": "Triokinase/FMN cyclase", "gene_name": "TKFC", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "TKFC; DAK", "gene_names_refseq": "", "protein_names_uniprotkb": "Triokinase/FMN cyclase; Bifunctional ATP-dependent dihydroxyacetone kinase/FAD-AMP lyase (cyclizing); FAD-AMP lyase (cyclic FMN forming); FMN cyclase; Glycerone kinase; Triokinase; Triose kinase", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "7831203", "class_list": "", "function": "Catalyzes both the phosphorylation of dihydroxyacetone and of glyceraldehyde, and the splitting of ribonucleoside diphosphate-X compounds among which FAD is the best substrate (PubMed:7831203). Represses IFIH1-mediated cellular antiviral response (By similarity)., [UniProtKB, PubMed, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9TR81", "ec_number_list": "", "go_molecular_function": "GO:0004371 glycerone kinase activity;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0034012 FAD-AMP lyase (cyclizing) activity;GO:0050354 triokinase activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0019563 glycerol catabolic process;GO:0039534 negative regulation of MDA-5 signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1RKQ4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1RRV3-1", "uniprot_id": "THYG_PIG", "mass": 293030.0, "length": 2692, "protein_name": "Thyroglobulin", "gene_name": "TG", "organism": "Pig", "refseq_name": "thyroglobulin precursor", "refseq_ac": "NP_001161890", "gene_names_uniprotkb": "TG", "gene_names_refseq": "TG", "protein_names_uniprotkb": "Thyroglobulin", "protein_names_refseq": "thyroglobulin precursor", "tax_id": 9823, "disease": "", "pathway": " (ssc:100156471)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "11082042;12325367;12387814;7021557", "class_list": "", "function": "Acts as a substrate for the production of iodinated thyroid hormones thyroxine (T4) and triiodothyronine (T3) (PubMed:7021557). The synthesis of T3 and T4 involves iodination of selected tyrosine residues of TG/thyroglobulin followed by their oxidative coupling (PubMed:7021557). Following TG re-internalization and lysosomal-mediated proteolysis, T3 and T4 are released from the polypeptide backbone leading to their secretion into the bloodstream (By similarity). One dimer produces 7 thyroid hormone molecules (By similarity)., [UniProtKB, UniProtKB, UniProtKB, PubMed]", "predicted_glycosites": 15, "predicted_n_glycosites": 15, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 15, "binding_glycan_count": 0, "secondary_ac_list": "D1KKB3", "ec_number_list": "", "go_molecular_function": "GO:0042802 identical protein binding;GO:0005179 hormone activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0042446 hormone biosynthetic process;GO:0006590 thyroid hormone generation", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "F1RRV3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1RWC3-1", "uniprot_id": "CUBN_PIG", "mass": 397366.0, "length": 3625, "protein_name": "Cubilin", "gene_name": "CUBN", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "CUBN; IFCR", "gene_names_refseq": "", "protein_names_uniprotkb": "Cubilin; Intrinsic factor-cobalamin receptor", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "30523278", "class_list": "", "function": "Endocytic receptor which plays a role in lipoprotein, vitamin and iron metabolism by facilitating their uptake. Acts together with LRP2 to mediate endocytosis of high-density lipoproteins, GC, hemoglobin, ALB, TF and SCGB1A1. Acts together with AMN to mediate endocytosis of the CBLIF-cobalamin complex. Binds to ALB, MB, Kappa and lambda-light chains, TF, hemoglobin, GC, SCGB1A1, APOA1, high density lipoprotein, and the CBLIF-cobalamin complex. Ligand binding requires calcium. Serves as important transporter in several absorptive epithelia, including intestine, renal proximal tubules and embryonic yolk sac. May play an important role in the development of the peri-implantation embryo through internalization of APOA1 and cholesterol. Binds to LGALS3 at the maternal-fetal interface., [UniProtKB, UniProtKB]", "predicted_glycosites": 44, "predicted_n_glycosites": 44, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 44, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004252 serine-type endopeptidase activity;GO:0005509 calcium ion binding;GO:0031419 cobalamin binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005768 endosome;GO:0005905 clathrin-coated pit;GO:0005765 lysosomal membrane;GO:0016324 apical plasma membrane", "go_biological_process": "GO:0008203 cholesterol metabolic process;GO:0015031 protein transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1RWC3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "I3LGZ3-1", "uniprot_id": "GL15L_PIG", "mass": 9214.0, "length": 81, "protein_name": "Protein GPR15LG", "gene_name": "GPR15LG", "organism": "Pig", "refseq_name": "protein GPR15LG precursor", "refseq_ac": "NP_001230830", "gene_names_uniprotkb": "GPR15LG; GPR15L", "gene_names_refseq": "C10orf99; C14H10orf99; GPR15LG; GPR15L; GPRL15", "protein_names_uniprotkb": "Protein GPR15LG; Protein GPR15 ligand; Protein GPR15L", "protein_names_refseq": "chromosome 14 C10orf99 homolog; protein GPR15 ligand; protein GPR15LG precursor; protein GPR15LG; protein GPR15L; secreted protein C10orf99 homolog", "tax_id": 9823, "disease": "", "pathway": " (ssc:100511838)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "28900043", "class_list": "", "function": "Has antimicrobial activity against Gram-positive bacteria, including Staphylococcus aureus and Actinomyces spec., and Mycoplasma hominis and lentivirus., [UniProtKB, UniProtKB]; Highly cationic protein that has multiple functions. Acts as a chemotactic factor that mediates lymphocytes recruitment to epithelia through binding and activation of the G protein-coupled receptor GPR15 (PubMed:28900043). May be a tumor suppressor; together with SUSD2 has a growth inhibitory effect on colon cancer cells which includes G1 cell cycle arrest. May regulate keratinocyte proliferation. In addition, through activation of Mas-related G protein-coupled receptors (MRGPRs) contributes to pruritogenesis by activating itch-selective sensory neurons and mast cells degranulation (By similarity)., [UniProtKB, UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0001664 G protein-coupled receptor binding;GO:0048018 receptor ligand activity;GO:0008009 chemokine activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0001525 angiogenesis;GO:0007186 G protein-coupled receptor signaling pathway;GO:0050830 defense response to Gram-positive bacterium;GO:0048247 lymphocyte chemotaxis;GO:0043029 T cell homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "I3LGZ3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "O02696-1", "uniprot_id": "PI3R5_PIG", "mass": 96994.0, "length": 877, "protein_name": "Phosphoinositide 3-kinase regulatory subunit 5", "gene_name": "PIK3R5", "organism": "Pig", "refseq_name": "phosphoinositide 3-kinase regulatory subunit 5", "refseq_ac": "NP_999016", "gene_names_uniprotkb": "PIK3R5", "gene_names_refseq": "P101; PIK3R5", "protein_names_uniprotkb": "Phosphoinositide 3-kinase regulatory subunit 5; IB PI3-kinase p101 subunit; PI3-kinase p101 subunit; PI3-kinase regulatory subunit 5; Phosphatidylinositol 4,5-bisphosphate 3-kinase regulatory subunit; PtdIns-3-kinase p101; PtdIns-3-kinase regulatory subunit; p101-PI3K", "protein_names_refseq": "IB PI3-kinase p101 subunit; PI3-kinase p101 subunit; PI3-kinase regulatory subunit 5; p101-PI3K; phosphatidylinositol 4,5-bisphosphate 3-kinase regulatory subunit; phosphoinositide 3-kinase regulatory subunit 5; ptdIns-3-kinase p101; ptdIns-3-kinase regulatory subunit", "tax_id": 9823, "disease": "", "pathway": " (ssc:396851)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "12507995;15611065;9094719", "class_list": "", "function": "Regulatory subunit of the PI3K gamma complex. Required for recruitment of the catalytic subunit to the plasma membrane via interaction with beta-gamma G protein dimers. Required for G protein-mediated activation of PIK3CG., [UniProtKB, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0031683 G-protein beta/gamma-subunit complex binding;GO:0046935 1-phosphatidylinositol-3-kinase regulator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0016020 membrane;GO:0005944 phosphatidylinositol 3-kinase complex, class IB", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway;GO:0051897 positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction;GO:0043406 positive regulation of MAP kinase activity;GO:0043491 phosphatidylinositol 3-kinase/protein kinase B signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "O02696-1", "record_type": "protein" }, { "uniprot_canonical_ac": "O18734-1", "uniprot_id": "PP14A_PIG", "mass": 16672.0, "length": 147, "protein_name": "Protein phosphatase 1 regulatory subunit 14A", "gene_name": "CPI17", "organism": "Pig", "refseq_name": "protein phosphatase 1 regulatory subunit 14A", "refseq_ac": "NP_999502", "gene_names_uniprotkb": "CPI17", "gene_names_refseq": "CPI17; PPP1R14A", "protein_names_uniprotkb": "Protein phosphatase 1 regulatory subunit 14A; 17 kDa PKC-potentiated inhibitory protein of PP1; CPI-17; Protein kinase C-potentiated inhibitor protein of 17 kDa", "protein_names_refseq": "17-kDa PKC-potentiated inhibitory protein of PP1; CPI-17; protein kinase C-potentiated inhibitor protein of 17 kDa; protein phosphatase 1 regulatory subunit 14A", "tax_id": 9823, "disease": "", "pathway": " (ssc:397610); (R-SSC-5625740)", "pathway_count": 2, "publication_count": 8, "publication_id_list": "10869555;10924361;11517233;11734001;12595264;24058600;8720121;9237662", "class_list": "", "function": "Inhibitor of PPP1CA. Has over 1000-fold higher inhibitory activity when phosphorylated, creating a molecular switch for regulating the phosphorylation status of PPP1CA substrates and smooth muscle contraction., [UniProtKB, PubMed, PubMed, PubMed, PubMed]; This study examined the protein expression and spatial-temporal distribution of PKCalpha and CPI-17 in intact smooth muscle tissues. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 6, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9TQZ8;Q9TQZ9;Q9TR00;Q9TR01;Q9TR02", "ec_number_list": "", "go_molecular_function": "GO:0004865 protein serine/threonine phosphatase inhibitor activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "O18734-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A4X1TB62-1", "uniprot_id": "DCTN4_PIG", "mass": 52848.0, "length": 467, "protein_name": "Dynactin subunit 4", "gene_name": "DCTN4", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "DCTN4", "gene_names_refseq": "", "protein_names_uniprotkb": "Dynactin subunit 4; Dyn4", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-2132295); (R-SSC-3371497); (R-SSC-6807878)", "pathway_count": 3, "publication_count": 3, "publication_id_list": "32543654;33734450;36071160", "class_list": "", "function": "Part of the dynactin complex that activates the molecular motor dynein for ultra-processive transport along microtubules (PubMed:33734450, PubMed:36071160). Together with dynein is involved in spindle assembly and cytokinesis (By similarity)., [UniProtKB, PubMed, PubMed, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005813 centrosome;GO:0005938 cell cortex;GO:0001725 stress fiber;GO:0030017 sarcomere;GO:0005869 dynactin complex", "go_biological_process": "GO:0007017 microtubule-based process", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "A0A4X1TB62-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P55791-1", "uniprot_id": "PNOC_PIG", "mass": 1809.0, "length": 17, "protein_name": "Nociceptin", "gene_name": "PNOC", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "PNOC", "gene_names_refseq": "", "protein_names_uniprotkb": "Nociceptin; Orphanin FQ", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "7481766", "class_list": "", "function": "Ligand of the opioid receptor-like receptor OPRL1. It may act as a transmitter in the brain by modulating nociceptive and locomotor behavior. May be involved in neuronal differentiation and development. When administered intracerebroventricularly into mice, this peptide induces hyperalgesia and decreases locomotor activity., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0001515 opioid peptide activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0045202 synapse", "go_biological_process": "GO:0007218 neuropeptide signaling pathway;GO:0007268 chemical synaptic transmission", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "P55791-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P00889-1", "uniprot_id": "CISY_PIG", "mass": 51629.0, "length": 464, "protein_name": "Citrate synthase, mitochondrial", "gene_name": "CS", "organism": "Pig", "refseq_name": "citrate synthase, mitochondrial precursor", "refseq_ac": "NP_999441", "gene_names_uniprotkb": "CS", "gene_names_refseq": "CS", "protein_names_uniprotkb": "Citrate synthase, mitochondrial; 2.3.3.1; Citrate (Si)-synthase", "protein_names_refseq": "citrate (Si)-synthase; citrate synthase, mitochondrial precursor; citrate synthase, mitochondrial", "tax_id": 9823, "disease": "", "pathway": " (ssc:397519); (R-SSC-71403); (R-SSC-9837999); (R-SSC-9854311)", "pathway_count": 4, "publication_count": 9, "publication_id_list": "1702991;17486291;19407370;26241964;3048387;31141475;32543654;7093227;7120407", "class_list": "", "function": "In pig heart CS, both symmetric (suggested by crystallography) and asymmetric motions are features of the protein structure, and as a result the behaviour in solution is largely non-cooperative. Publication Status: Online-Only, [RefSeq, PubMed]; Key enzyme of the Krebs tricarboxylic acid cycle which catalyzes the synthesis of citrate from acetyl coenzyme A and oxaloacetate., [UniProtKB, UniProtKB, UniProtKB]; Structure was refined to an R factor of 0.179 (R(free) = 0.222) using synchrotron data to a resolution of 1.78 A, [RefSeq, PubMed]; Thermostabilization of thermosensitive CS by small heat shock proteins is achieved by stabilization of the C- and N-terminae in the protruding thermosensitive softspot., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 6, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0042802 identical protein binding;GO:0036440 citrate synthase activity", "go_cellular_component": "GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0006099 tricarboxylic acid cycle;GO:0006101 citrate metabolic process;GO:0005975 carbohydrate metabolic process", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P00889-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P82125-1", "uniprot_id": "AKCL2_PIG", "mass": 34107.0, "length": 301, "protein_name": "1,5-anhydro-D-fructose reductase", "gene_name": "AKR1E2", "organism": "Pig", "refseq_name": "1,5-anhydro-D-fructose reductase", "refseq_ac": "NP_001038033", "gene_names_uniprotkb": "AKR1E2; AKR1CL2", "gene_names_refseq": "AKR1CL2; AKR1E2", "protein_names_uniprotkb": "1,5-anhydro-D-fructose reductase; 1.1.1.263; AF reductase; Aldo-keto reductase family 1 member C-like protein 2; Aldo-keto reductase family 1 member CL2; Aldo-keto reductase family 1 member E2", "protein_names_refseq": "1,5-anhydro-D-fructose reductase; AF reductase; Aldo-keto reductase family 1 member C-like protein 2; Aldo-keto reductase family 1 member CL2; putative aldo-keto reductase family 1 member CL2", "tax_id": 9823, "disease": "", "pathway": " (ssc:733633); (R-SSC-70221)", "pathway_count": 2, "publication_count": 4, "publication_id_list": "14681463;16970816;32543654;9504428", "class_list": "", "function": "Catalyzes the NADPH-dependent reduction of 1,5-anhydro-D-fructose (AF) to 1,5-anhydro-D-glucitol., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q1KLB5", "ec_number_list": "", "go_molecular_function": "GO:0004032 aldose reductase (NADPH) activity;GO:0050571 1,5-anhydro-D-fructose reductase activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P82125-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P10668-1", "uniprot_id": "COF1_PIG", "mass": 18519.0, "length": 166, "protein_name": "Cofilin-1", "gene_name": "CFL1", "organism": "Pig", "refseq_name": "cofilin-1", "refseq_ac": "NP_001004043", "gene_names_uniprotkb": "CFL1", "gene_names_refseq": "CFL1; COFILIN", "protein_names_uniprotkb": "Cofilin-1; Cofilin, non-muscle isoform", "protein_names_refseq": "cofilin-1", "tax_id": 9823, "disease": "", "pathway": " (ssc:445532)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "18093681;19109524;23951242;32543654;3403546;6509022;8672129;9078368", "class_list": "", "function": "Binds to F-actin and exhibits pH-sensitive F-actin depolymerizing activity (PubMed:6509022, PubMed:9078368). In conjunction with the subcortical maternal complex (SCMC), plays an essential role for zygotes to progress beyond the first embryonic cell divisions via regulation of actin dynamics (PubMed:9078368). Required for the centralization of the mitotic spindle and symmetric division of zygotes (By similarity). Plays a role in the regulation of cell morphology and cytoskeletal organization in epithelial cells (By similarity). Required for the up-regulation of atypical chemokine receptor ACKR2 from endosomal compartment to cell membrane, increasing its efficiency in chemokine uptake and degradation (By similarity). Required for neural tube morphogenesis and neural crest cell migration (By similarity)., [UniProtKB, UniProtKB, UniProtKB, PubMed, PubMed]; Cofilin is necessary for maintaining the osmotic responsiveness of the cytoskeleton in tubular cells, and the Rho/ROCK/LIMK-mediated cofilin phosphorylation is a key mechanism in the hyperosmotic stress-induced F-actin increase., [RefSeq, PubMed]; Glucose increases p-cofilin by phosphorylating LIMK1 through activation of Rho/Rho kinase, probably due to diacylglycerol-sensitive PKC activation resulting from increased glucose influx, [RefSeq, PubMed]; In vitro, formation of cofilin oligomers was drastically reduced after phosphorylation by LIMK2. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 7, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q29374", "ec_number_list": "", "go_molecular_function": "GO:0051015 actin filament binding;GO:0003779 actin binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0015629 actin cytoskeleton;GO:0030027 lamellipodium;GO:0030426 growth cone;GO:0016363 nuclear matrix", "go_biological_process": "GO:0051293 establishment of spindle localization;GO:0007015 actin filament organization;GO:0000281 mitotic cytokinesis;GO:0040019 positive regulation of embryonic development;GO:0051014 actin filament severing", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P10668-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q6QAQ1-1", "uniprot_id": "ACTB_PIG", "mass": 41737.0, "length": 375, "protein_name": "Actin, cytoplasmic 1", "gene_name": "ACTB", "organism": "Pig", "refseq_name": "actin, cytoplasmic 1", "refseq_ac": "XP_003124328", "gene_names_uniprotkb": "ACTB", "gene_names_refseq": "ACTB", "protein_names_uniprotkb": "Actin, cytoplasmic 1; 3.6.4.-; Beta-actin", "protein_names_refseq": "actin, cytoplasmic 1; cytoskeletal beta actin", "tax_id": 9823, "disease": "", "pathway": " (ssc:414396); (R-SSC-114608); (R-SSC-190873); (R-SSC-196025); (R-SSC-2029482); (R-SSC-3928662); (R-SSC-418990); (R-SSC-4420097); (R-SSC-446353); (R-SSC-5626467); (R-SSC-5663213); (R-SSC-5663220); (R-SSC-5674135); (R-SSC-5689603); (R-SSC-8856828); (R-SSC-9035034); (R-SSC-9764561); (R-SSC-9913351); (R-SSC-9933937); (R-SSC-9933939); (R-SSC-9933946); (R-SSC-9933947); (R-SSC-9953170); (R-SSC-9958825)", "pathway_count": 24, "publication_count": 5, "publication_id_list": "25814576;29420470;32543654;33734450;36071160", "class_list": "", "function": "Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells (By similarity). Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction (By similarity). In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA (By similarity). Plays a role in the assembly of the gamma-tubulin ring complex (gTuRC), which regulates the minus-end nucleation of alpha-beta tubulin heterodimers that grow into microtubule protafilaments (By similarity). Part of the ACTR1A/ACTB filament around which the dynactin complex is built (PubMed:25814576, PubMed:29420470, PubMed:33734450, PubMed:36071160). The dynactin multiprotein complex activates the molecular motor dynein for ultra-processive transport along microtubules (PubMed:25814576, PubMed:29420470, PubMed:33734450, PubMed:36071160)., [UniProtKB, PubMed, PubMed, PubMed, UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0019901 protein kinase binding;GO:0042802 identical protein binding;GO:0016887 ATP hydrolysis activity;GO:0019894 kinesin binding", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0044305 calyx of Held;GO:0098871 postsynaptic actin cytoskeleton;GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0007409 axonogenesis;GO:0001738 morphogenesis of a polarized epithelium;GO:1903076 regulation of protein localization to plasma membrane;GO:0048870 cell motility;GO:0007163 establishment or maintenance of cell polarity", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q6QAQ1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P28491-1", "uniprot_id": "CALR_PIG", "mass": 48288.0, "length": 417, "protein_name": "Calreticulin", "gene_name": "CALR", "organism": "Pig", "refseq_name": "calreticulin precursor", "refseq_ac": "NP_001167604", "gene_names_uniprotkb": "CALR", "gene_names_refseq": "CALR; CRP55; Calregulin; ERp60; HACBP", "protein_names_uniprotkb": "Calreticulin; CRP55; Calregulin; ERp60; Endoplasmic reticulum resident protein 60; HACBP", "protein_names_refseq": "Endoplasmic reticulum resident protein 60; calreticulin precursor", "tax_id": 9823, "disease": "", "pathway": " (ssc:100381266); (R-SSC-3000480); (R-SSC-901042); (R-SSC-983170)", "pathway_count": 4, "publication_count": 6, "publication_id_list": "2016321;20222029;24398873;28770174;32543654;8672129", "class_list": "", "function": "Calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export (By similarity). Involved in maternal gene expression regulation. May participate in oocyte maturation via the regulation of calcium homeostasis (PubMed:20222029). Present in the cortical granules of non-activated oocytes, is exocytosed during the cortical reaction in response to oocyte activation and might participate in the block to polyspermy (By similarity)., [UniProtKB, UniProtKB, PubMed, UniProtKB]; Calreticulin is confined to subplasmalemmal vesicles partially overlapping with cortical granule contents. Its exocytosis after the oocyte activation seems to participate in the membrane block to polyspermy in pigs. Publication Status: Online-Only, [RefSeq, PubMed]; Calreticulin was widely expressed in pig tissues and its transcripts were downregulated during maturation, especially at 44 hr, and were undetectable at the blastocyst stage., [RefSeq, PubMed]; Here the authors identify porcine calreticulin expressed by swine intestinal cells as a host-specific receptor for Salmonella Choleraesuis FimH adhesin, suggesting that such an interaction may contribute to Salmonella Choleraesuis host specificity. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "D4N5N1", "ec_number_list": "", "go_molecular_function": "GO:0003729 mRNA binding;GO:0005178 integrin binding;GO:0051082 unfolded protein binding;GO:0031625 ubiquitin protein ligase binding;GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005635 nuclear envelope;GO:0005829 cytosol;GO:0048471 perinuclear region of cytoplasm;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0008284 positive regulation of cell population proliferation;GO:0010628 positive regulation of gene expression;GO:0045665 negative regulation of neuron differentiation;GO:0010595 positive regulation of endothelial cell migration", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P28491-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P01297-1", "uniprot_id": "NMB_PIG", "mass": 13381.0, "length": 121, "protein_name": "Neuromedin-B", "gene_name": "NMB", "organism": "Pig", "refseq_name": "neuromedin-B precursor", "refseq_ac": "NP_001116617", "gene_names_uniprotkb": "NMB", "gene_names_refseq": "NMB", "protein_names_uniprotkb": "Neuromedin-B", "protein_names_refseq": "Neuromedin-B; neuromedin-B precursor", "tax_id": 9823, "disease": "", "pathway": " (ssc:100141313); (R-SSC-375276); (R-SSC-416476)", "pathway_count": 3, "publication_count": 5, "publication_id_list": "27010315;29632025;32543654;4026853;6882442", "class_list": "", "function": "In sow estrous cycle, the hypothalamic levels of both NMB and NMBR mRAN were similar, but the expression levels of the pituitary were negatively correlated. Publication Status: Online-Only, [RefSeq, PubMed]; Stimulates smooth muscle contraction (PubMed:6882442). Induces sighing by acting directly on the pre-Botzinger complex, a cluster of several thousand neurons in the ventrolateral medulla responsible for inspiration during respiratory activity (By similarity). Contributes to the induction of sneezing following exposure to chemical irritants or allergens which causes release of NMB by nasal sensory neurons and activation of NMBR-expressing neurons in the sneeze-evoking region of the brainstem (By similarity). These in turn activate neurons of the caudal ventral respiratory group, giving rise to the sneezing response (By similarity). Contributes to induction of acute itch, possibly through activation of the NMBR receptor on dorsal root ganglion neurons (By similarity). Increases expression of NMBR and steroidogenic mediators STAR, CYP11A1 and HSD3B1 in Leydig cells, induces secretion of testosterone by Leydig cells and also promotes Leydig cell proliferation (PubMed:29632025). Plays a role in the innate immune response to influenza A virus infection by enhancing interferon alpha expression and reducing expression of IL6 (By similarity). Plays a role in CSF1-induced proliferation of osteoclast precursors by contributing to positive regulation of the expression of the CSF1 receptor CSF1R (By similarity)., [UniProtKB, PubMed, PubMed, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A4X1UK00", "ec_number_list": "", "go_molecular_function": "GO:0005184 neuropeptide hormone activity;GO:0031710 neuromedin B receptor binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0043005 neuron projection;GO:0005576 extracellular region", "go_biological_process": "GO:0032727 positive regulation of interferon-alpha production;GO:0007218 neuropeptide signaling pathway;GO:0032715 negative regulation of interleukin-6 production;GO:0046887 positive regulation of hormone secretion;GO:0090290 positive regulation of osteoclast proliferation", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P01297-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P68137-1", "uniprot_id": "ACTS_PIG", "mass": 42051.0, "length": 377, "protein_name": "Actin, alpha skeletal muscle", "gene_name": "ACTA1", "organism": "Pig", "refseq_name": "actin, alpha skeletal muscle", "refseq_ac": "NP_001161267", "gene_names_uniprotkb": "ACTA1; ACTA", "gene_names_refseq": "ACTA1; ACTA", "protein_names_uniprotkb": "Actin, alpha skeletal muscle; 3.6.4.-; Alpha-actin-1", "protein_names_refseq": "actin, alpha skeletal muscle; alpha actin 1; beta actin; skeletal alpha actin", "tax_id": 9823, "disease": "", "pathway": " (ssc:100154254)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "22162634;24743229;32543654;8973342", "class_list": "", "function": "Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells., [UniProtKB]; Titin-actin interaction: PEVK-actin-based viscosity in a large animal., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "P02568;P99020", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0016787 hydrolase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005884 actin filament;GO:0030027 lamellipodium;GO:0001725 stress fiber", "go_biological_process": "GO:0010628 positive regulation of gene expression;GO:0030240 skeletal muscle thin filament assembly;GO:0048741 skeletal muscle fiber development;GO:0090131 mesenchyme migration", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P68137-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P41367-1", "uniprot_id": "ACADM_PIG", "mass": 46485.0, "length": 421, "protein_name": "Medium-chain specific acyl-CoA dehydrogenase, mitochondrial", "gene_name": "ACADM", "organism": "Pig", "refseq_name": "medium-chain specific acyl-CoA dehydrogenase, mitochondrial precursor", "refseq_ac": "NP_999204", "gene_names_uniprotkb": "ACADM", "gene_names_refseq": "ACADM", "protein_names_uniprotkb": "Medium-chain specific acyl-CoA dehydrogenase, mitochondrial; 1.3.8.7; MCAD", "protein_names_refseq": "MCAD; acyl-CoA dehydrogenase, C-4 to C-12 straight chain; acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain; medium-chain acyl-CoA dehydrogenase; medium-chain specific acyl-CoA dehydrogenase, mitochondrial precursor; medium-chain specific acyl-CoA dehydrogenase, mitochondrial", "tax_id": 9823, "disease": "", "pathway": " (ssc:397104)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "12966080;16879370;19470521;3233192;32543654;8356049", "class_list": "", "function": "Investigation of ACADM in relation to fat deposition traits., [RefSeq, PubMed]; Investigation of structure of enzyme (from kidney) complexed with FAD analogs (e.g., 8-NH2-FAD) and acyl-CoA (e.g., octanoyl-CoA)., [RefSeq, PubMed]; Medium-chain specific acyl-CoA dehydrogenase is one of the acyl-CoA dehydrogenases that catalyze the first step of mitochondrial fatty acid beta-oxidation (FAO), breaking down fatty acids into acetyl-CoA and allowing the production of energy from fats (PubMed:3233192). The first step of FAO consists in the proR-proR stereospecific alpha, beta-dehydrogenation of fatty acyl-CoA thioesters using the electron transfer flavoprotein (ETF) as their physiologic electron acceptor, resulting in the formation of trans-2-enoyl-CoA ((2E)-enoyl-CoA) (PubMed:3233192). ETF is the electron acceptor that transfers electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) (By similarity). Among the different mitochondrial acyl-CoA dehydrogenases, medium-chain specific acyl-CoA dehydrogenase has preference for fatty acyl-CoAs with saturated 6 to 12 carbons long primary chains, making it but can also catalyze longer chains such as C14 and C16 (By similarity)., [UniProtKB, UniProtKB, PubMed, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q58XQ3", "ec_number_list": "", "go_molecular_function": "GO:0003995 acyl-CoA dehydrogenase activity;GO:0042802 identical protein binding;GO:0050660 flavin adenine dinucleotide binding;GO:0070991 medium-chain fatty acyl-CoA dehydrogenase activity", "go_cellular_component": "GO:0005759 mitochondrial matrix;GO:0030424 axon;GO:0031966 mitochondrial membrane;GO:0005737 cytoplasm", "go_biological_process": "GO:0006635 fatty acid beta-oxidation;GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase;GO:0019254 carnitine metabolic process, CoA-linked;GO:0045329 carnitine biosynthetic process;GO:0051793 medium-chain fatty acid catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P41367-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P00348-1", "uniprot_id": "HCDH_PIG", "mass": 34161.0, "length": 314, "protein_name": "Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial", "gene_name": "HADH", "organism": "Pig", "refseq_name": "hydroxyacyl-coenzyme A dehydrogenase, mitochondrial precursor", "refseq_ac": "NP_999496", "gene_names_uniprotkb": "HADH; HADHSC; HAD; SCHAD", "gene_names_refseq": "HADHSC; HADH; HAD", "protein_names_uniprotkb": "Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial; 1.1.1.35; HCDH; L-3-hydroxyacyl CoA dehydrogenase; Medium and short-chain L-3-hydroxyacyl-coenzyme A dehydrogenase; Short-chain 3-hydroxyacyl-CoA dehydrogenase", "protein_names_refseq": "HCDH; L-3-hydroxyacyl-CoA dehydrogenase; hydroxyacyl-coenzyme A dehydrogenase, mitochondrial precursor; hydroxyacyl-coenzyme A dehydrogenase, mitochondrial; medium and short-chain L-3-hydroxyacyl-coenzyme A dehydrogenase; short-chain 3-hydroxyacyl-CoA dehydrogenase", "tax_id": 9823, "disease": "", "pathway": " (ssc:397604); (R-SSC-77310); (R-SSC-77346); (R-SSC-77348); (R-SSC-77350); (R-SSC-77352); (R-SSC-9837999)", "pathway_count": 7, "publication_count": 7, "publication_id_list": "10064895;10548046;2817332;32543654;3479790;7409145;9593854", "class_list": "", "function": "Mitochondrial fatty acid beta-oxidation enzyme that catalyzes the third step of the beta-oxidation cycle for medium and short-chain 3-hydroxy fatty acyl-CoAs (C4 to C10) (PubMed:2817332, PubMed:9593854). Plays a role in the control of insulin secretion by inhibiting the activation of glutamate dehydrogenase 1 (GLUD1), an enzyme that has an important role in regulating amino acid-induced insulin secretion (By similarity). Plays a role in the maintenance of normal spermatogenesis through the reduction of fatty acid accumulation in the testes (By similarity)., [UniProtKB, UniProtKB, PubMed, PubMed, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9XS66", "ec_number_list": "", "go_molecular_function": "GO:0042802 identical protein binding;GO:0070403 NAD+ binding;GO:0003857 (3S)-3-hydroxyacyl-CoA dehydrogenase (NAD+) activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0006635 fatty acid beta-oxidation;GO:0007283 spermatogenesis;GO:0030154 cell differentiation;GO:0050796 regulation of insulin secretion;GO:0120162 positive regulation of cold-induced thermogenesis", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P00348-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q8WNV7-1", "uniprot_id": "DHRS4_PIG", "mass": 29919.0, "length": 279, "protein_name": "Dehydrogenase/reductase SDR family member 4", "gene_name": "DHRS4", "organism": "Pig", "refseq_name": "dehydrogenase/reductase SDR family member 4", "refseq_ac": "NP_999184", "gene_names_uniprotkb": "DHRS4", "gene_names_refseq": "DHRS4; PSCD; PerCR", "protein_names_uniprotkb": "Dehydrogenase/reductase SDR family member 4; 1.1.1.184; 1.1.1.300; CR; NADPH-dependent carbonyl reductase; NADPH-dependent retinol dehydrogenase/reductase; NDRD; PHCR; PSCD; PerCR; Peroxisomal carbonyl reductase; Peroxisomal short-chain alcohol dehydrogenase; Protein SDR25C2; Short chain dehydrogenase/reductase family 25C member 2", "protein_names_refseq": "CR; NADPH-dependent carbonyl reductase/NADP-retinol dehydrogenase; NADPH-dependent retinol dehydrogenase/reductase; NDRD; PHCR; carbonyl reductase/NADP-retinol dehydrogenase; dehydrogenase/reductase SDR family member 4; peroxisomal carbonyl reductase; peroxisomal short-chain alcohol dehydrogenase; short chain dehydrogenase/reductase family 25C member 2", "tax_id": 9823, "disease": "", "pathway": " (ssc:397082); (R-SSC-5365859); (R-SSC-9033241)", "pathway_count": 3, "publication_count": 6, "publication_id_list": "12604222;18334214;19056333;23036705;28489967;32543654", "class_list": "", "function": "NADPH-dependent oxidoreductase which catalyzes the reduction of a variety of compounds bearing carbonyl groups including ketosteroids, alpha-dicarbonyl compounds, aldehydes, aromatic ketones and quinones (PubMed:12604222, PubMed:19056333). Reduces all-trans-retinal and 9-cis retinal (Probable). Reduces 3-ketosteroids and benzil into 3alpha-hydroxysteroids and S-benzoin, respectively, in contrast to the stereoselectivity of primates DHRS4s which produce 3beta-hydroxysteroids and R-benzoin (PubMed:19056333). In the reverse reaction, catalyzes the NADP-dependent oxidation of 3alpha-hydroxysteroids and alcohol, but with much lower efficiency (PubMed:19056333). Involved in the metabolism of 3alpha-hydroxysteroids, retinoid, isatin and xenobiotic carbonyl compounds (PubMed:12604222, PubMed:19056333)., [UniProtKB, PubMed, PubMed]; Peroxisomal localization of tetrameric carbonyl reductase., [RefSeq, PubMed]; Studied the association of postmortem pH with SNPs in the fourth member of the short-chain dehydrogenase/reductase family (DHRS4), the first member of serpin peptidase inhibitor, clade G (complement inhibitor) (SERPING1), and the apolipoprotein R precursor (APOR) genes in Berkshire pigs. Results suggest that DHRS4, SERPING1, and APOR snps may be potential genetic markers for meat quality., [RefSeq, PubMed]; Sus scrofa DHRS4 gene is ortholog of human DHRS4 gene. These two genes have identical splicing phases, exon-intron structure and their coded proteins have identical catalytic amino-acid residues, Rossman fold consensus, Peroxisomal Targeting Signal consensus and the three amino-acid residues typical of vertebrate DHRS4 enzymes, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0042802 identical protein binding;GO:0052650 all-trans-retinol dehydrogenase (NADP+) activity;GO:0000253 3-beta-hydroxysteroid 3-dehydrogenase (NADP+) activity;GO:0004090 carbonyl reductase (NADPH) activity;GO:0016491 oxidoreductase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005777 peroxisome", "go_biological_process": "GO:0042180 ketone metabolic process;GO:0001523 retinoid metabolic process;GO:0042574 retinal metabolic process;GO:0008202 steroid metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q8WNV7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P00636-1", "uniprot_id": "F16P1_PIG", "mass": 36779.0, "length": 338, "protein_name": "Fructose-1,6-bisphosphatase 1", "gene_name": "FBP1", "organism": "Pig", "refseq_name": "fructose-1,6-bisphosphatase 1", "refseq_ac": "NP_999144", "gene_names_uniprotkb": "FBP1; FBP", "gene_names_refseq": "FBP1; FBP", "protein_names_uniprotkb": "Fructose-1,6-bisphosphatase 1; 3.1.3.11; D-fructose-1,6-bisphosphate 1-phosphohydrolase 1; FBPase 1; Liver FBPase", "protein_names_refseq": "D-fructose-1,6-bisphosphate 1-phosphohydrolase 1; FBPase 1; fructose 1,6-bisphosphatase; fructose-1,6-bisphosphatase 1; liver FBPase", "tax_id": 9823, "disease": "", "pathway": " (ssc:397038); (R-SSC-70263)", "pathway_count": 2, "publication_count": 20, "publication_id_list": "10913263;12595528;1312721;1313579;14530289;14978036;15767255;16200456;17933867;1849642;2157849;2164670;23844654;24436333;30683805;32543654;6277165;6291465;6296821;9708979", "class_list": "", "function": "Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations, acting as a rate-limiting enzyme in gluconeogenesis. Plays a role in regulating glucose sensing and insulin secretion of pancreatic beta-cells. Appears to modulate glycerol gluconeogenesis in liver. Important regulator of appetite and adiposity; increased expression of the protein in liver after nutrient excess increases circulating satiety hormones and reduces appetite-stimulating neuropeptides and thus seems to provide a feedback mechanism to limit weight gain., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Directed mutations, kinetics, and structure determinations link the central cavity of FBP to AMP/fructose 2,6-bisphosphate synergism., [RefSeq, PubMed]; Each subunit in the wild-type tetramer can independently achieve maximum velocity when activated by Mg(2+); findings are fully consistent with a mechanism of cooperativity that arises from within a single subunit of fructose-1,6-bisphosphatase., [RefSeq, PubMed]; Fructose-1,6-bisphosphatase mutations in the AMP-binding site (K112A and Y113A) demonstrated an eight to nine-fold decrease in AMP inhibition. Publication Status: Online-Only, [RefSeq, PubMed]; The AMP/Mg(2+) and AMP/Zn(2+) complexes of Asp(10) FBPase are in intermediate quaternary conformations., [RefSeq, PubMed]; The primary structures of muscle FBPases , showed on their molecular surface a number of domains specific for proteins transported into the nucleus., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity;GO:0042802 identical protein binding;GO:0046872 metal ion binding;GO:0016208 AMP binding;GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0046580 negative regulation of Ras protein signal transduction;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0071466 cellular response to xenobiotic stimulus;GO:0006094 gluconeogenesis;GO:0030308 negative regulation of cell growth", "synthesized_glycan_count": 0, "hit_score": 2.1, "record_id": "P00636-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P11708-1", "uniprot_id": "MDHC_PIG", "mass": 36454.0, "length": 334, "protein_name": "Malate dehydrogenase, cytoplasmic", "gene_name": "MDH1", "organism": "Pig", "refseq_name": "malate dehydrogenase, cytoplasmic", "refseq_ac": "NP_999039", "gene_names_uniprotkb": "MDH1", "gene_names_refseq": "KAR; MDH1; MDH", "protein_names_uniprotkb": "Malate dehydrogenase, cytoplasmic; 1.1.1.37; Aromatic alpha-keto acid reductase; Cytosolic malate dehydrogenase; KAR", "protein_names_refseq": "aromatic alpha-keto acid reductase; cytosolic malate dehydrogenase; malate dehydrogenase 1, NAD (soluble); malate dehydrogenase, cytoplasmic", "tax_id": 9823, "disease": "", "pathway": " (ssc:396894); (R-SSC-9856872)", "pathway_count": 2, "publication_count": 8, "publication_id_list": "10075524;19015805;21152271;2775751;32543654;3312200;3606987;8682322", "class_list": "", "function": "Both immunofluorescence and immunoelectron microscopy demonstrated cMDH at the plasma membrane of LLC-PK(1) cells., [RefSeq, PubMed]; Catalyzes the reduction of aromatic alpha-keto acids in the presence of NADH. Plays essential roles in the malate-aspartate shuttle and the tricarboxylic acid cycle, important in mitochondrial NADH supply for oxidative phosphorylation. Catalyzes the reduction of 2-oxoglutarate to 2-hydroxyglutarate, leading to elevated reactive oxygen species (ROS)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Structural features of the alphaB-crystallin oligomer when complexed with target proteins under mild stress conditions, i.e., reduction of alpha-lactalbumin at 37 degrees C and malate dehydrogenase when heated at 42 degrees C, were investigated. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q29560", "ec_number_list": "", "go_molecular_function": "GO:0051287 NAD binding;GO:0030060 L-malate dehydrogenase (NAD+) activity;GO:0047995 (2R)-hydroxyphenylpyruvate reductase [NAD(P)H] activity;GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;GO:0016615 malate dehydrogenase activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0006099 tricarboxylic acid cycle;GO:0006107 oxaloacetate metabolic process;GO:0019674 NAD+ metabolic process;GO:0006108 malate metabolic process;GO:0006739 NADP+ metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P11708-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q0QF01-1", "uniprot_id": "SDHA_PIG", "mass": 72832.0, "length": 664, "protein_name": "Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial", "gene_name": "SDHA", "organism": "Pig", "refseq_name": "succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial isoform 2", "refseq_ac": "XP_020932590", "gene_names_uniprotkb": "SDHA", "gene_names_refseq": "Fp; SDHA", "protein_names_uniprotkb": "Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; 1.1.5.-; 1.3.5.1; Flavoprotein subunit of complex II; Fp; Malate dehydrogenase [quinone] flavoprotein subunit", "protein_names_refseq": "Flavoprotein subunit of complex II; malate dehydrogenase [quinone] flavoprotein subunit; mitochondrial succinate dehydrogenase complex subunit A; succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial isoform 2; succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; succinate dehydrogenase complex subunit A flavoprotein; succinate dehydrogenase complex, subunit A, flavoprotein (Fp)", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-71403); (R-SSC-9854311)", "pathway_count": 2, "publication_count": 5, "publication_id_list": "15989954;16751257;17480203;17697375;32543654", "class_list": "", "function": "Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, PubMed, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0SNV1", "ec_number_list": "", "go_molecular_function": "GO:0009055 electron transfer activity;GO:0050660 flavin adenine dinucleotide binding;GO:0008177 succinate dehydrogenase (quinone) activity", "go_cellular_component": "GO:0005743 mitochondrial inner membrane;GO:0005759 mitochondrial matrix;GO:0045273 respiratory chain complex II (succinate dehydrogenase)", "go_biological_process": "GO:0006099 tricarboxylic acid cycle;GO:0007399 nervous system development;GO:0006105 succinate metabolic process;GO:0006121 mitochondrial electron transport, succinate to ubiquinone;GO:0022900 electron transport chain", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q0QF01-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P28839-1", "uniprot_id": "AMPL_PIG", "mass": 56047.0, "length": 519, "protein_name": "Cytosol aminopeptidase", "gene_name": "LAP3", "organism": "Pig", "refseq_name": "cytosol aminopeptidase", "refseq_ac": "XP_003356918", "gene_names_uniprotkb": "LAP3", "gene_names_refseq": "LAP-3; LAP3", "protein_names_uniprotkb": "Cytosol aminopeptidase; 3.4.11.1; 3.4.11.5; 3.4.13.23; Cysteinylglycine-S-conjugate dipeptidase; LAP-3; Leucine aminopeptidase 3; Leucyl aminopeptidase; Proline aminopeptidase; Prolyl aminopeptidase", "protein_names_refseq": "Leucyl aminopeptidase; Proline aminopeptidase; Prolyl aminopeptidase; cysteinylglycine-S-conjugate dipeptidase; cytosol aminopeptidase", "tax_id": 9823, "disease": "", "pathway": " (ssc:100739583)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "1908238;32543654", "class_list": "", "function": "Cytosolic metallopeptidase that catalyzes the removal of unsubstituted N-terminal hydrophobic amino acids from various peptides. The presence of Zn(2+) ions is essential for the peptidase activity, and the association with other cofactors can modulate the substrate spectificity of the enzyme. For instance, in the presence of Mn(2+), it displays a specific Cys-Gly hydrolyzing activity of Cys-Gly-S-conjugates. Involved in the metabolism of glutathione and in the degradation of glutathione S-conjugates, which may play a role in the control of the cell redox status., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "I3LD43", "ec_number_list": "", "go_molecular_function": "GO:0030145 manganese ion binding;GO:0004180 carboxypeptidase activity;GO:0070006 metalloaminopeptidase activity;GO:0008233 peptidase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0006508 proteolysis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "P28839-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0A5G2QD80-1", "uniprot_id": "DCTN2_PIG", "mass": 44650.0, "length": 405, "protein_name": "Dynactin subunit 2", "gene_name": "DCTN2", "organism": "Pig", "refseq_name": "dynactin subunit 2 isoform 2", "refseq_ac": "XP_020947539", "gene_names_uniprotkb": "DCTN2", "gene_names_refseq": "DCTN2", "protein_names_uniprotkb": "Dynactin subunit 2", "protein_names_refseq": "dynactin 2 (p50); dynactin subunit 2 isoform 2", "tax_id": 9823, "disease": "", "pathway": " (ssc:100515661); (R-SSC-2132295); (R-SSC-2565942); (R-SSC-3371497); (R-SSC-380259); (R-SSC-380270); (R-SSC-380284); (R-SSC-380320); (R-SSC-5620912); (R-SSC-6807878); (R-SSC-8854518)", "pathway_count": 11, "publication_count": 5, "publication_id_list": "25814576;29420470;32543654;33734450;36071160", "class_list": "", "function": "Part of the dynactin complex that activates the molecular motor dynein for ultra-processive transport along microtubules. In the dynactin soulder domain, binds the ACTR1A filament and acts as a molecular ruler to determine the length (PubMed:25814576, PubMed:29420470, PubMed:33734450, PubMed:36071160). Modulates cytoplasmic dynein binding to an organelle, and plays a role in prometaphase chromosome alignment and spindle organization during mitosis. Involved in anchoring microtubules to centrosomes. May play a role in synapse formation during brain development (By similarity)., [UniProtKB, PubMed, PubMed, UniProtKB, PubMed, PubMed, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A4X1W6J2;F1SKF9", "ec_number_list": "", "go_molecular_function": "GO:0019901 protein kinase binding;GO:0042802 identical protein binding;GO:0030507 spectrin binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005813 centrosome;GO:0005874 microtubule;GO:0016020 membrane;GO:0005869 dynactin complex", "go_biological_process": "GO:0007052 mitotic spindle organization;GO:0007017 microtubule-based process;GO:0007080 mitotic metaphase chromosome alignment", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "A0A5G2QD80-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q28989-1", "uniprot_id": "AMBN_PIG", "mass": 44927.0, "length": 421, "protein_name": "Ameloblastin", "gene_name": "AMBN", "organism": "Pig", "refseq_name": "ameloblastin precursor", "refseq_ac": "NP_999202", "gene_names_uniprotkb": "AMBN", "gene_names_refseq": "AMBN", "protein_names_uniprotkb": "Ameloblastin; Sheathlin", "protein_names_refseq": "ameloblastin precursor; sheathlin", "tax_id": 9823, "disease": "", "pathway": " (ssc:397102); (R-SSC-381426); (R-SSC-8957275)", "pathway_count": 3, "publication_count": 3, "publication_id_list": "17890672;32543654;9062558", "class_list": "", "function": "Involved in the mineralization and structural organization of enamel., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 1, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008083 growth factor activity;GO:0030345 structural constituent of tooth enamel", "go_cellular_component": "", "go_biological_process": "GO:0007155 cell adhesion;GO:0042475 odontogenesis of dentin-containing tooth;GO:0031214 biomineral tissue development", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q28989-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q29551-1", "uniprot_id": "SCOT1_PIG", "mass": 56338.0, "length": 520, "protein_name": "Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial", "gene_name": "OXCT1", "organism": "Pig", "refseq_name": "succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial precursor", "refseq_ac": "NP_999103", "gene_names_uniprotkb": "OXCT1; OXCT; SCOT", "gene_names_refseq": "OXCT1; OXCT; SCOT", "protein_names_uniprotkb": "Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial; 2.8.3.5; 3-oxoacid CoA-transferase 1; SCOT-s; SCOT; Somatic-type succinyl-CoA:3-oxoacid CoA-transferase; Succinate-coenzyme A transferase; Succinyl-CoA:3-oxoacid CoA transferase", "protein_names_refseq": "SCOT-s; somatic-type succinyl-CoA:3-oxoacid CoA-transferase; succinate-coenzyme A transferase; succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial precursor; succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial; succinyl-CoA:3-oxoacid CoA transferase; succinyl-CoA:alpha-ketoacid coenzyme A transferase", "tax_id": 9823, "disease": "", "pathway": " (ssc:396978); (R-SSC-77108); (R-SSC-9837999)", "pathway_count": 3, "publication_count": 9, "publication_id_list": "11327867;12463743;15388917;1730685;17718512;20606260;20977214;32543654;7915164", "class_list": "", "function": "Key enzyme for ketone body catabolism (By similarity). Catalyzes the first, rate-limiting step of ketone body utilization in extrahepatic tissues, by transferring coenzyme A (CoA) from a donor thiolester species (succinyl-CoA) to an acceptor carboxylate (acetoacetate), and produces acetoacetyl-CoA. Acetoacetyl-CoA is further metabolized by acetoacetyl-CoA thiolase into two acetyl-CoA molecules which enter the citric acid cycle for energy production (Probable) (PubMed:11327867, PubMed:17718512). Forms a dimeric enzyme where both of the subunits are able to form enzyme-CoA thiolester intermediates, but only one subunit is competent to transfer the CoA moiety to the acceptor carboxylate (3-oxo acid) and produce a new acyl-CoA (PubMed:11327867). Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate (PubMed:17718512)., [UniProtKB, PubMed, PubMed, UniProtKB, PubMed]; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Mechanism of SCOT catalysis, [RefSeq, PubMed]; On the basis of these results the conformational change in SCOT was deduced to be a domain rotation of 17 degrees coupled with movement of two loops: res. 321-329 that interact with succinate or acetoacetate and res. 374-386 that interact with CoA., [RefSeq, PubMed]; Structure of the CoA transferase from pig heart to 1.7 A resolution, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 3, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "F1SMH7", "ec_number_list": "", "go_molecular_function": "GO:0042803 protein homodimerization activity;GO:0008260 succinyl-CoA:3-oxo-acid CoA-transferase activity;GO:0008410 CoA-transferase activity", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0046952 ketone body catabolic process;GO:1902224 ketone body metabolic process", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "Q29551-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q28960-1", "uniprot_id": "CBR1_PIG", "mass": 31693.0, "length": 289, "protein_name": "Carbonyl reductase [NADPH] 1", "gene_name": "CBR1", "organism": "Pig", "refseq_name": "carbonyl reductase [NADPH] 1", "refseq_ac": "NP_999238", "gene_names_uniprotkb": "CBR1; CBR; CRN", "gene_names_refseq": "CBR1; PG-9-KR", "protein_names_uniprotkb": "Carbonyl reductase [NADPH] 1; 1.1.1.184; 1.1.1.189; 1.1.1.196; 1.1.1.197; 1.1.1.71; 15-hydroxyprostaglandin dehydrogenase [NADP(+)]; 20-beta-hydroxysteroid dehydrogenase; Alcohol dehydrogenase [NAD(P)+] CBR1; NADPH-dependent carbonyl reductase 1; PG-9-KR; Prostaglandin 9-ketoreductase; Prostaglandin-E(2) 9-reductase", "protein_names_refseq": "15-hydroxyprostaglandin dehydrogenase; 20-beta-hydroxysteroid dehydrogenase; NADPH-dependent carbonyl reductase 1; alcohol dehydrogenase [NAD(P)+] CBR1; carbonyl reductase [NADPH] 1; prostaglandin 9-ketoreductase; prostaglandin-E(2) 9-reductase", "tax_id": 9823, "disease": "", "pathway": " (ssc:397143)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "11279087;1377683;15145449;1597188;28681587;32543654", "class_list": "", "function": "NADPH-dependent reductase with broad substrate specificity. Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics. Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol. Can convert prostaglandin E2 to prostaglandin F2-alpha (PubMed:1377683, PubMed:1597188). Can bind glutathione, which explains its higher affinity for glutathione-conjugated substrates. Catalyzes the reduction of S-nitrosoglutathione. In addition, participates in the glucocorticoid metabolism by catalyzing the NADPH-dependent cortisol/corticosterone into 20beta-dihydrocortisol (20b-DHF) or 20beta-corticosterone (20b-DHB), which are weak agonists of NR3C1 and NR3C2 in adipose tissue (By similarity)., [UniProtKB, UniProtKB, PubMed, PubMed]; NF-kappaB (p65) could bind to the special element of CBR1 gene promoter in porcine endometrial epithelial cells in vitro, [RefSeq, PubMed]; Two Cys residues, Cys 149 and Cys 226, are involved in the enzyme activity; Cys 226 is involved in binding of the cofactor NADPH., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0047020 15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity;GO:0004090 carbonyl reductase (NADPH) activity;GO:0047021 15-hydroxyprostaglandin dehydrogenase (NADP+) activity;GO:0050221 prostaglandin E2 9-reductase activity;GO:0160163 S-nitrosoglutathione reductase (NADPH) activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0006629 lipid metabolic process;GO:0006805 xenobiotic metabolic process;GO:0042373 vitamin K metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q28960-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q95250-1", "uniprot_id": "PGRC1_PIG", "mass": 21609.0, "length": 194, "protein_name": "Membrane-associated progesterone receptor component 1", "gene_name": "PGRMC1", "organism": "Pig", "refseq_name": "membrane-associated progesterone receptor component 1", "refseq_ac": "NP_999076", "gene_names_uniprotkb": "PGRMC1; PGRMC", "gene_names_refseq": "PGRMC1; mPR", "protein_names_uniprotkb": "Membrane-associated progesterone receptor component 1; mPR", "protein_names_refseq": "membrane-associated progesterone receptor component 1; steroid membrane binding protein", "tax_id": 9823, "disease": "", "pathway": " (ssc:396946); (R-SSC-6798695)", "pathway_count": 2, "publication_count": 4, "publication_id_list": "28644880;32543654;8774719;8954087", "class_list": "", "function": "Component of a progesterone-binding protein complex. Binds progesterone (By similarity). Has many reported cellular functions (heme homeostasis, interaction with CYPs). Required for the maintenance of uterine histoarchitecture and normal female reproductive lifespan (By similarity). Intracellular heme chaperone. Regulates heme synthesis via interactions with FECH and acts as a heme donor for at least some hemoproteins (By similarity). Forms a ternary complex with TMEM97 receptor and low density lipid receptor/LDLR, which increases LDLR-mediated LDL lipoprotein internalization (By similarity)., [UniProtKB, UniProtKB, UniProtKB]; Component of a progesterone-binding protein complex. Binds progesterone. Has many reported cellular functions (heme homeostasis, interaction with CYPs). Required for the maintenance of uterine histoarchitecture and normal female reproductive lifespan. Intracellular heme chaperone. Regulates heme synthesis via interactions with FECH and acts as a heme donor for at least some hemoproteins. Forms a ternary complex with TMEM97 receptor and low density lipid receptor/LDLR, which increases LDLR-mediated LDL lipoprotein internalization., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0042803 protein homodimerization activity;GO:0046872 metal ion binding;GO:0005496 steroid binding;GO:0020037 heme binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0005741 mitochondrial outer membrane;GO:0005783 endoplasmic reticulum;GO:0016020 membrane;GO:0012505 endomembrane system", "go_biological_process": "GO:1903078 positive regulation of protein localization to plasma membrane;GO:0006783 heme biosynthetic process;GO:0140077 positive regulation of lipoprotein transport", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q95250-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q95333-1", "uniprot_id": "XPP2_PIG", "mass": 75756.0, "length": 673, "protein_name": "Xaa-Pro aminopeptidase 2", "gene_name": "XPNPEP2", "organism": "Pig", "refseq_name": "xaa-Pro aminopeptidase 2 precursor", "refseq_ac": "NP_001004048", "gene_names_uniprotkb": "XPNPEP2", "gene_names_refseq": "XPNPEP2", "protein_names_uniprotkb": "Xaa-Pro aminopeptidase 2; 3.4.11.9; Aminoacylproline aminopeptidase; Membrane-bound APP; Membrane-bound AmP; Membrane-bound aminopeptidase P; X-Pro aminopeptidase 2; mAmP", "protein_names_refseq": "X-Pro aminopeptidase 2; aminoacylproline aminopeptidase; aminopeptidase P; mAmP; membrane-bound APP; membrane-bound AmP; membrane-bound aminopeptidase P; xaa-Pro aminopeptidase 2 precursor; xaa-Pro aminopeptidase 2", "tax_id": 9823, "disease": "", "pathway": " (ssc:445538)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "1312513;32543654;7744038;8870669", "class_list": "", "function": "Membrane-bound metalloprotease which catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides, such as Arg-Pro-Pro. May play a role in the metabolism of the vasodilator bradykinin., [UniProtKB, PubMed, PubMed, PubMed, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 6, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 6, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 6, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 6, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0046872 metal ion binding;GO:0070006 metalloaminopeptidase activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0070062 extracellular exosome;GO:0098552 side of membrane", "go_biological_process": "GO:0006508 proteolysis", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "Q95333-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2YGT9-1", "uniprot_id": "RL6_PIG", "mass": 32190.0, "length": 284, "protein_name": "Large ribosomal subunit protein eL6", "gene_name": "RPL6", "organism": "Pig", "refseq_name": "large ribosomal subunit protein eL6", "refseq_ac": "NP_001038007", "gene_names_uniprotkb": "RPL6", "gene_names_refseq": "RPL6", "protein_names_uniprotkb": "Large ribosomal subunit protein eL6; 60S ribosomal protein L6", "protein_names_refseq": "60S ribosomal protein L6; large ribosomal subunit protein eL6; ribosome protein L6; tax-responsive enhancer element-binding protein 107", "tax_id": 9823, "disease": "", "pathway": " (ssc:733592)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "24930395;32543654", "class_list": "", "function": "Component of the large ribosomal subunit (PubMed:24930395). The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:24930395)., [UniProtKB, PubMed]; Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005634 nucleus;GO:0014069 postsynaptic density;GO:0036464 cytoplasmic ribonucleoprotein granule;GO:0098556 cytoplasmic side of rough endoplasmic reticulum membrane;GO:0022625 cytosolic large ribosomal subunit", "go_biological_process": "GO:0002181 cytoplasmic translation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q2YGT9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P11607-1", "uniprot_id": "AT2A2_PIG", "mass": 114792.0, "length": 1042, "protein_name": "Sarcoplasmic/endoplasmic reticulum calcium ATPase 2", "gene_name": "ATP2A2", "organism": "Pig", "refseq_name": "sarcoplasmic/endoplasmic reticulum calcium ATPase 2", "refseq_ac": "NP_999030", "gene_names_uniprotkb": "ATP2A2", "gene_names_refseq": "ATP2A2; ATP2; SERCA2", "protein_names_uniprotkb": "Sarcoplasmic/endoplasmic reticulum calcium ATPase 2; 7.2.2.10; Calcium pump 2; Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform; Endoplasmic reticulum class 1/2 Ca(2+) ATPase; SERCA2; SR Ca(2+)-ATPase 2", "protein_names_refseq": "Ca(2+)-transport ATPase class 3; SR Ca(2+)-ATPase 2; calcium pump 2; endoplasmic reticulum class 1/2 Ca(2+) ATPase; sarcoplasmic/endoplasmic reticulum calcium ATPase 2; sarcoplasmic/endoplasmic-reticulum Ca(2+) pump gene 2", "tax_id": 9823, "disease": "", "pathway": " (ssc:396875); (R-SSC-418359); (R-SSC-5578775); (R-SSC-936837)", "pathway_count": 4, "publication_count": 8, "publication_id_list": "18043064;18342232;2015309;21152695;2158303;2527496;30777856;32543654", "class_list": "", "function": "Catalyzes the hydrolysis of ATP coupled with the transport of calcium., [UniProtKB, UniProtKB, UniProtKB]; Data suggest that the beneficial effects of SERCA2a gene transfer may involve the attenuation of ER stress-associated myocardial apoptosis., [RefSeq, PubMed]; Involved in the regulation of the contraction/relaxation cycle. Acts as a regulator of TNFSF11-mediated Ca(2+) signaling pathways via its interaction with TMEM64 which is critical for the TNFSF11-induced CREB1 activation and mitochondrial ROS generation necessary for proper osteoclast generation. Association between TMEM64 and SERCA2 in the ER leads to cytosolic Ca(2+) spiking for activation of NFATC1 and production of mitochondrial ROS, thereby triggering Ca(2+) signaling cascades that promote osteoclast differentiation and activation., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Molecular dynamics simulations predict that isoform-specific residues support distinct intramolecular interactions in SERCA2a and SERCA1a, [RefSeq, PubMed]; Overexpression of SERCA2a by in vivo rAAV1-mediated intracoronary gene transfer preserved systolic function, potentially prevented diastolic dysfunction, and improved ventricular remodeling., [RefSeq, PubMed]; Oxidative/nitrosative stress associated with lung resection influences SERCA2a activity independent of any influence on protein expression or phospholamban phosphorylation., [RefSeq, PubMed]; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen. Involved in autophagy in response to starvation. Upon interaction with VMP1 and activation, controls ER-isolation membrane contacts for autophagosome formation. Also modulates ER contacts with lipid droplets, mitochondria and endosomes (By similarity). In coordination with FLVCR2 mediates heme-stimulated switching from mitochondrial ATP synthesis to thermogenesis (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "P11606;P79426;P79427", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0019899 enzyme binding;GO:0005246 calcium channel regulator activity;GO:0016887 ATP hydrolysis activity;GO:0044325 transmembrane transporter binding", "go_cellular_component": "GO:0016020 membrane;GO:0033017 sarcoplasmic reticulum membrane;GO:0097470 ribbon synapse", "go_biological_process": "GO:0000045 autophagosome assembly;GO:0006874 intracellular calcium ion homeostasis;GO:0070588 calcium ion transmembrane transport;GO:0010882 regulation of cardiac muscle contraction by calcium ion signaling;GO:0032470 positive regulation of endoplasmic reticulum calcium ion concentration", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P11607-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P36968-1", "uniprot_id": "GPX4_PIG", "mass": 22337.0, "length": 197, "protein_name": "Phospholipid hydroperoxide glutathione peroxidase", "gene_name": "GPX4", "organism": "Pig", "refseq_name": "phospholipid hydroperoxide glutathione peroxidase precursor", "refseq_ac": "NP_999572", "gene_names_uniprotkb": "GPX4", "gene_names_refseq": "GPX4; PHGPx", "protein_names_uniprotkb": "Phospholipid hydroperoxide glutathione peroxidase; 1.11.1.12; 1.11.1.9; GPx-4; GSHPx-4; Glutathione peroxidase 4; PHGPx", "protein_names_refseq": "GPx-4; GSHPx-4; Phospholipid hydroperoxide glutathione peroxidase, mitochondrial; glutathione peroxidase 4 (phospholipid hydroperoxidase); phospholipid hydroperoxide glutathione peroxidase precursor", "tax_id": 9823, "disease": "", "pathway": " (ssc:399537); (R-SSC-2142712); (R-SSC-2142770); (R-SSC-9018676); (R-SSC-9018896); (R-SSC-9020265); (R-SSC-9023661)", "pathway_count": 7, "publication_count": 8, "publication_id_list": "1778506;2386798;32543654;3978121;8125951;8135530;8323565;8617728", "class_list": "", "function": "Essential antioxidant peroxidase that directly reduces phospholipid hydroperoxide even if they are incorporated in membranes and lipoproteins (PubMed:2386798, PubMed:3978121, PubMed:8135530). Can also reduce fatty acid hydroperoxide, cholesterol hydroperoxide and thymine hydroperoxide (PubMed:2386798, PubMed:3978121, PubMed:8135530). Plays a key role in protecting cells from oxidative damage by preventing membrane lipid peroxidation (By similarity). Required to prevent cells from ferroptosis, a non-apoptotic cell death resulting from an iron-dependent accumulation of lipid reactive oxygen species (By similarity). The presence of selenocysteine (Sec) versus Cys at the active site is essential for life: it provides resistance to overoxidation and prevents cells against ferroptosis (By similarity). The presence of Sec at the active site is also essential for the survival of a specific type of parvalbumin-positive interneurons, thereby preventing against fatal epileptic seizures (By similarity). May be required to protect cells from the toxicity of ingested lipid hydroperoxides (By similarity). Required for normal sperm development and male fertility (By similarity). Essential for maturation and survival of photoreceptor cells (By similarity). Plays a role in a primary T-cell response to viral and parasitic infection by protecting T-cells from ferroptosis and by supporting T-cell expansion (By similarity). Plays a role of glutathione peroxidase in platelets in the arachidonic acid metabolism (By similarity). Reduces hydroperoxy ester lipids formed by a 15-lipoxygenase that may play a role as down-regulator of the cellular 15-lipoxygenase pathway (PubMed:8617728). Can also reduce small soluble hydroperoxides such as H2O2, cumene hydroperoxide and tert-butyl hydroperoxide (PubMed:3978121)., [UniProtKB, PubMed, UniProtKB, PubMed, UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004602 glutathione peroxidase activity;GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity;GO:0042802 identical protein binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005739 mitochondrion;GO:0005829 cytosol;GO:0005635 nuclear envelope;GO:0032991 protein-containing complex", "go_biological_process": "GO:0006979 response to oxidative stress;GO:0007283 spermatogenesis;GO:0034599 cellular response to oxidative stress;GO:0019372 lipoxygenase pathway;GO:0019369 arachidonate metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P36968-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P10173-1", "uniprot_id": "FUMH_PIG", "mass": 54749.0, "length": 512, "protein_name": "Fumarate hydratase, mitochondrial", "gene_name": "FH", "organism": "Pig", "refseq_name": "fumarate hydratase, mitochondrial", "refseq_ac": "NP_001230517", "gene_names_uniprotkb": "FH", "gene_names_refseq": "FH; Fumarase", "protein_names_uniprotkb": "Fumarate hydratase, mitochondrial; 4.2.1.2; Fumarase", "protein_names_refseq": "fumarate hydratase, mitochondrial", "tax_id": 9823, "disease": "", "pathway": " (ssc:100627128)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "21498518;32543654;3377794", "class_list": "", "function": "Catalyzes the dehydration of L-malate to fumarate. Fumarate metabolism in the cytosol plays a role during urea cycle and arginine metabolism; fumarate being a by-product of the urea cycle and amino-acid catabolism. Also plays a role in DNA repair by promoting non-homologous end-joining (NHEJ). In response to DNA damage and phosphorylation by PRKDC, translocates to the nucleus and accumulates at DNA double-strand breaks (DSBs): acts by catalyzing formation of fumarate, an inhibitor of KDM2B histone demethylase activity, resulting in enhanced dimethylation of histone H3 'Lys-36' (H3K36me2)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Catalyzes the hydration of fumarate to L-malate in the tricarboxylic acid (TCA) cycle to facilitate a transition step in the production of energy in the form of NADH., [UniProtKB, UniProtKB, UniProtKB, PubMed]; Catalyzes the reversible stereospecific interconversion of fumarate to L-malate (PubMed:21498518). Experiments in different species have demonstrated that specific isoforms of this protein act in defined pathways and favor one direction over the other (Probable)., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A287AR55", "ec_number_list": "", "go_molecular_function": "GO:0004333 fumarate hydratase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005739 mitochondrion;GO:0005829 cytosol;GO:0005694 chromosome", "go_biological_process": "GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining;GO:0006106 fumarate metabolic process;GO:0006099 tricarboxylic acid cycle;GO:0006281 DNA repair;GO:0006974 DNA damage response", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "P10173-1", "record_type": "protein" }, { "uniprot_canonical_ac": "O97939-1", "uniprot_id": "ENAM_PIG", "mass": 128352.0, "length": 1142, "protein_name": "Enamelin", "gene_name": "ENAM", "organism": "Pig", "refseq_name": "enamelin precursor", "refseq_ac": "NP_999406", "gene_names_uniprotkb": "ENAM", "gene_names_refseq": "ENAM", "protein_names_uniprotkb": "Enamelin", "protein_names_refseq": "enamelin precursor", "tax_id": 9823, "disease": "", "pathway": " (ssc:397473)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "18508280;19263522;9206327;9372788", "class_list": "", "function": "Conformational change from alpha-helix to beta-sheet with increasing concentration of calcium ions, [RefSeq, PubMed]; Involved in the mineralization and structural organization of enamel. Involved in the extension of enamel during the secretory stage of dental enamel formation., [UniProtKB, PubMed]; Results demonstrate that the 32 kDa enamelin has a direct interaction with amelogenin in vitro., [RefSeq, PubMed]", "predicted_glycosites": 6, "predicted_n_glycosites": 4, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 3, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 3, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 3, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 9, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0030345 structural constituent of tooth enamel", "go_cellular_component": "GO:0031012 extracellular matrix", "go_biological_process": "GO:0031214 biomineral tissue development;GO:0070175 positive regulation of enamel mineralization;GO:0097186 amelogenesis;GO:0036305 ameloblast differentiation", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "O97939-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P00346-1", "uniprot_id": "MDHM_PIG", "mass": 35596.0, "length": 338, "protein_name": "Malate dehydrogenase, mitochondrial", "gene_name": "MDH2", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "MDH2", "gene_names_refseq": "", "protein_names_uniprotkb": "Malate dehydrogenase, mitochondrial; 1.1.1.37", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 4, "publication_id_list": "3038184;6959107;8117664;8672129", "class_list": "", "function": "Mitochondrial malate dehydrogenase that catalyzes the reversible conversion of malate to oxaloacetate using NAD(+) as a cofactor. Plays a central role in the tricarboxylic acid (TCA) cycle contributing to cellular respiration and energy production via the mitochondrial electron transport chain (By similarity). Also participates in the malate-aspartate NADH shuttle, facilitating transfer of reducing equivalents between cytosol and mitochondria to maintain redox balance (NAD(+)/NADH homeostasis) and support metabolic flux between compartments (By similarity). In addition to its metabolic role, binds to RNA in cells, associating with cytosolic RNAs including tRNAs and mRNAs (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q95308", "ec_number_list": "", "go_molecular_function": "GO:0042803 protein homodimerization activity;GO:0051087 protein-folding chaperone binding;GO:0030060 L-malate dehydrogenase (NAD+) activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0006099 tricarboxylic acid cycle;GO:0009060 aerobic respiration;GO:0006108 malate metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P00346-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P00592-1", "uniprot_id": "PA21B_PIG", "mass": 16279.0, "length": 146, "protein_name": "Phospholipase A2, major isoenzyme", "gene_name": "PLA2G1B", "organism": "Pig", "refseq_name": "phospholipase A2, major isoenzyme precursor", "refseq_ac": "NP_001004037", "gene_names_uniprotkb": "PLA2G1B", "gene_names_refseq": "PLA2G1B; PLA2; sPLA(2)-IB", "protein_names_uniprotkb": "Phospholipase A2, major isoenzyme; 3.1.1.4; Group IB phospholipase A2; Phosphatidylcholine 2-acylhydrolase 1B", "protein_names_refseq": "group IB phospholipase A2; group IB secretory phospholipase A(2); phosphatidylcholine 2-acylhydrolase 1B; phospholipase A2, group IB (pancreas); phospholipase A2, major isoenzyme precursor; phospholipase A2, major isoenzyme", "tax_id": 9823, "disease": "", "pathway": " (ssc:445525)", "pathway_count": 1, "publication_count": 20, "publication_id_list": "1718309;17603006;18260608;18468626;19301847;2007145;2215698;2254938;2498336;26117657;30120882;3028739;3295782;4919729;5528841;6876174;7556053;7664098;7703697;884127", "class_list": "", "function": "An increased sPLA(2) activity and a reduced inhibition may play an important role in the pathogenesis of ischemia-reperfusion injury of non-heart-beating donor liver grafts., [RefSeq, PubMed]; Equilibrium unfolding of porcine pancreatic phospholipase A2 was monitored using multiple approaches. An unusually broad unfolding transition at remarkably high denaturant concentration was observed., [RefSeq, PubMed]; In this study, the inhibitory activity of 1-napthaleneacetic acid (NAA) against porcine pancreatic PLA2 has been explained through isothermal titration calorimetry and enzyme kinetics studies., [RefSeq, PubMed]; Interfacial activation of pig pancreatic IB phospholipase A(2) (PLA2) is modeled in terms of the three discrete premicellar complexes (E(i)(#), i = 1, 2, or 3) consecutively formed by the cooperative binding of a monodisperse amphiphile to the i-face, [RefSeq, PubMed]; Results show that the decylsulfate epitope for the successive E i (#) complexes increasingly resembles the micellar complex formed by the binding of PLA2 to preformed micelles., [RefSeq, PubMed]; Secretory calcium-dependent phospholipase A2 that primarily targets dietary phospholipids in the intestinal tract (PubMed:17603006). Hydrolyzes the ester bond of the fatty acyl group attached at sn-2 position of phospholipids (phospholipase A2 activity) with preference for phosphatidylethanolamines and phosphatidylglycerols over phosphatidylcholines (By similarity). May play a role in the biosynthesis of N-acyl ethanolamines that regulate energy metabolism and inflammation in the intestinal tract. Hydrolyzes N-acyl phosphatidylethanolamines to N-acyl lysophosphatidylethanolamines, which are further cleaved by a lysophospholipase D to release N-acyl ethanolamines (By similarity). May act in an autocrine and paracrine manner (By similarity). Has anti-helminth activity in a process regulated by gut microbiota. Upon helminth infection of intestinal epithelia, directly affects phosphatidylethanolamine contents in the membrane of helminth larvae, likely controlling an array of phospholipid-mediated cellular processes such as membrane fusion and cell division while providing for better immune recognition, ultimately reducing larvae integrity and infectivity (By similarity)., [UniProtKB, UniProtKB, UniProtKB, PubMed, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005102 signaling receptor binding;GO:0005543 phospholipid binding;GO:0005509 calcium ion binding;GO:0004623 phospholipase A2 activity;GO:0032052 bile acid binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0009986 cell surface", "go_biological_process": "GO:0008284 positive regulation of cell population proliferation;GO:0032869 cellular response to insulin stimulus;GO:0035556 intracellular signal transduction;GO:0043410 positive regulation of MAPK cascade;GO:0045944 positive regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 2.1, "record_id": "P00592-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P00772-1", "uniprot_id": "CELA1_PIG", "mass": 28821.0, "length": 266, "protein_name": "Chymotrypsin-like elastase family member 1", "gene_name": "CELA1", "organism": "Pig", "refseq_name": "chymotrypsin-like elastase family member 1 preproprotein", "refseq_ac": "NP_998988", "gene_names_uniprotkb": "CELA1; ELA1", "gene_names_refseq": "CELA1; ELA1; ELS1; Elastase-1", "protein_names_uniprotkb": "Chymotrypsin-like elastase family member 1; 3.4.21.36; Elastase-1", "protein_names_refseq": "chymotrypsin like elastase family member 1; chymotrypsin-like elastase family member 1 preproprotein; pancreatic elastase I", "tax_id": 9823, "disease": "", "pathway": " (ssc:396766)", "pathway_count": 1, "publication_count": 14, "publication_id_list": "10620133;17266656;19603802;20507992;26372354;33002681;3528137;3648024;4578945;5415108;5415110;628010;7656008;7922044", "class_list": "", "function": "Elastase-mediated membrane fusion of highly pathogenic porcine reproductive and respiratory syndrome virus at host cell surface., [RefSeq, PubMed]; Here, we studied the priming of SARS-CoV S by elastase and show an important role for residue Thr(795) in the S2 domain., [RefSeq, PubMed]; Insights into the PPE and HNE inhibition Publication Status: Online-Only, [RefSeq, PubMed]; Porcine pancreatic elastase (PPE) was crystallized in complex with a novel inhibitor at pH 5 and X-ray diffraction data were collected at a synchrotron source to 1.66 A., [RefSeq, PubMed]; Serine proteases that hydrolyze many proteins in addition to elastin., [UniProtKB, PubMed]; The oxygen of the oxopropyl group of the inhibitor is present as an oxygen anion rather than a hydroxyl group, supporting the role of the 'oxyanion hole' in stabilizing the tetrahedral intermediate in ELS1 catalysis, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q29625", "ec_number_list": "", "go_molecular_function": "GO:0004252 serine-type endopeptidase activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0006508 proteolysis;GO:0006954 inflammatory response", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "P00772-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P01165-1", "uniprot_id": "7B2_PIG", "mass": 23224.0, "length": 207, "protein_name": "Neuroendocrine protein 7B2", "gene_name": "SCG5", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "SCG5; SGNE1", "gene_names_refseq": "", "protein_names_uniprotkb": "Neuroendocrine protein 7B2; Secretogranin V; Secretogranin-5; Secretory granule endocrine protein I", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 6, "publication_id_list": "11439082;1797712;3234177;6514132;6625600;6816630", "class_list": "", "function": "Acts as a molecular chaperone for PCSK2/PC2, preventing its premature activation in the regulated secretory pathway. Binds to inactive PCSK2 in the endoplasmic reticulum and facilitates its transport from there to later compartments of the secretory pathway where it is proteolytically matured and activated. Also required for cleavage of PCSK2 but does not appear to be involved in its folding. Plays a role in regulating pituitary hormone secretion. The C-terminal peptide inhibits PCSK2 in vitro., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004857 enzyme inhibitor activity;GO:0051082 unfolded protein binding;GO:0030234 enzyme regulator activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0030141 secretory granule", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0007218 neuropeptide signaling pathway;GO:0016486 peptide hormone processing;GO:0046883 regulation of hormone secretion", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P01165-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P01274-1", "uniprot_id": "GLUC_PIG", "mass": 21029.0, "length": 180, "protein_name": "Pro-glucagon", "gene_name": "GCG", "organism": "Pig", "refseq_name": "pro-glucagon precursor", "refseq_ac": "NP_999489", "gene_names_uniprotkb": "GCG", "gene_names_refseq": "GCG; GLP-1", "protein_names_uniprotkb": "Pro-glucagon", "protein_names_refseq": "pro-glucagon precursor; pro-glucagon; proglucagon", "tax_id": 9823, "disease": "", "pathway": " (ssc:397595); (R-SSC-163359); (R-SSC-381771); (R-SSC-416476); (R-SSC-420092); (R-SSC-422085)", "pathway_count": 6, "publication_count": 13, "publication_id_list": "10322410;10605628;12554744;12626323;171582;25378285;27142747;2753890;28242256;3379036;3530719;6894800;7045833", "class_list": "", "function": "Data suggest that casein, safflower oil, sucrose, and sweetening agent rebaudioside A stimulate GLP1 release/secretion from enteroendocrine cells. (GLP1 = glucagon-like peptide 1, a peptide fragment derived from proglucagon), [RefSeq, PubMed]; May modulate gastric acid secretion and the gastro-pyloro-duodenal activity. May play an important role in intestinal mucosal growth in the early period of life., [UniProtKB, UniProtKB]; Plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis. A counterregulatory hormone of insulin, raises plasma glucose levels in response to insulin-induced hypoglycemia. Plays an important role in initiating and maintaining hyperglycemic conditions in diabetes. Binds to and activates the glucagon receptor GCGR, which couples to the G(s) G protein and elevates intracellular cAMP, triggering downstream metabolic responses., [UniProtKB, UniProtKB]; Potent stimulator of glucose-dependent insulin release. Also stimulates insulin release in response to IL6. Plays important roles on gastric motility and the suppression of plasma glucagon levels. May be involved in the suppression of satiety and stimulation of glucose disposal in peripheral tissues, independent of the actions of insulin. Has growth-promoting activities on intestinal epithelium. May also regulate the hypothalamic pituitary axis (HPA) via effects on LH, TSH, CRH, oxytocin, and vasopressin secretion. Increases islet mass through stimulation of islet neogenesis and pancreatic beta cell proliferation. Inhibits beta cell apoptosis., [UniProtKB, UniProtKB]; RYGB in lean pigs increases the response of GIP, total GLP-1, and insulin, but reduces levels of active GLP-1 in response to an oral glucose load. These data challenge the role of active GLP-1 as a contributor to remission from diabetes after RYGB, [RefSeq, PubMed]; Significantly reduces food intake. Inhibits gastric emptying in humans. Suppression of gastric emptying may lead to increased gastric distension, which may contribute to satiety by causing a sensation of fullness., [UniProtKB, UniProtKB]; Stimulates intestinal growth and up-regulates villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. The gastrointestinal tract, from the stomach to the colon is the principal target for GLP-2 action. Plays a key role in nutrient homeostasis, enhancing nutrient assimilation through enhanced gastrointestinal function, as well as increasing nutrient disposal. Stimulates intestinal glucose transport and decreases mucosal permeability., [UniProtKB, UniProtKB]; The patterns of colocalization of the K cell marker, glucagon-like insulinotropic peptide, and L cell markers, glucagon like peptide-1 and peptide YY, in enteroendocrine cells of the small intestine and colon of mouse and pig, were investigated., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q864V8", "ec_number_list": "", "go_molecular_function": "GO:0031769 glucagon receptor binding;GO:0042802 identical protein binding;GO:0005179 hormone activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005737 cytoplasm;GO:0005886 plasma membrane", "go_biological_process": "GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0043066 negative regulation of apoptotic process;GO:0070374 positive regulation of ERK1 and ERK2 cascade;GO:0071377 cellular response to glucagon stimulus;GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "P01274-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P05383-1", "uniprot_id": "KAPCB_PIG", "mass": 40594.0, "length": 351, "protein_name": "cAMP-dependent protein kinase catalytic subunit beta", "gene_name": "PRKACB", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "PRKACB", "gene_names_refseq": "", "protein_names_uniprotkb": "cAMP-dependent protein kinase catalytic subunit beta; 2.7.11.11; PKA C-beta", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 3, "publication_id_list": "10684253;2441988;9521123", "class_list": "", "function": "Mediates cAMP-dependent signaling triggered by receptor binding to GPCRs. PKA activation regulates diverse cellular processes such as cell proliferation, the cell cycle, differentiation and regulation of microtubule dynamics, chromatin condensation and decondensation, nuclear envelope disassembly and reassembly, as well as regulation of intracellular transport mechanisms and ion flux. Regulates the abundance of compartmentalized pools of its regulatory subunits through phosphorylation of PJA2 which binds and ubiquitinates these subunits, leading to their subsequent proteolysis. Phosphorylates GPKOW which regulates its ability to bind RNA. Acts as a negative regulator of mTORC1 by mediating phosphorylation of RPTOR., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 7, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0005524 ATP binding;GO:0004691 cAMP-dependent protein kinase activity;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0005952 cAMP-dependent protein kinase complex", "go_biological_process": "GO:0006468 protein phosphorylation;GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:1904262 negative regulation of TORC1 signaling", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "P05383-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P06199-1", "uniprot_id": "ACM2_PIG", "mass": 51673.0, "length": 466, "protein_name": "Muscarinic acetylcholine receptor M2", "gene_name": "CHRM2", "organism": "Pig", "refseq_name": "muscarinic acetylcholine receptor M2", "refseq_ac": "NP_999426", "gene_names_uniprotkb": "CHRM2", "gene_names_refseq": "CHRM2", "protein_names_uniprotkb": "Muscarinic acetylcholine receptor M2", "protein_names_refseq": "cardiac muscarinic acetylcholine receptor; muscarinic acetylcholine receptor M2", "tax_id": 9823, "disease": "", "pathway": " (ssc:397498); (R-SSC-390648); (R-SSC-418594); (R-SSC-8856825); (R-SSC-8856828)", "pathway_count": 5, "publication_count": 7, "publication_id_list": "18157728;18563417;20133950;20976005;3107123;3792556;9228066", "class_list": "", "function": "Data suggest that both M(2) and M(3) muscarinic receptors mediate the contraction in both pig clasp and sling fibers similar to human clasp and sling fibers., [RefSeq, PubMed]; Expression and function of M2 and M3 receptors are similar in the detrusor of juvenile and mature pigs., [RefSeq, PubMed]; M2 and M3 receptors are upregulated in a time-dependent and pressure-dependent fashion after as little as a 24 h exposure to increased hydrostatic pressure in bladder, [RefSeq, PubMed]; Muscarinic receptor for acetylcholine, a neurotransmitter found in the brain, neuromuscular junctions and the autonomic ganglia (PubMed:9228066). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors, such as adenylate cyclase (PubMed:9228066). CHRM2 is coupled to G(i)/G(o) (GNAI1 or GNAO1) G proteins and mediates signaling by inhibiting adenylate cyclase activity (By similarity)., [UniProtKB, PubMed, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 10, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0016907 G protein-coupled acetylcholine receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0030425 dendrite;GO:0045202 synapse;GO:0045211 postsynaptic membrane", "go_biological_process": "GO:0006940 regulation of smooth muscle contraction;GO:0007197 adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway;GO:0007213 G protein-coupled acetylcholine receptor signaling pathway;GO:0007187 G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007268 chemical synaptic transmission", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P06199-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P06296-1", "uniprot_id": "CRH_PIG", "mass": 20997.0, "length": 191, "protein_name": "Corticotropin-releasing hormone", "gene_name": "CRH", "organism": "Pig", "refseq_name": "corticoliberin precursor", "refseq_ac": "NP_001106533", "gene_names_uniprotkb": "CRH", "gene_names_refseq": "CRH", "protein_names_uniprotkb": "Corticotropin-releasing hormone; CRF; Corticoliberin; Corticotropin-releasing factor", "protein_names_refseq": "CRF; corticoliberin precursor; corticoliberin; corticotropin-releasing factor", "tax_id": 9823, "disease": "", "pathway": " (ssc:100127468); (R-SSC-373080)", "pathway_count": 2, "publication_count": 5, "publication_id_list": "12030933;16483545;20431270;3878520;9734873", "class_list": "", "function": "CRH inhibits local progesterone production from luteal cells in swine corpus lutem., [RefSeq, PubMed]; Evidence is provided for porcine corticotropin releasing hormone (CRH) as a quantitative trait locus (QTL) affecting growth and body composition. (corticotropin releasing hormone; CRH; CRF), [RefSeq, PubMed]; Hormone that plays a central role in whole body adaptation to stress (PubMed:3878520). Released by the hypothalamus primarily in response to physical or psychological stress and acts by binding to CRH receptor CRHR1, and to a lower extent, CRHR2 (By similarity). CRH-dependent signaling is a primary mediator of the neuroendocrine, autonomic (fight-or-flight) and behavioral responses to stress, acting as a key regulator of adaptation by activating the hypothalamus-pituitary-adrenal axis, leading to corticotropin hormone (ACTH) production (By similarity). Acts as a 'placental clock' during pregnancy, regulating gestational length, fetal development and the timing of labor (By similarity). Also acts as a regulator of blastocyst implantation by promoting decidualization, regulating trophoblast invasion and facilitating maternal immune tolerance (By similarity)., [UniProtKB, UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "O62637;Q0ZLZ2;Q8HZV1", "ec_number_list": "", "go_molecular_function": "GO:0017045 corticotropin-releasing hormone activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0043025 neuronal cell body;GO:0045202 synapse", "go_biological_process": "GO:0006954 inflammatory response;GO:0001963 synaptic transmission, dopaminergic;GO:0007565 female pregnancy;GO:0032811 negative regulation of epinephrine secretion;GO:0051461 positive regulation of corticotropin secretion", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P06296-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P07200-1", "uniprot_id": "TGFB1_PIG", "mass": 44280.0, "length": 390, "protein_name": "Transforming growth factor beta-1 proprotein", "gene_name": "TGFB1", "organism": "Pig", "refseq_name": "transforming growth factor beta-1 proprotein precursor", "refseq_ac": "NP_999180", "gene_names_uniprotkb": "TGFB1", "gene_names_refseq": "TGF-BETA-1; TGFB1", "protein_names_uniprotkb": "Transforming growth factor beta-1 proprotein", "protein_names_refseq": "transforming growth factor beta-1 proprotein precursor; transforming growth factor beta-1 proprotein; transforming growth factor, beta 1 (Camurati-Engelmann disease)", "tax_id": 9823, "disease": "", "pathway": " (ssc:397078); (R-SSC-114608); (R-SSC-2129379); (R-SSC-2173788); (R-SSC-2173789); (R-SSC-2173791); (R-SSC-3000170); (R-SSC-8941855); (R-SSC-8941858); (R-SSC-8951936); (R-SSC-9839389)", "pathway_count": 11, "publication_count": 12, "publication_id_list": "12030934;21677751;2461367;27882941;28142299;28360109;2879635;29109152;30541630;3166520;32661265;3470708", "class_list": "", "function": "Activated TGF-beta signaling rescued miR-143-reduced FSHR and intracellular signaling molecules, and miR-143-induced porcine granulosa cell apoptosis. Publication Status: Online-Only, [RefSeq, PubMed]; Hypochlorite-induced porcine model of peritoneal fibrosis through the activation of IL1beta-CX3CL1-TGFbeta1 signal axis. Publication Status: Online-Only, [RefSeq, PubMed]; Multifunctional protein that regulates the growth and differentiation of various cell types and is involved in various processes, such as normal development, immune function, microglia function and responses to neurodegeneration (By similarity). Activation into mature form follows different steps: following cleavage of the proprotein in the Golgi apparatus, Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains remain non-covalently linked rendering TGF-beta-1 inactive during storage in extracellular matrix. At the same time, LAP chain interacts with 'milieu molecules', such as LTBP1, LRRC32/GARP and LRRC33/NRROS that control activation of TGF-beta-1 and maintain it in a latent state during storage in extracellular milieus. TGF-beta-1 is released from LAP by integrins (ITGAV:ITGB6 or ITGAV:ITGB8): integrin-binding to LAP stabilizes an alternative conformation of the LAP bowtie tail and results in distortion of the LAP chain and subsequent release of the active TGF-beta-1. Once activated following release of LAP, TGF-beta-1 acts by binding to TGF-beta receptors (TGFBR1 and TGFBR2), which transduce signal (By similarity). While expressed by many cells types, TGF-beta-1 only has a very localized range of action within cell environment thanks to fine regulation of its activation by Latency-associated peptide chain (LAP) and 'milieu molecules'. Plays an important role in bone remodeling: acts as a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts. Can promote either T-helper 17 cells (Th17) or regulatory T-cells (Treg) lineage differentiation in a concentration-dependent manner. At high concentrations, leads to FOXP3-mediated suppression of RORC and down-regulation of IL-17 expression, favoring Treg cell development. At low concentrations in concert with IL-6 and IL-21, leads to expression of the IL-17 and IL-23 receptors, favoring differentiation to Th17 cells (By similarity). Stimulates sustained production of collagen through the activation of CREB3L1 by regulated intramembrane proteolysis (RIP). Mediates SMAD2/3 activation by inducing its phosphorylation and subsequent translocation to the nucleus. Positively regulates odontoblastic differentiation in dental papilla cells, via promotion of IPO7-mediated translocation of phosphorylated SMAD2 to the nucleus and subsequent transcription of target genes (By similarity). Can induce epithelial-to-mesenchymal transition (EMT) and cell migration in various cell types (By similarity)., [UniProtKB, UniProtKB, UniProtKB]; Required to maintain the Transforming growth factor beta-1 (TGF-beta-1) chain in a latent state during storage in extracellular matrix. Associates non-covalently with TGF-beta-1 and regulates its activation via interaction with 'milieu molecules', such as LTBP1, LRRC32/GARP and LRRC33/NRROS, that control activation of TGF-beta-1. Interaction with LRRC33/NRROS regulates activation of TGF-beta-1 in macrophages and microglia. Interaction with LRRC32/GARP controls activation of TGF-beta-1 on the surface of activated regulatory T-cells (Tregs). Interaction with integrins (ITGAV:ITGB6 or ITGAV:ITGB8) results in distortion of the Latency-associated peptide chain and subsequent release of the active TGF-beta-1., [UniProtKB, UniProtKB]; TGF-beta1-induced epithelial-myofibroblast plasticity is FAK- dependent, whereas TGF-beta1-induced apoptosis is favored when FAK signaling is inhibited., [RefSeq, PubMed]; TGFB1 can inhibit Salmonella replication whereas TRP53 can promote Salmonella replication in porcine peripheral blood mononuclear cells and murine macrophages. Publication Status: Online-Only, [RefSeq, PubMed]; This study shows that TGF-beta1 protects intestinal integrity and influences Smad and MAPK signal pathways in intestinal epithelium cells after TNF-alpha challenge, [RefSeq, PubMed]; Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 2, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 2, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 2, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 7, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "K7GQZ2;P08832", "ec_number_list": "", "go_molecular_function": "GO:0034714 type III transforming growth factor beta receptor binding;GO:0019899 enzyme binding;GO:0042802 identical protein binding;GO:0005125 cytokine activity;GO:0008083 growth factor activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0009986 cell surface;GO:0031012 extracellular matrix", "go_biological_process": "GO:0042307 positive regulation of protein import into nucleus;GO:0016202 regulation of striated muscle tissue development;GO:0032700 negative regulation of interleukin-17 production;GO:0085029 extracellular matrix assembly;GO:0032740 positive regulation of interleukin-17 production", "synthesized_glycan_count": 0, "hit_score": 1.5, "record_id": "P07200-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P09933-1", "uniprot_id": "PERT_PIG", "mass": 100443.0, "length": 926, "protein_name": "Thyroid peroxidase", "gene_name": "TPO", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "TPO", "gene_names_refseq": "", "protein_names_uniprotkb": "Thyroid peroxidase; 1.11.1.8; TPO", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 6, "publication_id_list": "12325367;1497352;2996435;3654642;3780975;7142155", "class_list": "", "function": "Iodination and coupling of the hormonogenic tyrosines in thyroglobulin to yield the thyroid hormones T(3) and T(4)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 4, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 4, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 4, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 6, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005509 calcium ion binding;GO:0020037 heme binding;GO:0004601 peroxidase activity;GO:0004447 iodide peroxidase activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0016020 membrane", "go_biological_process": "GO:0006979 response to oxidative stress;GO:0042446 hormone biosynthetic process;GO:0042744 hydrogen peroxide catabolic process;GO:0006590 thyroid hormone generation", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "P09933-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P0C5I2-1", "uniprot_id": "GMPPB_PIG", "mass": 39827.0, "length": 360, "protein_name": "Mannose-1-phosphate guanylyltransferase catalytic subunit beta", "gene_name": "GMPPB", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "GMPPB", "gene_names_refseq": "", "protein_names_uniprotkb": "Mannose-1-phosphate guanylyltransferase catalytic subunit beta; 2.7.7.13; GDP-mannose pyrophosphorylase 37-kDa subunit; GDP-mannose pyrophosphorylase B; GTP-mannose-1-phosphate guanylyltransferase beta", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 2, "publication_id_list": "11082198;7688733", "class_list": "", "function": "Catalytic subunit of the GMPPA-GMPPB mannose-1-phosphate guanylyltransferase complex (By similarity). Catalyzes the formation of GDP-mannose, an essential precursor of glycan moieties of glycoproteins and glycolipids (PubMed:11082198). Can catalyze the reverse reaction in vitro (By similarity). Together with GMPPA regulates GDP-alpha-D-mannose levels (By similarity)., [UniProtKB, PubMed, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004475 mannose-1-phosphate guanylyltransferase (GTP) activity;GO:0005525 GTP binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0120508 GDP-mannose pyrophosphorylase complex", "go_biological_process": "GO:0009298 GDP-mannose biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "P0C5I2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P0DTA4-1", "uniprot_id": "PCCA_PIG", "mass": 80180.0, "length": 730, "protein_name": "Propionyl-CoA carboxylase alpha chain, mitochondrial", "gene_name": "PCCA", "organism": "Pig", "refseq_name": "propionyl-CoA carboxylase alpha chain, mitochondrial", "refseq_ac": "XP_020921525", "gene_names_uniprotkb": "PCCA", "gene_names_refseq": "PCCA", "protein_names_uniprotkb": "Propionyl-CoA carboxylase alpha chain, mitochondrial; 6.4.1.3; PCCase subunit alpha; Propanoyl-CoA:carbon dioxide ligase subunit alpha", "protein_names_refseq": "PCCase subunit alpha; Propanoyl-CoA:carbon dioxide ligase subunit alpha; propionyl CoA carboxylase, alpha polypeptide; propionyl-CoA carboxylase alpha chain, mitochondrial; propionyl-CoA carboxylase alpha subunit", "tax_id": 9823, "disease": "", "pathway": " (ssc:100524103)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "13752080", "class_list": "", "function": "This is one of the 2 subunits of the biotin-dependent propionyl-CoA carboxylase (PCC), a mitochondrial enzyme involved in the catabolism of odd chain fatty acids, branched-chain amino acids isoleucine, threonine, methionine, and valine and other metabolites (PubMed:13752080). Propionyl-CoA carboxylase catalyzes the carboxylation of propionyl-CoA/propanoyl-CoA to D-methylmalonyl-CoA/(S)-methylmalonyl-CoA (PubMed:13752080). Within the holoenzyme, the alpha subunit catalyzes the ATP-dependent carboxylation of the biotin carried by the biotin carboxyl carrier (BCC) domain, while the beta subunit then transfers the carboxyl group from carboxylated biotin to propionyl-CoA (By similarity). Propionyl-CoA carboxylase also significantly acts on butyryl-CoA/butanoyl-CoA, which is converted to ethylmalonyl-CoA/(2S)-ethylmalonyl-CoA at a much lower rate (PubMed:13752080). Other alternative minor substrates include (2E)-butenoyl-CoA/crotonoyl-CoA (PubMed:13752080)., [UniProtKB, UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0004658 propionyl-CoA carboxylase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0019626 short-chain fatty acid catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "P0DTA4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P12682-1", "uniprot_id": "HMGB1_PIG", "mass": 24917.0, "length": 215, "protein_name": "High mobility group protein B1", "gene_name": "HMGB1", "organism": "Pig", "refseq_name": "high mobility group protein B1", "refseq_ac": "NP_001004034", "gene_names_uniprotkb": "HMGB1; HMG1", "gene_names_refseq": "HMGB1", "protein_names_uniprotkb": "High mobility group protein B1; HMG-1; High mobility group protein 1", "protein_names_refseq": "HMG-1; high mobility group protein 1; high mobility group protein B1; non-histone protein HMG1", "tax_id": 9823, "disease": "", "pathway": " (ssc:445521)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "14660645;18278457;22902066;26038024;3191113;32321806;34287039;34439812;35632744", "class_list": "", "function": "HMGB-1 may participate in the inflammatory response and liver injury in the late stage of acute liver failure, [RefSeq, PubMed]; High Mobility Group Box 1 in Pig Amniotic Membrane Experimentally Infected with E. coli O55. Publication Status: Online-Only, [RefSeq, PubMed]; High levels of HMGB1 in the small intestine and its relation to high levels of HMGB1 in plasma of piglets infected with E. coli O55 that suffered from infection correlated with high levels of inflammatory cytokines and bacterial translocation; levels were higher than HMGB1 levels in piglets with mild clinical symptoms, [RefSeq, PubMed]; In the cytoplasm proposed to dissociate the BECN1:BCL2 complex via competitive interaction with BECN1 leading to autophagy activation. Can protect BECN1 and ATG5 from calpain-mediated cleavage and thus proposed to control their proautophagic and proapoptotic functions and to regulate the extent and severity of inflammation-associated cellular injury. In myeloid cells has a protective role against endotoxemia and bacterial infection by promoting autophagy. Involved in endosomal translocation and activation of TLR9 in response to CpG-DNA in macrophages (By similarity)., [UniProtKB, UniProtKB, UniProtKB]; In the extracellular compartment (following either active secretion or passive release) involved in regulation of the inflammatory response. Fully reduced HGMB1 (which subsequently gets oxidized after release) in association with CXCL12 mediates the recruitment of inflammatory cells during the initial phase of tissue injury; the CXCL12:HMGB1 complex triggers CXCR4 homodimerization. Induces the migration of monocyte-derived immature dendritic cells and seems to regulate adhesive and migratory functions of neutrophils implicating AGER/RAGE and ITGAM. Can bind to various types of DNA and RNA including microbial unmethylated CpG-DNA to enhance the innate immune response to nucleic acids. Proposed to act in promiscuous DNA/RNA sensing which cooperates with subsequent discriminative sensing by specific pattern recognition receptors (By similarity). Promotes extracellular DNA-induced AIM2 inflammasome activation implicating AGER/RAGE. Disulfide HMGB1 binds to transmembrane receptors, such as AGER/RAGE, TLR2, TLR4 and probably TREM1, thus activating their signal transduction pathways (PubMed:14660645). Mediates the release of cytokines/chemokines such as TNF, IL-1, IL-6, IL-8, CCL2, CCL3, CCL4 and CXCL10. Promotes secretion of interferon-gamma by macrophage-stimulated natural killer (NK) cells in concert with other cytokines like IL-2 or IL-12. TLR4 is proposed to be the primary receptor promoting macrophage activation and signaling through TLR4 seems to implicate LY96/MD-2. In bacterial LPS- or LTA-mediated inflammatory responses binds to the endotoxins and transfers them to CD14 for signaling to the respective TLR4:LY96 and TLR2 complexes. Contributes to tumor proliferation by association with ACER/RAGE. Can bind to IL1-beta and signals through the IL1R1:IL1RAP receptor complex. Binding to class A CpG activates cytokine production in plasmacytoid dendritic cells implicating TLR9, MYD88 and AGER/RAGE and can activate autoreactive B cells. Via HMGB1-containing chromatin immune complexes may also promote B cell responses to endogenous TLR9 ligands through a B-cell receptor (BCR)-dependent and ACER/RAGE-independent mechanism. Inhibits phagocytosis of apoptotic cells by macrophages; the function is dependent on poly-ADP-ribosylation and involves binding to phosphatidylserine on the cell surface of apoptotic cells. In adaptive immunity may be involved in enhancing immunity through activation of effector T cells and suppression of regulatory T (TReg) cells. In contrast, without implicating effector or regulatory T-cells, required for tumor infiltration and activation of T-cells expressing the lymphotoxin LTA:LTB heterotrimer thus promoting tumor malignant progression. Also reported to limit proliferation of T-cells. Released HMGB1:nucleosome complexes formed during apoptosis can signal through TLR2 to induce cytokine production. Involved in induction of immunological tolerance by apoptotic cells; its pro-inflammatory activities when released by apoptotic cells are neutralized by reactive oxygen species (ROS)-dependent oxidation specifically on Cys-106. During macrophage activation by activated lymphocyte-derived self apoptotic DNA (ALD-DNA) promotes recruitment of ALD-DNA to endosomes (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, PubMed]; Multifunctional redox sensitive protein with various roles in different cellular compartments. In the nucleus is one of the major chromatin-associated non-histone proteins and acts as a DNA chaperone involved in replication, transcription, chromatin remodeling, V(D)J recombination, DNA repair and genome stability. Proposed to be an universal biosensor for nucleic acids. Promotes host inflammatory response to sterile and infectious signals and is involved in the coordination and integration of innate and adaptive immune responses. In the cytoplasm functions as a sensor and/or chaperone for immunogenic nucleic acids implicating the activation of TLR9-mediated immune responses, and mediates autophagy. Acts as a danger-associated molecular pattern (DAMP) molecule that amplifies immune responses during tissue injury. Released to the extracellular environment can bind DNA, nucleosomes, IL-1 beta, CXCL12, AGER isoform 2/sRAGE, lipopolysaccharide (LPS) and lipoteichoic acid (LTA), and activates cells through engagement of multiple surface receptors. In the extracellular compartment fully reduced HMGB1 (released by necrosis) acts as a chemokine, disulfide HMGB1 (actively secreted) as a cytokine, and sulfonyl HMGB1 (released from apoptotic cells) promotes immunological tolerance. Has proangiogenic activity. May be involved in platelet activation. Binds to phosphatidylserine and phosphatidylethanolamide. Bound to RAGE mediates signaling for neuronal outgrowth. May play a role in accumulation of expanded polyglutamine (polyQ) proteins (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Nuclear functions are attributed to fully reduced HGMB1. Associates with chromatin and binds DNA with a preference to non-canonical DNA structures such as single-stranded DNA, DNA-containing cruciforms or bent structures, supercoiled DNA and ZDNA. Can bent DNA and enhance DNA flexibility by looping thus providing a mechanism to promote activities on various gene promoters by enhancing transcription factor binding and/or bringing distant regulatory sequences into close proximity. May be involved in nucleotide excision repair (NER), mismatch repair (MMR) and base excision repair (BER) pathways, and double strand break repair such as non-homologous end joining (NHEJ). Involved in V(D)J recombination by acting as a cofactor of the RAG complex: acts by stimulating cleavage and RAG protein binding at the 23 bp spacer of conserved recombination signal sequences (RSS). In vitro can displace histone H1 from highly bent DNA. Can restructure the canonical nucleosome leading to relaxation of structural constraints for transcription factor-binding. Enhances binding of sterol regulatory element-binding proteins (SREBPs) such as SREBF1 to their cognate DNA sequences and increases their transcriptional activities. Facilitates binding of TP53 to DNA. May be involved in mitochondrial quality control and autophagy in a transcription-dependent fashion implicating HSPB1. Can modulate the activity of the telomerase complex and may be involved in telomere maintenance (By similarity). Represses porcine circovirus type 2 replication within the nucleus by binding to the Ori region of the viral genome (PubMed:32321806)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, PubMed]; Porcine Circovirus 2 Manipulates the PERK-ERO1alpha Axis of the Endoplasmic Reticulum To Favor Its Replication by Derepressing Viral DNA from HMGB1 Sequestration within Nuclei., [RefSeq, PubMed]; Systemic HMGB-1 levels were significantly elevated in both trauma groups when compared to the sham group. Haemorrhagic shock severity and duration were positively correlated with HMGB-1 levels and compared to baseline values, concentrations remained significantly increased in severe hemorrhage when compared to moderate hemorrhage., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0000400 four-way junction DNA binding;GO:0000405 bubble DNA binding;GO:0044378 non-sequence-specific DNA binding, bending;GO:0097100 supercoiled DNA binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0005634 nucleus;GO:0005768 endosome;GO:0005886 plasma membrane;GO:0000793 condensed chromosome", "go_biological_process": "GO:0002840 regulation of T cell mediated immune response to tumor cell;GO:0017055 negative regulation of RNA polymerase II transcription preinitiation complex assembly;GO:0006310 DNA recombination;GO:0006338 chromatin remodeling;GO:0006935 chemotaxis", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P12682-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P15145-1", "uniprot_id": "AMPN_PIG", "mass": 108832.0, "length": 963, "protein_name": "Aminopeptidase N", "gene_name": "ANPEP", "organism": "Pig", "refseq_name": "aminopeptidase N", "refseq_ac": "NP_999442", "gene_names_uniprotkb": "ANPEP", "gene_names_refseq": "ANPEP; APN; PEPN", "protein_names_uniprotkb": "Aminopeptidase N; 3.4.11.2; AP-M; AP-N; Alanyl aminopeptidase; Aminopeptidase M; Microsomal aminopeptidase; gp130; pAPN", "protein_names_refseq": "AP-M; AP-N; aminopeptidase M; aminopeptidase N; gp130; microsomal aminopeptidase; pAPN; porcine aminopeptidase N", "tax_id": 9823, "disease": "", "pathway": " (ssc:397520)", "pathway_count": 1, "publication_count": 17, "publication_id_list": "1350661;1977382;22876187;2568950;27449937;28363778;30315482;3121301;33114247;34406863;6119979;7911642;7913510;8672129;8963385;8985407;9634079", "class_list": "", "function": "(Microbial infection) In case of porcine transmissible gastroenteritis coronavirus (TGEV) and porcine respiratory coronavirus (PRCoV) infections, serves as a receptor for TGEV and PRCoV spike glycoprotein in a species-specific manner., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]; Aminopeptidase N Is an Entry Co-factor Triggering Porcine Deltacoronavirus Entry via an Endocytotic Pathway., [RefSeq, PubMed]; Broad specificity aminopeptidase which plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Also involved in the processing of various peptides including peptide hormones, such as angiotensin III and IV, neuropeptides, and chemokines. May also be involved the cleavage of peptides bound to major histocompatibility complex class II molecules of antigen presenting cells. May have a role in angiogenesis and promote cholesterol crystallization (By similarity). It is able to degrade Leu-enkephalin and Met-enkephalin but not cholecystokinin CCK8, neuromedin C (GRP-10), somatostatin-14, substance P and vasoactive intestinal peptide (PubMed:8963385). May have a role in amino acid transport by acting as binding partner of amino acid transporter SLC6A19 and regulating its activity (By similarity)., [UniProtKB, UniProtKB, UniProtKB, PubMed]; Genetic ablation of APN expression had no effect on infectability by porcine epidemic diarrhea virus, demonstrating that APN is not essential for porcine epidemic diarrhea virus cell entry., [RefSeq, PubMed]; Immunohistochemistry confirmed the presence of PEDV reactivity and absence of TGEV reactivity in the enterocytes lining the ileum in ANPEP null pigs. The different receptor requirements for TGEV and PEDV have important implications in the development of new genetic tools for the control of enteric disease in pigs., [RefSeq, PubMed]; PAPN is not a functional receptor for porcine epidemic diarrhea virus, but promotes the infection of PEDV through its protease activity., [RefSeq, PubMed]; The Cell Tropism of Porcine Respiratory Coronavirus for Airway Epithelial Cells Is Determined by the Expression of Porcine Aminopeptidase N. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 13, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 13, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 13, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 14, "binding_glycan_count": 0, "secondary_ac_list": "Q29242", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0001618 virus receptor activity;GO:0070006 metalloaminopeptidase activity;GO:0016285 alanyl aminopeptidase activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005886 plasma membrane", "go_biological_process": "GO:0001525 angiogenesis;GO:0030154 cell differentiation;GO:0002003 angiotensin maturation;GO:0043171 peptide catabolic process", "synthesized_glycan_count": 0, "hit_score": 3.1, "record_id": "P15145-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P16276-1", "uniprot_id": "ACON_PIG", "mass": 85761.0, "length": 781, "protein_name": "Aconitate hydratase, mitochondrial", "gene_name": "ACO2", "organism": "Pig", "refseq_name": "aconitate hydratase, mitochondrial precursor", "refseq_ac": "NP_999119", "gene_names_uniprotkb": "ACO2", "gene_names_refseq": "ACO2", "protein_names_uniprotkb": "Aconitate hydratase, mitochondrial; 4.2.1.3; Aconitase; Citrate hydro-lyase", "protein_names_refseq": "aconitate hydratase, mitochondrial precursor; aconitate hydratase, mitochondrial; citrate hydro-lyase; heart aconitase", "tax_id": 9823, "disease": "", "pathway": " (ssc:396999)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "10631981;16142896;2303429;2726740;27818104;2798408", "class_list": "", "function": "Catalyzes the isomerization of citrate to isocitrate via cis-aconitate., [UniProtKB, PubMed]; Study examined the sites and mechanisms of aconitase inactivation by peroxynitrite (ONOO-), a strong oxidant and nitrating agent readily formed from superoxide anion and nitric oxide generated by mitochondria, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003994 aconitate hydratase activity;GO:0046872 metal ion binding;GO:0051539 4 iron, 4 sulfur cluster binding", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005829 cytosol", "go_biological_process": "GO:0006099 tricarboxylic acid cycle", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P16276-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P16469-1", "uniprot_id": "LOX15_PIG", "mass": 75004.0, "length": 663, "protein_name": "Polyunsaturated fatty acid lipoxygenase ALOX15", "gene_name": "ALOX15", "organism": "Pig", "refseq_name": "polyunsaturated fatty acid lipoxygenase ALOX15", "refseq_ac": "NP_999096", "gene_names_uniprotkb": "ALOX15", "gene_names_refseq": "12-LOX; 15-LOX; ALOX12; ALOX15", "protein_names_uniprotkb": "Polyunsaturated fatty acid lipoxygenase ALOX15; 1.13.11.-; 1.13.11.12; 1.13.11.31; 1.13.11.33; 12-LOX; 12/15-lipoxygenase; 15-LOX; Arachidonate 12-lipoxygenase, leukocyte-type; Arachidonate 15-lipoxygenase; Arachidonate omega-6 lipoxygenase; Erythroid cell-specific 15-lipoxygenase; Hepoxilin A3 synthase Alox15; Linoleate 13S-lipoxygenase", "protein_names_refseq": "12/15-lipoxygenase; 12S-LOX; 12S-lipoxygenase; arachidonate 12-lipoxygenase, 12S-type; arachidonate 12-lipoxygenase, leukocyte-type; arachidonate omega-6 lipoxygenase; erythroid cell-specific 15-lipoxygenase; hepoxilin A3 synthase Alox15; linoleate 13S-lipoxygenase; polyunsaturated fatty acid lipoxygenase ALOX15", "tax_id": 9823, "disease": "", "pathway": " (ssc:396971); (R-SSC-2142691); (R-SSC-2142712); (R-SSC-2142770); (R-SSC-9018677); (R-SSC-9018681); (R-SSC-9018896); (R-SSC-9023661); (R-SSC-9025106); (R-SSC-9026286)", "pathway_count": 10, "publication_count": 9, "publication_id_list": "1601885;17493578;18311922;18635820;19324874;19683507;22795085;2315307;8305485", "class_list": "", "function": "12/15-Lipoxygenase activity increases the degradation of macrophage ATP-binding cassette transporter G1., [RefSeq, PubMed]; EPR spectroscopy and electrospray mass spectroscopy reveal distinctive features of the iron site in leukocyte arachidonate 12-lipoxygenase., [RefSeq, PubMed]; Non-heme iron-containing dioxygenase that catalyzes the stereo-specific peroxidation of free and esterified polyunsaturated fatty acids generating a spectrum of bioactive lipid mediators (PubMed:17493578, PubMed:18311922, PubMed:19324874, PubMed:8305485). It inserts peroxyl groups at C12 or C15 of arachidonate ((5Z,8Z,11Z,14Z)-eicosatetraenoate) producing both 12-hydroperoxyeicosatetraenoate/12-HPETE and 15-hydroperoxyeicosatetraenoate/15-HPETE (PubMed:17493578, PubMed:8305485). It may then act on 12-HPETE to produce hepoxilins, which may show pro-inflammatory properties (By similarity). Can also peroxidize linoleate ((9Z,12Z)-octadecadienoate) to 13-hydroperoxyoctadecadienoate. May participate in the sequential oxidations of DHA ((4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate) to generate specialized pro-resolving mediators (SPMs)like resolvin D5 ((7S,17S)-diHPDHA) and (7S,14S)-diHPDHA, that actively down-regulate the immune response and have anti-aggregation properties with platelets. Can convert epoxy fatty acids to hydroperoxy-epoxides derivatives followed by an intramolecular nucleophilic substitution leading to the formation of monocyclic endoperoxides (By similarity). Plays an important role during the maintenance of self-tolerance by peroxidizing membrane-bound phosphatidylethanolamine which can then signal the sorting process for clearance of apoptotic cells during inflammation and prevent an autoimmune response. In addition to its role in the immune and inflammatory responses, this enzyme may play a role in epithelial wound healing in the cornea through production of lipoxin A4 (LXA(4)) and docosahexaenoic acid-derived neuroprotectin D1 (NPD1; 10R,17S-HDHA), both lipid autacoids exhibit anti-inflammatory and neuroprotective properties. Furthermore, it may regulate actin polymerization which is crucial for several biological processes such as the phagocytosis of apoptotic cells. It is also implicated in the generation of endogenous ligands for peroxisome proliferator activated receptor (PPAR-gamma), hence modulating macrophage development and function. It may also exert a negative effect on skeletal development by regulating bone mass through this pathway. As well as participates in ER stress and downstream inflammation in adipocytes, pancreatic islets, and liver (By similarity). Finally, it is also involved in the cellular response to IL13/interleukin-13 (By similarity)., [UniProtKB, UniProtKB, PubMed, PubMed, PubMed, UniProtKB, UniProtKB, PubMed]; The crystal structure of a mammalian 12-lipoxygenase reveals a plausible substrate access channel for oxygen., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 14, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "F1RFT4", "ec_number_list": "", "go_molecular_function": "GO:0005506 iron ion binding;GO:0005546 phosphatidylinositol-4,5-bisphosphate binding;GO:0004052 arachidonate 12(S)-lipoxygenase activity;GO:0016165 linoleate 13S-lipoxygenase activity;GO:0050473 arachidonate 15-lipoxygenase activity", "go_cellular_component": "GO:0005811 lipid droplet;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0016020 membrane;GO:0009898 cytoplasmic side of plasma membrane", "go_biological_process": "GO:0034440 lipid oxidation;GO:0006629 lipid metabolic process;GO:0070374 positive regulation of ERK1 and ERK2 cascade;GO:0043651 linoleic acid metabolic process;GO:0071277 cellular response to calcium ion", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P16469-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P16549-1", "uniprot_id": "FMO1_PIG", "mass": 59952.0, "length": 532, "protein_name": "Flavin-containing monooxygenase 1", "gene_name": "FMO1", "organism": "Pig", "refseq_name": "flavin-containing monooxygenase 1", "refseq_ac": "NP_999229", "gene_names_uniprotkb": "FMO1; FMO-1", "gene_names_refseq": "FMO1", "protein_names_uniprotkb": "Flavin-containing monooxygenase 1; 1.14.13.148; 1.14.13.8; Dimethylaniline monooxygenase [N-oxide-forming] 1; Dimethylaniline oxidase 1; FMO 1; Hepatic flavin-containing monooxygenase 1; Trimethylamine monooxygenase", "protein_names_refseq": "FMO 1; dimethylaniline monooxygenase [N-oxide-forming] 1; dimethylaniline oxidase 1; flavin containing monooxygenase 1; flavin-containing monooxygenase 1; hepatic flavin-containing monooxygenase (FMO); hepatic flavin-containing monooxygenase 1; trimethylamine monooxygenase", "tax_id": 9823, "disease": "", "pathway": " (ssc:397132); (R-SSC-1614558); (R-SSC-217271)", "pathway_count": 3, "publication_count": 4, "publication_id_list": "2322534;2383273;7758472;9778310", "class_list": "", "function": "Broad spectrum monooxygenase that catalyzes the oxygenation of a wide variety of nitrogen- and sulfur-containing compounds including xenobiotics (PubMed:7758472). Catalyzes the S-oxygenation of hypotaurine to produce taurine, an organic osmolyte involved in cell volume regulation as well as a variety of cytoprotective and developmental processes (By similarity). In vitro, catalyzes the N-oxygenation of trimethylamine (TMA) to produce trimethylamine N-oxide (TMAO) and could therefore participate to the detoxification of this compound that is generated by the action of gut microbiota from dietary precursors such as choline, choline containing compounds, betaine or L-carnitine (By similarity)., [UniProtKB, UniProtKB, UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 1, "mined_n_glycosites": 1, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 1, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 1, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 1, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0050660 flavin adenine dinucleotide binding;GO:0034899 trimethylamine monooxygenase activity;GO:0050661 NADP binding;GO:0004499 N,N-dimethylaniline monooxygenase activity;GO:0047822 hypotaurine monooxygenase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0009404 toxin metabolic process;GO:0042412 taurine biosynthetic process;GO:0006082 organic acid metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P16549-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P18434-1", "uniprot_id": "ATP4B_PIG", "mass": 33076.0, "length": 290, "protein_name": "Potassium-transporting ATPase subunit beta", "gene_name": "ATP4B", "organism": "Pig", "refseq_name": "potassium-transporting ATPase subunit beta", "refseq_ac": "NP_001001258", "gene_names_uniprotkb": "ATP4B", "gene_names_refseq": "ATP4B", "protein_names_uniprotkb": "Potassium-transporting ATPase subunit beta; Gastric H(+)/K(+) ATPase subunit beta; Proton pump beta chain; gp60-90", "protein_names_refseq": "ATPase H+/K+ transporting beta subunit; gastric H(+)/K(+) ATPase subunit beta; gastric H+/K+-ATPase beta subunit; gp60-90; potassium-transporting ATPase subunit beta; proton pump beta chain", "tax_id": 9823, "disease": "", "pathway": " (ssc:397131); (R-SSC-936837)", "pathway_count": 2, "publication_count": 7, "publication_id_list": "12645953;19387495;1974721;21224846;2159787;25231997;29618813", "class_list": "", "function": "New cryo-electron microscopic structures of H+,K+-ATPase using a phosphate analog and a specific antagonist, SCH28080., [RefSeq, PubMed]; The beta subunit of the gastric H(+)/K(+) ATPase pump which transports H(+) ions in exchange for K(+) ions across the apical membrane of parietal cells. Plays a structural and regulatory role in the assembly and membrane targeting of a functionally active pump (By similarity). Within a transport cycle, the transfer of a H(+) ion across the membrane is coupled to ATP hydrolysis and is associated with a transient phosphorylation of the alpha subunit that shifts the pump conformation from inward-facing (E1) to outward-facing state (E2). Interacts with the phosphorylation domain of the alpha subunit and functions as a ratchet, stabilizing the lumenal-open E2 conformation and preventing the reverse reaction of the transport cycle (PubMed:19387495, PubMed:29618813)., [UniProtKB, PubMed, UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 6, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 6, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 6, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 6, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0001671 ATPase activator activity", "go_cellular_component": "GO:0016324 apical plasma membrane;GO:0005890 sodium:potassium-exchanging ATPase complex", "go_biological_process": "GO:0007155 cell adhesion;GO:0006883 intracellular sodium ion homeostasis;GO:0030007 intracellular potassium ion homeostasis;GO:0036376 sodium ion export across plasma membrane;GO:1990573 potassium ion import across plasma membrane", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "P18434-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P19156-1", "uniprot_id": "ATP4A_PIG", "mass": 114287.0, "length": 1034, "protein_name": "Potassium-transporting ATPase alpha chain 1", "gene_name": "ATP4A", "organism": "Pig", "refseq_name": "potassium-transporting ATPase alpha chain 1", "refseq_ac": "NP_999456", "gene_names_uniprotkb": "ATP4A", "gene_names_refseq": "ATP4A", "protein_names_uniprotkb": "Potassium-transporting ATPase alpha chain 1; 7.2.2.19; Gastric H(+)/K(+) ATPase subunit alpha; Proton pump", "protein_names_refseq": "(H+ + K+)-ATPase; ATPase H+/K+ transporting alpha subunit; ATPase, H+/K+ exchanging, alpha polypeptide; gastric H(+)/K(+) ATPase subunit alpha; potassium-transporting ATPase alpha chain 1; proton pump", "tax_id": 9823, "disease": "", "pathway": " (ssc:397552)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "10891352;12645953;1720615;19387495;21224846;25231997;2848518;29618813;30143663;3017315;31436534;7797539;8886014", "class_list": "", "function": "A lower number of K(+) ions bind at lower pH, modeled by a higher number of protons in the cation binding pocket of H(+), K(+)-ATPase, in agreement with the 'transport stoichiometry variation' hypothesis. Publication Status: Online-Only, [RefSeq, PubMed]; New cryo-electron microscopic structures of H+,K+-ATPase using a phosphate analog and a specific antagonist, SCH28080., [RefSeq, PubMed]; The catalytic subunit of the gastric H(+)/K(+) ATPase pump which transports H(+) ions in exchange for K(+) ions across the apical membrane of parietal cells. Uses ATP as an energy source to pump H(+) ions to the gastric lumen while transporting K(+) ion from the lumen into the cell (By similarity). Remarkably generates a million-fold proton gradient across the gastric parietal cell membrane, acidifying the gastric juice down to pH 1 (By similarity). Within a transport cycle, the transfer of a H(+) ion across the membrane is coupled to ATP hydrolysis and is associated with a transient phosphorylation that shifts the pump conformation from inward-facing (E1) to outward-facing state (E2). The release of the H(+) ion in the stomach lumen is followed by binding of K(+) ion converting the pump conformation back to the E1 state (PubMed:19387495, PubMed:29618813, PubMed:30143663, PubMed:31436534)., [UniProtKB, PubMed, PubMed, PubMed, UniProtKB, PubMed, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 7, "reported_mutagensis": 15, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0030955 potassium ion binding;GO:0005391 P-type sodium:potassium-exchanging transporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016324 apical plasma membrane;GO:0090533 cation-transporting ATPase complex;GO:0098797 plasma membrane protein complex", "go_biological_process": "GO:0006883 intracellular sodium ion homeostasis;GO:0030007 intracellular potassium ion homeostasis;GO:0036376 sodium ion export across plasma membrane;GO:1990573 potassium ion import across plasma membrane;GO:0071805 potassium ion transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "P19156-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P19619-1", "uniprot_id": "ANXA1_PIG", "mass": 38759.0, "length": 346, "protein_name": "Annexin A1", "gene_name": "ANXA1", "organism": "Pig", "refseq_name": "annexin A1", "refseq_ac": "NP_001157470", "gene_names_uniprotkb": "ANXA1; ANX1", "gene_names_refseq": "ANX1; ANXA1", "protein_names_uniprotkb": "Annexin A1; Annexin I; Annexin-1; Calpactin II; Calpactin-2; Chromobindin-9; Lipocortin I; Phospholipase A2 inhibitory protein; p35", "protein_names_refseq": "annexin A1; annexin I; annexin-1; calpactin II; calpactin-2; chromobindin-9; lipocortin I; p35; phospholipase A2 inhibitory protein", "tax_id": 9823, "disease": "", "pathway": " (ssc:396942)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "11058080;11178908;12595246;15544840;15581623;18641677;25204809;3020049;8885232", "class_list": "", "function": "Annexin I is regulated by an anti-apoptotic Bcl-2 protein in Tumor Necrosis Factor-alpha-induced renal apoptotic events, [RefSeq, PubMed]; Data suggest amino acid substitution in ANXA1 (S27E; S27A) at site of post-translational phosphorylation affects protein stability, core domain calcium binding affinity, core domain/N-terminal domain structures, and N-terminal domain orientation., [RefSeq, PubMed]; Functions at least in part by activating the formyl peptide receptors and downstream signaling cascades. Promotes chemotaxis of granulocytes and monocytes via activation of the formyl peptide receptors. Promotes rearrangement of the actin cytoskeleton, cell polarization and cell migration. Promotes resolution of inflammation and wound healing. Acts via neutrophil N-formyl peptide receptors to enhance the release of CXCL2., [UniProtKB, UniProtKB]; Plays important roles in the innate immune response as effector of glucocorticoid-mediated responses and regulator of the inflammatory process. Has anti-inflammatory activity. Plays a role in glucocorticoid-mediated down-regulation of the early phase of the inflammatory response. Contributes to the adaptive immune response by enhancing signaling cascades that are triggered by T-cell activation, regulates differentiation and proliferation of activated T cells. Promotes the differentiation of T cells into Th1 cells and negatively regulates differentiation into Th2 cells (By similarity). Has no effect on unstimulated T cells. Negatively regulates hormone exocytosis via activation of the formyl peptide receptors and reorganization of the actin cytoskeleton (By similarity). Has high affinity for Ca(2+) and can bind up to eight Ca(2+) ions (PubMed:12595246). Displays Ca(2+)-dependent binding to phospholipid membranes (PubMed:8885232). Plays a role in the formation of phagocytic cups and phagosomes. Plays a role in phagocytosis by mediating the Ca(2+)-dependent interaction between phagosomes and the actin cytoskeleton (By similarity). In the context of antitumor immunity, interacts with FPR1 on dendritic cells allowing for tumor-associated antigens uptake and cross-presentation to T cells to mount an antitumor specific T cell response., [UniProtKB, UniProtKB, UniProtKB, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q29547", "ec_number_list": "", "go_molecular_function": "GO:0005509 calcium ion binding;GO:0005544 calcium-dependent phospholipid binding;GO:0019834 phospholipase A2 inhibitor activity;GO:0001786 phosphatidylserine binding", "go_cellular_component": "GO:0001891 phagocytic cup;GO:0005615 extracellular space;GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005886 plasma membrane", "go_biological_process": "GO:0006954 inflammatory response;GO:0007165 signal transduction;GO:0045087 innate immune response;GO:0046883 regulation of hormone secretion;GO:0006909 phagocytosis", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P19619-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P19620-1", "uniprot_id": "ANXA2_PIG", "mass": 38534.0, "length": 339, "protein_name": "Annexin A2", "gene_name": "ANXA2", "organism": "Pig", "refseq_name": "annexin A2", "refseq_ac": "NP_001005726", "gene_names_uniprotkb": "ANXA2; ANX2", "gene_names_refseq": "ANXA2", "protein_names_uniprotkb": "Annexin A2; Annexin II; Annexin-2; Calpactin I heavy chain; Calpactin-1 heavy chain; Chromobindin-8; Lipocortin II; PAP-IV; Placental anticoagulant protein IV; Protein I; p36", "protein_names_refseq": "PAP-IV; annexin A2; annexin II; annexin-2; calpactin I heavy chain; calpactin-1 heavy chain; chromobindin-8; lipocortin II; p36; placental anticoagulant protein IV; protein I", "tax_id": 9823, "disease": "", "pathway": " (ssc:406192)", "pathway_count": 1, "publication_count": 12, "publication_id_list": "14661980;16263068;17607745;19367723;2456953;24874199;25593157;25701745;2937654;2973411;30053894;35215950", "class_list": "", "function": "(Microbial infection) May serve as a receptor for classical swine fever virus (CSFV) (PubMed:25701745). Promotes CSFV infection (PubMed:25701745)., [UniProtKB, PubMed]; ANXA2 can interact with vimentin and enhance porcine reproductive and respiratory syndrome virus (PRRSV) growth. This contributes to the regulation of PRRSV replication in infected cells and may have implications for the future antiviral strategies. Erratum:[Vet Res. 2018 Oct 5;49(1):103. doi: 10.1186/s13567-018-0595-x. PMID: 30290850] Publication Status: Online-Only, [RefSeq, PubMed]; Amino acids R338, N359, G378 of NS5A were revealed to be pivotal for the ANXA2-NS5A interaction., [RefSeq, PubMed]; An octameric model is proposed for the annexin A2/p11(S100A10) complex, which exerts annexin A2 function. The proposed structure of the annexin A2/p11 octamer sheds new light into annexin A2/p11 interaction., [RefSeq, PubMed]; Annexin A2 acts in exocytic apical membrane trafficking in small intestinal enterocytes and is proteolytically cleaved in situ by pancreatic proteinases once it has become externalized to the lumenal side of the brush border membrane. [annexin A2], [RefSeq, PubMed]; Calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. May be involved in heat-stress response. Inhibits PCSK9-enhanced LDLR degradation, probably reduces PCSK9 protein levels via a translational mechanism but also competes with LDLR for binding with PCSK9. Binds to endosomes damaged by phagocytosis of particulate wear debris and participates in endosomal membrane stabilization, thereby limiting NLRP3 inflammasome activation (By similarity). Required for endothelial cell surface plasmin generation and may support fibrinolytic surveillance and neoangiogenesis (By similarity)., [UniProtKB, UniProtKB, UniProtKB]; Encephalomyocarditis Virus 2A Protein Inhibited Apoptosis by Interaction with Annexin A2 through JNK/c-Jun Pathway. Publication Status: Online-Only, [RefSeq, PubMed]; In conclusion, Annexin 2 is the novel host protein identified to interact with classical swine fever virus E2 and promote virus multiplication., [RefSeq, PubMed]; Taken together, these results indicate that Nsp9 binding partner ANXA2 is beneficial for porcine reproductive and respiratory syndrome virus replication., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q5Y2C7", "ec_number_list": "", "go_molecular_function": "GO:0005509 calcium ion binding;GO:0008092 cytoskeletal protein binding;GO:0005544 calcium-dependent phospholipid binding;GO:0044548 S100 protein binding;GO:0001786 phosphatidylserine binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005768 endosome;GO:0005886 plasma membrane;GO:0042470 melanosome", "go_biological_process": "GO:0010756 positive regulation of plasminogen activation;GO:0007155 cell adhesion;GO:0044794 host-mediated activation of viral process;GO:1903902 positive regulation of viral life cycle", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "P19620-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P20192-1", "uniprot_id": "DGKA_PIG", "mass": 82606.0, "length": 734, "protein_name": "Diacylglycerol kinase alpha", "gene_name": "DGKA", "organism": "Pig", "refseq_name": "diacylglycerol kinase alpha", "refseq_ac": "NP_999197", "gene_names_uniprotkb": "DGKA; DAGK1; DAGK", "gene_names_refseq": "DAGK1; DAGK; DGKA", "protein_names_uniprotkb": "Diacylglycerol kinase alpha; 2.7.1.107; 2.7.1.93; 80 kDa diacylglycerol kinase; DAG kinase alpha; DGK-alpha; Diglyceride kinase alpha", "protein_names_refseq": "80 kDa diacylglycerol kinase; DAG kinase alpha; DGK-alpha; diacylglycerol kinase alpha; diglyceride kinase alpha", "tax_id": 9823, "disease": "", "pathway": " (ssc:397097); (R-SSC-114508)", "pathway_count": 2, "publication_count": 5, "publication_id_list": "2156169;22199356;23949095;8034597;8809050", "class_list": "", "function": "Diacylglycerol kinase that converts diacylglycerol/DAG into phosphatidic acid/phosphatidate/PA and regulates the respective levels of these two bioactive lipids (PubMed:8034597). Thereby, acts as a central switch between the signaling pathways activated by these second messengers with different cellular targets and opposite effects in numerous biological processes (PubMed:8034597). Also plays an important role in the biosynthesis of complex lipids. Can also phosphorylate 1-alkyl-2-acylglycerol in vitro as efficiently as diacylglycerol provided it contains an arachidonoyl group. Also involved in the production of alkyl-lysophosphatidic acid, another bioactive lipid, through the phosphorylation of 1-alkyl-2-acetyl glycerol (By similarity)., [UniProtKB, UniProtKB, PubMed]; The nucleo-cytoplasmic shuttling of DGKalpha is orchestrated by tyrosine phosphorylation by the Src-activated tyrosine kinase c-Abl, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 6, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004143 ATP-dependent diacylglycerol kinase activity;GO:0005524 ATP binding;GO:0008270 zinc ion binding;GO:0005509 calcium ion binding;GO:0047649 alkylglycerol kinase activity", "go_cellular_component": "GO:0005829 cytosol;GO:0005886 plasma membrane", "go_biological_process": "GO:0046339 diacylglycerol metabolic process;GO:0046834 lipid phosphorylation;GO:0006654 phosphatidic acid biosynthetic process;GO:0035556 intracellular signal transduction;GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P20192-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P22412-1", "uniprot_id": "DPEP1_PIG", "mass": 44700.0, "length": 409, "protein_name": "Dipeptidase 1", "gene_name": "DPEP1", "organism": "Pig", "refseq_name": "dipeptidase 1 precursor", "refseq_ac": "NP_999273", "gene_names_uniprotkb": "DPEP1; RDP", "gene_names_refseq": "DPEP1; RDP", "protein_names_uniprotkb": "Dipeptidase 1; 3.4.13.19; 3.5.2.6; Beta-lactamase; Microsomal dipeptidase; Renal dipeptidase", "protein_names_refseq": "beta-lactamase; dipeptidase 1 (renal); dipeptidase 1 precursor; microsomal dipeptidase; renal dipeptidase", "tax_id": 9823, "disease": "", "pathway": " (ssc:397196); (R-SSC-2142691); (R-SSC-5423646)", "pathway_count": 3, "publication_count": 8, "publication_id_list": "16689534;19022244;2137335;2173907;22742779;38568806;8045301;8823187", "class_list": "", "function": "Association of GPI-anchored membrane dipeptidase with detergent-resistant membranes facilitates its trafficking through the early secretory pathway, at a level between the endoplasmic reticulum and the cis-Golgi., [RefSeq, PubMed]; Hydrolyzes a wide range of dipeptides (PubMed:8045301, PubMed:8823187). Hydrolyzes the conversion of leukotriene D4 to leukotriene E4. Hydrolyzes cystinyl-bis-glycine (cys-bis-gly) formed during glutathione degradation. Also possesses beta lactamase activity and hydrolytically inactivates beta-lactam antibiotics (By similarity)., [UniProtKB, PubMed, PubMed, UniProtKB]; Independently of its dipeptidase activity, acts as an adhesion receptor for neutrophil recruitment from bloodstream into inflamed lungs and liver., [UniProtKB, UniProtKB]; Memebrane dipeptidase catalyzed the hydrolysis of cysteinylglycine conjugates, but the rate of this activity was strongly dependent on the nature of the substituent on the cysteine sulfur atom., [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 1, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 1, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 1, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 15, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0034235 GPI anchor binding;GO:0008270 zinc ion binding;GO:0042802 identical protein binding;GO:0070573 metallodipeptidase activity;GO:0072341 modified amino acid binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005886 plasma membrane;GO:0045177 apical part of cell;GO:0005789 endoplasmic reticulum membrane;GO:0016324 apical plasma membrane", "go_biological_process": "GO:0006751 glutathione catabolic process;GO:0006508 proteolysis;GO:0032869 cellular response to insulin stimulus;GO:0030336 negative regulation of cell migration;GO:0071277 cellular response to calcium ion", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P22412-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P24259-1", "uniprot_id": "ANF_PIG", "mass": 16352.0, "length": 150, "protein_name": "Natriuretic peptides A", "gene_name": "NPPA", "organism": "Pig", "refseq_name": "natriuretic peptides A precursor", "refseq_ac": "NP_999425", "gene_names_uniprotkb": "NPPA", "gene_names_refseq": "ANF; ANP; CDD; CDP; NPPA", "protein_names_uniprotkb": "Natriuretic peptides A; ANF 1-33; ANF 3-33; ANF 8-33; ANF; Alpha-atrial natriuretic peptide; Alpha-hANP; Atrial natriuretic factor 1-33; Atrial natriuretic factor 3-33; Atrial natriuretic factor 8-33; Atrial natriuretic factor prohormone; Atrial natriuretic factor; Atrial natriuretic peptide prohormone; Atriopeptigen; Atriopeptin III; Atriopeptin II; Atriopeptin I; CDD 95-126; CDD-ANF; CDD-ANP (95-126); CDD-ANP (99-126); CDD; Cardiodilatin; Cardionatrin; LANH; Long-acting natriuretic hormone; Pro atrial natriuretic factor 1-30; Pro atrial natriuretic factor 31-67; Pro atrial natriuretic factor 79-98; Pro atrial natriuretic factor 99-126; Pro atrial natriuretic peptide 1-30; Pro atrial natriuretic peptide 31-67; Pro atrial natriuretic peptide 79-98; Pro atrial natriuretic peptide 95-126; preproANF; preproANP; preproCDD-ANF; proANF 1-30; proANF 31-67; proANF 79-98; proANF 99-126; proANF; proANP 1-30; proANP 31-67; proANP 79-98; proANP 95-126; proANP", "protein_names_refseq": "atrial natriuretic factor prohormone; atrial natriuretic peptide prohormone; atriopeptigen; cardiodilatin-related peptide; cardiodilatin; natriuretic peptide precursor A; natriuretic peptides A precursor; natriuretic peptides A; preproANF; preproANP; preproCDD-ANF; prepronatriodilatin; proANF; proANP", "tax_id": 9823, "disease": "", "pathway": " (ssc:397496)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "17437340;19361150;20880599;2147477;23539511;25001668;2964562;32663503;6549270;6689515", "class_list": "", "function": "ANP and BNP gene expression differs considerably between cardiac chambers in the first 72 hours of life in healthy piglets, resembling the transition from fetal to neonate circulation. The cardiac gene expression does not explain plasma concentrations., [RefSeq, PubMed]; Arial natriuretic factor (ANF) and N-terminal proANF may be better suited than brain natriuretic peptide as markers of cardiac preload during the development and treatment of acute heart failure., [RefSeq, PubMed]; Atrial natriuretic peptide and vasopressin-presence in the ciliary body of eye in the pig (sus domesticus)., [RefSeq, PubMed]; Effect of insulin on natriuretic peptide gene expression in porcine heart., [RefSeq, PubMed]; Hormone produced in the kidneys that appears to be important for maintaining cardio-renal homeostasis. Mediates vasodilation, natriuresis and diuresis primarily in the renal system, in order to maintain the extracellular fluid volume and control the fluid-electrolyte balance. Specifically binds and stimulates cGMP production by renal transmembrane receptors, likely NPR1. Urodilatin not ANP, may be the natriuretic peptide responsible for the regulation of sodium and water homeostasis in the kidney., [UniProtKB, UniProtKB]; Hormone that plays a key role in mediating cardio-renal homeostasis, and is involved in vascular remodeling and regulating energy metabolism (By similarity). Acts by specifically binding and stimulating NPR1 to produce cGMP, which in turn activates effector proteins, such as PRKG1, that drive various biological responses (By similarity). Regulates vasodilation, natriuresis, diuresis and aldosterone synthesis and is therefore essential for regulating blood pressure, controlling the extracellular fluid volume and maintaining the fluid-electrolyte balance (PubMed:2964562). Also involved in inhibiting cardiac remodeling and cardiac hypertrophy by inducing cardiomyocyte apoptosis and attenuating the growth of cardiomyocytes and fibroblasts (By similarity). Plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus, and thus prevents pregnancy-induced hypertension (By similarity). In adipose tissue, acts in various cGMP- and PKG-dependent pathways to regulate lipid metabolism and energy homeostasis (By similarity). This includes up-regulating lipid metabolism and mitochondrial oxygen utilization by activating the AMP-activated protein kinase (AMPK), and increasing energy expenditure by acting via MAPK11 to promote the UCP1-dependent thermogenesis of brown adipose tissue (By similarity). Binds the clearance receptor NPR3 which removes the hormone from circulation (By similarity)., [UniProtKB, UniProtKB, UniProtKB, PubMed]; May have a role in cardio-renal homeostasis through regulation of diuresis and inhibiting aldosterone synthesis. In vitro, promotes the production of cGMP and induces vasodilation. May promote natriuresis, at least in part, by enhancing prostaglandin E2 synthesis resulting in the inhibition of renal Na+-K+-ATPase. May have a role in potassium excretion but not sodium excretion (natriuresis). Possibly enhances protein excretion in urine by decreasing proximal tubular protein reabsorption., [UniProtKB, UniProtKB]; May have a role in cardio-renal homeostasis through regulation of natriuresis and vasodilation. In vivo promotes natriuresis. In vitro, selectively vasodilates intestinal smooth muscle but not vascular smooth muscle strips., [UniProtKB, UniProtKB]; May have a role in cardio-renal homeostasis through regulation of natriuresis, diuresis, and vasodilation. In vitro, promotes the production of cGMP and induces vasodilation. May promote natriuresis, at least in part, by enhancing prostaglandin E2 synthesis resulting in the inhibition of renal Na+-K+-ATPase. However reports on the involvement of this peptide in mammal blood volume and blood pressure homeostasis are conflicting; according to a report it is not sufficient to activate cGMP and does not inhibit collecting duct transport nor effect diuresis and natriuresis. Appears to bind to specific receptors that are distinct from the receptors bound by the atrial natriuretic and long-acting natriuretic peptides. Possibly functions in protein excretion in urine by maintaining the integrity of the proximal tubules and enhancing protein excretion by decreasing proximal tubular protein reabsorption., [UniProtKB, UniProtKB]; May have a role in cardio-renal homeostasis through regulation of natriuresis, diuresis, vasodilation, and inhibiting aldosterone synthesis. In vitro, promotes the production of cGMP and induces vasodilation. May promote natriuresis, at least in part, by enhancing prostaglandin E2 synthesis resulting in the inhibition of renal Na+-K+-ATPase (By similarity). However reports on the involvement of this peptide in mammal blood volume and blood pressure homeostasis are conflicting; according to a report, in vivo it is not sufficient to activate cGMP and does not inhibit collecting duct transport nor effect diuresis and natriuresis (By similarity). Appears to bind to specific receptors that are distinct from the receptors bound by atrial natriuretic peptide and vessel dilator. Possibly enhances protein excretion in urine by decreasing proximal tubular protein reabsorption (By similarity)., [UniProtKB, UniProtKB, UniProtKB]; May have a role in cardio-renal homeostasis through regulation of regulation of natriuresis and vasodilation. In vivo promotes natriuresis. In vitro, vasodilates intestinal smooth muscle but not smooth muscle strips., [UniProtKB, UniProtKB]; Stimulation of prepubertal granulosa cells with FSH resulted in a moderate expression of ANP. When FSH treatment was followed by LH, the pronounced expression of ANP was observed in all cells., [RefSeq, PubMed]; Up-regulation of ANP and a reduction in a ratio of sarcoplasmic reticulum calcium ATPase 2a and phospholamban in failing myocardium are observed in a porcine model of tachycardia., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005179 hormone activity;GO:0051427 hormone receptor binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005737 cytoplasm;GO:0043204 perikaryon;GO:0042995 cell projection", "go_biological_process": "GO:0006182 cGMP biosynthetic process;GO:0007218 neuropeptide signaling pathway;GO:0008217 regulation of blood pressure;GO:0042311 vasodilation;GO:0007565 female pregnancy", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "P24259-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P24786-1", "uniprot_id": "NTRK3_PIG", "mass": 93130.0, "length": 825, "protein_name": "NT-3 growth factor receptor", "gene_name": "NTRK3", "organism": "Pig", "refseq_name": "NT-3 growth factor receptor precursor", "refseq_ac": "NP_999436", "gene_names_uniprotkb": "NTRK3; TRKC", "gene_names_refseq": "NTRK3; TRKC", "protein_names_uniprotkb": "NT-3 growth factor receptor; 2.7.10.1; GP145-TrkC; Neurotrophic tyrosine kinase receptor type 3; Trk-C; TrkC tyrosine kinase", "protein_names_refseq": "NT-3 growth factor receptor precursor; NT-3 growth factor receptor; gp145-trkC; neurotrophic tyrosine kinase, receptor, type 3; trk-C; trkC tyrosine kinase; tyrosine kinase receptor", "tax_id": 9823, "disease": "", "pathway": " (ssc:397511)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "1653651", "class_list": "", "function": "Receptor tyrosine kinase involved in nervous system and probably heart development. Upon binding of its ligand NTF3/neurotrophin-3, NTRK3 autophosphorylates and activates different signaling pathways, including the phosphatidylinositol 3-kinase/AKT and the MAPK pathways, that control cell survival and differentiation., [UniProtKB, UniProtKB]", "predicted_glycosites": 15, "predicted_n_glycosites": 14, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 15, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0043121 neurotrophin binding;GO:0005524 ATP binding;GO:0004714 transmembrane receptor protein tyrosine kinase activity;GO:0005030 neurotrophin receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0030424 axon;GO:0043235 receptor complex", "go_biological_process": "GO:0007169 cell surface receptor protein tyrosine kinase signaling pathway;GO:0007399 nervous system development;GO:0007507 heart development;GO:0010976 positive regulation of neuron projection development;GO:0030154 cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "P24786-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P31006-1", "uniprot_id": "KGUA_PIG", "mass": 21921.0, "length": 198, "protein_name": "Guanylate kinase", "gene_name": "GUK1", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "GUK1; GUK", "gene_names_refseq": "", "protein_names_uniprotkb": "Guanylate kinase; 2.7.4.8; GMP kinase", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 2, "publication_id_list": "29515371;8097461", "class_list": "", "function": "Catalyzes the phosphorylation of GMP to GDP. Essential enzyme for recycling GMP and indirectly, cyclic GMP (cGMP). Involved in the cGMP metabolism in photoreceptors., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004385 GMP kinase activity;GO:0050145 nucleoside monophosphate kinase activity;GO:0005524 ATP binding", "go_cellular_component": "GO:0005829 cytosol;GO:0001917 photoreceptor inner segment", "go_biological_process": "GO:0006163 purine nucleotide metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "P31006-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P33198-1", "uniprot_id": "IDHP_PIG", "mass": 47526.0, "length": 421, "protein_name": "Isocitrate dehydrogenase [NADP], mitochondrial", "gene_name": "IDH2", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "IDH2", "gene_names_refseq": "", "protein_names_uniprotkb": "Isocitrate dehydrogenase [NADP], mitochondrial; 1.1.1.42; ICD-M; IDH; IDP; NADP(+)-specific ICDH; Oxalosuccinate decarboxylase", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 5, "publication_id_list": "12207025;14512428;1627563;1869531;3624273", "class_list": "", "function": "Plays a role in intermediary metabolism and energy production (PubMed:14512428). It may tightly associate or interact with the pyruvate dehydrogenase complex (PubMed:14512428)., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 3, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0051287 NAD binding;GO:0004450 isocitrate dehydrogenase (NADP+) activity", "go_cellular_component": "GO:0005739 mitochondrion", "go_biological_process": "GO:0006739 NADP+ metabolic process;GO:0006099 tricarboxylic acid cycle;GO:0006102 isocitrate metabolic process;GO:0006103 2-oxoglutarate metabolic process;GO:0006097 glyoxylate cycle", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P33198-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P50578-1", "uniprot_id": "AK1A1_PIG", "mass": 36582.0, "length": 325, "protein_name": "Aldo-keto reductase family 1 member A1", "gene_name": "AKR1A1", "organism": "Pig", "refseq_name": "aldo-keto reductase family 1 member A1", "refseq_ac": "NP_999055", "gene_names_uniprotkb": "AKR1A1; ALR1; ALR", "gene_names_refseq": "AKR1A1; ALR1; Akr1a4", "protein_names_uniprotkb": "Aldo-keto reductase family 1 member A1; 1.1.1.19; 1.1.1.20; 1.1.1.2; 1.1.1.372; 1.1.1.54; 1.6.-.-; Alcohol dehydrogenase [NADP(+)]; Aldehyde reductase; Glucuronate reductase; Glucuronolactone reductase; S-nitroso-CoA reductase; ScorR", "protein_names_refseq": "S-nitroso-CoA reductase; alcohol dehydrogenase; aldehyde reductase; aldo-keto reductase family 1 member A1; glucuronate reductase; glucuronolactone reductase; scorR", "tax_id": 9823, "disease": "", "pathway": " (ssc:396924)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "11306083;12732097;18782556;7484379;7552731;9329083", "class_list": "", "function": "Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols. Displays enzymatic activity towards endogenous metabolites such as aromatic and aliphatic aldehydes, ketones, monosaccharides and bile acids, with a preference for negatively charged substrates, such as glucuronate and succinic semialdehyde (By similarity). Plays an important role in ascorbic acid biosynthesis by catalyzing the reduction of D-glucuronic acid and D-glucurono-gamma-lactone (By similarity). Functions as a detoxifiying enzyme by reducing a range of toxic aldehydes. Reduces methylglyoxal and 3-deoxyglucosone, which are present at elevated levels under hyperglycemic conditions and are cytotoxic. Involved also in the detoxification of lipid-derived aldehydes like acrolein (By similarity). Plays a role in the activation of procarcinogens, such as polycyclic aromatic hydrocarbon trans-dihydrodiols, and in the metabolism of various xenobiotics and drugs (By similarity). Also acts as an inhibitor of protein S-nitrosylation by mediating degradation of S-nitroso-coenzyme A (S-nitroso-CoA), a cofactor required to S-nitrosylate proteins (By similarity). S-nitroso-CoA reductase activity is involved in reprogramming intermediary metabolism in renal proximal tubules, notably by inhibiting protein S-nitrosylation of isoform 2 of PKM (PKM2) (By similarity). Also acts as a S-nitroso-glutathione reductase by catalyzing the NADPH-dependent reduction of S-nitrosoglutathione (By similarity). Displays no reductase activity towards retinoids (PubMed:12732097)., [UniProtKB, PubMed, UniProtKB, UniProtKB]; Structure of ALR1 in ternary complex with NADPH and 3,5-dichlorosalicylic acid is reported as well as the implications for inhibitor binding and selectivity., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "I3L929", "ec_number_list": "", "go_molecular_function": "GO:0004032 aldose reductase (NADPH) activity;GO:0047939 L-glucuronate reductase activity;GO:0047956 glycerol dehydrogenase (NADP+) activity;GO:1990002 methylglyoxal reductase (NADPH) (acetol producing) activity;GO:0047655 allyl-alcohol dehydrogenase activity", "go_cellular_component": "GO:0005829 cytosol;GO:0016324 apical plasma membrane", "go_biological_process": "GO:0006629 lipid metabolic process;GO:0046185 aldehyde catabolic process;GO:0019853 L-ascorbic acid biosynthetic process;GO:0042840 D-glucuronate catabolic process;GO:0110095 cellular detoxification of aldehyde", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P50578-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P53366-1", "uniprot_id": "ADML_PIG", "mass": 20893.0, "length": 188, "protein_name": "Pro-adrenomedullin", "gene_name": "ADM", "organism": "Pig", "refseq_name": "pro-adrenomedullin precursor", "refseq_ac": "NP_999272", "gene_names_uniprotkb": "ADM; AM", "gene_names_refseq": "ADM", "protein_names_uniprotkb": "Pro-adrenomedullin; PAMP; ProAM N-terminal 20 peptide; ProAM-N20", "protein_names_refseq": "pro-adrenomedullin precursor; pro-adrenomedullin", "tax_id": 9823, "disease": "", "pathway": " (ssc:397195); (R-SSC-419812); (R-SSC-9856530)", "pathway_count": 3, "publication_count": 6, "publication_id_list": "20170313;23966326;34104954;8043068;8076689;9305741", "class_list": "", "function": "ADM function is mediated by the CALCRL-RAMP2 and CALCRL-RAMP3 receptor complexes with ADM showing the highest potency for the CALCRL-RAMP2 complex., [UniProtKB, UniProtKB]; Adrenomedullin prevented loss of cerebral autoregulation after fluid percussion injury in a sex-dependent and ERK MAPK-dependent manner, [RefSeq, PubMed]; Adrenomedullin/ADM and proadrenomedullin N-20 terminal peptide/PAMP are peptide hormones that act as potent hypotensive and vasodilatator agents. Numerous actions have been reported most related to the physiologic control of fluid and electrolyte homeostasis., [UniProtKB, UniProtKB]; Data suggest that ADM (adrenomedullin) increases oviductal fluid secretion via chloride secretion by calcium and cAMP signal pathways (not nitric oxide signal pathway) via CGRPR (calcitonin gene-related peptide receptor; not adrenomedullin receptor). Publication Status: Online-Only, [RefSeq, PubMed]; Peptide hormone that act as potent hypotensive and vasodilatator agents by inhibiting catecholamine secretion from sympathetic nerve endings and adrenal chromaffin cells (PubMed:8076689). Acts as a ligand for MRGPRX2 receptor in mast cells (By similarity)., [UniProtKB, PubMed, UniProtKB, PubMed]; Temporal and spatial expression of adrenomedullin and its receptors in the porcine uterus and peri-implantation conceptuses., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005179 hormone activity;GO:0031700 adrenomedullin receptor binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005737 cytoplasm", "go_biological_process": "GO:0001570 vasculogenesis;GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0043116 negative regulation of vascular permeability;GO:0045766 positive regulation of angiogenesis;GO:0010460 positive regulation of heart rate", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P53366-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P53603-1", "uniprot_id": "FTCD_PIG", "mass": 58930.0, "length": 541, "protein_name": "Formimidoyltransferase-cyclodeaminase", "gene_name": "FTCD", "organism": "Pig", "refseq_name": "formimidoyltransferase-cyclodeaminase", "refseq_ac": "NP_999440", "gene_names_uniprotkb": "FTCD", "gene_names_refseq": "FTCD", "protein_names_uniprotkb": "Formimidoyltransferase-cyclodeaminase; FTCD; Formiminotetrahydrofolate cyclodeaminase; Formiminotransferase-cyclodeaminase; Glutamate formiminotransferase; Glutamate formyltransferase", "protein_names_refseq": "formimidoyltransferase-cyclodeaminase; formiminotransferase cyclodeaminase", "tax_id": 9823, "disease": "", "pathway": " (ssc:397517)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "10673422;7901203", "class_list": "", "function": "Binds and promotes bundling of vimentin filaments originating from the Golgi., [UniProtKB, UniProtKB]; Folate-dependent enzyme, that displays both transferase and deaminase activity. Serves to channel one-carbon units from formiminoglutamate to the folate pool., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005542 folic acid binding;GO:0030409 glutamate formimidoyltransferase activity;GO:0030412 formimidoyltetrahydrofolate cyclodeaminase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005829 cytosol;GO:0005814 centriole", "go_biological_process": "GO:0019556 L-histidine catabolic process to glutamate and formamide;GO:0019557 L-histidine catabolic process to glutamate and formate;GO:0006548 L-histidine catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "P53603-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P63153-1", "uniprot_id": "GRP_PIG", "mass": 16002.0, "length": 146, "protein_name": "Gastrin-releasing peptide", "gene_name": "GRP", "organism": "Pig", "refseq_name": "gastrin-releasing peptide precursor", "refseq_ac": "XP_020930961", "gene_names_uniprotkb": "GRP", "gene_names_refseq": "GRP", "protein_names_uniprotkb": "Gastrin-releasing peptide; GRP-10; GRP18-27; GRP", "protein_names_refseq": "gastrin-releasing peptide precursor", "tax_id": 9823, "disease": "", "pathway": " (ssc:102166444); (R-SSC-375276); (R-SSC-381771); (R-SSC-416476)", "pathway_count": 4, "publication_count": 2, "publication_id_list": "496973;6546686", "class_list": "", "function": "Induces an itch response through activation of receptors present on mast cells, triggering mast cell degranulation., [UniProtKB, UniProtKB]; Stimulates the release of gastrin and other gastrointestinal hormones (PubMed:496973). Contributes to the perception of prurient stimuli and to the transmission of itch signals in the spinal cord that promote scratching behavior (By similarity). Contributes primarily to nonhistaminergic itch sensation (By similarity). In one study, shown to act in the amygdala as part of an inhibitory network which inhibits memory specifically related to learned fear (By similarity). In another study, shown to act on vasoactive intestinal peptide (VIP)-expressing cells in the auditory cortex, most likely via extrasynaptic diffusion from local and long-range sources, to mediate disinhibition of glutamatergic cells via VIP cell-specific GRPR signaling which leads to enhanced auditory fear memories (By similarity). Contributes to the regulation of food intake (By similarity). Inhibits voltage-gated sodium channels but enhances voltage-gated potassium channels in hippocampal neurons (By similarity). Induces sighing by acting directly on the pre-Botzinger complex, a cluster of several thousand neurons in the ventrolateral medulla responsible for inspiration during respiratory activity (By similarity)., [UniProtKB, UniProtKB, PubMed, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A287ANW4;P01294", "ec_number_list": "", "go_molecular_function": "GO:0005184 neuropeptide hormone activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0034774 secretory granule lumen;GO:0043005 neuron projection", "go_biological_process": "GO:0051970 negative regulation of transmission of nerve impulse;GO:0007218 neuropeptide signaling pathway;GO:0035176 social behavior;GO:2000987 positive regulation of behavioral fear response;GO:0090277 positive regulation of peptide hormone secretion", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "P63153-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P80041-1", "uniprot_id": "DDC_PIG", "mass": 53936.0, "length": 486, "protein_name": "Aromatic-L-amino-acid decarboxylase", "gene_name": "DDC", "organism": "Pig", "refseq_name": "aromatic-L-amino-acid decarboxylase", "refseq_ac": "NP_999019", "gene_names_uniprotkb": "DDC", "gene_names_refseq": "AADC; DDC", "protein_names_uniprotkb": "Aromatic-L-amino-acid decarboxylase; 4.1.1.28; AADC; DDC; DOPA decarboxylase", "protein_names_refseq": "L-aromatic dopa decarboxylase; aromatic-L-amino-acid decarboxylase", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 4, "publication_id_list": "11685243;18547057;1935935;8670114", "class_list": "", "function": "Catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine and L-5-hydroxytryptophan to serotonin., [UniProtKB, PubMed]; The unusual oxygen-consuming oxidative deamination reaction catalyzed by the pyridoxal 5'-phosphate (PLP) enzyme DOPA decarboxylase (DDC) was here investigated., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0030170 pyridoxal phosphate binding;GO:0004058 aromatic-L-amino-acid decarboxylase activity;GO:0036468 L-dopa decarboxylase activity;GO:0036467 5-hydroxy-L-tryptophan decarboxylase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0042416 dopamine biosynthetic process;GO:0006584 catecholamine metabolic process;GO:0006520 amino acid metabolic process;GO:0042427 serotonin biosynthetic process;GO:0019752 carboxylic acid metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P80041-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P80147-1", "uniprot_id": "GABT_PIG", "mass": 56620.0, "length": 500, "protein_name": "4-aminobutyrate aminotransferase, mitochondrial", "gene_name": "ABAT", "organism": "Pig", "refseq_name": "4-aminobutyrate aminotransferase, mitochondrial", "refseq_ac": "NP_999428", "gene_names_uniprotkb": "ABAT; GABAT", "gene_names_refseq": "ABAT; GABAT", "protein_names_uniprotkb": "4-aminobutyrate aminotransferase, mitochondrial; (S)-3-amino-2-methylpropionate transaminase; 2.6.1.19; 2.6.1.22; GABA aminotransferase; GABA transaminase; GABA-AT; GABA-T; Gamma-amino-N-butyrate transaminase; L-AIBAT", "protein_names_refseq": "(S)-3-amino-2-methylpropionate transaminase; 4-aminobutyrate aminotransferase, mitochondrial; GABA aminotransferase; GABA transaminase; GABA-AT; GABA-T; L-AIBAT; gamma-amino-N-butyrate transaminase", "tax_id": 9823, "disease": "", "pathway": " (ssc:397500); (R-SSC-916853)", "pathway_count": 2, "publication_count": 4, "publication_id_list": "10393538;14534310;1521531;1559966", "class_list": "", "function": "Catalyzes the conversion of gamma-aminobutyrate and L-beta-aminoisobutyrate to succinate semialdehyde and methylmalonate semialdehyde, respectively. Can also convert delta-aminovalerate and beta-alanine., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "P27820", "ec_number_list": "", "go_molecular_function": "GO:0030170 pyridoxal phosphate binding;GO:0042802 identical protein binding;GO:0042803 protein homodimerization activity;GO:0046872 metal ion binding;GO:0051537 2 iron, 2 sulfur cluster binding", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix;GO:0005829 cytosol;GO:0032144 4-aminobutyrate transaminase complex", "go_biological_process": "GO:0050877 nervous system process;GO:0009450 gamma-aminobutyric acid catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P80147-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P80276-1", "uniprot_id": "ALDR_PIG", "mass": 35868.0, "length": 316, "protein_name": "Aldo-keto reductase family 1 member B1", "gene_name": "AKR1B1", "organism": "Pig", "refseq_name": "aldo-keto reductase family 1 member B1", "refseq_ac": "NP_001001539", "gene_names_uniprotkb": "AKR1B1; ALR2", "gene_names_refseq": "AKR1B1; ALR2; AR", "protein_names_uniprotkb": "Aldo-keto reductase family 1 member B1; 1.1.1.21; 1.1.1.300; 1.1.1.372; 1.1.1.54; AR; Aldehyde reductase; Aldose reductase", "protein_names_refseq": "aldehyde reductase; aldo-keto reductase family 1 member B1; aldose reductase", "tax_id": 9823, "disease": "", "pathway": " (ssc:396816)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "15162486;1734286;8281941;8493902;9195881", "class_list": "", "function": "Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols. Displays enzymatic activity towards endogenous metabolites such as aromatic and aliphatic aldehydes, ketones, monosaccharides, bile acids and xenobiotics substrates. It catalyzes the reduction of glucose to sorbitol, the first step of the polyol pathway, an alternative route of glucose metabolism that converts glucose to fructose. This pathway becomes highly active under elevated glucose levels, such as during hyperglycemia. Reduces steroids and their derivatives and prostaglandins. Displays low enzymatic activity toward all-trans-retinal, 9-cis-retinal, and 13-cis-retinal. Catalyzes the reduction of diverse phospholipid aldehydes such as 1-palmitoyl-2-(5-oxovaleroyl)-sn -glycero-3-phosphoethanolamin (POVPC) and related phospholipid aldehydes that are generated from the oxydation of phosphotidylcholine and phosphatdyleethanolamides. Plays a role in detoxifying dietary and lipid-derived unsaturated carbonyls, such as crotonaldehyde, 4-hydroxynonenal, trans-2-hexenal, trans-2,4-hexadienal and their glutathione-conjugates carbonyls (GS-carbonyls)., [UniProtKB, UniProtKB]; Crystal structure analysis and molecular dynamics simulations, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004032 aldose reductase (NADPH) activity;GO:0001758 retinal dehydrogenase (NAD+) activity;GO:0036130 prostaglandin H2 endoperoxidase reductase activity;GO:0052650 all-trans-retinol dehydrogenase (NADP+) activity;GO:0047956 glycerol dehydrogenase (NADP+) activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0006060 sorbitol metabolic process;GO:0001523 retinoid metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P80276-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P81076-1", "uniprot_id": "AIF1_PIG", "mass": 16560.0, "length": 146, "protein_name": "Allograft inflammatory factor 1", "gene_name": "AIF1", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "AIF1", "gene_names_refseq": "", "protein_names_uniprotkb": "Allograft inflammatory factor 1; AIF-1; Daintain", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "9391121", "class_list": "", "function": "Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation (By similarity). Has a dual influence on glucose-induced insulin secretion: inhibition at low concentration and stimulation at high concentrations., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0051015 actin filament binding;GO:0005509 calcium ion binding", "go_cellular_component": "GO:0001891 phagocytic cup;GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005856 cytoskeleton", "go_biological_process": "GO:0006911 phagocytosis, engulfment;GO:0006954 inflammatory response;GO:0090026 positive regulation of monocyte chemotaxis;GO:2000406 positive regulation of T cell migration;GO:0051017 actin filament bundle assembly", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "P81076-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P81649-1", "uniprot_id": "RNAS6_PIG", "mass": 17350.0, "length": 153, "protein_name": "Ribonuclease K3", "gene_name": "RNASE6", "organism": "Pig", "refseq_name": "ribonuclease K3 precursor", "refseq_ac": "NP_001161128", "gene_names_uniprotkb": "RNASE6; RNS6", "gene_names_refseq": "RNASE6; RNS6", "protein_names_uniprotkb": "Ribonuclease K3; 3.1.27.-; RNase K3", "protein_names_refseq": "RNase K3; Ribonuclease K3; ribonuclease A family member k6; ribonuclease K3 precursor; ribonuclease K6; ribonuclease, RNase A family, k6", "tax_id": 9823, "disease": "", "pathway": " (ssc:100312981)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "19247805;31549540;7764367", "class_list": "", "function": "Anaemia was more common in younger piglets with RNASE1 GA genotype. ANG gene polymorphism was associated with the severity of iron deficiency in younger piglets. Varying levels of iron status and red blood cell indices in RNASE6 genotypes presumably resulted from the coupling of genes involved in iron metabolism and expressed in an age-dependent manner., [RefSeq, PubMed]; Ribonuclease which shows a preference for the pyrimidines uridine and cytosine (PubMed:7764367). Has potent antibacterial activity against a range of Gram-positive and Gram-negative bacteria, including P.aeruginosa, A.baumanii, M.luteus, S.aureus, E.faecalis, E.faecium, S.saprophyticus and E.coli (By similarity). Causes loss of bacterial membrane integrity, and also promotes agglutination of Gram-negative bacteria (By similarity). Probably contributes to urinary tract sterility (By similarity). Bactericidal activity is independent of RNase activity (By similarity)., [UniProtKB, UniProtKB, PubMed]; The porcine RNASE6 g. 389C>T polymorphism was significantly associated (P < 0.05) with MCV, MCH and neutrophil percentage (NEI %) measured on 0-day-old pigs., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 3, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 3, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 3, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "D0PSF9", "ec_number_list": "", "go_molecular_function": "GO:0016787 hydrolase activity;GO:0003676 nucleic acid binding;GO:0004519 endonuclease activity;GO:0004540 RNA nuclease activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005764 lysosome", "go_biological_process": "GO:0019731 antibacterial humoral response;GO:0045087 innate immune response;GO:0050829 defense response to Gram-negative bacterium;GO:0050830 defense response to Gram-positive bacterium;GO:0061844 antimicrobial humoral immune response mediated by antimicrobial peptide", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P81649-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P83686-1", "uniprot_id": "NB5R3_PIG", "mass": 30831.0, "length": 272, "protein_name": "NADH-cytochrome b5 reductase 3", "gene_name": "CYB5R3", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "CYB5R3; DIA1", "gene_names_refseq": "", "protein_names_uniprotkb": "NADH-cytochrome b5 reductase 3; 1.6.2.2; B5R; Cytochrome b5 reductase; Diaphorase-1", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 11, "publication_id_list": "10082957;11574067;12459552;16973608;19038;3372498;3967486;7417338;7890048;7893687;8880927", "class_list": "", "function": "Catalyzes the reduction of two molecules of cytochrome b5 using NADH as the electron donor., [UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 19, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0050660 flavin adenine dinucleotide binding;GO:0071949 FAD binding;GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H;GO:0090524 cytochrome-b5 reductase activity, acting on NADH", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005741 mitochondrial outer membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006695 cholesterol biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 1.2, "record_id": "P83686-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q00655-1", "uniprot_id": "KSYK_PIG", "mass": 71620.0, "length": 628, "protein_name": "Tyrosine-protein kinase SYK", "gene_name": "SYK", "organism": "Pig", "refseq_name": "tyrosine-protein kinase SYK", "refseq_ac": "NP_001098422", "gene_names_uniprotkb": "SYK", "gene_names_refseq": "SYK", "protein_names_uniprotkb": "Tyrosine-protein kinase SYK; 2.7.10.2; Spleen tyrosine kinase", "protein_names_refseq": "protein-tyrosine kinase; spleen tyrosine kinase; tyrosine-protein kinase SYK", "tax_id": 9823, "disease": "", "pathway": " (ssc:100125540)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "11226282;12709437;17936247;1874735;7513017;8986718", "class_list": "", "function": "Non-receptor tyrosine kinase which mediates signal transduction downstream of a variety of transmembrane receptors including classical immunoreceptors like the B-cell receptor (BCR). Regulates several biological processes including innate and adaptive immunity, cell adhesion, osteoclast maturation, platelet activation and vascular development. Assembles into signaling complexes with activated receptors at the plasma membrane via interaction between its SH2 domains and the receptor tyrosine-phosphorylated ITAM domains. The association with the receptor can also be indirect and mediated by adapter proteins containing ITAM or partial hemITAM domains. The phosphorylation of the ITAM domains is generally mediated by SRC subfamily kinases upon engagement of the receptor. More rarely signal transduction via SYK could be ITAM-independent. Direct downstream effectors phosphorylated by SYK include DEPTOR, VAV1, PLCG1, PI-3-kinase, LCP2 and BLNK. Initially identified as essential in B-cell receptor (BCR) signaling, it is necessary for the maturation of B-cells most probably at the pro-B to pre-B transition. Activated upon BCR engagement, it phosphorylates and activates BLNK an adapter linking the activated BCR to downstream signaling adapters and effectors. It also phosphorylates and activates PLCG1 and the PKC signaling pathway. It also phosphorylates BTK and regulates its activity in B-cell antigen receptor (BCR)-coupled signaling. In addition to its function downstream of BCR also plays a role in T-cell receptor signaling. Plays also a crucial role in the innate immune response to fungal, bacterial and viral pathogens. It is for instance activated by the membrane lectin CLEC7A. Upon stimulation by fungal proteins, CLEC7A together with SYK activates immune cells inducing the production of ROS. Also activates the inflammasome and NF-kappa-B-mediated transcription of chemokines and cytokines in presence of pathogens. Regulates neutrophil degranulation and phagocytosis through activation of the MAPK signaling cascade. Required for the stimulation of neutrophil phagocytosis by IL15 (By similarity). Also mediates the activation of dendritic cells by cell necrosis stimuli. Also involved in mast cells activation. Involved in interleukin-3/IL3-mediated signaling pathway in basophils (By similarity). Also functions downstream of receptors mediating cell adhesion. Relays for instance, integrin-mediated neutrophils and macrophages activation and P-selectin receptor/SELPG-mediated recruitment of leukocytes to inflammatory loci. Also plays a role in non-immune processes. It is for instance involved in vascular development where it may regulate blood and lymphatic vascular separation. It is also required for osteoclast development and function. Functions in the activation of platelets by collagen, mediating PLCG2 phosphorylation and activation. May be coupled to the collagen receptor by the ITAM domain-containing FCER1G. Also activated by the membrane lectin CLEC1B that is required for activation of platelets by PDPN/podoplanin. Involved in platelet adhesion being activated by ITGB3 engaged by fibrinogen. Together with CEACAM20, enhances production of the cytokine CXCL8/IL-8 via the NFKB pathway and may thus have a role in the intestinal immune response (By similarity)., [UniProtKB, UniProtKB, UniProtKB, PubMed, PubMed, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 29, "reported_mutagensis": 3, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004713 protein tyrosine kinase activity;GO:0004715 non-membrane spanning protein tyrosine kinase activity;GO:0005524 ATP binding", "go_cellular_component": "GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0032009 early phagosome", "go_biological_process": "GO:0002366 leukocyte activation involved in immune response;GO:0002283 neutrophil activation involved in immune response;GO:0002554 serotonin secretion by platelet;GO:0010543 regulation of platelet activation;GO:0038156 interleukin-3-mediated signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q00655-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q007T0-1", "uniprot_id": "SDHB_PIG", "mass": 31586.0, "length": 280, "protein_name": "Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial", "gene_name": "SDHB", "organism": "Pig", "refseq_name": "succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial precursor", "refseq_ac": "NP_001098423", "gene_names_uniprotkb": "SDHB", "gene_names_refseq": "Ip; SDHB", "protein_names_uniprotkb": "Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; 1.1.5.-; 1.3.5.1; Ip; Iron-sulfur subunit of complex II; Malate dehydrogenase [quinone] iron-sulfur subunit", "protein_names_refseq": "Iron-sulfur subunit of complex II; Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; malate dehydrogenase [quinone] iron-sulfur subunit; succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial precursor", "tax_id": 9823, "disease": "", "pathway": " (ssc:414412)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "15989954;16751257;17480203;18360780", "class_list": "", "function": "Iron-sulfur protein (IP) subunit of the succinate dehydrogenase complex (mitochondrial respiratory chain complex II), responsible for transferring electrons from succinate to ubiquinone (coenzyme Q) (PubMed:15989954). SDH also oxidizes malate to the non-canonical enol form of oxaloacetate, enol-oxaloacetate. Enol-oxaloacetate, which is a potent inhibitor of the succinate dehydrogenase activity, is further isomerized into keto-oxaloacetate (By similarity)., [UniProtKB, PubMed, UniProtKB]; The gene sequences of each complex II subunit were measured by RT-PCR. N-terminal sequencing work was performed to identify the mitochondrial targeting signal peptide of each subunit., [RefSeq, PubMed]; Tissue expression analysis indicated that that swine SDHB, SNRPA and CRYBB1 gene were differentially expressed in tissues including fat, lung, muscle, small intestine, kidney, large intestine, spleen and liver, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q0QEX6", "ec_number_list": "", "go_molecular_function": "GO:0009055 electron transfer activity;GO:0046872 metal ion binding;GO:0051538 3 iron, 4 sulfur cluster binding;GO:0051539 4 iron, 4 sulfur cluster binding;GO:0051537 2 iron, 2 sulfur cluster binding", "go_cellular_component": "GO:0005743 mitochondrial inner membrane;GO:0031966 mitochondrial membrane;GO:0045273 respiratory chain complex II (succinate dehydrogenase)", "go_biological_process": "GO:0006099 tricarboxylic acid cycle;GO:0022904 respiratory electron transport chain;GO:0009060 aerobic respiration;GO:0006121 mitochondrial electron transport, succinate to ubiquinone", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q007T0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q02745-1", "uniprot_id": "SIA4A_PIG", "mass": 39769.0, "length": 343, "protein_name": "CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1", "gene_name": "ST3GAL1", "organism": "Pig", "refseq_name": "CMP-N-acetylneuraminate-beta-galactosamide- alpha-2,3-sialyltransferase 1", "refseq_ac": "NP_001004047", "gene_names_uniprotkb": "ST3GAL1; SIAT4A", "gene_names_refseq": "SIAT4A; ST3GAL1", "protein_names_uniprotkb": "CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1; 2.4.3.2; 2.4.3.4; Alpha 2,3-ST 1; Beta-galactoside alpha-2,3-sialyltransferase 1; Gal-NAc6S; Gal-beta-1,3-GalNAc-alpha-2,3-sialyltransferase; Monosialoganglioside sialyltransferase; SIAT4-A; ST3Gal I; ST3GalA.1; ST3GalI; ST3O; Sialyltransferase 4A", "protein_names_refseq": "CMP-N-acetylneuraminate-beta-galactosamide- alpha-2,3-sialyltransferase 1; SIAT4-A; ST3Gal I; ST3GalA.1; ST3GalI; ST3O; alpha 2,3-ST 1; beta-galactoside alpha-2,3-sialyltransferase 1; gal beta-1,3 GalNAc alpha-2,3 sialyltransferase; gal-NAc6S; monosialoganglioside sialyltransferase; sialyltransferase 4A", "tax_id": 9823, "disease": "", "pathway": " (ssc:445537)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "1383214;19820709;21945615;8288606", "class_list": "", "function": "A beta-galactoside alpha2->3 sialyltransferase involved in terminal sialylation of glycoproteins and glycolipids (PubMed:19820709, PubMed:8288606). Catalyzes the transfer of sialic acid (N-acetyl-neuraminic acid; Neu5Ac) from the nucleotide sugar donor CMP-Neu5Ac onto acceptor Galbeta-(1->3)-GalNAc-terminated glycoconjugates through an alpha2-3 linkage (PubMed:19820709, PubMed:8288606). Adds sialic acid to the core 1 O-glycan, Galbeta-(1->3)-GalNAc-O-Ser/Thr, which is a major structure of mucin-type O-glycans (PubMed:19820709, PubMed:8288606). As part of a homeostatic mechanism that regulates CD8-positive T cell numbers, sialylates core 1 O-glycans of T cell glycoproteins, SPN/CD43 and PTPRC/CD45. Prevents premature apoptosis of thymic CD8-positive T cells prior to peripheral emigration, whereas in the secondary lymphoid organs controls the survival of CD8-positive memory T cells generated following a successful immune response (By similarity). Transfers sialic acid to asialofetuin, presumably onto Galbeta-(1->3)-GalNAc-O-Ser (PubMed:8288606). Sialylates GM1a, GA1 and GD1b gangliosides to form GD1a, GM1b and GT1b, respectively (By similarity) (PubMed:8288606)., [UniProtKB, PubMed, UniProtKB, PubMed]; These results identified the core promoter region in the pST3Gal I promoter and demonstrated that Smad-3 binding to the Samd-3 binding site at -1020 is essential for transcriptional activation of pST3Gal I in TGF-beta1-induced PK-15 cells., [RefSeq, PubMed]", "predicted_glycosites": 4, "predicted_n_glycosites": 4, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0047288 beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminide alpha-2,3- sialyltransferase;GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0016020 membrane;GO:0032588 trans-Golgi network membrane;GO:1990675 Golgi medial cisterna membrane;GO:1990676 Golgi trans cisterna membrane", "go_biological_process": "GO:0006054 N-acetylneuraminate metabolic process;GO:0006629 lipid metabolic process;GO:0006487 protein N-linked glycosylation;GO:0097503 sialylation", "synthesized_glycan_count": 881, "hit_score": 0.5, "record_id": "Q02745-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q28943-1", "uniprot_id": "DPYD_PIG", "mass": 111424.0, "length": 1025, "protein_name": "Dihydropyrimidine dehydrogenase [NADP(+)]", "gene_name": "DPYD", "organism": "Pig", "refseq_name": "dihydropyrimidine dehydrogenase [NADP(+)] precursor", "refseq_ac": "NP_999209", "gene_names_uniprotkb": "DPYD", "gene_names_refseq": "DPD; DPYD", "protein_names_uniprotkb": "Dihydropyrimidine dehydrogenase [NADP(+)]; 1.3.1.2; DHPDHase; DPD; Dihydrothymine dehydrogenase; Dihydrouracil dehydrogenase", "protein_names_refseq": "DHPDHase; dihydropyrimidine dehydrogenase [NADP(+)] precursor; dihydrothymine dehydrogenase; dihydrouracil dehydrogenase", "tax_id": 9823, "disease": "", "pathway": " (ssc:397109)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "11179210;11796730;20831907;32516529;8083224;9860876", "class_list": "", "function": "Data show that dihydropyrimidine dehydrogenase residue H673 is required for active site closure, while S670 is important for substrate recognition., [RefSeq, PubMed]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine., [UniProtKB, PubMed, PubMed, PubMed]; Transient-State Analysis of Porcine Dihydropyrimidine Dehydrogenase Reveals Reductive Activation by NADPH., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 7, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0002058 uracil binding;GO:0017113 dihydropyrimidine dehydrogenase (NADP+) activity;GO:0042803 protein homodimerization activity;GO:0046872 metal ion binding;GO:0050660 flavin adenine dinucleotide binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0006210 thymine catabolic process;GO:0006212 uracil catabolic process;GO:0006214 thymidine catabolic process;GO:0019483 beta-alanine biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "Q28943-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q29016-1", "uniprot_id": "ACRBP_PIG", "mass": 60827.0, "length": 539, "protein_name": "Acrosin-binding protein", "gene_name": "ACRBP", "organism": "Pig", "refseq_name": "acrosin-binding protein isoform 1 precursor", "refseq_ac": "XP_003126581", "gene_names_uniprotkb": "ACRBP", "gene_names_refseq": "ACRBP; sp32", "protein_names_uniprotkb": "Acrosin-binding protein; Acrosin-binding protein, 32 kDa form, mature form; Acrosin-binding protein, 60 kDa form; Proacrosin-binding protein sp32; Sp32; p32", "protein_names_refseq": "Acrosin-binding protein; acrosin-binding protein isoform 1 precursor; acrosin-binding protein, 60 kDa form; proacrosin-binding protein sp32", "tax_id": 9823, "disease": "", "pathway": " (ssc:397317)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "15955892;8144514", "class_list": "", "function": "Acrosomal protein that maintains proacrosin (pro-ACR) as an enzymatically inactive zymogen in the acrosome (PubMed:8144514). Involved also in the acrosome formation (By similarity)., [UniProtKB, PubMed, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005576 extracellular region;GO:0001669 acrosomal vesicle;GO:0002080 acrosomal membrane", "go_biological_process": "GO:0009566 fertilization;GO:0048240 sperm capacitation;GO:0001675 acrosome assembly", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q29016-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q29073-1", "uniprot_id": "PTGR1_PIG", "mass": 35762.0, "length": 329, "protein_name": "Prostaglandin reductase 1", "gene_name": "PTGR1", "organism": "Pig", "refseq_name": "prostaglandin reductase 1", "refseq_ac": "NP_999550", "gene_names_uniprotkb": "PTGR1; LTB4DH", "gene_names_refseq": "DIG-1; LTB4DH; PTGR1", "protein_names_uniprotkb": "Prostaglandin reductase 1; 1.3.1.48; 1.3.1.74; 15-oxoprostaglandin 13-reductase; D3T-inducible gene 1 protein; DIG-1; Dithiolethione-inducible gene 1 protein; Leukotriene B4 12-hydroxydehydrogenase; NAD(P)H-dependent alkenal/one oxidoreductase; PRG-1", "protein_names_refseq": "15-oxoprostaglandin 13-reductase; D3T-inducible gene 1 protein; NAD(P)H-dependent alkenal/one oxidoreductase; NADP dependent leukotriene b4 12-hydroxydehydrogenase; NADP-dependent leukotriene B4 12-hydroxydehydrogenase; PRG-1; dithiolethione-inducible gene 1 protein; prostaglandin reductase 1", "tax_id": 9823, "disease": "", "pathway": " (ssc:397678)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "10837478;11688989;8394361;8576264;9461497", "class_list": "", "function": "NAD(P)H-dependent oxidoreductase involved in metabolic inactivation of pro- and anti-inflammatory eicosanoids: prostaglandins (PG), leukotrienes (LT) and lipoxins (LX) (PubMed:10837478, PubMed:11688989, PubMed:8576264, PubMed:9461497). Preferentially uses NADPH over NADH as cofactor (PubMed:9461497). Catalyzes with high efficiency the reduction of the 13,14 double bond of 15-oxoPGs, including 15-oxo-PGE1, 15-oxo-PGE2, 15-oxo-PGF1-alpha and 15-oxo-PGF2-alpha (PubMed:11688989, PubMed:9461497). Catalyzes with lower efficiency the oxidation of the hydroxyl group at C12 of LTB4 and its derivatives, converting them into biologically less active 12-oxo-LTB4 metabolites (PubMed:8394361, PubMed:8576264). Reduces 15-oxo-LXA4 to 13,14 dihydro-15-oxo-LXA4 and may promote neutrophil recruitment at the inflammatory site (PubMed:10837478, PubMed:11688989). Plays a role in metabolic detoxification of alkenals and ketones. Reduces alpha,beta-unsaturated alkenals and ketones, particularly those with medium-chain length, showing highest affinity toward (2E)-decenal and (3E)-3-nonen-2-one (By similarity). May inactivate 4-hydroxy-2-nonenal, a cytotoxic lipid constituent of oxidized low-density lipoprotein particles (By similarity)., [UniProtKB, UniProtKB, UniProtKB, PubMed, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 7, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "O62642", "ec_number_list": "", "go_molecular_function": "GO:0047522 15-oxoprostaglandin 13-reductase [NAD(P)+] activity;GO:0035798 2-alkenal reductase (NADPH) activity;GO:0036185 13-lipoxin reductase activity;GO:0097257 leukotriene B4 12-hydroxy dehydrogenase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0006693 prostaglandin metabolic process;GO:0036102 leukotriene B4 metabolic process;GO:2001302 lipoxin A4 metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "Q29073-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q29122-1", "uniprot_id": "MYO6_PIG", "mass": 144859.0, "length": 1254, "protein_name": "Unconventional myosin-VI", "gene_name": "MYO6", "organism": "Pig", "refseq_name": "unconventional myosin-VI", "refseq_ac": "NP_999186", "gene_names_uniprotkb": "MYO6", "gene_names_refseq": "MYO6", "protein_names_uniprotkb": "Unconventional myosin-VI; Unconventional myosin-6", "protein_names_refseq": "unconventional myosin-6; unconventional myosin-VI; unconventional myosin", "tax_id": 9823, "disease": "", "pathway": " (ssc:397085)", "pathway_count": 1, "publication_count": 13, "publication_id_list": "12682054;15037754;15944696;16917816;19664948;21808051;22940248;25159143;25738229;25751888;29844196;7929586;8022818", "class_list": "", "function": "A myosin VI deafness mutation, D179Y, uncoupled the release of the ATP hydrolysis product, inorganic phosphate (Pi), from dependency on actin binding and destroyed the ability of single dimeric molecules to move processively on actin filaments., [RefSeq, PubMed]; Data suggest that cells direct the movement of vesicles around a cell by altering the relative number of myosin Va from Gallus gallus and myosin VI from Sus scrofa. Publication Status: Online-Only, [RefSeq, PubMed]; Model reveals that myosin VI, unlike plus-end directed myosins, does not use a pure lever arm mechanism, but instead steps with a mechanism analogous to the kinesin neck-linker uncoupling mode, [RefSeq, PubMed]; Myosins are actin-based motor molecules with ATPase activity (By similarity). Unconventional myosins serve in intracellular movements (By similarity). Myosin 6 is a reverse-direction motor protein that moves towards the minus-end of actin filaments (By similarity). Has slow rate of actin-activated ADP release due to weak ATP binding (PubMed:15944696). Functions in a variety of intracellular processes such as vesicular membrane trafficking and cell migration (PubMed:16917816). Required for the structural integrity of the Golgi apparatus via the p53-dependent pro-survival pathway (By similarity). Appears to be involved in a very early step of clathrin-mediated endocytosis in polarized epithelial cells (By similarity). Together with TOM1, mediates delivery of endocytic cargo to autophagosomes thereby promoting autophagosome maturation and driving fusion with lysosomes (By similarity). Links TOM1 with autophagy receptors, such as TAX1BP1; CALCOCO2/NDP52 and OPTN (By similarity). May act as a regulator of F-actin dynamics (PubMed:7929586). As part of the DISP complex, may regulate the association of septins with actin and thereby regulate the actin cytoskeleton (By similarity). May play a role in transporting DAB2 from the plasma membrane to specific cellular targets (By similarity). May play a role in the extension and network organization of neurites (By similarity). Required for structural integrity of inner ear hair cells (By similarity). Required for the correct localization of CLIC5 and RDX at the stereocilium base (By similarity). Modulates RNA polymerase II-dependent transcription (By similarity)., [UniProtKB, UniProtKB, PubMed, UniProtKB, PubMed, PubMed]; Studied the crystal structure of myosin VI, (the pretransition state (PTS)), in particular the recovery stroke of Myosin VI, which was solved at 2.2 A resolution., [RefSeq, PubMed]; The stepping dynamics of single quantum-dot-labeled myoV and myoVI motors linked to a common cargo, was studied., [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 6, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005516 calmodulin binding;GO:0005524 ATP binding;GO:0051015 actin filament binding;GO:0043531 ADP binding;GO:0003774 cytoskeletal motor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005794 Golgi apparatus;GO:0005829 cytosol", "go_biological_process": "GO:0042491 inner ear auditory receptor cell differentiation;GO:0006886 intracellular protein transport;GO:0006897 endocytosis;GO:0007015 actin filament organization;GO:0042472 inner ear morphogenesis", "synthesized_glycan_count": 0, "hit_score": 1.4, "record_id": "Q29122-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q6SA96-1", "uniprot_id": "RS23_PIG", "mass": 15817.0, "length": 143, "protein_name": "Small ribosomal subunit protein uS12", "gene_name": "RPS23", "organism": "Pig", "refseq_name": "small ribosomal subunit protein uS12", "refseq_ac": "NP_998929", "gene_names_uniprotkb": "RPS23", "gene_names_refseq": "RPS23", "protein_names_uniprotkb": "Small ribosomal subunit protein uS12; 40S ribosomal protein S23", "protein_names_refseq": "40S ribosomal protein S23; small ribosomal subunit protein uS12", "tax_id": 9823, "disease": "", "pathway": " (ssc:396638)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "24930395;33384682", "class_list": "", "function": "Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:24930395). The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel. Plays an important role in translational accuracy. Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (By similarity)., [UniProtKB, UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005840 ribosome;GO:0098556 cytoplasmic side of rough endoplasmic reticulum membrane;GO:0032040 small-subunit processome;GO:0022627 cytosolic small ribosomal subunit", "go_biological_process": "GO:0006412 translation;GO:1990145 maintenance of translational fidelity;GO:0002181 cytoplasmic translation;GO:0042274 ribosomal small subunit biogenesis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q6SA96-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q8SPS7-1", "uniprot_id": "HPT_PIG", "mass": 38482.0, "length": 347, "protein_name": "Haptoglobin", "gene_name": "HP", "organism": "Pig", "refseq_name": "haptoglobin precursor", "refseq_ac": "NP_999165", "gene_names_uniprotkb": "HP", "gene_names_refseq": "HP", "protein_names_uniprotkb": "Haptoglobin", "protein_names_refseq": "haptoglobin alpha 1S; haptoglobin precursor; zonulin", "tax_id": 9823, "disease": "", "pathway": " (ssc:397061); (R-SSC-2168880); (R-SSC-6798695)", "pathway_count": 3, "publication_count": 8, "publication_id_list": "12139523;15210076;16438801;17629575;18777092;18931071;22922649;34103548", "class_list": "", "function": "As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidly cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway (By similarity)., [UniProtKB]; Crystal structure of the dimeric porcine haptoglobin-haemoglobin complex determined at 2.9 A resolution, [RefSeq, PubMed]; Evidence of haptoglobin in the porcine female genital tract during oestrous cycle and its effect on in vitro embryo production. Publication Status: Online-Only, [RefSeq, PubMed]; Haptoglobin has a role in oxidative status in piglets undergoing weaning-induced stress, [RefSeq, PubMed]; Presence of haptoglobin alpha 1S subunit is a reponse to respiratory syndrome virus infection., [RefSeq, PubMed]; The haptoglobin was down-regulated with SNPs, [RefSeq, PubMed]; This protein is elevated in porcine postweaning multisystemic wasting syndrome., [RefSeq, PubMed]; This study suggested closer links between the release of haptoglobin, Pig-MAP and monocytes compared to the release of AGP, SAA and transthyretin., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 4, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 4, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 4, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004252 serine-type endopeptidase activity;GO:0016209 antioxidant activity;GO:0030492 hemoglobin binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0072562 blood microparticle", "go_biological_process": "GO:0006953 acute-phase response;GO:0042742 defense response to bacterium;GO:0031638 zymogen activation;GO:0002376 immune system process", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "Q8SPS7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9N0F1-1", "uniprot_id": "ODO2_PIG", "mass": 48977.0, "length": 455, "protein_name": "Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial", "gene_name": "DLST", "organism": "Pig", "refseq_name": "dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial precursor", "refseq_ac": "NP_999562", "gene_names_uniprotkb": "DLST", "gene_names_refseq": "DLST-tv1; DLST", "protein_names_uniprotkb": "Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial; 2-oxoglutarate dehydrogenase complex component E2; 2.3.1.61; Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex; E2K; E2o; OGDC-E2; PE2o", "protein_names_refseq": "2-oxoglutarate dehydrogenase complex component E2; E2K; E2o; OGDC-E2; PE2o; dihydrolipamide succinyl transferase-like protein; dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex; dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial precursor; dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial", "tax_id": 9823, "disease": "", "pathway": " (ssc:397690)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "10806400;37506369", "class_list": "", "function": "Dihydrolipoamide succinyltransferase (E2) component of the 2-oxoglutarate dehydrogenase complex (PubMed:10806400). The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) (PubMed:10806400). The 2-oxoglutarate dehydrogenase complex is mainly active in the mitochondrion (By similarity). A fraction of the 2-oxoglutarate dehydrogenase complex also localizes in the nucleus and is required for lysine succinylation of histones: associates with KAT2A on chromatin and provides succinyl-CoA to histone succinyltransferase KAT2A (By similarity)., [UniProtKB, UniProtKB, PubMed]; MYOD induced lnc-MEG3 promotes porcine satellite cell differentiation via interacting with DLST., [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 7, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004149 dihydrolipoyllysine-residue succinyltransferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix;GO:0045252 oxoglutarate dehydrogenase complex", "go_biological_process": "GO:0006099 tricarboxylic acid cycle;GO:0006103 2-oxoglutarate metabolic process;GO:0006104 succinyl-CoA metabolic process;GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q9N0F1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D0G6S1-1", "uniprot_id": "DCTN6_PIG", "mass": 20681.0, "length": 190, "protein_name": "Dynactin subunit 6", "gene_name": "DCTN6", "organism": "Pig", "refseq_name": "dynactin subunit 6", "refseq_ac": "NP_001161116", "gene_names_uniprotkb": "DCTN6", "gene_names_refseq": "DCTN6", "protein_names_uniprotkb": "Dynactin subunit 6", "protein_names_refseq": "dynactin 6; dynactin subunit 6", "tax_id": 9823, "disease": "", "pathway": " (ssc:100312966); (R-SSC-2132295); (R-SSC-3371497); (R-SSC-6807878)", "pathway_count": 4, "publication_count": 6, "publication_id_list": "25814576;29420470;31597779;32543654;33734450;36071160", "class_list": "", "function": "Part of the dynactin complex that activates the molecular motor dynein for ultra-processive transport along microtubules., [UniProtKB, UniProtKB, UniProtKB, PubMed, PubMed, PubMed, PubMed]; The ability of Classical Swine Fever Virus E2 protein to bind host DCTN6 protein efficiently during infection may play a role in viral virulence. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0070840 dynein complex binding", "go_cellular_component": "GO:0005813 centrosome;GO:0005869 dynactin complex;GO:0000776 kinetochore", "go_biological_process": "GO:0007052 mitotic spindle organization;GO:0007017 microtubule-based process", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "D0G6S1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "A0PFK5-1", "uniprot_id": "CAZA1_PIG", "mass": 33017.0, "length": 286, "protein_name": "F-actin-capping protein subunit alpha-1", "gene_name": "CAPZA1", "organism": "Pig", "refseq_name": "F-actin-capping protein subunit alpha-1", "refseq_ac": "NP_001090923", "gene_names_uniprotkb": "CAPZA1; CP alpha1; Capza", "gene_names_refseq": "CAPZA1; Capza", "protein_names_uniprotkb": "F-actin-capping protein subunit alpha-1", "protein_names_refseq": "CP alpha1; F-actin capping protein alpha 1 subunit; F-actin capping protein subunit alpha 1; F-actin-capping protein subunit alpha-1; capping actin protein of muscle Z-line alpha subunit 1; capping protein (actin filament) muscle Z-line, alpha 1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100037957); (R-SSC-879415)", "pathway_count": 2, "publication_count": 6, "publication_id_list": "17939027;25814576;29420470;30723633;33734450;36071160", "class_list": "", "function": "F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. May play a role in the formation of epithelial cell junctions (By similarity). Forms, with CAPZB, the barbed end of the fast growing ends of actin filaments in the dynactin complex and stabilizes dynactin structure. The dynactin multiprotein complex activates the molecular motor dynein for ultra-processive transport along microtubules (PubMed:25814576, PubMed:29420470, PubMed:33734450, PubMed:36071160)., [UniProtKB, PubMed, PubMed, PubMed, PubMed, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "F6Q4Y6", "ec_number_list": "", "go_molecular_function": "GO:0051015 actin filament binding", "go_cellular_component": "GO:0005829 cytosol;GO:0015629 actin cytoskeleton;GO:0008290 F-actin capping protein complex;GO:0030863 cortical cytoskeleton", "go_biological_process": "GO:0030036 actin cytoskeleton organization;GO:0051016 barbed-end actin filament capping;GO:0007017 microtubule-based process", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "A0PFK5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "D5K8A9-1", "uniprot_id": "SACA1_PIG", "mass": 32239.0, "length": 295, "protein_name": "Sperm acrosome membrane-associated protein 1", "gene_name": "SPACA1", "organism": "Pig", "refseq_name": "sperm acrosome membrane-associated protein 1 precursor", "refseq_ac": "NP_001177176", "gene_names_uniprotkb": "SPACA1", "gene_names_refseq": "SPACA1", "protein_names_uniprotkb": "Sperm acrosome membrane-associated protein 1", "protein_names_refseq": "sperm acrosome membrane-associated protein 1 precursor; sperm acrosome membrane-associated protein 1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100156797)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "18448843;27449406", "class_list": "", "function": "Plays a role in acrosome expansion and establishment of normal sperm morphology during spermatogenesis. Important for male fertility., [UniProtKB, UniProtKB]; This study suggests that the increase of small types of SPACA1 proteins is a valid indicator for occurrence of the acrosomal disintegration arising from the true and false acrosome reactions., [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0002080 acrosomal membrane;GO:0002079 inner acrosomal membrane", "go_biological_process": "GO:0001675 acrosome assembly", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "D5K8A9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1RKB1-1", "uniprot_id": "DRC10_PIG", "mass": 54393.0, "length": 467, "protein_name": "Dynein regulatory complex subunit 10", "gene_name": "DRC10", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "DRC10; IQCD", "gene_names_refseq": "", "protein_names_uniprotkb": "Dynein regulatory complex subunit 10; IQ domain-containing protein D", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (ssc:100525308)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "33139725", "class_list": "", "function": "Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0036064 ciliary basal body", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1RKB1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "I3LDJ9-1", "uniprot_id": "I3LDJ9_PIG", "mass": 22022.0, "length": 202, "protein_name": "BCL2 interacting protein 3", "gene_name": "BNIP3", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "BNIP3", "gene_names_refseq": "", "protein_names_uniprotkb": "BCL2 interacting protein 3", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0042802 identical protein binding", "go_cellular_component": "GO:0031966 mitochondrial membrane;GO:0005634 nucleus;GO:0005635 nuclear envelope;GO:0005741 mitochondrial outer membrane;GO:0005783 endoplasmic reticulum", "go_biological_process": "GO:0043065 positive regulation of apoptotic process;GO:0006915 apoptotic process;GO:0097345 mitochondrial outer membrane permeabilization;GO:0043068 positive regulation of programmed cell death", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "I3LDJ9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P79293-1", "uniprot_id": "MYH7_PIG", "mass": 223298.0, "length": 1935, "protein_name": "Myosin-7", "gene_name": "MYH7B; MYH7", "organism": "Pig", "refseq_name": "myosin-7", "refseq_ac": "NP_999020", "gene_names_uniprotkb": "MYH7B; MYH7; MYH7", "gene_names_refseq": "MYH7", "protein_names_uniprotkb": "Myosin-7; MyHC-beta; MyHC-slow; Myosin heavy chain 7; Myosin heavy chain slow isoform; Myosin heavy chain, cardiac muscle beta isoform", "protein_names_refseq": "beta-myosin heavy chain; myHC-beta; myHC-slow; myosin, heavy polypeptide 7, cardiac muscle, beta; myosin-7", "tax_id": 9823, "disease": "", "pathway": " (ssc:396860)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "23153285;26116789;29685038;32543654;37057868", "class_list": "", "function": "Akirin2 siRNA abolished arginine-induced upregulation of MyHC I., [RefSeq, PubMed]; MicroRNA-27a inhibits porcine type I muscle fibre gene expression by directly targeting peroxisome proliferator-activated receptor-gamma coactivator-1alpha., [RefSeq, PubMed]; Mutation analysis of MYH7 gene revealed an in-frame insertion within exon 30 of MYH7 which was perfectly associated with the disease phenotype and confirmed the dominant inheritance. Publication Status: Online-Only, [RefSeq, PubMed]; Myosin regulatory light chain phosphorylation enhances cardiac beta-myosin in vitro motility under load., [RefSeq, PubMed]; Myosins are actin-based motor molecules with ATPase activity essential for muscle contraction. Forms regular bipolar thick filaments that, together with actin thin filaments, constitute the fundamental contractile unit of skeletal and cardiac muscle., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 8, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9GKR1", "ec_number_list": "", "go_molecular_function": "GO:0005516 calmodulin binding;GO:0005524 ATP binding;GO:0051015 actin filament binding;GO:0000146 microfilament motor activity;GO:0003774 cytoskeletal motor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0030017 sarcomere;GO:0032982 myosin filament;GO:0030016 myofibril;GO:0016460 myosin II complex", "go_biological_process": "GO:0030049 muscle filament sliding;GO:0060048 cardiac muscle contraction;GO:0007512 adult heart development;GO:0031449 regulation of slow-twitch skeletal muscle fiber contraction;GO:0003009 skeletal muscle contraction", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P79293-1", "record_type": "protein" }, { "uniprot_canonical_ac": "O77696-1", "uniprot_id": "AT2A3_PIG", "mass": 109328.0, "length": 999, "protein_name": "Sarcoplasmic/endoplasmic reticulum calcium ATPase 3", "gene_name": "ATP2A3", "organism": "Pig", "refseq_name": "sarcoplasmic/endoplasmic reticulum calcium ATPase 3", "refseq_ac": "XP_020923351", "gene_names_uniprotkb": "ATP2A3", "gene_names_refseq": "ATP2A3_tv1; ATP2A3; SERCA3", "protein_names_uniprotkb": "Sarcoplasmic/endoplasmic reticulum calcium ATPase 3; 7.2.2.10; Calcium pump 3; SERCA3; SR Ca(2+)-ATPase 3", "protein_names_refseq": "ATPase, Ca++ transporting, ubiquitous; SR Ca(2+)-ATPase 3; calcium pump 3; sarcoendoplasmic reticulum calcium ATPase; sarcoplasmic/endoplasmic reticulum calcium ATPase 3", "tax_id": 9823, "disease": "", "pathway": " (ssc:396820); (R-SSC-418359); (R-SSC-5578775); (R-SSC-936837)", "pathway_count": 4, "publication_count": 3, "publication_id_list": "10724327;30723633;32543654", "class_list": "", "function": "Catalyzes the hydrolysis of ATP coupled with the transport of calcium., [UniProtKB, UniProtKB, UniProtKB]; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. Transports calcium ions from the cytosol into the sarcoplasmic/endoplasmic reticulum lumen. Contributes to calcium sequestration involved in muscular excitation/contraction., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A286ZW82;K9IW69", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0016887 ATP hydrolysis activity;GO:0005388 P-type calcium transporter activity;GO:0005246 calcium channel regulator activity", "go_cellular_component": "GO:0016020 membrane;GO:0033017 sarcoplasmic reticulum membrane", "go_biological_process": "GO:0006874 intracellular calcium ion homeostasis;GO:0070588 calcium ion transmembrane transport;GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress;GO:1903515 calcium ion transport from cytosol to endoplasmic reticulum", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "O77696-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SR89-1", "uniprot_id": "F1SR89_PIG", "mass": 52352.0, "length": 463, "protein_name": "Gamma-aminobutyric acid type A receptor subunit alpha5", "gene_name": "GABRA5", "organism": "Pig", "refseq_name": "gamma-aminobutyric acid receptor subunit alpha-5 isoform X1", "refseq_ac": "XP_003121696", "gene_names_uniprotkb": "GABRA5", "gene_names_refseq": "GABRA5", "protein_names_uniprotkb": "Gamma-aminobutyric acid type A receptor subunit alpha5", "protein_names_refseq": "gamma-aminobutyric acid receptor subunit alpha-5 isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100520472); (R-SSC-977443)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A4X1UE43", "ec_number_list": "", "go_molecular_function": "GO:0005254 chloride channel activity;GO:0004890 GABA-A receptor activity;GO:0005230 extracellular ligand-gated monoatomic ion channel activity;GO:0022851 GABA-gated chloride ion channel activity;GO:0099507 ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential", "go_cellular_component": "GO:0045211 postsynaptic membrane;GO:0034707 chloride channel complex;GO:0098794 postsynapse;GO:0044297 cell body;GO:0032590 dendrite membrane", "go_biological_process": "GO:0007214 gamma-aminobutyric acid signaling pathway;GO:0060384 innervation;GO:1902476 chloride transmembrane transport;GO:0060119 inner ear receptor cell development;GO:0090102 cochlea development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SR89-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SI99-1", "uniprot_id": "F1SI99_PIG", "mass": 142108.0, "length": 1296, "protein_name": "Activating molecule in BECN1-regulated autophagy protein 1", "gene_name": "AMBRA1", "organism": "Pig", "refseq_name": "activating molecule in BECN1-regulated autophagy protein 1 isoform X1", "refseq_ac": "XP_020940900", "gene_names_uniprotkb": "AMBRA1", "gene_names_refseq": "AMBRA1", "protein_names_uniprotkb": "Activating molecule in BECN1-regulated autophagy protein 1", "protein_names_refseq": "activating molecule in BECN1-regulated autophagy protein 1 isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100519700); (R-SSC-1632852)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0031625 ubiquitin protein ligase binding;GO:0051020 GTPase binding;GO:0019903 protein phosphatase binding;GO:1990756 ubiquitin-like ligase-substrate adaptor activity;GO:0072542 protein phosphatase activator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005739 mitochondrion;GO:0005783 endoplasmic reticulum;GO:0005829 cytosol;GO:0005856 cytoskeleton", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0007399 nervous system development;GO:0030154 cell differentiation;GO:0006914 autophagy;GO:0010508 positive regulation of autophagy", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SI99-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SUZ2-1", "uniprot_id": "F1SUZ2_PIG", "mass": 191390.0, "length": 1753, "protein_name": "Nuclear pore complex protein Nup98-Nup96", "gene_name": "NUP98", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "NUP98", "gene_names_refseq": "", "protein_names_uniprotkb": "Nuclear pore complex protein Nup98-Nup96", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-141430); (R-SSC-141444); (R-SSC-159227); (R-SSC-159230); (R-SSC-159231); (R-SSC-159236); (R-SSC-1855170); (R-SSC-1855196); (R-SSC-1855229); (R-SSC-191859); (R-SSC-2467813); (R-SSC-2500257); (R-SSC-3108214); (R-SSC-3232142); (R-SSC-3301854); (R-SSC-3371453); (R-SSC-4085377); (R-SSC-4551638); (R-SSC-4570464); (R-SSC-4615885); (R-SSC-5663220); (R-SSC-68877); (R-SSC-9615933); (R-SSC-9648025)", "pathway_count": 24, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. NUP98 and NUP96 are involved in the bidirectional transport across the NPC. May anchor NUP153 and TPR to the NPC. In cooperation with DHX9, plays a role in transcription and alternative splicing activation of a subset of genes. Involved in the localization of DHX9 in discrete intranuclear foci (GLFG-body)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0017056 structural constituent of nuclear pore;GO:0008236 serine-type peptidase activity;GO:0003713 transcription coactivator activity;GO:0003723 RNA binding;GO:0003729 mRNA binding", "go_cellular_component": "GO:0005643 nuclear pore;GO:0005654 nucleoplasm;GO:0031965 nuclear membrane;GO:0031080 nuclear pore outer ring;GO:0044615 nuclear pore nuclear basket", "go_biological_process": "GO:0006508 proteolysis;GO:0015031 protein transport;GO:0051028 mRNA transport;GO:0048026 positive regulation of mRNA splicing, via spliceosome;GO:0051292 nuclear pore complex assembly", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SUZ2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SLE8-1", "uniprot_id": "F1SLE8_PIG", "mass": 57438.0, "length": 512, "protein_name": "Cytochrome P450 26B1", "gene_name": "CYP26B1", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "CYP26B1", "gene_names_refseq": "", "protein_names_uniprotkb": "Cytochrome P450 26B1", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (ssc:100521659); (R-SSC-211916); (R-SSC-5365859)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0004497 monooxygenase activity;GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0008401 retinoic acid 4-hydroxylase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0034653 retinoic acid catabolic process;GO:0010628 positive regulation of gene expression;GO:0071300 cellular response to retinoic acid;GO:0007417 central nervous system development;GO:0006805 xenobiotic metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SLE8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1RTA0-1", "uniprot_id": "F1RTA0_PIG", "mass": 262820.0, "length": 2381, "protein_name": "Voltage-dependent T-type calcium channel subunit alpha", "gene_name": "CACNA1G", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "CACNA1G", "gene_names_refseq": "", "protein_names_uniprotkb": "Voltage-dependent T-type calcium channel subunit alpha", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the `low-voltage activated (LVA)` group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite negative potentials, and a voltage-dependent inactivation. T-type channels serve pacemaking functions in both central neurons and cardiac nodal cells and support calcium signaling in secretory cells and vascular smooth muscle. They may also be involved in the modulation of firing patterns of neurons which is important for information processing as well as in cell growth processes., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008332 low voltage-gated calcium channel activity;GO:0046872 metal ion binding;GO:0097110 scaffold protein binding;GO:0005248 voltage-gated sodium channel activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005891 voltage-gated calcium channel complex;GO:0043005 neuron projection;GO:0001518 voltage-gated sodium channel complex", "go_biological_process": "GO:0070509 calcium ion import;GO:0086010 membrane depolarization during action potential;GO:0045956 positive regulation of calcium ion-dependent exocytosis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1RTA0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "I3LFJ6-1", "uniprot_id": "I3LFJ6_PIG", "mass": 132524.0, "length": 1165, "protein_name": "Leptin receptor", "gene_name": "LEPR", "organism": "Pig", "refseq_name": "leptin receptor isoform X1", "refseq_ac": "XP_020949146", "gene_names_uniprotkb": "LEPR", "gene_names_refseq": "LEPR", "protein_names_uniprotkb": "Leptin receptor; OB receptor", "protein_names_refseq": "leptin receptor isoform X1", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004896 cytokine receptor activity;GO:0017046 peptide hormone binding;GO:0019955 cytokine binding;GO:0038021 leptin receptor activity", "go_cellular_component": "GO:0016323 basolateral plasma membrane;GO:0043235 receptor complex;GO:0009897 external side of plasma membrane", "go_biological_process": "GO:0048731 system development;GO:0033210 leptin-mediated signaling pathway;GO:0001525 angiogenesis;GO:0008284 positive regulation of cell population proliferation;GO:0006909 phagocytosis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "I3LFJ6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P37111-1", "uniprot_id": "ACY1_PIG", "mass": 45347.0, "length": 407, "protein_name": "Aminoacylase-1", "gene_name": "ACY1", "organism": "Pig", "refseq_name": "aminoacylase-1", "refseq_ac": "NP_999061", "gene_names_uniprotkb": "ACY1", "gene_names_refseq": "ACY1", "protein_names_uniprotkb": "Aminoacylase-1; 3.5.1.14; ACY-1; N-acyl-L-amino-acid amidohydrolase", "protein_names_refseq": "ACY-1; N-acyl-L-amino-acid amidohydrolase; N-acylamino acid aminohydrolase (Aminoacylase 1); aminoacylase-1", "tax_id": 9823, "disease": "", "pathway": " (ssc:396930)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "12824065;1284246;1292507;16567407;18341290;32543654", "class_list": "", "function": "Aminoacylase involved in the hydrolysis of N-acetylated and N-formylated amino acids. May act sequentially with APEH in the degradation of N-acylated peptides: APEH first cleaves N-acylaminoacids from N-acylated peptides, then ACY1 further hydrolyzes the N-acylaminoacid into free aminoacid and a carboxylate., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Apo-aminoacylase followed similar rules as Holo-enzyme, which suggested the zinc ion may play more important roles on activity other than structure, [RefSeq, PubMed]; Based on site-directed mutagenesis, homology modeling and substrate docking studies, a revised catalytic mechanism for porcine metalloenzyme aminoacylase 1 has been proposed., [RefSeq, PubMed]; T347S variant of human Acy1 exhibited markedly increased catalytic efficiency against N-benzoylamino acids, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004046 aminoacylase activity;GO:0042802 identical protein binding;GO:0046872 metal ion binding;GO:0008463 formylmethionine deformylase activity;GO:0016787 hydrolase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0070062 extracellular exosome", "go_biological_process": "GO:0006520 amino acid metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P37111-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P50127-1", "uniprot_id": "GGTA1_PIG", "mass": 43764.0, "length": 371, "protein_name": "N-acetyllactosaminide alpha-1,3-galactosyltransferase", "gene_name": "GGTA1", "organism": "Pig", "refseq_name": "N-acetyllactosaminide alpha-1,3-galactosyltransferase isoform 2", "refseq_ac": "NP_001309984", "gene_names_uniprotkb": "GGTA1", "gene_names_refseq": "3GT; GGTA1P; GGTA1; alpha1", "protein_names_uniprotkb": "N-acetyllactosaminide alpha-1,3-galactosyltransferase; 2.4.1.87; Galactosyltransferase; UDP-galactose:beta-D-galactosyl-1,4-N-acetyl-D-glucosaminide alpha-1,3-galactosyltransferase", "protein_names_refseq": "N-acetyllactosaminide alpha-1,3-galactosyltransferase isoform 2; N-acetyllactosaminide alpha-1,3-galactosyltransferase; UDP-galactose:beta-D-galactosyl-1, 4-N-acetyl-D-glucosaminide alpha-1,3-galactosyltransferase; glycoprotein alpha-galactosyltransferase 1 (inactive) ??; glycoprotein alpha-galactosyltransferase 1, pseudogene", "tax_id": 9823, "disease": "", "pathway": " (ssc:396733)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "12672664;15699758;27100221;27830476;28114170;31591751;32543654;32811500;7528726", "class_list": "", "function": "Efficient generation of GGTA1-deficient pigs by electroporation of the CRISPR/Cas9 system into in vitro-fertilized zygotes. Publication Status: Online-Only, [RefSeq, PubMed]; Many waitlisted renal transplant patients have minimal xenoreactive antibody binding to the GGTA1/CMAH/B4GalNT2 knockout pig, but some HLA antibodies in sensitized patients cross-react with class I SLA. Erratum:[Transplantation. 2018 Feb;102(2):e88. doi: 10.1097/TP.0000000000002066. PMID: 29381648], [RefSeq, PubMed]; RNA interference is a potent tool to down modulate alpha-Gal expression and to protect endothelial cells from complement-mediated cytotoxicity., [RefSeq, PubMed]; Silencing the GGTA1, CMAH and B4GalNT2 genes in pigs achieved a significant antigen reduction. Changing the porcine carbohydrate profile effectively mediates human antibody-mediated complement dependent cytoxicity., [RefSeq, PubMed]; Synthesizes the galactose-alpha(1,3)-galactose group by catalyzing the transfer of a galactose residue, with an alpha-1,3 linkage, on terminal lactosaminide (Gal-beta-1,4-GlcNAc-R) disaccharide borne by a glycoprotein or a glycolipid. Preferentially glycosylates proteins, can synthesize galactose-alpha(1,3)-galactose on glycoproteins but cannot synthesize the glycolipid called isogloboside 3 (iGb3) (By similarity)., [UniProtKB]; The peripheral blood mononuclear cells (PBMC) from the transgenic pigs were more resistant to lysis by pooled complement-preserved normal human serum than that from wild type (WT) pig. Accordingly, GGTA1 mutated piglets expressing hCD39 will provide a new organ source for xenotransplantation research, [RefSeq, PubMed]; Transgenic male pigs were produced that possess an alpha alpha-1,3-galactosyltransferase knockout allele and express a randomly inserted human alpha 1,2-fucosylosyltransferase transgene, [RefSeq, PubMed]; Viable pigs after simultaneous inactivation of porcine MHC class I and three xenoreactive antigen genes GGTA1, CMAH and B4GALNT2., [RefSeq, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0046872 metal ion binding;GO:0016757 glycosyltransferase activity;GO:0047276 N-acetyllactosaminide 3-alpha-galactosyltransferase activity", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0031982 vesicle;GO:0032580 Golgi cisterna membrane;GO:0031985 Golgi cisterna", "go_biological_process": "GO:0005975 carbohydrate metabolic process", "synthesized_glycan_count": 43, "hit_score": 1.0, "record_id": "P50127-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1RX59-1", "uniprot_id": "F1RX59_PIG", "mass": 135213.0, "length": 1263, "protein_name": "Poly [ADP-ribose] polymerase", "gene_name": "TNKS", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "TNKS", "gene_names_refseq": "", "protein_names_uniprotkb": "Poly [ADP-ribose] polymerase; 2.4.2.-; PARP", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 4, "predicted_n_glycosites": 0, "predicted_o_glycosites": 4, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0046872 metal ion binding;GO:0016779 nucleotidyltransferase activity;GO:0003950 NAD+ poly-ADP-ribosyltransferase activity;GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005634 nucleus;GO:0000781 chromosome, telomeric region;GO:0005829 cytosol;GO:0097431 mitotic spindle pole", "go_biological_process": "GO:0016055 Wnt signaling pathway;GO:0070213 protein auto-ADP-ribosylation;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0032212 positive regulation of telomere maintenance via telomerase;GO:0070198 protein localization to chromosome, telomeric region", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1RX59-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1RS11-1", "uniprot_id": "F1RS11_PIG", "mass": 67172.0, "length": 592, "protein_name": "Syntaxin-binding protein 1", "gene_name": "STXBP1", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "STXBP1", "gene_names_refseq": "", "protein_names_uniprotkb": "Syntaxin-binding protein 1; Protein unc-18 homolog 1; Protein unc-18 homolog A", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-181429); (R-SSC-181430); (R-SSC-210500); (R-SSC-212676); (R-SSC-264642); (R-SSC-888590)", "pathway_count": 6, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0017075 syntaxin-1 binding", "go_cellular_component": "GO:0005829 cytosol;GO:0016020 membrane;GO:0098978 glutamatergic synapse;GO:0098831 presynaptic active zone cytoplasmic component;GO:0098888 extrinsic component of presynaptic membrane", "go_biological_process": "GO:0015031 protein transport;GO:0016192 vesicle-mediated transport;GO:1903305 regulation of regulated secretory pathway;GO:0002576 platelet degranulation;GO:0006886 intracellular protein transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1RS11-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F2Z4X9-1", "uniprot_id": "F2Z4X9_PIG", "mass": 44141.0, "length": 385, "protein_name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1", "gene_name": "SMARCB1", "organism": "Pig", "refseq_name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 isoform X1", "refseq_ac": "XP_001929472", "gene_names_uniprotkb": "SMARCB1", "gene_names_refseq": "SMARCB1", "protein_names_uniprotkb": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1", "protein_names_refseq": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100154735); (R-SSC-3214858); (R-SSC-8939243); (R-SSC-9933937); (R-SSC-9933939); (R-SSC-9933946)", "pathway_count": 6, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0003713 transcription coactivator activity;GO:0042802 identical protein binding;GO:0030957 Tat protein binding;GO:0002039 p53 binding", "go_cellular_component": "GO:0000228 nuclear chromosome;GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0016514 SWI/SNF complex;GO:0071564 npBAF complex", "go_biological_process": "GO:0006338 chromatin remodeling;GO:0006351 DNA-templated transcription;GO:1902661 positive regulation of glucose mediated signaling pathway;GO:0006357 regulation of transcription by RNA polymerase II;GO:0045944 positive regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F2Z4X9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q0GFF6-1", "uniprot_id": "RXRG_PIG", "mass": 50943.0, "length": 463, "protein_name": "Retinoic acid receptor RXR-gamma", "gene_name": "RXRG", "organism": "Pig", "refseq_name": "retinoic acid receptor RXR-gamma", "refseq_ac": "NP_001123685", "gene_names_uniprotkb": "RXRG; NR2B3", "gene_names_refseq": "NR2B3; RXRG; RXRgamma", "protein_names_uniprotkb": "Retinoic acid receptor RXR-gamma; Nuclear receptor subfamily 2 group B member 3; Retinoid X receptor gamma", "protein_names_refseq": "nuclear receptor subfamily 2 group B member 3; retinoic acid receptor RXR-gamma", "tax_id": 9823, "disease": "", "pathway": " (ssc:445465); (R-SSC-383280)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "15389320;32543654", "class_list": "", "function": "Receptor for retinoic acid that acts as a transcription factor. Forms homo- or heterodimers with retinoic acid receptors (rars) and binds to target response elements in response to their ligands, all-trans or 9-cis retinoic acid, to regulate gene expression in various biological processes., [UniProtKB, UniProtKB, UniProtKB]; Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. The high affinity ligand for RXRs is 9-cis retinoic acid (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q69B31", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0003707 nuclear steroid receptor activity;GO:0004879 nuclear receptor activity;GO:0044323 retinoic acid-responsive element binding;GO:0140693 molecular condensate scaffold activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0090575 RNA polymerase II transcription regulator complex;GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0007399 nervous system development;GO:0030154 cell differentiation;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0048384 retinoic acid receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q0GFF6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1S5G9-1", "uniprot_id": "F1S5G9_PIG", "mass": 158037.0, "length": 1464, "protein_name": "Protein crumbs homolog 1", "gene_name": "CRB1", "organism": "Pig", "refseq_name": "protein crumbs homolog 1", "refseq_ac": "XP_020920141", "gene_names_uniprotkb": "CRB1", "gene_names_refseq": "CRB1", "protein_names_uniprotkb": "Protein crumbs homolog 1", "protein_names_refseq": "protein crumbs homolog 1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100738148)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Plays a role in photoreceptor morphogenesis in the retina. May maintain cell polarization and adhesion., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0005912 adherens junction;GO:0016324 apical plasma membrane;GO:0001917 photoreceptor inner segment;GO:0001750 photoreceptor outer segment", "go_biological_process": "GO:0007163 establishment or maintenance of cell polarity;GO:0051240 positive regulation of multicellular organismal process;GO:0003008 system process;GO:0060042 retina morphogenesis in camera-type eye;GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1S5G9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F2Z5A8-1", "uniprot_id": "F2Z5A8_PIG", "mass": 150508.0, "length": 1298, "protein_name": "Structural maintenance of chromosomes protein", "gene_name": "SMC1A", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "SMC1A", "gene_names_refseq": "", "protein_names_uniprotkb": "Structural maintenance of chromosomes protein", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-2467813); (R-SSC-2468052); (R-SSC-2470946); (R-SSC-2500257); (R-SSC-3108214)", "pathway_count": 5, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0003677 DNA binding;GO:0003682 chromatin binding;GO:0046982 protein heterodimerization activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0008278 cohesin complex;GO:0030893 meiotic cohesin complex;GO:0005634 nucleus;GO:0005829 cytosol", "go_biological_process": "GO:0006281 DNA repair;GO:0051301 cell division;GO:0051321 meiotic cell cycle;GO:0007062 sister chromatid cohesion;GO:0090307 mitotic spindle assembly", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F2Z5A8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1S4A9-1", "uniprot_id": "F1S4A9_PIG", "mass": 102917.0, "length": 927, "protein_name": "Sodium/calcium exchanger 1", "gene_name": "SLC8A3", "organism": "Pig", "refseq_name": "sodium/calcium exchanger 3 isoform X2", "refseq_ac": "XP_001927993", "gene_names_uniprotkb": "SLC8A3", "gene_names_refseq": "SLC8A3", "protein_names_uniprotkb": "Sodium/calcium exchanger 1; Na(+)/Ca(2+)-exchange protein 1; Solute carrier family 8 member 1", "protein_names_refseq": "sodium/calcium exchanger 3 isoform X2", "tax_id": 9823, "disease": "", "pathway": " (ssc:100152101); (R-SSC-418359); (R-SSC-425561); (R-SSC-5578775)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Mediates the exchange of one Ca(2+) ion against three to four Na(+) ions across the cell membrane, and thereby contributes to the regulation of cytoplasmic Ca(2+) levels and Ca(2+)-dependent cellular processes. Contributes to Ca(2+) transport during excitation-contraction coupling in muscle. In a first phase, voltage-gated channels mediate the rapid increase of cytoplasmic Ca(2+) levels due to release of Ca(2+) stores from the endoplasmic reticulum. SLC8A1 mediates the export of Ca(2+) from the cell during the next phase, so that cytoplasmic Ca(2+) levels rapidly return to baseline. Required for normal embryonic heart development and the onset of heart contractions., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005516 calmodulin binding;GO:0046872 metal ion binding;GO:0005432 calcium:sodium antiporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0045202 synapse;GO:0005741 mitochondrial outer membrane;GO:0005829 cytosol;GO:0014069 postsynaptic density", "go_biological_process": "GO:0007154 cell communication;GO:0007612 learning;GO:0007613 memory;GO:0006874 intracellular calcium ion homeostasis;GO:0042552 myelination", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1S4A9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "I3LCZ7-1", "uniprot_id": "I3LCZ7_PIG", "mass": 99267.0, "length": 880, "protein_name": "Dynamin-1", "gene_name": "DNM1", "organism": "Pig", "refseq_name": "dynamin-1 isoform X3", "refseq_ac": "XP_005660529", "gene_names_uniprotkb": "DNM1", "gene_names_refseq": "DNM1", "protein_names_uniprotkb": "Dynamin-1; 3.6.5.5", "protein_names_refseq": "dynamin-1 isoform X3", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-166016); (R-SSC-190873); (R-SSC-196025); (R-SSC-2132295); (R-SSC-8856828)", "pathway_count": 5, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0005546 phosphatidylinositol-4,5-bisphosphate binding;GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding;GO:0008017 microtubule binding", "go_cellular_component": "GO:0001891 phagocytic cup;GO:0005874 microtubule;GO:0005905 clathrin-coated pit;GO:0014069 postsynaptic density;GO:0055037 recycling endosome", "go_biological_process": "GO:0006909 phagocytosis;GO:0006897 endocytosis;GO:0051289 protein homotetramerization;GO:0007032 endosome organization;GO:0006898 receptor-mediated endocytosis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "I3LCZ7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "K7GS96-1", "uniprot_id": "K7GS96_PIG", "mass": 87844.0, "length": 804, "protein_name": "Fibroblast growth factor receptor", "gene_name": "FGFR3", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "FGFR3", "gene_names_refseq": "", "protein_names_uniprotkb": "Fibroblast growth factor receptor; 2.7.10.1", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005007 fibroblast growth factor receptor activity;GO:0005524 ATP binding;GO:0042802 identical protein binding;GO:0017134 fibroblast growth factor binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0030133 transport vesicle", "go_biological_process": "GO:0008283 cell population proliferation;GO:0008284 positive regulation of cell population proliferation;GO:0006915 apoptotic process;GO:0060349 bone morphogenesis;GO:0001503 ossification", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "K7GS96-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1S3I5-1", "uniprot_id": "F1S3I5_PIG", "mass": 189431.0, "length": 1678, "protein_name": "DNA (cytosine-5)-methyltransferase", "gene_name": "DNMT1", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "DNMT1", "gene_names_refseq": "", "protein_names_uniprotkb": "DNA (cytosine-5)-methyltransferase; 2.1.1.37", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-212300); (R-SSC-4655427)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003886 DNA (cytosine-5-)-methyltransferase activity;GO:0003677 DNA binding;GO:0003682 chromatin binding;GO:0008270 zinc ion binding;GO:0008327 methyl-CpG binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005657 replication fork;GO:0005721 pericentric heterochromatin", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0032259 methylation;GO:0044027 negative regulation of gene expression via chromosomal CpG island methylation;GO:0010628 positive regulation of gene expression;GO:1904707 positive regulation of vascular associated smooth muscle cell proliferation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1S3I5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2XQV4-1", "uniprot_id": "ALDH2_PIG", "mass": 56921.0, "length": 521, "protein_name": "Aldehyde dehydrogenase, mitochondrial", "gene_name": "ALDH2", "organism": "Pig", "refseq_name": "aldehyde dehydrogenase, mitochondrial precursor", "refseq_ac": "NP_001038076", "gene_names_uniprotkb": "ALDH2", "gene_names_refseq": "ALDH2", "protein_names_uniprotkb": "Aldehyde dehydrogenase, mitochondrial; 1.2.1.3; ALDH class 2; ALDH-E2", "protein_names_refseq": "ALDH class 2; ALDH-E2; aldehyde dehydrogenase 2 family (mitochondrial); aldehyde dehydrogenase, mitochondrial precursor; aldehyde dehydrogenase, mitochondrial; mitochondrial aldehyde dehydrogenase 2", "tax_id": 9823, "disease": "", "pathway": " (ssc:733685); (R-SSC-380612); (R-SSC-71384); (R-SSC-9837999)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Required for clearance of cellular formaldehyde, a cytotoxic and carcinogenic metabolite that induces DNA damage., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004029 aldehyde dehydrogenase (NAD+) activity;GO:0106435 carboxylesterase activity;GO:0008957 phenylacetaldehyde dehydrogenase (NAD+) activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0006068 ethanol catabolic process;GO:0046185 aldehyde catabolic process;GO:0006067 ethanol metabolic process;GO:1905627 regulation of serotonin biosynthetic process;GO:0018937 nitroglycerin metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q2XQV4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SS17-1", "uniprot_id": "F1SS17_PIG", "mass": 90492.0, "length": 797, "protein_name": "RAS guanyl-releasing protein 1", "gene_name": "RASGRP1", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "RASGRP1", "gene_names_refseq": "", "protein_names_uniprotkb": "RAS guanyl-releasing protein 1; Calcium and DAG-regulated guanine nucleotide exchange factor II; Ras guanyl-releasing protein", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-1169092); (R-SSC-354192); (R-SSC-392517); (R-SSC-5673001)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0005509 calcium ion binding;GO:0005085 guanyl-nucleotide exchange factor activity;GO:0042802 identical protein binding;GO:0031210 phosphatidylcholine binding", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0030154 cell differentiation;GO:0007264 small GTPase-mediated signal transduction;GO:0046579 positive regulation of Ras protein signal transduction;GO:0042110 T cell activation;GO:0042113 B cell activation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SS17-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1RW75-1", "uniprot_id": "F1RW75_PIG", "mass": 331618.0, "length": 2883, "protein_name": "Desmoplakin", "gene_name": "DSP", "organism": "Pig", "refseq_name": "desmoplakin isoform X1", "refseq_ac": "XP_003128216", "gene_names_uniprotkb": "DSP", "gene_names_refseq": "DSP", "protein_names_uniprotkb": "Desmoplakin", "protein_names_refseq": "desmoplakin isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100156744); (R-SSC-351906); (R-SSC-6798695); (R-SSC-6805567); (R-SSC-6809371); (R-SSC-9696264); (R-SSC-9696273)", "pathway_count": 7, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005080 protein kinase C binding;GO:0005198 structural molecule activity;GO:0097110 scaffold protein binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005856 cytoskeleton;GO:0005886 plasma membrane;GO:0014704 intercalated disc;GO:0030057 desmosome", "go_biological_process": "GO:0045104 intermediate filament cytoskeleton organization;GO:0150105 protein localization to cell-cell junction;GO:0086091 regulation of heart rate by cardiac conduction;GO:0030216 keratinocyte differentiation;GO:0098609 cell-cell adhesion", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1RW75-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q28999-1", "uniprot_id": "SAT1_PIG", "mass": 19893.0, "length": 171, "protein_name": "Diamine acetyltransferase 1", "gene_name": "SAT1", "organism": "Pig", "refseq_name": "diamine acetyltransferase 1", "refseq_ac": "NP_999523", "gene_names_uniprotkb": "SAT1; SAT", "gene_names_refseq": "SAT1; SAT", "protein_names_uniprotkb": "Diamine acetyltransferase 1; 2.3.1.57; Polyamine N-acetyltransferase 1; Putrescine acetyltransferase; SSAT-1; SSAT; Spermidine/spermine N(1)-acetyltransferase 1", "protein_names_refseq": "SSAT-1; SSAT; diamine acetyltransferase 1; polyamine N-acetyltransferase 1; putrescine acetyltransferase; spermidine/spermine N(1)-acetyltransferase 1; spermidine/spermine N-acetyltransferase", "tax_id": 9823, "disease": "", "pathway": " (ssc:397645)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "32543654;33002680;8940370", "class_list": "", "function": "Enzyme which catalyzes the acetylation of polyamines. Substrate specificity: norspermidine = spermidine >> spermine > N(1)-acetylspermine. This highly regulated enzyme allows a fine attenuation of the intracellular concentration of polyamines. Also involved in the regulation of polyamine transport out of cells. Also acts on 1,3-diaminopropane and 1,5-diaminopentane., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Polyamine regulation of porcine reproductive and respiratory syndrome virus infection depends on spermidine-spermine acetyltransferase 1., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0042802 identical protein binding;GO:0004145 diamine N-acetyltransferase activity;GO:0008080 N-acetyltransferase activity", "go_cellular_component": "GO:0005829 cytosol;GO:0005737 cytoplasm", "go_biological_process": "GO:0001525 angiogenesis;GO:0006596 polyamine biosynthetic process;GO:0009447 putrescine catabolic process;GO:0032918 spermidine acetylation", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q28999-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SRD1-1", "uniprot_id": "F1SRD1_PIG", "mass": 37922.0, "length": 336, "protein_name": "1-acylglycerol-3-phosphate O-acyltransferase ABHD5", "gene_name": "ABHD5", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "ABHD5", "gene_names_refseq": "", "protein_names_uniprotkb": "1-acylglycerol-3-phosphate O-acyltransferase ABHD5; 2.3.1.51; Abhydrolase domain-containing protein 5", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Coenzyme A-dependent lysophosphatidic acid acyltransferase that catalyzes the transfer of an acyl group on a lysophosphatidic acid. Functions preferentially with 1-oleoyl-lysophosphatidic acid followed by 1-palmitoyl-lysophosphatidic acid, 1-stearoyl-lysophosphatidic acid and 1-arachidonoyl-lysophosphatidic acid as lipid acceptor. Functions preferentially with arachidonoyl-CoA followed by oleoyl-CoA as acyl group donors. Functions in phosphatidic acid biosynthesis. May regulate the cellular storage of triacylglycerol through activation of the phospholipase PNPLA2. Involved in keratinocyte differentiation. Regulates lipid droplet fusion., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "K7PHL7", "ec_number_list": "", "go_molecular_function": "GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity;GO:0042171 lysophosphatidic acid acyltransferase activity;GO:0052689 carboxylic ester hydrolase activity;GO:0004620 phospholipase activity;GO:0060229 lipase activator activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005811 lipid droplet;GO:0005829 cytosol", "go_biological_process": "GO:0006631 fatty acid metabolic process;GO:0030154 cell differentiation;GO:0008654 phospholipid biosynthetic process;GO:0006654 phosphatidic acid biosynthetic process;GO:0010898 positive regulation of triglyceride catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SRD1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1ST81-1", "uniprot_id": "F1ST81_PIG", "mass": 48093.0, "length": 428, "protein_name": "Drebrin-like protein", "gene_name": "DBNL", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "DBNL", "gene_names_refseq": "", "protein_names_uniprotkb": "Drebrin-like protein", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003779 actin binding;GO:0019904 protein domain specific binding;GO:0051015 actin filament binding", "go_cellular_component": "GO:0005769 early endosome;GO:0005886 plasma membrane;GO:0005938 cell cortex;GO:0030027 lamellipodium;GO:0045202 synapse", "go_biological_process": "GO:0048812 neuron projection morphogenesis;GO:0007416 synapse assembly;GO:0098974 postsynaptic actin cytoskeleton organization;GO:0045773 positive regulation of axon extension;GO:0061003 positive regulation of dendritic spine morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1ST81-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SP38-1", "uniprot_id": "F1SP38_PIG", "mass": 161779.0, "length": 1397, "protein_name": "Ribonuclease 3", "gene_name": "DROSHA", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "DROSHA", "gene_names_refseq": "", "protein_names_uniprotkb": "Ribonuclease 3; 3.1.26.3; Ribonuclease III; protein Drosha", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Ribonuclease III double-stranded (ds) RNA-specific endoribonuclease that is involved in the initial step of microRNA (miRNA) biogenesis. Component of the microprocessor complex that is required to process primary miRNA transcripts (pri-miRNAs) to release precursor miRNA (pre-miRNA) in the nucleus. Within the microprocessor complex, DROSHA cleaves the 3' and 5' strands of a stem-loop in pri-miRNAs (processing center 11 bp from the dsRNA-ssRNA junction) to release hairpin-shaped pre-miRNAs that are subsequently cut by the cytoplasmic DICER to generate mature miRNAs. Involved also in pre-rRNA processing. Cleaves double-strand RNA and does not cleave single-strand RNA. Involved in the formation of GW bodies. Plays a role in growth homeostasis in response to autophagy in motor neurons., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0046872 metal ion binding;GO:0004525 ribonuclease III activity;GO:0070878 primary miRNA binding;GO:0042803 protein homodimerization activity;GO:0001530 lipopolysaccharide binding", "go_cellular_component": "GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0098978 glutamatergic synapse;GO:0005634 nucleus;GO:0005654 nucleoplasm", "go_biological_process": "GO:0031054 pre-miRNA processing;GO:0006364 rRNA processing;GO:0010628 positive regulation of gene expression;GO:0050829 defense response to Gram-negative bacterium;GO:0050830 defense response to Gram-positive bacterium", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SP38-1", "record_type": "protein" }, { "uniprot_canonical_ac": "I3LUG7-1", "uniprot_id": "I3LUG7_PIG", "mass": 152500.0, "length": 1362, "protein_name": "DNA mismatch repair protein", "gene_name": "MSH6", "organism": "Pig", "refseq_name": "DNA mismatch repair protein Msh6 isoform X2", "refseq_ac": "XP_003354884", "gene_names_uniprotkb": "MSH6", "gene_names_refseq": "MSH6", "protein_names_uniprotkb": "DNA mismatch repair protein", "protein_names_refseq": "DNA mismatch repair protein Msh6 isoform X2", "tax_id": 9823, "disease": "", "pathway": " (ssc:100624450); (R-SSC-5358565)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Component of the post-replicative DNA mismatch repair system (MMR)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0030983 mismatched DNA binding;GO:0140664 ATP-dependent DNA damage sensor activity;GO:0032357 oxidized purine DNA binding;GO:0032142 single guanine insertion binding", "go_cellular_component": "GO:0005634 nucleus;GO:0032301 MutSalpha complex;GO:0005694 chromosome;GO:0005654 nucleoplasm;GO:0000785 chromatin", "go_biological_process": "GO:0006298 mismatch repair;GO:0051053 negative regulation of DNA metabolic process;GO:0045910 negative regulation of DNA recombination", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "I3LUG7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P80021-1", "uniprot_id": "ATPA_PIG", "mass": 59688.0, "length": 553, "protein_name": "ATP synthase F(1) complex subunit alpha, mitochondrial", "gene_name": "ATP5F1A", "organism": "Pig", "refseq_name": "ATP synthase F(1) complex subunit alpha, mitochondrial", "refseq_ac": "NP_001172071", "gene_names_uniprotkb": "ATP5F1A; ATP5A1; ATP5A2", "gene_names_refseq": "ATP5A1; ATP5A2; ATP5F1A", "protein_names_uniprotkb": "ATP synthase F(1) complex subunit alpha, mitochondrial; ATP synthase F1 subunit alpha; ATP synthase subunit alpha heart isoform, mitochondrial; ATP synthase subunit alpha liver isoform, mitochondrial", "protein_names_refseq": "ATP synthase F(1) complex subunit alpha, mitochondrial; ATP synthase subunit alpha, mitochondrial; ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle; cardiac muscle ATP synthase H+ transporting mitochondrial F1 complex alpha subunit 1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100157880); (R-SSC-163210); (R-SSC-8949613); (R-SSC-9837999)", "pathway_count": 4, "publication_count": 3, "publication_id_list": "1714390;32543654;8672129", "class_list": "", "function": "Produces ATP from ADP in the presence of a proton gradient across the membrane., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Subunit alpha, of the mitochondrial membrane ATP synthase complex (F(1)F(0) ATP synthase or Complex V) that produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. ATP synthase complex consist of a soluble F(1) head domain - the catalytic core - and a membrane F(1) domain - the membrane proton channel. These two domains are linked by a central stalk rotating inside the F(1) region and a stationary peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity). In vivo, can only synthesize ATP although its ATP hydrolase activity can be activated artificially in vitro (By similarity). With the catalytic subunit beta (ATP5F1B), forms the catalytic core in the F(1) domain. Subunit alpha does not bear the catalytic high-affinity ATP-binding sites (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 7, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "B2ZF46;Q29596", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0043531 ADP binding;GO:0046933 proton-transporting ATP synthase activity, rotational mechanism;GO:0043532 angiostatin binding", "go_cellular_component": "GO:0005743 mitochondrial inner membrane;GO:0005886 plasma membrane;GO:0045259 proton-transporting ATP synthase complex", "go_biological_process": "GO:0015986 proton motive force-driven ATP synthesis;GO:0001937 negative regulation of endothelial cell proliferation;GO:0043536 positive regulation of blood vessel endothelial cell migration;GO:0042776 proton motive force-driven mitochondrial ATP synthesis", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "P80021-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1RUE4-1", "uniprot_id": "F1RUE4_PIG", "mass": 100307.0, "length": 906, "protein_name": "Phosphatidylinositol-glycan-specific phospholipase D", "gene_name": "GPLD1", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "GPLD1", "gene_names_refseq": "", "protein_names_uniprotkb": "Phosphatidylinositol-glycan-specific phospholipase D; 3.1.4.50; Glycoprotein phospholipase D; Glycosyl-phosphatidylinositol-specific phospholipase D", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-163125)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Hydrolyzes the inositol phosphate linkage of glycosylphosphatidylinositol (GPI)-anchored membrane proteins, thereby releasing them from the cell surface. Cleaves on the inositol side of the anchor, leaving the phosphate group attached to the membrane. This release of GPI-anchored proteins can modulate diverse biological processes, including the activation of signaling pathways., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004621 glycosylphosphatidylinositol phospholipase D activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005576 extracellular region;GO:0005737 cytoplasm;GO:0031012 extracellular matrix", "go_biological_process": "GO:0006629 lipid metabolic process;GO:0002430 complement receptor mediated signaling pathway;GO:0071401 cellular response to triglyceride;GO:1900076 regulation of cellular response to insulin stimulus;GO:0008285 negative regulation of cell population proliferation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1RUE4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SLZ9-1", "uniprot_id": "F1SLZ9_PIG", "mass": 35919.0, "length": 317, "protein_name": "E3 ubiquitin-protein ligase NRDP1", "gene_name": "RNF41", "organism": "Pig", "refseq_name": "E3 ubiquitin-protein ligase NRDP1", "refseq_ac": "XP_003481664", "gene_names_uniprotkb": "RNF41", "gene_names_refseq": "RNF41", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase NRDP1; 2.3.2.27; RING finger protein 41; RING-type E3 ubiquitin transferase NRDP1", "protein_names_refseq": "E3 ubiquitin-protein ligase NRDP1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100157936); (R-SSC-1358803); (R-SSC-983168)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity;GO:0005135 interleukin-3 receptor binding;GO:0019904 protein domain specific binding;GO:0042802 identical protein binding", "go_cellular_component": "GO:0048471 perinuclear region of cytoplasm;GO:0071782 endoplasmic reticulum tubular network", "go_biological_process": "GO:0000209 protein polyubiquitination;GO:2000379 positive regulation of reactive oxygen species metabolic process;GO:0097191 extrinsic apoptotic signaling pathway;GO:0045732 positive regulation of protein catabolic process;GO:0010498 proteasomal protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SLZ9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "I3L9X2-1", "uniprot_id": "I3L9X2_PIG", "mass": 63496.0, "length": 577, "protein_name": "Insulin-like growth factor 2 mRNA-binding protein 1", "gene_name": "IGF2BP1", "organism": "Pig", "refseq_name": "insulin-like growth factor 2 mRNA-binding protein 1 isoform X1", "refseq_ac": "XP_003358128", "gene_names_uniprotkb": "IGF2BP1", "gene_names_refseq": "IGF2BP1", "protein_names_uniprotkb": "Insulin-like growth factor 2 mRNA-binding protein 1; IGF-II mRNA-binding protein 1; VICKZ family member 1", "protein_names_refseq": "insulin-like growth factor 2 mRNA-binding protein 1 isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100620940)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003730 mRNA 3'-UTR binding;GO:0045182 translation regulator activity;GO:0048027 mRNA 5'-UTR binding;GO:1990247 N6-methyladenosine-containing RNA reader activity", "go_cellular_component": "GO:0005634 nucleus;GO:0030027 lamellipodium;GO:0030426 growth cone;GO:0048471 perinuclear region of cytoplasm;GO:0030175 filopodium", "go_biological_process": "GO:0006417 regulation of translation;GO:0051028 mRNA transport;GO:0010610 regulation of mRNA stability involved in response to stress;GO:0070934 CRD-mediated mRNA stabilization;GO:2000767 positive regulation of cytoplasmic translation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "I3L9X2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P09954-1", "uniprot_id": "CBPA1_PIG", "mass": 47235.0, "length": 419, "protein_name": "Carboxypeptidase A1", "gene_name": "CPA1", "organism": "Pig", "refseq_name": "carboxypeptidase A1 precursor", "refseq_ac": "NP_999409", "gene_names_uniprotkb": "CPA1; CPA", "gene_names_refseq": "CPA1; PCPA1", "protein_names_uniprotkb": "Carboxypeptidase A1; 3.4.17.1", "protein_names_refseq": "carboxypeptidase A1 precursor", "tax_id": 9823, "disease": "", "pathway": " (ssc:397476)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "10092856;1548696;32543654;3801014", "class_list": "", "function": "Carboxypeptidase that catalyzes the release of a C-terminal amino acid, but has little or no action with -Asp, -Glu, -Arg, -Lys or -Pro (By similarity). Catalyzes the conversion of leukotriene C4 to leukotriene F4 via the hydrolysis of an amide bond (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9TV85", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0004181 metallocarboxypeptidase activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0006508 proteolysis;GO:0006691 leukotriene metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P09954-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SHU4-1", "uniprot_id": "F1SHU4_PIG", "mass": 29707.0, "length": 276, "protein_name": "Insulin-induced gene protein", "gene_name": "INSIG1", "organism": "Pig", "refseq_name": "insulin-induced gene 1 protein", "refseq_ac": "NP_001231450", "gene_names_uniprotkb": "INSIG1", "gene_names_refseq": "CL-6; INSIG1", "protein_names_uniprotkb": "Insulin-induced gene protein", "protein_names_refseq": "insulin-induced gene 1 protein; insulin-induced protein INSIG1", "tax_id": 9823, "disease": "", "pathway": " (ssc:403162)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Mediates feedback control of cholesterol synthesis., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008289 lipid binding;GO:0008142 oxysterol binding;GO:0140311 protein sequestering activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane;GO:0005783 endoplasmic reticulum;GO:0032937 SREBP-SCAP-Insig complex", "go_biological_process": "GO:0008203 cholesterol metabolic process;GO:0032869 cellular response to insulin stimulus;GO:0006695 cholesterol biosynthetic process;GO:0042632 cholesterol homeostasis;GO:0045541 negative regulation of cholesterol biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SHU4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1S459-1", "uniprot_id": "F1S459_PIG", "mass": 44313.0, "length": 401, "protein_name": "Telomeric repeat-binding factor 2-interacting protein 1", "gene_name": "TERF2IP", "organism": "Pig", "refseq_name": "telomeric repeat-binding factor 2-interacting protein 1", "refseq_ac": "XP_003126905", "gene_names_uniprotkb": "TERF2IP", "gene_names_refseq": "TERF2IP", "protein_names_uniprotkb": "Telomeric repeat-binding factor 2-interacting protein 1; Repressor/activator protein 1 homolog; TERF2-interacting telomeric protein 1", "protein_names_refseq": "telomeric repeat-binding factor 2-interacting protein 1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100521624); (R-SSC-110330); (R-SSC-110331); (R-SSC-171306); (R-SSC-171319); (R-SSC-174411); (R-SSC-174414); (R-SSC-174417); (R-SSC-174430); (R-SSC-174437); (R-SSC-2559586); (R-SSC-9670095)", "pathway_count": 12, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Acts both as a regulator of telomere function and as a transcription regulator. Involved in the regulation of telomere length and protection as a component of the shelterin complex (telosome). Does not bind DNA directly: recruited to telomeric double-stranded 5'-TTAGGG-3' repeats via its interaction with terf2. Independently of its function in telomeres, also acts as a transcription regulator: recruited to extratelomeric 5'-TTAGGG-3' sites via its association with terf2 or other factors, and regulates gene expression., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0098505 G-rich strand telomeric DNA binding;GO:0042162 telomeric DNA binding;GO:0019902 phosphatase binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0000781 chromosome, telomeric region;GO:0005737 cytoplasm;GO:0070187 shelterin complex", "go_biological_process": "GO:0010833 telomere maintenance via telomere lengthening;GO:0006351 DNA-templated transcription;GO:0006355 regulation of DNA-templated transcription;GO:0032205 negative regulation of telomere maintenance;GO:0035556 intracellular signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1S459-1", "record_type": "protein" }, { "uniprot_canonical_ac": "I3LL31-1", "uniprot_id": "I3LL31_PIG", "mass": 44279.0, "length": 396, "protein_name": "Platelet-derived growth factor C", "gene_name": "PDGFC", "organism": "Pig", "refseq_name": "platelet-derived growth factor C isoform X1", "refseq_ac": "XP_020956944", "gene_names_uniprotkb": "PDGFC", "gene_names_refseq": "PDGFC", "protein_names_uniprotkb": "Platelet-derived growth factor C", "protein_names_refseq": "platelet-derived growth factor C isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100515267); (R-SSC-186797)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008083 growth factor activity;GO:0005161 platelet-derived growth factor receptor binding;GO:0042803 protein homodimerization activity", "go_cellular_component": "GO:0016020 membrane;GO:0005615 extracellular space;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0009986 cell surface", "go_biological_process": "GO:0051781 positive regulation of cell division;GO:0008284 positive regulation of cell population proliferation;GO:0030335 positive regulation of cell migration;GO:0051897 positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction;GO:0070374 positive regulation of ERK1 and ERK2 cascade", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "I3LL31-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SEU3-1", "uniprot_id": "F1SEU3_PIG", "mass": 171023.0, "length": 1528, "protein_name": "Rho GTPase-activating protein 7", "gene_name": "DLC1", "organism": "Pig", "refseq_name": "rho GTPase-activating protein 7 isoform X1", "refseq_ac": "XP_020933373", "gene_names_uniprotkb": "DLC1", "gene_names_refseq": "DLC1", "protein_names_uniprotkb": "Rho GTPase-activating protein 7; Deleted in liver cancer 1 protein homolog; Rho-type GTPase-activating protein 7; START domain-containing protein 12; StAR-related lipid transfer protein 12", "protein_names_refseq": "rho GTPase-activating protein 7 isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100620787); (R-SSC-8980692); (R-SSC-9013026); (R-SSC-9013106); (R-SSC-9013148); (R-SSC-9013149); (R-SSC-9013406)", "pathway_count": 7, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "I3LNZ9", "ec_number_list": "", "go_molecular_function": "GO:0005096 GTPase activator activity;GO:0008289 lipid binding;GO:0042169 SH2 domain binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005925 focal adhesion;GO:0016020 membrane;GO:0005634 nucleus;GO:0005829 cytosol", "go_biological_process": "GO:0007165 signal transduction;GO:0008285 negative regulation of cell population proliferation;GO:0035556 intracellular signal transduction;GO:0030336 negative regulation of cell migration;GO:0030036 actin cytoskeleton organization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SEU3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "I3L812-1", "uniprot_id": "I3L812_PIG", "mass": 62100.0, "length": 572, "protein_name": "Tripeptidyl-peptidase 1", "gene_name": "TPP1", "organism": "Pig", "refseq_name": "tripeptidyl-peptidase 1 isoform X1", "refseq_ac": "XP_003357180", "gene_names_uniprotkb": "TPP1", "gene_names_refseq": "TPP1", "protein_names_uniprotkb": "Tripeptidyl-peptidase 1; 3.4.14.9; Tripeptidyl aminopeptidase; Tripeptidyl-peptidase I", "protein_names_refseq": "tripeptidyl-peptidase 1 isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100623352)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Lysosomal serine protease with tripeptidyl-peptidase I activity. May act as a non-specific lysosomal peptidase which generates tripeptides from the breakdown products produced by lysosomal proteinases. Requires substrates with an unsubstituted N-terminus., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004252 serine-type endopeptidase activity;GO:0046872 metal ion binding;GO:0008240 tripeptidyl-peptidase activity;GO:0004175 endopeptidase activity;GO:0035727 lysophosphatidic acid binding", "go_cellular_component": "GO:0005764 lysosome;GO:0005794 Golgi apparatus;GO:0045121 membrane raft;GO:0055037 recycling endosome", "go_biological_process": "GO:0006508 proteolysis;GO:0030855 epithelial cell differentiation;GO:0043171 peptide catabolic process;GO:0007417 central nervous system development;GO:0070198 protein localization to chromosome, telomeric region", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "I3L812-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1RZL4-1", "uniprot_id": "F1RZL4_PIG", "mass": 90512.0, "length": 819, "protein_name": "ADAM metallopeptidase domain 9", "gene_name": "ADAM9", "organism": "Pig", "refseq_name": "disintegrin and metalloproteinase domain-containing protein 9 isoform X1", "refseq_ac": "XP_001925699", "gene_names_uniprotkb": "ADAM9", "gene_names_refseq": "ADAM9", "protein_names_uniprotkb": "ADAM metallopeptidase domain 9", "protein_names_refseq": "disintegrin and metalloproteinase domain-containing protein 9 isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:397344)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004222 metalloendopeptidase activity;GO:0046872 metal ion binding;GO:0005178 integrin binding;GO:0017124 SH3 domain binding;GO:0005518 collagen binding", "go_cellular_component": "GO:0016020 membrane;GO:0005615 extracellular space;GO:0005886 plasma membrane", "go_biological_process": "GO:0006508 proteolysis;GO:0006509 membrane protein ectodomain proteolysis;GO:0007229 integrin-mediated signaling pathway;GO:0034612 response to tumor necrosis factor;GO:0042117 monocyte activation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1RZL4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "I3LMD8-1", "uniprot_id": "I3LMD8_PIG", "mass": 272269.0, "length": 2460, "protein_name": "Tyrosine-protein phosphatase non-receptor type 13", "gene_name": "PTPN13", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "PTPN13", "gene_names_refseq": "", "protein_names_uniprotkb": "Tyrosine-protein phosphatase non-receptor type 13; 3.1.3.48", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-1660499); (R-SSC-9696264); (R-SSC-9696270); (R-SSC-9696273)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Regulates negatively FAS-induced apoptosis and NGFR-mediated pro-apoptotic signaling., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Tyrosine phosphatase which negatively regulates FAS-induced apoptosis and NGFR-mediated pro-apoptotic signaling. May regulate phosphoinositide 3-kinase (PI3K) signaling through dephosphorylation of PIK3R2., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004725 protein tyrosine phosphatase activity;GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005856 cytoskeleton;GO:0030027 lamellipodium;GO:0005886 plasma membrane", "go_biological_process": "GO:0051896 regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction;GO:1904890 negative regulation of excitatory synapse assembly", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "I3LMD8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1S8X7-1", "uniprot_id": "F1S8X7_PIG", "mass": 54065.0, "length": 479, "protein_name": "Phosphatidylinositol 4-kinase type 2", "gene_name": "PI4K2A", "organism": "Pig", "refseq_name": "phosphatidylinositol 4-kinase type 2-alpha", "refseq_ac": "XP_001929069", "gene_names_uniprotkb": "PI4K2A", "gene_names_refseq": "PI4K2A", "protein_names_uniprotkb": "Phosphatidylinositol 4-kinase type 2; 2.7.1.67", "protein_names_refseq": "phosphatidylinositol 4-kinase type 2-alpha", "tax_id": 9823, "disease": "", "pathway": " (ssc:100156818); (R-SSC-1660499); (R-SSC-1660514); (R-SSC-1660516)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0004430 1-phosphatidylinositol 4-kinase activity;GO:0035651 AP-3 adaptor complex binding", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005768 endosome;GO:0005794 Golgi apparatus;GO:0030425 dendrite;GO:0043204 perikaryon", "go_biological_process": "GO:0046854 phosphatidylinositol phosphate biosynthetic process;GO:0007032 endosome organization;GO:0007030 Golgi organization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1S8X7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q29214-1", "uniprot_id": "RLA0_PIG", "mass": 34359.0, "length": 318, "protein_name": "Large ribosomal subunit protein uL10", "gene_name": "RPLP0", "organism": "Pig", "refseq_name": "large ribosomal subunit protein uL10", "refseq_ac": "NP_001092068", "gene_names_uniprotkb": "RPLP0", "gene_names_refseq": "RPLP0", "protein_names_uniprotkb": "Large ribosomal subunit protein uL10; 60S acidic ribosomal protein P0; 60S ribosomal protein L10E", "protein_names_refseq": "60S acidic ribosomal protein P0; 60S ribosomal protein L10E; L10E; large ribosomal subunit protein uL10; ribosomal phosphoprotein large PO subunit", "tax_id": 9823, "disease": "", "pathway": " (ssc:100049695)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "17469782;32543654;8672129", "class_list": "", "function": "Ribosomal protein P0 is the functional equivalent of E.coli protein L10., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A5X2G5", "ec_number_list": "", "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0014069 postsynaptic density;GO:0036464 cytoplasmic ribonucleoprotein granule;GO:1990904 ribonucleoprotein complex", "go_biological_process": "GO:0042254 ribosome biogenesis", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q29214-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SM35-1", "uniprot_id": "F1SM35_PIG", "mass": 144474.0, "length": 1256, "protein_name": "Phospholipid-transporting ATPase", "gene_name": "ATP8B1", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "ATP8B1", "gene_names_refseq": "", "protein_names_uniprotkb": "Phospholipid-transporting ATPase; 7.6.2.1", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-936837)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0090554 phosphatidylcholine floppase activity;GO:0090556 phosphatidylserine floppase activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0005886 plasma membrane;GO:0016020 membrane;GO:0012505 endomembrane system", "go_biological_process": "GO:0015914 phospholipid transport;GO:0045892 negative regulation of DNA-templated transcription;GO:0045332 phospholipid translocation;GO:0006855 xenobiotic transmembrane transport;GO:0007030 Golgi organization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SM35-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SH88-1", "uniprot_id": "F1SH88_PIG", "mass": 70907.0, "length": 632, "protein_name": "Rac GTPase-activating protein 1", "gene_name": "RACGAP1", "organism": "Pig", "refseq_name": "rac GTPase-activating protein 1 isoform X1", "refseq_ac": "XP_020947292", "gene_names_uniprotkb": "RACGAP1", "gene_names_refseq": "RACGAP1", "protein_names_uniprotkb": "Rac GTPase-activating protein 1; Male germ cell RacGap", "protein_names_refseq": "rac GTPase-activating protein 1 isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100517651); (R-SSC-2132295); (R-SSC-6811434); (R-SSC-8980692); (R-SSC-9013026); (R-SSC-9013106); (R-SSC-9013148); (R-SSC-9013149); (R-SSC-9013404); (R-SSC-9013423); (R-SSC-983189)", "pathway_count": 11, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005096 GTPase activator activity;GO:0008270 zinc ion binding;GO:0008289 lipid binding;GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding;GO:0008017 microtubule binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005819 spindle;GO:0001669 acrosomal vesicle;GO:0032154 cleavage furrow;GO:0030496 midbody", "go_biological_process": "GO:0006811 monoatomic ion transport;GO:0007165 signal transduction;GO:0007283 spermatogenesis;GO:0030154 cell differentiation;GO:0051301 cell division", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SH88-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SLW1-1", "uniprot_id": "F1SLW1_PIG", "mass": 105872.0, "length": 957, "protein_name": "Calsyntenin-3", "gene_name": "CLSTN3", "organism": "Pig", "refseq_name": "calsyntenin-3 isoform X2", "refseq_ac": "XP_003126564", "gene_names_uniprotkb": "CLSTN3", "gene_names_refseq": "CLSTN3", "protein_names_uniprotkb": "Calsyntenin-3", "protein_names_refseq": "calsyntenin-3 isoform X2", "tax_id": 9823, "disease": "", "pathway": " (ssc:100511695)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Postsynaptic adhesion molecule that binds to presynaptic neurexins to mediate both excitatory and inhibitory synapse formation. Promotes synapse development by acting as a cell adhesion molecule at the postsynaptic membrane, which associates with both neurexin-alpha and neurexin-beta proteins at the presynaptic membrane. Regulates the balance between excitatory and inhibitory synapses by inhibiting formation of excitatory parallel-fiber synapses and promoting formation of inhibitory synapses in the same neuron. May also be involved in ascorbate (vitamin C) uptake via its interaction with SLC23A2/SVCT2. Complex formation with APBA2 and APP, stabilizes APP metabolism and enhances APBA2-mediated suppression of beta-APP40 secretion, due to the retardation of intracellular APP maturation., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005509 calcium ion binding;GO:0098632 cell-cell adhesion mediator activity;GO:0042043 neurexin family protein binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0000139 Golgi membrane;GO:0045211 postsynaptic membrane;GO:0005789 endoplasmic reticulum membrane;GO:0043005 neuron projection", "go_biological_process": "GO:0007155 cell adhesion;GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules;GO:0051965 positive regulation of synapse assembly;GO:0050806 positive regulation of synaptic transmission;GO:1905606 regulation of presynapse assembly", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SLW1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "I3LR44-1", "uniprot_id": "I3LR44_PIG", "mass": 51815.0, "length": 465, "protein_name": "Tubulin gamma chain", "gene_name": "TUBG1", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "TUBG1", "gene_names_refseq": "", "protein_names_uniprotkb": "Tubulin gamma chain", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Tubulin is the major constituent of microtubules, protein filaments consisting of alpha- and beta-tubulin heterodimers. Gamma-tubulin is a key component of the gamma-tubulin ring complex (gTuRC) which mediates microtubule nucleation. The gTuRC regulates the minus-end nucleation of alpha-beta tubulin heterodimers that grow into microtubule protafilaments, a critical step in centrosome duplication and spindle formation., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005525 GTP binding;GO:0042802 identical protein binding;GO:0140490 microtubule nucleator activity", "go_cellular_component": "GO:0005813 centrosome;GO:0005874 microtubule;GO:0000930 gamma-tubulin complex;GO:0000794 condensed nuclear chromosome;GO:0005634 nucleus", "go_biological_process": "GO:0007020 microtubule nucleation;GO:0031122 cytoplasmic microtubule organization;GO:0000278 mitotic cell cycle;GO:0007052 mitotic spindle organization;GO:0000070 mitotic sister chromatid segregation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "I3LR44-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F2Z5I8-1", "uniprot_id": "F2Z5I8_PIG", "mass": 27432.0, "length": 242, "protein_name": "small monomeric GTPase", "gene_name": "RAB8A", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "RAB8A", "gene_names_refseq": "", "protein_names_uniprotkb": "small monomeric GTPase; 3.6.5.2", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-2565942); (R-SSC-5620912); (R-SSC-5620916); (R-SSC-8854214); (R-SSC-8876198)", "pathway_count": 5, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005525 GTP binding;GO:0003925 G protein activity;GO:0003924 GTPase activity;GO:0019003 GDP binding;GO:0031489 myosin V binding", "go_cellular_component": "GO:0016020 membrane;GO:0005886 plasma membrane;GO:0030670 phagocytic vesicle membrane;GO:0010008 endosome membrane;GO:0005768 endosome", "go_biological_process": "GO:0015031 protein transport;GO:0098876 vesicle-mediated transport to the plasma membrane;GO:0048210 Golgi vesicle fusion to target membrane;GO:0098969 neurotransmitter receptor transport to postsynaptic membrane;GO:0010506 regulation of autophagy", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F2Z5I8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SK84-1", "uniprot_id": "F1SK84_PIG", "mass": 101343.0, "length": 904, "protein_name": "DEAD/H-box helicase 11", "gene_name": "DDX11", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "DDX11", "gene_names_refseq": "", "protein_names_uniprotkb": "DEAD/H-box helicase 11", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0003723 RNA binding;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0003678 DNA helicase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0000922 spindle pole;GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005813 centrosome", "go_biological_process": "GO:0006139 nucleobase-containing compound metabolic process;GO:0006974 DNA damage response;GO:0072719 cellular response to cisplatin;GO:0072711 cellular response to hydroxyurea;GO:0045876 positive regulation of sister chromatid cohesion", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SK84-1", "record_type": "protein" }, { "uniprot_canonical_ac": "I3LHP5-1", "uniprot_id": "I3LHP5_PIG", "mass": 72631.0, "length": 647, "protein_name": "LIM domain kinase 1", "gene_name": "LIMK1", "organism": "Pig", "refseq_name": "LIM domain kinase 1 isoform X1", "refseq_ac": "XP_020941994", "gene_names_uniprotkb": "LIMK1", "gene_names_refseq": "LIMK1", "protein_names_uniprotkb": "LIM domain kinase 1; 2.7.11.1", "protein_names_refseq": "LIM domain kinase 1 isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100627618); (R-SSC-2029482); (R-SSC-399954); (R-SSC-5627123)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Serine/threonine-protein kinase that plays an essential role in the regulation of actin filament dynamics. Acts downstream of several Rho family GTPase signal transduction pathways. Activated by upstream kinases including ROCK1, PAK1 and PAK4, which phosphorylate LIMK1 on a threonine residue located in its activation loop. LIMK1 subsequently phosphorylates and inactivates the actin binding/depolymerizing factors cofilin-1/CFL1, cofilin-2/CFL2 and destrin/DSTN, thereby preventing the cleavage of filamentous actin (F-actin), and stabilizing the actin cytoskeleton. In this way LIMK1 regulates several actin-dependent biological processes including cell motility, cell cycle progression, and differentiation. Phosphorylates TPPP on serine residues, thereby promoting microtubule disassembly. Stimulates axonal outgrowth and may be involved in brain development., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0031072 heat shock protein binding;GO:0031625 ubiquitin protein ligase binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005856 cytoskeleton;GO:0098978 glutamatergic synapse;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0030036 actin cytoskeleton organization;GO:0051496 positive regulation of stress fiber assembly", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "I3LHP5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P55204-1", "uniprot_id": "GUC2C_PIG", "mass": 123220.0, "length": 1073, "protein_name": "Guanylyl cyclase C", "gene_name": "GUCY2C", "organism": "Pig", "refseq_name": "guanylyl cyclase C precursor", "refseq_ac": "NP_999270", "gene_names_uniprotkb": "GUCY2C; GUC2C", "gene_names_refseq": "GUCY2C", "protein_names_uniprotkb": "Guanylyl cyclase C; 4.6.1.2; GC-C; Heat-stable enterotoxin receptor; Intestinal guanylate cyclase; STA receptor", "protein_names_refseq": "GC-C; STA receptor; guanylate cyclase 2C (heat stable enterotoxin receptor); guanylyl cyclase C precursor; guanylyl cyclase C; heat-stable enterotoxin receptor; intestinal guanylate cyclase", "tax_id": 9823, "disease": "", "pathway": " (ssc:397193); (R-SSC-8935690)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "32543654;7968686", "class_list": "", "function": "Guanylyl cyclase that catalyzes synthesis of cyclic GMP (cGMP) from GTP., [UniProtKB, UniProtKB]", "predicted_glycosites": 7, "predicted_n_glycosites": 7, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 7, "binding_glycan_count": 0, "secondary_ac_list": "Q29050", "ec_number_list": "", "go_molecular_function": "GO:0004383 guanylate cyclase activity;GO:0004672 protein kinase activity;GO:0005524 ATP binding;GO:0005525 GTP binding;GO:0001653 peptide receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006182 cGMP biosynthetic process;GO:0035556 intracellular signal transduction;GO:0007168 receptor guanylyl cyclase signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "P55204-1", "record_type": "protein" }, { "uniprot_canonical_ac": "I3LJN2-1", "uniprot_id": "I3LJN2_PIG", "mass": 89053.0, "length": 791, "protein_name": "Diacylglycerol kinase", "gene_name": "DGKG", "organism": "Pig", "refseq_name": "diacylglycerol kinase gamma isoform X1", "refseq_ac": "XP_020925662", "gene_names_uniprotkb": "DGKG", "gene_names_refseq": "DGKG", "protein_names_uniprotkb": "Diacylglycerol kinase; 2.7.1.107; DAG kinase", "protein_names_refseq": "diacylglycerol kinase gamma isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100623595); (R-SSC-114508)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Diacylglycerol kinase that converts diacylglycerol/DAG into phosphatidic acid/phosphatidate/PA and regulates the respective levels of these two bioactive lipids. Thereby, acts as a central switch between the signaling pathways activated by these second messengers with different cellular targets and opposite effects in numerous biological processes. Has no apparent specificity with regard to the acyl compositions of diacylglycerol. Specifically expressed in the cerebellum where it controls the level of diacylglycerol which in turn regulates the activity of protein kinase C gamma. Through protein kinase C gamma, indirectly regulates the dendritic development of Purkinje cells, cerebellar long term depression and ultimately cerebellar motor coordination., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004143 ATP-dependent diacylglycerol kinase activity;GO:0005524 ATP binding;GO:0008270 zinc ion binding;GO:0005509 calcium ion binding;GO:0008289 lipid binding", "go_cellular_component": "GO:0005829 cytosol;GO:0005856 cytoskeleton;GO:0016020 membrane;GO:0005886 plasma membrane", "go_biological_process": "GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway;GO:0046486 glycerolipid metabolic process;GO:0046339 diacylglycerol metabolic process;GO:0046834 lipid phosphorylation;GO:0006654 phosphatidic acid biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "I3LJN2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "I3LCQ9-1", "uniprot_id": "I3LCQ9_PIG", "mass": 21656.0, "length": 189, "protein_name": "small monomeric GTPase", "gene_name": "KRAS", "organism": "Pig", "refseq_name": "GTPase KRas isoform X1", "refseq_ac": "XP_005653208", "gene_names_uniprotkb": "KRAS", "gene_names_refseq": "KRAS", "protein_names_uniprotkb": "small monomeric GTPase; 3.6.5.2", "protein_names_refseq": "GTPase KRas isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100518251); (R-SSC-1169092); (R-SSC-1250347); (R-SSC-1433557); (R-SSC-171007); (R-SSC-179812); (R-SSC-180336); (R-SSC-186763); (R-SSC-1963640); (R-SSC-210993); (R-SSC-2179392); (R-SSC-2424491); (R-SSC-2871796); (R-SSC-375165); (R-SSC-5218921); (R-SSC-5654688); (R-SSC-5654693); (R-SSC-5654699); (R-SSC-5654700); (R-SSC-5654704); (R-SSC-5654706); (R-SSC-5654712); (R-SSC-5654719); (R-SSC-5658442); (R-SSC-5673000); (R-SSC-5673001); (R-SSC-5674135); (R-SSC-5675221); (R-SSC-8849471); (R-SSC-8851805); (R-SSC-9607240); (R-SSC-9634635); (R-SSC-9648002); (R-SSC-9674555)", "pathway_count": 34, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8D1PH72", "ec_number_list": "", "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0003925 G protein activity;GO:0044877 protein-containing complex binding;GO:0043495 protein-membrane adaptor activity", "go_cellular_component": "GO:0016020 membrane;GO:0005886 plasma membrane;GO:0005829 cytosol;GO:0009898 cytoplasmic side of plasma membrane", "go_biological_process": "GO:0007165 signal transduction;GO:0008284 positive regulation of cell population proliferation;GO:0010628 positive regulation of gene expression;GO:0007265 Ras protein signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "I3LCQ9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1STI4-1", "uniprot_id": "F1STI4_PIG", "mass": 73366.0, "length": 643, "protein_name": "Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR2", "gene_name": "MTMR2", "organism": "Pig", "refseq_name": "myotubularin-related protein 2 isoform X1", "refseq_ac": "XP_003129845", "gene_names_uniprotkb": "MTMR2", "gene_names_refseq": "MTMR2", "protein_names_uniprotkb": "Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR2; 3.1.3.95; Myotubularin-related protein 2; Phosphatidylinositol-3-phosphate phosphatase", "protein_names_refseq": "myotubularin-related protein 2 isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100518140); (R-SSC-1483248); (R-SSC-1660516); (R-SSC-1660517)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Lipid phosphatase that specifically dephosphorylates the D-3 position of phosphatidylinositol 3-phosphate and phosphatidylinositol 3,5-bisphosphate, generating phosphatidylinositol and phosphatidylinositol 5-phosphate. Regulates the level of these phosphoinositides critical for various biological processes including autophagy initiation and autophagosome maturation., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity;GO:0042802 identical protein binding;GO:0004438 phosphatidylinositol-3-phosphate phosphatase activity", "go_cellular_component": "GO:0005768 endosome;GO:0031901 early endosome membrane;GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0006629 lipid metabolic process;GO:0060304 regulation of phosphatidylinositol dephosphorylation;GO:0046856 phosphatidylinositol dephosphorylation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1STI4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SFD1-1", "uniprot_id": "F1SFD1_PIG", "mass": 125412.0, "length": 1138, "protein_name": "Tyrosine-protein kinase receptor Tie-1", "gene_name": "TIE1", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "TIE1", "gene_names_refseq": "", "protein_names_uniprotkb": "Tyrosine-protein kinase receptor Tie-1; 2.7.10.1", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Transmembrane tyrosine-protein kinase that may modulate TEK/TIE2 activity and contribute to the regulation of angiogenesis., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0004714 transmembrane receptor protein tyrosine kinase activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0043235 receptor complex", "go_biological_process": "GO:0001525 angiogenesis;GO:0007169 cell surface receptor protein tyrosine kinase signaling pathway;GO:0045766 positive regulation of angiogenesis;GO:0032526 response to retinoic acid;GO:0003180 aortic valve morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SFD1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F2Z5Q6-1", "uniprot_id": "F2Z5Q6_PIG", "mass": 28681.0, "length": 249, "protein_name": "40S ribosomal protein S6", "gene_name": "DENND4C; RPS6", "organism": "Pig", "refseq_name": "40S ribosomal protein S6 isoform X1", "refseq_ac": "XP_003121938", "gene_names_uniprotkb": "DENND4C; RPS6; RPS6", "gene_names_refseq": "RPS6", "protein_names_uniprotkb": "40S ribosomal protein S6", "protein_names_refseq": "40S ribosomal protein S6 isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100038023)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005840 ribosome;GO:1990904 ribonucleoprotein complex;GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "GO:0006412 translation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F2Z5Q6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1ST39-1", "uniprot_id": "F1ST39_PIG", "mass": 73707.0, "length": 667, "protein_name": "FMR1 autosomal homolog 2", "gene_name": "FXR2", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "FXR2", "gene_names_refseq": "", "protein_names_uniprotkb": "FMR1 autosomal homolog 2", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003729 mRNA binding;GO:0042803 protein homodimerization activity;GO:0046982 protein heterodimerization activity;GO:0003730 mRNA 3'-UTR binding;GO:0045182 translation regulator activity", "go_cellular_component": "GO:0036464 cytoplasmic ribonucleoprotein granule;GO:0005634 nucleus;GO:0005829 cytosol;GO:0043005 neuron projection;GO:0010494 cytoplasmic stress granule", "go_biological_process": "GO:0006417 regulation of translation;GO:0043488 regulation of mRNA stability;GO:0045727 positive regulation of translation;GO:0048513 animal organ development;GO:0048170 positive regulation of long-term neuronal synaptic plasticity", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1ST39-1", "record_type": "protein" }, { "uniprot_canonical_ac": "I3LE68-1", "uniprot_id": "I3LE68_PIG", "mass": 32442.0, "length": 292, "protein_name": "Tissue factor", "gene_name": "F3", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "F3", "gene_names_refseq": "", "protein_names_uniprotkb": "Tissue factor; TF", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-9769735); (R-SSC-9769739)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0002020 protease binding;GO:0004252 serine-type endopeptidase activity;GO:0005543 phospholipid binding;GO:0004896 cytokine receptor activity", "go_cellular_component": "GO:0016020 membrane;GO:0005615 extracellular space;GO:0005886 plasma membrane;GO:0031012 extracellular matrix;GO:0009897 external side of plasma membrane", "go_biological_process": "GO:0007596 blood coagulation;GO:0045766 positive regulation of angiogenesis;GO:0001938 positive regulation of endothelial cell proliferation;GO:0032008 positive regulation of TOR signaling;GO:0002543 activation of blood coagulation via clotting cascade", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "I3LE68-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1RZP9-1", "uniprot_id": "F1RZP9_PIG", "mass": 123778.0, "length": 1122, "protein_name": "[F-actin]-monooxygenase MICAL1", "gene_name": "MICAL1", "organism": "Pig", "refseq_name": "F-actin-methionine sulfoxide oxidase MICAL1 isoform X1", "refseq_ac": "XP_020946618", "gene_names_uniprotkb": "MICAL1", "gene_names_refseq": "MICAL1", "protein_names_uniprotkb": "[F-actin]-monooxygenase MICAL1; 1.14.13.225; 1.6.3.1; Molecule interacting with CasL protein 1", "protein_names_refseq": "F-actin-methionine sulfoxide oxidase MICAL1 isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100153346); (R-SSC-983231)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 4, "predicted_n_glycosites": 0, "predicted_o_glycosites": 4, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003779 actin binding;GO:0046872 metal ion binding;GO:0071949 FAD binding;GO:0016174 NAD(P)H oxidase H2O2-forming activity;GO:0120501 F-actin monooxygenase activity", "go_cellular_component": "GO:0005856 cytoskeleton;GO:0010008 endosome membrane;GO:0030496 midbody;GO:0120025 plasma membrane bounded cell projection;GO:0005829 cytosol", "go_biological_process": "GO:0030042 actin filament depolymerization;GO:0043066 negative regulation of apoptotic process;GO:0051017 actin filament bundle assembly;GO:1903305 regulation of regulated secretory pathway;GO:0019417 sulfur oxidation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1RZP9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SJ69-1", "uniprot_id": "F1SJ69_PIG", "mass": 145188.0, "length": 1274, "protein_name": "Paired amphipathic helix protein Sin3a", "gene_name": "SIN3A", "organism": "Pig", "refseq_name": "paired amphipathic helix protein Sin3a", "refseq_ac": "XP_003482286", "gene_names_uniprotkb": "SIN3A", "gene_names_refseq": "SIN3A", "protein_names_uniprotkb": "Paired amphipathic helix protein Sin3a; Histone deacetylase complex subunit Sin3a; Transcriptional corepressor Sin3a", "protein_names_refseq": "paired amphipathic helix protein Sin3a", "tax_id": 9823, "disease": "", "pathway": " (ssc:100621221); (R-SSC-3899300); (R-SSC-400206); (R-SSC-8936459); (R-SSC-9022692); (R-SSC-9824594); (R-SSC-9825892)", "pathway_count": 7, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Acts as a transcriptional repressor. Corepressor for REST. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Also interacts with MXD1-MAX heterodimers to repress transcription by tethering SIN3A to DNA. Acts cooperatively with OGT to repress transcription in parallel with histone deacetylation. Involved in the control of the circadian rhythms. Required for the transcriptional repression of circadian target genes, such as PER1, mediated by the large PER complex through histone deacetylation. Cooperates with FOXK1 to regulate cell cycle progression probably by repressing cell cycle inhibitor genes expression. Required for cortical neuron differentiation and callosal axon elongation., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "A0A4X1TUT9", "ec_number_list": "", "go_molecular_function": "GO:0003714 transcription corepressor activity;GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding;GO:0003677 DNA binding;GO:0003682 chromatin binding;GO:0140416 transcription regulator inhibitor activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005694 chromosome;GO:0032991 protein-containing complex;GO:0017053 transcription repressor complex", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0048511 rhythmic process;GO:0045666 positive regulation of neuron differentiation;GO:1900181 negative regulation of protein localization to nucleus", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SJ69-1", "record_type": "protein" }, { "uniprot_canonical_ac": "I3LU37-1", "uniprot_id": "I3LU37_PIG", "mass": 161467.0, "length": 1442, "protein_name": "Death-associated protein kinase 1", "gene_name": "DAPK1", "organism": "Pig", "refseq_name": "death-associated protein kinase 1 isoform X1", "refseq_ac": "XP_020920265", "gene_names_uniprotkb": "DAPK1", "gene_names_refseq": "DAPK1", "protein_names_uniprotkb": "Death-associated protein kinase 1; 2.7.11.1", "protein_names_refseq": "death-associated protein kinase 1 isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100516103)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0005516 calmodulin binding;GO:0005525 GTP binding;GO:0042802 identical protein binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0043226 organelle;GO:0098978 glutamatergic synapse;GO:0005886 plasma membrane;GO:0014069 postsynaptic density", "go_biological_process": "GO:0007165 signal transduction;GO:0045087 innate immune response;GO:0006915 apoptotic process;GO:0071345 cellular response to cytokine stimulus;GO:0006417 regulation of translation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "I3LU37-1", "record_type": "protein" }, { "uniprot_canonical_ac": "K7GMN7-1", "uniprot_id": "K7GMN7_PIG", "mass": 123198.0, "length": 1128, "protein_name": "Zinc finger E-box-binding homeobox 1", "gene_name": "ZEB1", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "ZEB1", "gene_names_refseq": "", "protein_names_uniprotkb": "Zinc finger E-box-binding homeobox 1; Transcription factor 8", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-9764725)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0003700 DNA-binding transcription factor activity;GO:0008270 zinc ion binding;GO:0003682 chromatin binding;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005730 nucleolus", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0045666 positive regulation of neuron differentiation;GO:0007417 central nervous system development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "K7GMN7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3YLA6-1", "uniprot_id": "SRSF1_PIG", "mass": 27745.0, "length": 248, "protein_name": "Serine/arginine-rich splicing factor 1", "gene_name": "SRSF1", "organism": "Pig", "refseq_name": "serine/arginine-rich splicing factor 1", "refseq_ac": "NP_001033096", "gene_names_uniprotkb": "SRSF1; SFRS1", "gene_names_refseq": "SFRS1; SRSF1", "protein_names_uniprotkb": "Serine/arginine-rich splicing factor 1; Splicing factor, arginine/serine-rich 1", "protein_names_refseq": "serine/arginine-rich splicing factor 1; splicing factor arginine/serine-rich 1; splicing factor, arginine/serine-rich 1 (splicing factor 2, alternate splicing factor)", "tax_id": 9823, "disease": "", "pathway": " (ssc:654327); (R-SSC-159236); (R-SSC-72163); (R-SSC-72165); (R-SSC-72187); (R-SSC-72203); (R-SSC-9770562)", "pathway_count": 7, "publication_count": 2, "publication_id_list": "16293136;32543654", "class_list": "", "function": "Plays a role in preventing exon skipping, ensuring the accuracy of splicing and regulating alternative splicing. Interacts with other spliceosomal components, via the RS domains, to form a bridge between the 5'- and 3'-splice site binding components, U1 snRNP and U2AF. Can stimulate binding of U1 snRNP to a 5'-splice site-containing pre-mRNA. Binds to purine-rich RNA sequences, either the octamer, 5'-RGAAGAAC-3' (r=A or G) or the decamers, AGGACAGAGC/AGGACGAAGC. Binds preferentially to the 5'-CGAGGCG-3' motif in vitro. Three copies of the octamer constitute a powerful splicing enhancer in vitro, the ASF/SF2 splicing enhancer (ASE) which can specifically activate ASE-dependent splicing. May function as export adapter involved in mRNA nuclear export through the TAP/NXF1 pathway (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 11, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding;GO:0003729 mRNA binding;GO:0044547 DNA topoisomerase binding;GO:0050733 RS domain binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0016607 nuclear speck;GO:0005681 spliceosomal complex", "go_biological_process": "GO:0043484 regulation of RNA splicing;GO:0000381 regulation of alternative mRNA splicing, via spliceosome;GO:0000395 mRNA 5'-splice site recognition;GO:0048255 mRNA stabilization;GO:0034504 protein localization to nucleus", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q3YLA6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "I3LK23-1", "uniprot_id": "I3LK23_PIG", "mass": 37481.0, "length": 339, "protein_name": "Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase", "gene_name": "B3GAT3", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "B3GAT3", "gene_names_refseq": "", "protein_names_uniprotkb": "Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase; 2.4.1.135", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-1971475)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 1, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0046872 metal ion binding;GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity;GO:0072542 protein phosphatase activator activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005801 cis-Golgi network", "go_biological_process": "GO:0006024 glycosaminoglycan biosynthetic process;GO:0090316 positive regulation of intracellular protein transport;GO:0005975 carbohydrate metabolic process;GO:0050650 chondroitin sulfate proteoglycan biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "I3LK23-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q4PS85-1", "uniprot_id": "MYOZ1_PIG", "mass": 31667.0, "length": 298, "protein_name": "Myozenin-1", "gene_name": "MYOZ1", "organism": "Pig", "refseq_name": "myozenin-1", "refseq_ac": "NP_001020393", "gene_names_uniprotkb": "MYOZ1", "gene_names_refseq": "MYOZ1; Myozenin-1", "protein_names_uniprotkb": "Myozenin-1; Calcineurin-interacting protein 2; Calsarcin-2", "protein_names_refseq": "calcineurin-interacting protein-2; calsarcin-2; myozenin-1", "tax_id": 9823, "disease": "", "pathway": " (ssc:574060)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "16574346;32543654", "class_list": "", "function": "Myozenins may serve as intracellular binding proteins involved in linking Z-disk proteins such as alpha-actinin, gamma-filamin, TCAP/telethonin, LDB3/ZASP and localizing calcineurin signaling to the sarcomere. Plays an important role in the modulation of calcineurin signaling. May play a role in myofibrillogenesis (By similarity)., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q1AG04", "ec_number_list": "", "go_molecular_function": "GO:0004865 protein serine/threonine phosphatase inhibitor activity;GO:0051373 FATZ binding;GO:0042805 actinin binding;GO:0140693 molecular condensate scaffold activity", "go_cellular_component": "GO:0005634 nucleus;GO:0015629 actin cytoskeleton;GO:0030018 Z disc;GO:0031143 pseudopodium", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0070885 negative regulation of calcineurin-NFAT signaling cascade;GO:0045214 sarcomere organization;GO:0042060 wound healing;GO:0007519 skeletal muscle tissue development", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q4PS85-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q4FAT7-1", "uniprot_id": "BGLR_PIG", "mass": 74710.0, "length": 652, "protein_name": "Beta-glucuronidase", "gene_name": "GUSB", "organism": "Pig", "refseq_name": "beta-glucuronidase precursor", "refseq_ac": "NP_001116593", "gene_names_uniprotkb": "GUSB", "gene_names_refseq": "GUSB", "protein_names_uniprotkb": "Beta-glucuronidase; 3.2.1.31", "protein_names_refseq": "beta-glucuronidase precursor; beta-glucuronidase", "tax_id": 9823, "disease": "", "pathway": " (ssc:100144519); (R-SSC-2024101); (R-SSC-2160916); (R-SSC-6798695)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Plays an important role in the degradation of dermatan and keratan sulfates., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005102 signaling receptor binding;GO:0019904 protein domain specific binding;GO:0030246 carbohydrate binding;GO:0004566 beta-glucuronidase activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005783 endoplasmic reticulum;GO:0043202 lysosomal lumen;GO:0005764 lysosome", "go_biological_process": "GO:0005975 carbohydrate metabolic process;GO:0030207 chondroitin sulfate proteoglycan catabolic process;GO:0030200 heparan sulfate proteoglycan catabolic process;GO:0030214 hyaluronan catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q4FAT7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "I3L828-1", "uniprot_id": "I3L828_PIG", "mass": 33766.0, "length": 321, "protein_name": "SHOX homeobox 2", "gene_name": "SHOX2", "organism": "Pig", "refseq_name": "short stature homeobox protein 2", "refseq_ac": "NP_001230281", "gene_names_uniprotkb": "SHOX2", "gene_names_refseq": "SHOX2", "protein_names_uniprotkb": "SHOX homeobox 2", "protein_names_refseq": "short stature homeobox 2; short stature homeobox protein 2", "tax_id": 9823, "disease": "", "pathway": " (ssc:100628206)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A5G2RCZ0", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:1990837 sequence-specific double-stranded DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0060931 sinoatrial node cell development;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006357 regulation of transcription by RNA polymerase II;GO:0050772 positive regulation of axonogenesis;GO:0048743 positive regulation of skeletal muscle fiber development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "I3L828-1", "record_type": "protein" }, { "uniprot_canonical_ac": "I3L5W6-1", "uniprot_id": "I3L5W6_PIG", "mass": 56474.0, "length": 520, "protein_name": "Wilms tumor protein homolog", "gene_name": "WT1", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "WT1", "gene_names_refseq": "", "protein_names_uniprotkb": "Wilms tumor protein homolog", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Transcription factor that plays an important role in cellular development and cell survival. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'. Regulates the expression of numerous target genes, including EPO. Plays an essential role for development of the urogenital system. It has a tumor suppressor as well as an oncogenic role in tumor formation. Function may be isoform-specific: isoforms lacking the KTS motif may act as transcription factors. Isoforms containing the KTS motif may bind mRNA and play a role in mRNA metabolism or splicing. Isoform 1 has lower affinity for DNA, and can bind RNA., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0003723 RNA binding;GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005737 cytoplasm;GO:0016607 nuclear speck;GO:0005634 nucleus;GO:0005829 cytosol", "go_biological_process": "GO:0072359 circulatory system development;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0072078 nephron tubule morphogenesis;GO:0072013 glomus development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "I3L5W6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P62197-1", "uniprot_id": "PRS8_PIG", "mass": 45626.0, "length": 406, "protein_name": "26S proteasome regulatory subunit 8", "gene_name": "PSMC5", "organism": "Pig", "refseq_name": "26S proteasome regulatory subunit 8", "refseq_ac": "NP_999148", "gene_names_uniprotkb": "PSMC5", "gene_names_refseq": "PSMC5; TBP10", "protein_names_uniprotkb": "26S proteasome regulatory subunit 8; 26S proteasome AAA-ATPase subunit RPT6; Proteasome 26S subunit ATPase 5; Proteasome subunit p45; TBP10; Tat-binding protein homolog 10; p45/SUG", "protein_names_refseq": "26S protease regulatory subunit 8; 26S protease subunit; 26S proteasome AAA-ATPase subunit RPT6; 26S proteasome regulatory subunit 8; PSMC5 subunit; TAT-binding protein homolog 10; Tat-binding protein 10; p45/SUG; proteasome subunit p45", "tax_id": 9823, "disease": "", "pathway": " (ssc:397043)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "12042320;32543654;8833236", "class_list": "", "function": "Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC5 belongs to the heterohexameric ring of AAA (ATPases associated with diverse cellular activities) proteins that unfolds ubiquitinated target proteins that are concurrently translocated into a proteolytic chamber and degraded into peptides., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "O35051;P47210;P52915;P52916", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0140296 general transcription initiation factor binding;GO:0031531 thyrotropin-releasing hormone receptor binding;GO:0140297 DNA-binding transcription factor binding", "go_cellular_component": "GO:0022624 proteasome accessory complex;GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005886 plasma membrane", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "P62197-1", "record_type": "protein" }, { "uniprot_canonical_ac": "K7GKY8-1", "uniprot_id": "K7GKY8_PIG", "mass": 117315.0, "length": 1068, "protein_name": "Histone deacetylase", "gene_name": "HDAC9", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "HDAC9", "gene_names_refseq": "", "protein_names_uniprotkb": "Histone deacetylase; 3.5.1.98", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-350054)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0046872 metal ion binding;GO:0141221 histone deacetylase activity, hydrolytic mechanism;GO:0042826 histone deacetylase binding;GO:0005080 protein kinase C binding;GO:0004407 histone deacetylase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005667 transcription regulator complex;GO:0000118 histone deacetylase complex", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0032869 cellular response to insulin stimulus;GO:0042632 cholesterol homeostasis;GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "K7GKY8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "K7GLC0-1", "uniprot_id": "K7GLC0_PIG", "mass": 51263.0, "length": 458, "protein_name": "Interleukin-7 receptor subunit alpha", "gene_name": "IL7R", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "IL7R", "gene_names_refseq": "", "protein_names_uniprotkb": "Interleukin-7 receptor subunit alpha", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-1266695); (R-SSC-8856825); (R-SSC-8856828)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Receptor for interleukin-7. Also acts as a receptor for thymic stromal lymphopoietin (TSLP)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004896 cytokine receptor activity;GO:0004917 interleukin-7 receptor activity", "go_cellular_component": "GO:0016020 membrane;GO:0009897 external side of plasma membrane", "go_biological_process": "GO:0008284 positive regulation of cell population proliferation;GO:0019725 cellular homeostasis;GO:0050830 defense response to Gram-positive bacterium;GO:0030097 hemopoiesis;GO:0046427 positive regulation of receptor signaling pathway via JAK-STAT", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "K7GLC0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SJK6-1", "uniprot_id": "F1SJK6_PIG", "mass": 43183.0, "length": 362, "protein_name": "Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase", "gene_name": "HACD3", "organism": "Pig", "refseq_name": "very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3", "refseq_ac": "XP_003121777", "gene_names_uniprotkb": "HACD3", "gene_names_refseq": "HACD3", "protein_names_uniprotkb": "Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; 4.2.1.134", "protein_names_refseq": "very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3", "tax_id": 9823, "disease": "", "pathway": " (ssc:100154613); (R-SSC-75876)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0102158 very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase activity;GO:0019899 enzyme binding;GO:0018812 3-hydroxyacyl-CoA dehydratase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006633 fatty acid biosynthetic process;GO:0007264 small GTPase-mediated signal transduction;GO:0046726 positive regulation by virus of viral protein levels in host cell;GO:1902532 negative regulation of intracellular signal transduction;GO:0030148 sphingolipid biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SJK6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SQW0-1", "uniprot_id": "F1SQW0_PIG", "mass": 58072.0, "length": 524, "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "PAK2", "organism": "Pig", "refseq_name": "serine/threonine-protein kinase PAK 2", "refseq_ac": "XP_020925795", "gene_names_uniprotkb": "PAK2", "gene_names_refseq": "PAK2", "protein_names_uniprotkb": "non-specific serine/threonine protein kinase; 2.7.11.1", "protein_names_refseq": "serine/threonine-protein kinase PAK 2", "tax_id": 9823, "disease": "", "pathway": " (ssc:100511837); (R-SSC-202433); (R-SSC-2871796); (R-SSC-389359); (R-SSC-3928664); (R-SSC-399954); (R-SSC-4420097); (R-SSC-5218920); (R-SSC-5627123); (R-SSC-5687128); (R-SSC-9013148); (R-SSC-9013149); (R-SSC-9013404); (R-SSC-9013406); (R-SSC-9013407); (R-SSC-9013408); (R-SSC-9013420); (R-SSC-9013423); (R-SSC-9013424)", "pathway_count": 19, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A4X1TT72", "ec_number_list": "", "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0019901 protein kinase binding;GO:0042802 identical protein binding;GO:0031267 small GTPase binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0098978 glutamatergic synapse;GO:0005829 cytosol;GO:0005911 cell-cell junction;GO:0014069 postsynaptic density", "go_biological_process": "GO:0050770 regulation of axonogenesis;GO:0150105 protein localization to cell-cell junction;GO:0016477 cell migration;GO:0035556 intracellular signal transduction;GO:0043066 negative regulation of apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SQW0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SNL7-1", "uniprot_id": "F1SNL7_PIG", "mass": 52734.0, "length": 475, "protein_name": "Cytosolic non-specific dipeptidase", "gene_name": "CNDP2", "organism": "Pig", "refseq_name": "cytosolic non-specific dipeptidase", "refseq_ac": "NP_001230636", "gene_names_uniprotkb": "CNDP2", "gene_names_refseq": "CNDP2", "protein_names_uniprotkb": "Cytosolic non-specific dipeptidase; 3.4.13.18; CNDP dipeptidase 2; Threonyl dipeptidase", "protein_names_refseq": "CNDP dipeptidase 2 (metallopeptidase M20 family); cytosolic non-specific dipeptidase", "tax_id": 9823, "disease": "", "pathway": " (ssc:100158127); (R-SSC-174403); (R-SSC-9753281)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Catalyzes the peptide bond hydrolysis in dipeptides, displaying a non-redundant activity toward threonyl dipeptides. Mediates threonyl dipeptide catabolism in a tissue-specific way. Has high dipeptidase activity toward cysteinylglycine, an intermediate metabolite in glutathione metabolism. Metabolizes N-lactoyl-amino acids, both through hydrolysis to form lactic acid and amino acids, as well as through their formation by reverse proteolysis. Plays a role in the regulation of cell cycle arrest and apoptosis., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A4X1U2W5", "ec_number_list": "", "go_molecular_function": "GO:0008237 metallopeptidase activity;GO:0046872 metal ion binding;GO:0070573 metallodipeptidase activity;GO:0004180 carboxypeptidase activity;GO:0016805 dipeptidase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005654 nucleoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0006508 proteolysis;GO:0019184 nonribosomal peptide biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SNL7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SQX9-1", "uniprot_id": "F1SQX9_PIG", "mass": 21523.0, "length": 190, "protein_name": "Apolipoprotein D", "gene_name": "APOD", "organism": "Pig", "refseq_name": "apolipoprotein D", "refseq_ac": "XP_001926098", "gene_names_uniprotkb": "APOD", "gene_names_refseq": "APOD", "protein_names_uniprotkb": "Apolipoprotein D; Apo-D", "protein_names_refseq": "apolipoprotein D", "tax_id": 9823, "disease": "", "pathway": " (ssc:100157318); (R-SSC-804914)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A4X1U1N6;K7GN63", "ec_number_list": "", "go_molecular_function": "GO:0008289 lipid binding;GO:0015485 cholesterol binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0005615 extracellular space;GO:0048471 perinuclear region of cytoplasm;GO:0005737 cytoplasm;GO:0030425 dendrite", "go_biological_process": "GO:0006869 lipid transport;GO:0007420 brain development;GO:0006950 response to stress;GO:0042246 tissue regeneration;GO:0006629 lipid metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SQX9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SA41-1", "uniprot_id": "F1SA41_PIG", "mass": 77147.0, "length": 675, "protein_name": "Protein PALS1", "gene_name": "PALS1", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "PALS1", "gene_names_refseq": "", "protein_names_uniprotkb": "Protein PALS1; MAGUK p55 subfamily member 5; Protein associated with Lin-7 1", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (ssc:100152635)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A4X1UAE0", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0019904 protein domain specific binding;GO:0042802 identical protein binding", "go_cellular_component": "GO:0005912 adherens junction;GO:0005923 bicellular tight junction;GO:0016324 apical plasma membrane;GO:0005737 cytoplasm;GO:0005886 plasma membrane", "go_biological_process": "GO:0007420 brain development;GO:0008104 intracellular protein localization;GO:0048699 generation of neurons;GO:0017015 regulation of transforming growth factor beta receptor signaling pathway;GO:0016332 establishment or maintenance of polarity of embryonic epithelium", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SA41-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P81693-1", "uniprot_id": "PPAC_PIG", "mass": 18035.0, "length": 158, "protein_name": "Low molecular weight phosphotyrosine protein phosphatase", "gene_name": "ACP1", "organism": "Pig", "refseq_name": "low molecular weight phosphotyrosine protein phosphatase isoform 2", "refseq_ac": "XP_003481358", "gene_names_uniprotkb": "ACP1", "gene_names_refseq": "ACP1; LMW-PTPase; LMW-PTP", "protein_names_uniprotkb": "Low molecular weight phosphotyrosine protein phosphatase; 3.1.3.2; 3.1.3.48; LMW-PTPase; LMW-PTP; Low molecular weight cytosolic acid phosphatase", "protein_names_refseq": "Low molecular weight cytosolic acid phosphatase; acid phosphatase 1, soluble; low molecular weight phosphotyrosine protein phosphatase isoform 2; low molecular weight phosphotyrosine protein phosphatase", "tax_id": 9823, "disease": "", "pathway": " (ssc:100737301)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "32543654;8011064", "class_list": "", "function": "Acts on tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates with differences in substrate specificity between isoform 1 and isoform 2., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003993 acid phosphatase activity;GO:0004726 non-membrane spanning protein tyrosine phosphatase activity;GO:0004725 protein tyrosine phosphatase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0042383 sarcolemma;GO:0009898 cytoplasmic side of plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "P81693-1", "record_type": "protein" }, { "uniprot_canonical_ac": "I3LKR6-1", "uniprot_id": "I3LKR6_PIG", "mass": 25377.0, "length": 220, "protein_name": "T-cell-specific surface glycoprotein CD28", "gene_name": "CD28", "organism": "Pig", "refseq_name": "T-cell-specific surface glycoprotein CD28 precursor", "refseq_ac": "NP_001274339", "gene_names_uniprotkb": "CD28", "gene_names_refseq": "CD28; TP44", "protein_names_uniprotkb": "T-cell-specific surface glycoprotein CD28", "protein_names_refseq": "CD28 antigen; T-cell-specific surface glycoprotein CD28 precursor", "tax_id": 9823, "disease": "", "pathway": " (ssc:100515419); (R-SSC-1257604); (R-SSC-389356); (R-SSC-389357); (R-SSC-389359); (R-SSC-6811558)", "pathway_count": 6, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Receptor that plays a role in T-cell activation, proliferation, survival and the maintenance of immune homeostasis. Functions not only as an amplifier of TCR signals but delivers unique signals that control intracellular biochemical events that alter the gene expression program of T-cells. Stimulation upon engagement of its cognate ligands CD80 or CD86 increases proliferation and expression of various cytokines in particular IL2 production in both CD4(+) and CD8(+) T-cell subsets. Mechanistically, ligation induces recruitment of protein kinase C-theta/PRKCQ and GRB2 leading to NF-kappa-B activation via both PI3K/Akt-dependent and -independent pathways. In conjunction with TCR/CD3 ligation and CD40L costimulation, enhances the production of IL4 and IL10 in T-cells., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A4X1V5B4;I1X3U8", "ec_number_list": "", "go_molecular_function": "GO:0004888 transmembrane signaling receptor activity;GO:0019901 protein kinase binding", "go_cellular_component": "GO:0016020 membrane;GO:0009897 external side of plasma membrane;GO:0001772 immunological synapse;GO:0098636 protein complex involved in cell adhesion", "go_biological_process": "GO:0006955 immune response;GO:0042129 regulation of T cell proliferation;GO:0010629 negative regulation of gene expression;GO:0031295 T cell costimulation;GO:0042110 T cell activation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "I3LKR6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P67872-1", "uniprot_id": "CSK2B_PIG", "mass": 24942.0, "length": 215, "protein_name": "Casein kinase II subunit beta", "gene_name": "CSNK2B", "organism": "Pig", "refseq_name": "casein kinase II subunit beta", "refseq_ac": "NP_001138849", "gene_names_uniprotkb": "CSNK2B; CK2N", "gene_names_refseq": "CK2N; CKII beta; CSNK2B", "protein_names_uniprotkb": "Casein kinase II subunit beta; CK II beta; Phosvitin", "protein_names_refseq": "casein kinase II beta subunit; casein kinase II subunit beta; phosvitin", "tax_id": 9823, "disease": "", "pathway": " (ssc:397211); (R-SSC-1483191); (R-SSC-201688); (R-SSC-2514853); (R-SSC-6798695); (R-SSC-6804756); (R-SSC-6814122); (R-SSC-8934903); (R-SSC-8939243); (R-SSC-8948751); (R-SSC-9768727); (R-SSC-9929491)", "pathway_count": 12, "publication_count": 2, "publication_id_list": "2015307;32543654", "class_list": "", "function": "Regulatory subunit of casein kinase II/CK2. As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine (By similarity). Participates in Wnt signaling., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "P07312;P13862", "ec_number_list": "", "go_molecular_function": "GO:0046872 metal ion binding;GO:0019887 protein kinase regulator activity;GO:0003682 chromatin binding;GO:0004674 protein serine/threonine kinase activity;GO:0005102 signaling receptor binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005956 protein kinase CK2 complex;GO:0005886 plasma membrane;GO:0001650 fibrillar center", "go_biological_process": "GO:0016055 Wnt signaling pathway;GO:0043537 negative regulation of blood vessel endothelial cell migration;GO:0033211 adiponectin-activated signaling pathway;GO:0032927 positive regulation of activin receptor signaling pathway;GO:0061154 endothelial tube morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "P67872-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SKQ1-1", "uniprot_id": "F1SKQ1_PIG", "mass": 37699.0, "length": 340, "protein_name": "Meiotic recombination protein", "gene_name": "DMC1", "organism": "Pig", "refseq_name": "meiotic recombination protein DMC1/LIM15 homolog isoform X1", "refseq_ac": "XP_005655549", "gene_names_uniprotkb": "DMC1", "gene_names_refseq": "DMC1", "protein_names_uniprotkb": "Meiotic recombination protein", "protein_names_refseq": "meiotic recombination protein DMC1/LIM15 homolog isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100522866); (R-SSC-912446)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Participates in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A4X1VKP8", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0005524 ATP binding;GO:0140664 ATP-dependent DNA damage sensor activity;GO:0000150 DNA strand exchange activity;GO:0042802 identical protein binding", "go_cellular_component": "GO:0005634 nucleus;GO:0000794 condensed nuclear chromosome;GO:0035861 site of double-strand break;GO:0000800 lateral element;GO:0000781 chromosome, telomeric region", "go_biological_process": "GO:0006281 DNA repair;GO:0051321 meiotic cell cycle;GO:0007283 spermatogenesis;GO:0007131 reciprocal meiotic recombination;GO:0007292 female gamete generation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SKQ1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "I3LN58-1", "uniprot_id": "I3LN58_PIG", "mass": 76301.0, "length": 659, "protein_name": "Tyrosine-protein kinase", "gene_name": "BTK", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "BTK", "gene_names_refseq": "", "protein_names_uniprotkb": "Tyrosine-protein kinase; 2.7.10.2", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-2424491); (R-SSC-2871809); (R-SSC-416476); (R-SSC-416482); (R-SSC-983695)", "pathway_count": 5, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "A0A4X1W3S0", "ec_number_list": "", "go_molecular_function": "GO:0004715 non-membrane spanning protein tyrosine kinase activity;GO:0005524 ATP binding;GO:0008270 zinc ion binding;GO:0008289 lipid binding;GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding", "go_cellular_component": "GO:0005829 cytosol;GO:0005634 nucleus;GO:0005886 plasma membrane;GO:0045121 membrane raft;GO:0031410 cytoplasmic vesicle", "go_biological_process": "GO:0035556 intracellular signal transduction;GO:0006351 DNA-templated transcription;GO:0045087 innate immune response;GO:0042113 B cell activation;GO:0002250 adaptive immune response", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "I3LN58-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1S3J9-1", "uniprot_id": "F1S3J9_PIG", "mass": 58434.0, "length": 537, "protein_name": "Intercellular adhesion molecule 1", "gene_name": "ICAM1", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "ICAM1", "gene_names_refseq": "", "protein_names_uniprotkb": "Intercellular adhesion molecule 1", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-198933); (R-SSC-216083)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Cell adhesion molecule that functions as a receptor ligand of the signaling receptor ITGAL:ITGB2/LFA-1 (lymphocyte-function associated (LFA) molecule 1) ensuring leukocyte cell-cell adhesion, by providing a calibrated system to namely adjust T-cell killing to the antigen stimulation strength. Also functions as a ligand receptor of the signaling receptor ITGAM:ITGB2/MAC-1 ensuring adhesion between stimulated neutrophils and stimulated endothelial cells. During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. Promotes cell aggregation in epithelial cells through interaction with MUC1., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005178 integrin binding;GO:0048018 receptor ligand activity", "go_cellular_component": "GO:0016020 membrane;GO:0005886 plasma membrane;GO:0045121 membrane raft;GO:0070062 extracellular exosome;GO:0009897 external side of plasma membrane", "go_biological_process": "GO:0006955 immune response;GO:0007159 leukocyte cell-cell adhesion;GO:0050900 leukocyte migration;GO:1901701 cellular response to oxygen-containing compound;GO:0002252 immune effector process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1S3J9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "I3LG77-1", "uniprot_id": "I3LG77_PIG", "mass": 71968.0, "length": 627, "protein_name": "Deoxynucleoside triphosphate triphosphohydrolase SAMHD1", "gene_name": "SAMHD1", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "SAMHD1", "gene_names_refseq": "", "protein_names_uniprotkb": "Deoxynucleoside triphosphate triphosphohydrolase SAMHD1", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-8956319)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "31152619;32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005525 GTP binding;GO:0008832 dGTPase activity;GO:0003824 catalytic activity;GO:0046872 metal ion binding;GO:0003723 RNA binding", "go_cellular_component": "GO:0005694 chromosome;GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0097197 tetraspanin-enriched microdomain;GO:0035861 site of double-strand break", "go_biological_process": "GO:0006281 DNA repair;GO:0051289 protein homotetramerization;GO:0051607 defense response to virus;GO:0006260 DNA replication;GO:0046061 dATP catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "I3LG77-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SNV7-1", "uniprot_id": "F1SNV7_PIG", "mass": 83308.0, "length": 753, "protein_name": "Lysyl oxidase homolog", "gene_name": "LOXL3", "organism": "Pig", "refseq_name": "lysyl oxidase homolog 3 isoform X1", "refseq_ac": "XP_020942983", "gene_names_uniprotkb": "LOXL3", "gene_names_refseq": "LOXL3", "protein_names_uniprotkb": "Lysyl oxidase homolog; 1.4.3.13", "protein_names_refseq": "lysyl oxidase homolog 3 isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100512652); (R-SSC-1566948); (R-SSC-2243919)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005507 copper ion binding;GO:0004720 protein-lysine 6-oxidase activity;GO:0001968 fibronectin binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0016020 membrane;GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0031012 extracellular matrix", "go_biological_process": "GO:0006954 inflammatory response;GO:0021510 spinal cord development;GO:0030324 lung development;GO:0045892 negative regulation of DNA-templated transcription;GO:0030199 collagen fibril organization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SNV7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1RVK2-1", "uniprot_id": "F1RVK2_PIG", "mass": 96984.0, "length": 875, "protein_name": "Serine/threonine-protein kinase greatwall", "gene_name": "MASTL", "organism": "Pig", "refseq_name": "serine/threonine-protein kinase greatwall isoform X4", "refseq_ac": "XP_005668187", "gene_names_uniprotkb": "MASTL", "gene_names_refseq": "MASTL", "protein_names_uniprotkb": "Serine/threonine-protein kinase greatwall; 2.7.11.1; Microtubule-associated serine/threonine-protein kinase-like", "protein_names_refseq": "serine/threonine-protein kinase greatwall isoform X4", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-2465910)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Serine/threonine kinase that plays a key role in M phase by acting as a regulator of mitosis entry and maintenance. Acts by promoting the inactivation of protein phosphatase 2A (PP2A) during M phase: does not directly inhibit PP2A but acts by mediating phosphorylation and subsequent activation of ARPP19 and ENSA at 'Ser-62' and 'Ser-67', respectively. ARPP19 and ENSA are phosphatase inhibitors that specifically inhibit the PPP2R2D (PR55-delta) subunit of PP2A. Inactivation of PP2A during M phase is essential to keep cyclin-B1-CDK1 activity high. Following DNA damage, it is also involved in checkpoint recovery by being inhibited., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0016301 kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005813 centrosome;GO:0015630 microtubule cytoskeleton;GO:0032154 cleavage furrow", "go_biological_process": "GO:0007147 female meiosis II;GO:0035556 intracellular signal transduction;GO:0051301 cell division;GO:0000086 G2/M transition of mitotic cell cycle;GO:0007346 regulation of mitotic cell cycle", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1RVK2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "K7GSR7-1", "uniprot_id": "K7GSR7_PIG", "mass": 51612.0, "length": 457, "protein_name": "5-hydroxytryptamine receptor 2C", "gene_name": "HTR2C", "organism": "Pig", "refseq_name": "5-hydroxytryptamine receptor 2C", "refseq_ac": "NP_001421869", "gene_names_uniprotkb": "HTR2C", "gene_names_refseq": "5HTR2C; HTR2C", "protein_names_uniprotkb": "5-hydroxytryptamine receptor 2C; Serotonin receptor 2C", "protein_names_refseq": "5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled; 5-hydroxytryptamine receptor 2C", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-390666); (R-SSC-416476)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "22471812;32543654", "class_list": "", "function": "Although the expression of the long transcriptional variant of HTR2C is raised in infanticidal animals, the overall patterns of editing in the hypothalamus are similar between the two states. 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Retinol-binding protein receptor STRA6", "protein_names_refseq": "stimulated by retinoic acid gene 6 protein homolog", "tax_id": 9823, "disease": "", "pathway": " (ssc:100153335); (R-SSC-2453902)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0019841 retinol binding;GO:0016918 retinal binding;GO:0034632 retinol transmembrane transporter activity;GO:0038023 signaling receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0032991 protein-containing complex", "go_biological_process": "GO:0030540 female genitalia development;GO:0043585 nose morphogenesis;GO:0048520 positive regulation of behavior;GO:0060900 embryonic camera-type eye formation;GO:0061143 alveolar primary septum development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SIE2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "I3LP81-1", "uniprot_id": "I3LP81_PIG", "mass": 48043.0, "length": 461, "protein_name": "TNF receptor superfamily member 1B", "gene_name": "TNFRSF1B", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "TNFRSF1B", "gene_names_refseq": "", "protein_names_uniprotkb": "TNF receptor superfamily member 1B", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-5668541); (R-SSC-5669034); (R-SSC-6798695)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005031 tumor necrosis factor receptor activity;GO:0043120 tumor necrosis factor binding;GO:0031625 ubiquitin protein ligase binding", "go_cellular_component": "GO:0016020 membrane;GO:0045121 membrane raft", "go_biological_process": "GO:0006954 inflammatory response;GO:0048714 positive regulation of oligodendrocyte differentiation;GO:0051044 positive regulation of membrane protein ectodomain proteolysis;GO:0071222 cellular response to lipopolysaccharide;GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "I3LP81-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1RTW1-1", "uniprot_id": "F1RTW1_PIG", "mass": 112066.0, "length": 1037, "protein_name": "RE1-silencing transcription factor", "gene_name": "", "organism": "Pig", "refseq_name": "RE1 silencing transcription factor", "refseq_ac": "XP_003129069", "gene_names_uniprotkb": "", "gene_names_refseq": "REST", "protein_names_uniprotkb": "RE1-silencing transcription factor; Neural-restrictive silencer factor", "protein_names_refseq": "RE1 silencing transcription factor", "tax_id": 9823, "disease": "", "pathway": " (ssc:100520754); (ssc:100621006); (R-SSC-3214815)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "A0A287BB02", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0043565 sequence-specific DNA binding;GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding;GO:0003682 chromatin binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0017053 transcription repressor complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045665 negative regulation of neuron differentiation;GO:0006950 response to stress;GO:0060379 cardiac muscle cell myoblast differentiation;GO:0045892 negative regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1RTW1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "K7GPS0-1", "uniprot_id": "K7GPS0_PIG", "mass": 44491.0, "length": 400, "protein_name": "Dual specificity mitogen-activated protein kinase kinase 2", "gene_name": "MAP2K2", "organism": "Pig", "refseq_name": "dual specificity mitogen-activated protein kinase kinase 2", "refseq_ac": "NP_001231479", "gene_names_uniprotkb": "MAP2K2", "gene_names_refseq": "MAP2K2", "protein_names_uniprotkb": "Dual specificity mitogen-activated protein kinase kinase 2; 2.7.12.2; ERK activator kinase 2; MAPK/ERK kinase 2", "protein_names_refseq": "dual specificity mitogen-activated protein kinase kinase 2", "tax_id": 9823, "disease": "", "pathway": " (ssc:100525505); (R-SSC-112411); (R-SSC-170968); (R-SSC-445144); (R-SSC-5673000); (R-SSC-5674135)", "pathway_count": 6, "publication_count": 2, "publication_id_list": "19570883;32543654", "class_list": "", "function": "20-HETE activates the Raf/MEK/ERK pathway in renal epithelial cells through an EGFR- and c-Src-dependent mechanism., [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0004713 protein tyrosine kinase activity;GO:0005524 ATP binding;GO:0004708 MAP kinase kinase activity;GO:0030165 PDZ domain binding", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005769 early endosome;GO:0005829 cytosol;GO:0005925 focal adhesion;GO:0005770 late endosome", "go_biological_process": "GO:2000641 regulation of early endosome to late endosome transport;GO:0032872 regulation of stress-activated MAPK cascade;GO:0090170 regulation of Golgi inheritance;GO:0010628 positive regulation of gene expression;GO:0000165 MAPK cascade", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "K7GPS0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "I3LPE8-1", "uniprot_id": "I3LPE8_PIG", "mass": 69662.0, "length": 640, "protein_name": "Tumor protein p73", "gene_name": "TP73", "organism": "Pig", "refseq_name": "tumor protein p73 isoform X2", "refseq_ac": "XP_020950875", "gene_names_uniprotkb": "TP73", "gene_names_refseq": "TP73", "protein_names_uniprotkb": "Tumor protein p73", "protein_names_refseq": "tumor protein p73 isoform X2", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-6804759); (R-SSC-8939236)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Multifunctional transcription factor that induces cell cycle arrest, DNA repair or apoptosis upon binding to its target DNA sequence. Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Negatively regulates cell division by controlling expression of a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0046872 metal ion binding;GO:0000976 transcription cis-regulatory region binding;GO:0019901 protein kinase binding;GO:0042802 identical protein binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005783 endoplasmic reticulum;GO:0005813 centrosome;GO:0005654 nucleoplasm;GO:0000785 chromatin", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0051262 protein tetramerization;GO:0006915 apoptotic process;GO:1901248 positive regulation of lung ciliated cell differentiation;GO:0045944 positive regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "I3LPE8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P49068-1", "uniprot_id": "MT1A_PIG", "mass": 5969.0, "length": 61, "protein_name": "Metallothionein-1A", "gene_name": "MT1A", "organism": "Pig", "refseq_name": "metallothionein-1A", "refseq_ac": "NP_001001266", "gene_names_uniprotkb": "MT1A; MT1", "gene_names_refseq": "MT-IA; MT1A; MT1", "protein_names_uniprotkb": "Metallothionein-1A; MT-1A; MT-IA; Metallothionein-IA", "protein_names_refseq": "metallothionein-1A; metallothionein-IA", "tax_id": 9823, "disease": "", "pathway": " (ssc:397417); (R-SSC-5661231)", "pathway_count": 2, "publication_count": 7, "publication_id_list": "14988443;15812196;22760644;2474864;27049121;32543654;9573337", "class_list": "", "function": "1000 mg Zn/kg with phytase enhances MT mRNA abundance and protein and Zn absorption., [RefSeq, PubMed]; Data using an isolated, soluble recombinant His-tagged MT1A suggest high-affinity metal-binding activity with divalent metal ions copper, zinc, and cadmium., [RefSeq, PubMed]; Expression of MT-1a, MT-2b and MT-3 were significantly higher in high zinc fed pigs., [RefSeq, PubMed]; Metallothioneins have a high content of cysteine residues that bind various heavy metals., [UniProtKB, UniProtKB]; Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids., [UniProtKB]; Zn caused a dose-dependent increase of metallothionein on the RNA as well as on the protein level in kidney epithelial tubular cells, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "P79375", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0071276 cellular response to cadmium ion;GO:0071280 cellular response to copper ion;GO:0010273 detoxification of copper ion;GO:0006882 intracellular zinc ion homeostasis;GO:0071294 cellular response to zinc ion", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P49068-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P04119-1", "uniprot_id": "LACB_PIG", "mass": 19734.0, "length": 178, "protein_name": "Beta-lactoglobulin-1A/1C", "gene_name": "PAEP", "organism": "Pig", "refseq_name": "beta-lactoglobulin-1A/1C precursor", "refseq_ac": "NP_998919", "gene_names_uniprotkb": "PAEP", "gene_names_refseq": "BLG; PAEP", "protein_names_uniprotkb": "Beta-lactoglobulin-1A/1C; Beta-LG; Beta-lactoglobulin IA/IC", "protein_names_refseq": "beta-LG; beta-lactoglobulin IA/IC; beta-lactoglobulin-1A/1C precursor; beta-lactoglobulin-1A/1C", "tax_id": 9823, "disease": "", "pathway": " (ssc:396596)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "11856834;1503260;2009291;32543654;3790256;7231399", "class_list": "", "function": "Lactoglobulin is the primary component of whey, it binds retinol and is probably involved in the transport of that molecule., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q53Z18", "ec_number_list": "", "go_molecular_function": "GO:0019841 retinol binding", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P04119-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P61958-1", "uniprot_id": "SUMO2_PIG", "mass": 10871.0, "length": 95, "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "organism": "Pig", "refseq_name": "small ubiquitin-related modifier 2", "refseq_ac": "NP_999149", "gene_names_uniprotkb": "SUMO2; SMT3A; SMT3H2", "gene_names_refseq": "PSMT3; SMT3H2; SUMO2; Smt3A", "protein_names_uniprotkb": "Small ubiquitin-related modifier 2; MIF2 suppressor; SMT3 homolog 2; SUMO-2; Sentrin-2; Smt3A; Ubiquitin-like protein SMT3A", "protein_names_refseq": "MIF2 suppressor; SMT3 homolog 2; SMT3 suppressor of mif two 3 homolog 2; SUMO-2; sentrin-2; small ubiquitin-related modifier 2; ubiquitin-like protein SMT3A; ubiquitin-like protein SMT3B", "tax_id": 9823, "disease": "", "pathway": " (ssc:397044); (R-SSC-3065679); (R-SSC-3108214); (R-SSC-3232118); (R-SSC-3899300); (R-SSC-4090294); (R-SSC-4551638); (R-SSC-4615885); (R-SSC-4755510); (R-SSC-5696395)", "pathway_count": 10, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Ubiquitin-like protein that can be covalently attached to proteins as a monomer or as a lysine-linked polymer. Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by an E3 ligase such as PIAS1-4, RANBP2 or CBX4. This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Polymeric SUMO2 chains are also susceptible to polyubiquitination which functions as a signal for proteasomal degradation of modified proteins. Plays a role in the regulation of sumoylation status of SETX (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A7WLH9;P55855", "ec_number_list": "", "go_molecular_function": "GO:0031625 ubiquitin protein ligase binding;GO:0019789 SUMO transferase activity;GO:0044389 ubiquitin-like protein ligase binding;GO:0031386 protein tag activity", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0098982 GABA-ergic synapse;GO:0005634 nucleus;GO:0016605 PML body;GO:0098686 hippocampal mossy fiber to CA3 synapse", "go_biological_process": "GO:0016925 protein sumoylation;GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "P61958-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SRG4-1", "uniprot_id": "F1SRG4_PIG", "mass": 56628.0, "length": 500, "protein_name": "Cytochrome P450", "gene_name": "CYP2D6", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "CYP2D6", "gene_names_refseq": "", "protein_names_uniprotkb": "Cytochrome P450; 1.14.14.-", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-211935); (R-SSC-211958); (R-SSC-211981); (R-SSC-211999); (R-SSC-9027307); (R-SSC-9749641)", "pathway_count": 6, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A0H4ITY7;F1SRG3", "ec_number_list": "", "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0004497 monooxygenase activity;GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen", "go_cellular_component": "GO:0016020 membrane;GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0008210 estrogen metabolic process;GO:0016098 monoterpenoid metabolic process;GO:0042572 retinol metabolic process;GO:0006805 xenobiotic metabolic process;GO:0042178 xenobiotic catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SRG4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1RZK8-1", "uniprot_id": "F1RZK8_PIG", "mass": 55304.0, "length": 488, "protein_name": "Histone deacetylase 2", "gene_name": "HDAC2", "organism": "Pig", "refseq_name": "histone deacetylase 2", "refseq_ac": "XP_001925353", "gene_names_uniprotkb": "HDAC2", "gene_names_refseq": "HDAC2", "protein_names_uniprotkb": "Histone deacetylase 2; 3.5.1.98; HD2", "protein_names_refseq": "histone deacetylase 2", "tax_id": 9823, "disease": "", "pathway": " (ssc:100156170); (R-SSC-3214815); (R-SSC-350054); (R-SSC-4551638); (R-SSC-6804758); (R-SSC-73762); (R-SSC-8943724); (R-SSC-9022692); (R-SSC-9701898); (R-SSC-9764725); (R-SSC-983231); (R-SSC-9937850); (R-SSC-9940951)", "pathway_count": 13, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Histone deacetylase that catalyzes the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0046872 metal ion binding;GO:0140297 DNA-binding transcription factor binding;GO:0160008 protein decrotonylase activity;GO:0160216 protein lysine delactylase activity;GO:0141221 histone deacetylase activity, hydrolytic mechanism", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0000785 chromatin;GO:0032991 protein-containing complex;GO:0035098 ESC/E(Z) complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0008284 positive regulation of cell population proliferation;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0010944 negative regulation of transcription by competitive promoter binding", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1RZK8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "I3LGX5-1", "uniprot_id": "I3LGX5_PIG", "mass": 63975.0, "length": 562, "protein_name": "Ceramide transfer protein", "gene_name": "CERT1", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "CERT1", "gene_names_refseq": "", "protein_names_uniprotkb": "Ceramide transfer protein; Collagen type IV alpha-3-binding protein", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Plays a role in endocytic trafficking. Required for receptor recycling from endosomes, both to the trans-Golgi network and the plasma membrane., [UniProtKB, UniProtKB]; Shelters ceramides inside its steroidogenic acute regulatory lipid transfer (START) domain and mediates their intracellular trafficking in a non-vesicular manner from the endoplasmic reticulum to the Golgi apparatus for conversion to sphingomyelin. Efficiently transfers ceramide molecules having long-chain fatty chains, but not those with very long acyl chains. Capable of transferring diacylglycerol, although with very low efficiency., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0016301 kinase activity;GO:0097001 ceramide binding;GO:0120017 ceramide transfer activity", "go_cellular_component": "GO:0005769 early endosome;GO:0005829 cytosol;GO:0055037 recycling endosome;GO:0030136 clathrin-coated vesicle;GO:0005802 trans-Golgi network", "go_biological_process": "GO:0007032 endosome organization;GO:0001881 receptor recycling;GO:0042147 retrograde transport, endosome to Golgi;GO:0006686 sphingomyelin biosynthetic process;GO:0006672 ceramide metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "I3LGX5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SC07-1", "uniprot_id": "DYH11_PIG", "mass": 519618.0, "length": 4518, "protein_name": "Dynein axonemal heavy chain 11", "gene_name": "DNAH11", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "DNAH11", "gene_names_refseq": "", "protein_names_uniprotkb": "Dynein axonemal heavy chain 11; Axonemal beta dynein heavy chain 11; Ciliary dynein heavy chain 11", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 2, "publication_id_list": "32543654;33139725", "class_list": "", "function": "Force generating protein required for cilia beating in respiratory epithelia (By similarity). Produces force towards the minus ends of microtubules (By similarity). Key component of dynein, a family of motor proteins essential for movement along microtubules (By similarity). Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP (By similarity). Required for structural and functional integrity of cilia (By similarity)., [UniProtKB, UniProtKB, UniProtKB]; Force generating protein required for cilia beating in respiratory epithelia. Produces force towards the minus ends of microtubules. Key component of dynein, a family of motor proteins essential for movement along microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Required for structural and functional integrity of cilia., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0008569 minus-end-directed microtubule motor activity;GO:0051959 dynein light intermediate chain binding;GO:0045505 dynein intermediate chain binding", "go_cellular_component": "GO:0005874 microtubule;GO:0005930 axoneme;GO:0030286 dynein complex;GO:0097729 9+2 motile cilium;GO:0097728 9+0 motile cilium", "go_biological_process": "GO:0060294 cilium movement involved in cell motility;GO:0007018 microtubule-based movement;GO:0120229 protein localization to motile cilium", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "F1SC07-1", "record_type": "protein" }, { "uniprot_canonical_ac": "K7GMV8-1", "uniprot_id": "K7GMV8_PIG", "mass": 99787.0, "length": 874, "protein_name": "Ectonucleotide pyrophosphatase/phosphodiesterase family member 3", "gene_name": "ENPP3", "organism": "Pig", "refseq_name": "ectonucleotide pyrophosphatase/phosphodiesterase family member 3 isoform X1", "refseq_ac": "XP_020943612", "gene_names_uniprotkb": "ENPP3", "gene_names_refseq": "ENPP3", "protein_names_uniprotkb": "Ectonucleotide pyrophosphatase/phosphodiesterase family member 3; 3.1.4.1; 3.6.1.9; Alkaline phosphodiesterase I; Dinucleoside polyphosphatase; Nucleotide diphosphatase; Nucleotide pyrophosphatase; Phosphodiesterase I beta; Phosphodiesterase I/nucleotide pyrophosphatase 3", "protein_names_refseq": "ectonucleotide pyrophosphatase/phosphodiesterase family member 3 isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100621671)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0046872 metal ion binding;GO:0004528 phosphodiesterase I activity;GO:0047429 nucleoside triphosphate diphosphatase activity;GO:0034432 bis(5'-adenosyl)-pentaphosphatase activity;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0005886 plasma membrane;GO:0048471 perinuclear region of cytoplasm;GO:0009897 external side of plasma membrane;GO:0016324 apical plasma membrane", "go_biological_process": "GO:0050728 negative regulation of inflammatory response;GO:0055062 phosphate ion homeostasis;GO:0046034 ATP metabolic process;GO:0009143 nucleoside triphosphate catabolic process;GO:0070667 negative regulation of mast cell proliferation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "K7GMV8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F2Z5H1-1", "uniprot_id": "F2Z5H1_PIG", "mass": 64855.0, "length": 576, "protein_name": "Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN", "gene_name": "PTEN", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "PTEN", "gene_names_refseq": "", "protein_names_uniprotkb": "Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; 3.1.3.16; 3.1.3.48; 3.1.3.67; Inositol polyphosphate 3-phosphatase; Phosphatase and tensin homolog", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-1660499); (R-SSC-1855204); (R-SSC-199418); (R-SSC-202424); (R-SSC-5689880); (R-SSC-5689896); (R-SSC-8948747); (R-SSC-8948751)", "pathway_count": 8, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity;GO:0004722 protein serine/threonine phosphatase activity;GO:0004725 protein tyrosine phosphatase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0043005 neuron projection;GO:0005634 nucleus;GO:0005829 cytosol;GO:0005886 plasma membrane", "go_biological_process": "GO:0050793 regulation of developmental process;GO:0006629 lipid metabolic process;GO:0051896 regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction;GO:0043491 phosphatidylinositol 3-kinase/protein kinase B signal transduction;GO:0048870 cell motility", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F2Z5H1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SR53-1", "uniprot_id": "F1SR53_PIG", "mass": 115442.0, "length": 1057, "protein_name": "Integrin alpha-5", "gene_name": "ITGA5", "organism": "Pig", "refseq_name": "integrin alpha-5", "refseq_ac": "XP_001925287", "gene_names_uniprotkb": "ITGA5", "gene_names_refseq": "ITGA5", "protein_names_uniprotkb": "Integrin alpha-5; Fibronectin receptor subunit alpha; Integrin alpha-F; VLA-5", "protein_names_refseq": "integrin alpha-5", "tax_id": 9823, "disease": "", "pathway": " (ssc:100155091); (R-SSC-1566977); (R-SSC-202733); (R-SSC-216083); (R-SSC-9634597); (R-SSC-9860927)", "pathway_count": 6, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Integrin alpha-5/beta-1 (ITGA5:ITGB1) is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands. ITGA5:ITGB1 binds to PLA2G2A via a site (site 2) which is distinct from the classical ligand-binding site (site 1) and this induces integrin conformational changes and enhanced ligand binding to site 1. ITGA5:ITGB1 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1. ITGA5:ITGB1 acts as a receptor for fibronectin (FN1) and mediates R-G-D-dependent cell adhesion to FN1. ITGA5:ITGB1 is a receptor for IL1B and binding is essential for IL1B signaling. ITGA5:ITGB3 is a receptor for soluble CD40LG and is required for CD40/CD40LG signaling., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005102 signaling receptor binding;GO:0046872 metal ion binding;GO:0005178 integrin binding;GO:0005509 calcium ion binding;GO:0038023 signaling receptor activity", "go_cellular_component": "GO:0005925 focal adhesion;GO:0009986 cell surface;GO:0008305 integrin complex;GO:0030054 cell junction;GO:0005783 endoplasmic reticulum", "go_biological_process": "GO:0007229 integrin-mediated signaling pathway;GO:0033627 cell adhesion mediated by integrin;GO:0098609 cell-cell adhesion;GO:0045765 regulation of angiogenesis;GO:0007155 cell adhesion", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SR53-1", "record_type": "protein" }, { "uniprot_canonical_ac": "I3L942-1", "uniprot_id": "I3L942_PIG", "mass": 150993.0, "length": 1351, "protein_name": "Regulatory-associated protein of mTOR", "gene_name": "RPTOR", "organism": "Pig", "refseq_name": "regulatory-associated protein of mTOR isoform X1", "refseq_ac": "XP_020922151", "gene_names_uniprotkb": "RPTOR", "gene_names_refseq": "RPTOR", "protein_names_uniprotkb": "Regulatory-associated protein of mTOR; p150 target of rapamycin (TOR)-scaffold protein", "protein_names_refseq": "regulatory-associated protein of mTOR isoform X1", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-1632852); (R-SSC-165159); (R-SSC-166208); (R-SSC-3371571); (R-SSC-380972); (R-SSC-5628897); (R-SSC-8943724); (R-SSC-9639288)", "pathway_count": 8, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0019901 protein kinase binding;GO:0030674 protein-macromolecule adaptor activity;GO:0030295 protein kinase activator activity;GO:0044877 protein-containing complex binding", "go_cellular_component": "GO:0005764 lysosome;GO:0031931 TORC1 complex;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005765 lysosomal membrane", "go_biological_process": "GO:0038202 TORC1 signaling;GO:0023051 regulation of signaling;GO:0010646 regulation of cell communication;GO:0080090 regulation of primary metabolic process;GO:0060255 regulation of macromolecule metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "I3L942-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SV76-1", "uniprot_id": "F1SV76_PIG", "mass": 99068.0, "length": 934, "protein_name": "Progesterone receptor", "gene_name": "PGR", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "PGR", "gene_names_refseq": "", "protein_names_uniprotkb": "Progesterone receptor; Nuclear receptor subfamily 3 group C member 3; PR", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-3371497); (R-SSC-383280); (R-SSC-4090294); (R-SSC-9018519)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Steroid hormone receptor involved in the regulation of eukaryotic gene expression which affects cellular proliferation and differentiation in target tissues., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0003707 nuclear steroid receptor activity;GO:0005496 steroid binding;GO:0043565 sequence-specific DNA binding;GO:0034056 estrogen response element binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0000785 chromatin", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0010629 negative regulation of gene expression;GO:0051457 maintenance of protein location in nucleus;GO:0030518 nuclear receptor-mediated steroid hormone signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SV76-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P15540-1", "uniprot_id": "CP21A_PIG", "mass": 55620.0, "length": 492, "protein_name": "Steroid 21-hydroxylase", "gene_name": "CYP21A1; CYP21", "organism": "Pig", "refseq_name": "steroid 21-hydroxylase", "refseq_ac": "NP_999598", "gene_names_uniprotkb": "CYP21A1; CYP21; CYP21A1; CYP21A2; CYP21A3", "gene_names_refseq": "CYP21A1; CYP21A2; CYP21", "protein_names_uniprotkb": "Steroid 21-hydroxylase; 1.14.14.16; 21-OHase; Cytochrome P-450c21; Cytochrome P450 21; Cytochrome P450 XXI; Cytochrome P450-C21", "protein_names_refseq": "21-OHase; FK506 binding protein like; cytochrome P-450c21; cytochrome P450 21-hydroxylase; cytochrome P450 XXI; cytochrome P450, family 21, subfamily A, polypepide 2; cytochrome P450-C21; steroid 21-hydroxylase", "tax_id": 9823, "disease": "", "pathway": " (ssc:403337); (R-SSC-193993); (R-SSC-194002); (R-SSC-211976)", "pathway_count": 4, "publication_count": 7, "publication_id_list": "12643481;1482677;16965408;2109953;28677294;32543654;3495238", "class_list": "", "function": "A cytochrome P450 monooxygenase that plays a major role in adrenal steroidogenesis. Catalyzes the hydroxylation at C-21 of progesterone and 17alpha-hydroxyprogesterone to respectively form 11-deoxycorticosterone and 11-deoxycortisol, intermediate metabolites in the biosynthetic pathway of mineralocorticoids and glucocorticoids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase)., [UniProtKB, UniProtKB, UniProtKB]; CYP21 gene polymorphisms were analyzed in association with litter size., [RefSeq, PubMed]; It plays a role on cortisol production and depends on stress. And expression of CYP21 protein will provide the basis for information and better understanding of the mechanisms related to drip loss in pork., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A5A8W6;Q02390", "ec_number_list": "", "go_molecular_function": "GO:0005506 iron ion binding;GO:0005496 steroid binding;GO:0020037 heme binding;GO:0004509 steroid 21-monooxygenase activity;GO:0008395 steroid hydroxylase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006704 glucocorticoid biosynthetic process;GO:0008202 steroid metabolic process;GO:0034651 cortisol biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P15540-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SHT5-1", "uniprot_id": "F1SHT5_PIG", "mass": 30027.0, "length": 272, "protein_name": "Homeobox protein", "gene_name": "HOXA9", "organism": "Pig", "refseq_name": "homeobox protein Hox-A9", "refseq_ac": "XP_003134886", "gene_names_uniprotkb": "HOXA9", "gene_names_refseq": "HOXA9", "protein_names_uniprotkb": "Homeobox protein", "protein_names_refseq": "homeobox protein Hox-A9", "tax_id": 9823, "disease": "", "pathway": " (ssc:100519066)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0003700 DNA-binding transcription factor activity;GO:0019899 enzyme binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005667 transcription regulator complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0009952 anterior/posterior pattern specification;GO:0009954 proximal/distal pattern formation;GO:0042118 endothelial cell activation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SHT5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "I3LBZ2-1", "uniprot_id": "I3LBZ2_PIG", "mass": 88776.0, "length": 796, "protein_name": "Serine/threonine-protein kinase MARK1", "gene_name": "MARK1", "organism": "Pig", "refseq_name": "serine/threonine-protein kinase MARK1 isoform X1", "refseq_ac": "XP_020919987", "gene_names_uniprotkb": "MARK1", "gene_names_refseq": "MARK1", "protein_names_uniprotkb": "Serine/threonine-protein kinase MARK1; 2.7.11.1; 2.7.11.26; MAP/microtubule affinity-regulating kinase 1", "protein_names_refseq": "serine/threonine-protein kinase MARK1 isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100624523)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Serine/threonine-protein kinase. Involved in cell polarity and microtubule dynamics regulation. Phosphorylates DCX, MAP2 and MAP4. Phosphorylates the microtubule-associated protein MAPT/TAU. Involved in cell polarity by phosphorylating the microtubule-associated proteins MAP2, MAP4 and MAPT/TAU at KXGS motifs, causing detachment from microtubules, and their disassembly. Involved in the regulation of neuronal migration through its dual activities in regulating cellular polarity and microtubule dynamics, possibly by phosphorylating and regulating DCX. Also acts as a positive regulator of the Wnt signaling pathway, probably by mediating phosphorylation of dishevelled proteins (DVL1, DVL2 and/or DVL3)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0106310 protein serine kinase activity;GO:0046872 metal ion binding;GO:0008289 lipid binding", "go_cellular_component": "GO:0042995 cell projection;GO:0005856 cytoskeleton;GO:0030425 dendrite;GO:0098978 glutamatergic synapse;GO:0005737 cytoplasm", "go_biological_process": "GO:0016055 Wnt signaling pathway;GO:0035556 intracellular signal transduction;GO:0050773 regulation of dendrite development;GO:0010719 negative regulation of epithelial to mesenchymal transition;GO:0051654 establishment of mitochondrion localization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "I3LBZ2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SPE0-1", "uniprot_id": "F1SPE0_PIG", "mass": 27814.0, "length": 247, "protein_name": "C-type lectin domain containing 7A", "gene_name": "CLEC7A", "organism": "Pig", "refseq_name": "C-type lectin domain family 7 member A isoform 1", "refseq_ac": "NP_001422262", "gene_names_uniprotkb": "CLEC7A", "gene_names_refseq": "CLEC7A", "protein_names_uniprotkb": "C-type lectin domain containing 7A", "protein_names_refseq": "C-type lectin domain family 7 member A isoform 1; C-type lectin domain family 7 member A; dectin 1", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-5607764)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "25453580;26762386;32543654", "class_list": "", "function": "Recognition of beta-glucans appeared cell type-specific as both dectin-1 and CR3 are involved in the beta-glucan-mediated responses in pig macrophages., [RefSeq, PubMed]; These results suggest that functionally neutral polymorphisms in dectin-1 are widespread in pig populations, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0001872 (1->3)-beta-D-glucan binding;GO:0038187 pattern recognition receptor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0009986 cell surface", "go_biological_process": "GO:0071226 cellular response to molecule of fungal origin;GO:0016046 detection of fungus;GO:0008284 positive regulation of cell population proliferation;GO:0030335 positive regulation of cell migration;GO:0032930 positive regulation of superoxide anion generation", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "F1SPE0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SL45-1", "uniprot_id": "F1SL45_PIG", "mass": 28402.0, "length": 248, "protein_name": "Inhibitor of growth protein", "gene_name": "ACRBP; ING4", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "ACRBP; ING4; ING4", "gene_names_refseq": "", "protein_names_uniprotkb": "Inhibitor of growth protein", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-3214847)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Component of an histone acetyltransferase complex., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0043997 histone H4K12 acetyltransferase activity;GO:0003713 transcription coactivator activity;GO:0043995 histone H4K5 acetyltransferase activity;GO:0043996 histone H4K8 acetyltransferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0000123 histone acetyltransferase complex", "go_biological_process": "GO:0006325 chromatin organization;GO:2000278 regulation of DNA biosynthetic process;GO:0008285 negative regulation of cell population proliferation;GO:0043065 positive regulation of apoptotic process;GO:0006355 regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SL45-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1S4N3-1", "uniprot_id": "F1S4N3_PIG", "mass": 175427.0, "length": 1547, "protein_name": "Lysine-specific demethylase 5B", "gene_name": "KDM5B", "organism": "Pig", "refseq_name": "lysine-specific demethylase 5B", "refseq_ac": "XP_020920226", "gene_names_uniprotkb": "KDM5B", "gene_names_refseq": "KDM5B", "protein_names_uniprotkb": "Lysine-specific demethylase 5B; 1.14.11.67; Histone demethylase JARID1B; Jumonji/ARID domain-containing protein 1B; PLU-1; [histone H3]-trimethyl-L-lysine(4) demethylase 5B", "protein_names_refseq": "lysine-specific demethylase 5B", "tax_id": 9823, "disease": "", "pathway": " (ssc:102163404); (R-SSC-3214842); (R-SSC-8866911)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "M3V7Y2", "ec_number_list": "", "go_molecular_function": "GO:0034647 histone H3K4me/H3K4me2/H3K4me3 demethylase activity;GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0003714 transcription corepressor activity;GO:0008168 methyltransferase activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005634 nucleus;GO:0000785 chromatin;GO:1990904 ribonucleoprotein complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045892 negative regulation of DNA-templated transcription;GO:0048511 rhythmic process;GO:0006338 chromatin remodeling;GO:0006355 regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1S4N3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1RYN4-1", "uniprot_id": "F1RYN4_PIG", "mass": 81746.0, "length": 729, "protein_name": "Transporter", "gene_name": "SLC6A15", "organism": "Pig", "refseq_name": "sodium-dependent neutral amino acid transporter B(0)AT2", "refseq_ac": "XP_020948455", "gene_names_uniprotkb": "SLC6A15", "gene_names_refseq": "SLC6A15", "protein_names_uniprotkb": "Transporter", "protein_names_refseq": "sodium-dependent neutral amino acid transporter B(0)AT2", "tax_id": 9823, "disease": "", "pathway": " (ssc:100628231); (R-SSC-352230); (R-SSC-442660)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0046872 metal ion binding;GO:0015293 symporter activity;GO:0005298 proline:sodium symporter activity;GO:0005295 neutral L-amino acid:sodium symporter activity;GO:0015657 branched-chain amino acid:sodium symporter activity", "go_cellular_component": "GO:0016020 membrane;GO:0005886 plasma membrane", "go_biological_process": "GO:0015820 L-leucine transport;GO:0015824 proline transport;GO:0035725 sodium ion transmembrane transport;GO:0006836 neurotransmitter transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1RYN4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P01219-1", "uniprot_id": "GLHA_PIG", "mass": 13532.0, "length": 120, "protein_name": "Glycoprotein hormones alpha chain", "gene_name": "CGA", "organism": "Pig", "refseq_name": "glycoprotein hormones alpha chain precursor", "refseq_ac": "NP_999611", "gene_names_uniprotkb": "CGA", "gene_names_refseq": "CGA", "protein_names_uniprotkb": "Glycoprotein hormones alpha chain; Anterior pituitary glycoprotein hormones common subunit alpha; FSH-alpha; Follicle-stimulating hormone alpha chain; Follitropin alpha chain; LSH-alpha; Luteinizing hormone alpha chain; Lutropin alpha chain; TSH-alpha; Thyroid-stimulating hormone alpha chain; Thyrotropin alpha chain", "protein_names_refseq": "FSH-alpha; LSH-alpha; TSH-alpha; anterior pituitary glycoprotein hormones common subunit alpha; follicle-stimulating hormone alpha chain; follitropin alpha chain; glycoprotein hormones alpha chain precursor; glycoprotein hormones alpha chain; luteinizing hormone alpha chain; lutropin alpha chain; pituitary glycoprotein hormone alpha subunit; thyroid-stimulating hormone alpha chain; thyrotropin alpha chain", "tax_id": 9823, "disease": "", "pathway": " (ssc:406869); (R-SSC-193048); (R-SSC-193993); (R-SSC-209822); (R-SSC-209968); (R-SSC-375281); (R-SSC-8866910); (R-SSC-975578)", "pathway_count": 8, "publication_count": 4, "publication_id_list": "2473932;32543654;4448287;4770796", "class_list": "", "function": "Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH and follitropin/follicle stimulating hormone/FSH. These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 2, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 2, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 2, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0016913 follicle-stimulating hormone activity;GO:0005179 hormone activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0016914 follicle-stimulating hormone complex;GO:0005576 extracellular region", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway;GO:0010469 regulation of signaling receptor activity;GO:0010893 positive regulation of steroid biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P01219-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P31950-1", "uniprot_id": "S10AB_PIG", "mass": 11180.0, "length": 99, "protein_name": "Protein S100-A11", "gene_name": "S100A11", "organism": "Pig", "refseq_name": "protein S100-A11", "refseq_ac": "NP_001004045", "gene_names_uniprotkb": "S100A11; S100C", "gene_names_refseq": "S100A11", "protein_names_uniprotkb": "Protein S100-A11; Calgizzarin; Protein S100-C; S100 calcium-binding protein A11", "protein_names_refseq": "S100C protein; calgizzarin; protein S100-A11; protein S100-C", "tax_id": 9823, "disease": "", "pathway": " (ssc:445534); (R-SSC-6798695)", "pathway_count": 2, "publication_count": 4, "publication_id_list": "10673436;1722468;32543654;9500989", "class_list": "", "function": "Facilitates the differentiation and the cornification of keratinocytes., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0048306 calcium-dependent protein binding;GO:0005509 calcium ion binding;GO:0044548 S100 protein binding;GO:0042803 protein homodimerization activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0016607 nuclear speck;GO:0001726 ruffle", "go_biological_process": "GO:0042127 regulation of cell population proliferation;GO:0014911 positive regulation of smooth muscle cell migration", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P31950-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F6Q7E6-1", "uniprot_id": "F6Q7E6_PIG", "mass": 51287.0, "length": 459, "protein_name": "Interleukin-1 receptor-associated kinase 4", "gene_name": "IRAK4", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "IRAK4", "gene_names_refseq": "", "protein_names_uniprotkb": "Interleukin-1 receptor-associated kinase 4; 2.7.11.1", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-1257604); (R-SSC-6811558); (R-SSC-9020702)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Serine/threonine-protein kinase that plays a critical role in initiating innate immune response against foreign pathogens., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0019901 protein kinase binding;GO:0005149 interleukin-1 receptor binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0009986 cell surface", "go_biological_process": "GO:0070498 interleukin-1-mediated signaling pathway;GO:0035556 intracellular signal transduction;GO:0045087 innate immune response;GO:0002446 neutrophil mediated immunity;GO:0043123 positive regulation of canonical NF-kappaB signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F6Q7E6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P63298-1", "uniprot_id": "SECR_PIG", "mass": 14581.0, "length": 134, "protein_name": "Secretin", "gene_name": "SCT", "organism": "Pig", "refseq_name": "secretin precursor", "refseq_ac": "XP_003122439", "gene_names_uniprotkb": "SCT", "gene_names_refseq": "SCT", "protein_names_uniprotkb": "Secretin", "protein_names_refseq": "secretin precursor", "tax_id": 9823, "disease": "", "pathway": " (ssc:397464)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "2315322;2395872;2831051;2883029;32543654;5465996;5978238;8618828", "class_list": "", "function": "Hormone involved in different processes, such as regulation of the pH of the duodenal content, food intake and water homeostasis. Exerts its biological effects by binding to secretin receptor (SCTR), a G protein-coupled receptor expressed in the basolateral domain of several cells. Acts as a key gastrointestinal hormone by regulating the pH of the duodenal content. Secreted by S cells of the duodenum in the crypts of Lieberkuehn and regulates the pH of the duodenum by (1) inhibiting the secretion of gastric acid from the parietal cells of the stomach and (2) stimulating the production of bicarbonate (NaHCO(3)) from the ductal cells of the pancreas (By similarity). Production of bicarbonate is essential to neutralize the pH and ensure no damage is done to the small intestine by the gastric acid. In addition to regulating the pH of the duodenal content, plays a central role in diet induced thermogenesis: acts as a non-sympathetic brown fat (BAT) activator mediating prandial thermogenesis, which consequentially induces satiation. Mechanistically, secretin released by the gut after a meal binds to secretin receptor (SCTR) in brown adipocytes, activating brown fat thermogenesis by stimulating lipolysis, which is sensed in the brain and promotes satiation. Also able to stimulate lipolysis in white adipocytes (By similarity). Also plays an important role in cellular osmoregulation: released into the systemic circulation in response to hyperosmolality and acts at different levels in the hypothalamus, pituitary and kidney to regulate water homeostasis (By similarity). Also plays a role in the central nervous system, possibly by acting as a neuropeptide hormone: required for hippocampal synaptic function and neural progenitor cells maintenance (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A286ZRG5;P01279;Q9TR13", "ec_number_list": "", "go_molecular_function": "GO:0001664 G protein-coupled receptor binding;GO:0005179 hormone activity;GO:0046659 digestive hormone activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005576 extracellular region", "go_biological_process": "GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0021766 hippocampus development;GO:0031667 response to nutrient levels;GO:0032098 regulation of appetite;GO:0048167 regulation of synaptic plasticity", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P63298-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1S082-1", "uniprot_id": "F1S082_PIG", "mass": 34155.0, "length": 328, "protein_name": "Distal-less homeobox 2", "gene_name": "DLX2", "organism": "Pig", "refseq_name": "homeobox protein DLX-2", "refseq_ac": "XP_003133525", "gene_names_uniprotkb": "DLX2", "gene_names_refseq": "DLX2", "protein_names_uniprotkb": "Distal-less homeobox 2", "protein_names_refseq": "homeobox protein DLX-2", "tax_id": 9823, "disease": "", "pathway": " (ssc:100523029)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0003682 chromatin binding;GO:0003727 single-stranded RNA binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0046533 negative regulation of photoreceptor cell differentiation;GO:1902871 positive regulation of amacrine cell differentiation;GO:0006357 regulation of transcription by RNA polymerase II;GO:0030154 cell differentiation;GO:0048706 embryonic skeletal system development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1S082-1", "record_type": "protein" }, { "uniprot_canonical_ac": "K7GP28-1", "uniprot_id": "K7GP28_PIG", "mass": 30788.0, "length": 293, "protein_name": "3-hydroxyacyl-CoA dehydrogenase type-2", "gene_name": "HSD17B10", "organism": "Pig", "refseq_name": "3-hydroxyacyl-CoA dehydrogenase type-2 isoform X1", "refseq_ac": "XP_003135175", "gene_names_uniprotkb": "HSD17B10", "gene_names_refseq": "HSD17B10", "protein_names_uniprotkb": "3-hydroxyacyl-CoA dehydrogenase type-2; 1.1.1.159; 1.1.1.178; 1.1.1.239; 1.1.1.35; 1.1.1.53; 1.1.1.62; 17-beta-estradiol 17-dehydrogenase; 2-methyl-3-hydroxybutyryl-CoA dehydrogenase; 3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+)); 3-hydroxy-2-methylbutyryl-CoA dehydrogenase; 3-hydroxyacyl-CoA dehydrogenase type II; 3alpha(or 20beta)-hydroxysteroid dehydrogenase; 7-alpha-hydroxysteroid dehydrogenase; Endoplasmic reticulum-associated amyloid beta-peptide-binding protein; Mitochondrial ribonuclease P protein 2; Short chain dehydrogenase/reductase family 5C member 1; Short-chain type dehydrogenase/reductase XH98G2; Type II HADH", "protein_names_refseq": "3-hydroxyacyl-CoA dehydrogenase type-2 isoform X1", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-70895); (R-SSC-9837999)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004303 estradiol 17-beta-dehydrogenase [NAD(P)+] activity;GO:0047035 testosterone dehydrogenase (NAD+) activity;GO:0003857 (3S)-3-hydroxyacyl-CoA dehydrogenase (NAD+) activity;GO:0008709 cholate 7-alpha-dehydrogenase (NAD+) activity;GO:0047015 3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0042645 mitochondrial nucleoid;GO:0030678 mitochondrial ribonuclease P complex", "go_biological_process": "GO:0006629 lipid metabolic process;GO:0008210 estrogen metabolic process;GO:0062173 brexanolone metabolic process;GO:0006631 fatty acid metabolic process;GO:0006635 fatty acid beta-oxidation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "K7GP28-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SGM5-1", "uniprot_id": "F1SGM5_PIG", "mass": 104443.0, "length": 951, "protein_name": "Leucine-rich repeat-containing G-protein coupled receptor 4", "gene_name": "LGR4", "organism": "Pig", "refseq_name": "leucine-rich repeat-containing G-protein coupled receptor 4 isoform X1", "refseq_ac": "XP_020938892", "gene_names_uniprotkb": "LGR4", "gene_names_refseq": "LGR4", "protein_names_uniprotkb": "Leucine-rich repeat-containing G-protein coupled receptor 4", "protein_names_refseq": "leucine-rich repeat-containing G-protein coupled receptor 4 isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100518646); (R-SSC-4641263)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0016500 protein-hormone receptor activity;GO:0004930 G protein-coupled receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0030154 cell differentiation;GO:0016055 Wnt signaling pathway;GO:0048511 rhythmic process;GO:0007283 spermatogenesis;GO:0046849 bone remodeling", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SGM5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1S5K9-1", "uniprot_id": "F1S5K9_PIG", "mass": 96393.0, "length": 870, "protein_name": "Hypoxia-inducible factor 1-alpha", "gene_name": "EPAS1", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "EPAS1", "gene_names_refseq": "", "protein_names_uniprotkb": "Hypoxia-inducible factor 1-alpha", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-1234158); (R-SSC-1234174); (R-SSC-1234176); (R-SSC-8951664)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0046983 protein dimerization activity;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0046982 protein heterodimerization activity;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005667 transcription regulator complex;GO:0016607 nuclear speck", "go_biological_process": "GO:0001525 angiogenesis;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0001974 blood vessel remodeling;GO:0030324 lung development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1S5K9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "K7GT64-1", "uniprot_id": "K7GT64_PIG", "mass": 184682.0, "length": 1647, "protein_name": "SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4", "gene_name": "SMARCA4", "organism": "Pig", "refseq_name": "transcription activator BRG1 isoform X14", "refseq_ac": "XP_020939501", "gene_names_uniprotkb": "SMARCA4", "gene_names_refseq": "SMARCA4", "protein_names_uniprotkb": "SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4", "protein_names_refseq": "transcription activator BRG1 isoform X14", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-1266695); (R-SSC-201722); (R-SSC-3214858); (R-SSC-3247509); (R-SSC-8939243); (R-SSC-9764725); (R-SSC-9933937); (R-SSC-9933939); (R-SSC-9933946); (R-SSC-9933947)", "pathway_count": 10, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A480IZH5", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0016787 hydrolase activity;GO:0042393 histone binding;GO:0003677 DNA binding;GO:0003682 chromatin binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0016514 SWI/SNF complex;GO:0005634 nucleus;GO:0071564 npBAF complex;GO:0001650 fibrillar center", "go_biological_process": "GO:0006338 chromatin remodeling;GO:0006351 DNA-templated transcription;GO:0007399 nervous system development;GO:0006355 regulation of DNA-templated transcription;GO:1902661 positive regulation of glucose mediated signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "K7GT64-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P67937-1", "uniprot_id": "TPM4_PIG", "mass": 28522.0, "length": 248, "protein_name": "Tropomyosin alpha-4 chain", "gene_name": "TPM4", "organism": "Pig", "refseq_name": "tropomyosin alpha-4 chain", "refseq_ac": "NP_999500", "gene_names_uniprotkb": "TPM4", "gene_names_refseq": "TPM4", "protein_names_uniprotkb": "Tropomyosin alpha-4 chain; Tropomyosin-4", "protein_names_refseq": "tropomyosin alpha-4 chain", "tax_id": 9823, "disease": "", "pathway": " (ssc:397608); (R-SSC-390522); (R-SSC-445355); (R-SSC-9013424)", "pathway_count": 4, "publication_count": 2, "publication_id_list": "14582535;32543654", "class_list": "", "function": "Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments. Binds calcium. Plays a role in platelet biogenesis., [UniProtKB, UniProtKB, UniProtKB]; Upregulation of tropomyosin 4 (TM4) mRNA is a relevant marker of dedifferentiation in vascular smooth muscle cells., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "P07226;Q15659;Q9BU85;Q9H8Q3", "ec_number_list": "", "go_molecular_function": "GO:0042802 identical protein binding;GO:0042803 protein homodimerization activity;GO:0046872 metal ion binding;GO:0046982 protein heterodimerization activity;GO:0051015 actin filament binding", "go_cellular_component": "GO:0005884 actin filament;GO:0015629 actin cytoskeleton;GO:0005856 cytoskeleton;GO:0002102 podosome;GO:0001725 stress fiber", "go_biological_process": "GO:0006936 muscle contraction;GO:0007015 actin filament organization;GO:0030220 platelet formation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "P67937-1", "record_type": "protein" }, { "uniprot_canonical_ac": "K7GSR6-1", "uniprot_id": "K7GSR6_PIG", "mass": 62881.0, "length": 574, "protein_name": "5'-nucleotidase", "gene_name": "NT5E", "organism": "Pig", "refseq_name": "5'-nucleotidase", "refseq_ac": "XP_001927130", "gene_names_uniprotkb": "NT5E", "gene_names_refseq": "NT5E", "protein_names_uniprotkb": "5'-nucleotidase; 3.1.3.35; 3.1.3.5; 3.1.3.89; 3.1.3.91; 3.1.3.99; 5'-deoxynucleotidase; Ecto-5'-nucleotidase; IMP-specific 5'-nucleotidase; Thymidylate 5'-phosphatase", "protein_names_refseq": "5'-nucleotidase", "tax_id": 9823, "disease": "", "pathway": " (ssc:100157995); (R-SSC-196807); (R-SSC-73621); (R-SSC-74259)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0046872 metal ion binding;GO:0000166 nucleotide binding;GO:0008253 5'-nucleotidase activity;GO:0008270 zinc ion binding;GO:0042802 identical protein binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0009897 external side of plasma membrane", "go_biological_process": "GO:0009166 nucleotide catabolic process;GO:0046032 ADP catabolic process;GO:0006196 AMP catabolic process;GO:0007159 leukocyte cell-cell adhesion;GO:0031214 biomineral tissue development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "K7GSR6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1S0Z3-1", "uniprot_id": "F1S0Z3_PIG", "mass": 99737.0, "length": 894, "protein_name": "Microsomal triglyceride transfer protein large subunit", "gene_name": "MTTP", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "MTTP", "gene_names_refseq": "", "protein_names_uniprotkb": "Microsomal triglyceride transfer protein large subunit", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Catalyzes the transport of triglyceride, cholesteryl ester, and phospholipid between phospholipid surfaces. Required for the assembly and secretion of plasma lipoproteins that contain apolipoprotein B. May be involved in regulating cholesteryl ester biosynthesis in cells that produce lipoproteins., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008289 lipid binding;GO:1904121 phosphatidylethanolamine transfer activity;GO:0120020 cholesterol transfer activity;GO:0140344 triglyceride transfer activity;GO:0046982 protein heterodimerization activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0016323 basolateral plasma membrane;GO:0043235 receptor complex", "go_biological_process": "GO:0042157 lipoprotein metabolic process;GO:0042632 cholesterol homeostasis;GO:0007623 circadian rhythm;GO:0009306 protein secretion;GO:0034197 triglyceride transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1S0Z3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P00172-1", "uniprot_id": "CYB5_PIG", "mass": 15310.0, "length": 134, "protein_name": "Cytochrome b5", "gene_name": "CYB5A", "organism": "Pig", "refseq_name": "cytochrome b5", "refseq_ac": "NP_001001770", "gene_names_uniprotkb": "CYB5A; CYB5", "gene_names_refseq": "CYB5A", "protein_names_uniprotkb": "Cytochrome b5", "protein_names_refseq": "cytochrome b5 type A (microsomal); cytochrome b5", "tax_id": 9823, "disease": "", "pathway": " (ssc:414799); (R-SSC-196836); (R-SSC-9609523)", "pathway_count": 3, "publication_count": 10, "publication_id_list": "16104384;18162105;19101629;269425;2752049;32543654;4030743;4810060;4993957;9367886", "class_list": "", "function": "Cytochrome b5 is a membrane-bound hemoprotein functioning as an electron carrier for several membrane-bound oxygenases., [UniProtKB]; Searching the porcine CYB5 gene for mutations, examine its expression, and identify genetic polymorphism in terms of androstenone levels in testis., [RefSeq, PubMed]; The c.-8G>T SNP in the CYB5A gene has a significant but modest effect on boar taint in male pigs and could be useful in some breeds as part of a panel of SNP markers in a marker-assisted selection programme to produce low boar taint pigs, [RefSeq, PubMed]; These results demonstrate the differential effects of two forms of CYB5 on the three activities of porcine CYP17A1 and show that CYB5B does not stimulate the andien-beta synthase activity of CYP17A1., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "O18813", "ec_number_list": "", "go_molecular_function": "GO:0046872 metal ion binding;GO:0020037 heme binding;GO:0019899 enzyme binding", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane;GO:0005783 endoplasmic reticulum;GO:0005829 cytosol;GO:0016020 membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "P00172-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SML7-1", "uniprot_id": "F1SML7_PIG", "mass": 61316.0, "length": 571, "protein_name": "Inosine-5'-monophosphate dehydrogenase", "gene_name": "IMPDH1", "organism": "Pig", "refseq_name": "inosine-5'-monophosphate dehydrogenase 1 isoform X1", "refseq_ac": "XP_020934368", "gene_names_uniprotkb": "IMPDH1; IMPDH", "gene_names_refseq": "IMPDH1", "protein_names_uniprotkb": "Inosine-5'-monophosphate dehydrogenase; 1.1.1.205; IMP dehydrogenase; IMPDH; IMPD", "protein_names_refseq": "inosine-5'-monophosphate dehydrogenase 1 isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100520873); (R-SSC-6798695); (R-SSC-73817); (R-SSC-9748787)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors., [UniProtKB, HAMAP, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0046872 metal ion binding;GO:0000166 nucleotide binding;GO:0003938 IMP dehydrogenase activity;GO:0003677 DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0006177 GMP biosynthetic process;GO:0006183 GTP biosynthetic process;GO:0097294 'de novo' XMP biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SML7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1RYR0-1", "uniprot_id": "F1RYR0_PIG", "mass": 102495.0, "length": 908, "protein_name": "Glutamate receptor", "gene_name": "GRIK2", "organism": "Pig", "refseq_name": "glutamate receptor ionotropic, kainate 2 isoform X1", "refseq_ac": "XP_020928995", "gene_names_uniprotkb": "GRIK2", "gene_names_refseq": "GRIK2", "protein_names_uniprotkb": "Glutamate receptor", "protein_names_refseq": "glutamate receptor ionotropic, kainate 2 isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100516526); (R-SSC-451307); (R-SSC-451308)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0015276 ligand-gated monoatomic ion channel activity;GO:0038023 signaling receptor activity;GO:0022849 glutamate-gated calcium ion channel activity;GO:0005234 extracellularly glutamate-gated ion channel activity;GO:0015277 kainate selective glutamate receptor activity", "go_cellular_component": "GO:0045211 postsynaptic membrane;GO:0098978 glutamatergic synapse;GO:0005886 plasma membrane;GO:0043025 neuronal cell body;GO:0042734 presynaptic membrane", "go_biological_process": "GO:0048172 regulation of short-term neuronal synaptic plasticity;GO:0035249 synaptic transmission, glutamatergic;GO:0050804 modulation of chemical synaptic transmission;GO:0050806 positive regulation of synaptic transmission;GO:0120169 detection of cold stimulus involved in thermoception", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1RYR0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "I3L704-1", "uniprot_id": "I3L704_PIG", "mass": 33377.0, "length": 313, "protein_name": "Anamorsin", "gene_name": "CIAPIN1", "organism": "Pig", "refseq_name": "anamorsin", "refseq_ac": "XP_003355851", "gene_names_uniprotkb": "CIAPIN1", "gene_names_refseq": "CIAPIN1", "protein_names_uniprotkb": "Anamorsin; Cytokine-induced apoptosis inhibitor 1; Fe-S cluster assembly protein DRE2 homolog", "protein_names_refseq": "anamorsin", "tax_id": 9823, "disease": "", "pathway": " (ssc:100620929)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex NUBP1-NUBP2. Electrons are transferred to CIAPIN1 from NADPH via the FAD- and FMN-containing protein NDOR1. NDOR1-CIAPIN1 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit. Has anti-apoptotic effects in the cell. Involved in negative control of cell death upon cytokine withdrawal. Promotes development of hematopoietic cells., [UniProtKB, UniProtKB, UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0046872 metal ion binding;GO:0051539 4 iron, 4 sulfur cluster binding;GO:0051537 2 iron, 2 sulfur cluster binding;GO:0009055 electron transfer activity", "go_cellular_component": "GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0005654 nucleoplasm;GO:0005758 mitochondrial intermembrane space;GO:0005829 cytosol", "go_biological_process": "GO:0016226 iron-sulfur cluster assembly;GO:0006915 apoptotic process;GO:0043066 negative regulation of apoptotic process;GO:0030097 hemopoiesis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "I3L704-1", "record_type": "protein" }, { "uniprot_canonical_ac": "I3L6S5-1", "uniprot_id": "I3L6S5_PIG", "mass": 125268.0, "length": 1145, "protein_name": "Phosphodiesterase", "gene_name": "PDE3A", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "PDE3A", "gene_names_refseq": "", "protein_names_uniprotkb": "Phosphodiesterase; 3.1.4.-", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-418555)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0046872 metal ion binding;GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity;GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity;GO:0004119 3',5'-cGMP-inhibited cyclic-nucleotide phosphodiesterase activity;GO:0030284 nuclear estrogen receptor activity", "go_cellular_component": "GO:0016020 membrane;GO:0005829 cytosol", "go_biological_process": "GO:0007165 signal transduction;GO:0043116 negative regulation of vascular permeability;GO:0097190 apoptotic signaling pathway;GO:0071560 cellular response to transforming growth factor beta stimulus;GO:0043117 positive regulation of vascular permeability", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "I3L6S5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SCY7-1", "uniprot_id": "F1SCY7_PIG", "mass": 40029.0, "length": 354, "protein_name": "Tumor necrosis factor receptor superfamily member 6", "gene_name": "FAS", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "FAS", "gene_names_refseq": "", "protein_names_uniprotkb": "Tumor necrosis factor receptor superfamily member 6; Apo-1 antigen; Apoptosis-mediating surface antigen FAS; FASLG receptor", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-3371378); (R-SSC-5218900); (R-SSC-69416); (R-SSC-75157)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004888 transmembrane signaling receptor activity;GO:0005516 calmodulin binding;GO:0042802 identical protein binding;GO:0019900 kinase binding;GO:0005031 tumor necrosis factor receptor activity", "go_cellular_component": "GO:0009986 cell surface;GO:0045121 membrane raft;GO:0031265 CD95 death-inducing signaling complex;GO:0009897 external side of plasma membrane", "go_biological_process": "GO:0006955 immune response;GO:0042981 regulation of apoptotic process;GO:0097191 extrinsic apoptotic signaling pathway;GO:0043066 negative regulation of apoptotic process;GO:2001235 positive regulation of apoptotic signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SCY7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1S9C0-1", "uniprot_id": "F1S9C0_PIG", "mass": 14697.0, "length": 133, "protein_name": "Serum amyloid A protein", "gene_name": "SAA2", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "SAA2", "gene_names_refseq": "", "protein_names_uniprotkb": "Serum amyloid A protein", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Major acute phase reactant. 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ADP,ATP carrier protein", "protein_names_refseq": "ADP/ATP translocase 2", "tax_id": 9823, "disease": "", "pathway": " (ssc:100158185); (R-SSC-83936); (R-SSC-9837999)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Catalyzes the exchange of ADP and ATP across the membrane., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005471 ATP:ADP antiporter activity;GO:0031625 ubiquitin protein ligase binding;GO:0015078 proton transmembrane transporter activity;GO:0017077 oxidative phosphorylation uncoupler activity", "go_cellular_component": "GO:0005743 mitochondrial inner membrane;GO:0042645 mitochondrial nucleoid;GO:0071817 MMXD complex;GO:0005757 mitochondrial permeability transition pore complex", "go_biological_process": "GO:0007059 chromosome segregation;GO:0140021 mitochondrial ADP transmembrane transport;GO:1990544 mitochondrial ATP transmembrane transport;GO:1901526 positive regulation of mitophagy;GO:0008284 positive regulation of cell population proliferation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F2Z565-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SBK4-1", "uniprot_id": "F1SBK4_PIG", "mass": 61942.0, "length": 570, "protein_name": "Molecular chaperone MKKS", "gene_name": "MKKS", "organism": "Pig", "refseq_name": "McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin", "refseq_ac": "XP_001928819", "gene_names_uniprotkb": "MKKS", "gene_names_refseq": "MKKS", "protein_names_uniprotkb": "Molecular chaperone MKKS; 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Plays a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. May play a role in protein processing in limb, cardiac and reproductive system development. 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Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005031 tumor necrosis factor receptor activity;GO:0019955 cytokine binding", "go_cellular_component": "GO:0016020 membrane;GO:0045121 membrane raft;GO:0009897 external side of plasma membrane", "go_biological_process": "GO:0010557 positive regulation of macromolecule biosynthetic process;GO:0023035 CD40 signaling pathway;GO:0006952 defense response;GO:0006874 intracellular calcium ion homeostasis;GO:0010468 regulation of gene expression", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "K7GN73-1", "record_type": "protein" }, { "uniprot_canonical_ac": "K7GQY0-1", "uniprot_id": "K7GQY0_PIG", "mass": 93914.0, "length": 839, "protein_name": "Fibroblast growth factor receptor", "gene_name": "FGFR2", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "FGFR2", "gene_names_refseq": "", "protein_names_uniprotkb": "Fibroblast growth factor receptor; 2.7.10.1", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 9, "predicted_n_glycosites": 8, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 9, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005007 fibroblast growth factor receptor activity;GO:0005524 ATP binding;GO:0017134 fibroblast growth factor binding;GO:0042803 protein homodimerization activity", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0005886 plasma membrane;GO:0031410 cytoplasmic vesicle;GO:0005634 nucleus;GO:0005938 cell cortex", "go_biological_process": "GO:0008284 positive regulation of cell population proliferation;GO:0006915 apoptotic process;GO:1904888 cranial skeletal system development;GO:0050680 negative regulation of epithelial cell proliferation;GO:0045595 regulation of cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "K7GQY0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1S5V0-1", "uniprot_id": "F1S5V0_PIG", "mass": 86725.0, "length": 805, "protein_name": "Ubiquitin carboxyl-terminal hydrolase", "gene_name": "USP10", "organism": "Pig", "refseq_name": "ubiquitin carboxyl-terminal hydrolase 10 isoform X1", "refseq_ac": "XP_020949383", "gene_names_uniprotkb": "USP10", "gene_names_refseq": "USP10", "protein_names_uniprotkb": "Ubiquitin carboxyl-terminal hydrolase; 3.4.19.12", "protein_names_refseq": "ubiquitin carboxyl-terminal hydrolase 10 isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100514462); (R-SSC-5656169); (R-SSC-5689880)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004843 cysteine-type deubiquitinase activity;GO:0044325 transmembrane transporter binding;GO:0002039 p53 binding;GO:0004197 cysteine-type endopeptidase activity;GO:0140678 molecular function inhibitor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005654 nucleoplasm;GO:0005769 early endosome;GO:0005829 cytosol", "go_biological_process": "GO:0006281 DNA repair;GO:0006508 proteolysis;GO:0016579 protein deubiquitination;GO:0006914 autophagy;GO:0072344 rescue of stalled ribosome", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1S5V0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SAA9-1", "uniprot_id": "F1SAA9_PIG", "mass": 37377.0, "length": 327, "protein_name": "Ubiquitin carboxyl-terminal hydrolase", "gene_name": "UCHL5", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "UCHL5", "gene_names_refseq": "", "protein_names_uniprotkb": "Ubiquitin carboxyl-terminal hydrolase; 3.4.19.12", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-5689603)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Protease that specifically cleaves 'Lys-48'-linked polyubiquitin chains. Deubiquitinating enzyme associated with the 19S regulatory subunit of the 26S proteasome. Putative regulatory component of the INO80 complex; however is inactive in the INO80 complex and is activated by a transient interaction of the INO80 complex with the proteasome via ADRM1., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0070628 proteasome binding;GO:0004843 cysteine-type deubiquitinase activity;GO:0004866 endopeptidase inhibitor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0031011 Ino80 complex;GO:0000502 proteasome complex;GO:0005654 nucleoplasm;GO:0005730 nucleolus", "go_biological_process": "GO:0006281 DNA repair;GO:0006310 DNA recombination;GO:0006351 DNA-templated transcription;GO:0016579 protein deubiquitination;GO:0006511 ubiquitin-dependent protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SAA9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SUK5-1", "uniprot_id": "F1SUK5_PIG", "mass": 254404.0, "length": 2213, "protein_name": "Myosin VIIA", "gene_name": "MYO7A", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "MYO7A", "gene_names_refseq": "", "protein_names_uniprotkb": "Myosin VIIA", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003779 actin binding;GO:0005524 ATP binding;GO:0003774 cytoskeletal motor activity;GO:0005516 calmodulin binding;GO:0019904 protein domain specific binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0045177 apical part of cell;GO:0005902 microvillus;GO:0016459 myosin complex;GO:0005829 cytosol", "go_biological_process": "GO:0048731 system development;GO:0048513 animal organ development;GO:0009653 anatomical structure morphogenesis;GO:0003008 system process;GO:0007601 visual perception", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SUK5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P02703-1", "uniprot_id": "COL_PIG", "mass": 12140.0, "length": 112, "protein_name": "Colipase", "gene_name": "CLPS", "organism": "Pig", "refseq_name": "colipase precursor", "refseq_ac": "NP_999368", "gene_names_uniprotkb": "CLPS", "gene_names_refseq": "CLPS", "protein_names_uniprotkb": "Colipase; Procolipase II", "protein_names_refseq": "colipase precursor; pancreatic colipase; procolipase II", "tax_id": 9823, "disease": "", "pathway": " (ssc:397407); (R-SSC-192456); (R-SSC-975634)", "pathway_count": 3, "publication_count": 12, "publication_id_list": "10092856;1522902;18052211;18506778;32543654;4603223;4858821;6691986;7773176;7867624;8479519;8663362", "class_list": "", "function": "Analysis of structures of NMR colipase models and simulations of their interactions with various lipid aggregates, lipid droplet, and bile salt micelle, were carried out to determine and to map the lipid binding sites on colipase., [RefSeq, PubMed]; Colipase is a cofactor of pancreatic lipase. It allows the lipase to anchor itself to the lipid-water interface. Without colipase the enzyme is washed off by bile salts, which have an inhibitory effect on the lipase., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Enterostatin has a biological activity as a satiety signal., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Isotropic orientation of colipase which could explain its incapacity to reverse the inhibitory effects of these lipids on the lipase activity, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q3I5G6;Q9N1T6", "ec_number_list": "", "go_molecular_function": "GO:0008047 enzyme activator activity;GO:0035473 lipase binding", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "GO:0001523 retinoid metabolic process;GO:0016042 lipid catabolic process;GO:0007586 digestion", "synthesized_glycan_count": 0, "hit_score": 1.3, "record_id": "P02703-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SFA2-1", "uniprot_id": "F1SFA2_PIG", "mass": 39428.0, "length": 354, "protein_name": "Paraoxonase", "gene_name": "PON2", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "PON2", "gene_names_refseq": "", "protein_names_uniprotkb": "Paraoxonase; 3.1.1.2", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-2142688)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Capable of hydrolyzing lactones and a number of aromatic carboxylic acid esters., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0102007 acyl-L-homoserine-lactone lactonohydrolase activity;GO:0046872 metal ion binding;GO:0004064 arylesterase activity;GO:0042803 protein homodimerization activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0016020 membrane;GO:0005886 plasma membrane", "go_biological_process": "GO:0009636 response to toxic substance;GO:1901335 lactone catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SFA2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SE20-1", "uniprot_id": "F1SE20_PIG", "mass": 63467.0, "length": 561, "protein_name": "Plasminogen activator", "gene_name": "PLAT", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "PLAT", "gene_names_refseq": "", "protein_names_uniprotkb": "Plasminogen activator; 3.4.21.68", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004252 serine-type endopeptidase activity;GO:0005102 signaling receptor binding;GO:0051219 phosphoprotein binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0098978 glutamatergic synapse;GO:0005615 extracellular space;GO:0009986 cell surface;GO:0030141 secretory granule", "go_biological_process": "GO:0031639 plasminogen activation;GO:0014909 smooth muscle cell migration;GO:0045861 negative regulation of proteolysis;GO:0048008 platelet-derived growth factor receptor signaling pathway;GO:0099183 trans-synaptic signaling by BDNF, modulating synaptic transmission", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SE20-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1S0R5-1", "uniprot_id": "F1S0R5_PIG", "mass": 80114.0, "length": 711, "protein_name": "Frizzled-6", "gene_name": "FZD6", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "FZD6", "gene_names_refseq": "", "protein_names_uniprotkb": "Frizzled-6", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-4086398); (R-SSC-4086400); (R-SSC-4641263)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0031625 ubiquitin protein ligase binding;GO:0017147 Wnt-protein binding;GO:0042813 Wnt receptor activity", "go_cellular_component": "GO:0009986 cell surface;GO:0005789 endoplasmic reticulum membrane;GO:0016324 apical plasma membrane;GO:0030659 cytoplasmic vesicle membrane;GO:0005886 plasma membrane", "go_biological_process": "GO:0016055 Wnt signaling pathway;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0090090 negative regulation of canonical Wnt signaling pathway;GO:0060070 canonical Wnt signaling pathway;GO:0035567 non-canonical Wnt signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1S0R5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F2Z4Y3-1", "uniprot_id": "F2Z4Y3_PIG", "mass": 23525.0, "length": 218, "protein_name": "E3 ubiquitin-protein ligase RNF", "gene_name": "LIMK2", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "LIMK2; RNF185", "gene_names_refseq": "", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase RNF; 2.3.2.27; RING finger protein", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-382556); (R-SSC-9931269)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "E3 ubiquitin-protein ligase., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity;GO:0044390 ubiquitin-like protein conjugating enzyme binding;GO:0044877 protein-containing complex binding;GO:0043130 ubiquitin binding", "go_cellular_component": "GO:0031966 mitochondrial membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006511 ubiquitin-dependent protein catabolic process;GO:0051607 defense response to virus;GO:0036503 ERAD pathway;GO:0051865 protein autoubiquitination;GO:1904294 positive regulation of ERAD pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F2Z4Y3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "I3LVJ1-1", "uniprot_id": "I3LVJ1_PIG", "mass": 120270.0, "length": 1066, "protein_name": "Lysine-specific demethylase 4A", "gene_name": "KDM4A", "organism": "Pig", "refseq_name": "lysine-specific demethylase 4A isoform X1", "refseq_ac": "XP_020952494", "gene_names_uniprotkb": "KDM4A", "gene_names_refseq": "KDM4A", "protein_names_uniprotkb": "Lysine-specific demethylase 4A; 1.14.11.66; 1.14.11.69; JmjC domain-containing histone demethylation protein 3A; Jumonji domain-containing protein 2A; [histone H3]-trimethyl-L-lysine(36) demethylase 4A; [histone H3]-trimethyl-L-lysine(9) demethylase 4A", "protein_names_refseq": "lysine-specific demethylase 4A isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100621904); (R-SSC-3214842); (R-SSC-5693565)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "I3LQ64", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0140684 histone H3K9me2/H3K9me3 demethylase activity;GO:0140681 histone H3K36me2/H3K36me3 demethylase activity;GO:0051864 histone H3K36 demethylase activity;GO:0031625 ubiquitin protein ligase binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0001650 fibrillar center;GO:0000785 chromatin;GO:0005721 pericentric heterochromatin", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006338 chromatin remodeling;GO:0010629 negative regulation of gene expression;GO:0045892 negative regulation of DNA-templated transcription;GO:0010507 negative regulation of autophagy", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "I3LVJ1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q5S1S4-1", "uniprot_id": "CAH3_PIG", "mass": 29411.0, "length": 260, "protein_name": "Carbonic anhydrase 3", "gene_name": "CA3", "organism": "Pig", "refseq_name": "carbonic anhydrase 3", "refseq_ac": "NP_001008688", "gene_names_uniprotkb": "CA3", "gene_names_refseq": "CA3", "protein_names_uniprotkb": "Carbonic anhydrase 3; 4.2.1.1; CA-III; Carbonate dehydratase III; Carbonic anhydrase III", "protein_names_refseq": "CA-III; carbonate dehydratase III; carbonic anhydrase 3; carbonic anhydrase III, muscle specific", "tax_id": 9823, "disease": "", "pathway": " (ssc:494016)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "17065793;18298937;23398130;32543654", "class_list": "", "function": "Molecular characterization revealed that CA3 genomic DNA consists of seven exons and six introns, spans about 10.5 kb and maps to porcine chromosome 4q11-->q14., [RefSeq, PubMed]; Reversible hydration of carbon dioxide., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; The temporal and spatial distributions of CA3 gene product were analysed and the association between the presence of specific polymorphisms and carcass traits in the pig was also examined., [RefSeq, PubMed]; These results demonstrated that CA-III is bound to the transferrin and albumin, and that its levels were higher in diseased swine compared with the healthy pigs., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 9, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q0Z809", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0004089 carbonate dehydratase activity", "go_cellular_component": "GO:0005829 cytosol;GO:0005737 cytoplasm", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q5S1S4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "O19004-1", "uniprot_id": "ARAF_PIG", "mass": 67538.0, "length": 606, "protein_name": "Serine/threonine-protein kinase A-Raf", "gene_name": "ARAF", "organism": "Pig", "refseq_name": "serine/threonine-protein kinase A-Raf", "refseq_ac": "NP_999494", "gene_names_uniprotkb": "ARAF; ARAF1", "gene_names_refseq": "ARAF1; ARAF", "protein_names_uniprotkb": "Serine/threonine-protein kinase A-Raf; 2.7.11.1; Proto-oncogene A-Raf-1; Proto-oncogene A-Raf", "protein_names_refseq": "A-Raf proto-oncogene serine/threonine-protein kinase; A-Raf-1; proto-oncogene A-Raf-1; proto-oncogene A-Raf; serine/threonine-protein kinase A-Raf; v-raf murine sarcoma 3611 viral oncogene homolog", "tax_id": 9823, "disease": "", "pathway": " (ssc:397601); (R-SSC-5673000); (R-SSC-5674135); (R-SSC-5675221)", "pathway_count": 4, "publication_count": 3, "publication_id_list": "32543654;37858158;9166601", "class_list": "", "function": "Involved in the transduction of mitogenic signals from the cell membrane to the nucleus. May also regulate the TOR signaling cascade (By similarity). Phosphorylates PFKFB2 (By similarity)., [UniProtKB, UniProtKB]; Toxoplasma gondii infection regulates apoptosis of host cells via miR-185/ARAF axis. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 7, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0008270 zinc ion binding;GO:0004709 MAP kinase kinase kinase activity;GO:0106310 protein serine kinase activity;GO:0004674 protein serine/threonine kinase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005829 cytosol;GO:0005886 plasma membrane", "go_biological_process": "GO:0000165 MAPK cascade;GO:0032006 regulation of TOR signaling;GO:0032434 regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0007165 signal transduction;GO:0043066 negative regulation of apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "O19004-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P04101-1", "uniprot_id": "HSP1_PIG", "mass": 6559.0, "length": 50, "protein_name": "Sperm protamine P1", "gene_name": "PRM1", "organism": "Pig", "refseq_name": "sperm protamine P1", "refseq_ac": "NP_999418", "gene_names_uniprotkb": "PRM1; PRM-1", "gene_names_refseq": "PRM-1; PRM1", "protein_names_uniprotkb": "Sperm protamine P1; Cysteine-rich protamine", "protein_names_refseq": "P1-protamine; cysteine-rich protamine; sperm protamine P1", "tax_id": 9823, "disease": "", "pathway": " (ssc:397487)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "1627265;18462614;3211757;32543654;8240358", "class_list": "", "function": "Porcine spermatozoa may delivery CLU, PRM1 and PRM2 mRNAs to the oocyte, which may contribute to zygotic and early embryonic development., [RefSeq, PubMed]; Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis. They compact sperm DNA into a highly condensed, stable and inactive complex., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0000786 nucleosome", "go_biological_process": "GO:0030261 chromosome condensation;GO:0035092 sperm DNA condensation", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P04101-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P86412-1", "uniprot_id": "MYP2_PIG", "mass": 14922.0, "length": 132, "protein_name": "Myelin P2 protein", "gene_name": "PMP2", "organism": "Pig", "refseq_name": "myelin P2 protein", "refseq_ac": "NP_001171994", "gene_names_uniprotkb": "PMP2", "gene_names_refseq": "PMP2", "protein_names_uniprotkb": "Myelin P2 protein", "protein_names_refseq": "myelin P2 protein", "tax_id": 9823, "disease": "", "pathway": " (ssc:100151890)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "15679890;20512566;32543654", "class_list": "", "function": "May play a role in lipid transport protein in Schwann cells. May bind cholesterol (By similarity)., [UniProtKB]; Oleic, stearic, and palmitic fatty acids are associated with P2 myelin protein protein. Erratum:[Anal Bioanal Chem. 2010 Dec;398(7-8):3225-6], [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005504 fatty acid binding;GO:0015485 cholesterol binding;GO:0008289 lipid binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0043209 myelin sheath", "go_biological_process": "GO:0061024 membrane organization", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "P86412-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P27917-1", "uniprot_id": "APOC3_PIG", "mass": 10704.0, "length": 96, "protein_name": "Apolipoprotein C-III", "gene_name": "APOC3", "organism": "Pig", "refseq_name": "apolipoprotein C-III precursor", "refseq_ac": "NP_001002801", "gene_names_uniprotkb": "APOC3", "gene_names_refseq": "APOC3", "protein_names_uniprotkb": "Apolipoprotein C-III; Apo-CIII; ApoC-III; Apolipoprotein C3", "protein_names_refseq": "apo-CIII; apoC-III; apolipoprotein C-III precursor; apolipoprotein C-III", "tax_id": 9823, "disease": "", "pathway": " (ssc:406187); (R-SSC-8963888); (R-SSC-8963901); (R-SSC-8964058); (R-SSC-975634)", "pathway_count": 5, "publication_count": 6, "publication_id_list": "15878672;24085428;32543654;8428656;8468059;8672129", "class_list": "", "function": "Changes in apolipoprotein A-I and apo C-III mRNA were reflected in their corresponding plasma levels, [RefSeq, PubMed]; Component of triglyceride-rich very low density lipoproteins (VLDL) and high density lipoproteins (HDL) in plasma. Plays a multifaceted role in triglyceride homeostasis. Intracellularly, promotes hepatic very low density lipoprotein 1 (VLDL1) assembly and secretion; extracellularly, attenuates hydrolysis and clearance of triglyceride-rich lipoproteins (TRLs). Impairs the lipolysis of TRLs by inhibiting lipoprotein lipase and the hepatic uptake of TRLs by remnant receptors. Formed of several curved helices connected via semiflexible hinges, so that it can wrap tightly around the curved micelle surface and easily adapt to the different diameters of its natural binding partners., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Gene polymorphisms in APOA5 and APOC3 are associated with meat quality traits in Kele pigs Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q29208", "ec_number_list": "", "go_molecular_function": "GO:0005543 phospholipid binding;GO:0055102 lipase inhibitor activity;GO:0070653 high-density lipoprotein particle receptor binding;GO:0008289 lipid binding", "go_cellular_component": "GO:0034363 intermediate-density lipoprotein particle;GO:0034361 very-low-density lipoprotein particle;GO:0034366 spherical high-density lipoprotein particle;GO:0042627 chylomicron", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway;GO:0033700 phospholipid efflux;GO:0042157 lipoprotein metabolic process;GO:0045717 negative regulation of fatty acid biosynthetic process;GO:0033344 cholesterol efflux", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P27917-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q66X52-1", "uniprot_id": "LTOR5_PIG", "mass": 9614.0, "length": 91, "protein_name": "Ragulator complex protein LAMTOR5", "gene_name": "LAMTOR5", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "LAMTOR5", "gene_names_refseq": "", "protein_names_uniprotkb": "Ragulator complex protein LAMTOR5; Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (ssc:448965)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V-ATPase, the Ragulator plays a dual role for the small GTPases Rag (RagA/RRAGA, RagB/RRAGB, RagC/RRAGC and/or RagD/RRAGD): it (1) acts as a guanine nucleotide exchange factor (GEF), activating the small GTPases Rag and (2) mediates recruitment of Rag GTPases to the lysosome membrane. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. When complexed to BIRC5, interferes with apoptosome assembly, preventing recruitment of pro-caspase-9 to oligomerized APAF1, thereby selectively suppressing apoptosis initiated via the mitochondrial/cytochrome c pathway., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0060090 molecular adaptor activity;GO:0005085 guanyl-nucleotide exchange factor activity", "go_cellular_component": "GO:0005829 cytosol;GO:0005764 lysosome;GO:0005765 lysosomal membrane;GO:0071986 Ragulator complex;GO:1990877 FNIP-folliculin RagC/D GAP", "go_biological_process": "GO:1904263 positive regulation of TORC1 signaling;GO:0043066 negative regulation of apoptotic process;GO:0043123 positive regulation of canonical NF-kappaB signal transduction;GO:0032008 positive regulation of TOR signaling;GO:0032757 positive regulation of interleukin-8 production", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q66X52-1", "record_type": "protein" }, { "uniprot_canonical_ac": "O18765-1", "uniprot_id": "S5A2_PIG", "mass": 28536.0, "length": 254, "protein_name": "3-oxo-5-alpha-steroid 4-dehydrogenase 2", "gene_name": "SRD5A2", "organism": "Pig", "refseq_name": "3-oxo-5-alpha-steroid 4-dehydrogenase 2", "refseq_ac": "NP_999153", "gene_names_uniprotkb": "SRD5A2; ST5AR2", "gene_names_refseq": "S5AR 2; SRD5A2; ST5AR2", "protein_names_uniprotkb": "3-oxo-5-alpha-steroid 4-dehydrogenase 2; 1.3.1.22; 5 alpha-SR2; S5AR 2; SR type 2; Steroid 5-alpha-reductase 2", "protein_names_refseq": "3-oxo-5-alpha-steroid 4-dehydrogenase 2; 5 alpha-SR2; SR type 2; cancer, and female hirsutism in Homo sapiens; reduced or excessive levels can cause incomplete differentitation of male external genitalia, prostate", "tax_id": 9823, "disease": "", "pathway": " (ssc:397048)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Catalyzes the irreversible stereospecific reduction of the delta 4,5 bond (double bond between carbons 4 and 5) of various 3-oxo steroids (3-keto steroids) producing their 5alpha dihydro-3-oxo forms. Converts testosterone into 5-alpha-dihydrotestosterone (DHT), the most active androgen in the prostate, as it is the preferred ligand for androgen receptor (AR) transactivation, making this reaction a key step in male sexual differentiation during development. Besides testosterone, it can also act on other steroids, including progesterone, producing metabolites with diverse roles. Hence, it plays a central role in sexual differentiation and androgen physiology., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0047045 testosterone dehydrogenase (NADP+) activity;GO:0047751 3-oxo-5-alpha-steroid 4-dehydrogenase (NADP+) activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0030154 cell differentiation;GO:0008584 male gonad development;GO:0006702 androgen biosynthetic process;GO:0061370 testosterone biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "O18765-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F2Z5F0-1", "uniprot_id": "F2Z5F0_PIG", "mass": 11783.0, "length": 108, "protein_name": "peptidylprolyl isomerase", "gene_name": "FKBP1B", "organism": "Pig", "refseq_name": "peptidyl-prolyl cis-trans isomerase FKBP1B isoform X1", "refseq_ac": "XP_003125413", "gene_names_uniprotkb": "FKBP1B", "gene_names_refseq": "FKBP1B", "protein_names_uniprotkb": "peptidylprolyl isomerase; 5.2.1.8", "protein_names_refseq": "peptidyl-prolyl cis-trans isomerase FKBP1B isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100522131); (R-SSC-2672351); (R-SSC-5578775)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Has the potential to contribute to the immunosuppressive and toxic effects of FK506 and rapamycin. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003755 peptidyl-prolyl cis-trans isomerase activity;GO:0005102 signaling receptor binding;GO:0044325 transmembrane transporter binding;GO:0019855 calcium channel inhibitor activity;GO:0005528 FK506 binding", "go_cellular_component": "GO:0016529 sarcoplasmic reticulum;GO:0030018 Z disc;GO:0034704 calcium channel complex;GO:0033017 sarcoplasmic reticulum membrane", "go_biological_process": "GO:0050849 negative regulation of calcium-mediated signaling;GO:0051280 negative regulation of release of sequestered calcium ion into cytosol;GO:0051775 response to redox state;GO:0010459 negative regulation of heart rate;GO:0006457 protein folding", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F2Z5F0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P79287-1", "uniprot_id": "MMP20_PIG", "mass": 54085.0, "length": 483, "protein_name": "Matrix metalloproteinase-20", "gene_name": "MMP20", "organism": "Pig", "refseq_name": "matrix metalloproteinase-20 precursor", "refseq_ac": "NP_999070", "gene_names_uniprotkb": "MMP20", "gene_names_refseq": "MMP20", "protein_names_uniprotkb": "Matrix metalloproteinase-20; 3.4.24.-; Enamel metalloproteinase; Enamelysin; MMP-20", "protein_names_refseq": "MMP-20; enamel metalloproteinase; enamelysin; matrix metalloproteinase-20 precursor; matrix metalloproteinase-20; matrix metalloproteinase", "tax_id": 9823, "disease": "", "pathway": " (ssc:396939); (R-SSC-1442490); (R-SSC-1474228)", "pathway_count": 3, "publication_count": 4, "publication_id_list": "17046814;20400724;32543654;8996096", "class_list": "", "function": "Degrades amelogenin, the major protein component of the enamel matrix and two of the macromolecules characterizing the cartilage extracellular matrix: aggrecan and the cartilage oligomeric matrix protein (COMP). May play a central role in tooth enamel formation (By similarity)., [UniProtKB]; MMP-20 is the enzyme that processes ameloblastin during the secretory stage of amelogenesis, [RefSeq, PubMed]; MMP-20 processes dental sialophosphoprotein into smaller subunits in the dentin matrix during odontogenesis, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004222 metalloendopeptidase activity;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0031012 extracellular matrix", "go_biological_process": "GO:0006508 proteolysis;GO:0030198 extracellular matrix organization;GO:0030574 collagen catabolic process;GO:0097186 amelogenesis", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P79287-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q5PYH3-1", "uniprot_id": "SAR1B_PIG", "mass": 22382.0, "length": 198, "protein_name": "Small COPII coat GTPase SAR1B", "gene_name": "SAR1B", "organism": "Pig", "refseq_name": "small COPII coat GTPase SAR1B", "refseq_ac": "NP_001008689", "gene_names_uniprotkb": "SAR1B", "gene_names_refseq": "GTBPB; SAR1B; SARA2", "protein_names_uniprotkb": "Small COPII coat GTPase SAR1B; 3.6.5.2", "protein_names_refseq": "GTP-binding protein SAR1b; SAR1 gene homolog B; SAR1 homolog B; SAR1a gene homolog 2; small COPII coat GTPase SAR1B", "tax_id": 9823, "disease": "", "pathway": " (ssc:494017); (R-SSC-204005); (R-SSC-2132295); (R-SSC-5694530); (R-SSC-8963888); (R-SSC-983170)", "pathway_count": 6, "publication_count": 2, "publication_id_list": "16621763;32543654", "class_list": "", "function": "Small GTPase that cycles between an active GTP-bound and an inactive GDP-bound state and mainly functions in vesicle-mediated endoplasmic reticulum (ER) to Golgi transport. The active GTP-bound form inserts into the endoplasmic reticulum membrane where it recruits the remainder of the coat protein complex II/COPII. The coat protein complex II assembling and polymerizing on endoplasmic reticulum membrane is responsible for both the sorting of cargos and the deformation and budding of membranes into vesicles destined to the Golgi. In contrast to SAR1A, SAR1B specifically interacts with the cargo receptor SURF4 to mediate the transport of lipid-carrying lipoproteins including APOB and APOA1 from the endoplasmic reticulum to the Golgi and thereby, indirectly regulates lipid homeostasis. In addition to its role in vesicle trafficking, can also function as a leucine sensor regulating TORC1 signaling and more indirectly cellular metabolism, growth and survival. In absence of leucine, interacts with the GATOR2 complex via MIOS and inhibits TORC1 signaling. The binding of leucine abrogates the interaction with GATOR2 and the inhibition of the TORC1 signaling. This function is completely independent of the GTPase activity of SAR1B., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q4ZJK0", "ec_number_list": "", "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0046872 metal ion binding;GO:0003925 G protein activity;GO:0140785 amino acid sensor activity", "go_cellular_component": "GO:0005829 cytosol;GO:0005765 lysosomal membrane;GO:0005789 endoplasmic reticulum membrane;GO:0032580 Golgi cisterna membrane;GO:0070971 endoplasmic reticulum exit site", "go_biological_process": "GO:0032368 regulation of lipid transport;GO:0090110 COPII-coated vesicle cargo loading;GO:0006886 intracellular protein transport;GO:0042953 lipoprotein transport;GO:0055088 lipid homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q5PYH3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "O02858-1", "uniprot_id": "SCD_PIG", "mass": 41376.0, "length": 359, "protein_name": "Stearoyl-CoA desaturase", "gene_name": "SCD", "organism": "Pig", "refseq_name": "stearoyl-CoA desaturase", "refseq_ac": "NP_998946", "gene_names_uniprotkb": "SCD", "gene_names_refseq": "SCD", "protein_names_uniprotkb": "Stearoyl-CoA desaturase; 1.14.19.1; Acyl-CoA desaturase; Delta(9)-desaturase; Delta-9 desaturase; Fatty acid desaturase", "protein_names_refseq": "Acyl-CoA desaturase; delta(9)-desaturase; fatty acid desaturase; stearoyl-CoA desaturase 1; stearoyl-CoA desaturase", "tax_id": 9823, "disease": "", "pathway": " (ssc:396670)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "15147407;15556291;23881676;24465944;25875642;27240305;32244800;32543654", "class_list": "", "function": "Genetic association study in Duroc gilts/barrows in Spain: Data suggest that T allele in promoter region of SCD (2228T>C) leads to up-regulation of monounsaturated fatty acid content of biceps femoris/ham which is maintained in dry-cured ham., [RefSeq, PubMed]; Results indicated that the positive effect of the T allele at the SCD gene on monounsaturated fatty acid and of the T allele at the LEPR gene on saturated fatty acid are maintained throughout the growing-finishing period, both in longissimus thoracis and subcutaneous fat., [RefSeq, PubMed]; Stearoyl-CoA Desaturase is Essential for Porcine Adipocyte Differentiation. Publication Status: Online-Only, [RefSeq, PubMed]; Stearoyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates. Catalyzes the insertion of a cis double bond at the delta-9 position into fatty acyl-CoA substrates including palmitoyl-CoA and stearoyl-CoA (By similarity). Gives rise to a mixture of 16:1 and 18:1 unsaturated fatty acids. Plays an important role in lipid biosynthesis. Plays an important role in regulating the expression of genes that are involved in lipogenesis and in regulating mitochondrial fatty acid oxidation (By similarity). Plays an important role in body energy homeostasis (By similarity). Contributes to the biosynthesis of membrane phospholipids, cholesterol esters and triglycerides (By similarity)., [UniProtKB, UniProtKB]; Stearoyl-CoA desaturase(SCD) has a total of 21 gene polymorphisms in the 21-kb DNA sequence, adn RT-PCR result indicates that the SCD gene is expressed ubiquitously in tissues., [RefSeq, PubMed]; The study provides evidence that there exists genetic variation in the SCD gene with the potential to increase monounsaturated content in pork. Publication Status: Online-Only, [RefSeq, PubMed]; There was a positive relationship between stearoyl-CoA desaturase (SCD) protein expression in longissimus muscle and monounsaturated fatty acid content, and SCD protein expression and total muscle fatty acid content in Large White x Landrace breeds., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A4X1U207;Q6RWA7", "ec_number_list": "", "go_molecular_function": "GO:0005506 iron ion binding;GO:0004768 stearoyl-CoA 9-desaturase activity;GO:0016491 oxidoreductase activity;GO:0032896 palmitoyl-CoA 9-desaturase activity", "go_cellular_component": "GO:0016020 membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006636 unsaturated fatty acid biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "O02858-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P67985-1", "uniprot_id": "RL22_PIG", "mass": 14759.0, "length": 128, "protein_name": "Large ribosomal subunit protein eL22", "gene_name": "RPL22", "organism": "Pig", "refseq_name": "large ribosomal subunit protein eL22", "refseq_ac": "NP_999152", "gene_names_uniprotkb": "RPL22", "gene_names_refseq": "HBP15/L22; RPL22", "protein_names_uniprotkb": "Large ribosomal subunit protein eL22; 60S ribosomal protein L22; Heparin-binding protein HBp15", "protein_names_refseq": "60S ribosomal protein L22; heparin binding protein; heparin-binding protein HBp15; large ribosomal subunit protein eL22", "tax_id": 9823, "disease": "", "pathway": " (ssc:397047); (R-SSC-156827); (R-SSC-1799339); (R-SSC-6791226); (R-SSC-72689); (R-SSC-72706); (R-SSC-975956); (R-SSC-975957); (R-SSC-9954709); (R-SSC-9954714); (R-SSC-9954716)", "pathway_count": 11, "publication_count": 2, "publication_id_list": "32543654;8135813", "class_list": "", "function": "Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "P41104", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding;GO:0008201 heparin binding;GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0098793 presynapse;GO:0098556 cytoplasmic side of rough endoplasmic reticulum membrane;GO:0022625 cytosolic large ribosomal subunit;GO:0015934 large ribosomal subunit", "go_biological_process": "GO:0002181 cytoplasmic translation;GO:0140236 translation at presynapse;GO:0006412 translation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "P67985-1", "record_type": "protein" }, { "uniprot_canonical_ac": "I3L897-1", "uniprot_id": "I3L897_PIG", "mass": 61505.0, "length": 536, "protein_name": "SNW domain-containing protein 1", "gene_name": "SNW1", "organism": "Pig", "refseq_name": "SNW domain-containing protein 1", "refseq_ac": "XP_020955214", "gene_names_uniprotkb": "SNW1", "gene_names_refseq": "SNW1", "protein_names_uniprotkb": "SNW domain-containing protein 1", "protein_names_refseq": "SNW domain-containing protein 1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100623576); (R-SSC-2173795); (R-SSC-350054); (R-SSC-72163); (R-SSC-8941856)", "pathway_count": 5, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Involved in pre-mRNA splicing., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A4X1T4R9", "ec_number_list": "", "go_molecular_function": "GO:0003713 transcription coactivator activity;GO:0019899 enzyme binding;GO:0003714 transcription corepressor activity;GO:0005112 Notch binding;GO:0046332 SMAD binding", "go_cellular_component": "GO:0005681 spliceosomal complex;GO:0016607 nuclear speck;GO:0016363 nuclear matrix;GO:0071007 U2-type catalytic step 2 spliceosome;GO:0008024 cyclin/CDK positive transcription elongation factor complex", "go_biological_process": "GO:0000398 mRNA splicing, via spliceosome;GO:0048026 positive regulation of mRNA splicing, via spliceosome;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0071300 cellular response to retinoic acid", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "I3L897-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P02632-1", "uniprot_id": "S100G_PIG", "mass": 8929.0, "length": 79, "protein_name": "Protein S100-G", "gene_name": "S100G", "organism": "Pig", "refseq_name": "protein S100-G", "refseq_ac": "NP_999305", "gene_names_uniprotkb": "S100G; CALB3; S100D", "gene_names_refseq": "CALB3; S100G", "protein_names_uniprotkb": "Protein S100-G; CABP; Calbindin-D9k; S100 calcium-binding protein G; Vitamin D-dependent calcium-binding protein, intestinal", "protein_names_refseq": "CABP; calbindin D-9k; calbindin-D9k; protein S100-G; vitamin D-dependent calcium-binding protein, intestinal", "tax_id": 9823, "disease": "", "pathway": " (ssc:397265)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "1391336;1734952;19641180;2775745;32543654;476518", "class_list": "", "function": "S100G expression in endometrium showed a biphasic pattern of increases on D12 of pregnancy and from D60 to term, and it localized to luminal epithelial cells during early pregnancy and to luminal and glandular cells and chorionic membrane from D30 to term, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0046914 transition metal ion binding;GO:0048306 calcium-dependent protein binding;GO:0005509 calcium ion binding;GO:0005499 vitamin D binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0016323 basolateral plasma membrane;GO:0016324 apical plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P02632-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1S1C3-1", "uniprot_id": "F1S1C3_PIG", "mass": 35256.0, "length": 311, "protein_name": "Carbonic anhydrase 4", "gene_name": "CA4", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "CA4", "gene_names_refseq": "", "protein_names_uniprotkb": "Carbonic anhydrase 4; 4.2.1.1; Carbonate dehydratase IV; Carbonic anhydrase IV", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-1237044); (R-SSC-1247673); (R-SSC-1475029)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Catalyzes the reversible hydration of carbon dioxide into bicarbonate and protons and thus is essential to maintaining intracellular and extracellular pH. May stimulate the sodium/bicarbonate transporter activity of SLC4A4 that acts in pH homeostasis. It is essential for acid overload removal from the retina and retina epithelium, and acid release in the choriocapillaris in the choroid., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0004089 carbonate dehydratase activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0098552 side of membrane;GO:0005791 rough endoplasmic reticulum;GO:0048471 perinuclear region of cytoplasm;GO:0070062 extracellular exosome", "go_biological_process": "GO:0015701 bicarbonate transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1S1C3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1S3D6-1", "uniprot_id": "F1S3D6_PIG", "mass": 61451.0, "length": 567, "protein_name": "Regulator of G-protein signaling 14", "gene_name": "RGS14", "organism": "Pig", "refseq_name": "regulator of G-protein signaling 14 isoform X1", "refseq_ac": "XP_005661509", "gene_names_uniprotkb": "RGS14", "gene_names_refseq": "RGS14", "protein_names_uniprotkb": "Regulator of G-protein signaling 14", "protein_names_refseq": "regulator of G-protein signaling 14 isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100524790); (R-SSC-418594)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005096 GTPase activator activity;GO:0008017 microtubule binding;GO:0001965 G-protein alpha-subunit binding;GO:0032794 GTPase activating protein binding;GO:0005092 GDP-dissociation inhibitor activity", "go_cellular_component": "GO:0000922 spindle pole;GO:0005813 centrosome;GO:0005874 microtubule;GO:0005886 plasma membrane;GO:0014069 postsynaptic density", "go_biological_process": "GO:0007165 signal transduction;GO:0051301 cell division;GO:0009968 negative regulation of signal transduction;GO:0006913 nucleocytoplasmic transport;GO:0007059 chromosome segregation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1S3D6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "I3LUZ9-1", "uniprot_id": "I3LUZ9_PIG", "mass": 44730.0, "length": 443, "protein_name": "Transcription factor GATA-4", "gene_name": "GATA4", "organism": "Pig", "refseq_name": "transcription factor GATA-4 isoform X1", "refseq_ac": "XP_005657325", "gene_names_uniprotkb": "GATA4", "gene_names_refseq": "GATA4", "protein_names_uniprotkb": "Transcription factor GATA-4; GATA-binding factor 4", "protein_names_refseq": "transcription factor GATA-4 isoform X1", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-983231)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0008270 zinc ion binding;GO:0043565 sequence-specific DNA binding;GO:0070410 co-SMAD binding;GO:0000976 transcription cis-regulatory region binding", "go_cellular_component": "GO:0005634 nucleus;GO:0016604 nuclear body;GO:0090575 RNA polymerase II transcription regulator complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0003290 atrial septum secundum morphogenesis;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0045944 positive regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "I3LUZ9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1RV14-1", "uniprot_id": "F1RV14_PIG", "mass": 76403.0, "length": 669, "protein_name": "Protein kinase C", "gene_name": "PRKCA", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "PRKCA", "gene_names_refseq": "", "protein_names_uniprotkb": "Protein kinase C; 2.7.11.13", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-111933); (R-SSC-114516); (R-SSC-1250196); (R-SSC-1433557); (R-SSC-1433559); (R-SSC-2179392); (R-SSC-3000170); (R-SSC-399997); (R-SSC-416993); (R-SSC-4419969); (R-SSC-450520); (R-SSC-5099900); (R-SSC-5218921); (R-SSC-5668599); (R-SSC-76005); (R-SSC-8853659)", "pathway_count": 16, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0008270 zinc ion binding;GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0019899 enzyme binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0005783 endoplasmic reticulum;GO:0005829 cytosol", "go_biological_process": "GO:0006915 apoptotic process;GO:0009967 positive regulation of signal transduction;GO:0035556 intracellular signal transduction;GO:0045785 positive regulation of cell adhesion;GO:0045931 positive regulation of mitotic cell cycle", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1RV14-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1RYC5-1", "uniprot_id": "F1RYC5_PIG", "mass": 52637.0, "length": 457, "protein_name": "Glycine receptor alpha 4 (pseudo", "gene_name": "GLRA2", "organism": "Pig", "refseq_name": "glycine receptor subunit alpha-4", "refseq_ac": "XP_003135319", "gene_names_uniprotkb": "GLRA2", "gene_names_refseq": "GLRA4", "protein_names_uniprotkb": "Glycine receptor alpha 4 (pseudo", "protein_names_refseq": "glycine receptor subunit alpha-4", "tax_id": 9823, "disease": "", "pathway": " (ssc:100525376)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0022824 transmitter-gated monoatomic ion channel activity;GO:0004888 transmembrane signaling receptor activity;GO:0005254 chloride channel activity;GO:0016594 glycine binding;GO:0016934 extracellularly glycine-gated chloride channel activity", "go_cellular_component": "GO:0045211 postsynaptic membrane;GO:0034707 chloride channel complex;GO:0042995 cell projection;GO:0098690 glycinergic synapse;GO:0099634 postsynaptic specialization membrane", "go_biological_process": "GO:1902476 chloride transmembrane transport;GO:0043200 response to amino acid", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1RYC5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P49921-1", "uniprot_id": "GON1_PIG", "mass": 10090.0, "length": 91, "protein_name": "Progonadoliberin-1", "gene_name": "GNRH1", "organism": "Pig", "refseq_name": "progonadoliberin-1 precursor", "refseq_ac": "NP_999439", "gene_names_uniprotkb": "GNRH1; GNRH", "gene_names_refseq": "GNRH1; LHRH", "protein_names_uniprotkb": "Progonadoliberin-1; GnRH-I; GnRH-associated peptide I; Gonadoliberin I; Gonadotropin-releasing hormone I; LH-RH I; Luliberin I; Luteinizing hormone-releasing hormone I; Progonadoliberin I", "protein_names_refseq": "gonadotropin-releasing hormone associated peptide; luteinizing hormone-releasing hormone; progonadoliberin I; progonadoliberin-1 precursor; progonadoliberin-1", "tax_id": 9823, "disease": "", "pathway": " (ssc:397516); (R-SSC-375281); (R-SSC-416476)", "pathway_count": 3, "publication_count": 4, "publication_id_list": "32543654;4942726;4946067;4946275", "class_list": "", "function": "Stimulates the secretion of gonadotropins; it stimulates the secretion of both luteinizing and follicle-stimulating hormones., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005183 gonadotropin hormone-releasing hormone activity;GO:0031530 gonadotropin-releasing hormone receptor binding", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0023051 regulation of signaling", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P49921-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SDB7-1", "uniprot_id": "F1SDB7_PIG", "mass": 56070.0, "length": 495, "protein_name": "Flavin-containing monooxygenase 5", "gene_name": "FMO5", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "FMO5", "gene_names_refseq": "", "protein_names_uniprotkb": "Flavin-containing monooxygenase 5; 1.14.13.8; 1.6.3.1", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Acts as Baeyer-Villiger monooxygenase on a broad range of substrates. Catalyzes the insertion of an oxygen atom into a carbon-carbon bond adjacent to a carbonyl, which converts ketones to esters., [UniProtKB, UniProtKB]; Acts as a Baeyer-Villiger monooxygenase on a broad range of substrates. Catalyzes the insertion of an oxygen atom into a carbon-carbon bond adjacent to a carbonyl, which converts ketones to esters. Active on diverse carbonyl compounds, whereas soft nucleophiles are mostly non- or poorly reactive. In contrast with other forms of FMO it is non- or poorly active on 'classical' substrates such as drugs, pesticides, and dietary components containing soft nucleophilic heteroatoms. Able to oxidize drug molecules bearing a carbonyl group on an aliphatic chain, such as nabumetone and pentoxifylline. Also, in the absence of substrates, shows slow but yet significant NADPH oxidase activity. Acts as a positive modulator of cholesterol biosynthesis as well as glucose homeostasis, promoting metabolic aging via pleiotropic effects., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Broad spectrum monooxygenase that catalyzes the oxygenation of a wide variety of nitrogen- and sulfur-containing compounds including xenobiotics. Catalyzes the S-oxygenation of hypotaurine to produce taurine, an organic osmolyte involved in cell volume regulation as well as a variety of cytoprotective and developmental processes. In vitro, catalyzes the N-oxygenation of trimethylamine (TMA) to produce trimethylamine N-oxide (TMAO) and could therefore participate to the detoxification of this compound that is generated by the action of gut microbiota from dietary precursors such as choline, choline containing compounds, betaine or L-carnitine., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0050660 flavin adenine dinucleotide binding;GO:0016174 NAD(P)H oxidase H2O2-forming activity;GO:0034899 trimethylamine monooxygenase activity;GO:0050661 NADP binding;GO:0004499 N,N-dimethylaniline monooxygenase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006629 lipid metabolic process;GO:0090181 regulation of cholesterol metabolic process;GO:0006805 xenobiotic metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SDB7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F6PWN2-1", "uniprot_id": "F6PWN2_PIG", "mass": 20592.0, "length": 182, "protein_name": "Receptor activity-modifying protein 2", "gene_name": "RAMP2", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "RAMP2", "gene_names_refseq": "", "protein_names_uniprotkb": "Receptor activity-modifying protein 2", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-419812); (R-SSC-9856530)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Accessory protein that interacts with and modulates the function of G-protein coupled receptors including calcitonin gene-related peptide type 1 receptor (CALCRL) and calcitonin receptor (CALCR). Required for the transport of CALCRL to the plasma membrane. Together with CALCRL, form a receptor complex for adrenomedullin/ADM. Together with CALCR, act as a receptor complex for calcitonin/CT/CALC. Together with CALCR, also act as a receptor complex for amylin/IAPP., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0015026 coreceptor activity;GO:0001605 adrenomedullin receptor activity;GO:1990409 adrenomedullin binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0009986 cell surface;GO:0043235 receptor complex;GO:1903143 adrenomedullin receptor complex", "go_biological_process": "GO:0001525 angiogenesis;GO:0001570 vasculogenesis;GO:0006886 intracellular protein transport;GO:0007186 G protein-coupled receptor signaling pathway;GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F6PWN2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "I3LV70-1", "uniprot_id": "I3LV70_PIG", "mass": 94794.0, "length": 846, "protein_name": "Cystic fibrosis transmembrane conductance regulator", "gene_name": "LOC106505329", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "LOC106505329", "gene_names_refseq": "", "protein_names_uniprotkb": "Cystic fibrosis transmembrane conductance regulator; 5.6.1.6; ATP-binding cassette sub-family C member 7; Channel conductance-controlling ATPase; cAMP-dependent chloride channel", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005260 intracellularly ATP-gated chloride channel activity;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0140359 ABC-type transporter activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane;GO:0016324 apical plasma membrane;GO:0031901 early endosome membrane;GO:0055038 recycling endosome membrane;GO:0034707 chloride channel complex", "go_biological_process": "GO:0055085 transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "I3LV70-1", "record_type": "protein" }, { "uniprot_canonical_ac": "K7GKX0-1", "uniprot_id": "K7GKX0_PIG", "mass": 132671.0, "length": 1236, "protein_name": "Delta-like protein", "gene_name": "JAG2", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "JAG2", "gene_names_refseq": "", "protein_names_uniprotkb": "Delta-like protein", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Putative Notch ligand involved in the mediation of Notch signaling., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005509 calcium ion binding;GO:0005112 Notch binding;GO:0008083 growth factor activity", "go_cellular_component": "GO:0016020 membrane;GO:0005886 plasma membrane", "go_biological_process": "GO:0007219 Notch signaling pathway;GO:0007283 spermatogenesis;GO:0045061 thymic T cell selection;GO:0042127 regulation of cell population proliferation;GO:0045747 positive regulation of Notch signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "K7GKX0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P79382-1", "uniprot_id": "MGST1_PIG", "mass": 17650.0, "length": 155, "protein_name": "Microsomal glutathione S-transferase 1", "gene_name": "MGST1", "organism": "Pig", "refseq_name": "microsomal glutathione S-transferase 1", "refseq_ac": "NP_999465", "gene_names_uniprotkb": "MGST1; GST12", "gene_names_refseq": "MGST1", "protein_names_uniprotkb": "Microsomal glutathione S-transferase 1; 2.5.1.18; Microsomal GST-1; Microsomal GST-I", "protein_names_refseq": "glutathione S-transferase; microsomal GST-1; microsomal GST-I; microsomal glutathione S-transferase 1", "tax_id": 9823, "disease": "", "pathway": " (ssc:397567); (R-SSC-156590); (R-SSC-5423646); (R-SSC-6798695)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004364 glutathione transferase activity;GO:0004602 glutathione peroxidase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005741 mitochondrial outer membrane;GO:0005783 endoplasmic reticulum;GO:0016020 membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0034635 glutathione transport;GO:0071449 cellular response to lipid hydroperoxide", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "P79382-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SP99-1", "uniprot_id": "F1SP99_PIG", "mass": 44261.0, "length": 400, "protein_name": "D(3) dopamine receptor", "gene_name": "DRD3", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "DRD3", "gene_names_refseq": "", "protein_names_uniprotkb": "D(3) dopamine receptor; Dopamine D3 receptor", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-390651); (R-SSC-418594)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Dopamine receptor that is primarily expressed in limbic areas of the brain and is involved in the modulation of cognitive, emotional, and endocrine functions. Plays a key role in regulating neuronal signaling pathways associated with motivation, reward, and behavior. Coupled to G(i)/G(o) proteins; activation leads to inhibition of adenylate cyclase and decreased intracellular cAMP levels. Involved in the control of locomotor activity and implicated in several neuropsychiatric disorders, including schizophrenia and substance use disorders. Promotes cell proliferation through MAP kinase signaling. Also involved in autophagy regulation: receptor activation stimulates AMPK, which phosphorylates RPTOR and enhances its interaction with MTOR, thereby inhibiting MTORC1 signaling and its downstream target RPS6KB1. This leads to activation of ULK1 and initiation of the autophagy cascade. Forms heterotetramers with DRD1 to potentiate beta-arrestin recruitment and mediate locomotor activity., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go;GO:0004930 G protein-coupled receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0045202 synapse", "go_biological_process": "GO:0045744 negative regulation of G protein-coupled receptor signaling pathway;GO:0048148 behavioral response to cocaine;GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway;GO:1903530 regulation of secretion by cell;GO:0051952 regulation of amine transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SP99-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1S2L2-1", "uniprot_id": "F1S2L2_PIG", "mass": 59991.0, "length": 542, "protein_name": "Telomeric repeat-binding factor 2", "gene_name": "TERF2", "organism": "Pig", "refseq_name": "telomeric repeat-binding factor 2", "refseq_ac": "XP_003126956", "gene_names_uniprotkb": "TERF2", "gene_names_refseq": "TERF2", "protein_names_uniprotkb": "Telomeric repeat-binding factor 2; TTAGGG repeat-binding factor 2; Telomeric DNA-binding protein", "protein_names_refseq": "telomeric repeat-binding factor 2", "tax_id": 9823, "disease": "", "pathway": " (ssc:100517762); (R-SSC-110330); (R-SSC-110331); (R-SSC-171306); (R-SSC-171319); (R-SSC-174411); (R-SSC-174414); (R-SSC-174417); (R-SSC-174430); (R-SSC-174437); (R-SSC-2559586); (R-SSC-9670095)", "pathway_count": 12, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Binds the telomeric double-stranded 5'-TTAGGG-3' repeat., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0042803 protein homodimerization activity;GO:0044877 protein-containing complex binding;GO:0003691 double-stranded telomeric DNA binding;GO:0098505 G-rich strand telomeric DNA binding;GO:0019899 enzyme binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0000782 telomere cap complex;GO:0016604 nuclear body;GO:0070187 shelterin complex;GO:0001673 male germ cell nucleus", "go_biological_process": "GO:0031848 protection from non-homologous end joining at telomere;GO:0032206 positive regulation of telomere maintenance;GO:0031627 telomeric loop formation;GO:0032208 negative regulation of telomere maintenance via recombination;GO:1904430 negative regulation of t-circle formation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1S2L2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1RRV7-1", "uniprot_id": "F1RRV7_PIG", "mass": 39714.0, "length": 343, "protein_name": "CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1", "gene_name": "ST3GAL1", "organism": "Pig", "refseq_name": "CMP-N-acetylneuraminate-beta-galactosamide- alpha-2,3-sialyltransferase 1 isoform X1", "refseq_ac": "XP_005662893", "gene_names_uniprotkb": "ST3GAL1", "gene_names_refseq": "SIAT4A; ST3GAL1", "protein_names_uniprotkb": "CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1; 2.4.3.2; 2.4.3.4; Gal-NAc6S; Gal-beta-1,3-GalNAc-alpha-2,3-sialyltransferase; Monosialoganglioside sialyltransferase; ST3Gal I; ST3GalA.1; ST3O; Sialyltransferase 4A", "protein_names_refseq": "CMP-N-acetylneuraminate-beta-galactosamide- alpha-2,3-sialyltransferase 1 isoform X1", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-2022854); (R-SSC-4085001); (R-SSC-977068)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "K7GPR8", "ec_number_list": "", "go_molecular_function": "GO:0047288 beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminide alpha-2,3- sialyltransferase;GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0016020 membrane;GO:0032588 trans-Golgi network membrane;GO:1990675 Golgi medial cisterna membrane;GO:1990676 Golgi trans cisterna membrane", "go_biological_process": "GO:0009101 glycoprotein biosynthetic process;GO:1905403 negative regulation of activated CD8-positive, alpha-beta T cell apoptotic process;GO:0097503 sialylation;GO:0001574 ganglioside biosynthetic process;GO:0002319 memory B cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1RRV7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1RS43-1", "uniprot_id": "F1RS43_PIG", "mass": 48960.0, "length": 460, "protein_name": "3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial", "gene_name": "OXSM", "organism": "Pig", "refseq_name": "3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial", "refseq_ac": "XP_020927098", "gene_names_uniprotkb": "OXSM", "gene_names_refseq": "OXSM", "protein_names_uniprotkb": "3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial; 2.3.1.41", "protein_names_refseq": "3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial", "tax_id": 9823, "disease": "", "pathway": " (ssc:102162360); (R-SSC-9837999)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "May play a role in the biosynthesis of lipoic acid as well as longer chain fatty acids required for optimal mitochondrial function., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, 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"GO:0005739 mitochondrion", "go_biological_process": "GO:0006637 acyl-CoA metabolic process;GO:0051792 medium-chain fatty acid biosynthetic process;GO:0051790 short-chain fatty acid biosynthetic process;GO:0006633 fatty acid biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1RS43-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1RSJ8-1", "uniprot_id": "F1RSJ8_PIG", "mass": 94762.0, "length": 836, "protein_name": "pre-rRNA processing protein FTSJ3", "gene_name": "FTSJ3", "organism": "Pig", "refseq_name": "pre-rRNA processing protein FTSJ3", "refseq_ac": "XP_013836304", "gene_names_uniprotkb": "FTSJ3", "gene_names_refseq": "FTSJ3", "protein_names_uniprotkb": "pre-rRNA processing protein FTSJ3; 2'-O-ribose RNA methyltransferase SPB1 homolog; 2.1.1.-; Protein ftsJ homolog 3; Putative rRNA methyltransferase 3", "protein_names_refseq": "pre-rRNA processing protein FTSJ3", "tax_id": 9823, "disease": "", "pathway": " (ssc:100512190)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Probable methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "F1RSJ9", "ec_number_list": "", "go_molecular_function": "GO:0016435 rRNA (guanine) methyltransferase activity;GO:0008650 rRNA (uridine-2'-O-)-methyltransferase activity", "go_cellular_component": "GO:0005730 nucleolus;GO:0030687 preribosome, large subunit precursor;GO:0030688 preribosome, small subunit precursor", "go_biological_process": "GO:0031167 rRNA methylation;GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA);GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1RSJ8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1RSU9-1", "uniprot_id": "F1RSU9_PIG", "mass": 33013.0, "length": 310, "protein_name": "Caudal type homeobox 2", "gene_name": "CDX2", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "CDX2", "gene_names_refseq": "", "protein_names_uniprotkb": "Caudal type homeobox 2", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0008327 methyl-CpG binding", "go_cellular_component": "GO:0000794 condensed nuclear chromosome;GO:0005634 nucleus;GO:0017053 transcription repressor complex", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0030154 cell differentiation;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0048565 digestive tract development;GO:0009948 anterior/posterior axis specification", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1RSU9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1RSV0-1", "uniprot_id": "F1RSV0_PIG", "mass": 23019.0, "length": 211, "protein_name": "2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase", "gene_name": "URAD", "organism": "Pig", "refseq_name": "putative 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase", "refseq_ac": "XP_003357857", "gene_names_uniprotkb": "URAD", "gene_names_refseq": "URAD", "protein_names_uniprotkb": "2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase; 4.1.1.97; Parahox neighbor; Ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5-) decarboxylase", "protein_names_refseq": "putative 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase", "tax_id": 9823, "disease": "", "pathway": " (ssc:100515273)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Catalyzes the stereoselective decarboxylation of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU) to (S)-allantoin., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0051997 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase activity", "go_cellular_component": "GO:0005777 peroxisome", "go_biological_process": "GO:0019628 urate catabolic process;GO:0006144 purine nucleobase metabolic process;GO:0000255 allantoin metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1RSV0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1RT62-1", "uniprot_id": "F1RT62_PIG", "mass": 112763.0, "length": 1011, "protein_name": "Integrin alpha-3", "gene_name": "ITGA3", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "ITGA3", "gene_names_refseq": "", "protein_names_uniprotkb": "Integrin alpha-3; CD49 antigen-like family member C; Galactoprotein B3; VLA-3 subunit alpha", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-216083); (R-SSC-3000157)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Integrin alpha-3/beta-1 is a receptor for fibronectin, laminin, collagen, epiligrin, thrombospondin and CSPG4. Integrin alpha-3/beta-1 provides a docking site for FAP (seprase) at invadopodia plasma membranes in a collagen-dependent manner and hence may participate in the adhesion, formation of invadopodia and matrix degradation processes, promoting cell invasion. Alpha-3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "K7GNL6", "ec_number_list": "", "go_molecular_function": "GO:0002020 protease binding;GO:0046982 protein heterodimerization activity;GO:0038023 signaling receptor activity", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0048787 presynaptic active zone membrane;GO:0009986 cell surface;GO:0016323 basolateral plasma membrane;GO:0031594 neuromuscular junction", "go_biological_process": "GO:0017015 regulation of transforming growth factor beta receptor signaling pathway;GO:0072006 nephron development;GO:0007229 integrin-mediated signaling pathway;GO:0030324 lung development;GO:0098609 cell-cell adhesion", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1RT62-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1RUG5-1", "uniprot_id": "F1RUG5_PIG", "mass": 182815.0, "length": 1655, "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "WNK3", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "WNK3", "gene_names_refseq": "", "protein_names_uniprotkb": "non-specific serine/threonine protein kinase; 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1-phosphatidylinositol 5-phosphate 4-kinase 2-alpha; 2.7.1.149; Diphosphoinositide kinase 2-alpha; Phosphatidylinositol 5-phosphate 4-kinase type II alpha; PtdIns(5)P-4-kinase isoform 2-alpha", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (ssc:100520446); (R-SSC-1660499); (R-SSC-6811555); (R-SSC-6811558); (R-SSC-8847453)", "pathway_count": 5, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity;GO:0005524 ATP binding;GO:0042803 protein homodimerization activity;GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0005764 lysosome;GO:0005776 autophagosome", "go_biological_process": "GO:0046627 negative regulation of insulin receptor signaling pathway;GO:0035855 megakaryocyte development;GO:2000786 positive regulation of autophagosome assembly;GO:0046854 phosphatidylinositol phosphate biosynthetic process;GO:0090119 vesicle-mediated cholesterol transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1RVI6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1RW73-1", "uniprot_id": "F1RW73_PIG", "mass": 55590.0, "length": 505, "protein_name": "Bone morphogenetic protein 6", "gene_name": "BMP6", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "BMP6", "gene_names_refseq": "", "protein_names_uniprotkb": "Bone morphogenetic protein 6", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0046982 protein heterodimerization activity;GO:0005125 cytokine activity;GO:0008083 growth factor activity;GO:0070700 BMP receptor binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0032991 protein-containing complex", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006954 inflammatory response;GO:0006955 immune response;GO:0007507 heart development;GO:0010628 positive regulation of gene expression", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1RW73-1", "record_type": "protein" }, { "uniprot_canonical_ac": "I3L709-1", "uniprot_id": "I3L709_PIG", "mass": 36852.0, "length": 318, "protein_name": "Polyprenal reductase", "gene_name": "", "organism": "Pig", "refseq_name": "polyprenol reductase isoform X1", "refseq_ac": "XP_003129036", "gene_names_uniprotkb": "", "gene_names_refseq": "LOC100525350", "protein_names_uniprotkb": "Polyprenal reductase; 1.3.1.22; 1.3.1.94", "protein_names_refseq": "polyprenol reductase isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100525350); (R-SSC-193048); (R-SSC-446199)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Plays a key role in early steps of protein N-linked glycosylation by being involved in the conversion of polyprenol into dolichol. Acts as a polyprenal reductase that mediates the reduction of polyprenal into dolichal in a NADP-dependent mechanism. Dolichols are required for the synthesis of dolichol-linked monosaccharides and the oligosaccharide precursor used for N-glycosylation. Also able to convert testosterone (T) into 5-alpha-dihydrotestosterone (DHT)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, 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Has highest activity on alpha-1,4-linked glycosidic linkages, but can also hydrolyze alpha-1,6-linked glucans., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004558 alpha-1,4-glucosidase activity;GO:0030246 carbohydrate binding;GO:0043896 glucan 1,6-alpha-glucosidase activity", "go_cellular_component": "GO:0005765 lysosomal membrane;GO:0120282 autolysosome lumen", "go_biological_process": "GO:0007040 lysosome organization;GO:0061723 glycophagy;GO:0002086 diaphragm contraction;GO:0005980 glycogen catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1RZ82-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1RZG3-1", "uniprot_id": "F1RZG3_PIG", "mass": 46297.0, "length": 410, "protein_name": "Homeobox protein Hox-D10", "gene_name": "HOXD10", "organism": "Pig", "refseq_name": "homeobox protein Hox-D10", "refseq_ac": "XP_020932004", "gene_names_uniprotkb": "HOXD10", "gene_names_refseq": "HOXD10", "protein_names_uniprotkb": "Homeobox protein Hox-D10", "protein_names_refseq": "homeobox protein Hox-D10", "tax_id": 9823, "disease": "", "pathway": " (ssc:100517431)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A4X1UIY7", "ec_number_list": "", "go_molecular_function": "GO:0003682 chromatin binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1RZG3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1RZU1-1", "uniprot_id": "F1RZU1_PIG", "mass": 74346.0, "length": 691, "protein_name": "Interleukin-1 receptor-associated kinase 1", "gene_name": "IRAK1", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "IRAK1", "gene_names_refseq": "", "protein_names_uniprotkb": "Interleukin-1 receptor-associated kinase 1; 2.7.11.1", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-1257604); (R-SSC-209543); (R-SSC-209560); (R-SSC-445989); (R-SSC-450302); (R-SSC-450321); (R-SSC-6811558); (R-SSC-9020702); (R-SSC-937039); (R-SSC-975144)", "pathway_count": 10, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0019901 protein kinase binding;GO:0042803 protein homodimerization activity;GO:0046982 protein heterodimerization activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005811 lipid droplet;GO:0005829 cytosol", "go_biological_process": "GO:0070498 interleukin-1-mediated signaling pathway;GO:1904996 positive regulation of leukocyte adhesion to vascular endothelial cell;GO:0035556 intracellular signal transduction;GO:0045087 innate immune response;GO:0006355 regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1RZU1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1RZY6-1", "uniprot_id": "F1RZY6_PIG", "mass": 23486.0, "length": 201, "protein_name": "Charged multivesicular body protein 6", "gene_name": "CHMP6", "organism": "Pig", "refseq_name": "charged multivesicular body protein 6", "refseq_ac": "XP_020922158", "gene_names_uniprotkb": "CHMP6", "gene_names_refseq": "CHMP6", "protein_names_uniprotkb": "Charged multivesicular body protein 6", "protein_names_refseq": "charged multivesicular body protein 6", "tax_id": 9823, "disease": "", "pathway": " (ssc:100512857); (R-SSC-1632852); (R-SSC-5620971); (R-SSC-917729); (R-SSC-9668328)", "pathway_count": 5, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0044877 protein-containing complex binding", "go_cellular_component": "GO:0000815 ESCRT III complex;GO:0005828 kinetochore microtubule;GO:0005635 nuclear envelope;GO:0005886 plasma membrane;GO:0005765 lysosomal membrane", "go_biological_process": "GO:0001778 plasma membrane repair;GO:0031468 nuclear membrane reassembly;GO:0039702 viral budding via host ESCRT complex;GO:0097352 autophagosome maturation;GO:0015031 protein transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1RZY6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1S024-1", "uniprot_id": "F1S024_PIG", "mass": 68043.0, "length": 614, "protein_name": "Transporter", "gene_name": "SLC6A3", "organism": "Pig", "refseq_name": "sodium-dependent dopamine transporter", "refseq_ac": "XP_020932498", "gene_names_uniprotkb": "SLC6A3", "gene_names_refseq": "SLC6A3", "protein_names_uniprotkb": "Transporter", "protein_names_refseq": "sodium-dependent dopamine transporter", "tax_id": 9823, "disease": "", "pathway": " (ssc:100521346); (R-SSC-379397); (R-SSC-379398); (R-SSC-379401); (R-SSC-442660)", "pathway_count": 5, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Mediates sodium- and chloride-dependent transport of dopamine. Also mediates sodium- and chloride-dependent transport of norepinephrine (also known as noradrenaline). Regulator of light-dependent retinal hyaloid vessel regression, downstream of OPN5 signaling., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005326 neurotransmitter transmembrane transporter activity;GO:0046872 metal ion binding;GO:0005330 dopamine:sodium symporter activity;GO:0035240 dopamine binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0009986 cell surface;GO:0043025 neuronal cell body;GO:0043679 axon terminus;GO:0016600 flotillin complex", "go_biological_process": "GO:1990384 hyaloid vascular plexus regression;GO:0006865 amino acid transport;GO:0035725 sodium ion transmembrane transport;GO:0001504 neurotransmitter uptake", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1S024-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1S0B3-1", "uniprot_id": "F1S0B3_PIG", "mass": 69979.0, "length": 643, "protein_name": "ATP-dependent DNA helicase PIF1", "gene_name": "PIF1", "organism": "Pig", "refseq_name": "ATP-dependent DNA helicase PIF1 isoform X6", "refseq_ac": "XP_020949425", "gene_names_uniprotkb": "PIF1", "gene_names_refseq": "PIF1", "protein_names_uniprotkb": "ATP-dependent DNA helicase PIF1; 5.6.2.3; DNA 5'-3' helicase PIF1; DNA repair and recombination helicase PIF1", "protein_names_refseq": "ATP-dependent DNA helicase PIF1 isoform X6", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-171319)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA ends. Releases telomerase by unwinding the short telomerase RNA/telomeric DNA hybrid that is the intermediate in the telomerase reaction. Possesses an intrinsic strand annealing activity., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0042162 telomeric DNA binding;GO:0051880 G-quadruplex DNA binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005739 mitochondrion;GO:0000781 chromosome, telomeric region", "go_biological_process": "GO:0006281 DNA repair;GO:0006310 DNA recombination;GO:0000723 telomere maintenance;GO:0032211 negative regulation of telomere maintenance via telomerase;GO:0001117 protein-DNA-RNA complex disassembly", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1S0B3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1S0E6-1", "uniprot_id": "F1S0E6_PIG", "mass": 52808.0, "length": 472, "protein_name": "Cannabinoid receptor 1", "gene_name": "CNR1", "organism": "Pig", "refseq_name": "cannabinoid receptor 1", "refseq_ac": "XP_005659345", "gene_names_uniprotkb": "CNR1", "gene_names_refseq": "CNR1", "protein_names_uniprotkb": "Cannabinoid receptor 1", "protein_names_refseq": "cannabinoid receptor 1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100520160); (R-SSC-373076); (R-SSC-418594)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "G-protein coupled receptor for cannabinoids, including endocannabinoids (eCBs), such as N-arachidonoylethanolamide (also called anandamide or AEA) and 2-arachidonoylglycerol (2-AG). Signaling typically involves reduction in cyclic AMP., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8D1ZJJ4", "ec_number_list": "", "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0042802 identical protein binding;GO:0004949 cannabinoid receptor activity", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0098982 GABA-ergic synapse;GO:0005737 cytoplasm;GO:0005741 mitochondrial outer membrane;GO:0005886 plasma membrane", "go_biological_process": "GO:0098921 retrograde trans-synaptic signaling by endocannabinoid;GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0099509 regulation of presynaptic cytosolic calcium ion concentration", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1S0E6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1S0M4-1", "uniprot_id": "F1S0M4_PIG", "mass": 71037.0, "length": 637, "protein_name": "Huntingtin associated protein 1", "gene_name": "HAP1", "organism": "Pig", "refseq_name": "huntingtin-associated protein 1 isoform X1", "refseq_ac": "XP_013836418", "gene_names_uniprotkb": "HAP1", "gene_names_refseq": "HAP1", "protein_names_uniprotkb": "Huntingtin associated protein 1", "protein_names_refseq": "huntingtin-associated protein 1 isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100736934)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005102 signaling receptor binding;GO:0017022 myosin binding", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005813 centrosome;GO:0005829 cytosol;GO:0030425 dendrite;GO:0031410 cytoplasmic vesicle", "go_biological_process": "GO:0006605 protein targeting;GO:0050850 positive regulation of calcium-mediated signaling;GO:0008089 anterograde axonal transport;GO:0008104 intracellular protein localization;GO:0048011 neurotrophin TRK receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1S0M4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1S0N7-1", "uniprot_id": "F1S0N7_PIG", "mass": 35511.0, "length": 312, "protein_name": "Protein odd-skipped-related 2", "gene_name": "OSR2", "organism": "Pig", "refseq_name": "protein odd-skipped-related 2 isoform X1", "refseq_ac": "XP_001928833", "gene_names_uniprotkb": "OSR2", "gene_names_refseq": "OSR2", "protein_names_uniprotkb": "Protein odd-skipped-related 2", "protein_names_refseq": "protein odd-skipped-related 2 isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100155180)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "May be involved in the development of the mandibular molar tooth germ at the bud stage., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, 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"reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "K7GMB7", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0005524 ATP binding;GO:0008270 zinc ion binding;GO:0016887 ATP hydrolysis activity;GO:0003725 double-stranded RNA binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005794 Golgi apparatus;GO:0005829 cytosol", "go_biological_process": "GO:1900245 positive regulation of MDA-5 signaling pathway;GO:1900246 positive regulation of RIG-I signaling pathway;GO:0032481 positive regulation of type I interferon production;GO:0039534 negative regulation of MDA-5 signaling pathway;GO:0039536 negative regulation of RIG-I signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1S0P6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1S1A6-1", "uniprot_id": "F1S1A6_PIG", "mass": 45103.0, "length": 402, "protein_name": "Beta-1,4-galactosyltransferase", "gene_name": "B4GALT3", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "B4GALT3", "gene_names_refseq": "", "protein_names_uniprotkb": "Beta-1,4-galactosyltransferase; 2.4.1.-; Beta-1,4-GalTase", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-2022854); (R-SSC-975577)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008378 galactosyltransferase activity;GO:0046872 metal ion binding;GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity;GO:0003945 N-acetyllactosamine synthase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005794 Golgi apparatus;GO:0032580 Golgi cisterna membrane", "go_biological_process": "GO:0005975 carbohydrate metabolic process;GO:0009101 glycoprotein biosynthetic process;GO:0006682 galactosylceramide biosynthetic process;GO:0006678 glucosylceramide metabolic process", "synthesized_glycan_count": 10105, "hit_score": 0.2, "record_id": "F1S1A6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1S2A8-1", "uniprot_id": "F1S2A8_PIG", "mass": 27859.0, "length": 246, "protein_name": "B-cell receptor-associated protein", "gene_name": "BCAP31", "organism": "Pig", "refseq_name": "B-cell receptor-associated protein 31 isoform X2", "refseq_ac": "XP_003135528", "gene_names_uniprotkb": "BCAP31", "gene_names_refseq": "BCAP31", "protein_names_uniprotkb": "B-cell receptor-associated protein; BCR-associated protein", "protein_names_refseq": "B-cell receptor-associated protein 31 isoform X2", "tax_id": 9823, "disease": "", "pathway": " (ssc:100520774); (R-SSC-111465); (R-SSC-75153); (R-SSC-8980692); (R-SSC-983170)", "pathway_count": 5, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Plays a role in the export of secreted proteins in the ER., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0044877 protein-containing complex binding;GO:0042288 MHC class I protein binding", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005811 lipid droplet;GO:0005886 plasma membrane;GO:0097038 perinuclear endoplasmic reticulum;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0007283 spermatogenesis;GO:0006915 apoptotic process;GO:0006626 protein targeting to mitochondrion;GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1S2A8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1S3B8-1", "uniprot_id": "F1S3B8_PIG", "mass": 87827.0, "length": 800, "protein_name": "Fibroblast growth factor receptor", "gene_name": "FGFR4", "organism": "Pig", "refseq_name": "fibroblast growth factor receptor 4", "refseq_ac": "XP_003123730", "gene_names_uniprotkb": "FGFR4", "gene_names_refseq": "FGFR4", "protein_names_uniprotkb": "Fibroblast growth factor receptor; 2.7.10.1", "protein_names_refseq": "fibroblast growth factor receptor 4", "tax_id": 9823, "disease": "", "pathway": " (ssc:100127133); (R-SSC-109704); (R-SSC-1257604); (R-SSC-1307965); (R-SSC-190322); (R-SSC-5654228); (R-SSC-5654712); (R-SSC-5654719); (R-SSC-5654720); (R-SSC-5654733); (R-SSC-5673001); (R-SSC-6811558)", "pathway_count": 12, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A480WPL5", "ec_number_list": "", "go_molecular_function": "GO:0005007 fibroblast growth factor receptor activity;GO:0005524 ATP binding;GO:0008201 heparin binding;GO:0017134 fibroblast growth factor binding", "go_cellular_component": "GO:0005768 endosome;GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0005886 plasma membrane;GO:0005911 cell-cell junction", "go_biological_process": "GO:0070857 regulation of bile acid biosynthetic process;GO:0008284 positive regulation of cell population proliferation;GO:0010628 positive regulation of gene expression;GO:0016477 cell migration;GO:0070374 positive regulation of ERK1 and ERK2 cascade", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1S3B8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1S3L9-1", "uniprot_id": "F1S3L9_PIG", "mass": 132336.0, "length": 1184, "protein_name": "Tyrosine-protein kinase", "gene_name": "TYK2", "organism": "Pig", "refseq_name": "non-receptor tyrosine-protein kinase TYK2 isoform X1", "refseq_ac": "XP_005654882", "gene_names_uniprotkb": "TYK2", "gene_names_refseq": "TYK2", "protein_names_uniprotkb": "Tyrosine-protein kinase; 2.7.10.2", "protein_names_refseq": "non-receptor tyrosine-protein kinase TYK2 isoform X1", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-1059683); (R-SSC-112411); (R-SSC-449836); (R-SSC-6783783); (R-SSC-6785807); (R-SSC-6788467); (R-SSC-8854691); (R-SSC-8984722); (R-SSC-9020591); (R-SSC-9020933); (R-SSC-9020956); (R-SSC-909733); (R-SSC-912694); (R-SSC-9674555); (R-SSC-9705462); (R-SSC-9958825)", "pathway_count": 16, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A287ASU9", "ec_number_list": "", "go_molecular_function": "GO:0004715 non-membrane spanning protein tyrosine kinase activity;GO:0005524 ATP binding;GO:0005131 growth hormone receptor binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0005856 cytoskeleton;GO:0016020 membrane", "go_biological_process": "GO:0008283 cell population proliferation;GO:0030154 cell differentiation;GO:0035556 intracellular signal transduction;GO:0060333 type II interferon-mediated signaling pathway;GO:0060337 type I interferon-mediated signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1S3L9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1S3P6-1", "uniprot_id": "F1S3P6_PIG", "mass": 37934.0, "length": 349, "protein_name": "CCN family member 2", "gene_name": "CCN2", "organism": "Pig", "refseq_name": "CCN family member 2 precursor", "refseq_ac": "NP_998998", "gene_names_uniprotkb": "CCN2", "gene_names_refseq": "CCN2; CTGF", "protein_names_uniprotkb": "CCN family member 2; Cellular communication network factor 2; Connective tissue growth factor", "protein_names_refseq": "CCN family member 2 precursor; CCN family member 2; connective tissue growth factor", "tax_id": 9823, "disease": "", "pathway": " (ssc:100152141)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "17093396;17694440;21576830;24079812;31476383;32543654", "class_list": "", "function": "Atrial fibrillation patients and animals exhibited a significantly increased expression of connective tissue growth factor (CTGF). Angiotension II-induced CTGF expression might be involved in atrial substrate remodeling., [RefSeq, PubMed]; CCN2 was transiently expressed at the leading keratinocyte edge in wound healing., [RefSeq, PubMed]; CTGF in trabecular meshwork is modulated by physiological agonists and by increased ocular pressure and mechanical stretch. Regulation of CTGF within outflow pathway may play role in homeostasis of intraocular pressure. Publication Status: Online-Only, [RefSeq, PubMed]; CTGF level was not altered in model of obliterative bronchiolitis., [RefSeq, PubMed]; Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Is involved in the stimulation of osteoblast differentiation and has a critical role in osteogenesis. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis., [UniProtKB, UniProtKB]; This study provides evidence for the circINHA/miR-10a-5p/CTGF regulatory pathway in follicular GC apoptosis and provides novel insights into the role of circRNAs in the modulation of ovarian physiological functions., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005178 integrin binding;GO:0008201 heparin binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0031012 extracellular matrix", "go_biological_process": "GO:0071897 DNA biosynthetic process;GO:0007155 cell adhesion;GO:0007165 signal transduction;GO:0046330 positive regulation of JNK cascade;GO:0070374 positive regulation of ERK1 and ERK2 cascade", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "F1S3P6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1S4H9-1", "uniprot_id": "F1S4H9_PIG", "mass": 137953.0, "length": 1227, "protein_name": "Cytosolic carboxypeptidase 1", "gene_name": "AGTPBP1", "organism": "Pig", "refseq_name": "cytosolic carboxypeptidase 1 isoform X1", "refseq_ac": "XP_005656862", "gene_names_uniprotkb": "AGTPBP1", "gene_names_refseq": "AGTPBP1", "protein_names_uniprotkb": "Cytosolic carboxypeptidase 1; 3.4.17.24; ATP/GTP-binding protein 1; Protein deglutamylase CCP1", "protein_names_refseq": "cytosolic carboxypeptidase 1 isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100518857)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Metallocarboxypeptidase that mediates protein deglutamylation of tubulin and non-tubulin target proteins. Catalyzes the removal of polyglutamate side chains present on the gamma-carboxyl group of glutamate residues within the C-terminal tail of alpha- and beta-tubulin. Specifically cleaves tubulin long-side-chains, while it is not able to remove the branching point glutamate. Also catalyzes the removal of polyglutamate residues from the carboxy-terminus of alpha-tubulin as well as non-tubulin proteins such as MYLK. Involved in KLF4 deglutamylation which promotes KLF4 proteasome-mediated degradation, thereby negatively regulating cell pluripotency maintenance and embryogenesis., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0004181 metallocarboxypeptidase activity;GO:0015631 tubulin binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005829 cytosol", "go_biological_process": "GO:0006508 proteolysis;GO:0050905 neuromuscular process;GO:0007005 mitochondrion organization;GO:0001754 eye photoreceptor cell differentiation;GO:0021772 olfactory bulb development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1S4H9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1S4P6-1", "uniprot_id": "F1S4P6_PIG", "mass": 166058.0, "length": 1376, "protein_name": "Eukaryotic translation initiation factor 3 subunit A", "gene_name": "EIF3A", "organism": "Pig", "refseq_name": "eukaryotic translation initiation factor 3 subunit A", "refseq_ac": "XP_001928377", "gene_names_uniprotkb": "EIF3A; EIF3S10", "gene_names_refseq": "EIF3A", "protein_names_uniprotkb": "Eukaryotic translation initiation factor 3 subunit A; Eukaryotic translation initiation factor 3 subunit 10; eIF-3-theta; eIF3a", "protein_names_refseq": "eukaryotic translation initiation factor 3 subunit A", "tax_id": 9823, "disease": "", "pathway": " (ssc:100156570); (R-SSC-156827); (R-SSC-72649); (R-SSC-72689); (R-SSC-72695); (R-SSC-72702)", "pathway_count": 6, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression., [UniProtKB, HAMAP, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003729 mRNA binding;GO:0003743 translation initiation factor activity", "go_cellular_component": "GO:0005829 cytosol;GO:0014069 postsynaptic density;GO:0016282 eukaryotic 43S preinitiation complex;GO:0033290 eukaryotic 48S preinitiation complex;GO:0043614 multi-eIF complex", "go_biological_process": "GO:0002188 translation reinitiation;GO:0075522 IRES-dependent viral translational initiation;GO:0001732 formation of cytoplasmic translation initiation complex;GO:0075525 viral translational termination-reinitiation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1S4P6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1S550-1", "uniprot_id": "F1S550_PIG", "mass": 111472.0, "length": 1025, "protein_name": "Dihydropyrimidine dehydrogenase [NADP(+)]", "gene_name": "DPYD", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "DPYD", "gene_names_refseq": "", "protein_names_uniprotkb": "Dihydropyrimidine dehydrogenase [NADP(+)]; 1.3.1.2; DHPDHase; DPD; Dihydrothymine dehydrogenase; Dihydrouracil dehydrogenase", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-73621)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0002058 uracil binding;GO:0017113 dihydropyrimidine dehydrogenase (NADP+) activity;GO:0042803 protein homodimerization activity;GO:0046872 metal ion binding;GO:0051539 4 iron, 4 sulfur cluster binding", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0046079 dUMP catabolic process;GO:0006145 purine nucleobase catabolic process;GO:0006210 thymine catabolic process;GO:0006212 uracil catabolic process;GO:0006214 thymidine catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1S550-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1S567-1", "uniprot_id": "F1S567_PIG", "mass": 58650.0, "length": 537, "protein_name": "Vascular cell adhesion molecule 1", "gene_name": "VCAM1", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "VCAM1", "gene_names_refseq": "", "protein_names_uniprotkb": "Vascular cell adhesion molecule 1", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-198933); (R-SSC-216083)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005178 integrin binding;GO:0008131 primary methylamine oxidase activity;GO:0098631 cell adhesion mediator activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005769 early endosome;GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0005886 plasma membrane", "go_biological_process": "GO:0022614 membrane to membrane docking;GO:0006954 inflammatory response;GO:0007155 cell adhesion;GO:1904646 cellular response to amyloid-beta;GO:0007160 cell-matrix adhesion", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1S567-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1S584-1", "uniprot_id": "CTL2_PIG", "mass": 80238.0, "length": 706, "protein_name": "Choline transporter-like protein 2", "gene_name": "SLC44A2", "organism": "Pig", "refseq_name": "choline transporter-like protein 2 isoform 2", "refseq_ac": "XP_003123258", "gene_names_uniprotkb": "SLC44A2; CTL2", "gene_names_refseq": "CTL2; SLC44A2", "protein_names_uniprotkb": "Choline transporter-like protein 2; Solute carrier family 44 member 2", "protein_names_refseq": "Choline transporter-like protein 2; choline transporter-like protein 2 isoform 2; solute carrier family 44, member 2 tv2", "tax_id": 9823, "disease": "", "pathway": " (ssc:100524730); (R-SSC-1483191); (R-SSC-6798163); (R-SSC-6798695); (R-SSC-9958517)", "pathway_count": 5, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Choline/H+ antiporter, mainly in mitochondria. Also acts as a low-affinity ethanolamine/H+ antiporter, regulating the supply of extracellular ethanolamine (Etn) for the CDP-Etn pathway, redistribute intracellular Etn and balance the CDP-Cho and CDP-Etn arms of the Kennedy pathway., [UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 2, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0022857 transmembrane transporter activity;GO:0015297 antiporter activity;GO:0015220 choline transmembrane transporter activity;GO:0034228 ethanolamine transmembrane transporter activity", "go_cellular_component": "GO:0005741 mitochondrial outer membrane;GO:0005886 plasma membrane;GO:0016020 membrane", "go_biological_process": "GO:0055085 transmembrane transport;GO:0015871 choline transport;GO:0034229 ethanolamine transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1S584-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1S5G3-1", "uniprot_id": "F1S5G3_PIG", "mass": 51675.0, "length": 471, "protein_name": "D(1A) dopamine receptor", "gene_name": "DRD5", "organism": "Pig", "refseq_name": "D(1B) dopamine receptor", "refseq_ac": "XP_013844738", "gene_names_uniprotkb": "DRD5", "gene_names_refseq": "DRD5", "protein_names_uniprotkb": "D(1A) dopamine receptor; D(1B) dopamine receptor; D(5) dopamine receptor; Dopamine D1 receptor; Dopamine D5 receptor", "protein_names_refseq": "D(1B) dopamine receptor", "tax_id": 9823, "disease": "", "pathway": " (ssc:100524631); (R-SSC-390651)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase. Forms heterotetramers with DRD3 to potentiate beta-arrestin recruitment and mediate locomotor activity., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0035240 dopamine binding;GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs", "go_cellular_component": "GO:0005886 plasma membrane;GO:0043197 dendritic spine;GO:0005789 endoplasmic reticulum membrane;GO:0031526 brush border membrane;GO:0060170 ciliary membrane", "go_biological_process": "GO:0043410 positive regulation of MAPK cascade;GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway;GO:0008217 regulation of blood pressure;GO:0007212 G protein-coupled dopamine receptor signaling pathway;GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1S5G3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1S5H5-1", "uniprot_id": "F1S5H5_PIG", "mass": 50155.0, "length": 469, "protein_name": "Beta-1 adrenergic receptor", "gene_name": "ADRB1", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "ADRB1", "gene_names_refseq": "", "protein_names_uniprotkb": "Beta-1 adrenergic receptor; Beta-1 adrenoreceptor", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-390696)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "G protein-coupled receptor for catecholamines that couples to G(s) proteins to activate adenylate cyclase and cAMP-dependent pathway. Binds epinephrine and norepinephrine with approximately equal affinity. Mediates the activation of Ras via binding with cAMP-dependent RAPGEF2. As part of the sympathetic nervous system, plays a role in the physiologic regulation of cardiac functions such as stimulation of cardiomyocyte contraction. Also delivers proapoptotic signals in cardiomyocytes. Involved in the regulation of sleep/wake behaviors., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A7BJV9", "ec_number_list": "", "go_molecular_function": "GO:0046982 protein heterodimerization activity;GO:0031694 alpha-2A adrenergic receptor binding;GO:0030165 PDZ domain binding;GO:0004940 beta1-adrenergic receptor activity;GO:0099579 G protein-coupled neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential", "go_cellular_component": "GO:0098992 neuronal dense core vesicle;GO:0005769 early endosome;GO:0005886 plasma membrane;GO:0098685 Schaffer collateral - CA1 synapse", "go_biological_process": "GO:0045187 regulation of circadian sleep/wake cycle, sleep;GO:0043410 positive regulation of MAPK cascade;GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway;GO:0002025 norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure;GO:0001996 positive regulation of heart rate by epinephrine-norepinephrine", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1S5H5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1S5K5-1", "uniprot_id": "F1S5K5_PIG", "mass": 32699.0, "length": 296, "protein_name": "SIX homeobox 2", "gene_name": "SIX2", "organism": "Pig", "refseq_name": "homeobox protein SIX2 isoform X2", "refseq_ac": "XP_003125222", "gene_names_uniprotkb": "SIX2", "gene_names_refseq": "SIX2", "protein_names_uniprotkb": "SIX homeobox 2", "protein_names_refseq": "homeobox protein SIX2 isoform X2", "tax_id": 9823, "disease": "", "pathway": " (ssc:100525814)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, 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binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005667 transcription regulator complex", "go_biological_process": "GO:0007501 mesodermal cell fate specification;GO:0072038 mesenchymal stem cell maintenance involved in nephron morphogenesis;GO:0090189 regulation of branching involved in ureteric bud morphogenesis;GO:0097168 mesenchymal stem cell proliferation;GO:0006357 regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1S5K5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1S747-1", "uniprot_id": "F1S747_PIG", "mass": 25000.0, "length": 226, "protein_name": "Ras-related protein Rab", "gene_name": "RAB32", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "RAB32", "gene_names_refseq": "", "protein_names_uniprotkb": "Ras-related protein Rab", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "The small GTPases Rab are key regulators in vesicle trafficking., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0035651 AP-3 adaptor complex binding;GO:0036461 BLOC-2 complex binding;GO:0005525 GTP binding;GO:0030742 GTP-dependent protein binding;GO:0035650 AP-1 adaptor complex binding", "go_cellular_component": "GO:0005741 mitochondrial outer membrane;GO:0005769 early endosome;GO:0005783 endoplasmic reticulum;GO:0005764 lysosome;GO:0030670 phagocytic vesicle membrane", "go_biological_process": "GO:1903232 melanosome assembly;GO:0008333 endosome to lysosome transport;GO:0035646 endosome to melanosome transport;GO:0072657 protein localization to membrane;GO:0007005 mitochondrion organization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1S747-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1S8V5-1", "uniprot_id": "F1S8V5_PIG", "mass": 68098.0, "length": 594, "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit alpha", "gene_name": "CHUK", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "CHUK", "gene_names_refseq": "", "protein_names_uniprotkb": "Inhibitor of nuclear factor kappa-B kinase subunit alpha; 2.7.11.10; Nuclear factor NF-kappa-B inhibitor kinase alpha", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-1169091); (R-SSC-1810476); (R-SSC-202424); (R-SSC-2871837); (R-SSC-445989); (R-SSC-5357905); (R-SSC-5357956); (R-SSC-5607761); (R-SSC-5607764); (R-SSC-5676590); (R-SSC-5684264); (R-SSC-9020702); (R-SSC-933542); (R-SSC-937039); (R-SSC-937041); (R-SSC-975144); (R-SSC-9758274); (R-SSC-9833482); (R-SSC-9860276); (R-SSC-9860927); (R-SSC-9909505)", "pathway_count": 21, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "F1S8V4", "ec_number_list": "", "go_molecular_function": "GO:0008384 IkappaB kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0042803 protein homodimerization activity;GO:0046982 protein heterodimerization activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0008385 IkappaB kinase complex", "go_biological_process": "GO:0032727 positive regulation of interferon-alpha production;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0043123 positive regulation of canonical NF-kappaB signal transduction;GO:0033209 tumor necrosis factor-mediated signaling pathway;GO:0038061 non-canonical NF-kappaB signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1S8V5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1S9I4-1", "uniprot_id": "F1S9I4_PIG", "mass": 52487.0, "length": 482, "protein_name": "Dual specificity protein phosphatase 10", "gene_name": "DUSP10", "organism": "Pig", "refseq_name": "dual specificity protein phosphatase 10", "refseq_ac": "XP_003130558", "gene_names_uniprotkb": "DUSP10", "gene_names_refseq": "DUSP10", "protein_names_uniprotkb": "Dual specificity protein phosphatase 10; 3.1.3.16; 3.1.3.48", "protein_names_refseq": "dual specificity protein phosphatase 10", "tax_id": 9823, "disease": "", "pathway": " (ssc:100517416); (R-SSC-112409); (R-SSC-5675221)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Protein phosphatase involved in the inactivation of MAP kinases. Has a specificity for the MAPK11/MAPK12/MAPK13/MAPK14 subfamily. It preferably dephosphorylates p38., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A4X1TKZ2", "ec_number_list": "", "go_molecular_function": "GO:0004722 protein serine/threonine phosphatase activity;GO:0048273 mitogen-activated protein kinase p38 binding;GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity;GO:0008330 protein tyrosine/threonine phosphatase activity;GO:0008432 JUN kinase binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0010633 negative regulation of epithelial cell migration;GO:0050680 negative regulation of epithelial cell proliferation;GO:0070373 negative regulation of ERK1 and ERK2 cascade;GO:0046329 negative regulation of JNK cascade;GO:1903753 negative regulation of p38MAPK cascade", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1S9I4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SA26-1", "uniprot_id": "F1SA26_PIG", "mass": 38570.0, "length": 354, "protein_name": "Arginase", "gene_name": "ARG2", "organism": "Pig", "refseq_name": "arginase-2, mitochondrial isoform X1", "refseq_ac": "XP_001928714", "gene_names_uniprotkb": "ARG2", "gene_names_refseq": "ARG2", "protein_names_uniprotkb": "Arginase; 3.5.3.1", "protein_names_refseq": "arginase-2, mitochondrial isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100155893); (R-SSC-70635); (R-SSC-9837999)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A4X1U8K8", "ec_number_list": "", "go_molecular_function": "GO:0030145 manganese ion binding;GO:0004053 arginase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion", "go_biological_process": "GO:0032700 negative regulation of interleukin-17 production;GO:0032651 regulation of interleukin-1 beta production;GO:0032720 negative regulation of tumor necrosis factor production;GO:0000050 urea cycle;GO:0001657 ureteric bud development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SA26-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SA54-1", "uniprot_id": "F1SA54_PIG", "mass": 67176.0, "length": 581, "protein_name": "Alpha-(1,6)-fucosyltransferase", "gene_name": "FUT8", "organism": "Pig", "refseq_name": "alpha-(1,6)-fucosyltransferase isoform X1", "refseq_ac": "XP_005666378", "gene_names_uniprotkb": "FUT8", "gene_names_refseq": "FUT8", "protein_names_uniprotkb": "Alpha-(1,6)-fucosyltransferase; 2.4.1.68", "protein_names_refseq": "alpha-(1,6)-fucosyltransferase isoform X1", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-975578)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans. Fucosylates the reducing GlcNAc residue in complex-type N-glycans attached on the fragment crystallizable (Fc) of IgGs. Fully converts Fc glycoforms containing one or two terminal GlcNAc moieties (G0-GlcNAc and G0)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0046921 alpha-(1->6)-fucosyltransferase activity;GO:0017124 SH3 domain binding;GO:0008424 glycoprotein 6-alpha-L-fucosyltransferase activity", "go_cellular_component": "GO:0032580 Golgi cisterna membrane", "go_biological_process": "GO:0006487 protein N-linked glycosylation;GO:0046368 GDP-L-fucose metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SA54-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SA75-1", "uniprot_id": "F1SA75_PIG", "mass": 47179.0, "length": 427, "protein_name": "A-kinase anchoring protein 5", "gene_name": "AKAP5", "organism": "Pig", "refseq_name": "A-kinase anchor protein 5", "refseq_ac": "XP_013833739", "gene_names_uniprotkb": "AKAP5", "gene_names_refseq": "AKAP5", "protein_names_uniprotkb": "A-kinase anchoring protein 5", "protein_names_refseq": "A-kinase anchor protein 5", "tax_id": 9823, "disease": "", "pathway": " (ssc:100153460); (R-SSC-399719)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0031698 beta-2 adrenergic receptor binding;GO:0060090 molecular adaptor activity;GO:0005516 calmodulin binding;GO:0017124 SH3 domain binding;GO:0008179 adenylate cyclase binding", "go_cellular_component": "GO:0098837 postsynaptic recycling endosome;GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0014069 postsynaptic density;GO:0043197 dendritic spine", "go_biological_process": "GO:0007193 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway;GO:1900273 positive regulation of long-term synaptic potentiation;GO:1903538 regulation of meiotic cell cycle process involved in oocyte maturation;GO:0033173 calcineurin-NFAT signaling cascade;GO:1905751 positive regulation of endosome to plasma membrane protein transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SA75-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SAH7-1", "uniprot_id": "F1SAH7_PIG", "mass": 107642.0, "length": 941, "protein_name": "Vacuolar protein sorting-associated protein 11 homolog", "gene_name": "VPS11", "organism": "Pig", "refseq_name": "vacuolar protein sorting-associated protein 11 homolog isoform X1", "refseq_ac": "XP_003129971", "gene_names_uniprotkb": "VPS11", "gene_names_refseq": "VPS11", "protein_names_uniprotkb": "Vacuolar protein sorting-associated protein 11 homolog", "protein_names_refseq": "vacuolar protein sorting-associated protein 11 homolog isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100517049)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0030674 protein-macromolecule adaptor activity;GO:0000166 nucleotide binding", "go_cellular_component": "GO:0030897 HOPS complex;GO:0005768 endosome;GO:0005769 early endosome;GO:0005884 actin filament;GO:0005765 lysosomal membrane", "go_biological_process": "GO:0048284 organelle fusion;GO:0006886 intracellular protein transport;GO:0006914 autophagy;GO:0007032 endosome organization;GO:0007033 vacuole organization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SAH7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SBE6-1", "uniprot_id": "F1SBE6_PIG", "mass": 96088.0, "length": 858, "protein_name": "Potassium voltage-gated channel subfamily B member 1", "gene_name": "KCNB1", "organism": "Pig", "refseq_name": "potassium voltage-gated channel subfamily B member 1 isoform X1", "refseq_ac": "XP_020932946", "gene_names_uniprotkb": "KCNB1", "gene_names_refseq": "DRK1; KCNB1", "protein_names_uniprotkb": "Potassium voltage-gated channel subfamily B member 1; Voltage-gated potassium channel subunit Kv2.1", "protein_names_refseq": "potassium voltage-gated channel subfamily B member 1 isoform X1", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-1296072); (R-SSC-381676)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005251 delayed rectifier potassium channel activity;GO:0015459 potassium channel regulator activity;GO:0044325 transmembrane transporter binding", "go_cellular_component": "GO:0030424 axon;GO:0043204 perikaryon;GO:0045211 postsynaptic membrane;GO:0008076 voltage-gated potassium channel complex;GO:0042383 sarcolemma", "go_biological_process": "GO:0098900 regulation of action potential;GO:0051260 protein homooligomerization;GO:0071333 cellular response to glucose stimulus;GO:0001508 action potential;GO:0046676 negative regulation of insulin secretion", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SBE6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SBJ0-1", "uniprot_id": "F1SBJ0_PIG", "mass": 73081.0, "length": 649, "protein_name": "Leucine-rich repeat transmembrane protein FLRT3", "gene_name": "FLRT3", "organism": "Pig", "refseq_name": "leucine-rich repeat transmembrane protein FLRT3", "refseq_ac": "XP_001926484", "gene_names_uniprotkb": "FLRT3", "gene_names_refseq": "FLRT3", "protein_names_uniprotkb": "Leucine-rich repeat transmembrane protein FLRT3", "protein_names_refseq": "leucine-rich repeat transmembrane protein FLRT3", "tax_id": 9823, "disease": "", "pathway": " (ssc:100158214); (R-SSC-5654687)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "K7GQG6", "ec_number_list": "", "go_molecular_function": "GO:0042803 protein homodimerization activity;GO:0045499 chemorepellent activity;GO:0005104 fibroblast growth factor receptor binding", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0032584 growth cone membrane;GO:0005615 extracellular space;GO:0005911 cell-cell junction;GO:0005925 focal adhesion", "go_biological_process": "GO:0007416 synapse assembly;GO:0007411 axon guidance;GO:0099560 synaptic membrane adhesion;GO:0003345 proepicardium cell migration involved in pericardium morphogenesis;GO:1990138 neuron projection extension", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SBJ0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SCT4-1", "uniprot_id": "F1SCT4_PIG", "mass": 57125.0, "length": 495, "protein_name": "Cytochrome P450 2E1", "gene_name": "CYP2E1", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "CYP2E1", "gene_names_refseq": "", "protein_names_uniprotkb": "Cytochrome P450 2E1; 1.14.13.n7; 1.14.14.1", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-211981); (R-SSC-211999); (R-SSC-9027307); (R-SSC-9749641); (R-SSC-9753281)", "pathway_count": 5, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "A cytochrome P450 monooxygenase involved in the metabolism of fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates fatty acids specifically at the omega-1 position displaying the highest catalytic activity for saturated fatty acids. May be involved in the oxidative metabolism of xenobiotics., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0051879 Hsp90 protein binding;GO:0030544 Hsp70 protein binding;GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005743 mitochondrial inner membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006805 xenobiotic metabolic process;GO:0019373 epoxygenase P450 pathway;GO:0002933 lipid hydroxylation;GO:0016098 monoterpenoid metabolic process;GO:0001676 long-chain fatty acid metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SCT4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SD72-1", "uniprot_id": "F1SD72_PIG", "mass": 68808.0, "length": 619, "protein_name": "Solute carrier family 24 member 4", "gene_name": "SLC24A4", "organism": "Pig", "refseq_name": "sodium/potassium/calcium exchanger 4 isoform X1", "refseq_ac": "XP_003128741", "gene_names_uniprotkb": "SLC24A4", "gene_names_refseq": "SLC24A4", "protein_names_uniprotkb": "Solute carrier family 24 member 4", "protein_names_refseq": "sodium/potassium/calcium exchanger 4 isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100156914); (R-SSC-425561)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005262 calcium channel activity;GO:0005516 calmodulin binding;GO:0048306 calcium-dependent protein binding;GO:0015293 symporter activity;GO:0008273 calcium, potassium:sodium antiporter activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0016324 apical plasma membrane;GO:0031982 vesicle;GO:0120199 cone photoreceptor outer segment", "go_biological_process": "GO:0050849 negative regulation of calcium-mediated signaling;GO:0006874 intracellular calcium ion homeostasis;GO:0007608 sensory perception of smell;GO:0070588 calcium ion transmembrane transport;GO:0071486 cellular response to high light intensity", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SD72-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SDC3-1", "uniprot_id": "F1SDC3_PIG", "mass": 40451.0, "length": 358, "protein_name": "Gap junction protein", "gene_name": "GJA5", "organism": "Pig", "refseq_name": "gap junction alpha-5 protein", "refseq_ac": "XP_001928335", "gene_names_uniprotkb": "GJA5", "gene_names_refseq": "GJA5", "protein_names_uniprotkb": "Gap junction protein", "protein_names_refseq": "gap junction alpha-5 protein", "tax_id": 9823, "disease": "", "pathway": " (ssc:100157795); (R-SSC-190861)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell., [UniProtKB, UniProtKB]; Structural component of the gap junction, a specialized intercellular structure consisting of a cluster of closely packed pairs of transmembrane channels, the connexons, that allow passage of small molecules and electrical signals between neighboring cells. Forms homotypic and heterotypic channels gated by transjunctional voltage. Involved in intercellular innate immune signaling. Mediates translocation of 2',3'-cGAMP and 2',5'-oligoadenylates (2-5A) second messengers from virus-infected cells to macrophages and uninfected neighboring cells to propagate and amplify the antiviral immune response., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A4X1SLG1", "ec_number_list": "", "go_molecular_function": "GO:0055077 gap junction hemi-channel activity;GO:0086076 gap junction channel activity involved in atrial cardiac muscle cell-AV node cell electrical coupling;GO:0086077 gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling;GO:0086078 gap junction channel activity involved in bundle of His cell-Purkinje myocyte electrical coupling", "go_cellular_component": "GO:0014704 intercalated disc;GO:0005922 connexin complex", "go_biological_process": "GO:0001525 angiogenesis;GO:0007267 cell-cell signaling;GO:0007507 heart development;GO:0003281 ventricular septum development;GO:0003283 atrial septum development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SDC3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SDX2-1", "uniprot_id": "F1SDX2_PIG", "mass": 57508.0, "length": 526, "protein_name": "Vesicular inhibitory amino acid transporter", "gene_name": "SLC32A1", "organism": "Pig", "refseq_name": "vesicular inhibitory amino acid transporter", "refseq_ac": "XP_003134485", "gene_names_uniprotkb": "SLC32A1", "gene_names_refseq": "SLC32A1", "protein_names_uniprotkb": "Vesicular inhibitory amino acid transporter; Solute carrier family 32 member 1; Vesicular GABA transporter", "protein_names_refseq": "vesicular inhibitory amino acid transporter", "tax_id": 9823, "disease": "", "pathway": " (ssc:100517013); (R-SSC-442660); (R-SSC-888590)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Antiporter that exchanges vesicular protons for cytosolic 4-aminobutanoate or to a lesser extend glycine, thus allowing their secretion from nerve terminals. The transport is equally dependent on the chemical and electrical components of the proton gradient. May also transport beta-alanine. Acidification of GABAergic synaptic vesicles is a prerequisite for 4-aminobutanoate uptake., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0015187 glycine transmembrane transporter activity;GO:0140799 glycine:proton antiporter activity;GO:0140800 gamma-aminobutyric acid:proton antiporter activity", "go_cellular_component": "GO:0051286 cell tip;GO:0009986 cell surface;GO:0048786 presynaptic active zone;GO:0030672 synaptic vesicle membrane;GO:0060077 inhibitory synapse", "go_biological_process": "GO:0015816 glycine transport;GO:0015812 gamma-aminobutyric acid transport;GO:0051939 gamma-aminobutyric acid import;GO:0098700 neurotransmitter loading into synaptic vesicle", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SDX2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SE73-1", "uniprot_id": "F1SE73_PIG", "mass": 44868.0, "length": 397, "protein_name": "DnaJ homolog subfamily A member 1", "gene_name": "DNAJA1", "organism": "Pig", "refseq_name": "dnaJ homolog subfamily A member 1 isoform X1", "refseq_ac": "XP_020919646", "gene_names_uniprotkb": "DNAJA1", "gene_names_refseq": "DNAJA1", "protein_names_uniprotkb": "DnaJ homolog subfamily A member 1", "protein_names_refseq": "dnaJ homolog subfamily A member 1 isoform X1", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-3371497); (R-SSC-9841251)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A4X1UQT0", "ec_number_list": "", "go_molecular_function": "GO:0055131 C3HC4-type RING finger domain binding;GO:0005524 ATP binding;GO:0008270 zinc ion binding;GO:0050750 low-density lipoprotein particle receptor binding;GO:0051082 unfolded protein binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005739 mitochondrion;GO:0005829 cytosol;GO:0016020 membrane;GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "GO:0051223 regulation of protein transport;GO:0070585 protein localization to mitochondrion;GO:1903748 negative regulation of establishment of protein localization to mitochondrion;GO:1905259 negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway;GO:0043065 positive regulation of apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SE73-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SFP4-1", "uniprot_id": "F1SFP4_PIG", "mass": 92795.0, "length": 859, "protein_name": "Mitogen-activated protein kinase kinase kinase 12", "gene_name": "MAP3K12", "organism": "Pig", "refseq_name": "mitogen-activated protein kinase kinase kinase 12 isoform X2", "refseq_ac": "XP_005652627", "gene_names_uniprotkb": "MAP3K12", "gene_names_refseq": "MAP3K12", "protein_names_uniprotkb": "Mitogen-activated protein kinase kinase kinase 12; 2.7.11.25", "protein_names_refseq": "mitogen-activated protein kinase kinase kinase 12 isoform X2", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "May be an activator of the JNK/SAPK pathway., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "A0A8D0RZV2", "ec_number_list": "", "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0019901 protein kinase binding;GO:0042803 protein homodimerization activity;GO:0043539 protein serine/threonine kinase activator activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0030426 growth cone", "go_biological_process": "GO:0043687 post-translational protein modification;GO:0070374 positive regulation of ERK1 and ERK2 cascade;GO:0007254 JNK cascade;GO:0045893 positive regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SFP4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SG05-1", "uniprot_id": "F1SG05_PIG", "mass": 67832.0, "length": 629, "protein_name": "dual-specificity kinase", "gene_name": "TESK1", "organism": "Pig", "refseq_name": "dual specificity testis-specific protein kinase 1 isoform X1", "refseq_ac": "XP_003122032", "gene_names_uniprotkb": "TESK1", "gene_names_refseq": "TESK1", "protein_names_uniprotkb": "dual-specificity kinase; 2.7.12.1", "protein_names_refseq": "dual specificity testis-specific protein kinase 1 isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100155632); (R-SSC-446388)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0004713 protein tyrosine kinase activity;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0004712 protein serine/threonine/tyrosine kinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005813 centrosome", "go_biological_process": "GO:1902018 negative regulation of cilium assembly;GO:0030036 actin cytoskeleton organization;GO:0051496 positive regulation of stress fiber assembly;GO:1900026 positive regulation of substrate adhesion-dependent cell spreading;GO:0090521 podocyte cell migration", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SG05-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SG86-1", "uniprot_id": "F1SG86_PIG", "mass": 110456.0, "length": 999, "protein_name": "Ephrin type-B receptor 3", "gene_name": "EPHB3", "organism": "Pig", "refseq_name": "ephrin type-B receptor 3 isoform X1", "refseq_ac": "XP_003358781", "gene_names_uniprotkb": "EPHB3", "gene_names_refseq": "EPHB3", "protein_names_uniprotkb": "Ephrin type-B receptor 3; 2.7.10.1", "protein_names_refseq": "ephrin type-B receptor 3 isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100337659); (R-SSC-2682334); (R-SSC-3928662); (R-SSC-3928664); (R-SSC-3928665)", "pathway_count": 5, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0005005 transmembrane-ephrin receptor activity;GO:0008046 axon guidance receptor activity;GO:0005003 ephrin receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0030425 dendrite", "go_biological_process": "GO:0050770 regulation of axonogenesis;GO:0001525 angiogenesis;GO:0016477 cell migration;GO:0048013 ephrin receptor signaling pathway;GO:0022407 regulation of cell-cell adhesion", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SG86-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SGC5-1", "uniprot_id": "F1SGC5_PIG", "mass": 97425.0, "length": 863, "protein_name": "Ubiquitin carboxyl-terminal hydrolase", "gene_name": "USP13", "organism": "Pig", "refseq_name": "ubiquitin carboxyl-terminal hydrolase 13 isoform X1", "refseq_ac": "XP_020926871", "gene_names_uniprotkb": "USP13", "gene_names_refseq": "USP13", "protein_names_uniprotkb": "Ubiquitin carboxyl-terminal hydrolase; 3.4.19.12", "protein_names_refseq": "ubiquitin carboxyl-terminal hydrolase 13 isoform X1", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-5689880); (R-SSC-8948751)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0051087 protein-folding chaperone binding;GO:0031625 ubiquitin protein ligase binding;GO:1904288 BAT3 complex binding;GO:0043130 ubiquitin binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol", "go_biological_process": "GO:0006508 proteolysis;GO:0008283 cell population proliferation;GO:0010506 regulation of autophagy;GO:0070536 protein K63-linked deubiquitination;GO:0006355 regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SGC5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SGQ6-1", "uniprot_id": "F1SGQ6_PIG", "mass": 53959.0, "length": 493, "protein_name": "Receptor-interacting serine/threonine-protein kinase 3", "gene_name": "RIPK3", "organism": "Pig", "refseq_name": "receptor-interacting serine/threonine-protein kinase 3", "refseq_ac": "XP_001927459", "gene_names_uniprotkb": "RIPK3", "gene_names_refseq": "RIPK3", "protein_names_uniprotkb": "Receptor-interacting serine/threonine-protein kinase 3; 2.7.11.1; RIP-like protein kinase 3; Receptor-interacting protein 3", "protein_names_refseq": "receptor-interacting serine/threonine-protein kinase 3", "tax_id": 9823, "disease": "", "pathway": " (ssc:100153263); (R-SSC-2562578); (R-SSC-3295583); (R-SSC-5213460); (R-SSC-5675482); (R-SSC-937041)", "pathway_count": 6, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A4X1SRS7", "ec_number_list": "", "go_molecular_function": "GO:0004672 protein kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0044877 protein-containing complex binding;GO:0120283 protein serine/threonine kinase binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0032991 protein-containing complex", "go_biological_process": "GO:0001914 regulation of T cell mediated cytotoxicity;GO:0007165 signal transduction;GO:0035556 intracellular signal transduction;GO:0051607 defense response to virus;GO:1990000 amyloid fibril formation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SGQ6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SGQ7-1", "uniprot_id": "F1SGQ7_PIG", "mass": 95559.0, "length": 902, "protein_name": "Nuclear factor of activated T-cells, cytoplasmic 1", "gene_name": "NFATC4", "organism": "Pig", "refseq_name": "nuclear factor of activated T-cells, cytoplasmic 4 isoform X2", "refseq_ac": "XP_013833627", "gene_names_uniprotkb": "NFATC4", "gene_names_refseq": "NFATC4", "protein_names_uniprotkb": "Nuclear factor of activated T-cells, cytoplasmic 1; NFAT transcription complex cytosolic component", "protein_names_refseq": "nuclear factor of activated T-cells, cytoplasmic 4 isoform X2", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2 or IL-4 gene transcription. Also controls gene expression in embryonic cardiac cells. Could regulate not only the activation and proliferation but also the differentiation and programmed death of T-lymphocytes as well as lymphoid and non-lymphoid cells. Required for osteoclastogenesis and regulates many genes important for osteoclast differentiation and function., [UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 0, "predicted_o_glycosites": 3, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0016607 nuclear speck;GO:0005667 transcription regulator complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0043524 negative regulation of neuron apoptotic process;GO:0030178 negative regulation of Wnt signaling pathway;GO:0007616 long-term memory", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SGQ7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SGS7-1", "uniprot_id": "F1SGS7_PIG", "mass": 115923.0, "length": 1026, "protein_name": "RNA cytidine acetyltransferase", "gene_name": "NAT10", "organism": "Pig", "refseq_name": "RNA cytidine acetyltransferase", "refseq_ac": "XP_003122923", "gene_names_uniprotkb": "NAT10", "gene_names_refseq": "NAT10", "protein_names_uniprotkb": "RNA cytidine acetyltransferase; 18S rRNA cytosine acetyltransferase; 2.3.1.-; N-acetyltransferase 10", "protein_names_refseq": "RNA cytidine acetyltransferase", "tax_id": 9823, "disease": "", "pathway": " (ssc:100511365)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA-binding adapter protein THUMPD1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0051392 tRNA cytidine N4-acetyltransferase activity;GO:1990883 18S rRNA cytidine N-acetyltransferase activity;GO:0005524 ATP binding;GO:0070182 DNA polymerase binding;GO:0000049 tRNA binding", "go_cellular_component": "GO:0005730 nucleolus;GO:0030496 midbody;GO:0005697 telomerase holoenzyme complex;GO:0032040 small-subunit processome", "go_biological_process": "GO:0010824 regulation of centrosome duplication;GO:0051391 tRNA acetylation;GO:1904812 rRNA acetylation involved in maturation of SSU-rRNA;GO:0032211 negative regulation of telomere maintenance via telomerase;GO:0045727 positive regulation of translation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SGS7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SHP0-1", "uniprot_id": "F1SHP0_PIG", "mass": 101865.0, "length": 929, "protein_name": "A disintegrin and metalloproteinase with thrombospondin motifs 5", "gene_name": "ADAMTS5", "organism": "Pig", "refseq_name": "A disintegrin and metalloproteinase with thrombospondin motifs 5 isoform X1", "refseq_ac": "XP_020926523", "gene_names_uniprotkb": "ADAMTS5", "gene_names_refseq": "ADAMTS5", "protein_names_uniprotkb": "A disintegrin and metalloproteinase with thrombospondin motifs 5; ADMP-2; Aggrecanase-2", "protein_names_refseq": "A disintegrin and metalloproteinase with thrombospondin motifs 5 isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100522952); (R-SSC-1474228); (R-SSC-5173214)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, 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"ec_number_list": "", "go_molecular_function": "GO:0004222 metalloendopeptidase activity;GO:0008201 heparin binding;GO:0008270 zinc ion binding;GO:0042802 identical protein binding;GO:0050840 extracellular matrix binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0031012 extracellular matrix", "go_biological_process": "GO:0006508 proteolysis;GO:0022617 extracellular matrix disassembly;GO:0030198 extracellular matrix organization;GO:0007520 myoblast fusion;GO:0003203 endocardial cushion morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SHP0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SHT0-1", "uniprot_id": "F1SHT0_PIG", "mass": 41363.0, "length": 380, "protein_name": "Homeobox protein Hox-A2", "gene_name": "HOXA2", "organism": "Pig", "refseq_name": "homeobox protein Hox-A2", "refseq_ac": "XP_003134891", "gene_names_uniprotkb": "HOXA2", "gene_names_refseq": "HOXA2", "protein_names_uniprotkb": "Homeobox protein Hox-A2", "protein_names_refseq": "homeobox protein Hox-A2", "tax_id": 9823, "disease": "", "pathway": " (ssc:100519993)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0060037 pharyngeal system development;GO:0048706 embryonic skeletal system development;GO:0061061 muscle structure development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SHT0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SHT7-1", "uniprot_id": "F1SHT7_PIG", "mass": 34833.0, "length": 317, "protein_name": "Homeobox A11", "gene_name": "HOXA11", "organism": "Pig", "refseq_name": "homeobox protein Hox-A11", "refseq_ac": "XP_003134898", "gene_names_uniprotkb": "HOXA11", "gene_names_refseq": "HOXA11", "protein_names_uniprotkb": "Homeobox A11", "protein_names_refseq": "homeobox protein Hox-A11", "tax_id": 9823, "disease": "", "pathway": " (ssc:100521236)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "V9VHL8", "ec_number_list": "", "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005667 transcription regulator complex;GO:0032993 protein-DNA complex", "go_biological_process": "GO:0007501 mesodermal cell fate specification;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0045893 positive regulation of DNA-templated transcription;GO:0060272 embryonic skeletal joint morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SHT7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SHW5-1", "uniprot_id": "F1SHW5_PIG", "mass": 45196.0, "length": 411, "protein_name": "Alanine--glyoxylate aminotransferase", "gene_name": "AGXT", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "AGXT", "gene_names_refseq": "", "protein_names_uniprotkb": "Alanine--glyoxylate aminotransferase; 2.6.1.44; 2.6.1.51; AGT; SPT; Serine--pyruvate aminotransferase", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-389661); (R-SSC-9033241)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004760 L-serine-pyruvate transaminase activity;GO:0030170 pyridoxal phosphate binding;GO:0042803 protein homodimerization activity;GO:0016597 amino acid binding;GO:0008453 alanine-glyoxylate transaminase activity", "go_cellular_component": "GO:0005777 peroxisome;GO:0005782 peroxisomal matrix", "go_biological_process": "GO:0042853 L-alanine catabolic process;GO:0009436 glyoxylate catabolic process;GO:0019265 glycine biosynthetic process, by transamination of glyoxylate;GO:0006563 L-serine metabolic process;GO:0019448 L-cysteine catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SHW5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SI18-1", "uniprot_id": "F1SI18_PIG", "mass": 63725.0, "length": 574, "protein_name": "Frizzled class receptor 7", "gene_name": "FZD7", "organism": "Pig", "refseq_name": "frizzled-7", "refseq_ac": "XP_013839842", "gene_names_uniprotkb": "FZD7", "gene_names_refseq": "FZD7", "protein_names_uniprotkb": "Frizzled class receptor 7", "protein_names_refseq": "frizzled-7", "tax_id": 9823, "disease": "", "pathway": " (ssc:100513691); (R-SSC-4086400); (R-SSC-4608870)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, 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"glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0005109 frizzled binding;GO:0005546 phosphatidylinositol-4,5-bisphosphate binding;GO:0030165 PDZ domain binding;GO:0017147 Wnt-protein binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0055038 recycling endosome membrane", "go_biological_process": "GO:0043410 positive regulation of MAPK cascade;GO:0045893 positive regulation of DNA-templated transcription;GO:0019827 stem cell population maintenance;GO:0042327 positive regulation of phosphorylation;GO:0060070 canonical Wnt signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SI18-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SII9-1", "uniprot_id": "F1SII9_PIG", "mass": 50145.0, "length": 451, "protein_name": "Growth hormone-releasing hormone receptor", "gene_name": "GHRHR", "organism": "Pig", "refseq_name": "growth hormone-releasing hormone receptor isoform X1", "refseq_ac": "XP_020934165", "gene_names_uniprotkb": "GHRHR", "gene_names_refseq": "GHRHR", "protein_names_uniprotkb": "Growth hormone-releasing hormone receptor; Growth hormone-releasing factor receptor", "protein_names_refseq": "growth hormone-releasing hormone receptor isoform X1", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-420092)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Receptor for GRF, coupled to G proteins which activate adenylyl cyclase. Stimulates somatotroph cell growth, growth hormone gene transcription and growth hormone secretion., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0019838 growth factor binding;GO:0017046 peptide hormone binding;GO:0008528 G protein-coupled peptide receptor activity;GO:0016520 growth hormone-releasing hormone receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0009986 cell surface;GO:0030141 secretory granule;GO:0016363 nuclear matrix;GO:0005637 nuclear inner membrane", "go_biological_process": "GO:0007166 cell surface receptor signaling pathway;GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0008284 positive regulation of cell population proliferation;GO:0051384 response to glucocorticoid;GO:0032868 response to insulin", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SII9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SIX5-1", "uniprot_id": "F1SIX5_PIG", "mass": 70399.0, "length": 640, "protein_name": "5-aminolevulinate synthase", "gene_name": "ALAS1", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "ALAS1", "gene_names_refseq": "", "protein_names_uniprotkb": "5-aminolevulinate synthase; 2.3.1.37; 5-aminolevulinic acid synthase; Delta-ALA synthase; Delta-aminolevulinate synthase", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-189451); (R-SSC-9837999)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Catalyzes the pyridoxal 5'-phosphate (PLP)-dependent condensation of succinyl-CoA and glycine to form aminolevulinic acid (ALA), with CoA and CO2 as by-products., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A286ZL81", "ec_number_list": "", "go_molecular_function": "GO:0030170 pyridoxal phosphate binding;GO:0042802 identical protein binding;GO:0003870 5-aminolevulinate synthase activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane;GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0006783 heme biosynthetic process;GO:0006782 protoporphyrinogen IX biosynthetic process;GO:0042541 hemoglobin biosynthetic process;GO:0006784 heme A biosynthetic process;GO:1903412 response to bile acid", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SIX5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SJP0-1", "uniprot_id": "F1SJP0_PIG", "mass": 43812.0, "length": 398, "protein_name": "WW domain containing transcription regulator 1", "gene_name": "WWTR1", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "WWTR1", "gene_names_refseq": "", "protein_names_uniprotkb": "WW domain containing transcription regulator 1", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-2028269); (R-SSC-2032785); (R-SSC-2173796)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003713 transcription coactivator activity;GO:0042803 protein homodimerization activity;GO:0003714 transcription corepressor activity", "go_cellular_component": "GO:0005829 cytosol;GO:0005923 bicellular tight junction;GO:0016604 nuclear body;GO:0005667 transcription regulator complex", "go_biological_process": "GO:0008284 positive regulation of cell population proliferation;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0090090 negative regulation of canonical Wnt signaling pathway;GO:0001894 tissue homeostasis;GO:0035329 hippo signaling", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SJP0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SK05-1", "uniprot_id": "F1SK05_PIG", "mass": 27241.0, "length": 259, "protein_name": "Mesoderm posterior bHLH transcription factor 1", "gene_name": "MESP1", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "MESP1", "gene_names_refseq": "", "protein_names_uniprotkb": "Mesoderm posterior bHLH transcription factor 1", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0046983 protein dimerization activity;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm", "go_biological_process": "GO:0060913 cardiac cell fate determination;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0007219 Notch signaling pathway;GO:0090090 negative regulation of canonical Wnt signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SK05-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SK43-1", "uniprot_id": "F1SK43_PIG", "mass": 32692.0, "length": 300, "protein_name": "Polyisoprenoid diphosphate/phosphate phosphohydrolase PLPP6", "gene_name": "PLPP6", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "PLPP6", "gene_names_refseq": "", "protein_names_uniprotkb": "Polyisoprenoid diphosphate/phosphate phosphohydrolase PLPP6; 3.6.1.68; Phospholipid phosphatase 6", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-9969896)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0052642 lysophosphatidic acid phosphatase activity;GO:0008195 phosphatidate phosphatase activity;GO:0042392 sphingosine-1-phosphate phosphatase activity;GO:0106405 isoprenoid diphosphate phosphatase activity", "go_cellular_component": "GO:0016020 membrane;GO:0005789 endoplasmic reticulum membrane;GO:0005637 nuclear inner membrane", "go_biological_process": "GO:0042632 cholesterol homeostasis;GO:0046839 phospholipid dephosphorylation;GO:1902565 positive regulation of neutrophil activation;GO:0033383 geranyl diphosphate metabolic process;GO:0045339 farnesyl diphosphate catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SK43-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SKD6-1", "uniprot_id": "F1SKD6_PIG", "mass": 54137.0, "length": 494, "protein_name": "Monocarboxylate transporter 2", "gene_name": "SLC16A7", "organism": "Pig", "refseq_name": "monocarboxylate transporter 2", "refseq_ac": "XP_003126385", "gene_names_uniprotkb": "SLC16A7", "gene_names_refseq": "SLC16A7", "protein_names_uniprotkb": "Monocarboxylate transporter 2; Solute carrier family 16 member 7", "protein_names_refseq": "monocarboxylate transporter 2", "tax_id": 9823, "disease": "", "pathway": " (ssc:100158241)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Proton-coupled monocarboxylate symporter. Catalyzes the rapid transport across the plasma membrane of monocarboxylates such as L-lactate, pyruvate and ketone bodies, acetoacetate, beta-hydroxybutyrate and acetate. Dimerization is functionally required and both subunits work cooperatively in transporting substrate., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A4X1W575", "ec_number_list": "", "go_molecular_function": "GO:0042802 identical protein binding;GO:0015293 symporter activity;GO:0050833 pyruvate transmembrane transporter activity;GO:0015129 lactate transmembrane transporter activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0016323 basolateral plasma membrane", "go_biological_process": "GO:0035879 plasma membrane lactate transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SKD6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SL15-1", "uniprot_id": "F1SL15_PIG", "mass": 48297.0, "length": 415, "protein_name": "tRNA methyltransferase 10 homolog C", "gene_name": "TRMT10C", "organism": "Pig", "refseq_name": "mitochondrial ribonuclease P protein 1 isoform X1", "refseq_ac": "XP_005657176", "gene_names_uniprotkb": "TRMT10C", "gene_names_refseq": "TRMT10C", "protein_names_uniprotkb": "tRNA methyltransferase 10 homolog C; 2.1.1.218; 2.1.1.221; Mitochondrial ribonuclease P protein 1; RNA (guanine-9-)-methyltransferase domain-containing protein 1; mRNA methyladenosine-N(1)-methyltransferase; tRNA (adenine(9)-N(1))-methyltransferase; tRNA (guanine(9)-N(1))-methyltransferase", "protein_names_refseq": "mitochondrial ribonuclease P protein 1 isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100522163)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A4X1UZ56", "ec_number_list": "", "go_molecular_function": "GO:0042802 identical protein binding;GO:0000049 tRNA binding;GO:0052905 tRNA (guanosine(9)-N1)-methyltransferase activity;GO:0160106 tRNA (adenine(9)-N1)-methyltransferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005739 mitochondrion;GO:0042645 mitochondrial nucleoid", "go_biological_process": "GO:0006397 mRNA processing;GO:0070131 positive regulation of mitochondrial translation;GO:0070901 mitochondrial tRNA methylation;GO:0001680 tRNA 3'-terminal CCA addition;GO:1990180 mitochondrial tRNA 3'-end processing", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SL15-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SLG7-1", "uniprot_id": "F1SLG7_PIG", "mass": 193648.0, "length": 1795, "protein_name": "Methylcytosine dioxygenase TET", "gene_name": "TET3", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "TET3", "gene_names_refseq": "", "protein_names_uniprotkb": "Methylcytosine dioxygenase TET; 1.14.11.80", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Dioxygenase that catalyzes the conversion of the modified genomic base 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC) and plays a key role in epigenetic chromatin reprogramming during embryonic development., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0008327 methyl-CpG binding;GO:0070579 DNA 5-methylcytosine dioxygenase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0001939 female pronucleus;GO:0005694 chromosome;GO:0001940 male pronucleus", "go_biological_process": "GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0006493 protein O-linked glycosylation;GO:0044727 epigenetic programing of male pronucleus;GO:0141166 chromosomal 5-methylcytosine DNA demethylation pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SLG7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SLM8-1", "uniprot_id": "MCIN_PIG", "mass": 42231.0, "length": 388, "protein_name": "Multicilin", "gene_name": "MCIDAS", "organism": "Pig", "refseq_name": "multicilin", "refseq_ac": "XP_020932711", "gene_names_uniprotkb": "MCIDAS; IDAS; MCIN; MCI", "gene_names_refseq": "MCIDAS", "protein_names_uniprotkb": "Multicilin; McIdas protein; Multiciliate differentiation and DNA synthesis-associated cell cycle protein; Protein Idas", "protein_names_refseq": "multicilin", "tax_id": 9823, "disease": "", "pathway": " (ssc:100737191)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Transcription regulator specifically required for multiciliate cell differentiation. Acts in a multiprotein complex containing E2F4 and E2F5 that binds and activates genes required for centriole biogenesis. Required for the deuterosome-mediated acentriolar pathway. Plays a role in mitotic cell cycle progression by promoting cell cycle exit. Modulates GMNN activity by reducing its affinity for CDT1., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0042802 identical protein binding;GO:0003712 transcription coregulator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0016604 nuclear body", "go_biological_process": "GO:0030174 regulation of DNA-templated DNA replication initiation;GO:1903251 multi-ciliated epithelial cell differentiation;GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0007346 regulation of mitotic cell cycle", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1SLM8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "I3L556-1", "uniprot_id": "I3L556_PIG", "mass": 51043.0, "length": 457, "protein_name": "T-cell surface glycoprotein CD4", "gene_name": "CD4", "organism": "Pig", "refseq_name": "T-cell surface glycoprotein CD4 precursor", "refseq_ac": "NP_001001908", "gene_names_uniprotkb": "CD4", "gene_names_refseq": "CD4", "protein_names_uniprotkb": "T-cell surface glycoprotein CD4; T-cell surface antigen T4/Leu-3", "protein_names_refseq": "T-cell surface glycoprotein CD4 precursor; T-cell surface glycoprotein CD4; lymphocyte antigen CD4", "tax_id": 9823, "disease": "", "pathway": " (ssc:404704); (R-SSC-202424); (R-SSC-202427); (R-SSC-202430); (R-SSC-202433); (R-SSC-389948); (R-SSC-449836); (R-SSC-8856825); (R-SSC-8856828)", "pathway_count": 9, "publication_count": 7, "publication_id_list": "24841667;26429412;29052750;31026568;32543654;33297958;38006719", "class_list": "", "function": "CD4 is an important host factor for Japanese encephalitis virus entry and replication in PK-15 cells., [RefSeq, PubMed]; Results suggest that the SLA-DOB and CD4 genes and their genetic mutations can be considered as important candidate genes and mutations for the immunity of pregnant sows., [RefSeq, PubMed]; The frequency and expression of a CD4 variant in microminipigs are described., [RefSeq, PubMed]; The genetic variability of the T-cell surface glycoprotein CD4 (CD4) gene is associated with immune response-related phenotypes in MeLiM (melanoblastoma-bearing Libechov minipig) strain, which is a model for spontaneous cutaneous melanoma development and regression in minipigs., [RefSeq, PubMed]; These data help clarify the regulatory mechanism of DNA methylation of the CD4 gene in non-immune cell response to virus replication. Publication Status: Online-Only, [RefSeq, PubMed]; Three functional mutation sites affect the immune response of pigs through altering the expression pattern and IgV domain of the CD4 protein. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0015026 coreceptor activity;GO:0005102 signaling receptor binding;GO:0008270 zinc ion binding;GO:0042803 protein homodimerization activity;GO:0023026 MHC class II protein complex binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0009986 cell surface;GO:0045121 membrane raft;GO:0009897 external side of plasma membrane", "go_biological_process": "GO:0007155 cell adhesion;GO:0002250 adaptive immune response;GO:0042110 T cell activation;GO:0050852 T cell receptor signaling pathway;GO:0045657 positive regulation of monocyte differentiation", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "I3L556-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SLW4-1", "uniprot_id": "F1SLW4_PIG", "mass": 27929.0, "length": 236, "protein_name": "C->U-editing enzyme APOBEC-1", "gene_name": "APOBEC1", "organism": "Pig", "refseq_name": "C->U-editing enzyme APOBEC-1 isoform X1", "refseq_ac": "XP_003126567", "gene_names_uniprotkb": "APOBEC1", "gene_names_refseq": "APOBEC1", "protein_names_uniprotkb": "C->U-editing enzyme APOBEC-1; 3.5.4.36; mRNA(cytosine(6666)) deaminase 1", "protein_names_refseq": "C->U-editing enzyme APOBEC-1 isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100512412); (R-SSC-72200); (R-SSC-75094)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Cytidine deaminase catalyzing the cytidine to uridine postranscriptional editing of a variety of mRNAs. Form complexes with cofactors that confer differential editing activity and selectivity. Responsible for the postranscriptional editing of a CAA codon for Gln to a UAA codon for stop in the apolipoprotein B mRNA. Also involved in CGA (Arg) to UGA (Stop) editing in the NF1 mRNA. May also play a role in the epigenetic regulation of gene expression by participating in DNA demethylation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding;GO:0004126 cytidine deaminase activity;GO:0008270 zinc ion binding;GO:0035925 mRNA 3'-UTR AU-rich region binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0030895 apolipoprotein B mRNA editing enzyme complex", "go_biological_process": "GO:0044029 positive regulation of gene expression via chromosomal CpG island demethylation;GO:0006397 mRNA processing;GO:0016554 cytidine to uridine editing;GO:0016556 mRNA modification;GO:2000623 negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SLW4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SNJ6-1", "uniprot_id": "F1SNJ6_PIG", "mass": 116604.0, "length": 1050, "protein_name": "RING-type E3 ubiquitin transferase", "gene_name": "TRIM24", "organism": "Pig", "refseq_name": "transcription intermediary factor 1-alpha isoform X2", "refseq_ac": "XP_020934846", "gene_names_uniprotkb": "TRIM24", "gene_names_refseq": "TRIM24", "protein_names_uniprotkb": "RING-type E3 ubiquitin transferase; 2.3.2.27", "protein_names_refseq": "transcription intermediary factor 1-alpha isoform X2", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0034056 estrogen response element binding;GO:0003682 chromatin binding;GO:0003713 transcription coactivator activity;GO:0004672 protein kinase activity;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005726 perichromatin fibrils;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0000785 chromatin;GO:0000791 euchromatin", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0031647 regulation of protein stability;GO:0016567 protein ubiquitination;GO:0042981 regulation of apoptotic process;GO:0030163 protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SNJ6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SNW8-1", "uniprot_id": "F1SNW8_PIG", "mass": 102362.0, "length": 917, "protein_name": "Hexokinase-2", "gene_name": "HK2", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "HK2", "gene_names_refseq": "", "protein_names_uniprotkb": "Hexokinase-2; 2.7.1.1; Hexokinase type II", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-70171)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Catalyzes the phosphorylation of hexose, such as D-glucose and D-fructose, to hexose 6-phosphate (D-glucose 6-phosphate and D-fructose 6-phosphate, respectively). Mediates the initial step of glycolysis by catalyzing phosphorylation of D-glucose to D-glucose 6-phosphate. Plays a key role in maintaining the integrity of the outer mitochondrial membrane by preventing the release of apoptogenic molecules from the intermembrane space and subsequent apoptosis., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004340 glucokinase activity;GO:0008865 fructokinase activity;GO:0005524 ATP binding;GO:0005536 D-glucose binding", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005741 mitochondrial outer membrane;GO:0005829 cytosol", "go_biological_process": "GO:0035795 negative regulation of mitochondrial membrane permeability;GO:0045766 positive regulation of angiogenesis;GO:2000378 negative regulation of reactive oxygen species metabolic process;GO:0006006 glucose metabolic process;GO:0001678 intracellular glucose homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SNW8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SPK8-1", "uniprot_id": "F1SPK8_PIG", "mass": 25840.0, "length": 237, "protein_name": "Tetraspanin", "gene_name": "CD63", "organism": "Pig", "refseq_name": "CD63 antigen", "refseq_ac": "XP_005663935", "gene_names_uniprotkb": "CD63", "gene_names_refseq": "CD63", "protein_names_uniprotkb": "Tetraspanin", "protein_names_refseq": "CD63 antigen", "tax_id": 9823, "disease": "", "pathway": " (ssc:100155929); (R-SSC-114608); (R-SSC-6798695)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Functions as a cell surface receptor for TIMP1 and plays a role in the activation of cellular signaling cascades. Plays a role in the activation of ITGB1 and integrin signaling, leading to the activation of AKT, FAK/PTK2 and MAP kinases. Promotes cell survival, reorganization of the actin cytoskeleton, cell adhesion, spreading and migration, via its role in the activation of AKT and FAK/PTK2. Plays a role in VEGFA signaling via its role in regulating the internalization of KDR/VEGFR2. Plays a role in intracellular vesicular transport processes, and is required for normal trafficking of the PMEL luminal domain that is essential for the development and maturation of melanocytes. Plays a role in the adhesion of leukocytes onto endothelial cells via its role in the regulation of SELP trafficking. May play a role in mast cell degranulation in response to Ms4a2/FceRI stimulation, but not in mast cell degranulation in response to other stimuli., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A4X1W430", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005886 plasma membrane;GO:0009986 cell surface;GO:0031904 endosome lumen;GO:0070062 extracellular exosome;GO:0005765 lysosomal membrane", "go_biological_process": "GO:0015031 protein transport;GO:0016477 cell migration;GO:0007160 cell-matrix adhesion;GO:0035646 endosome to melanosome transport;GO:0002092 positive regulation of receptor internalization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SPK8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SPV3-1", "uniprot_id": "F1SPV3_PIG", "mass": 52284.0, "length": 472, "protein_name": "Nuclear receptor subfamily 0 group B member 1", "gene_name": "NR0B1", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "NR0B1", "gene_names_refseq": "", "protein_names_uniprotkb": "Nuclear receptor subfamily 0 group B member 1; Nuclear receptor DAX-1", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-383280)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Nuclear receptor that lacks a DNA-binding domain and acts as a corepressor that inhibits the transcriptional activity of other nuclear receptors through heterodimeric interactions. Component of a cascade required for the development of the hypothalamic-pituitary-adrenal-gonadal axis. May also have a role in the development of the embryo and in the maintenance of embryonic stem cell pluripotency., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0032448 DNA hairpin binding;GO:0003723 RNA binding;GO:0019904 protein domain specific binding;GO:0042803 protein homodimerization activity;GO:0003714 transcription corepressor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0016020 membrane;GO:0016607 nuclear speck;GO:0005840 ribosome", "go_biological_process": "GO:0007530 sex determination;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0007283 spermatogenesis;GO:0008584 male gonad development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SPV3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "I3LRN0-1", "uniprot_id": "I3LRN0_PIG", "mass": 82446.0, "length": 737, "protein_name": "E3 ubiquitin-protein ligase", "gene_name": "DTX3L", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "DTX3L", "gene_names_refseq": "", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase; 2.3.2.27", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-983168)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity;GO:0097677 STAT family protein binding;GO:0004857 enzyme inhibitor activity;GO:0042393 histone binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005654 nucleoplasm;GO:0005769 early endosome;GO:0005829 cytosol;GO:0005764 lysosome", "go_biological_process": "GO:0007219 Notch signaling pathway;GO:0016567 protein ubiquitination;GO:1902966 positive regulation of protein localization to early endosome;GO:2000646 positive regulation of receptor catabolic process;GO:0045893 positive regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "I3LRN0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SQC3-1", "uniprot_id": "F1SQC3_PIG", "mass": 19253.0, "length": 166, "protein_name": "von Hippel-Lindau disease tumor suppressor", "gene_name": "VHL", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "VHL", "gene_names_refseq": "", "protein_names_uniprotkb": "von Hippel-Lindau disease tumor suppressor; pVHL", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Involved in the ubiquitination and subsequent proteasomal degradation via the von Hippel-Lindau ubiquitination complex. Seems to act as a target recruitment subunit in the E3 ubiquitin ligase complex and recruits hydroxylated hypoxia-inducible factor (HIF) under normoxic conditions. Involved in transcriptional repression through interaction with HIF1A, HIF1AN and histone deacetylases. Ubiquitinates, in an oxygen-responsive manner, ADRB2. Acts as a negative regulator of mTORC1 by promoting ubiquitination and degradation of RPTOR., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0044877 protein-containing complex binding", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005783 endoplasmic reticulum;GO:0005886 plasma membrane", "go_biological_process": "GO:0001666 response to hypoxia;GO:0010468 regulation of gene expression;GO:0099175 regulation of postsynapse organization;GO:0140252 regulation protein catabolic process at postsynapse", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SQC3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SQF7-1", "uniprot_id": "F1SQF7_PIG", "mass": 48934.0, "length": 432, "protein_name": "Transcriptional adapter 3", "gene_name": "TADA3", "organism": "Pig", "refseq_name": "transcriptional adapter 3", "refseq_ac": "NP_001193465", "gene_names_uniprotkb": "TADA3", "gene_names_refseq": "TADA3", "protein_names_uniprotkb": "Transcriptional adapter 3; ADA3 homolog; Transcriptional adapter 3-like", "protein_names_refseq": "transcriptional adapter 3", "tax_id": 9823, "disease": "", "pathway": " (ssc:100157464); (R-SSC-5689880)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Functions as a component of the PCAF complex. The PCAF complex is capable of efficiently acetylating histones in a nucleosomal context. The PCAF complex could be considered as the human version of the yeast SAGA complex. Also known as a coactivator for p53/TP53-dependent transcriptional activation. Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A4X1UWQ3", "ec_number_list": "", "go_molecular_function": "GO:0003713 transcription coactivator activity;GO:0019904 protein domain specific binding;GO:0016922 nuclear receptor binding", "go_cellular_component": "GO:0033276 transcription factor TFTC complex;GO:0000124 SAGA complex;GO:0072686 mitotic spindle;GO:0140672 ATAC complex", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0010628 positive regulation of gene expression;GO:0051726 regulation of cell cycle", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SQF7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P00336-1", "uniprot_id": "LDHB_PIG", "mass": 36612.0, "length": 334, "protein_name": "L-lactate dehydrogenase B chain", "gene_name": "LDHB", "organism": "Pig", "refseq_name": "L-lactate dehydrogenase B chain", "refseq_ac": "NP_001106758", "gene_names_uniprotkb": "LDHB", "gene_names_refseq": "LDH-B; LDH-H; LDHB", "protein_names_uniprotkb": "L-lactate dehydrogenase B chain; 1.1.1.27; LDH heart subunit; LDH-B; LDH-H", "protein_names_refseq": "L-lactate dehydrogenase B chain; LDH heart subunit", "tax_id": 9823, "disease": "", "pathway": " (ssc:100621540); (ssc:102161427)", "pathway_count": 2, "publication_count": 5, "publication_id_list": "17334683;32543654;7338899;7937776;838465", "class_list": "", "function": "Interconverts simultaneously and stereospecifically pyruvate and lactate with concomitant interconversion of NADH and NAD(+)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; The NADH-cofactor binding site of pig heart LDH is involved in the interaction with acidic phospholipids, in the pig skeletal muscle LDH, neither the cofactor binding site nor the subunit interfacing areas seem to be involved in the interaction., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004459 L-lactate dehydrogenase (NAD+) activity", "go_cellular_component": "GO:0005743 mitochondrial inner membrane;GO:0005737 cytoplasm", "go_biological_process": "GO:0019752 carboxylic acid metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P00336-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SRW1-1", "uniprot_id": "F1SRW1_PIG", "mass": 108772.0, "length": 982, "protein_name": "Ephrin type-A receptor 1", "gene_name": "EPHA1", "organism": "Pig", "refseq_name": "ephrin type-A receptor 1", "refseq_ac": "XP_003134614", "gene_names_uniprotkb": "EPHA1", "gene_names_refseq": "EPHA1", "protein_names_uniprotkb": "Ephrin type-A receptor 1; 2.7.10.1", "protein_names_refseq": "ephrin type-A receptor 1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100519989); (R-SSC-2682334); (R-SSC-3928663); (R-SSC-3928665)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Receptor tyrosine kinase which binds promiscuously membrane-bound ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Binds with a low affinity EFNA3 and EFNA4 and with a high affinity to EFNA1 which most probably constitutes its cognate/functional ligand. Upon activation by EFNA1 induces cell attachment to the extracellular matrix inhibiting cell spreading and motility through regulation of ILK and downstream RHOA and RAC. Also plays a role in angiogenesis and regulates cell proliferation. May play a role in apoptosis., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0019901 protein kinase binding;GO:0004714 transmembrane receptor protein tyrosine kinase activity;GO:0001968 fibronectin binding;GO:0005005 transmembrane-ephrin receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0043235 receptor complex", "go_biological_process": "GO:0001525 angiogenesis;GO:0007169 cell surface receptor protein tyrosine kinase signaling pathway;GO:0030335 positive regulation of cell migration;GO:0030336 negative regulation of cell migration;GO:0045766 positive regulation of angiogenesis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SRW1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SRY5-1", "uniprot_id": "UBP37_PIG", "mass": 110483.0, "length": 982, "protein_name": "Ubiquitin carboxyl-terminal hydrolase 37", "gene_name": "USP37", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "USP37", "gene_names_refseq": "", "protein_names_uniprotkb": "Ubiquitin carboxyl-terminal hydrolase 37; 3.4.19.12; Deubiquitinating enzyme 37; Ubiquitin thioesterase 37; Ubiquitin-specific-processing protease 37", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Deubiquitinase that plays a role in different processes including cell cycle regulation, DNA replication or DNA damage response. Antagonizes the anaphase-promoting complex (APC/C) during G1/S transition by mediating deubiquitination of cyclin-A (CCNA1 and CCNA2), thereby promoting S phase entry. Specifically mediates deubiquitination of 'Lys-11'-linked polyubiquitin chains, a specific ubiquitin-linkage type mediated by the APC/C complex. Phosphorylation at Ser-628 during G1/S phase maximizes the deubiquitinase activity, leading to prevent degradation of cyclin-A (CCNA1 and CCNA2). Plays an important role in the regulation of DNA replication by stabilizing the licensing factor CDT1. Also plays an essential role beyond S-phase entry to promote the efficiency and fidelity of replication by deubiquitinating checkpoint kinase 1/CHK1, promoting its stability. Sustains the DNA damage response (DDR) by deubiquitinating and stabilizing the ATP-dependent DNA helicase BLM. Mechanistically, DNA double-strand breaks (DSB) promotes ATM-mediated phosphorylation of USP37 and enhances the binding between USP37 and BLM. Promotes cell migration by deubiquitinating and stabilizing the epithelial-mesenchymal transition (EMT)-inducing transcription factor SNAI. Plays a role in the regulation of mitotic spindle assembly and mitotic progression by associating with chromatin-associated WAPL and stabilizing it through deubiquitination., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 7, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004197 cysteine-type endopeptidase activity;GO:0004843 cysteine-type deubiquitinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol;GO:0005694 chromosome", "go_biological_process": "GO:0006508 proteolysis;GO:0016579 protein deubiquitination;GO:0051301 cell division;GO:0031647 regulation of protein stability;GO:0000082 G1/S transition of mitotic cell cycle", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "F1SRY5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SSN7-1", "uniprot_id": "F1SSN7_PIG", "mass": 55452.0, "length": 492, "protein_name": "Autophagy related 14", "gene_name": "ATG14", "organism": "Pig", "refseq_name": "beclin 1-associated autophagy-related key regulator", "refseq_ac": "XP_001925025", "gene_names_uniprotkb": "ATG14", "gene_names_refseq": "ATG14", "protein_names_uniprotkb": "Autophagy related 14", "protein_names_refseq": "beclin 1-associated autophagy-related key regulator", "tax_id": 9823, "disease": "", "pathway": " (ssc:100155666); (R-SSC-1632852)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0051020 GTPase binding;GO:0043495 protein-membrane adaptor activity;GO:0035014 phosphatidylinositol 3-kinase regulator activity;GO:0141039 phosphatidylinositol 3-kinase inhibitor activity", "go_cellular_component": "GO:0044233 mitochondria-associated endoplasmic reticulum membrane contact site;GO:0045335 phagocytic vesicle;GO:0005776 autophagosome;GO:0005930 axoneme;GO:0035032 phosphatidylinositol 3-kinase complex, class III", "go_biological_process": "GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process;GO:0000045 autophagosome assembly;GO:0010608 post-transcriptional regulation of gene expression;GO:0016241 regulation of macroautophagy;GO:0045022 early endosome to late endosome transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SSN7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SSU6-1", "uniprot_id": "F1SSU6_PIG", "mass": 110142.0, "length": 973, "protein_name": "Vacuolar protein sorting-associated protein 18 homolog", "gene_name": "VPS18", "organism": "Pig", "refseq_name": "vacuolar protein sorting-associated protein 18 homolog isoform X1", "refseq_ac": "XP_001929396", "gene_names_uniprotkb": "VPS18", "gene_names_refseq": "VPS18", "protein_names_uniprotkb": "Vacuolar protein sorting-associated protein 18 homolog", "protein_names_refseq": "vacuolar protein sorting-associated protein 18 homolog isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100153351)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003779 actin binding;GO:0008270 zinc ion binding;GO:0030674 protein-macromolecule adaptor activity;GO:0019905 syntaxin binding;GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0030897 HOPS complex;GO:0005768 endosome;GO:0005769 early endosome;GO:0005884 actin filament", "go_biological_process": "GO:0048284 organelle fusion;GO:0006886 intracellular protein transport;GO:0007032 endosome organization;GO:0007040 lysosome organization;GO:0008333 endosome to lysosome transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SSU6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1ST77-1", "uniprot_id": "F1ST77_PIG", "mass": 123591.0, "length": 1128, "protein_name": "Adenylate cyclase type 1", "gene_name": "ADCY1", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "ADCY1", "gene_names_refseq": "", "protein_names_uniprotkb": "Adenylate cyclase type 1; 4.6.1.1", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-163615); (R-SSC-170660); (R-SSC-170670); (R-SSC-418597); (R-SSC-5610787)", "pathway_count": 5, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004016 adenylate cyclase activity;GO:0005524 ATP binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0098978 glutamatergic synapse;GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0098793 presynapse;GO:0098839 postsynaptic density membrane", "go_biological_process": "GO:0006171 cAMP biosynthetic process;GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0035556 intracellular signal transduction;GO:1900273 positive regulation of long-term synaptic potentiation;GO:0042752 regulation of circadian rhythm", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1ST77-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1STB6-1", "uniprot_id": "F1STB6_PIG", "mass": 103052.0, "length": 915, "protein_name": "Non-lysosomal glucosylceramidase", "gene_name": "GBA2", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "GBA2", "gene_names_refseq": "", "protein_names_uniprotkb": "Non-lysosomal glucosylceramidase; 3.2.1.45; NLGase", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-9840310)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Non-lysosomal glucosylceramidase that catalyzes the hydrolysis of glucosylceramide (GlcCer) to free glucose and ceramide., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004348 glucosylceramidase activity;GO:0008422 beta-glucosidase activity;GO:0046527 glucosyltransferase activity;GO:0004336 galactosylceramidase activity;GO:0050295 steryl-beta-glucosidase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005829 cytosol;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006680 glucosylceramide catabolic process;GO:0008203 cholesterol metabolic process;GO:0005975 carbohydrate metabolic process;GO:0007417 central nervous system development;GO:0009247 glycolipid biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1STB6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1STP7-1", "uniprot_id": "F1STP7_PIG", "mass": 35211.0, "length": 330, "protein_name": "G protein-coupled receptor 3", "gene_name": "GPR3", "organism": "Pig", "refseq_name": "G-protein coupled receptor 3", "refseq_ac": "NP_001244154", "gene_names_uniprotkb": "GPR3", "gene_names_refseq": "GPR3", "protein_names_uniprotkb": "G protein-coupled receptor 3", "protein_names_refseq": "G-protein coupled receptor 3", "tax_id": 9823, "disease": "", "pathway": " (ssc:100512611)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "22207171;22498817;22685609;32543654", "class_list": "", "function": "A gene encoding Gpr3 from pigs was cloned and its expression pattern in tissues and the whole cumulus-oocyte complexes (COCs) in vitro maturation (IVM), was investigated., [RefSeq, PubMed]; Data suggest that G protein coupled receptor 3 (GPR3) is required for maintenance of meiotic arrest in porcine oocytes through pathways involved in the regulation of cAMP and cGMP., [RefSeq, PubMed]; Stage- and cell-specific expression patterns during embryonic and developmental growth of ovaries suggest that GPR3 plays important roles during follicular development, luteinization, and regulation of expression of cell cycle proteins., [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A4X1UBB1", "ec_number_list": "", "go_molecular_function": "GO:0038036 sphingosine-1-phosphate receptor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0031965 nuclear membrane", "go_biological_process": "GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007204 positive regulation of cytosolic calcium ion concentration;GO:0008285 negative regulation of cell population proliferation;GO:0007199 G protein-coupled receptor signaling pathway coupled to cGMP nucleotide second messenger;GO:1900194 negative regulation of oocyte maturation", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "F1STP7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1STZ5-1", "uniprot_id": "F1STZ5_PIG", "mass": 110925.0, "length": 1004, "protein_name": "Ephrin type-A receptor 8", "gene_name": "EPHA8", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "EPHA8", "gene_names_refseq": "", "protein_names_uniprotkb": "Ephrin type-A receptor 8; 2.7.10.1; EPH- and ELK-related kinase; Tyrosine-protein kinase receptor EEK", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. The GPI-anchored ephrin-A EFNA2, EFNA3, and EFNA5 are able to activate EPHA8 through phosphorylation. With EFNA5 may regulate integrin-mediated cell adhesion and migration on fibronectin substrate but also neurite outgrowth. During development of the nervous system also plays a role in axon guidance. Downstream effectors of the EPHA8 signaling pathway include FYN which promotes cell adhesion upon activation by EPHA8 and the MAP kinases in the stimulation of neurite outgrowth., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0019838 growth factor binding;GO:0004714 transmembrane receptor protein tyrosine kinase activity;GO:0005004 GPI-linked ephrin receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0043235 receptor complex;GO:0031901 early endosome membrane;GO:0043005 neuron projection", "go_biological_process": "GO:0033628 regulation of cell adhesion mediated by integrin;GO:0007155 cell adhesion;GO:0007169 cell surface receptor protein tyrosine kinase signaling pathway;GO:0016322 neuron remodeling;GO:0043410 positive regulation of MAPK cascade", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1STZ5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SUG1-1", "uniprot_id": "F1SUG1_PIG", "mass": 83134.0, "length": 740, "protein_name": "ATP-dependent RNA helicase SUPV3L1, mitochondrial", "gene_name": "SUPV3L1", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "SUPV3L1", "gene_names_refseq": "", "protein_names_uniprotkb": "ATP-dependent RNA helicase SUPV3L1, mitochondrial; 3.6.4.13; Suppressor of var1 3-like protein 1", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Major helicase player in mitochondrial RNA metabolism. Component of the mitochondrial degradosome (mtEXO) complex, that degrades 3' overhang double-stranded RNA with a 3'-to-5' directionality in an ATP-dependent manner. Involved in the degradation of non-coding mitochondrial transcripts (MT-ncRNA) and tRNA-like molecules. ATPase and ATP-dependent multisubstrate helicase, able to unwind double-stranded (ds) DNA and RNA, and RNA/DNA heteroduplexes in the 5'-to-3' direction. Plays a role in the RNA surveillance system in mitochondria; regulates the stability of mature mRNAs, the removal of aberrantly formed mRNAs and the rapid degradation of non coding processing intermediates. Also implicated in recombination and chromatin maintenance pathways. May protect cells from apoptosis. Associates with mitochondrial DNA., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0005524 ATP binding;GO:0042803 protein homodimerization activity;GO:0003725 double-stranded RNA binding;GO:0003678 DNA helicase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0042645 mitochondrial nucleoid;GO:0045025 mitochondrial degradosome", "go_biological_process": "GO:0006310 DNA recombination;GO:0030307 positive regulation of cell growth;GO:0043066 negative regulation of apoptotic process;GO:0007005 mitochondrion organization;GO:0000962 positive regulation of mitochondrial RNA catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SUG1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SUG7-1", "uniprot_id": "F1SUG7_PIG", "mass": 87194.0, "length": 784, "protein_name": "Nucleolar RNA helicase 2", "gene_name": "DDX21", "organism": "Pig", "refseq_name": "nucleolar RNA helicase 2", "refseq_ac": "XP_005657444", "gene_names_uniprotkb": "DDX21", "gene_names_refseq": "DDX21", "protein_names_uniprotkb": "Nucleolar RNA helicase 2; 3.6.4.13; DEAD box protein 21; Gu-alpha; Nucleolar RNA helicase Gu; Nucleolar RNA helicase II; RH II/Gu", "protein_names_refseq": "nucleolar RNA helicase 2", "tax_id": 9823, "disease": "", "pathway": " (ssc:100153111); (R-SSC-5250924); (R-SSC-6791226)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "K9IVG8", "ec_number_list": "", "go_molecular_function": "GO:0003729 mRNA binding;GO:0005524 ATP binding;GO:0016787 hydrolase activity;GO:0042802 identical protein binding;GO:0030515 snoRNA binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005739 mitochondrion;GO:0005829 cytosol;GO:0005694 chromosome", "go_biological_process": "GO:0045087 innate immune response;GO:0051607 defense response to virus;GO:0043123 positive regulation of canonical NF-kappaB signal transduction;GO:0006366 transcription by RNA polymerase II;GO:0045945 positive regulation of transcription by RNA polymerase III", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SUG7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SUI6-1", "uniprot_id": "F1SUI6_PIG", "mass": 118071.0, "length": 1045, "protein_name": "DNA replication ATP-dependent helicase/nuclease", "gene_name": "DNA2", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "DNA2", "gene_names_refseq": "", "protein_names_uniprotkb": "DNA replication ATP-dependent helicase/nuclease; 3.1.-.-; 3.6.4.12", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-174437); (R-SSC-5685938); (R-SSC-5685942); (R-SSC-5693537); (R-SSC-5693568); (R-SSC-5693579); (R-SSC-5693607); (R-SSC-5693616); (R-SSC-6804756); (R-SSC-69166); (R-SSC-69473)", "pathway_count": 11, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Key enzyme involved in DNA replication and DNA repair. Involved in Okazaki fragments processing by cleaving long flaps that escape FEN1: flaps that are longer than 27 nucleotides are coated by replication protein A complex (RPA), leading to recruit DNA2 which cleaves the flap until it is too short to bind RPA and becomes a substrate for FEN1. Also involved in 5'-end resection of DNA during double-strand break (DSB) repair by mediating the cleavage of 5'-ssDNA., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0003723 RNA binding;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0051539 4 iron, 4 sulfur cluster binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0042645 mitochondrial nucleoid;GO:0000781 chromosome, telomeric region", "go_biological_process": "GO:0000076 DNA replication checkpoint signaling;GO:0006284 base-excision repair;GO:0045740 positive regulation of DNA replication;GO:0000729 DNA double-strand break processing;GO:0006264 mitochondrial DNA replication", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SUI6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SUR9-1", "uniprot_id": "F1SUR9_PIG", "mass": 128575.0, "length": 1178, "protein_name": "Polyamine-transporting ATPase 13A2", "gene_name": "ATP13A2", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "ATP13A2", "gene_names_refseq": "", "protein_names_uniprotkb": "Polyamine-transporting ATPase 13A2", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-936837)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "ATPase which acts as a lysosomal polyamine exporter with high affinity for spermine. Also stimulates cellular uptake of polyamines and protects against polyamine toxicity. Plays a role in intracellular cation homeostasis and the maintenance of neuronal integrity. Contributes to cellular zinc homeostasis. Confers cellular protection against Mn(2+) and Zn(2+) toxicity and mitochondrial stress. Required for proper lysosomal and mitochondrial maintenance. Regulates the autophagy-lysosome pathway through the control of SYT11 expression at both transcriptional and post-translational levels. Facilitates recruitment of deacetylase HDAC6 to lysosomes to deacetylate CTTN, leading to actin polymerization, promotion of autophagosome-lysosome fusion and completion of autophagy. Promotes secretion of exosomes as well as secretion of SCNA via exosomes. Plays a role in lipid homeostasis., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0016887 ATP hydrolysis activity;GO:0080025 phosphatidylinositol-3,5-bisphosphate binding;GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity", "go_cellular_component": "GO:0000421 autophagosome membrane;GO:0043025 neuronal cell body;GO:0005765 lysosomal membrane;GO:0031902 late endosome membrane;GO:0043005 neuron projection", "go_biological_process": "GO:1903710 spermine transmembrane transport;GO:0010628 positive regulation of gene expression;GO:0055088 lipid homeostasis;GO:0006874 intracellular calcium ion homeostasis;GO:0006879 intracellular iron ion homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SUR9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SUY1-1", "uniprot_id": "F1SUY1_PIG", "mass": 16632.0, "length": 159, "protein_name": "Podoplanin", "gene_name": "PDPN", "organism": "Pig", "refseq_name": "podoplanin", "refseq_ac": "XP_005665074", "gene_names_uniprotkb": "PDPN", "gene_names_refseq": "PDPN", "protein_names_uniprotkb": "Podoplanin", "protein_names_refseq": "podoplanin", "tax_id": 9823, "disease": "", "pathway": " (ssc:100738269); (R-SSC-114604)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005102 signaling receptor binding;GO:0051087 protein-folding chaperone binding;GO:0019956 chemokine binding", "go_cellular_component": "GO:0061851 leading edge of lamellipodium;GO:0005829 cytosol;GO:0016323 basolateral plasma membrane;GO:0030027 lamellipodium;GO:0030054 cell junction", "go_biological_process": "GO:0007155 cell adhesion;GO:0007165 signal transduction;GO:0016477 cell migration;GO:0030335 positive regulation of cell migration;GO:0007266 Rho protein signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SUY1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SV56-1", "uniprot_id": "F1SV56_PIG", "mass": 53696.0, "length": 470, "protein_name": "Collagenase 3", "gene_name": "MMP13", "organism": "Pig", "refseq_name": "collagenase 3 isoform X1", "refseq_ac": "XP_003129856", "gene_names_uniprotkb": "MMP13", "gene_names_refseq": "MMP13", "protein_names_uniprotkb": "Collagenase 3; Matrix metalloproteinase-13", "protein_names_refseq": "collagenase 3 isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:397346); (R-SSC-1442490); (R-SSC-1474228); (R-SSC-1592389)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Plays a role in the degradation of extracellular matrix proteins including fibrillar collagen, fibronectin, TNC and ACAN. Cleaves triple helical collagens, including type I, type II and type III collagen, but has the highest activity with soluble type II collagen. Can also degrade collagen type IV, type XIV and type X. May also function by activating or degrading key regulatory proteins, such as TGFB1 and CCN2. Plays a role in wound healing, tissue remodeling, cartilage degradation, bone development, bone mineralization and ossification. Required for normal embryonic bone development and ossification. Plays a role in the healing of bone fractures via endochondral ossification. Plays a role in wound healing, probably by a mechanism that involves proteolytic activation of TGFB1 and degradation of CCN2. Plays a role in keratinocyte migration during wound healing. May play a role in cell migration and in tumor cell invasion., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004222 metalloendopeptidase activity;GO:0008270 zinc ion binding;GO:0005509 calcium ion binding;GO:0005518 collagen binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0031012 extracellular matrix", "go_biological_process": "GO:0006508 proteolysis;GO:0022617 extracellular matrix disassembly;GO:0030198 extracellular matrix organization;GO:0030574 collagen catabolic process;GO:0030282 bone mineralization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SV56-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SV58-1", "uniprot_id": "F1SV58_PIG", "mass": 54083.0, "length": 477, "protein_name": "Stromelysin-1", "gene_name": "MMP3", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "MMP3", "gene_names_refseq": "", "protein_names_uniprotkb": "Stromelysin-1; 3.4.24.17; Matrix metalloproteinase-3", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-1442490); (R-SSC-1474228); (R-SSC-1592389); (R-SSC-2179392); (R-SSC-9009391)", "pathway_count": 5, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004222 metalloendopeptidase activity;GO:0008270 zinc ion binding", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005829 cytosol;GO:0031012 extracellular matrix", "go_biological_process": "GO:0006508 proteolysis;GO:0030198 extracellular matrix organization;GO:0045087 innate immune response;GO:0031334 positive regulation of protein-containing complex assembly;GO:2000378 negative regulation of reactive oxygen species metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SV58-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F2Z5P4-1", "uniprot_id": "F2Z5P4_PIG", "mass": 23548.0, "length": 200, "protein_name": "Sorting nexin 10", "gene_name": "SNX10", "organism": "Pig", "refseq_name": "sorting nexin-10", "refseq_ac": "XP_003134896", "gene_names_uniprotkb": "SNX10", "gene_names_refseq": "SNX10", "protein_names_uniprotkb": "Sorting nexin 10", "protein_names_refseq": "sorting nexin-10", "tax_id": 9823, "disease": "", "pathway": " (ssc:100520876)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A4X1TTL3", "ec_number_list": "", "go_molecular_function": "GO:0051117 ATPase binding;GO:0005545 1-phosphatidylinositol binding;GO:1901981 phosphatidylinositol phosphate binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005768 endosome;GO:0005783 endoplasmic reticulum;GO:0005813 centrosome;GO:0005829 cytosol", "go_biological_process": "GO:0030316 osteoclast differentiation;GO:0006886 intracellular protein transport;GO:0007032 endosome organization;GO:0060271 cilium assembly;GO:0016050 vesicle organization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F2Z5P4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F2Z5Q5-1", "uniprot_id": "F2Z5Q5_PIG", "mass": 36566.0, "length": 313, "protein_name": "Ras-related GTP-binding protein", "gene_name": "RRAGA", "organism": "Pig", "refseq_name": "ras-related GTP-binding protein A", "refseq_ac": "XP_005660144", "gene_names_uniprotkb": "RRAGA", "gene_names_refseq": "RRAGA", "protein_names_uniprotkb": "Ras-related GTP-binding protein", "protein_names_refseq": "ras-related GTP-binding protein A", "tax_id": 9823, "disease": "", "pathway": " (ssc:100153321); (R-SSC-1632852); (R-SSC-165159); (R-SSC-166208); (R-SSC-380972); (R-SSC-5628897); (R-SSC-8866654); (R-SSC-8943724); (R-SSC-9639288)", "pathway_count": 9, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0042803 protein homodimerization activity;GO:0046982 protein heterodimerization activity;GO:0031625 ubiquitin protein ligase binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005764 lysosome;GO:0005765 lysosomal membrane;GO:1990130 GATOR1 complex", "go_biological_process": "GO:1904263 positive regulation of TORC1 signaling;GO:0035556 intracellular signal transduction;GO:0042593 glucose homeostasis;GO:0010507 negative regulation of autophagy;GO:0072657 protein localization to membrane", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F2Z5Q5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F2Z5V0-1", "uniprot_id": "F2Z5V0_PIG", "mass": 55210.0, "length": 505, "protein_name": "RNA-splicing ligase RtcB homolog", "gene_name": "RTCB", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "RTCB", "gene_names_refseq": "", "protein_names_uniprotkb": "RNA-splicing ligase RtcB homolog; 3'-phosphate/5'-hydroxy nucleic acid ligase; 6.5.1.8", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005525 GTP binding;GO:0046872 metal ion binding;GO:0017166 vinculin binding;GO:0044600 protein guanylyltransferase activity;GO:0170057 RNA ligase (GTP) activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005635 nuclear envelope;GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0070054 mRNA splicing, via endonucleolytic cleavage and ligation;GO:0036498 IRE1-mediated unfolded protein response;GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation;GO:0000968 tRNA exon ligation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F2Z5V0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F6PXC7-1", "uniprot_id": "F6PXC7_PIG", "mass": 208077.0, "length": 1993, "protein_name": "Neurogenic locus notch homolog protein 4", "gene_name": "NOTCH4", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "NOTCH4", "gene_names_refseq": "", "protein_names_uniprotkb": "Neurogenic locus notch homolog protein 4", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-1912420); (R-SSC-350054); (R-SSC-9013700)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. May regulate branching morphogenesis in the developing vascular system., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003713 transcription coactivator activity;GO:0005509 calcium ion binding;GO:0005112 Notch binding;GO:0038023 signaling receptor activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005783 endoplasmic reticulum;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0009986 cell surface", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0007219 Notch signaling pathway;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0001837 epithelial to mesenchymal transition", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F6PXC7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F6Q4L6-1", "uniprot_id": "F6Q4L6_PIG", "mass": 67133.0, "length": 615, "protein_name": "Mitochondrial adenyl nucleotide antiporter SLC25A24", "gene_name": "SLC25A24", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "SLC25A24", "gene_names_refseq": "", "protein_names_uniprotkb": "Mitochondrial adenyl nucleotide antiporter SLC25A24; Solute carrier family 25 member 24", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Electroneutral antiporter that mediates the transport of adenyl nucleotides through the inner mitochondrial membrane. Originally identified as an ATP-magnesium/inorganic phosphate antiporter, it also acts as a broad specificity adenyl nucleotide antiporter. By regulating the mitochondrial matrix adenyl nucleotide pool, could adapt to changing cellular energetic demands and indirectly regulate adenyl nucleotide-dependent metabolic pathways. In vitro, a low activity is also observed with guanyl and pyrimidine nucleotides. May play a role in protecting cells against oxidative stress-induced cell death, by buffering calcium levels in the mitochondrial matrix through the formation of calcium-phosphate precipitates., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005509 calcium ion binding;GO:0005347 ATP transmembrane transporter activity;GO:0140987 ATP:phosphate antiporter activity;GO:0140988 ADP:phosphate antiporter activity", "go_cellular_component": "GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0006839 mitochondrial transport;GO:0071277 cellular response to calcium ion;GO:0034599 cellular response to oxidative stress;GO:0015866 ADP transport;GO:0015867 ATP transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F6Q4L6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F6QA08-1", "uniprot_id": "F6QA08_PIG", "mass": 56730.0, "length": 504, "protein_name": "Protein disulfide-isomerase", "gene_name": "PDIA3", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "PDIA3", "gene_names_refseq": "", "protein_names_uniprotkb": "Protein disulfide-isomerase; 5.3.4.1", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-1236974); (R-SSC-901042); (R-SSC-983170)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Protein disulfide isomerase that catalyzes the formation, isomerization, and reduction or oxidation of disulfide bonds in client proteins and functions as a protein folding chaperone. Core component of the major histocompatibility complex class I (MHC I) peptide loading complex where it functions as an essential folding chaperone for TAPBP. Through TAPBP, assists the dynamic assembly of the MHC I complex with high affinity antigens in the endoplasmic reticulum. Therefore, plays a crucial role in the presentation of antigens to cytotoxic T cells in adaptive immunity., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0042802 identical protein binding;GO:0015035 protein-disulfide reductase activity;GO:0003756 protein disulfide isomerase activity;GO:0044183 protein folding chaperone;GO:0106222 lncRNA binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005783 endoplasmic reticulum;GO:0005788 endoplasmic reticulum lumen;GO:0009986 cell surface;GO:0042470 melanosome", "go_biological_process": "GO:0006457 protein folding;GO:0034976 response to endoplasmic reticulum stress;GO:0002502 peptide antigen assembly with MHC class I protein complex", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F6QA08-1", "record_type": "protein" }, { "uniprot_canonical_ac": "I3L5L7-1", "uniprot_id": "I3L5L7_PIG", "mass": 43033.0, "length": 408, "protein_name": "POU domain protein", "gene_name": "POU4F2", "organism": "Pig", "refseq_name": "POU domain, class 4, transcription factor 2", "refseq_ac": "XP_003482480", "gene_names_uniprotkb": "POU4F2", "gene_names_refseq": "POU4F2", "protein_names_uniprotkb": "POU domain protein", "protein_names_refseq": "POU domain, class 4, transcription factor 2", "tax_id": 9823, "disease": "", "pathway": " (ssc:100522504); (R-SSC-6804759)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific;GO:0002039 p53 binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0016607 nuclear speck;GO:0005667 transcription regulator complex;GO:0000791 euchromatin", "go_biological_process": "GO:1902870 negative regulation of amacrine cell differentiation;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0007507 heart development;GO:0032869 cellular response to insulin stimulus", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "I3L5L7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "I3L5S1-1", "uniprot_id": "I3L5S1_PIG", "mass": 64572.0, "length": 549, "protein_name": "O-acyltransferase", "gene_name": "SOAT1", "organism": "Pig", "refseq_name": "sterol O-acyltransferase 1", "refseq_ac": "XP_003357604", "gene_names_uniprotkb": "SOAT1", "gene_names_refseq": "SOAT1", "protein_names_uniprotkb": "O-acyltransferase", "protein_names_refseq": "sterol O-acyltransferase 1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100628166); (R-SSC-8964038)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A8D0XBF5", "ec_number_list": "", "go_molecular_function": "GO:0015485 cholesterol binding;GO:0000062 fatty-acyl-CoA binding;GO:0034736 cholesterol O-acyltransferase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0010742 macrophage derived foam cell differentiation;GO:0008203 cholesterol metabolic process;GO:0033344 cholesterol efflux;GO:0034379 very-low-density lipoprotein particle assembly;GO:0042632 cholesterol homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "I3L5S1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "I3L7E5-1", "uniprot_id": "I3L7E5_PIG", "mass": 90970.0, "length": 808, "protein_name": "DNA replication licensing factor MCM3", "gene_name": "MCM3", "organism": "Pig", "refseq_name": "DNA replication licensing factor MCM3", "refseq_ac": "XP_001924848", "gene_names_uniprotkb": "MCM3", "gene_names_refseq": "MCM3", "protein_names_uniprotkb": "DNA replication licensing factor MCM3; 3.6.4.12", "protein_names_refseq": "DNA replication licensing factor MCM3", "tax_id": 9823, "disease": "", "pathway": " (ssc:100154824); (R-SSC-176187); (R-SSC-68867); (R-SSC-68949); (R-SSC-68962); (R-SSC-69052)", "pathway_count": 6, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Acts as a component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. Core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for the entry in S phase and for cell division., [UniProtKB, UniProtKB]; Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0003697 single-stranded DNA binding;GO:0003678 DNA helicase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0048471 perinuclear region of cytoplasm;GO:0005694 chromosome;GO:0042555 MCM complex", "go_biological_process": "GO:0006271 DNA strand elongation involved in DNA replication;GO:1902975 mitotic DNA replication initiation;GO:0000727 double-strand break repair via break-induced replication", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "I3L7E5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "I3L7X1-1", "uniprot_id": "I3L7X1_PIG", "mass": 119098.0, "length": 1043, "protein_name": "V(D)J recombination-activating protein 1", "gene_name": "RAG1", "organism": "Pig", "refseq_name": "V(D)J recombination-activating protein 1 isoform X1", "refseq_ac": "XP_020937084", "gene_names_uniprotkb": "RAG1", "gene_names_refseq": "RAG-1; RAG1", "protein_names_uniprotkb": "V(D)J recombination-activating protein 1; 2.3.2.27; 3.1.-.-", "protein_names_refseq": "V(D)J recombination-activating protein 1 isoform X1", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T-lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break between the RSS and the adjacent coding segment. RAG2 is not a catalytic component but is required for all known catalytic activities. DNA cleavage occurs in 2 steps: a first nick is introduced in the top strand immediately upstream of the heptamer, generating a 3'-hydroxyl group that can attack the phosphodiester bond on the opposite strand in a direct transesterification reaction, thereby creating 4 DNA ends: 2 hairpin coding ends and 2 blunt, 5'-phosphorylated ends., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A5G2QEE1;A0A8D1QRJ9", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0016787 hydrolase activity;GO:0042803 protein homodimerization activity;GO:0061630 ubiquitin protein ligase activity;GO:0004519 endonuclease activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0097519 DNA recombinase complex;GO:1905347 endodeoxyribonuclease complex", "go_biological_process": "GO:0002250 adaptive immune response;GO:0006325 chromatin organization;GO:0051865 protein autoubiquitination;GO:0033077 T cell differentiation in thymus;GO:0002331 pre-B cell allelic exclusion", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "I3L7X1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "I3L807-1", "uniprot_id": "I3L807_PIG", "mass": 69507.0, "length": 653, "protein_name": "sphingosine kinase", "gene_name": "SPHK2", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "SPHK2", "gene_names_refseq": "", "protein_names_uniprotkb": "sphingosine kinase; 2.7.1.91", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-1660661)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0042393 histone binding;GO:0038036 sphingosine-1-phosphate receptor activity;GO:0008481 sphingosine kinase activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005743 mitochondrial inner membrane;GO:0005783 endoplasmic reticulum;GO:0005829 cytosol", "go_biological_process": "GO:0032736 positive regulation of interleukin-13 production;GO:0035556 intracellular signal transduction;GO:0043065 positive regulation of apoptotic process;GO:0032755 positive regulation of interleukin-6 production;GO:0043306 positive regulation of mast cell degranulation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "I3L807-1", "record_type": "protein" }, { "uniprot_canonical_ac": "I3L8X4-1", "uniprot_id": "I3L8X4_PIG", "mass": 34273.0, "length": 311, "protein_name": "Serine/threonine-protein kinase", "gene_name": "PIM2", "organism": "Pig", "refseq_name": "serine/threonine-protein kinase pim-2", "refseq_ac": "XP_003360359", "gene_names_uniprotkb": "PIM2", "gene_names_refseq": "PIM2", "protein_names_uniprotkb": "Serine/threonine-protein kinase; 2.7.11.1", "protein_names_refseq": "serine/threonine-protein kinase pim-2", "tax_id": 9823, "disease": "", "pathway": " (ssc:100621339)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0008285 negative regulation of cell population proliferation;GO:0043066 negative regulation of apoptotic process;GO:0006915 apoptotic process;GO:0007346 regulation of mitotic cell cycle;GO:0009615 response to virus", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "I3L8X4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "I3L9P4-1", "uniprot_id": "I3L9P4_PIG", "mass": 139242.0, "length": 1259, "protein_name": "Adenylate cyclase type 5", "gene_name": "ADCY5", "organism": "Pig", "refseq_name": "adenylate cyclase type 5 isoform X1", "refseq_ac": "XP_020925901", "gene_names_uniprotkb": "ADCY5", "gene_names_refseq": "ADCY5", "protein_names_uniprotkb": "Adenylate cyclase type 5; 4.6.1.1", "protein_names_refseq": "adenylate cyclase type 5 isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100155970); (R-SSC-163615); (R-SSC-170660); (R-SSC-170670); (R-SSC-418597); (R-SSC-5610787)", "pathway_count": 6, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. Mediates signaling downstream of ADRB1. Regulates the increase of free cytosolic Ca(2+) in response to increased blood glucose levels and contributes to the regulation of Ca(2+)-dependent insulin secretion., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004016 adenylate cyclase activity;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0008179 adenylate cyclase binding;GO:0097110 scaffold protein binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005929 cilium", "go_biological_process": "GO:0006171 cAMP biosynthetic process;GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007204 positive regulation of cytosolic calcium ion concentration;GO:0035556 intracellular signal transduction;GO:1904322 cellular response to forskolin", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "I3L9P4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "I3LCR6-1", "uniprot_id": "I3LCR6_PIG", "mass": 90635.0, "length": 826, "protein_name": "Cadherin 3", "gene_name": "CDH3", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "CDH3", "gene_names_refseq": "", "protein_names_uniprotkb": "Cadherin 3", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-418990)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Cadherins are calcium-dependent cell adhesion proteins., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005509 calcium ion binding;GO:0045296 cadherin binding;GO:0008013 beta-catenin binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005912 adherens junction;GO:0016342 catenin complex;GO:0030057 desmosome", "go_biological_process": "GO:0048820 hair follicle maturation;GO:0016477 cell migration;GO:0031424 keratinization;GO:0000902 cell morphogenesis;GO:0001895 retina homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "I3LCR6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "I3LDM2-1", "uniprot_id": "I3LDM2_PIG", "mass": 55592.0, "length": 503, "protein_name": "Cytochrome P450 family 27 subfamily B member 1", "gene_name": "CYP27B1; METTL1", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "CYP27B1; METTL1; CYP27B1", "gene_names_refseq": "", "protein_names_uniprotkb": "Cytochrome P450 family 27 subfamily B member 1", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-196791); (R-SSC-211916)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0004498 calcidiol 1-monooxygenase activity;GO:0062185 secalciferol 1-monooxygenase activity;GO:0004497 monooxygenase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane", "go_biological_process": "GO:0042369 vitamin D catabolic process;GO:0008285 negative regulation of cell population proliferation;GO:0032496 response to lipopolysaccharide;GO:0030308 negative regulation of cell growth;GO:0043627 response to estrogen", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "I3LDM2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "I3LE15-1", "uniprot_id": "I3LE15_PIG", "mass": 21586.0, "length": 217, "protein_name": "Transcription initiation factor TFIID subunit 10", "gene_name": "TAF10", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "TAF10", "gene_names_refseq": "", "protein_names_uniprotkb": "Transcription initiation factor TFIID subunit 10", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-5689880); (R-SSC-674695); (R-SSC-6804756); (R-SSC-73776); (R-SSC-73779); (R-SSC-75953); (R-SSC-76042)", "pathway_count": 7, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "The TFIID basal transcription factor complex plays a major role in the initiation of RNA polymerase II (Pol II)-dependent transcription., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0042802 identical protein binding;GO:0030331 nuclear estrogen receptor binding;GO:0070063 RNA polymerase binding;GO:0004402 histone acetyltransferase activity", "go_cellular_component": "GO:0097550 transcription preinitiation complex;GO:0033276 transcription factor TFTC complex;GO:0048471 perinuclear region of cytoplasm;GO:0005669 transcription factor TFIID complex;GO:0000124 SAGA complex", "go_biological_process": "GO:0060261 positive regulation of transcription initiation by RNA polymerase II;GO:0001756 somitogenesis;GO:0006367 transcription initiation at RNA polymerase II promoter;GO:0060173 limb development;GO:0001892 embryonic placenta development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "I3LE15-1", "record_type": "protein" }, { "uniprot_canonical_ac": "I3LE69-1", "uniprot_id": "I3LE69_PIG", "mass": 110676.0, "length": 985, "protein_name": "Piwi-like protein 2", "gene_name": "PIWIL2", "organism": "Pig", "refseq_name": "piwi-like protein 2 isoform X1", "refseq_ac": "XP_005657266", "gene_names_uniprotkb": "PIWIL2", "gene_names_refseq": "PIWIL2", "protein_names_uniprotkb": "Piwi-like protein 2", "protein_names_refseq": "piwi-like protein 2 isoform X1", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003729 mRNA binding;GO:0016787 hydrolase activity;GO:0004521 RNA endonuclease activity;GO:0034584 piRNA binding", "go_cellular_component": "GO:0010370 perinucleolar chromocenter;GO:0005634 nucleus;GO:0097433 dense body;GO:1990923 PET complex;GO:0071546 pi-body", "go_biological_process": "GO:2000767 positive regulation of cytoplasmic translation;GO:0007283 spermatogenesis;GO:0031047 regulatory ncRNA-mediated gene silencing;GO:0048477 oogenesis;GO:0042754 negative regulation of circadian rhythm", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "I3LE69-1", "record_type": "protein" }, { "uniprot_canonical_ac": "I3LEI8-1", "uniprot_id": "I3LEI8_PIG", "mass": 21577.0, "length": 179, "protein_name": "Acireductone dioxygenase", "gene_name": "ADI1", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "ADI1; MTCBP1", "gene_names_refseq": "", "protein_names_uniprotkb": "Acireductone dioxygenase; 1.13.11.53; 1.13.11.54; ARD'; ARD; Acireductone dioxygenase (Fe(2+)-requiring); Acireductone dioxygenase (Ni(2+)-requiring); Fe-ARD; MTCBP-1; Membrane-type 1 matrix metalloproteinase cytoplasmic tail-binding protein 1; Ni-ARD", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-1237112)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway. Also down-regulates cell migration mediated by MMP14., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005506 iron ion binding;GO:0016151 nickel cation binding;GO:0010309 acireductone dioxygenase [iron(II)-requiring] activity;GO:0010308 acireductone dioxygenase (Ni2+-requiring) activity", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005886 plasma membrane", "go_biological_process": "GO:0019509 L-methionine salvage from methylthioadenosine;GO:0006555 methionine metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "I3LEI8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "I3LEN5-1", "uniprot_id": "I3LEN5_PIG", "mass": 36466.0, "length": 326, "protein_name": "Adenosine receptor A1", "gene_name": "ADORA1", "organism": "Pig", "refseq_name": "adenosine receptor A1 isoform X2", "refseq_ac": "XP_005653779", "gene_names_uniprotkb": "ADORA1", "gene_names_refseq": "ADORA1", "protein_names_uniprotkb": "Adenosine receptor A1", "protein_names_refseq": "adenosine receptor A1 isoform X2", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-417973); (R-SSC-418594)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A4X1UNZ2", "ec_number_list": "", "go_molecular_function": "GO:0001609 G protein-coupled adenosine receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0030425 dendrite;GO:0043197 dendritic spine;GO:0045202 synapse", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway;GO:0014074 response to purine-containing compound;GO:0051930 regulation of sensory perception of pain;GO:0042310 vasoconstriction", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "I3LEN5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "I3LUA0-1", "uniprot_id": "I3LUA0_PIG", "mass": 56699.0, "length": 501, "protein_name": "Endothelial lipase", "gene_name": "LIPG", "organism": "Pig", "refseq_name": "endothelial lipase precursor", "refseq_ac": "NP_001229958", "gene_names_uniprotkb": "LIPG", "gene_names_refseq": "EL; LIPG", "protein_names_uniprotkb": "Endothelial lipase; 3.1.1.32; 3.1.1.3; Phospholipase A1", "protein_names_refseq": "endothelial lipase precursor; lipase, endothelial", "tax_id": 9823, "disease": "", "pathway": " (ssc:100155736); (R-SSC-8964058)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "15953354;32543654", "class_list": "", "function": "Brain capillary endothelial cells synthesize and secrete endothelial lipase (EL); EL can generate fatty acids at blood-brain barrier for transport to deeper regions of the brain as building blocks for membrane phospholipids., [RefSeq, PubMed]; Exerts both phospholipase and triglyceride lipase activities. More active as a phospholipase than a triglyceride lipase. Hydrolyzes triglycerides, both with short-chain fatty acyl groups (tributyrin) and long-chain fatty acyl groups (triolein) with similar levels of activity toward both types of substrates. Hydrolyzes high density lipoproteins (HDL) more efficiently than other lipoproteins., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008201 heparin binding;GO:0004465 lipoprotein lipase activity;GO:0046872 metal ion binding;GO:0008970 phospholipase A1 activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0005615 extracellular space;GO:0005769 early endosome;GO:0005794 Golgi apparatus;GO:0009986 cell surface", "go_biological_process": "GO:0016042 lipid catabolic process;GO:0006633 fatty acid biosynthetic process;GO:0034375 high-density lipoprotein particle remodeling;GO:0042632 cholesterol homeostasis;GO:0043691 reverse cholesterol transport", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "I3LUA0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "I3LF82-1", "uniprot_id": "I3LF82_PIG", "mass": 95679.0, "length": 849, "protein_name": "Aryl hydrocarbon receptor", "gene_name": "AHR", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "AHR", "gene_names_refseq": "", "protein_names_uniprotkb": "Aryl hydrocarbon receptor", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-211945); (R-SSC-211976); (R-SSC-211981); (R-SSC-8937144)", "pathway_count": 4, "publication_count": 2, "publication_id_list": "32543654;39900897", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0046982 protein heterodimerization activity;GO:0000976 transcription cis-regulatory region binding;GO:0000987 cis-regulatory region sequence-specific DNA binding;GO:0004879 nuclear receptor activity;GO:0001094 TFIID-class transcription factor complex binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005829 cytosol;GO:0034751 aryl hydrocarbon receptor complex;GO:0034753 nuclear aryl hydrocarbon receptor complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0071320 cellular response to cAMP;GO:0050728 negative regulation of inflammatory response", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "I3LF82-1", "record_type": "protein" }, { "uniprot_canonical_ac": "I3LG23-1", "uniprot_id": "I3LG23_PIG", "mass": 139873.0, "length": 1290, "protein_name": "Macrophage-stimulating protein receptor", "gene_name": "MST1R", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "MST1R", "gene_names_refseq": "", "protein_names_uniprotkb": "Macrophage-stimulating protein receptor; 2.7.10.1; p185-Ron", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-8852405)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0019899 enzyme binding;GO:0004714 transmembrane receptor protein tyrosine kinase activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0043235 receptor complex;GO:0001725 stress fiber;GO:0005773 vacuole", "go_biological_process": "GO:0007169 cell surface receptor protein tyrosine kinase signaling pathway;GO:0007399 nervous system development;GO:0016477 cell migration;GO:0045087 innate immune response;GO:0051897 positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "I3LG23-1", "record_type": "protein" }, { "uniprot_canonical_ac": "I3LH37-1", "uniprot_id": "I3LH37_PIG", "mass": 67889.0, "length": 599, "protein_name": "Baculoviral IAP repeat containing 2", "gene_name": "BIRC2", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "BIRC2", "gene_names_refseq": "", "protein_names_uniprotkb": "Baculoviral IAP repeat containing 2", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-111465); (R-SSC-5357786); (R-SSC-5357905); (R-SSC-5357956); (R-SSC-5668541); (R-SSC-5675482); (R-SSC-5676594); (R-SSC-5689880); (R-SSC-937041); (R-SSC-9958825)", "pathway_count": 10, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003713 transcription coactivator activity;GO:0008270 zinc ion binding;GO:0042802 identical protein binding;GO:0051087 protein-folding chaperone binding;GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0009898 cytoplasmic side of plasma membrane", "go_biological_process": "GO:0043066 negative regulation of apoptotic process;GO:0006915 apoptotic process;GO:0043123 positive regulation of canonical NF-kappaB signal transduction;GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0031398 positive regulation of protein ubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "I3LH37-1", "record_type": "protein" }, { "uniprot_canonical_ac": "I3LH92-1", "uniprot_id": "I3LH92_PIG", "mass": 28959.0, "length": 271, "protein_name": "Aquaporin-2", "gene_name": "AQP2", "organism": "Pig", "refseq_name": "aquaporin-2", "refseq_ac": "NP_001121948", "gene_names_uniprotkb": "AQP2", "gene_names_refseq": "AQP2", "protein_names_uniprotkb": "Aquaporin-2; ADH water channel; Aquaporin-CD; Collecting duct water channel protein; WCH-CD; Water channel protein for renal collecting duct", "protein_names_refseq": "aquaporin 2 (collecting duct); aquaporin-2", "tax_id": 9823, "disease": "", "pathway": " (ssc:100147810); (R-SSC-432040); (R-SSC-432047)", "pathway_count": 3, "publication_count": 4, "publication_id_list": "22403603;22859853;27089501;32543654", "class_list": "", "function": "AQP1, AQP2, and AQP3, and V2R expression increased with gestation age in the fetal kidney, suggesting that this induction might contribute to the maturation of urinary concentrating capacity, [RefSeq, PubMed]; Aquaporin 2 promotes cell migration and epithelial morphogenesis., [RefSeq, PubMed]; Data provide evidence supporting the role of S256 and S269 in the maintenance of AQP2 at the cell surface., [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "B2MW86", "ec_number_list": "", "go_molecular_function": "GO:0015168 glycerol transmembrane transporter activity;GO:0015250 water channel activity", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0005886 plasma membrane;GO:0016323 basolateral plasma membrane;GO:0048471 perinuclear region of cytoplasm;GO:0055037 recycling endosome", "go_biological_process": "GO:0003091 renal water homeostasis;GO:0007015 actin filament organization;GO:0051289 protein homotetramerization;GO:0006833 water transport;GO:0071280 cellular response to copper ion", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "I3LH92-1", "record_type": "protein" }, { "uniprot_canonical_ac": "I3LHS8-1", "uniprot_id": "DCP1A_PIG", "mass": 62945.0, "length": 580, "protein_name": "mRNA-decapping enzyme 1A", "gene_name": "DCP1A", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "DCP1A; SMIF", "gene_names_refseq": "", "protein_names_uniprotkb": "mRNA-decapping enzyme 1A; 3.6.1.62; Smad4-interacting transcriptional co-activator; Transcription factor SMIF", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "30158128", "class_list": "", "function": "Necessary for the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. Removes the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP. Contributes to the transactivation of target genes after stimulation by TGFB1 (By similarity). Essential for embryonic development (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 15, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003729 mRNA binding;GO:0008047 enzyme activator activity;GO:0140933 5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] hydrolase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0000932 P-body", "go_biological_process": "GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA;GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "I3LHS8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "I3LIS0-1", "uniprot_id": "I3LIS0_PIG", "mass": 42742.0, "length": 382, "protein_name": "Sphingosine 1-phosphate receptor 1", "gene_name": "S1PR1", "organism": "Pig", "refseq_name": "sphingosine 1-phosphate receptor 1", "refseq_ac": "XP_020945787", "gene_names_uniprotkb": "S1PR1", "gene_names_refseq": "S1PR1", "protein_names_uniprotkb": "Sphingosine 1-phosphate receptor 1; Sphingosine 1-phosphate receptor Edg-1", "protein_names_refseq": "sphingosine 1-phosphate receptor 1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100621202); (R-SSC-419408)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A4X1TRU9", "ec_number_list": "", "go_molecular_function": "GO:0001664 G protein-coupled receptor binding;GO:0038036 sphingosine-1-phosphate receptor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0009897 external side of plasma membrane;GO:0098793 presynapse", "go_biological_process": "GO:0045124 regulation of bone resorption;GO:0003376 sphingosine-1-phosphate receptor signaling pathway;GO:0001525 angiogenesis;GO:0006935 chemotaxis;GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "I3LIS0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "I3LJB7-1", "uniprot_id": "I3LJB7_PIG", "mass": 126520.0, "length": 1102, "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform", "gene_name": "PIK3CG", "organism": "Pig", "refseq_name": "phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform isoform X1", "refseq_ac": "XP_020957862", "gene_names_uniprotkb": "PIK3CG", "gene_names_refseq": "PIK3CG; p120-PI3K", "protein_names_uniprotkb": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform; 2.7.1.137; 2.7.1.153; 2.7.1.154; 2.7.11.1; Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit gamma; Phosphoinositide-3-kinase catalytic gamma polypeptide; Serine/threonine protein kinase PIK3CG; p120-PI3K", "protein_names_refseq": "phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform isoform X1", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-114604); (R-SSC-1257604); (R-SSC-1660499); (R-SSC-389357); (R-SSC-392451); (R-SSC-6811558); (R-SSC-9027276); (R-SSC-9927354)", "pathway_count": 8, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0042802 identical protein binding;GO:0046875 ephrin receptor binding;GO:0016303 1-phosphatidylinositol-3-kinase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0005944 phosphatidylinositol 3-kinase complex, class IB;GO:0005943 phosphatidylinositol 3-kinase complex, class IA", "go_biological_process": "GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process;GO:0003376 sphingosine-1-phosphate receptor signaling pathway;GO:0001525 angiogenesis;GO:0006897 endocytosis;GO:0006935 chemotaxis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "I3LJB7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "I3LJU2-1", "uniprot_id": "I3LJU2_PIG", "mass": 35916.0, "length": 347, "protein_name": "Transcription factor JunB", "gene_name": "JUNB", "organism": "Pig", "refseq_name": "transcription factor jun-B", "refseq_ac": "XP_005674540", "gene_names_uniprotkb": "JUNB", "gene_names_refseq": "JUNB", "protein_names_uniprotkb": "Transcription factor JunB; Transcription factor AP-1 subunit JunB", "protein_names_refseq": "transcription factor jun-B", "tax_id": 9823, "disease": "", "pathway": " (ssc:100523358)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005667 transcription regulator complex;GO:0035976 transcription factor AP-1 complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0042127 regulation of cell population proliferation;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0048545 response to steroid hormone;GO:0051726 regulation of cell cycle", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "I3LJU2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "I3LKM5-1", "uniprot_id": "I3LKM5_PIG", "mass": 21272.0, "length": 185, "protein_name": "Homeobox expressed in ES cells 1", "gene_name": "HESX1", "organism": "Pig", "refseq_name": "homeobox expressed in ES cells 1", "refseq_ac": "XP_020924663", "gene_names_uniprotkb": "HESX1", "gene_names_refseq": "HESX1", "protein_names_uniprotkb": "Homeobox expressed in ES cells 1", "protein_names_refseq": "homeobox expressed in ES cells 1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100623612)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003682 chromatin binding;GO:0042803 protein homodimerization activity;GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006357 regulation of transcription by RNA polymerase II;GO:0021983 pituitary gland development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "I3LKM5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "I3LLJ0-1", "uniprot_id": "I3LLJ0_PIG", "mass": 43475.0, "length": 389, "protein_name": "Nucleic acid dioxygenase ALKBH1", "gene_name": "ALKBH1", "organism": "Pig", "refseq_name": "nucleic acid dioxygenase ALKBH1", "refseq_ac": "XP_020955215", "gene_names_uniprotkb": "ALKBH1", "gene_names_refseq": "ALKBH1", "protein_names_uniprotkb": "Nucleic acid dioxygenase ALKBH1; 1.14.11.33; 1.14.11.51; 4.2.99.18; Alkylated DNA repair protein alkB homolog 1; Alpha-ketoglutarate-dependent dioxygenase ABH1; DNA 6mA demethylase; DNA N6-methyl adenine demethylase ALKBH1; DNA lyase ABH1; DNA oxidative demethylase ALKBH1; mRNA N(3)-methylcytidine demethylase", "protein_names_refseq": "nucleic acid dioxygenase ALKBH1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100623752)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0042056 chemoattractant activity;GO:0000049 tRNA binding;GO:0008198 ferrous iron binding;GO:0140078 class I DNA-(apurinic or apyrimidinic site) endonuclease activity;GO:1990984 tRNA demethylase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0000791 euchromatin", "go_biological_process": "GO:0006281 DNA repair;GO:0006351 DNA-templated transcription;GO:0002101 tRNA wobble cytosine modification;GO:0006448 regulation of translational elongation;GO:0042245 RNA repair", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "I3LLJ0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "I3LLK4-1", "uniprot_id": "I3LLK4_PIG", "mass": 53093.0, "length": 489, "protein_name": "Prostaglandin E2 receptor EP4 subtype", "gene_name": "PTGER4", "organism": "Pig", "refseq_name": "prostaglandin E receptor 4", "refseq_ac": "XP_020932314", "gene_names_uniprotkb": "PTGER4", "gene_names_refseq": "PTGER4", "protein_names_uniprotkb": "Prostaglandin E2 receptor EP4 subtype; Prostanoid EP4 receptor", "protein_names_refseq": "prostaglandin E receptor 4 subtype EP4; prostaglandin E receptor 4", "tax_id": 9823, "disease": "", "pathway": " (ssc:100625072); (R-SSC-391908)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. Has a relaxing effect on smooth muscle. May play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004957 prostaglandin E receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0033624 negative regulation of integrin activation;GO:0006954 inflammatory response;GO:0006955 immune response;GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0007193 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "I3LLK4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "I3LMT9-1", "uniprot_id": "I3LMT9_PIG", "mass": 43918.0, "length": 387, "protein_name": "B2 bradykinin receptor", "gene_name": "BDKRB2", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "BDKRB2", "gene_names_refseq": "", "protein_names_uniprotkb": "B2 bradykinin receptor", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (ssc:110255240)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Receptor for bradykinin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0002020 protease binding;GO:0016493 C-C chemokine receptor activity;GO:0019957 C-C chemokine binding;GO:0046982 protein heterodimerization activity;GO:0031702 type 1 angiotensin receptor binding", "go_cellular_component": "GO:0005768 endosome;GO:0009897 external side of plasma membrane", "go_biological_process": "GO:0006939 smooth muscle contraction;GO:0006955 immune response;GO:0007204 positive regulation of cytosolic calcium ion concentration;GO:0019722 calcium-mediated signaling;GO:0042311 vasodilation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "I3LMT9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "I3LQQ6-1", "uniprot_id": "I3LQQ6_PIG", "mass": 45375.0, "length": 401, "protein_name": "Plasminogen activator inhibitor 1", "gene_name": "SERPINE1", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "SERPINE1", "gene_names_refseq": "", "protein_names_uniprotkb": "Plasminogen activator inhibitor 1; Endothelial plasminogen activator inhibitor; Serpin E1", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-114608); (R-SSC-3000178); (R-SSC-75205); (R-SSC-9769739)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Serine protease inhibitor. Inhibits TMPRSS7. Is a primary inhibitor of tissue-type plasminogen activator (PLAT) and urokinase-type plasminogen activator (PLAU). As PLAT inhibitor, it is required for fibrinolysis down-regulation and is responsible for the controlled degradation of blood clots. As PLAU inhibitor, it is involved in the regulation of cell adhesion and spreading. Acts as a regulator of cell migration, independently of its role as protease inhibitor. It is required for stimulation of keratinocyte migration during cutaneous injury repair. It is involved in cellular and replicative senescence. Plays a role in alveolar type 2 cells senescence in the lung. Is involved in the regulation of cementogenic differentiation of periodontal ligament stem cells, and regulates odontoblast differentiation and dentin formation during odontogenesis., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0002020 protease binding;GO:0004867 serine-type endopeptidase inhibitor activity;GO:0005102 signaling receptor binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0031012 extracellular matrix;GO:0070062 extracellular exosome", "go_biological_process": "GO:0097187 dentinogenesis;GO:1901331 positive regulation of odontoblast differentiation;GO:0035491 positive regulation of leukotriene production involved in inflammatory response;GO:0061044 negative regulation of vascular wound healing;GO:0001525 angiogenesis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "I3LQQ6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "I3LRD8-1", "uniprot_id": "I3LRD8_PIG", "mass": 64933.0, "length": 591, "protein_name": "Frizzled class receptor 9", "gene_name": "FZD9", "organism": "Pig", "refseq_name": "frizzled-9", "refseq_ac": "XP_013850981", "gene_names_uniprotkb": "FZD9", "gene_names_refseq": "FZD9", "protein_names_uniprotkb": "Frizzled class receptor 9", "protein_names_refseq": "frizzled-9", "tax_id": 9823, "disease": "", "pathway": " (ssc:100625784)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0042803 protein homodimerization activity;GO:0046982 protein heterodimerization activity;GO:0017147 Wnt-protein binding;GO:0042813 Wnt receptor activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0009986 cell surface;GO:0048471 perinuclear region of cytoplasm;GO:0031527 filopodium membrane", "go_biological_process": "GO:0043524 negative regulation of neuron apoptotic process;GO:0030501 positive regulation of bone mineralization;GO:0060070 canonical Wnt signaling pathway;GO:0090263 positive regulation of canonical Wnt signaling pathway;GO:2000179 positive regulation of neural precursor cell proliferation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "I3LRD8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "I3LS43-1", "uniprot_id": "I3LS43_PIG", "mass": 69821.0, "length": 605, "protein_name": "Protein Spindly", "gene_name": "SPDL1", "organism": "Pig", "refseq_name": "protein Spindly isoform X2", "refseq_ac": "XP_003134111", "gene_names_uniprotkb": "SPDL1; CCDC99", "gene_names_refseq": "SPDL1", "protein_names_uniprotkb": "Protein Spindly; Coiled-coil domain-containing protein 99; Spindle apparatus coiled-coil domain-containing protein 1", "protein_names_refseq": "protein Spindly isoform X2", "tax_id": 9823, "disease": "", "pathway": " (ssc:100510938); (R-SSC-141430); (R-SSC-141444); (R-SSC-2467813); (R-SSC-2500257); (R-SSC-5663220); (R-SSC-68877); (R-SSC-9648025)", "pathway_count": 8, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Required for the localization of dynein and dynactin to the mitotic kinetochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex. Also required for correct spindle orientation. Does not appear to be required for the removal of spindle assembly checkpoint (SAC) proteins from the kinetochore upon bipolar spindle attachment. Acts as an adapter protein linking the dynein motor complex to various cargos and converts dynein from a non-processive to a highly processive motor in the presence of dynactin. Facilitates the interaction between dynein and dynactin and activates dynein processivity (the ability to move along a microtubule for a long distance without falling off the track). Plays a role in cell migration., [UniProtKB, UniProtKB]; Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex. Also required for correct spindle orientation. Does not appear to be required for the removal of spindle assembly checkpoint (SAC) proteins from the kinetochore upon bipolar spindle attachment., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A4X1U4Y5", "ec_number_list": "", "go_molecular_function": "GO:0019899 enzyme binding;GO:0043515 kinetochore binding", "go_cellular_component": "GO:0000922 spindle pole;GO:0005634 nucleus;GO:0005813 centrosome;GO:0000940 outer kinetochore", "go_biological_process": "GO:0016477 cell migration;GO:0051301 cell division;GO:0007094 mitotic spindle assembly checkpoint signaling;GO:0007080 mitotic metaphase chromosome alignment;GO:0000132 establishment of mitotic spindle orientation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "I3LS43-1", "record_type": "protein" }, { "uniprot_canonical_ac": "I3LT36-1", "uniprot_id": "I3LT36_PIG", "mass": 103194.0, "length": 951, "protein_name": "Mitogen-activated protein kinase kinase kinase", "gene_name": "MAP3K10", "organism": "Pig", "refseq_name": "mitogen-activated protein kinase kinase kinase 10", "refseq_ac": "XP_020950036", "gene_names_uniprotkb": "MAP3K10", "gene_names_refseq": "MAP3K10", "protein_names_uniprotkb": "Mitogen-activated protein kinase kinase kinase; 2.7.11.25", "protein_names_refseq": "mitogen-activated protein kinase kinase kinase 10", "tax_id": 9823, "disease": "", "pathway": " (ssc:100521453)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0043425 bHLH transcription factor binding;GO:0004706 JUN kinase kinase kinase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0007165 signal transduction;GO:0043065 positive regulation of apoptotic process;GO:0046330 positive regulation of JNK cascade;GO:0007224 smoothened signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "I3LT36-1", "record_type": "protein" }, { "uniprot_canonical_ac": "I3LT94-1", "uniprot_id": "I3LT94_PIG", "mass": 72969.0, "length": 672, "protein_name": "Leucine zipper putative tumor suppressor 2", "gene_name": "LZTS2", "organism": "Pig", "refseq_name": "leucine zipper putative tumor suppressor 2 isoform X1", "refseq_ac": "XP_020928330", "gene_names_uniprotkb": "LZTS2; LAPSER1", "gene_names_refseq": "LZTS2", "protein_names_uniprotkb": "Leucine zipper putative tumor suppressor 2; Protein LAPSER1", "protein_names_refseq": "leucine zipper putative tumor suppressor 2 isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100625806)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. May negatively regulate axonal outgrowth by preventing the formation of microtubule bundles that are necessary for transport within the elongating axon. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta-catenin., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005813 centrosome;GO:0005829 cytosol;GO:0005874 microtubule;GO:0031982 vesicle;GO:0030496 midbody", "go_biological_process": "GO:0051013 microtubule severing;GO:0090090 negative regulation of canonical Wnt signaling pathway;GO:0016055 Wnt signaling pathway;GO:0000281 mitotic cytokinesis;GO:0051168 nuclear export", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "I3LT94-1", "record_type": "protein" }, { "uniprot_canonical_ac": "I3LUE7-1", "uniprot_id": "I3LUE7_PIG", "mass": 39188.0, "length": 351, "protein_name": "C5a anaphylatoxin chemotactic receptor 1", "gene_name": "C5AR1", "organism": "Pig", "refseq_name": "C5a anaphylatoxin chemotactic receptor 1", "refseq_ac": "NP_001231144", "gene_names_uniprotkb": "C5AR1", "gene_names_refseq": "C5AR1; C5R1", "protein_names_uniprotkb": "C5a anaphylatoxin chemotactic receptor 1; C5a anaphylatoxin chemotactic receptor; Chemerin-like receptor 1; Chemokine-like receptor 1", "protein_names_refseq": "C5a anaphylatoxin chemotactic receptor 1; C5a anaphylatoxin receptor; complement component 5a receptor 1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100048955); (R-SSC-375276); (R-SSC-418594); (R-SSC-6798695); (R-SSC-977606)", "pathway_count": 5, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Receptor for the chemoattractant adipokine chemerin/RARRES2 and for the omega-3 fatty acid derived molecule resolvin E1. Interaction with RARRES2 initiates activation of G proteins G(i)/G(o) and beta-arrestin pathways inducing cellular responses via second messenger pathways such as intracellular calcium mobilization, phosphorylation of MAP kinases MAPK1/MAPK3 (ERK1/2), TYRO3, MAPK14/P38MAPK and PI3K leading to multifunctional effects, like, reduction of immune responses, enhancing of adipogenesis and angionesis. Resolvin E1 down-regulates cytokine production in macrophages by reducing the activation of MAPK1/3 (ERK1/2) and NF-kappa-B. Positively regulates adipogenesis and adipocyte metabolism., [UniProtKB, UniProtKB]; Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a, stimulating chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors, such as adenylate cyclase. C5AR1 is coupled to G(i)/G(o) (GNAI1 or GNAO1) G alpha proteins and mediates inhibition of adenylate cyclase. The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0004878 complement component C5a receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016323 basolateral plasma membrane;GO:0045177 apical part of cell;GO:0031410 cytoplasmic vesicle", "go_biological_process": "GO:0002430 complement receptor mediated signaling pathway;GO:0001774 microglial cell activation;GO:0006935 chemotaxis;GO:0006954 inflammatory response;GO:0007193 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "I3LUE7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "I3LUN9-1", "uniprot_id": "I3LUN9_PIG", "mass": 215557.0, "length": 1956, "protein_name": "Plexin-A3", "gene_name": "PLXNA3", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "PLXNA3", "gene_names_refseq": "", "protein_names_uniprotkb": "Plexin-A3", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-399954); (R-SSC-399955); (R-SSC-399956)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Coreceptor for SEMA3A and SEMA3F. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance in the developing nervous system. Regulates the migration of sympathetic neurons, but not of neural crest precursors. Required for normal dendrite spine morphology in pyramidal neurons. May play a role in regulating semaphorin-mediated programmed cell death in the developing nervous system. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0017154 semaphorin receptor activity", "go_cellular_component": "GO:0002116 semaphorin receptor complex;GO:0005886 plasma membrane", "go_biological_process": "GO:0050770 regulation of axonogenesis;GO:0051495 positive regulation of cytoskeleton organization;GO:0071526 semaphorin-plexin signaling pathway;GO:0007416 synapse assembly;GO:0030334 regulation of cell migration", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "I3LUN9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "I3LVN3-1", "uniprot_id": "I3LVN3_PIG", "mass": 32836.0, "length": 280, "protein_name": "Inhibitor of growth protein", "gene_name": "ING2", "organism": "Pig", "refseq_name": "inhibitor of growth protein 2", "refseq_ac": "XP_003133390", "gene_names_uniprotkb": "ING2", "gene_names_refseq": "ING2", "protein_names_uniprotkb": "Inhibitor of growth protein", "protein_names_refseq": "inhibitor of growth protein 2", "tax_id": 9823, "disease": "", "pathway": " (ssc:100516113); (R-SSC-3899300); (R-SSC-6811555)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Component of an histone acetyltransferase complex., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0044877 protein-containing complex binding;GO:0035091 phosphatidylinositol binding;GO:0140002 histone H3K4me3 reader activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005886 plasma membrane;GO:0070822 Sin3-type complex;GO:0016602 CCAAT-binding factor complex", "go_biological_process": "GO:0048133 male germ-line stem cell asymmetric division;GO:0030317 flagellated sperm motility;GO:0007286 spermatid development;GO:0045893 positive regulation of DNA-templated transcription;GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "I3LVN3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "K7GKN4-1", "uniprot_id": "K7GKN4_PIG", "mass": 58515.0, "length": 513, "protein_name": "Zinc finger protein RFP", "gene_name": "TRIM27", "organism": "Pig", "refseq_name": "zinc finger protein RFP", "refseq_ac": "XP_003128283", "gene_names_uniprotkb": "TRIM27", "gene_names_refseq": "TRIM27", "protein_names_uniprotkb": "Zinc finger protein RFP; 2.3.2.27; Ret finger protein; Tripartite motif-containing protein 27", "protein_names_refseq": "zinc finger protein RFP", "tax_id": 9823, "disease": "", "pathway": " (ssc:100523617); (R-SSC-3232142); (R-SSC-8948751)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0003713 transcription coactivator activity;GO:0008270 zinc ion binding;GO:0042802 identical protein binding;GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005769 early endosome;GO:0005829 cytosol;GO:0031965 nuclear membrane", "go_biological_process": "GO:0032897 negative regulation of viral transcription;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0006351 DNA-templated transcription;GO:0045087 innate immune response;GO:0010507 negative regulation of autophagy", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "K7GKN4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "K7GLC7-1", "uniprot_id": "K7GLC7_PIG", "mass": 56354.0, "length": 487, "protein_name": "RING-type E3 ubiquitin transferase", "gene_name": "TRIM6", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "TRIM6", "gene_names_refseq": "", "protein_names_uniprotkb": "RING-type E3 ubiquitin transferase; 2.3.2.27", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0019901 protein kinase binding;GO:0030674 protein-macromolecule adaptor activity;GO:0042802 identical protein binding;GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0010629 negative regulation of gene expression;GO:0032496 response to lipopolysaccharide;GO:0045087 innate immune response;GO:0045071 negative regulation of viral genome replication;GO:0045892 negative regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "K7GLC7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "K7GN38-1", "uniprot_id": "K7GN38_PIG", "mass": 64340.0, "length": 558, "protein_name": "TNF receptor-associated factor", "gene_name": "TRAF5", "organism": "Pig", "refseq_name": "TNF receptor-associated factor 5 isoform X3", "refseq_ac": "XP_020919526", "gene_names_uniprotkb": "TRAF5", "gene_names_refseq": "TRAF5", "protein_names_uniprotkb": "TNF receptor-associated factor; 2.3.2.27", "protein_names_refseq": "TNF receptor-associated factor 5 isoform X3", "tax_id": 9823, "disease": "", "pathway": " (ssc:396616)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Adapter protein and signal transducer that links members of the tumor necrosis factor receptor family to different signaling pathways by association with the receptor cytoplasmic domain and kinases. Mediates activation of NF-kappa-B and probably JNK. Seems to be involved in apoptosis. Plays a role in mediating activation of NF-kappa-B by EIF2AK2/PKR., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0042802 identical protein binding;GO:0031625 ubiquitin protein ligase binding;GO:0031996 thioesterase binding;GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005813 centrosome;GO:0005829 cytosol;GO:0009898 cytoplasmic side of plasma membrane;GO:0035631 CD40 receptor complex", "go_biological_process": "GO:0023035 CD40 signaling pathway;GO:0007166 cell surface receptor signaling pathway;GO:0048255 mRNA stabilization;GO:0006915 apoptotic process;GO:0043123 positive regulation of canonical NF-kappaB signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "K7GN38-1", "record_type": "protein" }, { "uniprot_canonical_ac": "K7GNL1-1", "uniprot_id": "K7GNL1_PIG", "mass": 57437.0, "length": 515, "protein_name": "DNA-(apurinic or apyrimidinic site) endonuclease", "gene_name": "APEX2", "organism": "Pig", "refseq_name": "DNA-(apurinic or apyrimidinic site) lyase 2", "refseq_ac": "XP_003135157", "gene_names_uniprotkb": "APEX2", "gene_names_refseq": "APEX2", "protein_names_uniprotkb": "DNA-(apurinic or apyrimidinic site) endonuclease; 3.1.-.-", "protein_names_refseq": "DNA-(apurinic or apyrimidinic site) lyase 2", "tax_id": 9823, "disease": "", "pathway": " (ssc:100519003)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity;GO:0008081 phosphoric diester hydrolase activity;GO:0008311 double-stranded DNA 3'-5' DNA exonuclease activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005739 mitochondrion;GO:0001650 fibrillar center", "go_biological_process": "GO:0006310 DNA recombination;GO:0006284 base-excision repair", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "K7GNL1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "K7GPY3-1", "uniprot_id": "K7GPY3_PIG", "mass": 41367.0, "length": 389, "protein_name": "Ectodysplasin-A", "gene_name": "EDA", "organism": "Pig", "refseq_name": "ectodysplasin-A isoform X2", "refseq_ac": "XP_005657873", "gene_names_uniprotkb": "EDA", "gene_names_refseq": "EDA", "protein_names_uniprotkb": "Ectodysplasin-A", "protein_names_refseq": "ectodysplasin-A isoform X2", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-5669034)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005125 cytokine activity;GO:0005164 tumor necrosis factor receptor binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005886 plasma membrane;GO:0045177 apical part of cell;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006955 immune response;GO:0030154 cell differentiation;GO:0043123 positive regulation of canonical NF-kappaB signal transduction;GO:0042475 odontogenesis of dentin-containing tooth;GO:0042476 odontogenesis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "K7GPY3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "K7GR72-1", "uniprot_id": "K7GR72_PIG", "mass": 103868.0, "length": 924, "protein_name": "Anion exchange protein", "gene_name": "SLC4A1", "organism": "Pig", "refseq_name": "band 3 anion transport protein isoform X1", "refseq_ac": "XP_005668813", "gene_names_uniprotkb": "SLC4A1", "gene_names_refseq": "SLC4A1", "protein_names_uniprotkb": "Anion exchange protein", "protein_names_refseq": "band 3 anion transport protein isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100514249); (R-SSC-1237044); (R-SSC-1247673); (R-SSC-425381)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Functions both as a transporter that mediates electroneutral anion exchange across the cell membrane and as a structural protein. Component of the ankyrin-1 complex of the erythrocyte membrane; required for normal flexibility and stability of the erythrocyte membrane and for normal erythrocyte shape via the interactions of its cytoplasmic domain with cytoskeletal proteins, glycolytic enzymes, and hemoglobin. Functions as a transporter that mediates the 1:1 exchange of inorganic anions across the erythrocyte membrane. Mediates chloride-bicarbonate exchange in the kidney, and is required for normal acidification of the urine., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0042803 protein homodimerization activity;GO:0015293 symporter activity;GO:0030492 hemoglobin binding;GO:0015106 bicarbonate transmembrane transporter activity;GO:0030506 ankyrin binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016323 basolateral plasma membrane;GO:0009898 cytoplasmic side of plasma membrane;GO:0030863 cortical cytoskeleton;GO:0170014 ankyrin-1 complex", "go_biological_process": "GO:0055085 transmembrane transport;GO:0015701 bicarbonate transport;GO:0051453 regulation of intracellular pH", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "K7GR72-1", "record_type": "protein" }, { "uniprot_canonical_ac": "K7GSE8-1", "uniprot_id": "K7GSE8_PIG", "mass": 122596.0, "length": 1103, "protein_name": "Tyrosine-protein kinase", "gene_name": "JAK3", "organism": "Pig", "refseq_name": "tyrosine-protein kinase JAK3 isoform X1", "refseq_ac": "XP_003123548", "gene_names_uniprotkb": "JAK3", "gene_names_refseq": "JAK3", "protein_names_uniprotkb": "Tyrosine-protein kinase; 2.7.10.2", "protein_names_refseq": "tyrosine-protein kinase JAK3 isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100518649); (R-SSC-1266695); (R-SSC-201556); (R-SSC-5673001); (R-SSC-6785807); (R-SSC-8854691); (R-SSC-8983432); (R-SSC-8985947); (R-SSC-9020558); (R-SSC-9020958); (R-SSC-912526)", "pathway_count": 11, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004715 non-membrane spanning protein tyrosine kinase activity;GO:0005524 ATP binding;GO:0019903 protein phosphatase binding;GO:0005131 growth hormone receptor binding", "go_cellular_component": "GO:0005829 cytosol;GO:0005856 cytoskeleton;GO:0031234 extrinsic component of cytoplasmic side of plasma membrane;GO:0012505 endomembrane system", "go_biological_process": "GO:0035771 interleukin-4-mediated signaling pathway;GO:0038110 interleukin-2-mediated signaling pathway;GO:0030154 cell differentiation;GO:0035556 intracellular signal transduction;GO:0045087 innate immune response", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "K7GSE8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "K7GT60-1", "uniprot_id": "K7GT60_PIG", "mass": 36976.0, "length": 326, "protein_name": "Cyclin-dependent kinase 4", "gene_name": "CDK6", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "CDK6", "gene_names_refseq": "", "protein_names_uniprotkb": "Cyclin-dependent kinase 4; 2.7.11.22; Cell division protein kinase 4", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-2559580); (R-SSC-2559582); (R-SSC-2559585); (R-SSC-69231); (R-SSC-8934593); (R-SSC-9754119)", "pathway_count": 6, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A4X1U5M8;K7GRU6", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0098770 FBXO family protein binding;GO:0004693 cyclin-dependent protein serine/threonine kinase activity;GO:0030332 cyclin binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005813 centrosome;GO:0005829 cytosol", "go_biological_process": "GO:0007165 signal transduction;GO:0051301 cell division;GO:0000086 G2/M transition of mitotic cell cycle;GO:0050680 negative regulation of epithelial cell proliferation;GO:0009615 response to virus", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "K7GT60-1", "record_type": "protein" }, { "uniprot_canonical_ac": "O02670-1", "uniprot_id": "KCNJ5_PIG", "mass": 47778.0, "length": 419, "protein_name": "G protein-activated inward rectifier potassium channel 4", "gene_name": "KCNJ5", "organism": "Pig", "refseq_name": "G protein-activated inward rectifier potassium channel 4", "refseq_ac": "NP_999390", "gene_names_uniprotkb": "KCNJ5", "gene_names_refseq": "KCNJ5", "protein_names_uniprotkb": "G protein-activated inward rectifier potassium channel 4; CIR; Cardiac inward rectifier; GIRK-4; Heart KATP channel; Inward rectifier K(+) channel Kir3.4; KATP-1; Potassium channel, inwardly rectifying subfamily J member 5", "protein_names_refseq": "CIR; G protein-activated inward rectifier potassium channel 4; GIRK-4; KATP-1; cardiac inward rectifier; heart KATP channel; inward rectifier K(+) channel Kir3.4; inward rectifying K channel; potassium channel, inwardly rectifying subfamily J member 5; potassium voltage-gated channel subfamily J member 5", "tax_id": 9823, "disease": "", "pathway": " (ssc:397448); (R-SSC-1296041); (R-SSC-997272)", "pathway_count": 3, "publication_count": 2, "publication_id_list": "20118408;8834003", "class_list": "", "function": "Blockade of K(ATP) channels further diminished (approximately 45%) the repayment of flow debt in lean but not metabolic syndrome swine., [RefSeq, PubMed]; Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by external barium. This potassium channel is controlled by G proteins., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization;GO:0015467 G-protein activated inward rectifier potassium channel activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:1990566 I(KACh) inward rectifier potassium channel complex", "go_biological_process": "GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential;GO:0086091 regulation of heart rate by cardiac conduction;GO:1990573 potassium ion import across plasma membrane", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "O02670-1", "record_type": "protein" }, { "uniprot_canonical_ac": "O02799-1", "uniprot_id": "STAT2_PIG", "mass": 99061.0, "length": 864, "protein_name": "Signal transducer and activator of transcription 2", "gene_name": "STAT2", "organism": "Pig", "refseq_name": "signal transducer and activator of transcription 2", "refseq_ac": "NP_999054", "gene_names_uniprotkb": "STAT2", "gene_names_refseq": "STAT2", "protein_names_uniprotkb": "Signal transducer and activator of transcription 2", "protein_names_refseq": "signal transducer and activator of transcription 2", "tax_id": 9823, "disease": "", "pathway": " (ssc:396923); (R-SSC-8854691); (R-SSC-909733); (R-SSC-912694)", "pathway_count": 4, "publication_count": 4, "publication_id_list": "20739522;23449802;24554650;26546155", "class_list": "", "function": "Nsp1beta inhibits interferon-activated STAT1/STAT2 signal transduction by inducing karyopherin-alpha1 degradation., [RefSeq, PubMed]; Signal transducer and activator of transcription that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with IRF9/ISGF3G to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state. Acts as a regulator of mitochondrial fission by modulating the phosphorylation of DNM1L at 'Ser-616' and 'Ser-637' which activate and inactivate the GTPase activity of DNM1L respectively., [UniProtKB, UniProtKB]; Taken together, results of these experiments describe for the first time a novel mechanism by which foot-and-mouth disease virus evolves to inhibit IFN signaling via blocking STAT1/STAT2 nuclear translocation., [RefSeq, PubMed]; The majority of the STAT1/STAT2/IRF9 (IFN regulatory factor 9) heterotrimers remained in the cytoplasm of PRRSV-infected cells, which indicates that the nuclear translocation of the heterotrimers was blocked Erratum:[J Virol. 2011 Jun;85(11):5705], [RefSeq, PubMed]; While La Piedad Michoacan Mexico Virus V protein does not affect the protein levels of STAT1 or STAT2, it does prevent the interferon-induced phosphorylation and nuclear translocation of STAT1 and STAT2 thereby inhibiting cellular responses to interferon alpha/beta., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0042802 identical protein binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0044389 ubiquitin-like protein ligase binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0070721 ISGF3 complex", "go_biological_process": "GO:0090140 regulation of mitochondrial fission;GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0006952 defense response;GO:0042127 regulation of cell population proliferation", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "O02799-1", "record_type": "protein" }, { "uniprot_canonical_ac": "O02826-1", "uniprot_id": "MSMB_PIG", "mass": 12246.0, "length": 111, "protein_name": "Beta-microseminoprotein", "gene_name": "MSMB", "organism": "Pig", "refseq_name": "beta-microseminoprotein precursor", "refseq_ac": "NP_999017", "gene_names_uniprotkb": "MSMB; PSP94", "gene_names_refseq": "MSMB; PSP-94; PSP94; TS507", "protein_names_uniprotkb": "Beta-microseminoprotein; PSP-94; PSP94; Prostate secreted seminal plasma protein; Prostate secretory protein of 94 amino acids; TS507", "protein_names_refseq": "PSP94-like protein; beta-microseminoprotein precursor; beta-microseminoprotein; prostate secreted seminal plasma protein; prostate secretory protein of 94 amino acids", "tax_id": 9823, "disease": "", "pathway": " (ssc:396852)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "15701518;16930619;32532042;8117114;8562060", "class_list": "", "function": "NMR solution structure, [RefSeq, PubMed]; NMR structure of beta-microseminoprotein, [RefSeq, PubMed]; The Ubiquitin-Proteasome System Does Not Regulate the Degradation of Porcine beta-Microseminoprotein during Sperm Capacitation. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "O02826-1", "record_type": "protein" }, { "uniprot_canonical_ac": "O18994-1", "uniprot_id": "GPX5_PIG", "mass": 24936.0, "length": 219, "protein_name": "Epididymal secretory glutathione peroxidase", "gene_name": "GPX5", "organism": "Pig", "refseq_name": "epididymal secretory glutathione peroxidase precursor", "refseq_ac": "NP_999051", "gene_names_uniprotkb": "GPX5", "gene_names_refseq": "GPX5", "protein_names_uniprotkb": "Epididymal secretory glutathione peroxidase; 1.11.1.9; EGLP; Epididymis-specific glutathione peroxidase-like protein; GPx-5; GSHPx-5; Glutathione peroxidase 5", "protein_names_refseq": "EGLP; GPx-5; GSHPx-5; epididymal secretory glutathione peroxidase precursor; epididymal secretory glutathione peroxidase; epididymis-specific glutathione peroxidase 23kDa subunit; epididymis-specific glutathione peroxidase-like protein; glutathione peroxidase 5 (epididymal androgen-related protein)", "tax_id": 9823, "disease": "", "pathway": " (ssc:396920); (R-SSC-3299685)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "26711247;9271255", "class_list": "", "function": "May constitute a glutathione peroxidase-like protective system against peroxide damage in sperm membrane lipids. Since the purified porcine enzyme has very little activity towards hydrogen peroxide or organic hydroperoxides the protective effect is not likely to be exerted by its enzymatic activity. Instead, may protect sperm from premature acrosome reaction in the epididymis by binding to lipid peroxides, which might otherwise interact with phospholipase A2 and induce the acrosome reaction., [UniProtKB, PubMed]; Sperm TPI content and amounts of GPX5 in seminal plasma may be used as quality markers of boar sperm., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004602 glutathione peroxidase activity", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "GO:0034599 cellular response to oxidative stress", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "O18994-1", "record_type": "protein" }, { "uniprot_canonical_ac": "O19063-1", "uniprot_id": "SAMP_PIG", "mass": 25641.0, "length": 224, "protein_name": "Serum amyloid P-component", "gene_name": "APCS", "organism": "Pig", "refseq_name": "serum amyloid P-component precursor", "refseq_ac": "NP_999052", "gene_names_uniprotkb": "APCS", "gene_names_refseq": "APCS; SAP", "protein_names_uniprotkb": "Serum amyloid P-component; SAP", "protein_names_refseq": "serum amyloid P-component precursor; serum amyloid P-component", "tax_id": 9823, "disease": "", "pathway": " (ssc:396921)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0042802 identical protein binding;GO:0005509 calcium ion binding;GO:0030246 carbohydrate binding;GO:0001849 complement component C1q complex binding;GO:0046790 virion binding", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0045087 innate immune response;GO:0006953 acute-phase response;GO:0045656 negative regulation of monocyte differentiation;GO:0044871 negative regulation by host of viral glycoprotein metabolic process;GO:0046597 host-mediated suppression of symbiont invasion", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "O19063-1", "record_type": "protein" }, { "uniprot_canonical_ac": "O19071-1", "uniprot_id": "MGAT2_PIG", "mass": 51527.0, "length": 446, "protein_name": "Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase", "gene_name": "MGAT2", "organism": "Pig", "refseq_name": "alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase precursor", "refseq_ac": "NP_001121954", "gene_names_uniprotkb": "MGAT2; GNT2", "gene_names_refseq": "MGAT2", "protein_names_uniprotkb": "Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase; 2.4.1.143; Beta-1,2-N-acetylglucosaminyltransferase II; GNT-II; GlcNAc-T II; Mannoside acetylglucosaminyltransferase 2; N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase II", "protein_names_refseq": "GNT-II; N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase II; alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase precursor; beta-1,2-N-acetylglucosaminyltransferase II; glcNAc-T II; mannoside acetylglucosaminyltransferase 2; mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase", "tax_id": 9823, "disease": "", "pathway": " (ssc:100151745)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "9367162", "class_list": "", "function": "Plays an essential role in protein N-glycosylation. Catalyzes the transfer of N-acetylglucosamine (GlcNAc) onto the free terminal mannose moiety in the core structure of the nascent N-linked glycan chain, giving rise to the second branch in complex glycans., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008455 alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity;GO:0030145 manganese ion binding;GO:0042803 protein homodimerization activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005795 Golgi stack", "go_biological_process": "GO:0006487 protein N-linked glycosylation;GO:0009312 oligosaccharide biosynthetic process", "synthesized_glycan_count": 8635, "hit_score": 0.2, "record_id": "O19071-1", "record_type": "protein" }, { "uniprot_canonical_ac": "O19072-1", "uniprot_id": "OTC_PIG", "mass": 36738.0, "length": 328, "protein_name": "Ornithine transcarbamylase, mitochondrial", "gene_name": "OTC", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "OTC", "gene_names_refseq": "", "protein_names_uniprotkb": "Ornithine transcarbamylase, mitochondrial; 2.1.3.3; OTCase; Ornithine carbamoyltransferase, mitochondrial", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "9420013", "class_list": "", "function": "Catalyzes the second step of the urea cycle, the condensation of carbamoyl phosphate with L-ornithine to form L-citrulline. The urea cycle ensures the detoxification of ammonia by converting it to urea for excretion., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004585 ornithine carbamoyltransferase activity;GO:0016597 amino acid binding", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005743 mitochondrial inner membrane;GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0019240 citrulline biosynthetic process;GO:0000050 urea cycle;GO:0042450 L-arginine biosynthetic process via ornithine", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "O19072-1", "record_type": "protein" }, { "uniprot_canonical_ac": "O19073-1", "uniprot_id": "IL18_PIG", "mass": 22026.0, "length": 192, "protein_name": "Interleukin-18", "gene_name": "IL18", "organism": "Pig", "refseq_name": "interleukin-18", "refseq_ac": "NP_999162", "gene_names_uniprotkb": "IL18; IGIF", "gene_names_refseq": "IL-18; IL18", "protein_names_uniprotkb": "Interleukin-18; IFN-gamma-inducing factor; IL-1 gamma; IL-18; Interferon gamma-inducing factor; Interleukin-1 gamma", "protein_names_refseq": "IFN-gamma-inducing factor; IL-1 gamma; interferon gamma-inducing factor; interleukin 18 (interferon-gamma-inducing factor); interleukin-1 gamma; interleukin-18", "tax_id": 9823, "disease": "", "pathway": " (ssc:397057); (R-SSC-448706); (R-SSC-5620971); (R-SSC-9012546); (R-SSC-9960519); (R-SSC-9960525)", "pathway_count": 6, "publication_count": 5, "publication_id_list": "10803849;17079874;20380728;21682650;25036760", "class_list": "", "function": "Endometrial expression of CASP1 and IL18 associated with pregnancy establishment; alteration of CASP1 and IL18 following premature exposure of uterus to estrogen during early pregnancy may contribute to conceptus loss between Days 15 to 18 of pregnancy Publication Status: Online-Only, [RefSeq, PubMed]; IL-18 concentration in saliva was significantly increased during a 60-min acute immobilization stress in thirteen 5-month-old pigs. These results are the first evidence of a stress-related change of IL-18 in pig saliva., [RefSeq, PubMed]; Porcine IL-18 regulates anti-pig cellular rejection in C57BL/6 mice. Erratum:[Exp Mol Med. 2006 Dec 31;38(6):739], [RefSeq, PubMed]; Pro-inflammatory cytokine primarily involved in epithelial barrier repair, polarized T-helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells and natural killer (NK) cells. Involved in transduction of inflammation downstream of pyroptosis: its mature form is specifically released in the extracellular milieu by passing through the gasdermin-D (GSDMD) pore., [UniProtKB, UniProtKB]; Study reports that the monocyte-derived cytokines IL-12 and IL-18 act synergistically on porcine gammadelta T cells to induce IFN-gamma production. Additional stimuli such as the mitogen ConA and IL-2 are necessary to activate the cells for enhanced proliferation., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q1HDI4", "ec_number_list": "", "go_molecular_function": "GO:0045515 interleukin-18 receptor binding;GO:0005125 cytokine activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005829 cytosol", "go_biological_process": "GO:0001525 angiogenesis;GO:0006954 inflammatory response;GO:0006955 immune response;GO:0008284 positive regulation of cell population proliferation;GO:0050830 defense response to Gram-positive bacterium", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "O19073-1", "record_type": "protein" }, { "uniprot_canonical_ac": "O19175-1", "uniprot_id": "KC1A_PIG", "mass": 14633.0, "length": 125, "protein_name": "Casein kinase I isoform alpha", "gene_name": "CSNK1A1", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "CSNK1A1", "gene_names_refseq": "", "protein_names_uniprotkb": "Casein kinase I isoform alpha; 2.7.11.1; CK1; CKI-alpha", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "8672129", "class_list": "", "function": "Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at 'Ser-45' (By similarity). May phosphorylate PER1 and PER2 (By similarity). May play a role in segregating chromosomes during mitosis. May play a role in keratin cytoskeleton disassembly and thereby, it may regulate epithelial cell migration. Acts as a positive regulator of mTORC1 and mTORC2 signaling in response to nutrients by mediating phosphorylation of DEPTOR inhibitor (By similarity). Acts as an inhibitor of NLRP3 inflammasome assembly by mediating phosphorylation of NLRP3 (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004672 protein kinase activity;GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005813 centrosome;GO:0005819 spindle;GO:0016607 nuclear speck;GO:0000776 kinetochore", "go_biological_process": "GO:0006468 protein phosphorylation;GO:0051301 cell division;GO:0016055 Wnt signaling pathway;GO:0045104 intermediate filament cytoskeleton organization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "O19175-1", "record_type": "protein" }, { "uniprot_canonical_ac": "O46409-1", "uniprot_id": "APOA4_PIG", "mass": 43294.0, "length": 382, "protein_name": "Apolipoprotein A-IV", "gene_name": "APOA4", "organism": "Pig", "refseq_name": "apolipoprotein A-IV precursor", "refseq_ac": "NP_999553", "gene_names_uniprotkb": "APOA4", "gene_names_refseq": "APOA4", "protein_names_uniprotkb": "Apolipoprotein A-IV; Apo-AIV; ApoA-IV; Apolipoprotein A4", "protein_names_refseq": "apo-AIV; apoA-IV; apolipoprotein A-IV precursor; apolipoprotein A-IV", "tax_id": 9823, "disease": "", "pathway": " (ssc:397681)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "14697520;15878672;17556588;18777092;21127258", "class_list": "", "function": "APOA4 genes with SNPs, [RefSeq, PubMed]; Down-regulation of apolipoprotein A-I and A-IV messages in the liver may be mediated by interleukin 6 and tumor necrosis factor-alpha, [RefSeq, PubMed]; Hepatocyte nuclear factor 4 alpha (HNF-4 alpha)induces apoliprotein IV gene in response to dietary lipids in the intestine., [RefSeq, PubMed]; MTTP is regulated by apo A-IV in manner to promote increased packaging of triglyceride into chylomicron core, which may be important in neonatal fat absorption., [RefSeq, PubMed]; May have a role in chylomicrons and VLDL secretion and catabolism. Required for efficient activation of lipoprotein lipase by ApoC-II; potent activator of LCAT. Apoa-IV is a major component of HDL and chylomicrons., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A9LM22", "ec_number_list": "", "go_molecular_function": "GO:0005543 phospholipid binding;GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity;GO:0120020 cholesterol transfer activity", "go_cellular_component": "GO:0034364 high-density lipoprotein particle;GO:0034361 very-low-density lipoprotein particle;GO:0042627 chylomicron;GO:0034362 low-density lipoprotein particle;GO:1903561 extracellular vesicle", "go_biological_process": "GO:0008203 cholesterol metabolic process;GO:0033700 phospholipid efflux;GO:0042157 lipoprotein metabolic process;GO:0033344 cholesterol efflux;GO:0006950 response to stress", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "O46409-1", "record_type": "protein" }, { "uniprot_canonical_ac": "O62680-1", "uniprot_id": "CD59_PIG", "mass": 13790.0, "length": 123, "protein_name": "CD59 glycoprotein", "gene_name": "CD59", "organism": "Pig", "refseq_name": "CD59 glycoprotein precursor", "refseq_ac": "NP_999335", "gene_names_uniprotkb": "CD59", "gene_names_refseq": "CD59", "protein_names_uniprotkb": "CD59 glycoprotein; MAC-IP; MAC-inhibitory protein; MACIF; Membrane attack complex inhibition factor; Protectin", "protein_names_refseq": "CD59 glycoprotein precursor; CD59 glycoprotein; CD59 molecule (CD59 blood group); MAC-IP; MAC-inhibitory protein; MACIF; membrane attack complex inhibition factor; protectin", "tax_id": 9823, "disease": "", "pathway": " (ssc:397347); (R-SSC-204005); (R-SSC-5694530); (R-SSC-6798695); (R-SSC-6807878); (R-SSC-977606)", "pathway_count": 6, "publication_count": 4, "publication_id_list": "20636542;7533195;9558099;9808497", "class_list": "", "function": "Data demonstrate that the resistance of neonatal porcine Sertoli cells to human xenoantibody and complement-mediated lysis is associated with low expression of xenoantigen alpha-Gal and high production of the complement inhibitors clusterin and CD59., [RefSeq, PubMed]; Potent inhibitor of the complement membrane attack complex (MAC) action, which protects self-cells from damage during complement activation (PubMed:9558099, PubMed:9808497). Acts by binding to the beta-haipins of C8 (C8A and C8B) components of the assembling MAC, forming an intermolecular beta-sheet that prevents incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore (By similarity)., [UniProtKB, PubMed, PubMed, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q9TR76;Q9XT94", "ec_number_list": "", "go_molecular_function": "GO:0001848 complement binding;GO:0140311 protein sequestering activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0005886 plasma membrane;GO:0098552 side of membrane", "go_biological_process": "GO:0045087 innate immune response;GO:0045916 negative regulation of complement activation;GO:0001971 negative regulation of activation of membrane attack complex;GO:1903660 negative regulation of complement-dependent cytotoxicity", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "O62680-1", "record_type": "protein" }, { "uniprot_canonical_ac": "O62697-1", "uniprot_id": "DFB4A_PIG", "mass": 7066.0, "length": 64, "protein_name": "Defensin beta 4A", "gene_name": "DEFB4A", "organism": "Pig", "refseq_name": "beta-defensin 1 precursor", "refseq_ac": "NP_999003", "gene_names_uniprotkb": "DEFB4A; DEFB102; DEFB2; DEFB4", "gene_names_refseq": "PBD-1; PBD1", "protein_names_uniprotkb": "Defensin beta 4A; BD-2; Beta-defensin 2; Defensin, beta 2", "protein_names_refseq": "BD-1; beta-defensin 1 precursor; prepro-beta-defensin 1", "tax_id": 9823, "disease": "", "pathway": " (ssc:396819); (R-SSC-1461957)", "pathway_count": 2, "publication_count": 5, "publication_id_list": "10446172;16552064;23065293;23220638;9537511", "class_list": "", "function": "Exhibits antimicrobial activity against Gram-negative bacteria and Gram-positive bacteria, with highest activity against Gram-negative bacteria. Antimicrobial activity against P.aeruginosa seems to be salt-sensitive and is reduced with high salt concentrations greater than 25 mM. Also exhibits antimicrobial activity against the yeast C.albicans. Permeabilizes C.albicans cell membranes via targeting plasma membrane lipid phosphatidylinositol 4,5-bisphosphate (PIP2), thereby leading to cell fragmentation and cell death. Acts as a ligand for C-C chemokine receptor CCR6. Binds to CCR6 and induces chemotactic activity of CCR6-expressing cells, such as immature dendritic cells and memory T cells., [UniProtKB, UniProtKB]; PBD1 showed low hemolytic activity and high thermal stability. These properties are relevant for the biotechnological applications of the peptide., [RefSeq, PubMed]; Presence of beta-defensin 1 in the upper respiratory tract is associated with resistance against respiratory infection with Bordetella pertussis in older piglets, [RefSeq, PubMed]; Zinc sulfate and L-isoleucine induce beta defensin expression in a porcine cell line., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0042056 chemoattractant activity;GO:0042802 identical protein binding;GO:0031731 CCR6 chemokine receptor binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0016020 membrane;GO:0097225 sperm midpiece;GO:1990742 microvesicle", "go_biological_process": "GO:0019722 calcium-mediated signaling;GO:0050829 defense response to Gram-negative bacterium;GO:0050830 defense response to Gram-positive bacterium;GO:0060326 cell chemotaxis;GO:0042742 defense response to bacterium", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "O62697-1", "record_type": "protein" }, { "uniprot_canonical_ac": "O62787-1", "uniprot_id": "GTR3_PIG", "mass": 53963.0, "length": 493, "protein_name": "Solute carrier family 2, facilitated glucose transporter member 3", "gene_name": "SLC2A3", "organism": "Pig", "refseq_name": "solute carrier family 2, facilitated glucose transporter member 3", "refseq_ac": "XP_020948051", "gene_names_uniprotkb": "SLC2A3; GLUT3", "gene_names_refseq": "GLUT-3; GLUT3; SLC2A3", "protein_names_uniprotkb": "Solute carrier family 2, facilitated glucose transporter member 3; GLUT-3; Glucose transporter type 3, brain", "protein_names_refseq": "Glucose transporter type 3, brain; glucose transporter type 3; sodium- and chloride-dependent taurine transporter; solute carrier family 2 (facilitated glucose transporter), member 3; solute carrier family 2, facilitated glucose transporter member 3", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-189200); (R-SSC-196836); (R-SSC-6798695)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "41018975", "class_list": "", "function": "Facilitative glucose transporter. Can also mediate the uptake of various other monosaccharides across the cell membrane. Mediates the uptake of glucose, 2-deoxyglucose, galactose, mannose, xylose and fucose, and probably also dehydroascorbate. Does not mediate fructose transport. Required for mesendoderm differentiation (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 1, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 1, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 1, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0033300 dehydroascorbic acid transmembrane transporter activity;GO:0005536 D-glucose binding;GO:0055056 D-glucose transmembrane transporter activity;GO:0005354 galactose transmembrane transporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane;GO:0043204 perikaryon;GO:0042995 cell projection", "go_biological_process": "GO:0070837 dehydroascorbic acid transport;GO:1904659 D-glucose transmembrane transport;GO:0015757 galactose transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "O62787-1", "record_type": "protein" }, { "uniprot_canonical_ac": "O62809-1", "uniprot_id": "OX2R_PIG", "mass": 50765.0, "length": 444, "protein_name": "Orexin receptor type 2", "gene_name": "HCRTR2", "organism": "Pig", "refseq_name": "orexin receptor type 2", "refseq_ac": "NP_001123423", "gene_names_uniprotkb": "HCRTR2", "gene_names_refseq": "HCRTR2", "protein_names_uniprotkb": "Orexin receptor type 2; Hypocretin receptor type 2; Ox-2-R; Ox2-R; Ox2R", "protein_names_refseq": "hypocretin receptor type 2; orexin receptor type 2; ox-2-R; ox2-R; ox2R", "tax_id": 9823, "disease": "", "pathway": " (ssc:397428); (R-SSC-389397); (R-SSC-416476)", "pathway_count": 3, "publication_count": 5, "publication_id_list": "19394166;20610868;20688107;21888930;32296386", "class_list": "", "function": "Data demonstrated the presence of OX1R and OX2R genes and proteins in the ovary of the pig and the impact of the hormonal milieu on the expression of both receptors., [RefSeq, PubMed]; Expression of OX1R and Ox2R in hypothalamus during oestrous cycle; evidence OX1R and OX2R mRNAs and proteins occur in hypothalamic structures engaged in control of reproduction; indicate dependence of OXR expression on endocrine reproductive state, [RefSeq, PubMed]; Findings provide the first evidence that orexin receptors 1 and 2 messenger RNAs and proteins occur in the pituitary of the pig and indicate the dependence of orexin receptor expression on the endocrine reproductive state, [RefSeq, PubMed]; G protein-coupled receptor that binds neuropeptides orexin-A and orexin-B, two neuropeptides derived from a common precursor, prepro-orexin. Upon neuropeptide ligand binding, HCRTR2 can couple with both G(q)/11 and G(i)/o heterotrimeric G proteins thereby initiating distinct downstream signaling cascades (By similarity). Involved in regulating the sleep-wake cycle. Contributes to central regulation of glucose homeostasis (By similarity)., [UniProtKB, UniProtKB, UniProtKB]; Immunoreactivity (IR) for both orexins A and B (OXA and OXB), and cognate receptors (OX1R and OX2R) were identified only in the excretory striated ducts of the MSG while acinar cells were not immunoreactive., [RefSeq, PubMed]; Pharmacological Characteristics of Porcine Orexin 2 Receptor and Mutants. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "Q2MK76", "ec_number_list": "", "go_molecular_function": "GO:0016499 orexin receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007218 neuropeptide signaling pathway;GO:0051480 regulation of cytosolic calcium ion concentration;GO:0032870 cellular response to hormone stimulus;GO:0042593 glucose homeostasis;GO:0007631 feeding behavior", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "O62809-1", "record_type": "protein" }, { "uniprot_canonical_ac": "O62839-1", "uniprot_id": "CATA_PIG", "mass": 59883.0, "length": 527, "protein_name": "Catalase", "gene_name": "CAT", "organism": "Pig", "refseq_name": "catalase", "refseq_ac": "NP_999466", "gene_names_uniprotkb": "CAT", "gene_names_refseq": "CAT", "protein_names_uniprotkb": "Catalase; 1.11.1.6", "protein_names_refseq": "catalase", "tax_id": 9823, "disease": "", "pathway": " (ssc:397568)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "19786062;7592879;9475954", "class_list": "", "function": "Catalyzes the degradation of hydrogen peroxide (H(2)O(2)) generated by peroxisomal oxidases to water and oxygen, thereby protecting cells from the toxic effects of hydrogen peroxide. Promotes growth of cells including T-cells, B-cells, myeloid leukemia cells, melanoma cells, mastocytoma cells and normal and transformed fibroblast cells., [UniProtKB, UniProtKB]; Effect of beta-naphthoflavone on catalase in various brain regions of pig is reported., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9TR38;Q9TR39", "ec_number_list": "", "go_molecular_function": "GO:0046872 metal ion binding;GO:0020037 heme binding;GO:0004096 catalase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005777 peroxisome;GO:0005782 peroxisomal matrix", "go_biological_process": "GO:0042542 response to hydrogen peroxide;GO:0051781 positive regulation of cell division;GO:0042744 hydrogen peroxide catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "O62839-1", "record_type": "protein" }, { "uniprot_canonical_ac": "O77591-1", "uniprot_id": "IMPA1_PIG", "mass": 30133.0, "length": 277, "protein_name": "Inositol monophosphatase 1", "gene_name": "IMPA1", "organism": "Pig", "refseq_name": "inositol monophosphatase 1", "refseq_ac": "NP_999381", "gene_names_uniprotkb": "IMPA1", "gene_names_refseq": "IMPA1", "protein_names_uniprotkb": "Inositol monophosphatase 1; 3.1.3.25; 3.1.3.94; D-galactose 1-phosphate phosphatase; IMP 1; IMPase 1; Inositol-1(or 4)-monophosphatase 1; Lithium-sensitive myo-inositol monophosphatase A1", "protein_names_refseq": "D-galactose 1-phosphate phosphatase; IMP 1; IMPase 1; inositol monophosphatase 1; inositol-1(or 4)-monophosphatase 1; lithium-sensitive myo-inositol monophosphatase A1; myo-inositol monophosphatase", "tax_id": 9823, "disease": "", "pathway": " (ssc:397425)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Phosphatase involved in the dephosphorylation of myo-inositol monophosphate to generate myo-inositol. Is also able to dephosphorylate scyllo-inositol-phosphate, myo-inositol 1,4-diphosphate, scyllo-inositol-1,3-diphosphate and scyllo-inositol-1,4-diphosphate. Also dephosphorylates in vitro other sugar-phosphates including D-galactose-1-phosphate, glucose-1-phosphate, glucose-6-phosphate, fructose-1-phosphate, beta-glycerophosphate and 2'-AMP. Responsible for the provision of inositol required for synthesis of phosphatidylinositol and polyphosphoinositides, and involved in maintaining normal brain function. Has been implicated as the pharmacological target for lithium Li(+) action in brain., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0031403 lithium ion binding;GO:0052834 inositol monophosphate phosphatase activity;GO:0000287 magnesium ion binding;GO:0030145 manganese ion binding;GO:0008934 inositol monophosphate 1-phosphatase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0006020 inositol metabolic process;GO:0007165 signal transduction;GO:0006021 inositol biosynthetic process;GO:0046854 phosphatidylinositol phosphate biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "O77591-1", "record_type": "protein" }, { "uniprot_canonical_ac": "O77638-1", "uniprot_id": "NFAC1_PIG", "mass": 88010.0, "length": 822, "protein_name": "Nuclear factor of activated T-cells, cytoplasmic 1", "gene_name": "NFATC1", "organism": "Pig", "refseq_name": "nuclear factor of activated T-cells, cytoplasmic 1", "refseq_ac": "NP_999326", "gene_names_uniprotkb": "NFATC1; NFAT2; NFATC", "gene_names_refseq": "NF-ATc1; NF-ATc; NFATC1; NFATc; NFATmac", "protein_names_uniprotkb": "Nuclear factor of activated T-cells, cytoplasmic 1; NF-ATc1; NF-ATc; NFAT transcription complex cytosolic component; NFATc1; NFATc; NFATmac", "protein_names_refseq": "NFAT transcription complex cytosolic component; nuclear factor of activated T-cells, cytoplasmic 1; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1; transcription factor NFATmac", "tax_id": 9823, "disease": "", "pathway": " (ssc:397318)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "9677199", "class_list": "", "function": "Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2 or IL-4 gene transcription. Also controls gene expression in embryonic cardiac cells. Could regulate not only the activation and proliferation but also the differentiation and programmed death of T-lymphocytes as well as lymphoid and non-lymphoid cells. Required for osteoclastogenesis and regulates many genes important for osteoclast differentiation and function., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005667 transcription regulator complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0033173 calcineurin-NFAT signaling cascade", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "O77638-1", "record_type": "protein" }, { "uniprot_canonical_ac": "O77666-1", "uniprot_id": "TRI26_PIG", "mass": 62778.0, "length": 545, "protein_name": "Tripartite motif-containing protein 26", "gene_name": "TRIM26", "organism": "Pig", "refseq_name": "tripartite motif-containing protein 26", "refseq_ac": "NP_001116681", "gene_names_uniprotkb": "TRIM26; ZNF173", "gene_names_refseq": "TRIM26; afp; znf173", "protein_names_uniprotkb": "Tripartite motif-containing protein 26; 2.3.2.27; Zinc finger protein 173", "protein_names_refseq": "acid finger protein; tripartite motif-containing protein 26; zinc finger protein 173", "tax_id": 9823, "disease": "", "pathway": " (ssc:100144460)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "11685460;33086712;35077707", "class_list": "", "function": "E3 ubiquitin-protein ligase which regulates the IFN-beta production and antiviral response downstream of various DNA-encoded pattern-recognition receptors (PRRs) (PubMed:33086712). Also plays a central role in determining the response to different forms of oxidative stress by controlling levels of DNA glycosylases NEIL1, NEIL3 and NTH1 that are involved in repair of damaged DNA. Promotes nuclear IRF3 ubiquitination and proteasomal degradation. Bridges together TBK1 and NEMO during the innate response to viral infection leading to the activation of TBK1. Positively regulates LPS-mediated inflammatory innate immune response by catalyzing the 'Lys-11'-linked polyubiquitination of TAB1 to enhance its activation and subsequent NF-kappa-B and MAPK signalings. In a manner independent of its catalytic activity, inhibits WWP2, a SOX2-directed E3 ubiquitin ligase, and thus protects SOX2 from polyubiquitination and proteasomal degradation. Ubiquitinates the histone acetyltransferase protein complex component PHF20 and thereby triggers its degradation in the nucleus after its recruitment by the histone demethylase KDM6B, serving as a scaffold protein. Upon induction by TGF-beta, ubiquitinates the TFIID component TAF7 for proteasomal degradation (By similarity). Induces ferroptosis by ubiquitinating SLC7A11, a critical protein for lipid reactive oxygen species (ROS) scavenging (By similarity). Inhibitis Porcine reproductive and respiratory syndrome virus-2 by catalyzing the 'Lys-48'-linked polyubiquitination of the nucleocapsid protein N (PubMed:35077707)., [UniProtKB, UniProtKB, PubMed, UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0046597 host-mediated suppression of symbiont invasion", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "O77666-1", "record_type": "protein" }, { "uniprot_canonical_ac": "O77683-1", "uniprot_id": "RND3_PIG", "mass": 27368.0, "length": 244, "protein_name": "Rho-related GTP-binding protein RhoE", "gene_name": "RND3", "organism": "Pig", "refseq_name": "rho-related GTP-binding protein RhoE", "refseq_ac": "NP_999461", "gene_names_uniprotkb": "RND3; ARHE; RHO8; RHOE", "gene_names_refseq": "Arhe; RND3", "protein_names_uniprotkb": "Rho-related GTP-binding protein RhoE; 3.6.5.2; Rho family GTPase 3; Rho-related GTP-binding protein Rho8; Rnd3", "protein_names_refseq": "Rho related protein Rnd3/Rho8; rho-related GTP-binding protein Rho8; rho-related GTP-binding protein RhoE; rho8", "tax_id": 9823, "disease": "", "pathway": " (ssc:397559)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "30723633", "class_list": "", "function": "Binds GTP but lacks intrinsic GTPase activity and is resistant to Rho-specific GTPase-activating proteins., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A287B402;A0A4X1TGM1", "ec_number_list": "", "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0019901 protein kinase binding", "go_cellular_component": "GO:0005829 cytosol;GO:0005886 plasma membrane", "go_biological_process": "GO:0007015 actin filament organization;GO:0007165 signal transduction;GO:0032956 regulation of actin cytoskeleton organization;GO:0007264 small GTPase-mediated signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "O77683-1", "record_type": "protein" }, { "uniprot_canonical_ac": "O77741-1", "uniprot_id": "NRAM1_PIG", "mass": 59012.0, "length": 538, "protein_name": "Natural resistance-associated macrophage protein 1", "gene_name": "SLC11A1", "organism": "Pig", "refseq_name": "natural resistance-associated macrophage protein 1", "refseq_ac": "NP_998986", "gene_names_uniprotkb": "SLC11A1; NRAMP1", "gene_names_refseq": "NRAMP1; SLC11A1", "protein_names_uniprotkb": "Natural resistance-associated macrophage protein 1; NRAMP 1; Solute carrier family 11 member 1", "protein_names_refseq": "NRAMP 1; natural resistance-associated macrophage protein 1; solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1", "tax_id": 9823, "disease": "", "pathway": " (ssc:396764)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "10678911;17654007;18407056;24757812;28362979;9027577", "class_list": "", "function": "A significant correlation between different genotypes of Nramp1 gene and immune function and production performance, [RefSeq, PubMed]; Genomic organization and polymorphisms detected by denaturing HPLC of porcine NRAMP1 gene are reported., [RefSeq, PubMed]; Macrophage-specific antiporter that fluxes metal ions in either direction against a proton gradient. Localized to late endosomal lysosomal membranes, delivers bivalent cations from the cytosol into these acidic compartments where they may directly affect antimicrobial activity. Involved in iron metabolism and host natural resistance to infection with intracellular parasites. Pathogen resistance involves sequestration of Fe(2+) and Mn(2+), cofactors of both prokaryotic and eukaryotic catalases and superoxide dismutases, not only to protect the macrophage against its own generation of reactive oxygen species, but to deny the cations to the pathogen for synthesis of its protective enzymes., [UniProtKB, UniProtKB]; Study shows that, before and after weaning, Nramp1 was highly expressed in digestive (stomach) and intestinal (duodenum, jejunum, and ileum) tissues, further indicating a genetic role in both immune regulation to compensate for weaning stress and enhanced development of intestinal immunity. Publication Status: Online-Only, [RefSeq, PubMed]; The frequency of allele B and A was 0.93 and 0.90 on a total of 180 and 205 pigs for the polymorphism in intron 1 and intron 2 of the Nramp1 gene respectively in a mixed population of hybrid and purebred pigs., [RefSeq, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "Q9N1Y2", "ec_number_list": "", "go_molecular_function": "GO:0005384 manganese ion transmembrane transporter activity;GO:0051139 metal cation:proton antiporter activity;GO:0005381 iron ion transmembrane transporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005765 lysosomal membrane;GO:0031902 late endosome membrane;GO:0030670 phagocytic vesicle membrane;GO:0010008 endosome membrane", "go_biological_process": "GO:0034755 iron ion transmembrane transport;GO:0032496 response to lipopolysaccharide;GO:0000165 MAPK cascade;GO:0006879 intracellular iron ion homeostasis;GO:0006826 iron ion transport", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "O77741-1", "record_type": "protein" }, { "uniprot_canonical_ac": "O79876-1", "uniprot_id": "COX1_PIG", "mass": 56958.0, "length": 514, "protein_name": "Cytochrome c oxidase subunit 1", "gene_name": "MT-CO1", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "MT-CO1; COI; COXI; MTCO1", "gene_names_refseq": "", "protein_names_uniprotkb": "Cytochrome c oxidase subunit 1; 7.1.1.9; Cytochrome c oxidase polypeptide I", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (ssc:808503); (R-SSC-5419276); (R-SSC-5628897); (R-SSC-611105); (R-SSC-9707564); (R-SSC-9837999); (R-SSC-9864848)", "pathway_count": 7, "publication_count": 3, "publication_id_list": "10433971;11428467;9732457", "class_list": "", "function": "Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9TDR4", "ec_number_list": "", "go_molecular_function": "GO:0046872 metal ion binding;GO:0020037 heme binding;GO:0004129 cytochrome-c oxidase activity", "go_cellular_component": "GO:0005743 mitochondrial inner membrane;GO:0045277 respiratory chain complex IV", "go_biological_process": "GO:0006119 oxidative phosphorylation;GO:0022904 respiratory electron transport chain;GO:0009060 aerobic respiration", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "O79876-1", "record_type": "protein" }, { "uniprot_canonical_ac": "O97504-1", "uniprot_id": "MC4R_PIG", "mass": 36947.0, "length": 332, "protein_name": "Melanocortin receptor 4", "gene_name": "MC4R", "organism": "Pig", "refseq_name": "melanocortin receptor 4", "refseq_ac": "NP_999338", "gene_names_uniprotkb": "MC4R", "gene_names_refseq": "MC4R", "protein_names_uniprotkb": "Melanocortin receptor 4; MC4-R", "protein_names_refseq": "MC4-R; melanocortin receptor 4; melanocortin-4 receptor MC4R", "tax_id": 9823, "disease": "", "pathway": " (ssc:397359); (R-SSC-375276)", "pathway_count": 2, "publication_count": 10, "publication_id_list": "10656927;16520310;16734684;16879346;16879362;23199214;24128088;26020871;31629472;32738077", "class_list": "", "function": "A polymorphism within the MC4R gene is associated with feed intake and increased growth., [RefSeq, PubMed]; A polymorphism within the MC4R gene is associated with the fat/meat ratio., [RefSeq, PubMed]; Characterization of polymorphisms in the MC4R gene in relation to growth and fat deposition., [RefSeq, PubMed]; Deletion of MC4R results in hyperphagia and increased body fat, ultimately leading to hepatic steatosis without atherogenic diet. Minipigs lacking MC4R exhibited hyperorexia, insulin resistance, hyperinsulinemia, disordered lipid metabolism and their livers accumulated significant amounts of fat., [RefSeq, PubMed]; G protein-coupled receptor that binds melanocyte-stimulating hormones (alpha- and beta-MSH) and corticotropin/ACTH, which are peptide products of the POMC precursor. Functions as a central component of the leptin-melanocortin pathway, which is essential for maintaining energy homeostasis. Upon activation, couples to G(s) protein, stimulating adenylate cyclase and the cAMP-dependent signaling pathway, which promotes anorexogenic signaling in the hypothalamus and contributes to a negative energy balance. Regulates food intake: activation by agonists suppresses appetite, whereas the antagonist Agouti-related protein/AGRP precludes agonist-induced signaling, thereby stimulating appetite. Modulates the firing activity of neurons in paraventricular nucleus (PVN) of the hypothalamus via alpha-MSH and AGRP regulation of inwardly rectifying potassium channel KCNJ13 closure, independently of G(s) signaling. In the PVN, also interacts with opsin 3/OPN3, which couples to G(i/o) proteins to inhibit MC4R-mediated cAMP signaling, thereby promoting food intake. In intestinal epithelial cells, contributes to inhibition of hepatic glucose production via nesfatin-1/NUCB2, leading to increased cAMP levels and glucagon-like peptide 1 (GLP-1) secretion. Interaction with MGRN1 displaces the G(s) protein, further decreasing MC4R signaling activity. Also activated by gamma-MSH, though with low potency., [UniProtKB, UniProtKB]; Results of associated analysis show that the polymorphism of MC4R gene was associated traits of back fat thickness (BF)., [RefSeq, PubMed]; Study did not find any significant associations for polymorphisms in insulin-like grwoth factor 2, GTP Binding Protein alpha Subunits, Gs and melanocortin receptor 4 genes with reproductive traits of Polish Landrace and Large White pigs, [RefSeq, PubMed]; The Asp298Asn polymorphism of melanocortin-4 receptor (MC4R) in pigs: evidence for its potential effects on MC4R constitutive activity and cell surface expression., [RefSeq, PubMed]; These results indicate that genetic selection against boar taint is possible using MC4R as a marker., [RefSeq, PubMed]; These results suggest that LEPR, MC4R, PIK3C3 and VRTN are useful markers for accurately predicting breeding values in Duroc pigs., [RefSeq, PubMed]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "Q2EF33;Q9N141;Q9N274", "ec_number_list": "", "go_molecular_function": "GO:0046872 metal ion binding;GO:0031625 ubiquitin protein ligase binding;GO:0004978 corticotropin receptor activity;GO:0042923 neuropeptide binding;GO:0004980 melanocyte-stimulating hormone receptor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0098804 non-motile cilium membrane", "go_biological_process": "GO:2000252 negative regulation of feeding behavior;GO:1903998 regulation of eating behavior;GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0045780 positive regulation of bone resorption;GO:0060259 regulation of feeding behavior", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "O97504-1", "record_type": "protein" }, { "uniprot_canonical_ac": "O97507-1", "uniprot_id": "FA12_PIG", "mass": 68012.0, "length": 616, "protein_name": "Coagulation factor XII", "gene_name": "F12", "organism": "Pig", "refseq_name": "coagulation factor XII precursor", "refseq_ac": "NP_999407", "gene_names_uniprotkb": "F12", "gene_names_refseq": "F12; FXII", "protein_names_uniprotkb": "Coagulation factor XII; 3.4.21.38; HAF; Hageman factor", "protein_names_refseq": "HAF; coagulation factor XII precursor; factor XII; hageman factor", "tax_id": 9823, "disease": "", "pathway": " (ssc:397474)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Factor XII is a serum glycoprotein that participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then trypsin cleaves it to beta-factor XIIa. Alpha-factor XIIa activates factor XI to factor XIa (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 6, "predicted_n_glycosites": 4, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 6, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004252 serine-type endopeptidase activity;GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005791 rough endoplasmic reticulum", "go_biological_process": "GO:0007596 blood coagulation;GO:0042730 fibrinolysis;GO:0031638 zymogen activation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "O97507-1", "record_type": "protein" }, { "uniprot_canonical_ac": "O97580-1", "uniprot_id": "SUCB1_PIG", "mass": 46259.0, "length": 425, "protein_name": "Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial", "gene_name": "SUCLA2", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "SUCLA2", "gene_names_refseq": "", "protein_names_uniprotkb": "Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; 6.2.1.-; 6.2.1.5; 6.2.1.9; A-SCS; ATP-specific succinyl-CoA synthetase subunit beta; Itaconyl--CoA ligase [ADP-forming] subunit beta; Malyl--CoA ligase [ADP-forming] subunit beta; SCS-betaA; Succinyl-CoA synthetase beta-A chain", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "9765291", "class_list": "", "function": "ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. Also able to act as an ATP-specific itaconyl- and malyl-CoA synthetase., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0004775 succinate-CoA ligase (ADP-forming) activity;GO:0050074 malate-CoA ligase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0042709 succinate-CoA ligase complex", "go_biological_process": "GO:0006099 tricarboxylic acid cycle;GO:0006104 succinyl-CoA metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "O97580-1", "record_type": "protein" }, { "uniprot_canonical_ac": "O97581-1", "uniprot_id": "LHX3_PIG", "mass": 41825.0, "length": 383, "protein_name": "LIM/homeobox protein Lhx3", "gene_name": "LHX3", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "LHX3", "gene_names_refseq": "", "protein_names_uniprotkb": "LIM/homeobox protein Lhx3; Homeobox protein LIM-3; Homeobox protein P-LIM; LIM homeobox protein 3", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "10195693", "class_list": "", "function": "Transcription factor (PubMed:10195693). Recognizes and binds to the consensus sequence motif 5'-AATTAATTA-3' in the regulatory elements of target genes, such as glycoprotein hormones alpha chain CGA and visual system homeobox CHX10, positively modulating transcription; transcription can be co-activated by LDB2 (By similarity). Synergistically enhances transcription from the prolactin promoter in cooperation with POU1F1/Pit-1 (PubMed:10195693). Required for the establishment of the specialized cells of the pituitary gland and the nervous system (By similarity). Involved in the development of interneurons and motor neurons in cooperation with LDB1 and ISL1 (By similarity)., [UniProtKB, UniProtKB, UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0008270 zinc ion binding;GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0006355 regulation of DNA-templated transcription;GO:0045893 positive regulation of DNA-templated transcription;GO:0030182 neuron differentiation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "O97581-1", "record_type": "protein" }, { "uniprot_canonical_ac": "O97969-1", "uniprot_id": "NPY5R_PIG", "mass": 50474.0, "length": 446, "protein_name": "Neuropeptide Y receptor type 5", "gene_name": "NPY5R", "organism": "Pig", "refseq_name": "neuropeptide Y receptor type 5", "refseq_ac": "XP_003129059", "gene_names_uniprotkb": "NPY5R; NPYR5", "gene_names_refseq": "NPY Y5; NPY5-R; NPY5R; NPYR5; NPYY5-R", "protein_names_uniprotkb": "Neuropeptide Y receptor type 5; NPY-Y5 receptor; NPY5-R; NPYY5-R; Y5 receptor", "protein_names_refseq": "NPY-Y5 receptor; neuropeptide Y receptor type 5; neuropeptide Y5 receptor", "tax_id": 9823, "disease": "", "pathway": " (ssc:100517770); (R-SSC-375276); (R-SSC-418594)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Receptor for neuropeptide Y and peptide YY. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. Seems to be associated with food intake. Could be involved in feeding disorders (By similarity)., [UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0001601 peptide YY receptor activity;GO:0001602 pancreatic polypeptide receptor activity", "go_cellular_component": "GO:0098982 GABA-ergic synapse;GO:0005886 plasma membrane;GO:0043005 neuron projection;GO:0098793 presynapse;GO:0097731 9+0 non-motile cilium", "go_biological_process": "GO:0007218 neuropeptide signaling pathway;GO:0007268 chemical synaptic transmission;GO:0003151 outflow tract morphogenesis;GO:0003214 cardiac left ventricle morphogenesis;GO:0099538 synaptic signaling via neuropeptide", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "O97969-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P00258-1", "uniprot_id": "ADX_PIG", "mass": 19932.0, "length": 186, "protein_name": "Adrenodoxin, mitochondrial", "gene_name": "FDX1", "organism": "Pig", "refseq_name": "adrenodoxin, mitochondrial precursor", "refseq_ac": "NP_999230", "gene_names_uniprotkb": "FDX1", "gene_names_refseq": "FDX1", "protein_names_uniprotkb": "Adrenodoxin, mitochondrial; Adrenal ferredoxin; Ferredoxin-1", "protein_names_refseq": "adrenal ferredoxin; adrenodoxin, mitochondrial precursor; adrenodoxin, mitochondrial", "tax_id": 9823, "disease": "", "pathway": " (ssc:397133); (R-SSC-1362409); (R-SSC-196108); (R-SSC-211976); (R-SSC-2395516); (R-SSC-9857492)", "pathway_count": 6, "publication_count": 2, "publication_id_list": "1536558;2553401", "class_list": "", "function": "Essential for the synthesis of various steroid hormones. Participates in the reduction of mitochondrial cytochrome P450 for steroidogenesis. Transfers electrons from adrenodoxin reductase to CYP11A1, a cytochrome P450 that catalyzes cholesterol side-chain cleavage. Does not form a ternary complex with adrenodoxin reductase and CYP11A1 but shuttles between the two enzymes to transfer electrons., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0009055 electron transfer activity;GO:0046872 metal ion binding;GO:0051537 2 iron, 2 sulfur cluster binding", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0008203 cholesterol metabolic process;GO:0042446 hormone biosynthetic process;GO:0006694 steroid biosynthetic process;GO:0022900 electron transport chain;GO:0140647 P450-containing electron transport chain", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "P00258-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P00377-1", "uniprot_id": "DYR_PIG", "mass": 21455.0, "length": 186, "protein_name": "Dihydrofolate reductase", "gene_name": "DHFR", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "DHFR", "gene_names_refseq": "", "protein_names_uniprotkb": "Dihydrofolate reductase; 1.5.1.3", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "500653", "class_list": "", "function": "Catalyzes the reduction of 7,8-dihydrofolate (DHF) to 5,6,7,8-tetrahydrofolate in a NADPH-dependent manner. Key enzyme in folate metabolism. Contributes to the nuclear and mitochondrial de novo thymidylate biosynthesis pathway. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. Binds its own mRNA and that of DHFR2., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004146 dihydrofolate reductase activity;GO:0003729 mRNA binding;GO:0050661 NADP binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005739 mitochondrion", "go_biological_process": "GO:0046654 tetrahydrofolate biosynthetic process;GO:0006730 one-carbon metabolic process;GO:0046655 folic acid metabolic process;GO:0031427 response to methotrexate;GO:0046653 tetrahydrofolate metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "P00377-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P00671-1", "uniprot_id": "RNAS1_PIG", "mass": 13804.0, "length": 124, "protein_name": "Ribonuclease pancreatic", "gene_name": "RNASE1", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "RNASE1; RNS1", "gene_names_refseq": "", "protein_names_uniprotkb": "Ribonuclease pancreatic; 4.6.1.18; RNase 1; RNase A", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 3, "publication_id_list": "11947109;4904878;5460946", "class_list": "", "function": "Endonuclease that catalyzes the cleavage of RNA on the 3' side of pyrimidine nucleotides. Acts on single-stranded and double-stranded RNA (By similarity)., [UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0016787 hydrolase activity;GO:0003676 nucleic acid binding;GO:0004540 RNA nuclease activity;GO:0004522 ribonuclease A activity", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "GO:0050830 defense response to Gram-positive bacterium", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "P00671-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P00999-1", "uniprot_id": "IACA_PIG", "mass": 7595.0, "length": 65, "protein_name": "Seminal plasma acrosin inhibitor A1", "gene_name": "", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "", "gene_names_refseq": "", "protein_names_uniprotkb": "Seminal plasma acrosin inhibitor A1", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Inhibits acrosin., [UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004867 serine-type endopeptidase inhibitor activity", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "P00999-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P01177-1", "uniprot_id": "NEU1_PIG", "mass": 12887.0, "length": 125, "protein_name": "Oxytocin-neurophysin 1", "gene_name": "OXT", "organism": "Pig", "refseq_name": "oxytocin-neurophysin 1 precursor", "refseq_ac": "NP_001161061", "gene_names_uniprotkb": "OXT", "gene_names_refseq": "OXT; oxytocin", "protein_names_uniprotkb": "Oxytocin-neurophysin 1; OT-NPI; Ocytocin", "protein_names_refseq": "OT-NPI; oxytocin, prepropeptide; oxytocin-neurophysin 1 precursor; oxytocin-neurophysin 1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100152272); (R-SSC-388479); (R-SSC-416476)", "pathway_count": 3, "publication_count": 3, "publication_id_list": "13022701;1971513;428540", "class_list": "", "function": "Carrier protein that binds to and transports oxytocin from the hypothalamus to the posterior pituitary gland, protecting it from degradation and facilitating its release., [UniProtKB, UniProtKB]; Neuropeptide hormone released by the posterior pituitary gland that plays a key role in social behavior and other biological processes, such as milk ejection (By similarity). Released in response to a variety of social cues and acts by binding to oxytocin receptor (OXTR), triggering signaling that modulates neural circuits by altering ion channel activity, changing intrinsic neuronal properties and modifying synaptic transmission (both excitatory and inhibitory) (By similarity). Central release (direct secretion in the brain) plays essential roles in social behavior, such as maternal care, social cognition and affiliative behaviors (By similarity). Stressful and anxiogenic stimuli promote release of oxytocin, which acts as a powerful modulator of anxiety- and stress-related behaviors (By similarity). Modulates neural circuits related to reward, fear and social approach, encouraging care and cooperation, but can also increase guilt or aggression towards out-groups (By similarity). Beyond its role in social behavior, plays a role in other processes, such as parturition, lactation or osteoblast differentiation, when released peripherally (secreted from the posterior pituitary gland into the bloodstream) (By similarity). Required for parturition and milk ejection by triggering and strengthening contraction of the smooth muscle of the uterus and mammary gland, respectively (By similarity). Promotes bone mass by stimulating bone formation by osteoblasts (By similarity)., [UniProtKB, UniProtKB, UniProtKB]; Precursor of oxytocin, a neurohypophyseal hormone that plays a key role in social interactions and neurophysin 1, its carrier protein., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005185 neurohypophyseal hormone activity;GO:0031855 oxytocin receptor binding;GO:0005184 neuropeptide hormone activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0030141 secretory granule", "go_biological_process": "GO:0002125 maternal aggressive behavior;GO:0035556 intracellular signal transduction;GO:0032094 response to food;GO:0009612 response to mechanical stimulus;GO:0070474 positive regulation of uterine smooth muscle contraction", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "P01177-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P01224-1", "uniprot_id": "TSHB_PIG", "mass": 15761.0, "length": 138, "protein_name": "Thyrotropin subunit beta", "gene_name": "TSHB", "organism": "Pig", "refseq_name": "thyrotropin subunit beta precursor", "refseq_ac": "NP_999533", "gene_names_uniprotkb": "TSHB", "gene_names_refseq": "TSH-BETA; TSHB", "protein_names_uniprotkb": "Thyrotropin subunit beta; TSH-B; TSH-beta; Thyroid-stimulating hormone subunit beta; Thyrotropin beta chain", "protein_names_refseq": "TSH-B; thyroid stimulating hormone beta subunit; thyrotropin beta chain; thyrotropin beta subunit; thyrotropin subunit beta precursor; thyrotropin subunit beta", "tax_id": 9823, "disease": "", "pathway": " (ssc:397658); (R-SSC-209822); (R-SSC-209968); (R-SSC-375281)", "pathway_count": 4, "publication_count": 3, "publication_id_list": "1245181;2473932;8880412", "class_list": "", "function": "Indispensable for the control of thyroid structure and metabolism., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 1, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 1, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 1, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005179 hormone activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P01224-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P01228-1", "uniprot_id": "FSHB_PIG", "mass": 14605.0, "length": 129, "protein_name": "Follitropin subunit beta", "gene_name": "FSHB", "organism": "Pig", "refseq_name": "follitropin subunit beta precursor", "refseq_ac": "NP_999040", "gene_names_uniprotkb": "FSHB", "gene_names_refseq": "FSH-beta; FSHB", "protein_names_uniprotkb": "Follitropin subunit beta; FSH-B; FSH-beta; Follicle-stimulating hormone beta subunit; Follitropin beta chain", "protein_names_refseq": "FSH-B; follicle stimulating hormone beta subunit; follicle stimulating hormone, beta polypeptide; follitropin beta chain; follitropin beta subunit; follitropin subunit beta precursor; follitropin subunit beta", "tax_id": 9823, "disease": "", "pathway": " (ssc:396895); (R-SSC-209822); (R-SSC-375281)", "pathway_count": 3, "publication_count": 9, "publication_id_list": "10690358;18065386;20466637;2174241;22134063;30178695;3129323;34248262;658036", "class_list": "", "function": "A allele of FSHbeta-1 locus in all the population and FSHbeta-2 locus in pigs of the first parity had the positive effective on TNB, NBA, and WB., [RefSeq, PubMed]; As in vitro experiments in the present study suggested that LHX2 regulated the expression of Fshbeta, it is possible that LHX2 controls FSH synthesis at the transcriptional level., [RefSeq, PubMed]; ESR(B), FSHbeta(B), CTNNAL1(G), miR-27a(A) allele was favorable for litter size traits. Furthermore, combined genetic effect analysis showed ESR(AA)FSHbeta(BB), ESR(AA)CTNNAL1(CG), ESR(AA)miR-27a(AA), FSHbeta(BB)CTNNAL1(CC), FSHbeta(BB)miR-27a(AA) and CTNNAL1(CG) miR-27a(AB) was the favorable combined genotype for litter size traits., [RefSeq, PubMed]; Evaluation of reproductive traits and ovarian and uterine morphology of sows with different genotypes for the estrogen receptor, prolactin receptor, and follicle-stimulating hormone subunit beta genes., [RefSeq, PubMed]; Results showed that the effects of FSHb, ESR, and PRLR genes were significant in the Tibet pig population, and the effective genotypes of the three genes for reproductive traits were BB, BB, and AA, respectively., [RefSeq, PubMed]; Together with the alpha chain CGA constitutes follitropin, the follicle-stimulating hormone, and provides its biological specificity to the hormone heterodimer. Binds FSHR, a G protein-coupled receptor, on target cells to activate downstream signaling pathways. Follitropin is involved in follicle development and spermatogenesis in reproductive organs., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "Q3LRP6", "ec_number_list": "", "go_molecular_function": "GO:0016913 follicle-stimulating hormone activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005737 cytoplasm;GO:0016914 follicle-stimulating hormone complex", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway;GO:0007179 transforming growth factor beta receptor signaling pathway;GO:0001541 ovarian follicle development;GO:0042699 follicle-stimulating hormone signaling pathway;GO:0010893 positive regulation of steroid biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P01228-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P01232-1", "uniprot_id": "LSHB_PIG", "mass": 14889.0, "length": 141, "protein_name": "Lutropin subunit beta", "gene_name": "LHB", "organism": "Pig", "refseq_name": "lutropin subunit beta precursor", "refseq_ac": "NP_999245", "gene_names_uniprotkb": "LHB", "gene_names_refseq": "LHB", "protein_names_uniprotkb": "Lutropin subunit beta; LH-B; LSH-B; LSH-beta; Luteinizing hormone subunit beta; Lutropin beta chain", "protein_names_refseq": "LH-B; LH-beta subunit; LSH-B; LSH-beta; Lutropin subunit beta; luteinizing hormone beta polypeptide; luteinizing hormone beta subunit; lutropin beta chain; lutropin subunit beta precursor", "tax_id": 9823, "disease": "", "pathway": " (ssc:397153); (R-SSC-193048); (R-SSC-193993); (R-SSC-209822); (R-SSC-375281); (R-SSC-8866910); (R-SSC-975578)", "pathway_count": 7, "publication_count": 5, "publication_id_list": "1701088;19212008;2744222;31905166;4770795", "class_list": "", "function": "Changes in the expression of genes encoding beta-LH and GnRH-R were also demonstrated across the estrous cycle in swine, [RefSeq, PubMed]; MiR-7 mediates the signaling pathway of NE affecting FSH and LH synthesis in pig pituitary., [RefSeq, PubMed]; Promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 1, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 1, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 1, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "Q7YRL0", "ec_number_list": "", "go_molecular_function": "GO:0005179 hormone activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0001541 ovarian follicle development;GO:0042700 luteinizing hormone signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P01232-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P01284-1", "uniprot_id": "VIP_PIG", "mass": 8539.0, "length": 75, "protein_name": "VIP peptides", "gene_name": "VIP", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "VIP", "gene_names_refseq": "", "protein_names_uniprotkb": "VIP peptides; Peptide histidine isoleucinamide 27; Vasoactive intestinal polypeptide", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 5, "publication_id_list": "1329741;2843830;4829446;4854585;6947244", "class_list": "", "function": "PHM-27 is a bioactive form from proteolysis of the same precursor protein, that causes vasodilation. It is a potent agonist of the calcitonin receptor CALCR, with similar efficacy as calcitonin., [UniProtKB, UniProtKB]; VIP is a neuropeptide involved in a diverse array of physiological processes through activating the PACAP subfamily of class B1 G protein-coupled receptors: VIP receptor 1 (VPR1) and VIP receptor 2 (VPR2). Abundantly expressed throughout the CNS and peripheral nervous systems where they primarily exert neuroprotective and immune modulatory roles (By similarity). Also causes vasodilation, lowers arterial blood pressure, stimulates myocardial contractility, increases glycogenolysis and relaxes the smooth muscle of trachea, stomach and gall bladder (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9TRN0", "ec_number_list": "", "go_molecular_function": "GO:0005184 neuropeptide hormone activity;GO:0005179 hormone activity;GO:0031891 type 1 vasoactive intestinal polypeptide receptor binding", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0048255 mRNA stabilization;GO:0032880 regulation of protein localization;GO:0045732 positive regulation of protein catabolic process;GO:0070459 prolactin secretion", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P01284-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P01304-1", "uniprot_id": "NPY_PIG", "mass": 8596.0, "length": 76, "protein_name": "Pro-neuropeptide Y", "gene_name": "NPY", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "NPY", "gene_names_refseq": "", "protein_names_uniprotkb": "Pro-neuropeptide Y; NPY; Neuropeptide tyrosine", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 4, "publication_id_list": "1576993;2153577;2372534;6957876", "class_list": "", "function": "Ligand for neuropeptide Y receptor type 1 (NPY1R) (PubMed:2153577). It also binds and activates neuropeptide Y receptor type 2 (NPY2R) (By similarity). Receptor binding induces adenylate cyclase-inhibiting G protein-coupled receptor signaling, resulting in inhibition of cAMP production. Receptor activation by NPY also leads to an increase of intracellular Ca(2+) levels. Is involved in the regulation of eating behaviour, acting as a stimulator of food intake (By similarity). Involved in the regulation of colonic antisecretory tone, and colonic contractility (By similarity)., [UniProtKB, UniProtKB, UniProtKB, PubMed, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9N0M5", "ec_number_list": "", "go_molecular_function": "GO:0005184 neuropeptide hormone activity;GO:0031841 neuropeptide Y receptor binding;GO:0160041 neuropeptide activity", "go_cellular_component": "GO:0098992 neuronal dense core vesicle;GO:0005615 extracellular space", "go_biological_process": "GO:0032100 positive regulation of appetite;GO:0007204 positive regulation of cytosolic calcium ion concentration;GO:0007218 neuropeptide signaling pathway;GO:0007631 feeding behavior;GO:0008343 adult feeding behavior", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P01304-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P01351-1", "uniprot_id": "GAST_PIG", "mass": 11558.0, "length": 104, "protein_name": "Gastrin", "gene_name": "GAST", "organism": "Pig", "refseq_name": "gastrin precursor", "refseq_ac": "NP_001004036", "gene_names_uniprotkb": "GAST; GAS", "gene_names_refseq": "GAST", "protein_names_uniprotkb": "Gastrin; G34; Gastrin-34", "protein_names_refseq": "gastrin precursor; preprogastrin", "tax_id": 9823, "disease": "", "pathway": " (ssc:445524)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "14248711;14248712;6930858;6951161;7530658", "class_list": "", "function": "Gastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes. It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005179 hormone activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway;GO:0032094 response to food", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P01351-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P01359-1", "uniprot_id": "TFF2_PIG", "mass": 13834.0, "length": 127, "protein_name": "Trefoil factor 2", "gene_name": "TFF2", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "TFF2; SML1", "gene_names_refseq": "", "protein_names_uniprotkb": "Trefoil factor 2; PSP; Pancreatic spasmolytic polypeptide; SP; Spasmolytic polypeptide", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 9, "publication_id_list": "1518804;15299636;1536842;2303034;2804132;2857575;8081739;8134374;8302836", "class_list": "", "function": "Inhibits gastrointestinal motility and gastric acid secretion. Could function as a structural component of gastric mucus, possibly by stabilizing glycoproteins in the mucus gel through interactions with carbohydrate side chains., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008083 growth factor activity;GO:0031723 CXCR4 chemokine receptor binding", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0060455 negative regulation of gastric acid secretion;GO:0070098 chemokine-mediated signaling pathway;GO:0030277 maintenance of gastrointestinal epithelium", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P01359-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P01965-1", "uniprot_id": "HBA_PIG", "mass": 15039.0, "length": 141, "protein_name": "Hemoglobin subunit alpha", "gene_name": "HBA", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "HBA", "gene_names_refseq": "", "protein_names_uniprotkb": "Hemoglobin subunit alpha; Alpha-globin; Hemoglobin alpha chain", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 3, "publication_id_list": "10713517;565742;7990139", "class_list": "", "function": "Hemopressin acts as an antagonist peptide of the cannabinoid receptor CNR1. Hemopressin-binding efficiently blocks cannabinoid receptor CNR1 and subsequent signaling., [UniProtKB, UniProtKB]; Involved in oxygen transport from the lung to the various peripheral tissues., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 8, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0019825 oxygen binding;GO:0005344 oxygen carrier activity", "go_cellular_component": "GO:0005833 hemoglobin complex;GO:0031838 haptoglobin-hemoglobin complex", "go_biological_process": "GO:0048821 erythrocyte development;GO:0015671 oxygen transport", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "P01965-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P02009-1", "uniprot_id": "HBAZ_PIG", "mass": 15403.0, "length": 141, "protein_name": "Hemoglobin subunit zeta", "gene_name": "", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "", "gene_names_refseq": "", "protein_names_uniprotkb": "Hemoglobin subunit zeta; Hemoglobin zeta chain; Zeta-globin", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "6724525", "class_list": "", "function": "The zeta chain is an alpha-type chain of mammalian embryonic hemoglobin., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0019825 oxygen binding;GO:0005344 oxygen carrier activity", "go_cellular_component": "GO:0005833 hemoglobin complex;GO:0031838 haptoglobin-hemoglobin complex", "go_biological_process": "GO:0048821 erythrocyte development;GO:0015671 oxygen transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "P02009-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P02101-1", "uniprot_id": "HBE_PIG", "mass": 16095.0, "length": 147, "protein_name": "Hemoglobin subunit epsilon", "gene_name": "HBE1", "organism": "Pig", "refseq_name": "hemoglobin subunit epsilon", "refseq_ac": "NP_999612", "gene_names_uniprotkb": "HBE1", "gene_names_refseq": "HBE1", "protein_names_uniprotkb": "Hemoglobin subunit epsilon; Epsilon-globin; Hemoglobin epsilon chain", "protein_names_refseq": "epsilon-globin; hemoglobin epsilon chain; hemoglobin subunit epsilon; hemoglobin, epsilon 1", "tax_id": 9823, "disease": "", "pathway": " (ssc:407067)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "6724525", "class_list": "", "function": "Hemoglobin epsilon chain is a beta-type chain found in early embryos., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q29039", "ec_number_list": "", "go_molecular_function": "GO:0046872 metal ion binding;GO:0020037 heme binding;GO:0031721 hemoglobin alpha binding;GO:0019825 oxygen binding;GO:0005344 oxygen carrier activity", "go_cellular_component": "GO:0005833 hemoglobin complex;GO:0031838 haptoglobin-hemoglobin complex", "go_biological_process": "GO:0048821 erythrocyte development;GO:0015671 oxygen transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "P02101-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P02475-1", "uniprot_id": "CRYAA_PIG", "mass": 19746.0, "length": 173, "protein_name": "Alpha-crystallin A chain", "gene_name": "CRYAA", "organism": "Pig", "refseq_name": "alpha-crystallin A chain", "refseq_ac": "XP_020924949", "gene_names_uniprotkb": "CRYAA", "gene_names_refseq": "CRYAA", "protein_names_uniprotkb": "Alpha-crystallin A chain", "protein_names_refseq": "alpha-crystallin A chain", "tax_id": 9823, "disease": "", "pathway": " (ssc:110256286)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Contributes to the transparency and refractive index of the lens. Acts as a chaperone, preventing aggregation of various proteins under a wide range of stress conditions. Required for the correct formation of lens intermediate filaments as part of a complex composed of BFSP1, BFSP2 and CRYAA., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0042802 identical protein binding;GO:0046872 metal ion binding;GO:0051082 unfolded protein binding;GO:0005212 structural constituent of eye lens", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0032991 protein-containing complex", "go_biological_process": "GO:0032387 negative regulation of intracellular transport;GO:0043066 negative regulation of apoptotic process;GO:0007601 visual perception;GO:0050821 protein stabilization;GO:0009408 response to heat", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "P02475-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P04087-1", "uniprot_id": "INHA_PIG", "mass": 39190.0, "length": 364, "protein_name": "Inhibin alpha chain", "gene_name": "INHA", "organism": "Pig", "refseq_name": "inhibin alpha chain precursor", "refseq_ac": "NP_999354", "gene_names_uniprotkb": "INHA", "gene_names_refseq": "INHA", "protein_names_uniprotkb": "Inhibin alpha chain", "protein_names_refseq": "Inhibin alpha chain; inhibin alpha chain precursor; inhibin alpha subunit", "tax_id": 9823, "disease": "", "pathway": " (ssc:397386); (R-SSC-1502540); (R-SSC-201451); (R-SSC-209822); (R-SSC-9839406)", "pathway_count": 5, "publication_count": 8, "publication_id_list": "16879365;2417121;26097017;26208435;26521695;28082104;3016724;34502034", "class_list": "", "function": "CircRNA-Mediated Inhibin-Activin Balance Regulation in Ovarian Granulosa Cell Apoptosis and Follicular Atresia. Publication Status: Online-Only, [RefSeq, PubMed]; Data suggest that, in granulosa cells, inhibin alpha-subunit is involved in regulation of cell proliferation, extracellular matrix remodeling, oogenesis, and ovulation. These studies were conducted in China and involved transcriptome sequencing analysis in cultured granulosa cells (from slaughterhouse pigs) exposed in vitro to a neutralizing anti-inhibin alpha-subunit antibody., [RefSeq, PubMed]; Inhibin A is a dimer of alpha/INHA and beta-A/INHBA that functions as a feedback regulator in the hypothalamic-pituitary-gonadal (HPG) axis. Inhibits the secretion of FSH from the anterior pituitary gland by acting on pituitary gonadotrope cells. Antagonizes activin A by binding to the proteoglycan, betaglycan, and forming a stable complex with and, thereby, sequestering type II activin receptors while excluding type I receptor., [UniProtKB, UniProtKB]; Inhibin B is a dimer of alpha and beta-B that plays a crucial role in the regulation of the reproductive system by inhibiting the secretion of follicle-stimulating hormone (FSH) from the anterior pituitary gland. Thereby, maintains reproductive homeostasis in both males and females. Acts as a more potent suppressor of FSH release than inhibin A (By similarity). Functions as competitive receptor antagonist binding activin type II receptors with high affinity in the presence of the TGF-beta type III coreceptor/TGFBR3L (By similarity)., [UniProtKB, UniProtKB, UniProtKB]; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins., [UniProtKB, UniProtKB]; The c.-42G>A and c.3222G>A polymorphisms in the INHA gene are significantly associated with follicular cysts in sows., [RefSeq, PubMed]; The relationship of INHA insertion/deletion polymorphisms with follicular cysts was investigated, [RefSeq, PubMed]; This study provides evidence that the expressions of inhibin alpha subunit and betaglycan are inferior in cystic follicles, and this may be caused by the decrease in FSH in the presence of a cystic follicle., [RefSeq, PubMed]", "predicted_glycosites": 3, "predicted_n_glycosites": 2, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "Q2I0D4", "ec_number_list": "", "go_molecular_function": "GO:0005125 cytokine activity;GO:0005179 hormone activity;GO:0008083 growth factor activity;GO:0140311 protein sequestering activity", "go_cellular_component": "GO:0043512 inhibin A complex;GO:0005615 extracellular space;GO:0034673 inhibin-betaglycan-ActRII complex", "go_biological_process": "GO:0048731 system development;GO:0046880 regulation of follicle-stimulating hormone secretion;GO:0042127 regulation of cell population proliferation;GO:0007178 cell surface receptor protein serine/threonine kinase signaling pathway;GO:0032926 negative regulation of activin receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P04087-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P04163-1", "uniprot_id": "S10AA_PIG", "mass": 11075.0, "length": 96, "protein_name": "Protein S100-A10", "gene_name": "S100A10", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "S100A10", "gene_names_refseq": "", "protein_names_uniprotkb": "Protein S100-A10; Calpactin I light chain; Calpactin-1 light chain; Cellular ligand of annexin II; S100 calcium-binding protein A10; p10 protein; p11", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "2998764", "class_list": "", "function": "Because S100A10 induces the dimerization of ANXA2/p36, it may function as a regulator of protein phosphorylation in that the ANXA2 monomer is the preferred target (in vitro) of tyrosine-specific kinase., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0048306 calcium-dependent protein binding;GO:0044325 transmembrane transporter binding;GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "P04163-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P04175-1", "uniprot_id": "NCPR_PIG", "mass": 76833.0, "length": 678, "protein_name": "NADPH--cytochrome P450 reductase", "gene_name": "POR", "organism": "Pig", "refseq_name": "NADPH--cytochrome P450 reductase", "refseq_ac": "NP_001123431", "gene_names_uniprotkb": "POR", "gene_names_refseq": "POR", "protein_names_uniprotkb": "NADPH--cytochrome P450 reductase; 1.6.2.4; CPR; P450R", "protein_names_refseq": "CPR; NADPH--cytochrome P450 reductase; NADPH-cytochrome P-450 oxidoreductase; P450 (cytochrome) oxidoreductase; P450R", "tax_id": 9823, "disease": "", "pathway": " (ssc:100170114)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "3098240;3099837", "class_list": "", "function": "This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0050660 flavin adenine dinucleotide binding;GO:0010181 FMN binding;GO:0050661 NADP binding;GO:0003958 NADPH-hemoprotein reductase activity", "go_cellular_component": "GO:0005829 cytosol;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0009725 response to hormone;GO:0006809 nitric oxide biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "P04175-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P04185-1", "uniprot_id": "UROK_PIG", "mass": 49117.0, "length": 442, "protein_name": "Urokinase-type plasminogen activator", "gene_name": "PLAU", "organism": "Pig", "refseq_name": "urokinase-type plasminogen activator precursor", "refseq_ac": "NP_999110", "gene_names_uniprotkb": "PLAU", "gene_names_refseq": "PLAU; uPA", "protein_names_uniprotkb": "Urokinase-type plasminogen activator; 3.4.21.73; U-plasminogen activator; uPA", "protein_names_refseq": "U-plasminogen activator; Urokinase-type plasminogen activator; urinary plasminogen activator; urokinase-type plasminogen activator precursor", "tax_id": 9823, "disease": "", "pathway": " (ssc:396985)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "22177313;6096832", "class_list": "", "function": "Serine protease that cleaves the inactive precursor plasminogen at a specific Arg-Val peptide bond, converting it into active plasmin. Secreted as an inactive zymogen, it is recruited and activated at the cell surface through interaction with the urokinase plasminogen activator receptor (uPAR). Cell-surface activation enables localized, plasmin-dependent pericellular proteolysis, regulating extracellular matrix degradation in cell migration and tissue remodeling (By similarity). Also contributes to fibrinolysis and blood clot clearance by promoting plasmin generation (By similarity)., [UniProtKB, UniProtKB, UniProtKB]; The plasminogen/plasminogen activator/plasmin system is activated during gamete interaction and regulates the sperm entry into the oocyte., [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004252 serine-type endopeptidase activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0033628 regulation of cell adhesion mediated by integrin;GO:0042730 fibrinolysis;GO:0031639 plasminogen activation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "P04185-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P04416-1", "uniprot_id": "PA22_PIG", "mass": 13969.0, "length": 124, "protein_name": "Phospholipase A2, minor isoenzyme", "gene_name": "", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "", "gene_names_refseq": "", "protein_names_uniprotkb": "Phospholipase A2, minor isoenzyme; 3.1.1.4; Phosphatidylcholine 2-acylhydrolase", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "518908", "class_list": "", "function": "PA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005102 signaling receptor binding;GO:0005543 phospholipid binding;GO:0005509 calcium ion binding;GO:0004623 phospholipase A2 activity", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "GO:0016042 lipid catabolic process;GO:0050482 arachidonate secretion;GO:0046470 phosphatidylcholine metabolic process;GO:0046471 phosphatidylglycerol metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "P04416-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P04574-1", "uniprot_id": "CPNS1_PIG", "mass": 28068.0, "length": 266, "protein_name": "Calpain small subunit 1", "gene_name": "CAPNS1", "organism": "Pig", "refseq_name": "calpain small subunit 1", "refseq_ac": "NP_999483", "gene_names_uniprotkb": "CAPNS1; CAPN4", "gene_names_refseq": "CAPN4; CAPNS1", "protein_names_uniprotkb": "Calpain small subunit 1; CANP small subunit; CDPS; CSS1; Calcium-activated neutral proteinase small subunit; Calcium-dependent protease small subunit 1; Calcium-dependent protease small subunit; Calpain regulatory subunit", "protein_names_refseq": "CANP small subunit; CDPS; CSS1; calcium-activated neutral proteinase small subunit; calcium-dependent protease small subunit 1; calpain I light subunit; calpain regulatory subunit; calpain small subunit 1", "tax_id": 9823, "disease": "", "pathway": " (ssc:397587); (R-SSC-1474228); (R-SSC-6809371); (R-SSC-9856530); (R-SSC-9860927)", "pathway_count": 5, "publication_count": 4, "publication_id_list": "12684003;21680104;2994060;9228946", "class_list": "", "function": "Polymorphisms in PPARGC1A and CAPNS1 genes may affect meat quality traits., [RefSeq, PubMed]; Regulatory subunit of the calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Essential for embryonic development (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q8SPJ8", "ec_number_list": "", "go_molecular_function": "GO:0004198 calcium-dependent cysteine-type endopeptidase activity;GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0110158 calpain complex", "go_biological_process": "GO:0006508 proteolysis", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P04574-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P06348-1", "uniprot_id": "H1T_PIG", "mass": 22059.0, "length": 211, "protein_name": "Histone H1t", "gene_name": "H1-6", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "H1-6; H1FT", "gene_names_refseq": "", "protein_names_uniprotkb": "Histone H1t", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "6389534", "class_list": "", "function": "Testis-specific histone H1 that forms less compacted chromatin compared to other H1 histone subtypes. Formation of more relaxed chromatin may be required to promote chromatin architecture required for proper chromosome regulation during meiosis, such as homologous recombination. Histones H1 act as linkers that bind to nucleosomes and compact polynucleosomes into a higher-order chromatin configuration., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003690 double-stranded DNA binding;GO:0031492 nucleosomal DNA binding;GO:0030527 structural constituent of chromatin", "go_cellular_component": "GO:0005634 nucleus;GO:0000786 nucleosome", "go_biological_process": "GO:0007283 spermatogenesis;GO:0030154 cell differentiation;GO:0006334 nucleosome assembly;GO:0030261 chromosome condensation;GO:0045910 negative regulation of DNA recombination", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "P06348-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P08552-1", "uniprot_id": "NFM_PIG", "mass": 51985.0, "length": 455, "protein_name": "Neurofilament medium polypeptide", "gene_name": "NEFM", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "NEFM; NEF3", "gene_names_refseq": "", "protein_names_uniprotkb": "Neurofilament medium polypeptide; 160 kDa neurofilament protein; NF-M; Neurofilament 3; Neurofilament triplet M protein", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "6439558", "class_list": "", "function": "Neurofilaments usually contain three intermediate filament proteins: NEFL, NEFM, and NEFH which are involved in the maintenance of neuronal caliber. May additionally cooperate with the neuronal intermediate filament proteins PRPH and INA to form neuronal filamentous networks (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 8, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005200 structural constituent of cytoskeleton", "go_cellular_component": "GO:0030424 axon;GO:0005882 intermediate filament;GO:0099160 postsynaptic intermediate filament cytoskeleton", "go_biological_process": "GO:0033693 neurofilament bundle assembly", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "P08552-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P09571-1", "uniprot_id": "TRFE_PIG", "mass": 76968.0, "length": 696, "protein_name": "Serotransferrin", "gene_name": "TF", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "TF", "gene_names_refseq": "", "protein_names_uniprotkb": "Serotransferrin; Beta-1 metal-binding globulin; Siderophilin; Transferrin", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 4, "publication_id_list": "11752780;2065820;2328566;3419934", "class_list": "", "function": "Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 1, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 1, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 1, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008199 ferric iron binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005769 early endosome;GO:0005886 plasma membrane;GO:0055037 recycling endosome", "go_biological_process": "GO:0019731 antibacterial humoral response;GO:0006879 intracellular iron ion homeostasis;GO:0006826 iron ion transport;GO:0051241 negative regulation of multicellular organismal process", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P09571-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P09955-1", "uniprot_id": "CBPB1_PIG", "mass": 47381.0, "length": 416, "protein_name": "Carboxypeptidase B", "gene_name": "CPB1", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "CPB1; CPB", "gene_names_refseq": "", "protein_names_uniprotkb": "Carboxypeptidase B; 3.4.17.2", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (ssc:397341)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "10391940;1422143;1989878;1989879;2018774;2223783;4026847", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9XSP3", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0004181 metallocarboxypeptidase activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0031410 cytoplasmic vesicle", "go_biological_process": "GO:0006508 proteolysis", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P09955-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P0C596-1", "uniprot_id": "DUS29_PIG", "mass": 25132.0, "length": 222, "protein_name": "Dual specificity phosphatase 29", "gene_name": "DUSP29", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "DUSP29; DUPD1", "gene_names_refseq": "", "protein_names_uniprotkb": "Dual specificity phosphatase 29; 3.1.3.16; 3.1.3.48; Dual specificity phosphatase DUPD1", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues within the same substrate, with a preference for phosphotyrosine as a substrate (By similarity). Involved in the modulation of intracellular signaling cascades. In skeletal muscle regulates systemic glucose homeostasis by activating, AMPK, an energy sensor protein kinase. Affects MAP kinase signaling though modulation of the MAPK1/2 cascade in skeletal muscle promoting muscle cell differentiation, development and atrophy (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004722 protein serine/threonine phosphatase activity;GO:0008138 protein tyrosine/serine/threonine phosphatase activity;GO:0033549 MAP kinase phosphatase activity;GO:0004725 protein tyrosine phosphatase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0070373 negative regulation of ERK1 and ERK2 cascade;GO:0006470 protein dephosphorylation;GO:0042692 muscle cell differentiation;GO:0043409 negative regulation of MAPK cascade", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "P0C596-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P0CG68-1", "uniprot_id": "UBC_PIG", "mass": 59993.0, "length": 533, "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "UBC", "gene_names_refseq": "", "protein_names_uniprotkb": "Polyubiquitin-C", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (ssc:396966); (R-SSC-110312); (R-SSC-110314); (R-SSC-110320); (R-SSC-1169091); (R-SSC-1234176); (R-SSC-1253288); (R-SSC-1295596); (R-SSC-1358803); (R-SSC-174048); (R-SSC-174084); (R-SSC-174154); (R-SSC-174178); (R-SSC-174184); (R-SSC-179409); (R-SSC-182971); (R-SSC-187577); (R-SSC-195253); (R-SSC-202424); (R-SSC-209543); (R-SSC-209560); (R-SSC-2122948); (R-SSC-2173788); (R-SSC-2173791); (R-SSC-2173795); (R-SSC-2173796); (R-SSC-2467813); (R-SSC-2559582); (R-SSC-2672351); (R-SSC-2871837); (R-SSC-3134975); (R-SSC-349425); (R-SSC-3769402); (R-SSC-382556); (R-SSC-445989); (R-SSC-450302); (R-SSC-450321); (R-SSC-450408); (R-SSC-4608870); (R-SSC-4641257); (R-SSC-4641258); (R-SSC-4641263); (R-SSC-532668); (R-SSC-5357905); (R-SSC-5357956); (R-SSC-5358346); (R-SSC-5607761); (R-SSC-5607764); (R-SSC-5632684); (R-SSC-5654726); (R-SSC-5654727); (R-SSC-5654732); (R-SSC-5654733); (R-SSC-5655862); (R-SSC-5656121); (R-SSC-5656169); (R-SSC-5668541); (R-SSC-5675221); (R-SSC-5675482); (R-SSC-5676590); (R-SSC-5684264); (R-SSC-5685942); (R-SSC-5687128); (R-SSC-5689603); (R-SSC-5689877); (R-SSC-5689880); (R-SSC-5689896); (R-SSC-5689901); (R-SSC-5693537); (R-SSC-5693565); (R-SSC-5696394); (R-SSC-5696395); (R-SSC-5696397); (R-SSC-5696400); (R-SSC-6781823); (R-SSC-6782135); (R-SSC-6782210); (R-SSC-6783310); (R-SSC-6804756); (R-SSC-6804757); (R-SSC-6804760); (R-SSC-6807004); (R-SSC-68867); (R-SSC-68949); (R-SSC-69017); (R-SSC-69231); (R-SSC-69481); (R-SSC-69601); (R-SSC-75815); (R-SSC-8849469); (R-SSC-8852276); (R-SSC-8854050); (R-SSC-8856825); (R-SSC-8856828); (R-SSC-8863795); (R-SSC-8866427); (R-SSC-8866652); (R-SSC-8866654); (R-SSC-8939236); (R-SSC-8939902); (R-SSC-8941858); (R-SSC-8948747); (R-SSC-8948751); (R-SSC-8951664); (R-SSC-901032); (R-SSC-9020702); (R-SSC-9033241); (R-SSC-909733); (R-SSC-912631); (R-SSC-917729); (R-SSC-917937); (R-SSC-936440); (R-SSC-936964); (R-SSC-937039); (R-SSC-937041); (R-SSC-937042); (R-SSC-937072); (R-SSC-9645460); (R-SSC-9646399); (R-SSC-9648002); (R-SSC-9664873); (R-SSC-9706369); (R-SSC-9708530); (R-SSC-975144); (R-SSC-975163); (R-SSC-9755511); (R-SSC-9758274); (R-SSC-9766229); (R-SSC-9770562); (R-SSC-9824878); (R-SSC-983168); (R-SSC-9861718); (R-SSC-9929491); (R-SSC-9931269); (R-SSC-9931295); (R-SSC-9932298); (R-SSC-9954709); (R-SSC-9954716); (R-SSC-9958810); (R-SSC-9958825)", "pathway_count": 140, "publication_count": 1, "publication_id_list": "2824145", "class_list": "", "function": "Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair; Lys-11-linked is involved in ERAD (endoplasmic reticulum-associated degradation) and in cell-cycle regulation; Lys-29-linked is involved in proteotoxic stress response and cell cycle; Lys-33-linked is involved in kinase modification; Lys-48-linked is involved in protein degradation via the proteasome; Lys-63-linked is involved in endocytosis, DNA-damage responses as well as in signaling processes leading to activation of the transcription factor NF-kappa-B. Linear polymer chains formed via attachment by the initiator Met lead to cell signaling. Ubiquitin is usually conjugated to Lys residues of target proteins, however, in rare cases, conjugation to Cys or Ser residues has been observed. When polyubiquitin is free (unanchored-polyubiquitin), it also has distinct roles, such as in activation of protein kinases, and in signaling (By similarity). During ubiquitination, the acceptor ubiquitin is positioned in the active site via direct interaction with the E2 ubiquitin-conjugating enzymes such as UBE2R2 (By similarity). As a monoubiquitin, its C-terminal glycine is recognized as a C-degron by Cul2-RING (CRL2) E3 ubiquitin-protein ligase complexes (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "P02248;P02249;P02250;P62974;Q29120;Q29203;Q29252;Q91887;Q91888;Q95260", "ec_number_list": "", "go_molecular_function": "GO:0003735 structural constituent of ribosome;GO:0031386 protein tag activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005741 mitochondrial outer membrane;GO:0022626 cytosolic ribosome", "go_biological_process": "GO:0016567 protein ubiquitination;GO:0019941 modification-dependent protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "P0CG68-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P0DW16-1", "uniprot_id": "RBM20_PIG", "mass": 133295.0, "length": 1223, "protein_name": "RNA-binding protein 20", "gene_name": "RBM20", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "RBM20", "gene_names_refseq": "", "protein_names_uniprotkb": "RNA-binding protein 20; RNA-binding motif protein 20", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "33188278", "class_list": "", "function": "RNA-binding protein that acts as a regulator of mRNA splicing of a subset of genes encoding key structural proteins involved in cardiac development, such as TTN (Titin), CACNA1C, CAMK2D or PDLIM5/ENH (PubMed:33188278). Acts as a repressor of mRNA splicing: specifically binds the 5'UCUU-3' motif that is predominantly found within intronic sequences of pre-mRNAs, leading to the exclusion of specific exons in target transcripts (By similarity). RBM20-mediated exon skipping is hormone-dependent and is essential for TTN isoform transition in both cardiac and skeletal muscles (By similarity). RBM20-mediated exon skipping of TTN provides substrates for the formation of circular RNA (circRNAs) from the TTN transcripts (By similarity). Together with RBM24, promotes the expression of short isoforms of PDLIM5/ENH in cardiomyocytes (By similarity)., [UniProtKB, UniProtKB, UniProtKB, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 18, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0097157 pre-mRNA intronic binding;GO:0003729 mRNA binding;GO:0008270 zinc ion binding;GO:1990935 splicing factor binding", "go_cellular_component": "GO:0005634 nucleus;GO:0036464 cytoplasmic ribonucleoprotein granule", "go_biological_process": "GO:0006397 mRNA processing;GO:0008380 RNA splicing;GO:0043484 regulation of RNA splicing;GO:0048024 regulation of mRNA splicing, via spliceosome;GO:0060914 heart formation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "P0DW16-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P10859-1", "uniprot_id": "HPLN1_PIG", "mass": 40261.0, "length": 354, "protein_name": "Hyaluronan and proteoglycan link protein 1", "gene_name": "HAPLN1", "organism": "Pig", "refseq_name": "hyaluronan and proteoglycan link protein 1 precursor", "refseq_ac": "NP_001004028", "gene_names_uniprotkb": "HAPLN1; CRTL1", "gene_names_refseq": "HAPLN1", "protein_names_uniprotkb": "Hyaluronan and proteoglycan link protein 1; Cartilage-link protein; Cartilage-linking protein 1; Proteoglycan link protein", "protein_names_refseq": "cartilage-link protein; cartilage-linking protein 1; hyaluronan and proteoglycan link protein 1 precursor; link protein precursor (AA -15 to 339); proteoglycan link protein", "tax_id": 9823, "disease": "", "pathway": " (ssc:445513)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "2738916", "class_list": "", "function": "Stabilizes the aggregates of proteoglycan monomers with hyaluronic acid in the extracellular cartilage matrix., [UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005540 hyaluronic acid binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0045202 synapse;GO:0072534 perineuronal net", "go_biological_process": "GO:0007155 cell adhesion;GO:0007417 central nervous system development;GO:0001501 skeletal system development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "P10859-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P11493-1", "uniprot_id": "PP2AB_PIG", "mass": 33610.0, "length": 293, "protein_name": "Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform", "gene_name": "PPP2CB", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "PPP2CB", "gene_names_refseq": "", "protein_names_uniprotkb": "Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform; 3.1.3.16; PP2A-beta", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "2827745", "class_list": "", "function": "Catalytic subunit of protein phosphatase 2A (PP2A), a serine/threonine phosphatase involved in the regulation of a wide variety of enzymes, signal transduction pathways, and cellular events. PP2A can modulate the activity of phosphorylase B kinase, casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Part of the striatin-interacting phosphatase and kinase (STRIPAK) complexes. STRIPAK complexes have critical roles in protein (de)phosphorylation and are regulators of multiple signaling pathways including Hippo, MAPK, nuclear receptor and cytoskeleton remodeling. Different types of STRIPAK complexes are involved in a variety of biological processes such as cell growth, differentiation, apoptosis, metabolism and immune regulation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0046872 metal ion binding;GO:0004722 protein serine/threonine phosphatase activity", "go_cellular_component": "GO:0000922 spindle pole;GO:0005634 nucleus;GO:0005829 cytosol;GO:0000775 chromosome, centromeric region;GO:0090443 FAR/SIN/STRIPAK complex", "go_biological_process": "GO:0000278 mitotic cell cycle", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "P11493-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P12021-1", "uniprot_id": "MUCAP_PIG", "mass": 109616.0, "length": 1150, "protein_name": "Apomucin", "gene_name": "", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "", "gene_names_refseq": "", "protein_names_uniprotkb": "Apomucin; Mucin core protein", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 4, "publication_id_list": "2033060;2826455;3611111;9092502", "class_list": "", "function": "Apomucin is part of mucin, the major glycoprotein synthesized and secreted by mucous cells of the submaxillary gland. Its highly viscous aqueous solutions serve to lubricate the oral cavity and to protect it from the external environment., [UniProtKB]", "predicted_glycosites": 8, "predicted_n_glycosites": 6, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 31, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 31, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 31, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 39, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 3.6, "record_id": "P12021-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P12067-1", "uniprot_id": "LYSC1_PIG", "mass": 14668.0, "length": 128, "protein_name": "Lysozyme C-1", "gene_name": "", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "", "gene_names_refseq": "", "protein_names_uniprotkb": "Lysozyme C-1; 1,4-beta-N-acetylmuramidase C; 3.2.1.17", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "2504928", "class_list": "", "function": "Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003796 lysozyme activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0050829 defense response to Gram-negative bacterium;GO:0050830 defense response to Gram-positive bacterium;GO:0007586 digestion;GO:0031640 killing of cells of another organism", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "P12067-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P12068-1", "uniprot_id": "LYSC2_PIG", "mass": 16484.0, "length": 146, "protein_name": "Lysozyme C-2", "gene_name": "", "organism": "Pig", "refseq_name": "lysozyme C-1 precursor", "refseq_ac": "NP_999557", "gene_names_uniprotkb": "", "gene_names_refseq": "LYZS; LYZ", "protein_names_uniprotkb": "Lysozyme C-2; 1,4-beta-N-acetylmuramidase C; 3.2.1.17", "protein_names_refseq": "1,4-beta-N-acetylmuramidase C; lysozyme (renal amyloidosis); lysozyme C-1 precursor; lysozyme C-1; lysozyme C-2; lysozyme C-3", "tax_id": 9823, "disease": "", "pathway": " (ssc:100157211)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "2504928;8728388", "class_list": "", "function": "Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003796 lysozyme activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0050829 defense response to Gram-negative bacterium;GO:0050830 defense response to Gram-positive bacterium;GO:0007586 digestion;GO:0031640 killing of cells of another organism", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "P12068-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P12069-1", "uniprot_id": "LYSC3_PIG", "mass": 16711.0, "length": 148, "protein_name": "Lysozyme C-3", "gene_name": "", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "", "gene_names_refseq": "", "protein_names_uniprotkb": "Lysozyme C-3; 1,4-beta-N-acetylmuramidase C; 3.2.1.17", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-6798695); (R-SSC-6803157)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "2504928", "class_list": "", "function": "Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003796 lysozyme activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0050829 defense response to Gram-negative bacterium;GO:0050830 defense response to Gram-positive bacterium;GO:0007586 digestion;GO:0031640 killing of cells of another organism", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "P12069-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P12263-1", "uniprot_id": "FA8_PIG", "mass": 239305.0, "length": 2133, "protein_name": "Coagulation factor VIII", "gene_name": "F8", "organism": "Pig", "refseq_name": "coagulation factor VIII precursor", "refseq_ac": "NP_999332", "gene_names_uniprotkb": "F8; CF8", "gene_names_refseq": "F8", "protein_names_uniprotkb": "Coagulation factor VIII; Procoagulant component", "protein_names_refseq": "coagulation factor VIII precursor; coagulation factor VIII, procoagulant component (hemophilia A); factor VIII; procoagulant component", "tax_id": 9823, "disease": "", "pathway": " (ssc:397339)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "14983233;16513639;25589466;28237345;3016730;7510693;8274017", "class_list": "", "function": "Cupredoxin-like A1 subdomains in fVIII contain inter-species differences that are a result of selective pressure on the dissociation rate constant, [RefSeq, PubMed]; Factor VIII, along with calcium and phospholipid, acts as a cofactor for factor IXa when it converts factor X to the activated form, factor Xa., [UniProtKB]; It was concluded that VEGF and factor VIII are important growth factors associated with fetal development in pigs and are identified in all uterine segments., [RefSeq, PubMed]; Report Factor VIII organisation on nanodiscs with different lipid composition., [RefSeq, PubMed]; Thrombin stimulates transglutaminase activity in articular cartilage by directly cleaving factor XIII and by receptor-mediated up-regulation of factor XIII synthesis, [RefSeq, PubMed]", "predicted_glycosites": 15, "predicted_n_glycosites": 14, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 1, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 2, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 2, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 2, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 11, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 43, "disease_count": 0, "glyco_site_count": 16, "binding_glycan_count": 0, "secondary_ac_list": "Q95243", "ec_number_list": "", "go_molecular_function": "GO:0016491 oxidoreductase activity;GO:0005507 copper ion binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0031091 platelet alpha granule", "go_biological_process": "GO:0007597 blood coagulation, intrinsic pathway;GO:0006953 acute-phase response", "synthesized_glycan_count": 0, "hit_score": 5.3, "record_id": "P12263-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P13191-1", "uniprot_id": "ALAT1_PIG", "mass": 2218.0, "length": 20, "protein_name": "Alanine aminotransferase 1", "gene_name": "GPT", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "GPT; AAT1; GPT1", "gene_names_refseq": "", "protein_names_uniprotkb": "Alanine aminotransferase 1; 2.6.1.2; ALT1; GPT 1; Glutamate pyruvate transaminase 1; Glutamic--alanine transaminase 1; Glutamic--pyruvic transaminase 1", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 2, "publication_id_list": "11330835;465450", "class_list": "", "function": "Catalyzes the reversible transamination between alanine and 2-oxoglutarate to form pyruvate and glutamate. Participates in cellular nitrogen metabolism and also in liver gluconeogenesis starting with precursors transported from skeletal muscles (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004021 L-alanine:2-oxoglutarate aminotransferase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0042853 L-alanine catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "P13191-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P13222-1", "uniprot_id": "CLAT_PIG", "mass": 71731.0, "length": 641, "protein_name": "Choline O-acetyltransferase", "gene_name": "CHAT", "organism": "Pig", "refseq_name": "choline O-acetyltransferase", "refseq_ac": "NP_001001541", "gene_names_uniprotkb": "CHAT", "gene_names_refseq": "CHAT; ChoAcTase", "protein_names_uniprotkb": "Choline O-acetyltransferase; 2.3.1.6; CHOACTase; ChAT; Choline acetylase", "protein_names_refseq": "choline O-acetyltransferase; choline acetylase; choline acetyltransferase", "tax_id": 9823, "disease": "", "pathway": " (ssc:396896); (R-SSC-1483191); (R-SSC-264642)", "pathway_count": 3, "publication_count": 5, "publication_id_list": "19459441;2713713;3480542;3794697;8515278", "class_list": "", "function": "Catalyzes the reversible synthesis of acetylcholine (ACh) from acetyl CoA and choline at cholinergic synapses., [UniProtKB]; The results revealed broad coexistence of ChAT and CGRP in the spinal cord neurons which implies that the neurons synthesize and store ChAT and CGRP in their cell bodies., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004102 choline O-acetyltransferase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0045202 synapse;GO:0043005 neuron projection", "go_biological_process": "GO:0007274 neuromuscular synaptic transmission;GO:0008292 acetylcholine biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P13222-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P14057-1", "uniprot_id": "NFIL_PIG", "mass": 26162.0, "length": 231, "protein_name": "Nuclear factor 1", "gene_name": "NFI", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "NFI", "gene_names_refseq": "", "protein_names_uniprotkb": "Nuclear factor 1; CCAAT-box-binding transcription factor; CTF; NF-I; Nuclear factor I; TGGCA-binding protein", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 2, "publication_id_list": "2841167;3207762", "class_list": "", "function": "Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0006260 DNA replication;GO:0045893 positive regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "P14057-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P16164-1", "uniprot_id": "URIC_PIG", "mass": 35008.0, "length": 304, "protein_name": "Uricase", "gene_name": "UOX", "organism": "Pig", "refseq_name": "uricase precursor", "refseq_ac": "NP_999435", "gene_names_uniprotkb": "UOX", "gene_names_refseq": "UOX", "protein_names_uniprotkb": "Uricase; 1.7.3.3; Urate oxidase", "protein_names_refseq": "uricase precursor; uricase", "tax_id": 9823, "disease": "", "pathway": " (ssc:397510)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "2594778;3344434", "class_list": "", "function": "Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004846 urate oxidase activity", "go_cellular_component": "GO:0005777 peroxisome", "go_biological_process": "GO:0006145 purine nucleobase catabolic process;GO:0019628 urate catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "P16164-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P16611-1", "uniprot_id": "IBP3_PIG", "mass": 31690.0, "length": 293, "protein_name": "Insulin-like growth factor-binding protein 3", "gene_name": "IGFBP3", "organism": "Pig", "refseq_name": "insulin-like growth factor-binding protein 3 precursor", "refseq_ac": "NP_001005156", "gene_names_uniprotkb": "IGFBP3", "gene_names_refseq": "IGFBP-3; IGFBP3", "protein_names_uniprotkb": "Insulin-like growth factor-binding protein 3; IBP-3; IGF-binding protein 3; IGFBP-3", "protein_names_refseq": "IBP-3; IGF-binding protein 3; insulin-like growth factor-binding protein 3 precursor", "tax_id": 9823, "disease": "", "pathway": " (ssc:448812)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "12553871;14715717;1688850;1722398;19189208;21353438;21570979;21652730;37922860", "class_list": "", "function": "Allelic frequency of TAT in Chinese breeds was over 50%; allelic frequency of GGC was over 50% in all European breeds. TAT/TAT pigs scored higher in meat color than GGC/GGC pigs. results implied that IGFBP-3 may affect meat quality & carcass traits., [RefSeq, PubMed]; Even though LRP-1 mRNA and protein levels were dramatically reduced in LRP-1-silenced L6 cells compared with mock-silenced controls, rpIGFPB-3 suppressed proliferation rate to the same extent in both LRP-1-silenced and mock-silenced cultures., [RefSeq, PubMed]; IGF-I, IGF-II, and IGFBP-3 mRNA were positively correlated with IGF-IR from 50E to 180D, suggesting that the expression of IGF-system genes exhibits specific developmental patterns in the skeletal muscle tissues., [RefSeq, PubMed]; Increased oxidative stress from high glucose enhances IGFBP-3 expression, inducing apoptosis, [RefSeq, PubMed]; Multifunctional protein that plays a critical role in regulating the availability of IGFs such as IGF1 and IGF2 to their receptors and thereby regulates IGF-mediated cellular processes including proliferation, differentiation, and apoptosis in a cell-type specific manner. Also exhibits IGF-independent antiproliferative and apoptotic effects mediated by its receptor TMEM219/IGFBP-3R. Inhibits the positive effect of humanin on insulin sensitivity. Promotes testicular germ cell apoptosis. Acts via LRP-1/alpha2M receptor, also known as TGF-beta type V receptor, to mediate cell growth inhibition independent of IGF1. Mechanistically, induces serine-specific dephosphorylation of IRS1 or IRS2 upon ligation to its receptor, leading to the inhibitory cascade. In the nucleus, interacts with transcription factors such as retinoid X receptor-alpha/RXRA to regulate transcriptional signaling and apoptosis., [UniProtKB, UniProtKB]; Porcine IGFBP3 promotes porcine circovirus type 2 replication via PERK/eIF2alpha mediated DNA damage., [RefSeq, PubMed]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "Q6S6K2;Q9TTI0", "ec_number_list": "", "go_molecular_function": "GO:0001968 fibronectin binding;GO:0008160 protein tyrosine phosphatase activator activity;GO:0031994 insulin-like growth factor I binding;GO:0031995 insulin-like growth factor II binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005634 nucleus", "go_biological_process": "GO:0043065 positive regulation of apoptotic process;GO:0006915 apoptotic process;GO:0032868 response to insulin;GO:0045663 positive regulation of myoblast differentiation;GO:0043567 regulation of insulin-like growth factor receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P16611-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P16708-1", "uniprot_id": "UFAP_PIG", "mass": 47760.0, "length": 417, "protein_name": "Uteroferrin-associated protein", "gene_name": "", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "", "gene_names_refseq": "", "protein_names_uniprotkb": "Uteroferrin-associated protein; UFAP", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "2342477", "class_list": "", "function": "", "predicted_glycosites": 4, "predicted_n_glycosites": 4, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004867 serine-type endopeptidase inhibitor activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0007565 female pregnancy", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "P16708-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P17306-1", "uniprot_id": "STP1_PIG", "mass": 6424.0, "length": 55, "protein_name": "Spermatid nuclear transition protein 1", "gene_name": "TNP1", "organism": "Pig", "refseq_name": "spermatid nuclear transition protein 1", "refseq_ac": "XP_003133695", "gene_names_uniprotkb": "TNP1", "gene_names_refseq": "STP-1; TNP1; TP-1", "protein_names_uniprotkb": "Spermatid nuclear transition protein 1; STP-1; TP-1", "protein_names_refseq": "spermatid nuclear transition protein 1; transition protein 1 (during histone to protamine replacement)", "tax_id": 9823, "disease": "", "pathway": " (ssc:100513764)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "1627265;2777004;8019440", "class_list": "", "function": "Plays a key role in the replacement of histones to protamine in the elongating spermatids of mammals. In condensing spermatids, loaded onto the nucleosomes, where it promotes the recruitment and processing of protamines, which are responsible for histone eviction., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0001673 male germ cell nucleus;GO:0000786 nucleosome", "go_biological_process": "GO:0019953 sexual reproduction;GO:0006338 chromatin remodeling;GO:0030317 flagellated sperm motility;GO:0045892 negative regulation of DNA-templated transcription;GO:0007286 spermatid development", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "P17306-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P17630-1", "uniprot_id": "TCO1_PIG", "mass": 47095.0, "length": 417, "protein_name": "Transcobalamin-1", "gene_name": "TCN1", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "TCN1", "gene_names_refseq": "", "protein_names_uniprotkb": "Transcobalamin-1; Cobalophilin; Haptocorrin; Protein R; TC I; TC-1; TCI; Transcobalamin I", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "2331993", "class_list": "", "function": "Binds vitamin B12 with femtomolar affinity and protects it from the acidic environment of the stomach (By similarity). Binds to cobalamin and to cobalamin analogs such as cobinamide., [UniProtKB]", "predicted_glycosites": 8, "predicted_n_glycosites": 8, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 8, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0031419 cobalamin binding", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0015889 cobalamin transport;GO:0006824 cobalt ion transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "P17630-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P18137-1", "uniprot_id": "LALBA_PIG", "mass": 16174.0, "length": 141, "protein_name": "Alpha-lactalbumin", "gene_name": "LALBA", "organism": "Pig", "refseq_name": "alpha-lactalbumin precursor", "refseq_ac": "NP_999525", "gene_names_uniprotkb": "LALBA", "gene_names_refseq": "LALBA", "protein_names_uniprotkb": "Alpha-lactalbumin; Lactose synthase B protein", "protein_names_refseq": "alpha-lactalbumin precursor; alpha-lactalbumin; lactose synthase B protein", "tax_id": 9823, "disease": "", "pathway": " (ssc:397647); (R-SSC-5653890)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "1537566;2222864", "class_list": "", "function": "Regulatory subunit of lactose synthase, changes the substrate specificity of galactosyltransferase in the mammary gland making glucose a good acceptor substrate for this enzyme. This enables LS to synthesize lactose, the major carbohydrate component of milk. In other tissues, galactosyltransferase transfers galactose onto the N-acetylglucosamine of the oligosaccharide chains in glycoproteins., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005509 calcium ion binding;GO:0003796 lysozyme activity;GO:0004461 lactose synthase activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0032991 protein-containing complex", "go_biological_process": "GO:0050829 defense response to Gram-negative bacterium;GO:0050830 defense response to Gram-positive bacterium;GO:0005989 lactose biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "P18137-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P19130-1", "uniprot_id": "FRIH_PIG", "mass": 21045.0, "length": 181, "protein_name": "Ferritin heavy chain", "gene_name": "FTH1", "organism": "Pig", "refseq_name": "ferritin heavy chain", "refseq_ac": "NP_999140", "gene_names_uniprotkb": "FTH1; FTH", "gene_names_refseq": "FTH1", "protein_names_uniprotkb": "Ferritin heavy chain; 1.16.3.1; Ferritin H subunit", "protein_names_refseq": "ferritin H subunit; ferritin heavy chain", "tax_id": 9823, "disease": "", "pathway": " (ssc:397030)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "26333394;27030984;29844394;3688879", "class_list": "", "function": "(Microbial infection) Is unable to assume its function upon interaction with viral proteins, thereby increasing Fe concentration in the cytoplasm. This would inhibit the accumulation of reactive oxygen in host cells, leading to reduced apoptosis and increasing the survival of virus infected cell., [UniProtKB, PubMed]; Stores iron in a soluble, non-toxic, readily available form (By similarity). Important for iron homeostasis (By similarity). Has ferroxidase activity (By similarity). Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation (By similarity). Also plays a role in delivery of iron to cells (By similarity). Mediates iron uptake in capsule cells of the developing kidney (By similarity). Delivery to lysosomes is mediated by the cargo receptor NCOA4 for autophagic degradation and release of iron (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "P19131", "ec_number_list": "", "go_molecular_function": "GO:0008198 ferrous iron binding;GO:0004322 ferroxidase activity;GO:0008199 ferric iron binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005764 lysosome;GO:0031410 cytoplasmic vesicle;GO:0005776 autophagosome", "go_biological_process": "GO:0006879 intracellular iron ion homeostasis;GO:0006826 iron ion transport;GO:0110076 negative regulation of ferroptosis", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P19130-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P20460-1", "uniprot_id": "IF2A_PIG", "mass": 36108.0, "length": 315, "protein_name": "Eukaryotic translation initiation factor 2 subunit 1", "gene_name": "EIF2S1", "organism": "Pig", "refseq_name": "eukaryotic translation initiation factor 2 subunit 1", "refseq_ac": "XP_001928374", "gene_names_uniprotkb": "EIF2S1; EIF2A", "gene_names_refseq": "EIF2A; EIF2S1; eIF-2-alpha; eIF-2A; eIF-2alpha", "protein_names_uniprotkb": "Eukaryotic translation initiation factor 2 subunit 1; Eukaryotic translation initiation factor 2 subunit alpha; eIF-2-alpha; eIF-2A; eIF-2alpha; eIF2-alpha", "protein_names_refseq": "eIF2-alpha; eukaryotic translation initiation factor 2 subunit 1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100155472)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Member of the eIF2 complex that functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S pre-initiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF2 and release of an eIF2-GDP binary complex. In order for eIF2 to recycle and catalyze another round of initiation, the GDP bound to eIF2 must exchange with GTP by way of a reaction catalyzed by eIF2B. EIF2S1/eIF2-alpha is a key component of the integrated stress response (ISR), required for adaptation to various stress: phosphorylation by metabolic-stress sensing protein kinases (EIF2AK1/HRI, EIF2AK2/PKR, EIF2AK3/PERK and EIF2AK4/GCN2) in response to stress converts EIF2S1/eIF2-alpha in a global protein synthesis inhibitor, leading to a attenuation of cap-dependent translation, while concomitantly initiating the preferential translation of ISR-specific mRNAs, such as the transcriptional activators ATF4 and QRICH1, and hence allowing ATF4- and QRICH1-mediated reprogramming. EIF2S1/eIF2-alpha also acts as an activator of mitophagy in response to mitochondrial damage: phosphorylation by EIF2AK1/HRI promotes relocalization to the mitochondrial surface, thereby triggering PRKN-independent mitophagy (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A4X1U6Q4", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding;GO:0043022 ribosome binding;GO:0160296 cap-dependent translation initiation factor activity;GO:0160297 IRES-mediated translation initiation factor activity;GO:0003743 translation initiation factor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005739 mitochondrion;GO:0005829 cytosol;GO:0045202 synapse;GO:0010494 cytoplasmic stress granule", "go_biological_process": "GO:0034599 cellular response to oxidative stress;GO:0036499 PERK-mediated unfolded protein response;GO:0000423 mitophagy;GO:0034976 response to endoplasmic reticulum stress;GO:0034198 cellular response to amino acid starvation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "P20460-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P21999-1", "uniprot_id": "NFIC_PIG", "mass": 55462.0, "length": 506, "protein_name": "Nuclear factor 1 C-type", "gene_name": "NFIC", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "NFIC; NFI", "gene_names_refseq": "", "protein_names_uniprotkb": "Nuclear factor 1 C-type; CCAAT-box-binding transcription factor; CTF; NF-I/C; NF1-C; NFI-C; Nuclear factor 1/C; Nuclear factor I/C; TGGCA-binding protein", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "2513876", "class_list": "", "function": "Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 14, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0006260 DNA replication;GO:0045893 positive regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "P21999-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P22298-1", "uniprot_id": "SLPI_PIG", "mass": 13919.0, "length": 129, "protein_name": "Antileukoproteinase", "gene_name": "SLPI", "organism": "Pig", "refseq_name": "antileukoproteinase precursor", "refseq_ac": "NP_999035", "gene_names_uniprotkb": "SLPI; ALP", "gene_names_refseq": "ALP; SLPI", "protein_names_uniprotkb": "Antileukoproteinase; ALP; Secretory leukocyte protease inhibitor", "protein_names_refseq": "antileukoproteinase precursor; secretory leukocyte protease inhibitor", "tax_id": 9823, "disease": "", "pathway": " (ssc:396886)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "1547723;2293019", "class_list": "", "function": "Acid-stable proteinase inhibitor with strong affinities for trypsin, chymotrypsin, elastase, and cathepsin G. Modulates the inflammatory and immune responses after bacterial infection, and after infection by the intracellular parasite L.major. Down-regulates responses to bacterial lipopolysaccharide (LPS). Plays a role in regulating the activation of NF-kappa-B and inflammatory responses. Has antimicrobial activity against mycobacteria, but not against salmonella. Contributes to normal resistance against infection by M.tuberculosis. Required for normal resistance to infection by L.major. Required for normal wound healing, probably by preventing tissue damage by limiting protease activity (By similarity). Together with ELANE, required for normal differentiation and proliferation of bone marrow myeloid cells (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004867 serine-type endopeptidase inhibitor activity;GO:0004866 endopeptidase inhibitor activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0006955 immune response;GO:0019731 antibacterial humoral response;GO:0032496 response to lipopolysaccharide;GO:0045087 innate immune response", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "P22298-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P22952-1", "uniprot_id": "AMC2_PIG", "mass": 12343.0, "length": 117, "protein_name": "Alveolar macrophage chemotactic factor 2", "gene_name": "", "organism": "Pig", "refseq_name": "alveolar macrophage chemotactic factor 2 precursor", "refseq_ac": "NP_999041", "gene_names_uniprotkb": "", "gene_names_refseq": "AMCF-II; CXCL6", "protein_names_uniprotkb": "Alveolar macrophage chemotactic factor 2; AMCF-II; Alveolar macrophage chemotactic factor II", "protein_names_refseq": "alveolar macrophage chemotactic factor 2 precursor; alveolar macrophage chemotactic factor 2; alveolar macrophage chemotactic factor II; chemokine (C-X-C motif) ligand 6", "tax_id": 9823, "disease": "", "pathway": " (ssc:396900); (R-SSC-380108); (R-SSC-418594)", "pathway_count": 3, "publication_count": 2, "publication_id_list": "1420165;1850745", "class_list": "", "function": "Has chemotactic activity for porcine, and in a lesser extent, for human neutrophils., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008009 chemokine activity;GO:0045236 CXCR chemokine receptor binding", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0006954 inflammatory response;GO:0061844 antimicrobial humoral immune response mediated by antimicrobial peptide;GO:0071222 cellular response to lipopolysaccharide;GO:0042119 neutrophil activation;GO:0030593 neutrophil chemotaxis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "P22952-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P24020-1", "uniprot_id": "AQN3_PIG", "mass": 12885.0, "length": 116, "protein_name": "Carbohydrate-binding protein AQN-3", "gene_name": "", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "", "gene_names_refseq": "", "protein_names_uniprotkb": "Carbohydrate-binding protein AQN-3; Spermadhesin AQN-3; Zona pellucida-binding protein AQN-3", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 3, "publication_id_list": "1936247;8269963;8603690", "class_list": "", "function": "AQN proteins mediate the binding of boar spermatozoa to component(s) of the egg's zona pellucida by a carbohydrate-binding mechanism. AQN proteins are secretory components of the male accessory glands being coated to the sperm surface at the time of ejaculation. They possess as well heparin-, serine-protease-inhibitor-binding capability., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008201 heparin binding", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "GO:0007338 single fertilization", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "P24020-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P24540-1", "uniprot_id": "ACYP1_PIG", "mass": 11427.0, "length": 101, "protein_name": "Acylphosphatase-1", "gene_name": "ACYP1", "organism": "Pig", "refseq_name": "acylphosphatase-1 isoform 2", "refseq_ac": "NP_001177128", "gene_names_uniprotkb": "ACYP1; ACYPE", "gene_names_refseq": "ACYP1; ACYPE", "protein_names_uniprotkb": "Acylphosphatase-1; 3.6.1.7; Acylphosphatase, organ-common type isozyme; Acylphosphate phosphohydrolase 1", "protein_names_refseq": "Acylphosphatase, organ-common type isozyme; Acylphosphatase-1; Acylphosphate phosphohydrolase 1; acylphosphatase 1, erythrocyte (common) type; acylphosphatase-1 isoform 2", "tax_id": 9823, "disease": "", "pathway": " (ssc:100155997)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "1664426", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003998 acylphosphatase activity", "go_cellular_component": "", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "P24540-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P24853-1", "uniprot_id": "IBP2_PIG", "mass": 33937.0, "length": 316, "protein_name": "Insulin-like growth factor-binding protein 2", "gene_name": "IGFBP2", "organism": "Pig", "refseq_name": "insulin-like growth factor-binding protein 2 precursor", "refseq_ac": "NP_999168", "gene_names_uniprotkb": "IGFBP2", "gene_names_refseq": "IGFBP2; pIGFBP-2", "protein_names_uniprotkb": "Insulin-like growth factor-binding protein 2; IBP-2; IGF-binding protein 2; IGFBP-2; pIGFBP-2", "protein_names_refseq": "IBP-2; IGF-binding protein 2; IGFBP-2; insulin-like growth factor-binding protein 2 precursor", "tax_id": 9823, "disease": "", "pathway": " (ssc:397064); (R-SSC-381426)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "10601973;1722398;18427978", "class_list": "", "function": "May have both growth-inhibiting and growth-promoting effects, depending on tissue type; increases IGF-induced DNA synthesis in the uterine epithelium. IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors., [UniProtKB, PubMed]; Multifunctional protein that plays a critical role in regulating the availability of IGFs such as IGF1 and IGF2 to their receptors and thereby regulates IGF-mediated cellular processes including proliferation, differentiation, and apoptosis in a cell-type specific manner. Functions coordinately with receptor protein tyrosine phosphatase beta/PTPRB and the IGF1 receptor to regulate IGF1-mediated signaling by stimulating the phosphorylation of PTEN leading to its inactivation and AKT1 activation. Plays a positive role in cell migration via interaction with integrin alpha5/ITGA5 through an RGD motif. Additionally, interaction with ITGA5/ITGB1 enhances the adhesion of endothelial progenitor cells to endothelial cells. Upon mitochondrial damage, facilitates apoptosis with ITGA5 of podocytes, and then activates the phosphorylation of focal adhesion kinase (FAK)-mediated mitochondrial injury., [UniProtKB, UniProtKB]; Results suggest that IGFBP-2 is associated with production performance in pigs., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9XSC7", "ec_number_list": "", "go_molecular_function": "GO:0031994 insulin-like growth factor I binding;GO:0031995 insulin-like growth factor II binding;GO:0141069 receptor ligand inhibitor activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0005615 extracellular space", "go_biological_process": "GO:0032868 response to insulin;GO:0001649 osteoblast differentiation;GO:0042104 positive regulation of activated T cell proliferation;GO:0043567 regulation of insulin-like growth factor receptor signaling pathway;GO:0045927 positive regulation of growth", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "P24853-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P24964-1", "uniprot_id": "CYB_PIG", "mass": 42782.0, "length": 379, "protein_name": "Cytochrome b", "gene_name": "MT-CYB", "organism": "Pig", "refseq_name": "cytochrome b", "refseq_ac": "NP_008646", "gene_names_uniprotkb": "MT-CYB; COB; CYTB; MTCYB", "gene_names_refseq": "CYTB", "protein_names_uniprotkb": "Cytochrome b; Complex III subunit 3; Complex III subunit III; Cytochrome b-c1 complex subunit 3; Ubiquinol-cytochrome-c reductase complex cytochrome b subunit", "protein_names_refseq": "cytochrome b", "tax_id": 9823, "disease": "", "pathway": " (ssc:808513)", "pathway_count": 1, "publication_count": 9, "publication_id_list": "10433971;10747069;11428467;14510666;14557390;1901092;22690928;7486249;9732457", "class_list": "", "function": "Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "O78725;Q35918;Q36542;Q36550;Q36979;Q37077;Q94PU4;Q9T433", "ec_number_list": "", "go_molecular_function": "GO:0046872 metal ion binding;GO:0016491 oxidoreductase activity;GO:0008121 quinol-cytochrome-c reductase activity", "go_cellular_component": "GO:0005743 mitochondrial inner membrane;GO:0016020 membrane;GO:0045275 respiratory chain complex III", "go_biological_process": "GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "P24964-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P26429-1", "uniprot_id": "SC5A1_PIG", "mass": 73042.0, "length": 662, "protein_name": "Sodium/glucose cotransporter 1", "gene_name": "SLC5A1", "organism": "Pig", "refseq_name": "sodium/glucose cotransporter 1", "refseq_ac": "NP_001157493", "gene_names_uniprotkb": "SLC5A1; SGLT1", "gene_names_refseq": "SGLT1; SLC5A1", "protein_names_uniprotkb": "Sodium/glucose cotransporter 1; High affinity sodium-glucose cotransporter; Na(+)/glucose cotransporter 1; Solute carrier family 5 member 1", "protein_names_refseq": "Na(+)/glucose cotransporter 1; Na+/glucose cotransporter; high affinity sodium-glucose cotransporter; sodium/glucose cotransporter 1; solute carrier family 5 (sodium/glucose cotransporter), member 1", "tax_id": 9823, "disease": "", "pathway": " (ssc:397113)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "2247068;26924216;32543654", "class_list": "", "function": "Electrogenic Na(+)-coupled sugar symporter that actively transports D-glucose or D-galactose at the plasma membrane, with a Na(+) to sugar coupling ratio of 2:1. Transporter activity is driven by a transmembrane Na(+) electrochemical gradient set by the Na(+)/K(+) pump (By similarity). Has a primary role in the transport of dietary monosaccharides from enterocytes to blood. Responsible for the absorption of D-glucose or D-galactose across the apical brush-border membrane of enterocytes, whereas basolateral exit is provided by GLUT2. Additionally, functions as a D-glucose sensor in enteroendocrine cells, triggering the secretion of the incretins GCG and GIP that control food intake and energy homeostasis (By similarity). Together with SGLT2, functions in reabsorption of D-glucose from glomerular filtrate, playing a nonredundant role in the S3 segment of the proximal tubules (By similarity). Transports D-glucose into endometrial epithelial cells, controlling glycogen synthesis and nutritional support for the embryo as well as the decidual transformation of endometrium prior to conception (By similarity). Acts as a water channel enabling passive water transport in response to the osmotic gradient created upon sugar and Na(+) uptake. Has high water conductivity comparable to aquaporins and therefore is expected to play an important role in transepithelial water permeability, especially in the small intestine., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A0A140H1A0;A0A4X1V5B9;F1RLV1", "ec_number_list": "", "go_molecular_function": "GO:0005412 D-glucose:sodium symporter activity;GO:0005372 water transmembrane transporter activity;GO:0015371 galactose:sodium symporter activity;GO:0008324 monoatomic cation transmembrane transporter activity;GO:0015293 symporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016324 apical plasma membrane", "go_biological_process": "GO:0035623 renal D-glucose absorption;GO:0001951 intestinal D-glucose absorption;GO:0098708 D-glucose import across plasma membrane;GO:0006814 sodium ion transport", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "P26429-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P26445-1", "uniprot_id": "TNFB_PIG", "mass": 21960.0, "length": 204, "protein_name": "Lymphotoxin-alpha", "gene_name": "LTA", "organism": "Pig", "refseq_name": "lymphotoxin-alpha precursor", "refseq_ac": "NP_999618", "gene_names_uniprotkb": "LTA; TNFB; TNFSF1", "gene_names_refseq": "LTA; TNFB", "protein_names_uniprotkb": "Lymphotoxin-alpha; LT-alpha; TNF-beta; Tumor necrosis factor ligand superfamily member 1", "protein_names_refseq": "LT-alpha; TNF-beta; lymphotoxin alpha (TNF superfamily, member 1); lymphotoxin-alpha precursor; tumor necrosis factor ligand superfamily member 1; tumour necrosis factor beta", "tax_id": 9823, "disease": "", "pathway": " (ssc:407742); (R-SSC-5668541); (R-SSC-5669034); (R-SSC-5676594)", "pathway_count": 4, "publication_count": 2, "publication_id_list": "11169259;1874444", "class_list": "", "function": "Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM (By similarity). In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and is cytotoxic for a wide range of tumor cells in vitro and in vivo., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "A5D9N9", "ec_number_list": "", "go_molecular_function": "GO:0005125 cytokine activity;GO:0005164 tumor necrosis factor receptor binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005886 plasma membrane", "go_biological_process": "GO:0006955 immune response;GO:0007166 cell surface receptor signaling pathway;GO:0043123 positive regulation of canonical NF-kappaB signal transduction;GO:2001238 positive regulation of extrinsic apoptotic signaling pathway;GO:0006959 humoral immune response", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "P26445-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P26776-1", "uniprot_id": "AWN_PIG", "mass": 16730.0, "length": 153, "protein_name": "Carbohydrate-binding protein AWN", "gene_name": "", "organism": "Pig", "refseq_name": "carbohydrate-binding protein AWN precursor", "refseq_ac": "NP_998994", "gene_names_uniprotkb": "", "gene_names_refseq": "AWN", "protein_names_uniprotkb": "Carbohydrate-binding protein AWN; Sperm-associated protein AWN; Spermadhesin AWN; Zona pellucida-binding protein AWN", "protein_names_refseq": "carbohydrate-binding protein AWN precursor; carbohydrate-binding protein AWN; sperm-associated protein AWN; spermadhesin AWN; zona pellucida-binding protein AWN", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 3, "publication_id_list": "1540644;1555646;8603690", "class_list": "", "function": "AWN proteins mediate the binding of boar spermatozoa to component(s) of the egg's zona pellucida by a carbohydrate-binding mechanism. Awn proteins are secretory components of the male accessory glands being coated to the sperm surface at the time of ejaculation. They possess as well heparin-, serine-protease-inhibitor-binding capability., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q712L0", "ec_number_list": "", "go_molecular_function": "GO:0008201 heparin binding", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "GO:0007338 single fertilization", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "P26776-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P26889-1", "uniprot_id": "IL1B_PIG", "mass": 30404.0, "length": 267, "protein_name": "Interleukin-1 beta", "gene_name": "IL1B", "organism": "Pig", "refseq_name": "interleukin-1 beta", "refseq_ac": "NP_999220", "gene_names_uniprotkb": "IL1B", "gene_names_refseq": "IL1B1; IL1B", "protein_names_uniprotkb": "Interleukin-1 beta; IL-1 beta", "protein_names_refseq": "IL-1 beta; interleukin 1, beta 1; interleukin-1 beta; prointerleukin-1 beta", "tax_id": 9823, "disease": "", "pathway": " (ssc:397122)", "pathway_count": 1, "publication_count": 7, "publication_id_list": "29605728;30013955;30473357;31614911;31684202;35062226;8325511", "class_list": "", "function": "Data indicated that Porcine reproductive and respiratory syndrome virus infection could induce IL-1beta up-regulation, which was likely mediated by MyD88/ERK/AP-1 and NLRP3 inflammasome., [RefSeq, PubMed]; FMDV Leader Protein Interacts with the NACHT and LRR Domains of NLRP3 to Promote IL-1beta Production. Publication Status: Online-Only, [RefSeq, PubMed]; Porcine Circovirus Type 2 Induces Single Immunoglobulin Interleukin-1 Related Receptor (SIGIRR) Downregulation to Promote Interleukin-1beta Upregulation in Porcine Alveolar Macrophage. Publication Status: Online-Only, [RefSeq, PubMed]; Potent pro-inflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells. Plays a role in angiogenesis by inducing VEGF production synergistically with TNF and IL6. Involved in transduction of inflammation downstream of pyroptosis: its mature form is specifically released in the extracellular milieu by passing through the gasdermin-D (GSDMD) pore., [UniProtKB, UniProtKB]; These studies showed that classical swine fever virus-induced IL-1beta secretion was mediated by NLRP3 and that classical swine fever virus infection could sufficiently activate the assembly of the NLRP3 inflammasome in monocytes. Publication Status: Online-Only, [RefSeq, PubMed]; This study provides evidence that IL-1beta combined with IL-17A promoted chronic inflammatory arthritis by activating the catabolic processes accompanied with the suppression of cartilage anabolism. These suggest that further applications, which suppress inflammatory enhancers, especially IL-17A, should be considered as a target for arthritis research and therapy. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005178 integrin binding;GO:0005125 cytokine activity;GO:0005149 interleukin-1 receptor binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005829 cytosol;GO:0005764 lysosome", "go_biological_process": "GO:2000866 positive regulation of estradiol secretion;GO:0033092 positive regulation of immature T cell proliferation in thymus;GO:0001660 fever generation;GO:0006954 inflammatory response;GO:0006955 immune response", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P26889-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P26891-1", "uniprot_id": "IL2_PIG", "mass": 17401.0, "length": 154, "protein_name": "Interleukin-2", "gene_name": "IL2", "organism": "Pig", "refseq_name": "interleukin-2 precursor", "refseq_ac": "NP_999026", "gene_names_uniprotkb": "IL2", "gene_names_refseq": "IL-2; IL2; POIL2; TCGF", "protein_names_uniprotkb": "Interleukin-2; IL-2; T-cell growth factor; TCGF", "protein_names_refseq": "T-cell growth factor; interleukin-2 precursor", "tax_id": 9823, "disease": "", "pathway": " (ssc:396868); (R-SSC-5673001); (R-SSC-9020558); (R-SSC-912526)", "pathway_count": 4, "publication_count": 4, "publication_id_list": "15050130;16195934;2054386;21530576", "class_list": "", "function": "A parameter of early mRNA expression during intestinal ischemia reperfusion injury, [RefSeq, PubMed]; Cytokine produced by activated CD4-positive helper T-cells and to a lesser extend activated CD8-positive T-cells and natural killer (NK) cells that plays pivotal roles in the immune response and tolerance. Binds to a receptor complex composed of either the high-affinity trimeric IL-2R (IL2RA/CD25, IL2RB/CD122 and IL2RG/CD132) or the low-affinity dimeric IL-2R (IL2RB and IL2RG). Interaction with the receptor leads to oligomerization and conformation changes in the IL-2R subunits resulting in downstream signaling starting with phosphorylation of JAK1 and JAK3. In turn, JAK1 and JAK3 phosphorylate the receptor to form a docking site leading to the phosphorylation of several substrates including STAT5. This process leads to activation of several pathways including STAT, phosphoinositide-3-kinase/PI3K and mitogen-activated protein kinase/MAPK pathways. Functions as a T-cell growth factor and can increase NK-cell cytolytic activity as well. Promotes strong proliferation of activated B-cells and subsequently immunoglobulin production. Plays a pivotal role in regulating the adaptive immune system by controlling the survival and proliferation of regulatory T-cells, which are required for the maintenance of immune tolerance. Moreover, participates in the differentiation and homeostasis of effector T-cell subsets, including Th1, Th2, Th17 as well as memory CD8-positive T-cells., [UniProtKB, UniProtKB]; The isolation and characterization of interleukin 2 from Tibetan swine are reported., [RefSeq, PubMed]; We observed that besides TCR stimulation Tregs require IL-2 for activation., [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005125 cytokine activity;GO:0008083 growth factor activity;GO:0005134 interleukin-2 receptor binding", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0002366 leukocyte activation involved in immune response;GO:0038110 interleukin-2-mediated signaling pathway;GO:2000320 negative regulation of T-helper 17 cell differentiation;GO:0032740 positive regulation of interleukin-17 production;GO:0002250 adaptive immune response", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P26891-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P26893-1", "uniprot_id": "IL6_PIG", "mass": 23953.0, "length": 212, "protein_name": "Interleukin-6", "gene_name": "IL6", "organism": "Pig", "refseq_name": "interleukin-6 precursor", "refseq_ac": "NP_999564", "gene_names_uniprotkb": "IL6", "gene_names_refseq": "IL-6; IL6", "protein_names_uniprotkb": "Interleukin-6; IL-6", "protein_names_refseq": "interleukin 6 (interferon, beta 2); interleukin-6 precursor; interleukin-6 protein", "tax_id": 9823, "disease": "", "pathway": " (ssc:399500)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "1497880;1873476;27125399;27385686;28193578;30317108", "class_list": "", "function": "Acts as an essential factor in bone homeostasis and on vessels directly or indirectly by induction of VEGF, resulting in increased angiogenesis activity and vascular permeability. Induces, through 'trans-signaling' and synergistically with IL1B and TNF, the production of VEGF. Involved in metabolic controls, is discharged into the bloodstream after muscle contraction increasing lipolysis and improving insulin resistance (By similarity). 'Trans-signaling' in central nervous system also regulates energy and glucose homeostasis. Mediates, through GLP-1, crosstalk between insulin-sensitive tissues, intestinal L cells and pancreatic islets to adapt to changes in insulin demand (By similarity). Also acts as a myokine (By similarity). Plays a protective role during liver injury, being required for maintenance of tissue regeneration (By similarity). Also has a pivotal role in iron metabolism by regulating HAMP/hepcidin expression upon inflammation or bacterial infection (By similarity). Through activation of IL6ST-YAP-NOTCH pathway, induces inflammation-induced epithelial regeneration (By similarity)., [UniProtKB, UniProtKB, UniProtKB]; Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism. Binds to IL6R, then the complex associates to the signaling subunit IL6ST/gp130 to trigger the intracellular IL6-signaling pathway. The interaction with the membrane-bound IL6R and IL6ST stimulates 'classic signaling', whereas the binding of IL6 and soluble IL6R to IL6ST stimulates 'trans-signaling'. Alternatively, 'cluster signaling' occurs when membrane-bound IL6:IL6R complexes on transmitter cells activate IL6ST receptors on neighboring receiver cells., [UniProtKB, UniProtKB]; IL6 is a potent inducer of the acute phase response. Rapid production of IL6 contributes to host defense during infection and tissue injury, but excessive IL6 synthesis is involved in disease pathology. In the innate immune response, is synthesized by myeloid cells, such as macrophages and dendritic cells, upon recognition of pathogens through toll-like receptors (TLRs) at the site of infection or tissue injury (By similarity). In the adaptive immune response, is required for the differentiation of B cells into immunoglobulin-secreting cells. Plays a major role in the differentiation of CD4(+) T cell subsets. Essential factor for the development of T follicular helper (Tfh) cells that are required for the induction of germinal-center formation. Required to drive naive CD4(+) T cells to the Th17 lineage. Also required for proliferation of myeloma cells and the survival of plasmablast cells (By similarity)., [UniProtKB, UniProtKB, UniProtKB]; Induction of ischemic osteonecrosis results in IL-6 production in the articular cartilage through an HIF-1-dependent pathway. IL-6 produced by hypoxic articular chondrocytes stimulates inflammatory cytokine responses in synovial cells., [RefSeq, PubMed]; The role of IL-6 and its signaling pathway in enhancing colonic proliferation.Il-6 is a key regulator of chronic intestinal inflammation., [RefSeq, PubMed]; This study shows of IL-6 to the form of post-traumatic osteoarthritis induced by 'idealized' anterior cruciate ligament reconstruction in a porcine model, [RefSeq, PubMed]; We showed that IL-6 did not directly promote the proliferation of theca interna cells., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q95KN6", "ec_number_list": "", "go_molecular_function": "GO:0005125 cytokine activity;GO:0008083 growth factor activity;GO:0005138 interleukin-6 receptor binding", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:2000866 positive regulation of estradiol secretion;GO:0072574 hepatocyte proliferation;GO:0006954 inflammatory response;GO:0006953 acute-phase response;GO:0042593 glucose homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P26893-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P28220-1", "uniprot_id": "SRBS2_PIG", "mass": 18180.0, "length": 158, "protein_name": "Sorbin and SH3 domain-containing protein 2", "gene_name": "SORBS2", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "SORBS2", "gene_names_refseq": "", "protein_names_uniprotkb": "Sorbin and SH3 domain-containing protein 2; Arg-binding protein 2; ArgBP2", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 2, "publication_id_list": "11786189;1915377", "class_list": "", "function": "Adapter protein that plays a role in the assembling of signaling complexes, being a link between ABL kinases and actin cytoskeleton. Can form complex with ABL1 and CBL, thus promoting ubiquitination and degradation of ABL1 or with AKT1 and PAK1, thus mediating AKT1-mediated activation of PAK1 (By similarity). May play a role in the regulation of pancreatic cell adhesion, possibly by acting on WASF1 phosphorylation, enhancing phosphorylation by ABL1, as well as dephosphorylation by PTPN12. Increases water and sodium absorption in the intestine and gall-bladder., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q95ME6", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005925 focal adhesion;GO:0030027 lamellipodium;GO:0048471 perinuclear region of cytoplasm;GO:0016324 apical plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "P28220-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P29804-1", "uniprot_id": "ODPA_PIG", "mass": 43365.0, "length": 390, "protein_name": "Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial", "gene_name": "PDHA1", "organism": "Pig", "refseq_name": "pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial", "refseq_ac": "XP_003360292", "gene_names_uniprotkb": "PDHA1", "gene_names_refseq": "PDHA1", "protein_names_uniprotkb": "Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial; 1.2.4.1; PDHE1-A type I", "protein_names_refseq": "PDHE1-A type I; pyruvate dehydrogenase (lipoamide) alpha 1; pyruvate dehydrogenase E1 alpha 1 subunit; pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial; pyruvate dehydrogenase alpha 1", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 3, "publication_id_list": "227365;2395657;32543654", "class_list": "", "function": "The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)., [UniProtKB, UniProtKB]; Together with PDHB forms the heterotetrameric E1 subunit of the pyruvate dehydrogenase (PDH) complex (By similarity). The PDH complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links cytoplasmic glycolysis and the mitochondrial tricarboxylic acid (TCA) cycle (By similarity). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and dihydrolipoamide dehydrogenase (E3) (By similarity). The E1 subunit catalyzes both the thiamine pyrophosphate (TPP)-dependent decarboxylation of pyruvate and the reductive acetylation of a lipoyl group covalently linked to the lipoyl-bearing domains of E2 (PubMed:227365)., [UniProtKB, PubMed, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A5K1VBH1", "ec_number_list": "", "go_molecular_function": "GO:0046872 metal ion binding;GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity;GO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix;GO:0045254 pyruvate dehydrogenase complex", "go_biological_process": "GO:0006099 tricarboxylic acid cycle;GO:0006006 glucose metabolic process;GO:0006086 pyruvate decarboxylation to acetyl-CoA", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "P29804-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P31346-1", "uniprot_id": "ANGI_PIG", "mass": 16505.0, "length": 147, "protein_name": "Angiogenin", "gene_name": "ANG", "organism": "Pig", "refseq_name": "angiogenin precursor", "refseq_ac": "NP_001038038", "gene_names_uniprotkb": "ANG", "gene_names_refseq": "ANG1; ANG", "protein_names_uniprotkb": "Angiogenin; 3.1.27.-; RNase 5; Ribonuclease 5", "protein_names_refseq": "RNase 5; Ribonuclease 5; angiogenin precursor", "tax_id": 9823, "disease": "", "pathway": " (ssc:733639)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "19247805;31549540;8448182", "class_list": "", "function": "Anaemia was more common in younger piglets with RNASE1 GA genotype. ANG gene polymorphism was associated with the severity of iron deficiency in younger piglets. Varying levels of iron status and red blood cell indices in RNASE6 genotypes presumably resulted from the coupling of genes involved in iron metabolism and expressed in an age-dependent manner., [RefSeq, PubMed]; Association analyses revealed the significant associations (P < 0.05) between the porcine ANG g. 149G>T polymorphism and mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), mean platelet volume (MPV) and platelet-large cell ratio (P-LCR)., [RefSeq, PubMed]; Secreted ribonuclease that can either promote or restrict cell proliferation of target cells, depending on the context (By similarity). Endocytosed in target cells via its receptor PLXNB2 and translocates to the cytoplasm or nucleus (By similarity). Under stress conditions, localizes to the cytoplasm and promotes the assembly of stress granules (SGs): specifically cleaves a subset of tRNAs within anticodon loops to produce tRNA-derived stress-induced fragments (tiRNAs), resulting in translation repression and inhibition of cell proliferation (By similarity). tiRNas also prevent formation of apoptosome, thereby promoting cell survival (By similarity). Preferentially cleaves RNAs between a pyrimidine and an adenosine residue, suggesting that it cleaves the anticodon loop of tRNA(Ala) (32-UUAGCAU-38) after positions 33 and 36 (By similarity). Cleaves a subset of tRNAs, including tRNA(Ala), tRNA(Glu), tRNA(Gly), tRNA(Lys), tRNA(Val), tRNA(His), tRNA(Asp) and tRNA(Sec) (By similarity). Under growth conditions and in differentiated cells, translocates to the nucleus and stimulates ribosomal RNA (rRNA) transcription, including that containing the initiation site sequences of 45S rRNA, thereby promoting cell growth and proliferation (By similarity). Angiogenin induces vascularization of normal and malignant tissues via its ability to promote rRNA transcription (PubMed:8448182). Involved in hematopoietic stem and progenitor cell (HSPC) growth and survival by promoting rRNA transcription in growth conditions and inhibiting translation in response to stress, respectively (By similarity). Mediates the crosstalk between myeloid and intestinal epithelial cells to protect the intestinal epithelial barrier integrity: secreted by myeloid cells and promotes intestinal epithelial cells proliferation and survival (By similarity). Also mediates osteoclast-endothelial cell crosstalk in growing bone: produced by osteoclasts and protects the neighboring vascular cells against senescence by promoting rRNA transcription (By similarity)., [UniProtKB, UniProtKB, PubMed, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A287A0F3;Q1HDU1", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0016787 hydrolase activity;GO:0042803 protein homodimerization activity;GO:0004519 endonuclease activity;GO:0004540 RNA nuclease activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005634 nucleus;GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0030426 growth cone", "go_biological_process": "GO:0032055 negative regulation of translation in response to stress;GO:0001525 angiogenesis;GO:0019731 antibacterial humoral response;GO:0043066 negative regulation of apoptotic process;GO:0045087 innate immune response", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "P31346-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P31636-1", "uniprot_id": "SC5A4_PIG", "mass": 72745.0, "length": 660, "protein_name": "Solute carrier family 5 member 4", "gene_name": "SLC5A4", "organism": "Pig", "refseq_name": "solute carrier family 5 member 4", "refseq_ac": "NP_999347", "gene_names_uniprotkb": "SLC5A4; SAAT1; SGLT3", "gene_names_refseq": "PSGLT2; SAAT1; SGLT3; SLC5A4", "protein_names_uniprotkb": "Solute carrier family 5 member 4; Low affinity sodium-glucose cotransporter", "protein_names_refseq": "Na(+)/glucose cotransporter 3; low affinity sodium-glucose cotransporter; low-affinity Na-dependent glucose cotransporter; sodium/glucose cotransporter 3; solute carrier family 5 (low affinity glucose cotransporter), member 4; solute carrier family 5 member 4", "tax_id": 9823, "disease": "", "pathway": " (ssc:397376); (R-SSC-189200)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "13130073;8077195;8420925", "class_list": "", "function": "Low-affinity sodium/D-glucose symporter with a great selectivity for sugars (D-glucose >> D-galactose) (PubMed:13130073, PubMed:8077195). Na(+) and D-glucose transport are tightly coupled at neutral pH, but at acidic pH, ion transport is uncoupled from sugar transport (PubMed:13130073, PubMed:8077195)., [UniProtKB, PubMed, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005362 low-affinity D-glucose:sodium symporter activity;GO:0005412 D-glucose:sodium symporter activity;GO:0022857 transmembrane transporter activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0035623 renal D-glucose absorption;GO:1904659 D-glucose transmembrane transport;GO:0098708 D-glucose import across plasma membrane", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "P31636-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P32194-1", "uniprot_id": "PG1_PIG", "mass": 16677.0, "length": 149, "protein_name": "Protegrin-1", "gene_name": "NPG1", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "NPG1", "gene_names_refseq": "", "protein_names_uniprotkb": "Protegrin-1; Neutrophil peptide 1; PG-1", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (ssc:100144483)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "7628604;8013647;8335113;8375505;8647100;8807886", "class_list": "", "function": "Microbicidal activity. Active against E.coli, Listeria monocytogenes and C.albicans, in vitro., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0001530 lipopolysaccharide binding", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0045087 innate immune response;GO:0050829 defense response to Gram-negative bacterium;GO:0050830 defense response to Gram-positive bacterium;GO:0061844 antimicrobial humoral immune response mediated by antimicrobial peptide", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P32194-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P32196-1", "uniprot_id": "PG3_PIG", "mass": 16578.0, "length": 149, "protein_name": "Protegrin-3", "gene_name": "NPG3", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "NPG3", "gene_names_refseq": "", "protein_names_uniprotkb": "Protegrin-3; PG-3", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 5, "publication_id_list": "12377122;14604526;7628604;8013647;8335113", "class_list": "", "function": "Microbicidal activity. Active against E.coli, Listeria monocytogenes and C.albicans, in vitro., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0001530 lipopolysaccharide binding", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0045087 innate immune response;GO:0050829 defense response to Gram-negative bacterium;GO:0050830 defense response to Gram-positive bacterium;GO:0061844 antimicrobial humoral immune response mediated by antimicrobial peptide", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P32196-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P32306-1", "uniprot_id": "OXYR_PIG", "mass": 42524.0, "length": 386, "protein_name": "Oxytocin receptor", "gene_name": "OXTR", "organism": "Pig", "refseq_name": "oxytocin receptor", "refseq_ac": "NP_999192", "gene_names_uniprotkb": "OXTR", "gene_names_refseq": "OXTR", "protein_names_uniprotkb": "Oxytocin receptor; OT-R", "protein_names_refseq": "OT-R; oxytocin receptor", "tax_id": 9823, "disease": "", "pathway": " (ssc:397092)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "8393786", "class_list": "", "function": "G protein-coupled receptor for oxytocin (OXT), a neuropeptide hormone released by the posterior pituitary gland that plays a key role in social behavior and other biological processes, such as milk ejection. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors, such as phospholipase C. OXTR is mainly coupled to G(q) G proteins and mediates production of diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) second messengers that modulate the activity of phosphatidylinositol 3-kinase and promote the release of Ca(2+) ions from intracellular stores, respectively. In presence of high levels of oxytocin, also coupled to G(i) G proteins, mediating inhibition of adenylate cyclase activity. Central release of oxytocin plays essential roles in social behavior, such as maternal care, social cognition and affiliative behaviors, triggering signaling that modulates neural circuits by altering ion channel activity, changing intrinsic neuronal properties and modifying synaptic transmission (both excitatory and inhibitory). Peripheral release of oxytocin (secretion into the bloodstream) promotes various processes, such as parturition, lactation or osteoblast differentiation. OXTR-mediated signaling promotes milk ejection by triggering and strengthening contraction of the smooth muscle of mammary gland., [UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004990 oxytocin receptor activity;GO:0005000 vasopressin receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway;GO:0007565 female pregnancy;GO:0032870 cellular response to hormone stimulus;GO:0045907 positive regulation of vasoconstriction;GO:0060137 maternal process involved in parturition", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "P32306-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P32307-1", "uniprot_id": "V2R_PIG", "mass": 40537.0, "length": 370, "protein_name": "Vasopressin V2 receptor", "gene_name": "AVPR2", "organism": "Pig", "refseq_name": "vasopressin V2 receptor", "refseq_ac": "NP_999397", "gene_names_uniprotkb": "AVPR2", "gene_names_refseq": "AVPR2", "protein_names_uniprotkb": "Vasopressin V2 receptor; AVPR V2; Antidiuretic hormone receptor; Renal-type arginine vasopressin receptor; V2R", "protein_names_refseq": "AVPR V2; V-2 lysine vasopressin receptor; V2R; antidiuretic hormone receptor; arginine vasopressin receptor 2 (nephrogenic diabetes insipidus); renal-type arginine vasopressin receptor; vasopressin V2 receptor", "tax_id": 9823, "disease": "", "pathway": " (ssc:397462)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "18945824;27089501;8393786", "class_list": "", "function": "AQP1, AQP2, and AQP3, and V2R expression increased with gestation age in the fetal kidney, suggesting that this induction might contribute to the maturation of urinary concentrating capacity, [RefSeq, PubMed]; G protein-coupled receptor for arginine vasopressin, an antidiuretic that promotes renal water reabsorption (PubMed:8393786). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors, such as adenylate cyclase (cAMP) (By similarity). AVPR2 is coupled to G(s) G alpha proteins and mediates activation of adenylate cyclase activity (By similarity)., [UniProtKB, UniProtKB, PubMed]; Type 2 vasopressin receptor (V2R) is in primary cilia of renal epithelial cells. There is also a functional cAMP-signaling pathway, which targets ciliary channel function and may help control the sensory function of the primary cilium., [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 9, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005000 vasopressin receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway;GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0010628 positive regulation of gene expression;GO:0032870 cellular response to hormone stimulus;GO:0045907 positive regulation of vasoconstriction", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "P32307-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P34930-1", "uniprot_id": "HS71A_PIG", "mass": 70083.0, "length": 641, "protein_name": "Heat shock 70 kDa protein 1A", "gene_name": "HSPA1A", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "HSPA1A; HSPA1", "gene_names_refseq": "", "protein_names_uniprotkb": "Heat shock 70 kDa protein 1A; HSP70.1; Heat shock 70 kDa protein 1", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "1339404", "class_list": "", "function": "Molecular chaperone implicated in a wide variety of cellular processes, including protection of the proteome from stress, folding and transport of newly synthesized polypeptides, activation of proteolysis of misfolded proteins and the formation and dissociation of protein complexes. Plays a pivotal role in the protein quality control system, ensuring the correct folding of proteins, the re-folding of misfolded proteins and controlling the targeting of proteins for subsequent degradation. This is achieved through cycles of ATP binding, ATP hydrolysis and ADP release, mediated by co-chaperones. The co-chaperones have been shown to not only regulate different steps of the ATPase cycle, but they also have an individual specificity such that one co-chaperone may promote folding of a substrate while another may promote degradation. The affinity for polypeptides is regulated by its nucleotide bound state. In the ATP-bound form, it has a low affinity for substrate proteins. However, upon hydrolysis of the ATP to ADP, it undergoes a conformational change that increases its affinity for substrate proteins. It goes through repeated cycles of ATP hydrolysis and nucleotide exchange, which permits cycles of substrate binding and release. The co-chaperones are of three types: J-domain co-chaperones such as HSP40s (stimulate ATPase hydrolysis by HSP70), the nucleotide exchange factors (NEF) such as BAG1/2/3 (facilitate conversion of HSP70 from the ADP-bound to the ATP-bound state thereby promoting substrate release), and the TPR domain chaperones such as HOPX and STUB1. Maintains protein homeostasis during cellular stress through two opposing mechanisms: protein refolding and degradation. Its acetylation/deacetylation state determines whether it functions in protein refolding or protein degradation by controlling the competitive binding of co-chaperones HOPX and STUB1. During the early stress response, the acetylated form binds to HOPX which assists in chaperone-mediated protein refolding, thereafter, it is deacetylated and binds to ubiquitin ligase STUB1 that promotes ubiquitin-mediated protein degradation. Regulates centrosome integrity during mitosis, and is required for the maintenance of a functional mitotic centrosome that supports the assembly of a bipolar mitotic spindle. Enhances STUB1-mediated SMAD3 ubiquitination and degradation and facilitates STUB1-mediated inhibition of TGF-beta signaling. Essential for STUB1-mediated ubiquitination and degradation of FOXP3 in regulatory T-cells (Treg) during inflammation. Required as a co-chaperone for optimal STUB1/CHIP ubiquitination of NFATC3 (By similarity). Negatively regulates heat shock-induced HSF1 transcriptional activity during the attenuation and recovery phase period of the heat shock response., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0003714 transcription corepressor activity;GO:0016887 ATP hydrolysis activity;GO:0031072 heat shock protein binding;GO:0044183 protein folding chaperone", "go_cellular_component": "GO:0005576 extracellular region;GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005813 centrosome;GO:0005829 cytosol", "go_biological_process": "GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0007041 lysosomal transport;GO:0042026 protein refolding;GO:1901673 regulation of mitotic spindle assembly", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "P34930-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P34999-1", "uniprot_id": "GHRHR_PIG", "mass": 47200.0, "length": 423, "protein_name": "Growth hormone-releasing hormone receptor", "gene_name": "GHRHR", "organism": "Pig", "refseq_name": "growth hormone-releasing hormone receptor precursor", "refseq_ac": "NP_999200", "gene_names_uniprotkb": "GHRHR", "gene_names_refseq": "GHRHR", "protein_names_uniprotkb": "Growth hormone-releasing hormone receptor; GHRH receptor; GRF receptor; GRFR; Growth hormone-releasing factor receptor", "protein_names_refseq": "GHRH receptor; GRF receptor; GRFR; growth hormone-releasing factor receptor; growth hormone-releasing hormone receptor precursor", "tax_id": 9823, "disease": "", "pathway": " (ssc:397100)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "19212008;25404316;8413847", "class_list": "", "function": "Changes in the expression of genes encoding beta-LH and GnRH-R were also demonstrated across the estrous cycle in swine, [RefSeq, PubMed]; Data show that cardiac stem cells (CSCs) isolated from mouse, rat and pig myocardium express growth hormone-releasing hormone receptor (GHRH-R) and agonists of GHRH-R stimulate their proliferation and survival., [RefSeq, PubMed]; Receptor for GRF, coupled to G proteins which activate adenylyl cyclase. Stimulates somatotroph cell growth, growth hormone gene transcription and growth hormone secretion., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q28993", "ec_number_list": "", "go_molecular_function": "GO:0019838 growth factor binding;GO:0017046 peptide hormone binding;GO:0008528 G protein-coupled peptide receptor activity;GO:0016520 growth hormone-releasing hormone receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007166 cell surface receptor signaling pathway;GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0008284 positive regulation of cell population proliferation;GO:0032868 response to insulin;GO:0040018 positive regulation of multicellular organism growth", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "P34999-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P35496-1", "uniprot_id": "PSP2_PIG", "mass": 14816.0, "length": 137, "protein_name": "Major seminal plasma glycoprotein PSP-II", "gene_name": "", "organism": "Pig", "refseq_name": "major seminal plasma glycoprotein PSP-II precursor", "refseq_ac": "NP_999001", "gene_names_uniprotkb": "", "gene_names_refseq": "PSP-II", "protein_names_uniprotkb": "Major seminal plasma glycoprotein PSP-II", "protein_names_refseq": "major seminal plasma glycoprotein PSP-II precursor; major seminal plasma glycoprotein PSP-II; spermadhesin PSP-II", "tax_id": 9823, "disease": "", "pathway": " (ssc:396817)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "10504403;1586165;16809275;17651403;19948361;31280183;7781775;8397818;9111145;9334740", "class_list": "", "function": "Ability of two fertility-related genomic markers (porcine seminal protein (PSP)-I and PSP-II) in spermatozoa to predict boar litter size in addition to conventional semen parameters., [RefSeq, PubMed]; PSP-I/PSP-II heterodimer in seminal plasma has a predominant role in triggering the recruitment of uterine polymorphonuclear neutrophils and T cells after mating, initiating a cascade of transient and long-lasting immunological events., [RefSeq, PubMed]; Results indicate that the seminal vesicles are the main source of PSP-I and PSP-II spermadhesins, although epididymal segments, testis and the bulbourethral gland also participate in the expression of both proteins, [RefSeq, PubMed]; The protective effect of the PSP-I/PSP-II heterodimer in spermatozoa appears to be related to its adhesion to the acrosomal area, and the loss of this protective effect coincides with a stepwise redistribution of PSP-I/PSP-II during incubation, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 1, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 2, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 2, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 2, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 36, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 72, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "GO:0007338 single fertilization", "synthesized_glycan_count": 0, "hit_score": 8.5, "record_id": "P35496-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P35624-1", "uniprot_id": "TIMP1_PIG", "mass": 23099.0, "length": 207, "protein_name": "Metalloproteinase inhibitor 1", "gene_name": "TIMP1", "organism": "Pig", "refseq_name": "metalloproteinase inhibitor 1 precursor", "refseq_ac": "NP_999022", "gene_names_uniprotkb": "TIMP1", "gene_names_refseq": "TIMP-1; TIMP1", "protein_names_uniprotkb": "Metalloproteinase inhibitor 1; TIMP-1; Tissue inhibitor of metalloproteinases 1", "protein_names_refseq": "collagenase inhibitor; metalloproteinase inhibitor 1 precursor; metalloproteinase inhibitor 1; metalloproteinase tissue inhibitor 1; tissue inhibitor of metalloproteinases 1", "tax_id": 9823, "disease": "", "pathway": " (ssc:396862)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "1312961;18326810;19342253;23710440;27866058", "class_list": "", "function": "Hemodialysis graft placement leads to early increases in wall shear stress, VEGF-A, pro-MMP-9, MMP-2, VEGFR-1, VEGFR-2, and TIMP-1, which may contribute to the development of venous stenosis., [RefSeq, PubMed]; Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor. Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16. Does not act on MMP14. Also functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1. Plays a role in integrin signaling (By similarity)., [UniProtKB]; Results indicate that leukemia inhibitory factor (LIF) and Oncostatin M increase the expression of MMP-1, MMP-3, and TIMP-1 several fold, and that their expression is reduced to basal levels in the presence of the LIF antagonist MH35-BD., [RefSeq, PubMed]; Results provide evidence for the utility of MMP9 and TIMP1 as markers of age- and lactocrine-sensitive porcine female reproductive tract development., [RefSeq, PubMed]; We demonstrated the presence of high molecular weight (HMW) complexes (130, 170, and 220 kDa) containing MMP9, TIMP1, and NGAL (also MMP2 in 220 kDa complex) without proteolytic activity., [RefSeq, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "Q9TT83;Q9TTB9", "ec_number_list": "", "go_molecular_function": "GO:0046872 metal ion binding;GO:0005125 cytokine activity;GO:0008083 growth factor activity;GO:0008191 metalloendopeptidase inhibitor activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0031012 extracellular matrix", "go_biological_process": "GO:0051045 negative regulation of membrane protein ectodomain proteolysis;GO:0008284 positive regulation of cell population proliferation;GO:0043086 negative regulation of catalytic activity;GO:0034097 response to cytokine;GO:0009725 response to hormone", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P35624-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P36393-1", "uniprot_id": "SRY_PIG", "mass": 27019.0, "length": 236, "protein_name": "Sex-determining region Y protein", "gene_name": "SRY", "organism": "Pig", "refseq_name": "sex-determining region Y protein", "refseq_ac": "NP_999617", "gene_names_uniprotkb": "SRY; TDF", "gene_names_refseq": "SRY; TDF", "protein_names_uniprotkb": "Sex-determining region Y protein; Testis-determining factor", "protein_names_refseq": "sex-determining region Y protein; testis-determining factor", "tax_id": 9823, "disease": "", "pathway": " (ssc:407740); (R-SSC-3769402)", "pathway_count": 2, "publication_count": 7, "publication_id_list": "16411204;18851760;33443157;7665371;7818163;8162230;8793057", "class_list": "", "function": "Knockout of the HMG domain of the porcine SRY gene causes sex reversal in gene-edited pigs., [RefSeq, PubMed]; New insights into SRY regulation through identification of 5' conserved sequence are reported. Publication Status: Online-Only, [RefSeq, PubMed]; The 4.6 Kb of pig SRY 5' flanking sequences supported reporter transgene expression within the male genital ridge but not within the neural crest., [RefSeq, PubMed]; Transcriptional regulator that controls a genetic switch in male development. It is necessary and sufficient for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells. Involved in different aspects of gene regulation including promoter activation or repression. Binds to the DNA consensus sequence 5'-[AT]AACAA[AT]-3'. SRY HMG box recognizes DNA by partial intercalation in the minor groove and promotes DNA bending. Also involved in pre-mRNA splicing (By similarity). In male adult brain involved in the maintenance of motor functions of dopaminergic neurons (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005516 calmodulin binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0016607 nuclear speck", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0010628 positive regulation of gene expression;GO:0030154 cell differentiation;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0007548 sex differentiation", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P36393-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P42639-1", "uniprot_id": "TPM1_PIG", "mass": 32707.0, "length": 284, "protein_name": "Tropomyosin alpha-1 chain", "gene_name": "TPM1", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "TPM1", "gene_names_refseq": "", "protein_names_uniprotkb": "Tropomyosin alpha-1 chain; Alpha-tropomyosin; Tropomyosin-1", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (ssc:100037999)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "10651038;1404362;7943254", "class_list": "", "function": "Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 8, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A1XQV3;Q9TRA2", "ec_number_list": "", "go_molecular_function": "GO:0042802 identical protein binding;GO:0042803 protein homodimerization activity;GO:0046982 protein heterodimerization activity;GO:0051015 actin filament binding", "go_cellular_component": "GO:0005884 actin filament;GO:0015629 actin cytoskeleton", "go_biological_process": "GO:0007015 actin filament organization;GO:0060048 cardiac muscle contraction", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "P42639-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P43030-1", "uniprot_id": "CXCL7_PIG", "mass": 12615.0, "length": 119, "protein_name": "Platelet basic protein", "gene_name": "PPBP", "organism": "Pig", "refseq_name": "platelet basic protein precursor", "refseq_ac": "NP_999027", "gene_names_uniprotkb": "PPBP; CXCL7; SCYB7", "gene_names_refseq": "CTAPIII/NAP-2; PPBP", "protein_names_uniprotkb": "Platelet basic protein; C-X-C motif chemokine 7; PBP; Small-inducible cytokine B7", "protein_names_refseq": "C-X-C motif chemokine 7; PBP; platelet basic protein precursor; platelet basic protein; small-inducible cytokine B7", "tax_id": 9823, "disease": "", "pathway": " (ssc:396870); (R-SSC-114608); (R-SSC-380108); (R-SSC-418594); (R-SSC-6798695)", "pathway_count": 5, "publication_count": 1, "publication_id_list": "7513641", "class_list": "", "function": "Chemoattractant factor for neutrophils., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008083 growth factor activity;GO:0008009 chemokine activity;GO:0045236 CXCR chemokine receptor binding", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0006954 inflammatory response;GO:0061844 antimicrobial humoral immune response mediated by antimicrobial peptide;GO:0071222 cellular response to lipopolysaccharide;GO:0051781 positive regulation of cell division;GO:0042119 neutrophil activation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "P43030-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P43367-1", "uniprot_id": "CAN2_PIG", "mass": 37809.0, "length": 324, "protein_name": "Calpain-2 catalytic subunit", "gene_name": "CAPN2", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "CAPN2", "gene_names_refseq": "", "protein_names_uniprotkb": "Calpain-2 catalytic subunit; 3.4.22.53; CANP 2; Calcium-activated neutral proteinase 2; Calpain M-type; Calpain-2 large subunit; M-calpain; Millimolar-calpain", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 2, "publication_id_list": "8312396;9728040", "class_list": "", "function": "Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Proteolytically cleaves MYOC at 'Arg-226'. Proteolytically cleaves CPEB3 following neuronal stimulation which abolishes CPEB3 translational repressor activity, leading to translation of CPEB3 target mRNAs., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004198 calcium-dependent cysteine-type endopeptidase activity;GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0030425 dendrite", "go_biological_process": "GO:0006508 proteolysis;GO:0071230 cellular response to amino acid stimulus", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "P43367-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P48321-1", "uniprot_id": "DCE2_PIG", "mass": 65388.0, "length": 585, "protein_name": "Glutamate decarboxylase 2", "gene_name": "GAD2", "organism": "Pig", "refseq_name": "glutamate decarboxylase 2", "refseq_ac": "NP_999060", "gene_names_uniprotkb": "GAD2; GAD65", "gene_names_refseq": "GAD2; GAD65", "protein_names_uniprotkb": "Glutamate decarboxylase 2; 4.1.1.15; 65 kDa glutamic acid decarboxylase; GAD-65; Glutamate decarboxylase 65 kDa isoform", "protein_names_refseq": "65 kDa glutamic acid decarboxylase; GAD-65; glutamate decarboxylase 2; glutamic acid decarboxylase", "tax_id": 9823, "disease": "", "pathway": " (ssc:396929); (R-SSC-888568); (R-SSC-888590)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "7835711", "class_list": "", "function": "Catalyzes the production of GABA., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q506P9", "ec_number_list": "", "go_molecular_function": "GO:0030170 pyridoxal phosphate binding;GO:0004351 glutamate decarboxylase activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0031410 cytoplasmic vesicle;GO:0042734 presynaptic membrane", "go_biological_process": "GO:0006540 gamma-aminobutyrate shunt;GO:0009449 gamma-aminobutyric acid biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "P48321-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P49059-1", "uniprot_id": "FSHR_PIG", "mass": 78173.0, "length": 695, "protein_name": "Follicle-stimulating hormone receptor", "gene_name": "FSHR", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "FSHR", "gene_names_refseq": "", "protein_names_uniprotkb": "Follicle-stimulating hormone receptor; FSH-R; Follitropin receptor", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (ssc:397679)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "7590277", "class_list": "", "function": "G protein-coupled receptor for follitropin, the follicle-stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways., [UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "O77514", "ec_number_list": "", "go_molecular_function": "GO:0004963 follicle-stimulating hormone receptor activity;GO:0008528 G protein-coupled peptide receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane;GO:0043235 receptor complex", "go_biological_process": "GO:0007186 G protein-coupled receptor signaling pathway;GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0051897 positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction;GO:0070374 positive regulation of ERK1 and ERK2 cascade;GO:0008584 male gonad development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "P49059-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P49157-1", "uniprot_id": "EPO_PIG", "mass": 21304.0, "length": 194, "protein_name": "Erythropoietin", "gene_name": "EPO", "organism": "Pig", "refseq_name": "erythropoietin precursor", "refseq_ac": "NP_999299", "gene_names_uniprotkb": "EPO", "gene_names_refseq": "EPO", "protein_names_uniprotkb": "Erythropoietin", "protein_names_refseq": "erythropoietin precursor", "tax_id": 9823, "disease": "", "pathway": " (ssc:397249); (R-SSC-9027276); (R-SSC-9027284)", "pathway_count": 3, "publication_count": 4, "publication_id_list": "11311851;19767525;19908127;8364201", "class_list": "", "function": "EPO might play a role as a survival factor or as a mitogen in developing cartilage tissue., [RefSeq, PubMed]; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3., [UniProtKB, UniProtKB]; Pyruvate-fortified cardioplegia evokes myocardial erythropoietin signaling in swine undergoing cardiopulmonary bypass., [RefSeq, PubMed]", "predicted_glycosites": 4, "predicted_n_glycosites": 4, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "Q9MYM8", "ec_number_list": "", "go_molecular_function": "GO:0030295 protein kinase activator activity;GO:0005125 cytokine activity;GO:0005179 hormone activity;GO:0005128 erythropoietin receptor binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0009986 cell surface", "go_biological_process": "GO:0046579 positive regulation of Ras protein signal transduction;GO:0043249 erythrocyte maturation;GO:0000122 negative regulation of transcription by RNA polymerase II;GO:0008284 positive regulation of cell population proliferation;GO:0030218 erythrocyte differentiation", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P49157-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P49812-1", "uniprot_id": "MYOG_PIG", "mass": 25085.0, "length": 224, "protein_name": "Myogenin", "gene_name": "MYOG", "organism": "Pig", "refseq_name": "myogenin", "refseq_ac": "NP_001012406", "gene_names_uniprotkb": "MYOG", "gene_names_refseq": "MYOG", "protein_names_uniprotkb": "Myogenin", "protein_names_refseq": "myogenin factor; myogenin", "tax_id": 9823, "disease": "", "pathway": " (ssc:497618); (R-SSC-525793)", "pathway_count": 2, "publication_count": 5, "publication_id_list": "16682754;17112970;18462612;20640787;28799830", "class_list": "", "function": "Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation, cell cycle exit and muscle atrophy. Essential for the development of functional embryonic skeletal fiber muscle differentiation. However is dispensable for postnatal skeletal muscle growth; phosphorylation by CAMK2G inhibits its transcriptional activity in respons to muscle activity. Required for the recruitment of the FACT complex to muscle-specific promoter regions, thus promoting gene expression initiation. During terminal myoblast differentiation, plays a role as a strong activator of transcription at loci with an open chromatin structure previously initiated by MYOD1. Together with MYF5 and MYOD1, co-occupies muscle-specific gene promoter core regions during myogenesis. Also cooperates with myocyte-specific enhancer factor MEF2D and BRG1-dependent recruitment of SWI/SNF chromatin-remodeling enzymes to alter chromatin structure at myogenic late gene promoters. Facilitates cell cycle exit during terminal muscle differentiation through the up-regulation of miR-20a expression, which in turn represses genes involved in cell cycle progression. Binds to the E-box containing (E1) promoter region of the miR-20a gene. Also plays a role in preventing reversal of muscle cell differentiation. Contributes to the atrophy-related gene expression in adult denervated muscles. Induces fibroblasts to differentiate into myoblasts (By similarity)., [UniProtKB]; Mutation in exon 1 of the MYOG gene had no statistically significant association with carcass quality traits, [RefSeq, PubMed]; Relative MYOD1 expression was not different, but MYOG expression was higher in the (ligated-tube)crowded group embryos., [RefSeq, PubMed]; Significant differences were found in the birth weight and the backfat thickness among the different MyoG genotypes, [RefSeq, PubMed]; Studied the effects of microRNA-27a on myogenin expression and the Akt/FoxO1 signal pathway during porcine myoblast differentiation. Overexpression of miR-27a suppressed myogenin expression during porcine myoblast differentiation, whereas inhibition of miR-27a promoted the mRNA and protein expression levels of myogenin; overexpression of miR-27a decreased the level of P-Akt/Akt and increased the protein level of FoxO1., [RefSeq, PubMed]; The MyoG gene is very conservative and there are very few mutation sites between different breeds, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q5EC23;Q5EE03", "ec_number_list": "", "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0046983 protein dimerization activity;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0070888 E-box binding", "go_cellular_component": "GO:0005634 nucleus;GO:0032993 protein-DNA complex", "go_biological_process": "GO:0010831 positive regulation of myotube differentiation;GO:0014891 striated muscle atrophy;GO:0006351 DNA-templated transcription;GO:0008285 negative regulation of cell population proliferation;GO:0045944 positive regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P49812-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P49873-1", "uniprot_id": "CCL8_PIG", "mass": 10903.0, "length": 99, "protein_name": "C-C motif chemokine 8", "gene_name": "CCL8", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "CCL8; MCP2; SCYA8", "gene_names_refseq": "", "protein_names_uniprotkb": "C-C motif chemokine 8; MCP-2; Monocyte chemoattractant protein 2; Monocyte chemotactic protein 2; Small-inducible cytokine A8", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "7999015", "class_list": "", "function": "Chemotactic factor that attracts monocytes. This protein can bind heparin., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008201 heparin binding;GO:0008009 chemokine activity;GO:0048020 CCR chemokine receptor binding", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0006954 inflammatory response;GO:0030335 positive regulation of cell migration;GO:0061844 antimicrobial humoral immune response mediated by antimicrobial peptide;GO:0070098 chemokine-mediated signaling pathway;GO:0048245 eosinophil chemotaxis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "P49873-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P50129-1", "uniprot_id": "5HT2A_PIG", "mass": 52676.0, "length": 470, "protein_name": "5-hydroxytryptamine receptor 2A", "gene_name": "HTR2A", "organism": "Pig", "refseq_name": "5-hydroxytryptamine receptor 2A", "refseq_ac": "NP_999382", "gene_names_uniprotkb": "HTR2A", "gene_names_refseq": "5-HT2A; HTR2A", "protein_names_uniprotkb": "5-hydroxytryptamine receptor 2A; 5-HT-2A; 5-HT-2; 5-HT2A; Serotonin receptor 2A", "protein_names_refseq": "5-HT-2A; 5-HT-2; 5-HT2A receptor; 5-hydroxytryptamine receptor 2A; serotonin receptor 2A", "tax_id": 9823, "disease": "", "pathway": " (ssc:397432)", "pathway_count": 1, "publication_count": 6, "publication_id_list": "18653286;18952076;21865058;29104045;7656980;7794950", "class_list": "", "function": "5-HT2A receptor subtype is the predominant receptor mediating 5-HT responses in ureteral tissues, [RefSeq, PubMed]; Early weaning results in less active behaviour, accompanied by lower 5-HT1A and higher 5-HT2A receptor mRNA expression in specific brain regions., [RefSeq, PubMed]; Excitatory 5-HT(2A) and inhibitory 5-HT(7) are present in the uterus of non-pregnant pigs. Endogenous 5-HT containing cells are mainly present in uterine glands of the pig, [RefSeq, PubMed]; G protein-coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances, including mescaline, psilocybin, 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) and lysergic acid diethylamide (LSD). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors. HTR2A is coupled to G(q)/G(11) G alpha proteins and activates phospholipase C-beta, releasing diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) second messengers that modulate the activity of phosphatidylinositol 3-kinase and promote the release of Ca(2+) ions from intracellular stores, respectively. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Affects neural activity, perception, cognition and mood (By similarity). Plays a role in the regulation of behavior, including responses to anxiogenic situations and psychoactive substances. Plays a role in intestinal smooth muscle contraction, and may play a role in arterial vasoconstriction (By similarity)., [UniProtKB, UniProtKB, UniProtKB]; The 5-HT(2A) receptor subtype is sensitive to elevated stretch., [RefSeq, PubMed]", "predicted_glycosites": 6, "predicted_n_glycosites": 6, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 6, "binding_glycan_count": 0, "secondary_ac_list": "Q29004", "ec_number_list": "", "go_molecular_function": "GO:0004993 G protein-coupled serotonin receptor activity;GO:0030594 neurotransmitter receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0030424 axon;GO:0030425 dendrite;GO:0031410 cytoplasmic vesicle;GO:0005901 caveola", "go_biological_process": "GO:0007187 G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007268 chemical synaptic transmission;GO:0007210 serotonin receptor signaling pathway;GO:0051209 release of sequestered calcium ion into cytosol;GO:0007208 phospholipase C-activating serotonin receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.7, "record_id": "P50129-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P50130-1", "uniprot_id": "DRD1_PIG", "mass": 49257.0, "length": 446, "protein_name": "D(1A) dopamine receptor", "gene_name": "DRD1", "organism": "Pig", "refseq_name": "D(1A) dopamine receptor", "refseq_ac": "NP_001116580", "gene_names_uniprotkb": "DRD1", "gene_names_refseq": "DRD1", "protein_names_uniprotkb": "D(1A) dopamine receptor; Dopamine D1 receptor", "protein_names_refseq": "D(1A) dopamine receptor; dopamine D1 receptor", "tax_id": 9823, "disease": "", "pathway": " (ssc:100144487)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "16217657;7900842", "class_list": "", "function": "Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase. Forms heterotetramers with DRD3 to potentiate beta-arrestin recruitment and mediate locomotor activity., [UniProtKB, UniProtKB]; The results suggest that endocytosis of beta(1)-adrenoceptor in renal proximal tubular cells is an important step in signal generation, while endocytosis of proximal tubular D1 receptor is not., [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs", "go_cellular_component": "GO:0005886 plasma membrane;GO:0043197 dendritic spine;GO:0005789 endoplasmic reticulum membrane;GO:0060170 ciliary membrane", "go_biological_process": "GO:0043410 positive regulation of MAPK cascade;GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway;GO:0042311 vasodilation;GO:0007212 G protein-coupled dopamine receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "P50130-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P50390-1", "uniprot_id": "TTHY_PIG", "mass": 16081.0, "length": 150, "protein_name": "Transthyretin", "gene_name": "TTR", "organism": "Pig", "refseq_name": "transthyretin precursor", "refseq_ac": "NP_999377", "gene_names_uniprotkb": "TTR", "gene_names_refseq": "TTR", "protein_names_uniprotkb": "Transthyretin; Prealbumin", "protein_names_refseq": "prealbumin; transthyretin precursor", "tax_id": 9823, "disease": "", "pathway": " (ssc:397419); (R-SSC-2453902); (R-SSC-6798695); (R-SSC-975634)", "pathway_count": 4, "publication_count": 4, "publication_id_list": "17629575;21147258;7601162;8930078", "class_list": "", "function": "The rank order potency of the chemicals tested for the displacement of [125I]TIP from TTR was TIP > ioxynil > pentachlorophenol, T4, and retinoic acid > tetrabromobisphenol A, diethylstilbestrol, and T3., [RefSeq, PubMed]; This study suggested closer links between the release of haptoglobin, Pig-MAP and monocytes compared to the release of AGP, SAA and transthyretin., [RefSeq, PubMed]; Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q2IA93", "ec_number_list": "", "go_molecular_function": "GO:0070324 thyroid hormone binding;GO:0005179 hormone activity;GO:0036094 small molecule binding", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0006144 purine nucleobase metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P50390-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P50667-1", "uniprot_id": "COX2_PIG", "mass": 26185.0, "length": 228, "protein_name": "Cytochrome c oxidase subunit 2", "gene_name": "MT-CO2", "organism": "Pig", "refseq_name": "cytochrome c oxidase subunit II", "refseq_ac": "NP_008637", "gene_names_uniprotkb": "MT-CO2; COII; COX2; COXII; MTCO2", "gene_names_refseq": "COX2", "protein_names_uniprotkb": "Cytochrome c oxidase subunit 2; 7.1.1.9; Cytochrome c oxidase polypeptide II", "protein_names_refseq": "cytochrome c oxidase subunit II", "tax_id": 9823, "disease": "", "pathway": " (ssc:808504)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "10433971;7723053;9732457", "class_list": "", "function": "Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9TDR3", "ec_number_list": "", "go_molecular_function": "GO:0016491 oxidoreductase activity;GO:0005507 copper ion binding;GO:0004129 cytochrome-c oxidase activity", "go_cellular_component": "GO:0005743 mitochondrial inner membrane;GO:0031966 mitochondrial membrane;GO:0045277 respiratory chain complex IV", "go_biological_process": "GO:0042773 ATP synthesis coupled electron transport;GO:0017004 cytochrome complex assembly", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "P50667-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P50828-1", "uniprot_id": "HEMO_PIG", "mass": 51306.0, "length": 459, "protein_name": "Hemopexin", "gene_name": "HPX", "organism": "Pig", "refseq_name": "hemopexin precursor", "refseq_ac": "NP_999118", "gene_names_uniprotkb": "HPX", "gene_names_refseq": "HPX", "protein_names_uniprotkb": "Hemopexin; 3.2.1.35; Hyaluronidase", "protein_names_refseq": "hemopexin precursor; hyaluronidase", "tax_id": 9823, "disease": "", "pathway": " (ssc:396998)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "7798203", "class_list": "", "function": "Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation., [UniProtKB]", "predicted_glycosites": 4, "predicted_n_glycosites": 4, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0046872 metal ion binding;GO:0015232 heme transmembrane transporter activity;GO:0004415 hyalurononglucosaminidase activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0006879 intracellular iron ion homeostasis;GO:0042168 heme metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "P50828-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P51524-1", "uniprot_id": "PF11_PIG", "mass": 23956.0, "length": 212, "protein_name": "Prophenin and tritrpticin precursor", "gene_name": "", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "", "gene_names_refseq": "", "protein_names_uniprotkb": "Prophenin and tritrpticin precursor; C6", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 3, "publication_id_list": "16997878;7576250;7698355", "class_list": "", "function": "Cathelicidin-like peptide with antimicrobial and hemolytic activities., [UniProtKB, PubMed]; Exerts antimicrobial activity. It is more effective against Gram-negative bacteria than Gram-positive bacteria., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0001530 lipopolysaccharide binding", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0045087 innate immune response;GO:0050829 defense response to Gram-negative bacterium;GO:0050830 defense response to Gram-positive bacterium;GO:0061844 antimicrobial humoral immune response mediated by antimicrobial peptide", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "P51524-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P51525-1", "uniprot_id": "PF12_PIG", "mass": 25855.0, "length": 228, "protein_name": "Prophenin-2", "gene_name": "", "organism": "Pig", "refseq_name": "protegrin-4 precursor", "refseq_ac": "NP_999028", "gene_names_uniprotkb": "", "gene_names_refseq": "NPG4; PMAP37", "protein_names_uniprotkb": "Prophenin-2; C12; PF-2; PR-2; Prophenin-1-like", "protein_names_refseq": "C12; C6; PF-1; PF-2; PG-4; PR-2; Prophenin and tritrpticin; antibacterial peptide PMAP-37; homologue of proline/arginine rich antibacterial peptides; myeloid antibacterial peptide 37; prophenin-1; prophenin-2; protegrin-4 precursor", "tax_id": 9823, "disease": "", "pathway": " (ssc:396871)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "7498526;8262247", "class_list": "", "function": "Exerts antimicrobial activity. It is more effective against Gram-negative bacteria than Gram-positive bacteria., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0001530 lipopolysaccharide binding", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0045087 innate immune response;GO:0050829 defense response to Gram-negative bacterium;GO:0050830 defense response to Gram-positive bacterium;GO:0061844 antimicrobial humoral immune response mediated by antimicrobial peptide", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "P51525-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P51779-1", "uniprot_id": "CFAD_PIG", "mass": 27764.0, "length": 259, "protein_name": "Complement factor D", "gene_name": "CFD", "organism": "Pig", "refseq_name": "complement factor D precursor", "refseq_ac": "NP_001233173", "gene_names_uniprotkb": "CFD; DF", "gene_names_refseq": "CFD; DF", "protein_names_uniprotkb": "Complement factor D; 3.4.21.46; Adipsin; C3 convertase activator; Properdin factor D", "protein_names_refseq": "C3 convertase activator; adipsin; complement factor D precursor; complement factor D preproprotein; properdin factor D", "tax_id": 9823, "disease": "", "pathway": " (ssc:396877); (R-SSC-114608); (R-SSC-173736); (R-SSC-6798695)", "pathway_count": 4, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Serine protease that initiates the alternative pathway of the complement system, a cascade of proteins that leads to phagocytosis and breakdown of pathogens and signaling that strengthens the adaptive immune system. In contrast to other complement pathways (classical, lectin and GZMK) that are directly activated by pathogens or antigen-antibody complexes, the alternative complement pathway is initiated by the spontaneous hydrolysis of complement C3. The alternative complement pathway acts as an amplification loop that enhances complement activation by mediating the formation of C3 and C5 convertases. Activated CFD cleaves factor B (CFB) when the latter is complexed with complement C3b, activating the C3 convertase of the alternative pathway., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004252 serine-type endopeptidase activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0051604 protein maturation;GO:0031638 zymogen activation;GO:0006957 complement activation, alternative pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "P51779-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P51781-1", "uniprot_id": "GSTA1_PIG", "mass": 25281.0, "length": 222, "protein_name": "Glutathione S-transferase alpha M14", "gene_name": "", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "", "gene_names_refseq": "", "protein_names_uniprotkb": "Glutathione S-transferase alpha M14; 2.5.1.18; GST class-alpha", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (ssc:397682)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Glutathione S-transferase that catalyzes the nucleophilic attack of the sulfur atom of glutathione on the electrophilic groups of a wide range of exogenous and endogenous compounds. Involved in the formation of glutathione conjugates of both prostaglandin A2 (PGA2) and prostaglandin J2 (PGJ2). It also catalyzes the isomerization of D5-androstene-3,17-dione (AD) into D4-androstene-3,17-dione and may therefore play an important role in hormone biosynthesis. Through its glutathione-dependent peroxidase activity toward the fatty acid hydroperoxide (13S)-hydroperoxy-(9Z,11E)-octadecadienoate/13-HPODE it is also involved in the metabolism of oxidized linoleic acid., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004364 glutathione transferase activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0006805 xenobiotic metabolic process;GO:0006749 glutathione metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "P51781-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P52552-1", "uniprot_id": "PRDX2_PIG", "mass": 14168.0, "length": 127, "protein_name": "Peroxiredoxin-2", "gene_name": "PRDX2", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "PRDX2; TDPX1", "gene_names_refseq": "", "protein_names_uniprotkb": "Peroxiredoxin-2; 1.11.1.24; TSA; Thiol-specific antioxidant protein; Thioredoxin peroxidase 1; Thioredoxin-dependent peroxide reductase 1; Thioredoxin-dependent peroxiredoxin 2", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "8672129", "class_list": "", "function": "Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008379 thioredoxin peroxidase activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0006979 response to oxidative stress;GO:0045454 cell redox homeostasis;GO:0019430 removal of superoxide radicals;GO:0042744 hydrogen peroxide catabolic process;GO:0045321 leukocyte activation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "P52552-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P52650-1", "uniprot_id": "CY24A_PIG", "mass": 20745.0, "length": 192, "protein_name": "Cytochrome b-245 light chain", "gene_name": "CYBA", "organism": "Pig", "refseq_name": "cytochrome b-245 light chain", "refseq_ac": "NP_999432", "gene_names_uniprotkb": "CYBA", "gene_names_refseq": "CYBA; P22-PHOX; p22phox", "protein_names_uniprotkb": "Cytochrome b-245 light chain; Cytochrome b(558) alpha chain; Cytochrome b558 subunit alpha; Neutrophil cytochrome b 22 kDa polypeptide; Superoxide-generating NADPH oxidase light chain subunit; p22 phagocyte B-cytochrome; p22-phox; p22phox", "protein_names_refseq": "NADPH oxidase light chain subunit; cytochrome b(558) alpha chain; cytochrome b-245 light chain; cytochrome b-245, alpha polypeptide; cytochrome b558 subunit alpha; neutrophil cytochrome b 22 kDa polypeptide; p22 phagocyte B-cytochrome; superoxide-generating NADPH oxidase light chain subunit", "tax_id": 9823, "disease": "", "pathway": " (ssc:397507)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "15718491;18757525;19562688;7958970", "class_list": "", "function": "CRP inhibits endothelium-dependent NO-mediated dilation in coronary arterioles by producing superoxide from NAD(P)H oxidase via p38 kinase activation, [RefSeq, PubMed]; Reactive oxygen species generated by NADPH oxidase contribute to the aberrant pulmonary arterial responses in piglets exposed to 3 days of hypoxia., [RefSeq, PubMed]; Subunit of NADPH oxidase complexes that is required for the NADPH oxidase activity that generates, in various cell types, superoxide from molecular oxygen utilizing NADPH as an electron donor. Subunit of the phagocyte NADPH oxidase complex that mediates the transfer of electrons from cytosolic NADPH to O2 to produce the superoxide anion (O2(-)). In the activated complex, electrons are first transferred from NADPH to flavin adenine dinucleotide (FAD) and subsequently transferred via two heme molecules to molecular oxygen, producing superoxide through an outer-sphere reaction. Activation of the NADPH oxidase complex is initiated by the assembly of cytosolic subunits of the NADPH oxidase complex with the core NADPH oxidase complex to form a complex at the plasma membrane or phagosomal membrane. This activation process is initiated by phosphorylation dependent binding of the cytosolic NCF1/p47-phox subunit to the C-terminus of CYBA/p22-phox. Aassociates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide., [UniProtKB, UniProtKB]; Upregulation of PPAR-gamma and NADPH oxidases are involved in restenosis., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0046872 metal ion binding;GO:0016491 oxidoreductase activity;GO:0020037 heme binding", "go_cellular_component": "GO:0043020 NADPH oxidase complex;GO:0005886 plasma membrane", "go_biological_process": "GO:0045087 innate immune response;GO:0042554 superoxide anion generation", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P52650-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P56729-1", "uniprot_id": "SUIS_PIG", "mass": 210395.0, "length": 1827, "protein_name": "Sucrase-isomaltase, intestinal", "gene_name": "SI", "organism": "Pig", "refseq_name": "sucrase-isomaltase, intestinal", "refseq_ac": "XP_020925407", "gene_names_uniprotkb": "SI", "gene_names_refseq": "SI", "protein_names_uniprotkb": "Sucrase-isomaltase, intestinal", "protein_names_refseq": "sucrase-isomaltase, intestinal", "tax_id": 9823, "disease": "", "pathway": " (ssc:100623884)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "3121301;32543654;7152027", "class_list": "", "function": "Bifunctional enzyme with both sucrase and isomaltase activities involved in breakdown of dietary starch oligosaccharides in small intestine. The isomaltase domain hydrolazes alpha-1,6-glycosidic linkages in isomaltose. The sucrase domain cleaves the alpha-1,2-glycosidic linkages in sucrose to form glucose and fructose, and contributes to the cleavage of the alpha-1,4-glycosidic linkage in maltose to form two glucose monosaccharides., [UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "I3LI68", "ec_number_list": "", "go_molecular_function": "GO:0004574 oligo-1,6-glucosidase activity;GO:0004575 sucrose alpha-glucosidase activity", "go_cellular_component": "GO:0016324 apical plasma membrane", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "P56729-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P58392-1", "uniprot_id": "KCNN3_PIG", "mass": 80372.0, "length": 724, "protein_name": "Small conductance calcium-activated potassium channel protein 3", "gene_name": "KCNN3", "organism": "Pig", "refseq_name": "small conductance calcium-activated potassium channel protein 3", "refseq_ac": "NP_999150", "gene_names_uniprotkb": "KCNN3", "gene_names_refseq": "KCNN3; KCa2.3", "protein_names_uniprotkb": "Small conductance calcium-activated potassium channel protein 3; KCa2.3; SK3; SKCa 3; SKCa3", "protein_names_refseq": "SKCa 3; SKCa3; calcium activated potassium channel SK3; potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3; small conductance calcium-activated potassium channel protein 3", "tax_id": 9823, "disease": "", "pathway": " (ssc:397045); (R-SSC-1296052)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "11877319;18048454", "class_list": "", "function": "SK channels (KCNN1 and KCNN3) provide a mechanism for sensing changes in intracellular Ca(2+) near the apical membrane, evoking hyperpolarization necessary for increasing the driving force for anion efflux following P2Y receptor activation [KCNN1]., [RefSeq, PubMed]; Small conductance calcium-activated potassium channel that mediates the voltage-independent transmembrane transfer of potassium across the cell membrane through a constitutive interaction with calmodulin which binds the intracellular calcium allowing its opening (PubMed:11877319). The current is characterized by a voltage-independent activation, an intracellular calcium concentration increase-dependent activation and a single-channel conductance of 10 picosiemens (PubMed:11877319). Also presents an inwardly rectifying current, thus reducing its already small outward conductance of potassium ions, which is particularly the case when the membrane potential displays positive values, above + 20 mV (By similarity). Activation is followed by membrane hyperpolarization. Thought to regulate neuronal excitability by contributing to the slow component of synaptic afterhyperpolarization (By similarity)., [UniProtKB, UniProtKB, PubMed, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005516 calmodulin binding;GO:0016286 small conductance calcium-activated potassium channel activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0043025 neuronal cell body;GO:0043005 neuron projection;GO:0030018 Z disc", "go_biological_process": "GO:0071805 potassium ion transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "P58392-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P58780-1", "uniprot_id": "ADA2_PIG", "mass": 58190.0, "length": 510, "protein_name": "Adenosine deaminase 2", "gene_name": "ADA2", "organism": "Pig", "refseq_name": "adenosine deaminase 2 precursor", "refseq_ac": "NP_999181", "gene_names_uniprotkb": "ADA2; CECR1", "gene_names_refseq": "ADA2; CECR1", "protein_names_uniprotkb": "Adenosine deaminase 2; 3.5.4.4; Cat eye syndrome critical region protein 1", "protein_names_refseq": "adenosine deaminase 2 precursor; adenosine deaminase CECR1; cat eye syndrome chromosome region, candidate 1; cat eye syndrome critical region protein 1", "tax_id": 9823, "disease": "", "pathway": " (ssc:397079)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "11738815;23685153", "class_list": "", "function": "Adenosine deaminase that may contribute to the degradation of extracellular adenosine, a signaling molecule that controls a variety of cellular responses. Requires elevated adenosine levels for optimal enzyme activity. Binds to cell surfaces via proteoglycans and may play a role in the regulation of cell proliferation and differentiation, independently of its enzyme activity (By similarity)., [UniProtKB]; Increased ADA2 expression and activity are identified in human and porcine retinas with diabetes., [RefSeq, PubMed]", "predicted_glycosites": 4, "predicted_n_glycosites": 3, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "Q8WND6", "ec_number_list": "", "go_molecular_function": "GO:0004000 adenosine deaminase activity;GO:0008201 heparin binding;GO:0008270 zinc ion binding;GO:0031685 adenosine receptor binding;GO:0043394 proteoglycan binding", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0006154 adenosine catabolic process;GO:0046103 inosine biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "P58780-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P59083-1", "uniprot_id": "PHP14_PIG", "mass": 13932.0, "length": 126, "protein_name": "14 kDa phosphohistidine phosphatase", "gene_name": "PHPT1", "organism": "Pig", "refseq_name": "14 kDa phosphohistidine phosphatase isoform 1", "refseq_ac": "NP_001399201", "gene_names_uniprotkb": "PHPT1; PHP14", "gene_names_refseq": "PHP14; PHPT1; PHP", "protein_names_uniprotkb": "14 kDa phosphohistidine phosphatase; 3.9.1.3; PHPT1; PHP; Phosphohistidine phosphatase 1; Protein histidine phosphatase", "protein_names_refseq": "14 kDa phosphohistidine phosphatase isoform 1; 14 kDa phosphohistidine phosphatase; Protein histidine phosphatase", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "12383260", "class_list": "", "function": "Exhibits phosphohistidine phosphatase activity., [UniProtKB, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "F1RWN4", "ec_number_list": "", "go_molecular_function": "GO:0101006 protein histidine phosphatase activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:2000147 positive regulation of cell motility", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "P59083-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P60662-1", "uniprot_id": "MYL6_PIG", "mass": 16930.0, "length": 151, "protein_name": "Myosin light polypeptide 6", "gene_name": "MYL6", "organism": "Pig", "refseq_name": "myosin light polypeptide 6", "refseq_ac": "NP_001157469", "gene_names_uniprotkb": "MYL6", "gene_names_refseq": "MYL6", "protein_names_uniprotkb": "Myosin light polypeptide 6; 17 kDa myosin light chain; LC17; MLC-3; Myosin light chain 3; Myosin light chain A3; Myosin light chain alkali 3; Smooth muscle and nonmuscle myosin light chain alkali 6", "protein_names_refseq": "17 kDa myosin light chain; LC17; MLC-3; myosin light chain 3; myosin light chain A3; myosin light chain alkali 3; myosin light polypeptide 6; myosin, light chain 6, alkali, smooth muscle and non-muscle; non-muscle myosin light chain; smooth muscle and nonmuscle myosin light chain alkali 6", "tax_id": 9823, "disease": "", "pathway": " (ssc:396807); (R-SSC-445355); (R-SSC-5627123)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "1500421", "class_list": "", "function": "Regulatory light chain of myosin. Does not bind calcium., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "P16475;P24572;P24573;Q12790", "ec_number_list": "", "go_molecular_function": "GO:0005509 calcium ion binding;GO:0008307 structural constituent of muscle;GO:0000146 microfilament motor activity", "go_cellular_component": "GO:0016460 myosin II complex", "go_biological_process": "GO:0006936 muscle contraction;GO:0030049 muscle filament sliding", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "P60662-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P62895-1", "uniprot_id": "CYC_PIG", "mass": 11704.0, "length": 105, "protein_name": "Cytochrome c", "gene_name": "CYCS", "organism": "Pig", "refseq_name": "cytochrome c", "refseq_ac": "NP_001123442", "gene_names_uniprotkb": "CYCS; CYC", "gene_names_refseq": "CYCS; CYC", "protein_names_uniprotkb": "Cytochrome c", "protein_names_refseq": "cytochrome c", "tax_id": 9823, "disease": "", "pathway": " (ssc:100170131); (R-SSC-111457); (R-SSC-111458); (R-SSC-111459); (R-SSC-111461); (R-SSC-2151201); (R-SSC-3299685); (R-SSC-5620971); (R-SSC-5628897); (R-SSC-611105); (R-SSC-9627069); (R-SSC-9707564)", "pathway_count": 12, "publication_count": 3, "publication_id_list": "17934797;21880174;5855656", "class_list": "", "function": "Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain., [UniProtKB]; Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases (By similarity)., [UniProtKB]; Results suggest that excess or restricted protein supply during pregnancy alters expression of CYCS and leads to hypomethylation of CpG sites in promoter in liver of offspring. (5' flanking region: amino acid sequence; nucleic acid sequence homology), [RefSeq, PubMed]; Tissue expression profile analysis revealed that swine CYCS gene was highly expressed in muscle, fat and lung, moderately expressed in ovary, kidney, and liver, and weekly expressed in heart, spleen and small intestine., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "P00006;Q56P24", "ec_number_list": "", "go_molecular_function": "GO:0009055 electron transfer activity;GO:0046872 metal ion binding;GO:0020037 heme binding", "go_cellular_component": "GO:0005758 mitochondrial intermembrane space", "go_biological_process": "GO:0006915 apoptotic process;GO:0006123 mitochondrial electron transport, cytochrome c to oxygen;GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "P62895-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P63317-1", "uniprot_id": "TNNC1_PIG", "mass": 18417.0, "length": 161, "protein_name": "Troponin C, slow skeletal and cardiac muscles", "gene_name": "TNNC1", "organism": "Pig", "refseq_name": "troponin C, slow skeletal and cardiac muscles", "refseq_ac": "NP_001123715", "gene_names_uniprotkb": "TNNC1; TNNC", "gene_names_refseq": "TNNC1; TNNC", "protein_names_uniprotkb": "Troponin C, slow skeletal and cardiac muscles; TN-C", "protein_names_refseq": "TN-C; troponin C, slow skeletal and cardiac muscles", "tax_id": 9823, "disease": "", "pathway": " (ssc:100156435); (R-SSC-390522)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "2777752", "class_list": "", "function": "Troponin is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "O14800;P02590;P04463;Q4G1M5", "ec_number_list": "", "go_molecular_function": "GO:0031014 troponin T binding;GO:0042803 protein homodimerization activity;GO:0048306 calcium-dependent protein binding;GO:0051015 actin filament binding;GO:0005509 calcium ion binding", "go_cellular_component": "GO:1990584 cardiac Troponin complex", "go_biological_process": "GO:0086003 cardiac muscle cell contraction;GO:0003009 skeletal muscle contraction;GO:0060048 cardiac muscle contraction;GO:0055010 ventricular cardiac muscle tissue morphogenesis;GO:0032972 regulation of muscle filament sliding speed", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "P63317-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P68211-1", "uniprot_id": "ENSA_PIG", "mass": 13361.0, "length": 121, "protein_name": "Alpha-endosulfine", "gene_name": "ENSA", "organism": "Pig", "refseq_name": "alpha-endosulfine", "refseq_ac": "NP_999339", "gene_names_uniprotkb": "ENSA", "gene_names_refseq": "ENSA", "protein_names_uniprotkb": "Alpha-endosulfine; ARPP-19e", "protein_names_refseq": "ARPP-19e; alpha-endosulfine", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 2, "publication_id_list": "8635664;9653196", "class_list": "", "function": "Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. When phosphorylated at Ser-67 during mitosis, specifically interacts with PPP2R2D (PR55-delta) and inhibits its activity, leading to inactivation of PP2A, an essential condition to keep cyclin-B1-CDK1 activity high during M phase. Also acts as a stimulator of insulin secretion by interacting with sulfonylurea receptor (ABCC8), thereby preventing sulfonylurea from binding to its receptor and reducing K(ATP) channel currents (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "O97976;Q95105", "ec_number_list": "", "go_molecular_function": "GO:0019888 protein phosphatase regulator activity;GO:0051721 protein phosphatase 2A binding;GO:0019212 phosphatase inhibitor activity;GO:0004864 protein phosphatase inhibitor activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0000278 mitotic cell cycle;GO:0051301 cell division;GO:0000086 G2/M transition of mitotic cell cycle", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "P68211-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P79273-1", "uniprot_id": "ACADS_PIG", "mass": 44851.0, "length": 413, "protein_name": "Short-chain specific acyl-CoA dehydrogenase, mitochondrial", "gene_name": "ACADS", "organism": "Pig", "refseq_name": "short-chain specific acyl-CoA dehydrogenase, mitochondrial precursor", "refseq_ac": "NP_999063", "gene_names_uniprotkb": "ACADS", "gene_names_refseq": "ACADS", "protein_names_uniprotkb": "Short-chain specific acyl-CoA dehydrogenase, mitochondrial; 1.3.8.1; Butyryl-CoA dehydrogenase; SCAD", "protein_names_refseq": "SCAD; acyl-CoA dehydrogenase, C-2 to C-3 short chain; acyl-Coenzyme A dehydrogenase, C-2 to C-3 short chain; butyryl-CoA dehydrogenase; short-chain acyl-CoA dehydrogenase; short-chain specific acyl-CoA dehydrogenase, mitochondrial precursor; short-chain specific acyl-CoA dehydrogenase, mitochondrial", "tax_id": 9823, "disease": "", "pathway": " (ssc:396932)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Short-chain specific acyl-CoA dehydrogenase is one of the acyl-CoA dehydrogenases that catalyze the first step of mitochondrial fatty acid beta-oxidation, an aerobic process breaking down fatty acids into acetyl-CoA and allowing the production of energy from fats. The first step of fatty acid beta-oxidation consists in the removal of one hydrogen from C-2 and C-3 of the straight-chain fatty acyl-CoA thioester, resulting in the formation of trans-2-enoyl-CoA. Among the different mitochondrial acyl-CoA dehydrogenases, short-chain specific acyl-CoA dehydrogenase acts specifically on acyl-CoAs with saturated 4 to 6 carbons long primary chains., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003995 acyl-CoA dehydrogenase activity;GO:0050660 flavin adenine dinucleotide binding;GO:0016937 short-chain fatty acyl-CoA dehydrogenase activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase;GO:0046359 butyrate catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "P79273-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P79288-1", "uniprot_id": "KLF9_PIG", "mass": 27219.0, "length": 244, "protein_name": "Krueppel-like factor 9", "gene_name": "KLF9", "organism": "Pig", "refseq_name": "Krueppel-like factor 9", "refseq_ac": "NP_001011504", "gene_names_uniprotkb": "KLF9; BTEB1; BTEB", "gene_names_refseq": "BTEB1; BTEB; KLF9", "protein_names_uniprotkb": "Krueppel-like factor 9; BTE-binding protein 1; Basic transcription element-binding protein 1; GC-box-binding protein 1; Transcription factor BTEB1", "protein_names_refseq": "BTE-binding protein 1; BTEB transcription factor; GC-box-binding protein 1; Krueppel-like factor 9; Kruppel like factor 9; basic transcription element-binding protein 1; transcription factor BTEB1", "tax_id": 9823, "disease": "", "pathway": " (ssc:494562)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "28972010;9314570", "class_list": "", "function": "KLF9 was verified to be directly regulated by TH in a TH receptor (TR)-dependent manner in hypothyroid mutants, [RefSeq, PubMed]; Transcription factor that binds to GC box promoter elements. Selectively activates mRNA synthesis from genes containing tandem repeats of GC boxes but represses genes with a single GC box. Acts as an epidermal circadian transcription factor regulating keratinocyte proliferation., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q5I6A2", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0048511 rhythmic process;GO:0010839 negative regulation of keratinocyte proliferation;GO:0071387 cellular response to cortisol stimulus", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "P79288-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P79292-1", "uniprot_id": "OPRX_PIG", "mass": 40610.0, "length": 370, "protein_name": "Nociceptin receptor", "gene_name": "OPRL1", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "OPRL1", "gene_names_refseq": "", "protein_names_uniprotkb": "Nociceptin receptor; K3 opiate receptor; KOR-3; Kappa-type 3 opioid receptor; ORGC; Orphanin FQ receptor", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (ssc:397364)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "9988113", "class_list": "", "function": "G protein-coupled opioid receptor that functions as a receptor for the endogenous neuropeptide nociceptin. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling via G proteins mediates inhibition of adenylate cyclase activity and calcium channel activity. Arrestins modulate signaling via G proteins and mediate the activation of alternative signaling pathways that lead to the activation of MAP kinases. Plays a role in modulating nociception and the perception of pain. Plays a role in the regulation of locomotor activity by the neuropeptide nociceptin (By similarity)., [UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0001626 nociceptin receptor activity;GO:0004930 G protein-coupled receptor activity;GO:0042923 neuropeptide binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0031410 cytoplasmic vesicle;GO:0043005 neuron projection", "go_biological_process": "GO:0007193 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway;GO:0007218 neuropeptide signaling pathway;GO:0019233 sensory perception of pain", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "P79292-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P79295-1", "uniprot_id": "AMH_PIG", "mass": 61505.0, "length": 575, "protein_name": "Anti-Muellerian hormone", "gene_name": "AMH", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "AMH", "gene_names_refseq": "", "protein_names_uniprotkb": "Anti-Muellerian hormone; AMH; MIS; Muellerian-inhibiting factor; Muellerian-inhibiting substance", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 2, "publication_id_list": "30063719;909589", "class_list": "", "function": "The anti-Muellerian hormone (AMH) plays an important role in several reproductive functions (By similarity). Anti-Muellerian hormone binds and activates AMHR2, its specific type-II receptor, that heterodimerizes with type-I receptors (ACVR1 and BMPR1A) to regulate target gene expression through downstream SMAD protein signal transduction (By similarity). Produced and secreted by Sertoli cells of the male fetus, anti-Muellerian hormone induces Muellerian duct regression during male fetal sexual differentiation (By similarity). In female, it is produced by granulosa cells of the preantral and small antral follicles and acts as a negative regulator of the primordial to primary follicle transition and decreases FSH sensitivity of growing follicles (By similarity). Also plays a role in Leydig cell differentiation and function (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 2, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005160 transforming growth factor beta receptor binding;GO:0008083 growth factor activity;GO:0005114 type II transforming growth factor beta receptor binding", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:2000355 negative regulation of ovarian follicle development;GO:0001541 ovarian follicle development;GO:0001880 Mullerian duct regression;GO:0033327 Leydig cell differentiation;GO:0007506 gonadal mesoderm development", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "P79295-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P79304-1", "uniprot_id": "CP193_PIG", "mass": 57915.0, "length": 501, "protein_name": "Aromatase 3", "gene_name": "CYP19A3", "organism": "Pig", "refseq_name": "aromatase 3", "refseq_ac": "NP_999596", "gene_names_uniprotkb": "CYP19A3", "gene_names_refseq": "CYP19A3", "protein_names_uniprotkb": "Aromatase 3; 1.14.14.14; CYPXIXA3; Cytochrome P-450AROM; Cytochrome P450 19 type III; Estrogen synthase", "protein_names_refseq": "CYPXIXA3; aromatase 3; aromatase cytochrome P450 19A3; cytochrome P-450AROM; cytochrome P450 19 type III; cytochrome P450, family 19, subfamily A, polypeptide 3; estrogen synthase; type I cytochrome p450 aromatase", "tax_id": 9823, "disease": "", "pathway": " (ssc:403333)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "34856344;8674811;9212170;9365218", "class_list": "", "function": "Catalyzes the formation of aromatic C18 estrogens from C19 androgens., [UniProtKB]; Multifaceted epigenetic regulation of porcine testicular aromatase., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0070330 aromatase activity;GO:0005506 iron ion binding;GO:0020037 heme binding", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0016020 membrane", "go_biological_process": "GO:0032355 response to estradiol;GO:0006694 steroid biosynthetic process;GO:0008209 androgen metabolic process;GO:0008585 female gonad development", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P79304-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P79379-1", "uniprot_id": "MT2_PIG", "mass": 5970.0, "length": 61, "protein_name": "Metallothionein-2A", "gene_name": "MT2A", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "MT2A", "gene_names_refseq": "", "protein_names_uniprotkb": "Metallothionein-2A; MT-2A; MT-IIA; Metallothionein-IIA", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (ssc:396827); (R-SSC-5661231)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "9573337", "class_list": "", "function": "Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0071276 cellular response to cadmium ion;GO:0071280 cellular response to copper ion;GO:0010273 detoxification of copper ion;GO:0006882 intracellular zinc ion homeostasis;GO:0071294 cellular response to zinc ion", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "P79379-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P79381-1", "uniprot_id": "HYEP_PIG", "mass": 52394.0, "length": 454, "protein_name": "Epoxide hydrolase 1", "gene_name": "EPHX1", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "EPHX1", "gene_names_refseq": "", "protein_names_uniprotkb": "Epoxide hydrolase 1; 3.3.2.9; Epoxide hydratase; Microsomal epoxide hydrolase; mEH", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (ssc:397639); (R-SSC-211945)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water. May play a role in the metabolism of endogenous lipids such as epoxide-containing fatty acids. Metabolizes the abundant endocannabinoid 2-arachidonoylglycerol (2-AG) to free arachidonic acid (AA) and glycerol (By similarity). Binds 20(S)-hydroxycholesterol (20(S)-OHC) (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008142 oxysterol binding;GO:0004301 epoxide hydrolase activity;GO:0033961 cis-stilbene-oxide hydrolase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0009636 response to toxic substance;GO:0019369 arachidonate metabolic process;GO:0097176 epoxide metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "P79381-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P79399-1", "uniprot_id": "5HT1B_PIG", "mass": 16941.0, "length": 150, "protein_name": "5-hydroxytryptamine receptor 1B", "gene_name": "HTR1B", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "HTR1B", "gene_names_refseq": "", "protein_names_uniprotkb": "5-hydroxytryptamine receptor 1B; 5-HT-1B; 5-HT1B; Serotonin receptor 1B", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "G protein-coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for ergot alkaloid derivatives, various anxiolytic and antidepressant drugs and other psychoactive substances, such as lysergic acid diethylamide (LSD). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors, such as adenylate cyclase. HTR1B is coupled to G(i)/G(o) G alpha proteins and mediates inhibitory neurotransmission by inhibiting adenylate cyclase activity. Arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Regulates the release of 5-hydroxytryptamine, dopamine and acetylcholine in the brain, and thereby affects neural activity, nociceptive processing, pain perception, mood and behavior. Besides, plays a role in vasoconstriction of cerebral arteries., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004993 G protein-coupled serotonin receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0045202 synapse", "go_biological_process": "GO:0007268 chemical synaptic transmission;GO:0071466 cellular response to xenobiotic stimulus;GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway;GO:0014063 negative regulation of serotonin secretion;GO:0042310 vasoconstriction", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "P79399-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P79400-1", "uniprot_id": "5HT1D_PIG", "mass": 32669.0, "length": 291, "protein_name": "5-hydroxytryptamine receptor 1D", "gene_name": "HTR1D", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "HTR1D", "gene_names_refseq": "", "protein_names_uniprotkb": "5-hydroxytryptamine receptor 1D; 5-HT-1D; 5-HT1D; Serotonin receptor 1D", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "G protein-coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for ergot alkaloid derivatives, various anxiolytic and antidepressant drugs and other psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors, such as adenylate cyclase. HTR1D is coupled to G(i)/G(o) G alpha proteins and mediates inhibitory neurotransmission by inhibiting adenylate cyclase activity. Regulates the release of 5-hydroxytryptamine in the brain, and thereby affects neural activity. May also play a role in regulating the release of other neurotransmitters. May play a role in vasoconstriction., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004993 G protein-coupled serotonin receptor activity;GO:0030594 neurotransmitter receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0030425 dendrite;GO:0045202 synapse", "go_biological_process": "GO:0006939 smooth muscle contraction;GO:0007193 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway;GO:0040012 regulation of locomotion;GO:0007187 G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger;GO:0007268 chemical synaptic transmission", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "P79400-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P79401-1", "uniprot_id": "CP3AT_PIG", "mass": 57199.0, "length": 503, "protein_name": "Cytochrome P450 3A29", "gene_name": "CYP3A29", "organism": "Pig", "refseq_name": "cytochrome P450 3A29", "refseq_ac": "NP_999588", "gene_names_uniprotkb": "CYP3A29", "gene_names_refseq": "CYP3A29", "protein_names_uniprotkb": "Cytochrome P450 3A29; 1.14.14.1; CYPIIIA29", "protein_names_refseq": "CYPIIIA29; cytochrome P450 3A29; cytochrome P450, family 3, subfamily A, polypeptide 29", "tax_id": 9823, "disease": "", "pathway": " (ssc:403324)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "17548327;20863320;21447389;24525126;25413352;27626447;30153482;9682441", "class_list": "", "function": "A correlation between individual pig CYP3A mRNA expression and in vivo hepatic extraction ratio was established which indicates that CYP3A is the major determinant factor of verapamil metabolism in both pigs and humans., [RefSeq, PubMed]; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics., [UniProtKB]; Data suggest high similarity in mechanisms involved in regulation of expression of pig CYP3A29 and human CYP3A4 in hepatocytes. Expression of pregnane X receptor (PXR) is correlated with expression of CYP3A29 in pig hepatocytes., [RefSeq, PubMed]; Levels of CYP3A29 mRNA expression in livers of Bama miniature pigs, Guizhou miniature pigs and Rongchang pigs, [RefSeq, PubMed]; Pig CYP3A29 bioactivates aflatoxin B1 in regioselective manner. Publication Status: Online-Only, [RefSeq, PubMed]; Pregnane X receptor is required for interferon-alpha-mediated CYP3A29 expression, and its expression before CYP3A29., [RefSeq, PubMed]; The affinity of CYP3A29 for nifedipine was lower than that of human CYP3A4 but higher than that of pig liver microsomes., [RefSeq, PubMed]; The regulatory effect of IFN-gamma on CYP3A29 expression is mediated via PXR., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen;GO:0004497 monooxygenase activity;GO:0050649 testosterone 6-beta-hydroxylase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0071357 cellular response to type I interferon;GO:0070989 oxidative demethylation;GO:0008202 steroid metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "P79401-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P79402-1", "uniprot_id": "CP242_PIG", "mass": 37458.0, "length": 327, "protein_name": "Cytochrome P450 2C42", "gene_name": "CYP2C42", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "CYP2C42", "gene_names_refseq": "", "protein_names_uniprotkb": "Cytochrome P450 2C42; 1.14.14.1; CYPIIC42", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "9682441", "class_list": "", "function": "Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0042178 xenobiotic catabolic process;GO:0019373 epoxygenase P450 pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "P79402-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P79430-1", "uniprot_id": "CP192_PIG", "mass": 58063.0, "length": 503, "protein_name": "Aromatase 2", "gene_name": "CYP19A2", "organism": "Pig", "refseq_name": "aromatase 2", "refseq_ac": "NP_999595", "gene_names_uniprotkb": "CYP19A2", "gene_names_refseq": "CYP19A2; CYP19", "protein_names_uniprotkb": "Aromatase 2; 1.14.14.14; CYPXIXA2; Cytochrome P-450AROM; Cytochrome P450 19 type II; Estrogen synthase", "protein_names_refseq": "CYPXIXA2; aromatase 2; aromatase cytochrome P450 19A2; cytochrome P-450AROM; cytochrome P450 19 type II; cytochrome P450, family 19, subfamily A, polypeptide 2; estrogen synthase; type II cytochrome p450 aromatase", "tax_id": 9823, "disease": "", "pathway": " (ssc:403332)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "8674811;9212170", "class_list": "", "function": "Catalyzes the formation of aromatic C18 estrogens from C19 androgens., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "O02847", "ec_number_list": "", "go_molecular_function": "GO:0070330 aromatase activity;GO:0005506 iron ion binding;GO:0020037 heme binding", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0016020 membrane", "go_biological_process": "GO:0032355 response to estradiol;GO:0006694 steroid biosynthetic process;GO:0008209 androgen metabolic process;GO:0008585 female gonad development", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "P79430-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P80031-1", "uniprot_id": "GSTP1_PIG", "mass": 23497.0, "length": 207, "protein_name": "Glutathione S-transferase P", "gene_name": "GSTP1", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "GSTP1", "gene_names_refseq": "", "protein_names_uniprotkb": "Glutathione S-transferase P; 2.5.1.18; GST P1-1; GST class-pi", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 4, "publication_id_list": "2013291;2039535;2065650;7932743", "class_list": "", "function": "Catalyzes conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Involved in the formation of glutathione conjugates of both prostaglandin A2 (PGA2) and prostaglandin J2 (PGJ2). Participates in the formation of novel hepoxilin regioisomers. Acts as a negative regulator of ferroptosis by mediating glutathione conjugation and detoxification of 4-hydroxynonenal (4-HNE) reactive aldehyde. Negatively regulates CDK5 activity via p25/p35 translocation to prevent neurodegeneration., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004364 glutathione transferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005739 mitochondrion;GO:0005829 cytosol", "go_biological_process": "GO:0006693 prostaglandin metabolic process;GO:1901687 glutathione derivative biosynthetic process;GO:0051122 hepoxilin biosynthetic process;GO:0006749 glutathione metabolic process;GO:0110076 negative regulation of ferroptosis", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "P80031-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P80054-1", "uniprot_id": "PR39_PIG", "mass": 19477.0, "length": 172, "protein_name": "Antibacterial protein PR-39", "gene_name": "PR39", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "PR39", "gene_names_refseq": "", "protein_names_uniprotkb": "Antibacterial protein PR-39", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (ssc:407610)", "pathway_count": 1, "publication_count": 5, "publication_id_list": "1765098;7498526;7624374;7996056;8250863", "class_list": "", "function": "Exerts a potent antimicrobial activity against both E.coli and B.megaterium., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9TR84", "ec_number_list": "", "go_molecular_function": "GO:0001530 lipopolysaccharide binding", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0045087 innate immune response;GO:0050829 defense response to Gram-negative bacterium;GO:0050830 defense response to Gram-positive bacterium;GO:0061844 antimicrobial humoral immune response mediated by antimicrobial peptide", "synthesized_glycan_count": 0, "hit_score": 0.6, "record_id": "P80054-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P81245-1", "uniprot_id": "OBP_PIG", "mass": 17708.0, "length": 157, "protein_name": "Odorant-binding protein", "gene_name": "", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "", "gene_names_refseq": "", "protein_names_uniprotkb": "Odorant-binding protein; OBP", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 4, "publication_id_list": "25538681;30740091;9609684;9915115", "class_list": "", "function": "This protein is found in nasal epithelium and it binds a wide variety of chemical odorants., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 2, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 2, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 2, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 1, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0036094 small molecule binding;GO:0005549 odorant binding", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0007608 sensory perception of smell", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P81245-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P81405-1", "uniprot_id": "SAP_PIG", "mass": 8949.0, "length": 80, "protein_name": "Saposin-B-Val", "gene_name": "PSAP", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "PSAP", "gene_names_refseq": "", "protein_names_uniprotkb": "Saposin-B-Val; CS-ACT; Cerebroside sulfate activator; Non-specific activator; SAP-1; Sphingolipid activator protein 1", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 4, "publication_id_list": "10510427;11180632;1562358;8471613", "class_list": "", "function": "Saposins are specific low-molecular mass non-enzymatic glycoproteins that act as activator proteins for lysosomal sphingolipid-degrading enzymes, facilitating the hydrolysis of sphingolipids by extracting lipid substrates from membranes and presenting them to their respective enzymes. They are derived from a common precursor protein, prosaposin, which is proteolytically cleaved to yield four homologous proteins (saposin A, B, C, and D), each with distinct but partially overlapping lipid and enzyme specificities., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 1, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 1, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 1, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 1, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 1, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 2, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005576 extracellular region;GO:0016020 membrane;GO:0005764 lysosome;GO:0005770 late endosome", "go_biological_process": "GO:0006665 sphingolipid metabolic process;GO:0007041 lysosomal transport", "synthesized_glycan_count": 0, "hit_score": 0.8, "record_id": "P81405-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P81558-1", "uniprot_id": "MBP_PIG", "mass": 18487.0, "length": 171, "protein_name": "Myelin basic protein", "gene_name": "MBP", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "MBP", "gene_names_refseq": "", "protein_names_uniprotkb": "Myelin basic protein; MBP", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "2578056", "class_list": "", "function": "Is, with PLP, the most abundant protein component of the myelin membrane in the CNS. Has a role in both the formation and stabilization of this compact multilayer arrangement of bilayers. Each splice variant and charge isomer may have a specialized function in the assembly of an optimized, biochemically functional myelin membrane (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 15, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "P98189", "ec_number_list": "", "go_molecular_function": "GO:0019911 structural constituent of myelin sheath;GO:0005516 calmodulin binding", "go_cellular_component": "GO:0033269 internode region of axon;GO:0043025 neuronal cell body;GO:0071944 cell periphery;GO:0032991 protein-containing complex;GO:0043218 compact myelin", "go_biological_process": "GO:0042552 myelination", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "P81558-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P82460-1", "uniprot_id": "THIO_PIG", "mass": 11829.0, "length": 105, "protein_name": "Thioredoxin", "gene_name": "TXN", "organism": "Pig", "refseq_name": "thioredoxin", "refseq_ac": "NP_999478", "gene_names_uniprotkb": "TXN", "gene_names_refseq": "TRX1; TXN", "protein_names_uniprotkb": "Thioredoxin; Trx", "protein_names_refseq": "thioredoxin; trx", "tax_id": 9823, "disease": "", "pathway": " (ssc:397581)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "17406940;28087409", "class_list": "", "function": "In pigs, however not significant, there was a continuing increase in plasma-TRX after femur fracture and sequential hemorrhage despite near normalisation of cardiac index and lactate levels., [RefSeq, PubMed]; Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions (By similarity). Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. Induces the FOS/JUN AP-1 DNA binding activity in ionizing radiation (IR) cells through its oxidation/reduction status and stimulates AP-1 transcriptional activity (By similarity)., [UniProtKB]; Single-marker and haplotype analyses revealed significant effects of TXNIP on hot carcass weight, test daily gain, and lifetime daily gain, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q95JF9", "ec_number_list": "", "go_molecular_function": "GO:0015035 protein-disulfide reductase activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0005634 nucleus;GO:0005737 cytoplasm", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0019725 cellular homeostasis;GO:0009314 response to radiation;GO:0043388 positive regulation of DNA binding", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "P82460-1", "record_type": "protein" }, { "uniprot_canonical_ac": "P98110-1", "uniprot_id": "LYAM2_PIG", "mass": 52567.0, "length": 484, "protein_name": "E-selectin", "gene_name": "SELE", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "SELE", "gene_names_refseq": "", "protein_names_uniprotkb": "E-selectin; CD62 antigen-like family member E; ELAM-1; Endothelial leukocyte adhesion molecule 1; LECAM2; Leukocyte-endothelial cell adhesion molecule 2", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (ssc:397508); (R-SSC-202733)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "7516159;7526854", "class_list": "", "function": "Cell-surface glycoprotein having a role in immunoadhesion (PubMed:7526854). Mediates in the adhesion of blood neutrophils in cytokine-activated endothelium through interaction with SELPLG/PSGL1. May have a role in capillary morphogenesis (By similarity)., [UniProtKB, UniProtKB, PubMed]", "predicted_glycosites": 8, "predicted_n_glycosites": 8, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 8, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0070492 oligosaccharide binding;GO:0046872 metal ion binding;GO:0033691 sialic acid binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0009897 external side of plasma membrane", "go_biological_process": "GO:1903238 positive regulation of leukocyte tethering or rolling;GO:0034097 response to cytokine;GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules;GO:0050901 leukocyte tethering or rolling", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "P98110-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q03333-1", "uniprot_id": "NEC2_PIG", "mass": 70452.0, "length": 638, "protein_name": "Neuroendocrine convertase 2", "gene_name": "PCSK2", "organism": "Pig", "refseq_name": "neuroendocrine convertase 2 precursor", "refseq_ac": "NP_001004044", "gene_names_uniprotkb": "PCSK2; PC2", "gene_names_refseq": "PC2; PCSK2", "protein_names_uniprotkb": "Neuroendocrine convertase 2; 3.4.21.94; KEX2-like endoprotease 2; NEC 2; PC2; Prohormone convertase 2; Proprotein convertase 2", "protein_names_refseq": "KEX2-like endoprotease 2; NEC 2; neuroendocrine convertase 2 precursor; neuroendocrine convertase 2; pro-hormone convertase; prohormone convertase 2; proprotein convertase 2", "tax_id": 9823, "disease": "", "pathway": " (ssc:445533)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "1397279", "class_list": "", "function": "Serine endopeptidase which is involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. Responsible for the release of glucagon from proglucagon in pancreatic A cells. Mediates the release of insulin from proinsulin., [UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004252 serine-type endopeptidase activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0016020 membrane;GO:0043005 neuron projection;GO:0030133 transport vesicle;GO:0070013 intracellular organelle lumen", "go_biological_process": "GO:0016486 peptide hormone processing", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q03333-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q06922-1", "uniprot_id": "TGFA_PIG", "mass": 17056.0, "length": 160, "protein_name": "Protransforming growth factor alpha", "gene_name": "TGFA", "organism": "Pig", "refseq_name": "protransforming growth factor alpha precursor", "refseq_ac": "NP_999416", "gene_names_uniprotkb": "TGFA", "gene_names_refseq": "TGFA", "protein_names_uniprotkb": "Protransforming growth factor alpha; EGF-like TGF; ETGF; TGF type 1", "protein_names_refseq": "protransforming growth factor alpha precursor; protransforming growth factor alpha", "tax_id": 9823, "disease": "", "pathway": " (ssc:397484)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "18278782;8280083", "class_list": "", "function": "TGF alpha is a mitogenic polypeptide that is able to bind to the EGF receptor/EGFR and to act synergistically with TGF beta to promote anchorage-independent cell proliferation in soft agar., [UniProtKB]; Upregulation of TGFalpha or FGF2 expression is not a pre-requisite for enhanced testicular growth and increased Sertoli cell proliferation that occurs subsequent to hemicastration in the neonatal boar, [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005154 epidermal growth factor receptor binding;GO:0008083 growth factor activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005886 plasma membrane", "go_biological_process": "GO:0007166 cell surface receptor signaling pathway;GO:0008284 positive regulation of cell population proliferation;GO:0043410 positive regulation of MAPK cascade;GO:0007173 epidermal growth factor receptor signaling pathway;GO:0051781 positive regulation of cell division", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q06922-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q06AA3-1", "uniprot_id": "RGN_PIG", "mass": 33118.0, "length": 299, "protein_name": "Regucalcin", "gene_name": "RGN", "organism": "Pig", "refseq_name": "regucalcin", "refseq_ac": "NP_001070688", "gene_names_uniprotkb": "RGN; SMP30", "gene_names_refseq": "GNL; RGN; SMP-30", "protein_names_uniprotkb": "Regucalcin; 3.1.1.17; GNL; Gluconolactonase; RC; SMP-30; Senescence marker protein 30", "protein_names_refseq": "RC; gluconolactonase; regucalcin (senescence marker protein-30); regucalcin; senescence marker protein 30", "tax_id": 9823, "disease": "", "pathway": " (ssc:768107)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Gluconolactonase with low activity towards other sugar lactones, including gulonolactone and galactonolactone. Catalyzes a key step in ascorbic acid (vitamin C) biosynthesis. Can also hydrolyze diisopropyl phosphorofluoridate and phenylacetate (in vitro). Calcium-binding protein. Modulates Ca(2+) signaling, and Ca(2+)-dependent cellular processes and enzyme activities (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004341 gluconolactonase activity;GO:0008270 zinc ion binding;GO:0005509 calcium ion binding;GO:0030234 enzyme regulator activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0019853 L-ascorbic acid biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q06AA3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q06AA9-1", "uniprot_id": "UB2D2_PIG", "mass": 16737.0, "length": 147, "protein_name": "Ubiquitin-conjugating enzyme E2 D2", "gene_name": "UBE2D2", "organism": "Pig", "refseq_name": "ubiquitin-conjugating enzyme E2 D2", "refseq_ac": "NP_001072141", "gene_names_uniprotkb": "UBE2D2; UBC4; UBCH4; UBCH5B", "gene_names_refseq": "UBE2D2; UBE2D3", "protein_names_uniprotkb": "Ubiquitin-conjugating enzyme E2 D2; (E3-independent) E2 ubiquitin-conjugating enzyme D2; 2.3.2.23; 2.3.2.24; E2 ubiquitin-conjugating enzyme D2; Ubiquitin carrier protein D2; Ubiquitin-protein ligase D2", "protein_names_refseq": "(E3-independent) E2 ubiquitin-conjugating enzyme D2; E2 ubiquitin-conjugating enzyme D2; UB2D2; ubiquitin carrier protein D2; ubiquitin-conjugating enzyme E2 D2; ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast); ubiquitin-protein ligase D2", "tax_id": 9823, "disease": "", "pathway": " (ssc:780418)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "17610147", "class_list": "", "function": "Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'-linked polyubiquitination. Mediates the selective degradation of short-lived and abnormal proteins. Functions in the E6/E6-AP-induced ubiquitination of p53/TP53. Mediates ubiquitination of PEX5 and SQSTM1 and autoubiquitination of STUB1 and TRAF6. Involved in the signal-induced conjugation and subsequent degradation of NFKBIA, FBXW2-mediated GCM1 ubiquitination and degradation, MDM2-dependent degradation of p53/TP53 and the activation of MAVS in the mitochondria by RIGI in response to viral infection. Essential for viral activation of IRF3., [UniProtKB, UniProtKB]; The swine UB2D2 gene was weakly expressed in lung, and hardly expressed in small intestine, large intestine, liver, muscle, fat, spleen and kidney., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0004842 ubiquitin-protein transferase activity;GO:0061631 ubiquitin conjugating enzyme activity", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0070979 protein K11-linked ubiquitination;GO:0006511 ubiquitin-dependent protein catabolic process;GO:0070936 protein K48-linked ubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q06AA9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q06AK6-1", "uniprot_id": "TFP11_PIG", "mass": 96501.0, "length": 836, "protein_name": "Tuftelin-interacting protein 11", "gene_name": "TFIP11", "organism": "Pig", "refseq_name": "tuftelin-interacting protein 11", "refseq_ac": "NP_001070682", "gene_names_uniprotkb": "TFIP11; STIP", "gene_names_refseq": "STIP; TFIP11", "protein_names_uniprotkb": "Tuftelin-interacting protein 11; STIP-1; Septin and tuftelin-interacting protein 1", "protein_names_refseq": "STIP-1; septin and tuftelin-interacting protein 1; tuftelin-interacting protein 11", "tax_id": 9823, "disease": "", "pathway": " (ssc:768099); (R-SSC-72163)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "17289020", "class_list": "", "function": "Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events. Intron turnover seems to proceed through reactions in two lariat-intron associated complexes termed Intron Large (IL) and Intron Small (IS). In cooperation with DHX15 seems to mediate the transition of the U2, U5 and U6 snRNP-containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns. May play a role in the differentiation of ameloblasts and odontoblasts or in the forming of the enamel extracellular matrix (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003676 nucleic acid binding", "go_cellular_component": "GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0016607 nuclear speck;GO:0031012 extracellular matrix;GO:0005681 spliceosomal complex", "go_biological_process": "GO:0031333 negative regulation of protein-containing complex assembly;GO:0031214 biomineral tissue development;GO:0000390 spliceosomal complex disassembly", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q06AK6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q06AS9-1", "uniprot_id": "EFNA1_PIG", "mass": 23745.0, "length": 205, "protein_name": "Ephrin-A1", "gene_name": "EFNA1", "organism": "Pig", "refseq_name": "ephrin-A1 precursor", "refseq_ac": "NP_001116582", "gene_names_uniprotkb": "EFNA1", "gene_names_refseq": "EFNA1", "protein_names_uniprotkb": "Ephrin-A1", "protein_names_refseq": "ephrin-A1 precursor", "tax_id": 9823, "disease": "", "pathway": " (ssc:100144501)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "21656379;27775163", "class_list": "", "function": "Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. Involved in angiogenesis, regulating vascular endothelial cell differentiation and migration through activation of EPHA2. Acts as a ligand for EPHA3, inhibiting epithelial-to-mesenchymal transition of cardiac cells and playing a role in heart development. May also contribute to dendritic spine morphogenesis., [UniProtKB, UniProtKB]; Expression of Eph A1, A2, A4, and A7 was strongly detected in endometrial epithelial cells during early pregnancy., [RefSeq, PubMed]; The Eph-Ephrin A system might play an important role in regulating the swine contact between blastocysts and endometrium during embryo implantation., [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0046875 ephrin receptor binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0005886 plasma membrane;GO:0098552 side of membrane", "go_biological_process": "GO:0001525 angiogenesis;GO:0048013 ephrin receptor signaling pathway;GO:0007411 axon guidance;GO:1902533 positive regulation of intracellular signal transduction;GO:0061002 negative regulation of dendritic spine morphogenesis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q06AS9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q06AT3-1", "uniprot_id": "UCHL5_PIG", "mass": 37577.0, "length": 329, "protein_name": "Ubiquitin carboxyl-terminal hydrolase isozyme L5", "gene_name": "UCHL5", "organism": "Pig", "refseq_name": "ubiquitin carboxyl-terminal hydrolase isozyme L5", "refseq_ac": "NP_001116682", "gene_names_uniprotkb": "UCHL5", "gene_names_refseq": "UCHL5", "protein_names_uniprotkb": "Ubiquitin carboxyl-terminal hydrolase isozyme L5; 3.4.19.12; UCH-L5; Ubiquitin thioesterase L5", "protein_names_refseq": "UCH-L5; ubiquitin carboxyl-terminal hydrolase L5; ubiquitin carboxyl-terminal hydrolase isozyme L5; ubiquitin thioesterase L5", "tax_id": 9823, "disease": "", "pathway": " (ssc:100144472); (R-SSC-5689603)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Protease that specifically cleaves 'Lys-48'-linked polyubiquitin chains. Deubiquitinating enzyme associated with the 19S regulatory subunit of the 26S proteasome. Putative regulatory component of the INO80 complex; however is inactive in the INO80 complex and is activated by a transient interaction of the INO80 complex with the proteasome via ADRM1 (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0070628 proteasome binding;GO:0004843 cysteine-type deubiquitinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0031011 Ino80 complex;GO:0000502 proteasome complex", "go_biological_process": "GO:0033044 regulation of chromosome organization;GO:0006281 DNA repair;GO:0006310 DNA recombination;GO:0006351 DNA-templated transcription;GO:0016579 protein deubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q06AT3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q06AU5-1", "uniprot_id": "RAB32_PIG", "mass": 25005.0, "length": 226, "protein_name": "Ras-related protein Rab-32", "gene_name": "RAB32", "organism": "Pig", "refseq_name": "ras-related protein Rab-32", "refseq_ac": "NP_001116648", "gene_names_uniprotkb": "RAB32", "gene_names_refseq": "RAB32", "protein_names_uniprotkb": "Ras-related protein Rab-32; 3.6.5.2", "protein_names_refseq": "ras-related protein Rab-32", "tax_id": 9823, "disease": "", "pathway": " (ssc:100144496)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. Also acts as an A-kinase anchoring protein by binding to the type II regulatory subunit of protein kinase A and anchoring it to the mitochondrion. Also involved in synchronization of mitochondrial fission. Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis. Plays an important role in the control of melanin production and melanosome biogenesis (By similarity). In concert with RAB38, regulates the proper trafficking of melanogenic enzymes TYR, TYRP1 and DCT/TYRP2 to melanosomes in melanocytes (By similarity). Stimulates phosphorylation of RAB10 'Thr-73' by LRRK2 (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0046872 metal ion binding;GO:0003925 G protein activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005741 mitochondrial outer membrane;GO:0012505 endomembrane system;GO:0042470 melanosome;GO:0030670 phagocytic vesicle membrane", "go_biological_process": "GO:1903232 melanosome assembly;GO:0090382 phagosome maturation;GO:0006886 intracellular protein transport;GO:0016192 vesicle-mediated transport;GO:0032438 melanosome organization", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q06AU5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q06AU7-1", "uniprot_id": "RAB1B_PIG", "mass": 22112.0, "length": 201, "protein_name": "Ras-related protein Rab-1B", "gene_name": "RAB1B", "organism": "Pig", "refseq_name": "ras-related protein Rab-1B", "refseq_ac": "NP_001116645", "gene_names_uniprotkb": "RAB1B", "gene_names_refseq": "RAB1B", "protein_names_uniprotkb": "Ras-related protein Rab-1B; 3.6.5.2", "protein_names_refseq": "ras-related protein Rab-1B", "tax_id": 9823, "disease": "", "pathway": " (ssc:100144502)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32605744", "class_list": "", "function": "Rab1b-GBF1-ARFs mediated intracellular trafficking is required for classical swine fever virus replication in swine umbilical vein endothelial cells., [RefSeq, PubMed]; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion (By similarity). Plays a role in the initial events of the autophagic vacuole development which take place at specialized regions of the endoplasmic reticulum (By similarity). Regulates vesicular transport between the endoplasmic reticulum and successive Golgi compartments. Required to modulate the compacted morphology of the Golgi. Promotes the recruitment of lipid phosphatase MTMR6 to the endoplasmic reticulum-Golgi intermediate compartment (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0046872 metal ion binding;GO:0003925 G protein activity", "go_cellular_component": "GO:0048471 perinuclear region of cytoplasm;GO:0034045 phagophore assembly site membrane", "go_biological_process": "GO:0015031 protein transport;GO:0006914 autophagy;GO:0016192 vesicle-mediated transport;GO:0007030 Golgi organization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q06AU7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q06AV0-1", "uniprot_id": "NTF3_PIG", "mass": 29607.0, "length": 257, "protein_name": "Neurotrophin-3", "gene_name": "NTF3", "organism": "Pig", "refseq_name": "neurotrophin-3 precursor", "refseq_ac": "NP_001116624", "gene_names_uniprotkb": "NTF3", "gene_names_refseq": "NT3; NTF3", "protein_names_uniprotkb": "Neurotrophin-3; NT-3", "protein_names_refseq": "NT-3; Neurotrophin-3; neurotrophin-3 precursor", "tax_id": 9823, "disease": "", "pathway": " (ssc:100144493)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Seems to promote the survival of visceral and proprioceptive sensory neurons., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008083 growth factor activity;GO:0005163 nerve growth factor receptor binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0008021 synaptic vesicle", "go_biological_process": "GO:0007169 cell surface receptor protein tyrosine kinase signaling pathway;GO:0048812 neuron projection morphogenesis;GO:0043524 negative regulation of neuron apoptotic process;GO:0050804 modulation of chemical synaptic transmission;GO:0021675 nerve development", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q06AV0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q0PIT9-1", "uniprot_id": "NNRE_PIG", "mass": 31501.0, "length": 288, "protein_name": "NAD(P)H-hydrate epimerase", "gene_name": "NAXE", "organism": "Pig", "refseq_name": "NAD(P)H-hydrate epimerase precursor", "refseq_ac": "NP_001072132", "gene_names_uniprotkb": "NAXE; AIBP; APOA1BP", "gene_names_refseq": "APOA1BP; NAXE", "protein_names_uniprotkb": "NAD(P)H-hydrate epimerase; 5.1.99.6; AI-BP; Apolipoprotein A-I-binding protein; NAD(P)HX epimerase", "protein_names_refseq": "AI-BP; NAD(P)H-hydrate epimerase precursor; NAD(P)H-hydrate epimerase; apolipoprotein A-I-binding protein; apoliprotein A-I binding protein", "tax_id": 9823, "disease": "", "pathway": " (ssc:780405)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX. Accelerates cholesterol efflux from endothelial cells to high-density lipoprotein (HDL) and thereby regulates angiogenesis (By similarity)., [UniProtKB, HAMAP, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0046872 metal ion binding;GO:0000166 nucleotide binding;GO:0052856 NAD(P)HX epimerase activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005739 mitochondrion", "go_biological_process": "GO:0006869 lipid transport;GO:0016525 negative regulation of angiogenesis;GO:0002040 sprouting angiogenesis;GO:0010874 regulation of cholesterol efflux;GO:0046496 nicotinamide nucleotide metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q0PIT9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q19KI0-1", "uniprot_id": "RHCG_PIG", "mass": 50781.0, "length": 460, "protein_name": "Ammonium transporter Rh type C", "gene_name": "RHCG", "organism": "Pig", "refseq_name": "ammonium transporter Rh type C", "refseq_ac": "NP_001038042", "gene_names_uniprotkb": "RHCG", "gene_names_refseq": "RHCG", "protein_names_uniprotkb": "Ammonium transporter Rh type C; Rh family type C glycoprotein; Rh type C glycoprotein; Rhesus blood group family type C glycoprotein", "protein_names_refseq": "Rhesus type C glycoprotein; ammonium transporter Rh type C; rh family type C glycoprotein; rh type C glycoprotein; rhesus blood group family type C glycoprotein", "tax_id": 9823, "disease": "", "pathway": " (ssc:733644)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Ammonium transporter involved in the maintenance of acid-base homeostasis. Transports ammonium and its related derivative methylammonium across the plasma membrane of epithelial cells likely contributing to renal transepithelial ammonia transport and ammonia metabolism. Postulated to primarily mediate an electroneutral bidirectional transport of NH3 ammonia species according to a mechanism that implies interaction of an NH4(+) ion with acidic residues of the pore entry followed by dissociation of NH4(+) into NH3 and H(+). As a result NH3 transits through the central pore and is protonated on the extracellular side reforming NH4(+) (By similarity). May act as a CO2 channel providing for renal acid secretion (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008519 ammonium channel activity;GO:0035379 carbon dioxide transmembrane transporter activity;GO:0030506 ankyrin binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016323 basolateral plasma membrane;GO:0016324 apical plasma membrane;GO:0031410 cytoplasmic vesicle", "go_biological_process": "GO:0097272 ammonium homeostasis;GO:0070634 transepithelial ammonium transport;GO:0006873 intracellular monoatomic ion homeostasis;GO:0072488 ammonium transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q19KI0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q19PY3-1", "uniprot_id": "RTCB_PIG", "mass": 55238.0, "length": 505, "protein_name": "RNA-splicing ligase RTCB", "gene_name": "RTCB", "organism": "Pig", "refseq_name": "RNA-splicing ligase RTCB", "refseq_ac": "NP_001116458", "gene_names_uniprotkb": "RTCB", "gene_names_refseq": "RTCB", "protein_names_uniprotkb": "RNA-splicing ligase RTCB; 3'-phosphate/5'-hydroxy nucleic acid ligase; 6.5.1.8; RNA 2',3'-cyclic phosphate and 5'-OH ligase", "protein_names_refseq": "3'-phosphate/5'-hydroxy nucleic acid ligase; RNA-splicing ligase RTCB; RNA-splicing ligase RtcB homolog; UPF0027 protein C22orf28 homolog; tRNA-splicing ligase RtcB homolog", "tax_id": 9823, "disease": "", "pathway": " (ssc:733658)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "3'-5' RNA ligase, catalytic subunit of the tRNA-splicing ligase complex (tRNA-LC), which is involved in the enzyme-dependent maturation of intron-containing pre-tRNAs. Functions downstream of the tRNA-splicing endonuclease that removes introns, ligating the two generated halves via phosphodiester bond formation. The ligation reaction, which requires guanosine triphosphate (GTP) and Mn(2+), proceeds through three metal-dependent steps. The first step requires ZBTB8OS/Archease and involves the guanylylation of RTCB at its active site histidine, forming a covalent GMP-histidine intermediate. Before the second step, RTCB also hydrolyzes the 2',3'-cyclic phosphate (cP) at the 3' end of the 5' tRNA exon, typically generated by the tRNA-splicing endonuclease, producing a 3' phosphate. The covalently bound GMP is then transferred to this 3' phosphate to form an RNA(3')-P-P-(5')G intermediate. In the final step, the 5'-OH of the 3' exon attacks the activated 3' end of the 5' exon, forming a 3'-5' phosphodiester bond and releasing GMP. RTCB also functions in non-canonical, spliceosome-independent, cytoplasmic splicing of XBP1 mRNAs during the unfolded protein response (UPR). Upon endoplasmic reticulum (ER) stress, the endoribonuclease IRE1/ERN1 excises a short intron, generating free exon ends that are aligned by RNA-intrinsic, zipper-like stem-loop structures. These exon ends are then recognized and ligated by RTCB. This splicing event yields the active XBP1s transcription factor, which induces genes required to resolve protein folding defects in the endoplasmic reticulum., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q19PY4", "ec_number_list": "", "go_molecular_function": "GO:0005525 GTP binding;GO:0046872 metal ion binding;GO:0170057 RNA ligase (GTP) activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0072669 tRNA-splicing ligase complex", "go_biological_process": "GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q19PY3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q1KYT0-1", "uniprot_id": "ENOB_PIG", "mass": 47130.0, "length": 434, "protein_name": "Beta-enolase", "gene_name": "ENO3", "organism": "Pig", "refseq_name": "beta-enolase", "refseq_ac": "NP_001037992", "gene_names_uniprotkb": "ENO3", "gene_names_refseq": "ENO3", "protein_names_uniprotkb": "Beta-enolase; 2-phospho-D-glycerate hydro-lyase; 4.2.1.11; Enolase 3; MSE; Muscle-specific enolase; Skeletal muscle enolase", "protein_names_refseq": "2-phospho-D-glycerate hydro-lyase; MSE; beta-enolase 3; beta-enolase; muscle-specific enolase; skeletal muscle enolase", "tax_id": 9823, "disease": "", "pathway": " (ssc:692156)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "18694551;21347838", "class_list": "", "function": "Enolase that catalyzes the conversion of 2-phosphoglycerate to phosphoenolpyruvate in glycolysis and the reverse reaction in gluconeogenesis. Appears to have a function in striated muscle development and regeneration., [UniProtKB, UniProtKB]; Existence of a polymorphism in the ENO3 gene that it is associated with fat percentage, average backfat thickness, meat marbling and intramuscular fat in two different populations., [RefSeq, PubMed]; Pyridoxamine and carnosine protected enolase against the total loss of catalytic activity., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 8, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0004634 phosphopyruvate hydratase activity", "go_cellular_component": "GO:0000015 phosphopyruvate hydratase complex", "go_biological_process": "GO:0006096 glycolytic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q1KYT0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q1RPR6-1", "uniprot_id": "ITB6_PIG", "mass": 85972.0, "length": 788, "protein_name": "Integrin beta-6", "gene_name": "ITGB6", "organism": "Pig", "refseq_name": "integrin beta-6 precursor", "refseq_ac": "NP_001090892", "gene_names_uniprotkb": "ITGB6", "gene_names_refseq": "ITGB6", "protein_names_uniprotkb": "Integrin beta-6", "protein_names_refseq": "integrin beta-6 precursor; integrin, beta 6", "tax_id": 9823, "disease": "", "pathway": " (ssc:100037276)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "20438833;34519117", "class_list": "", "function": "Data show that integrin alphav, beta3, beta6 and beta8 subunit shares common structural and functional elements., [RefSeq, PubMed]; ITGB6 inhibits the proliferation of porcine skeletal muscle satellite cells., [RefSeq, PubMed]; Integrin alpha-V:beta-6 (ITGAV:ITGB6) is a receptor for fibronectin and cytotactin (By similarity). It recognizes the sequence R-G-D in its ligands (By similarity). ITGAV:ITGB6 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1 (By similarity). Integrin alpha-V:beta-6 (ITGAV:ITGB6) mediates R-G-D-dependent release of transforming growth factor beta-1 (TGF-beta-1) from regulatory Latency-associated peptide (LAP), thereby playing a key role in TGF-beta-1 activation (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 7, "predicted_n_glycosites": 7, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 7, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005178 integrin binding;GO:0015026 coreceptor activity;GO:0046872 metal ion binding;GO:0001618 virus receptor activity", "go_cellular_component": "GO:0005925 focal adhesion;GO:0009986 cell surface;GO:0034685 integrin alphav-beta6 complex", "go_biological_process": "GO:0007229 integrin-mediated signaling pathway;GO:0016477 cell migration;GO:0007160 cell-matrix adhesion;GO:0033627 cell adhesion mediated by integrin;GO:0098609 cell-cell adhesion", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q1RPR6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q28949-1", "uniprot_id": "MA2B2_PIG", "mass": 114230.0, "length": 995, "protein_name": "Epididymis-specific alpha-mannosidase", "gene_name": "MAN2B2", "organism": "Pig", "refseq_name": "epididymis-specific alpha-mannosidase precursor", "refseq_ac": "NP_999014", "gene_names_uniprotkb": "MAN2B2", "gene_names_refseq": "MAN2B2", "protein_names_uniprotkb": "Epididymis-specific alpha-mannosidase; 3.2.1.24; Core-specific lysosomal alpha-1,6-Mannosidase; Epman; Mannosidase alpha class 2B member 2", "protein_names_refseq": "135 kDa alpha-D-mannosidase; 135kDa alpha-D-mannosidase; Epididymis-specific alpha-mannosidase; core-specific lysosomal alpha-1,6-Mannosidase; epididymis-specific alpha-mannosidase precursor; epman", "tax_id": 9823, "disease": "", "pathway": " (ssc:396847)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "18680493;8562059", "class_list": "", "function": "Either MAN2B2 has a unique epistatic interaction within the Meishan-cross population or the c.1574A>G SNP is in linkage disequilibrium with the actual causative genetic variation in the Meishan-cross population., [RefSeq, PubMed]; Specifically cleaves terminal alpha 1,6-linked mannose residues on Man3GlcNAc and Man2GlcNAc core oligosaccharides generated by N-glycan degradation pathways, having little activity, if any, on larger mannose oligosaccharides. Does not cleave terminal alpha 1,6-linked mannose on Man3GlcNAc2, and is also unable to hydrolyze terminal alpha 1,3-mannose linkages., [UniProtKB, UniProtKB]", "predicted_glycosites": 8, "predicted_n_glycosites": 8, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 8, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0046872 metal ion binding;GO:0030246 carbohydrate binding;GO:0004559 alpha-mannosidase activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0005764 lysosome", "go_biological_process": "GO:0006013 mannose metabolic process;GO:0006516 glycoprotein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q28949-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q28990-1", "uniprot_id": "OVGP1_PIG", "mass": 58519.0, "length": 527, "protein_name": "Oviduct-specific glycoprotein", "gene_name": "OVGP1", "organism": "Pig", "refseq_name": "oviduct-specific glycoprotein precursor", "refseq_ac": "NP_999235", "gene_names_uniprotkb": "OVGP1; OGP", "gene_names_refseq": "OVGP1", "protein_names_uniprotkb": "Oviduct-specific glycoprotein; Estrogen-dependent oviduct protein; Oviductal glycoprotein; Oviductin; POSP-E3", "protein_names_refseq": "POSP-E3; estrogen-dependent oviduct protein; oviduct-specific glycoprotein precursor; oviduct-specific glycoprotein; oviductal glycoprotein 1, 120kDa (mucin 9, oviductin); oviductal secretory glycoprotein; oviductin", "tax_id": 9823, "disease": "", "pathway": " (ssc:397140)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "16717459;27601270;8949888", "class_list": "", "function": "Assigned to porcine chromosome 4., [RefSeq, PubMed]; Binds to oocyte zona pellucida in vivo. May play a role in the fertilization process and/or early embryonic development., [UniProtKB]; The presence or absence of conserved regions in the C-terminus of OVGP1 modify its association with the zona pellucida that affects matrix structure and renders the zona matrix permissive to sperm penetration and OVGP1 endocytosis into the egg. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 5, "predicted_n_glycosites": 3, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004568 chitinase activity;GO:0008061 chitin binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0030133 transport vesicle", "go_biological_process": "GO:0005975 carbohydrate metabolic process;GO:0007338 single fertilization;GO:0006032 chitin catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q28990-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q28998-1", "uniprot_id": "ADRB1_PIG", "mass": 50098.0, "length": 468, "protein_name": "Beta-1 adrenergic receptor", "gene_name": "ADRB1", "organism": "Pig", "refseq_name": "beta-1 adrenergic receptor", "refseq_ac": "NP_001116546", "gene_names_uniprotkb": "ADRB1", "gene_names_refseq": "ADRB1", "protein_names_uniprotkb": "Beta-1 adrenergic receptor; Beta-1 adrenoceptor; Beta-1 adrenoreceptor", "protein_names_refseq": "adrenergic, beta-1-, receptor; beta 1 adrenergic protein; beta-1 adrenergic receptor; beta-1 adrenoceptor; beta-1 adrenoreceptor", "tax_id": 9823, "disease": "", "pathway": " (ssc:397355)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "10229356;20035031;38970835;9655595", "class_list": "", "function": "Beta(1)- and beta(2)-adrenoceptors contribute to the beta-feedforward coronary resistance vessel dilation during exercise., [RefSeq, PubMed]; Differential expression of ADRB1 causes different responses to norepinephrine in adipocytes of Duroc-Landrace-Yorkshire pigs and min pigs., [RefSeq, PubMed]; G protein-coupled receptor for catecholamines that couples to G(s) proteins to activate adenylate cyclase and cAMP-dependent pathway. Binds epinephrine and norepinephrine with approximately equal affinity. Mediates the activation of Ras via binding with cAMP-dependent RAPGEF2. As part of the sympathetic nervous system, plays a role in the physiologic regulation of cardiac functions such as stimulation of cardiomyocyte contraction (By similarity). Also delivers proapoptotic signals in cardiomyocytes (By similarity). Involved in the regulation of sleep/wake behaviors (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "O46575", "ec_number_list": "", "go_molecular_function": "GO:0004940 beta1-adrenergic receptor activity", "go_cellular_component": "GO:0005769 early endosome;GO:0005886 plasma membrane", "go_biological_process": "GO:0045187 regulation of circadian sleep/wake cycle, sleep;GO:0043410 positive regulation of MAPK cascade;GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway;GO:0002025 norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure;GO:0010666 positive regulation of cardiac muscle cell apoptotic process", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q28998-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q29000-1", "uniprot_id": "IGF1R_PIG", "mass": 34615.0, "length": 304, "protein_name": "Insulin-like growth factor 1 receptor", "gene_name": "IGF1R", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "IGF1R", "gene_names_refseq": "", "protein_names_uniprotkb": "Insulin-like growth factor 1 receptor; 2.7.10.1; IGF-I receptor; Insulin-like growth factor I receptor", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "7649105", "class_list": "", "function": "Receptor tyrosine kinase which mediates actions of insulin-like growth factor 1 (IGF1). Binds IGF1 with high affinity and IGF2 and insulin (INS) with a lower affinity. The activated IGF1R is involved in cell growth and survival control. IGF1R is crucial for tumor transformation and survival of malignant cell. Ligand binding activates the receptor kinase, leading to receptor autophosphorylation, and tyrosines phosphorylation of multiple substrates, that function as signaling adapter proteins including, the insulin-receptor substrates (IRS1/2), Shc and 14-3-3 proteins. Phosphorylation of IRSs proteins lead to the activation of two main signaling pathways: the PI3K-AKT/PKB pathway and the Ras-MAPK pathway. The result of activating the MAPK pathway is increased cellular proliferation, whereas activating the PI3K pathway inhibits apoptosis and stimulates protein synthesis. Phosphorylated IRS1 can activate the 85 kDa regulatory subunit of PI3K (PIK3R1), leading to activation of several downstream substrates, including protein AKT/PKB. AKT phosphorylation, in turn, enhances protein synthesis through mTOR activation and triggers the antiapoptotic effects of IGFIR through phosphorylation and inactivation of BAD. In parallel to PI3K-driven signaling, recruitment of Grb2/SOS by phosphorylated IRS1 or Shc leads to recruitment of Ras and activation of the ras-MAPK pathway. In addition to these two main signaling pathways IGF1R signals also through the Janus kinase/signal transducer and activator of transcription pathway (JAK/STAT). Phosphorylation of JAK proteins can lead to phosphorylation/activation of signal transducers and activators of transcription (STAT) proteins. In particular activation of STAT3, may be essential for the transforming activity of IGF1R. The JAK/STAT pathway activates gene transcription and may be responsible for the transforming activity. JNK kinases can also be activated by the IGF1R. IGF1 exerts inhibiting activities on JNK activation via phosphorylation and inhibition of MAP3K5/ASK1, which is able to directly associate with the IGF1R (By similarity). When present in a hybrid receptor with INSR, binds IGF1 (By similarity)., [UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "Q28951", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0004714 transmembrane receptor protein tyrosine kinase activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0043066 negative regulation of apoptotic process;GO:0043409 negative regulation of MAPK cascade;GO:0046328 regulation of JNK cascade", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q29000-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q29013-1", "uniprot_id": "PO2F2_PIG", "mass": 51099.0, "length": 478, "protein_name": "POU domain, class 2, transcription factor 2", "gene_name": "POU2F2", "organism": "Pig", "refseq_name": "POU domain, class 2, transcription factor 2", "refseq_ac": "NP_999205", "gene_names_uniprotkb": "POU2F2; OCT2; OTF2", "gene_names_refseq": "OCT2; POU2F2", "protein_names_uniprotkb": "POU domain, class 2, transcription factor 2; Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2; OTF-2; Oct-2; Octamer-binding protein 2; Octamer-binding transcription factor 2", "protein_names_refseq": "OTF-2; POU domain, class 2, transcription factor 2; POU-domain protein; lymphoid-restricted immunoglobulin octamer-binding protein NF-A2; oct-2; octamer-binding protein 2; octamer-binding transcription factor 2", "tax_id": 9823, "disease": "", "pathway": " (ssc:397105)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "7943947;8270542", "class_list": "", "function": "Transcription factor that specifically binds to the octamer motif (5'-ATTTGCAT-3'). Regulates IL6 expression in B cells with POU2AF1. Regulates transcription in a number of tissues in addition to activating immunoglobulin gene expression. Modulates transcription transactivation by NR3C1, AR and PGR., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q29089", "ec_number_list": "", "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0000976 transcription cis-regulatory region binding;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0032755 positive regulation of interleukin-6 production;GO:0098586 cellular response to virus", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q29013-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q29026-1", "uniprot_id": "CEND_PIG", "mass": 13968.0, "length": 140, "protein_name": "Cell cycle exit and neuronal differentiation protein 1", "gene_name": "CEND1", "organism": "Pig", "refseq_name": "cell cycle exit and neuronal differentiation protein 1", "refseq_ac": "NP_999031", "gene_names_uniprotkb": "CEND1; BM88", "gene_names_refseq": "BM88; CEND1", "protein_names_uniprotkb": "Cell cycle exit and neuronal differentiation protein 1; BM88 antigen", "protein_names_refseq": "BM88 antigen; cell cycle exit and neuronal differentiation protein 1", "tax_id": 9823, "disease": "", "pathway": " (ssc:396876)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "16893893;19911428;7775480", "class_list": "", "function": "BM88 plays an essential role in regulating cell cycle exit and differentiation of Neuro 2a cells toward a neuronal phenotype, [RefSeq, PubMed]; Involved in neuronal differentiation., [UniProtKB, PubMed]; Transplantation of BM88/Cend1-overexpressing neural progenitor cells exerts beneficial effects on tissue regeneration by enhancing the number of generated neurons and restricting the formation of astroglial scar, in a mouse model of cortical brain injury., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005886 plasma membrane;GO:0012505 endomembrane system;GO:0031982 vesicle", "go_biological_process": "GO:0021686 cerebellar granular layer maturation;GO:0021933 radial glia guided migration of cerebellar granule cell;GO:0021702 cerebellar Purkinje cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q29026-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q29041-1", "uniprot_id": "FCN2_PIG", "mass": 34682.0, "length": 323, "protein_name": "Ficolin-2", "gene_name": "FCN2", "organism": "Pig", "refseq_name": "ficolin-2 precursor", "refseq_ac": "NP_999033", "gene_names_uniprotkb": "FCN2", "gene_names_refseq": "FCN2", "protein_names_uniprotkb": "Ficolin-2; Collagen/fibrinogen domain-containing protein 2; Ficolin-B; Ficolin-beta; L-ficolin", "protein_names_refseq": "L-ficolin; collagen/fibrinogen domain-containing protein 2; ficolin alpha; ficolin-2 precursor; ficolin-2; ficolin-B; ficolin-beta", "tax_id": 9823, "disease": "", "pathway": " (ssc:396881)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "7686157", "class_list": "", "function": "Calcium-dependent lectin, which acts as a pattern recognition receptor that initiates the lectin pathway of the complement system, a cascade of proteins that leads to phagocytosis and breakdown of pathogens and signaling that strengthens the adaptive immune system. Specifically recognizes and binds carbohydrates on the pathogen surface, activating the MASP1 serine protease and initiating the proteolytic cascade of the lectin complement pathway. Specifically binds N-Acetylglucosamine (GlcNAc), as well as phosphocholine and lipoteichoic acid moieties on the surface of pathogens., [UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005102 signaling receptor binding;GO:0046872 metal ion binding;GO:0030246 carbohydrate binding;GO:0070892 lipoteichoic acid immune receptor activity;GO:0003823 antigen binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0009986 cell surface;GO:0031012 extracellular matrix;GO:0106139 symbiont cell surface", "go_biological_process": "GO:0001867 complement activation, lectin pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q29041-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q29042-1", "uniprot_id": "FCN1_PIG", "mass": 35246.0, "length": 326, "protein_name": "Ficolin-1", "gene_name": "FCN1", "organism": "Pig", "refseq_name": "ficolin-1 precursor", "refseq_ac": "NP_999325", "gene_names_uniprotkb": "FCN1", "gene_names_refseq": "FCN1; FCNB", "protein_names_uniprotkb": "Ficolin-1; Ficolin-A; Ficolin-alpha", "protein_names_refseq": "ficolin B; ficolin-1 precursor; ficolin-1; ficolin-A; ficolin-alpha", "tax_id": 9823, "disease": "", "pathway": " (ssc:397316)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "7686157", "class_list": "", "function": "Extracellular lectin, which acts as a pattern recognition receptor that initiates the lectin pathway of the complement system, a cascade of proteins that leads to phagocytosis and breakdown of pathogens and signaling that strengthens the adaptive immune system. Specifically recognizes and binds carbohydrates on the pathogen surface, activating the MASP1 serine protease and initiating the proteolytic cascade of the lectin complement pathway. Binds preferentially to 9-O-acetylated 2-6-linked sialic acid derivatives and to various glycans containing sialic acid engaged in a 2-3 linkage. May also activate monocytes through a G protein-coupled receptor, FFAR2, inducing the secretion of interleukin-8/IL-8., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005102 signaling receptor binding;GO:0046872 metal ion binding;GO:0030246 carbohydrate binding;GO:0033691 sialic acid binding;GO:0003823 antigen binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0009986 cell surface;GO:0031012 extracellular matrix;GO:0106139 symbiont cell surface", "go_biological_process": "GO:0001867 complement activation, lectin pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q29042-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q29074-1", "uniprot_id": "NGF_PIG", "mass": 25276.0, "length": 229, "protein_name": "Beta-nerve growth factor", "gene_name": "NGF", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "NGF; NGFB", "gene_names_refseq": "", "protein_names_uniprotkb": "Beta-nerve growth factor; Beta-NGF", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "8039422", "class_list": "", "function": "Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades to regulate neuronal proliferation, differentiation and survival (By similarity). The immature NGF precursor (proNGF) functions as a ligand for the heterodimeric receptor formed by SORCS2 and NGFR, and activates cellular signaling cascades that lead to inactivation of RAC1 and/or RAC2, reorganization of the actin cytoskeleton and neuronal growth cone collapse. In contrast to mature NGF, the precursor form (proNGF) promotes neuronal apoptosis (in vitro) (By similarity). Inhibits metalloproteinase-dependent proteolysis of platelet glycoprotein VI (By similarity). Binds lysophosphatidylinositol and lysophosphatidylserine between the two chains of the homodimer. The lipid-bound form promotes histamine relase from mast cells, contrary to the lipid-free form (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008289 lipid binding;GO:0008083 growth factor activity;GO:0005163 nerve growth factor receptor binding;GO:0008191 metalloendopeptidase inhibitor activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0031904 endosome lumen;GO:0008021 synaptic vesicle", "go_biological_process": "GO:0007169 cell surface receptor protein tyrosine kinase signaling pathway;GO:0048812 neuron projection morphogenesis;GO:0043524 negative regulation of neuron apoptotic process;GO:0050804 modulation of chemical synaptic transmission;GO:0021675 nerve development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q29074-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q29075-1", "uniprot_id": "NKL_PIG", "mass": 14317.0, "length": 129, "protein_name": "Antimicrobial peptide NK-lysin", "gene_name": "NKL", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "NKL", "gene_names_refseq": "", "protein_names_uniprotkb": "Antimicrobial peptide NK-lysin; NKL", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 2, "publication_id_list": "7737114;9334742", "class_list": "", "function": "May be an effector molecule of cytotoxic activity. High activity against E.coli and B.megaterium, moderate against A.calcoaceticus and S.pyogenes. No activity against P.aeruginosa, S.aureus and Salmonella. Has some antifungal activity against C.albicans., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "GO:0006629 lipid metabolic process;GO:0061844 antimicrobial humoral immune response mediated by antimicrobial peptide;GO:0042742 defense response to bacterium;GO:0031640 killing of cells of another organism;GO:0050832 defense response to fungus", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q29075-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q29076-1", "uniprot_id": "PO2F1_PIG", "mass": 76596.0, "length": 745, "protein_name": "POU domain, class 2, transcription factor 1", "gene_name": "POU2F1", "organism": "Pig", "refseq_name": "POU domain, class 2, transcription factor 1", "refseq_ac": "NP_999429", "gene_names_uniprotkb": "POU2F1; OTF1", "gene_names_refseq": "OTF1; POU2F1", "protein_names_uniprotkb": "POU domain, class 2, transcription factor 1; NF-A1; OTF-1; Oct-1; Octamer-binding protein 1; Octamer-binding transcription factor 1", "protein_names_refseq": "NF-A1; OTF-1; POU domain, class 2, transcription factor 1; oct-1; octamer binding protein 1; octamer-binding transcription factor 1", "tax_id": 9823, "disease": "", "pathway": " (ssc:397501)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "8535082", "class_list": "", "function": "Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes such as those for histone H2B and immunoglobulins. Modulates transcription transactivation by NR3C1, AR and PGR., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0043565 sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0045892 negative regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q29076-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q29081-1", "uniprot_id": "PMVK_PIG", "mass": 21943.0, "length": 192, "protein_name": "Phosphomevalonate kinase", "gene_name": "PMVK", "organism": "Pig", "refseq_name": "phosphomevalonate kinase", "refseq_ac": "NP_001161888", "gene_names_uniprotkb": "PMVK", "gene_names_refseq": "PMVK", "protein_names_uniprotkb": "Phosphomevalonate kinase; 2.7.4.2; PMKase", "protein_names_refseq": "PMKase; phosphomevalonate kinase", "tax_id": 9823, "disease": "", "pathway": " (ssc:100152301); (R-SSC-9969896)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "6248100;7814412;8663599", "class_list": "", "function": "Catalyzes the reversible ATP-dependent phosphorylation of mevalonate 5-phosphate to produce mevalonate diphosphate and ADP, a key step in the mevalonic acid mediated biosynthesis of isopentenyl diphosphate and other polyisoprenoid metabolites., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "F1RGP9", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0004631 phosphomevalonate kinase activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0006695 cholesterol biosynthetic process;GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway;GO:0033386 geranylgeranyl diphosphate biosynthetic process;GO:0033489 cholesterol biosynthetic process via desmosterol;GO:0033490 cholesterol biosynthetic process via lathosterol", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q29081-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q29087-1", "uniprot_id": "PO3F3_PIG", "mass": 14724.0, "length": 131, "protein_name": "POU domain, class 3, transcription factor 3", "gene_name": "POU3F3", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "POU3F3; BRN1", "gene_names_refseq": "", "protein_names_uniprotkb": "POU domain, class 3, transcription factor 3; Brain-1; Brain-specific homeobox/POU domain protein 1; Brn-1", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Transcription factor that acts synergistically with SOX11 and SOX4. Plays a role in neuronal development. Is implicated in an enhancer activity at the embryonic met-mesencephalic junction; the enhancer element contains the octamer motif (5'-ATTTGCAT-3') (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003700 DNA-binding transcription factor activity;GO:0042803 protein homodimerization activity;GO:0043565 sequence-specific DNA binding", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0072218 metanephric ascending thin limb development;GO:0006351 DNA-templated transcription;GO:0007399 nervous system development;GO:0008284 positive regulation of cell population proliferation;GO:0010628 positive regulation of gene expression", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q29087-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q29095-1", "uniprot_id": "PTGDS_PIG", "mass": 20568.0, "length": 189, "protein_name": "Prostaglandin-H2 D-isomerase", "gene_name": "PTGDS", "organism": "Pig", "refseq_name": "prostaglandin-H2 D-isomerase precursor", "refseq_ac": "NP_999393", "gene_names_uniprotkb": "PTGDS", "gene_names_refseq": "PTGDS", "protein_names_uniprotkb": "Prostaglandin-H2 D-isomerase; 5.3.99.2; Glutathione-independent PGD synthase; Lipocalin-type prostaglandin-D synthase; PGD2 synthase; PGDS2; PGDS; Prostaglandin-D2 synthase", "protein_names_refseq": "PGD2 synthase; PGDS2; PGDS; glutathione-independent PGD synthase; glutathione-independent PGD synthetase; lipocalin-type prostaglandin-D synthase; prostaglandin D synthase; prostaglandin-H2 D-isomerase precursor; prostaglandin-H2 D-isomerase", "tax_id": 9823, "disease": "", "pathway": " (ssc:397456)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "8761996;8908190", "class_list": "", "function": "Catalyzes the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation. Involved in a variety of CNS functions, such as sedation, NREM sleep and PGE2-induced allodynia, and may have an anti-apoptotic role in oligodendrocytes. Binds small non-substrate lipophilic molecules, including biliverdin, bilirubin, retinal, retinoic acid and thyroid hormone, and may act as a scavenger for harmful hydrophobic molecules and as a secretory retinoid and thyroid hormone transporter. Possibly involved in development and maintenance of the blood-brain, blood-retina, blood-aqueous humor and blood-testis barrier. It is likely to play important roles in both maturation and maintenance of the central nervous system and male reproductive system (By similarity). Involved in PLA2G3-dependent maturation of mast cells. PLA2G3 is secreted by immature mast cells and acts on nearby fibroblasts upstream to PTDGS to synthesize PGD2, which in turn promotes mast cell maturation and degranulation via PTGDR (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 2, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004667 prostaglandin-D synthase activity;GO:0036094 small molecule binding;GO:0005501 retinoid binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0005615 extracellular space;GO:0005791 rough endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0031965 nuclear membrane", "go_biological_process": "GO:0045187 regulation of circadian sleep/wake cycle, sleep;GO:0001516 prostaglandin biosynthetic process;GO:0043303 mast cell degranulation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q29095-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q29118-1", "uniprot_id": "CSF2_PIG", "mass": 16254.0, "length": 144, "protein_name": "Granulocyte-macrophage colony-stimulating factor", "gene_name": "CSF2", "organism": "Pig", "refseq_name": "granulocyte-macrophage colony-stimulating factor precursor", "refseq_ac": "NP_999283", "gene_names_uniprotkb": "CSF2", "gene_names_refseq": "CSF2; GM-CSF", "protein_names_uniprotkb": "Granulocyte-macrophage colony-stimulating factor; CSF; Colony-stimulating factor; GM-CSF", "protein_names_refseq": "CSF; granulocyte-macrophage colony-stimulating factor precursor; granulocyte-macrophage colony-stimulating factor", "tax_id": 9823, "disease": "", "pathway": " (ssc:397208); (R-SSC-512988); (R-SSC-5673001); (R-SSC-912526)", "pathway_count": 4, "publication_count": 2, "publication_id_list": "24520418;8595928", "class_list": "", "function": "CSF2 stimulates proliferation of trophectoderm cells by activation of the PI3K-and ERK1/2 MAPK-dependent MTOR signal transduction cascades. Publication Status: Online-Only, [RefSeq, PubMed]; Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes., [UniProtKB]", "predicted_glycosites": 5, "predicted_n_glycosites": 3, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "Q29046", "ec_number_list": "", "go_molecular_function": "GO:0005129 granulocyte macrophage colony-stimulating factor receptor binding;GO:0005125 cytokine activity;GO:0008083 growth factor activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:1904075 positive regulation of trophectodermal cell proliferation;GO:0006955 immune response;GO:0051897 positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction;GO:0070374 positive regulation of ERK1 and ERK2 cascade;GO:0031929 TOR signaling", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q29118-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q29175-1", "uniprot_id": "S39A7_PIG", "mass": 50148.0, "length": 473, "protein_name": "Zinc transporter SLC39A7", "gene_name": "SLC39A7", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "SLC39A7; HKE4", "gene_names_refseq": "", "protein_names_uniprotkb": "Zinc transporter SLC39A7; Histidine-rich membrane protein Ke4; Solute carrier family 39 member 7; ZIP7; Zrt-, Irt-like protein 7", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-442380)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "8672129", "class_list": "", "function": "Transports Zn(2+) from the endoplasmic reticulum (ER)/Golgi apparatus to the cytosol, playing an essential role in the regulation of cytosolic zinc levels. Acts as a gatekeeper of zinc release from intracellular stores, requiring post-translational activation by phosphorylation on residues, resulting in activation of multiple downstream pathways leading to cell growth and proliferation. Has an essential role in B cell development and is required for proper B cell receptor signaling (By similarity). Plays an important role in maintaining intestinal epithelial homeostasis and skin dermis development by regulating ER function. Controls cell signaling pathways involved in glucose metabolism in skeletal muscle (By similarity). Has a protective role against ER stress in different biological contexts. Mediates Zn(2+)-induced ferroptosis (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "F1RZW9;Q9XT01", "ec_number_list": "", "go_molecular_function": "GO:0005385 zinc ion transmembrane transporter activity", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0071577 zinc ion transmembrane transport;GO:0098773 skin epidermis development;GO:0030183 B cell differentiation;GO:0006882 intracellular zinc ion homeostasis;GO:0110075 regulation of ferroptosis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q29175-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q29195-1", "uniprot_id": "RL10_PIG", "mass": 24603.0, "length": 214, "protein_name": "Large ribosomal subunit protein uL16", "gene_name": "RPL10", "organism": "Pig", "refseq_name": "large ribosomal subunit protein uL16", "refseq_ac": "NP_001038008", "gene_names_uniprotkb": "RPL10; QM", "gene_names_refseq": "RPL10", "protein_names_uniprotkb": "Large ribosomal subunit protein uL16; 60S ribosomal protein L10; Protein QM homolog; Ribosomal protein L10", "protein_names_refseq": "60S ribosomal protein L10; large ribosomal subunit protein uL16; protein QM homolog", "tax_id": 9823, "disease": "", "pathway": " (ssc:733593); (R-SSC-156827); (R-SSC-1799339); (R-SSC-6791226); (R-SSC-72689); (R-SSC-72706); (R-SSC-975956); (R-SSC-975957); (R-SSC-9954709); (R-SSC-9954714); (R-SSC-9954716)", "pathway_count": 11, "publication_count": 1, "publication_id_list": "8672129", "class_list": "", "function": "Component of the large ribosomal subunit. Plays a role in the formation of actively translating ribosomes. May play a role in the embryonic brain development., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q29322;Q2YGT8", "ec_number_list": "", "go_molecular_function": "GO:0045182 translation regulator activity;GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0098556 cytoplasmic side of rough endoplasmic reticulum membrane;GO:0022625 cytosolic large ribosomal subunit;GO:0015934 large ribosomal subunit", "go_biological_process": "GO:0006412 translation;GO:1990403 embryonic brain development;GO:0002181 cytoplasmic translation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q29195-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q29205-1", "uniprot_id": "RL11_PIG", "mass": 20212.0, "length": 178, "protein_name": "Large ribosomal subunit protein uL5", "gene_name": "RPL11", "organism": "Pig", "refseq_name": "large ribosomal subunit protein uL5", "refseq_ac": "NP_001001638", "gene_names_uniprotkb": "RPL11", "gene_names_refseq": "RPL11", "protein_names_uniprotkb": "Large ribosomal subunit protein uL5; 60S ribosomal protein L11", "protein_names_refseq": "60S ribosomal protein L11; large ribosomal subunit protein uL5", "tax_id": 9823, "disease": "", "pathway": " (ssc:414422)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "8672129", "class_list": "", "function": "Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel. As part of the 5S RNP/5S ribonucleoprotein particle it is an essential component of the LSU, required for its formation and the maturation of rRNAs. It also couples ribosome biogenesis to p53/TP53 activation. As part of the 5S RNP it accumulates in the nucleoplasm and inhibits MDM2, when ribosome biogenesis is perturbed, mediating the stabilization and the activation of TP53. Promotes nucleolar location of PML., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q6QAS7;Q6QDB2", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding;GO:0019843 rRNA binding;GO:0003735 structural constituent of ribosome", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0098556 cytoplasmic side of rough endoplasmic reticulum membrane;GO:0022625 cytosolic large ribosomal subunit", "go_biological_process": "GO:0006412 translation;GO:0034504 protein localization to nucleus;GO:1901798 positive regulation of signal transduction by p53 class mediator;GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q29205-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q29290-1", "uniprot_id": "CYTB_PIG", "mass": 11131.0, "length": 98, "protein_name": "Cystatin-B", "gene_name": "CSTB", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "CSTB; CST6; STFB", "gene_names_refseq": "", "protein_names_uniprotkb": "Cystatin-B; Stefin-B", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-6798695)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "8672129;8898076", "class_list": "", "function": "This is an intracellular thiol proteinase inhibitor., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0002020 protease binding;GO:0004869 cysteine-type endopeptidase inhibitor activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0005730 nucleolus;GO:0005829 cytosol", "go_biological_process": "GO:1990000 amyloid fibril formation;GO:0045861 negative regulation of proteolysis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q29290-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q29318-1", "uniprot_id": "DHSO_PIG", "mass": 10327.0, "length": 97, "protein_name": "Sorbitol dehydrogenase", "gene_name": "SORD", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "SORD", "gene_names_refseq": "", "protein_names_uniprotkb": "Sorbitol dehydrogenase; 1.1.1.-; 1.1.1.14; 1.1.1.9; L-iditol 2-dehydrogenase; Polyol dehydrogenase; SDH; XDH; Xylitol dehydrogenase", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "8672129", "class_list": "", "function": "Polyol dehydrogenase that catalyzes the reversible NAD(+)-dependent oxidation of various sugar alcohols. Is active with xylitol, L-iditol and D-sorbitol (D-glucitol) as substrates, leading to the C2-oxidized products D-xylulose, L-sorbose and D-fructose, respectively (By similarity). Is a key enzyme in the polyol pathway that interconverts glucose and fructose via sorbitol, which constitutes an important alternate route for glucose metabolism. May play a role in sperm motility by using sorbitol as an alternative energy source for sperm motility (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0003939 L-iditol 2-dehydrogenase (NAD+) activity;GO:0046526 D-xylulose reductase activity", "go_cellular_component": "GO:0031514 motile cilium;GO:0031966 mitochondrial membrane", "go_biological_process": "GO:0030317 flagellated sperm motility", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q29318-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q29329-1", "uniprot_id": "SMD2_PIG", "mass": 5743.0, "length": 50, "protein_name": "Small nuclear ribonucleoprotein Sm D2", "gene_name": "SNRPD2", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "SNRPD2", "gene_names_refseq": "", "protein_names_uniprotkb": "Small nuclear ribonucleoprotein Sm D2; Sm-D2; snRNP core protein D2", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "8672129", "class_list": "", "function": "Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005685 U1 snRNP;GO:0005634 nucleus;GO:0005829 cytosol;GO:0034709 methylosome;GO:0034715 pICln-Sm protein complex", "go_biological_process": "GO:0000387 spliceosomal snRNP assembly;GO:0000398 mRNA splicing, via spliceosome", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q29329-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q29371-1", "uniprot_id": "TPIS_PIG", "mass": 26730.0, "length": 248, "protein_name": "Triosephosphate isomerase", "gene_name": "TPI1", "organism": "Pig", "refseq_name": "triosephosphate isomerase", "refseq_ac": "NP_001032228", "gene_names_uniprotkb": "TPI1", "gene_names_refseq": "TIM; TPI1", "protein_names_uniprotkb": "Triosephosphate isomerase; 4.2.3.3; 5.3.1.1; Methylglyoxal synthase; TIM; Triose-phosphate isomerase", "protein_names_refseq": "methylglyoxal synthase; triose-phosphate isomerase; triosephosphate isomerase", "tax_id": 9823, "disease": "", "pathway": " (ssc:100157582)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "26711247;8672129", "class_list": "", "function": "It is also responsible for the non-negligible production of methylglyoxal a reactive cytotoxic side-product that modifies and can alter proteins, DNA and lipids., [UniProtKB, UniProtKB]; Sperm TPI content and amounts of GPX5 in seminal plasma may be used as quality markers of boar sperm., [RefSeq, PubMed]; Triosephosphate isomerase is an extremely efficient metabolic enzyme that catalyzes the interconversion between dihydroxyacetone phosphate (DHAP) and D-glyceraldehyde-3-phosphate (G3P) in glycolysis and gluconeogenesis., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q3S2V8", "ec_number_list": "", "go_molecular_function": "GO:0004807 triose-phosphate isomerase activity;GO:0042803 protein homodimerization activity;GO:0008929 methylglyoxal synthase activity", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0019563 glycerol catabolic process;GO:0006094 gluconeogenesis;GO:0006096 glycolytic process;GO:0019242 methylglyoxal biosynthetic process;GO:0046166 glyceraldehyde-3-phosphate biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q29371-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q29412-1", "uniprot_id": "Q29412_PIG", "mass": 21878.0, "length": 186, "protein_name": "Interferon beta 1", "gene_name": "IFNB1", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "IFNB1", "gene_names_refseq": "", "protein_names_uniprotkb": "Interferon beta 1", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-909733); (R-SSC-912694)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005125 cytokine activity;GO:0005132 type I interferon receptor binding;GO:0008811 chloramphenicol O-acetyltransferase activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0002312 B cell activation involved in immune response;GO:0071359 cellular response to dsRNA;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0051607 defense response to virus;GO:0045071 negative regulation of viral genome replication", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q29412-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q29529-1", "uniprot_id": "CBR2_PIG", "mass": 25986.0, "length": 244, "protein_name": "Carbonyl reductase [NADPH] 2", "gene_name": "CBR2", "organism": "Pig", "refseq_name": "carbonyl reductase [NADPH] 2", "refseq_ac": "NP_998992", "gene_names_uniprotkb": "CBR2", "gene_names_refseq": "CBR2", "protein_names_uniprotkb": "Carbonyl reductase [NADPH] 2; 1.1.1.184; LCR; Lung carbonyl reductase; NADPH-dependent carbonyl reductase 2", "protein_names_refseq": "LCR; NADPH-dependent carbonyl reductase 2; carbonyl reductase [NADPH] 2; lung carbonyl reductase", "tax_id": 9823, "disease": "", "pathway": " (ssc:396780)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "1731616;8352790", "class_list": "", "function": "May function in the pulmonary metabolism of endogenous carbonyl compounds, such as aliphatic aldehydes and ketones derived from lipid peroxidation, 3-ketosteroids and fatty aldehydes, as well as in xenobiotic metabolism., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0050038 L-xylulose reductase (NADPH) activity;GO:0004090 carbonyl reductase (NADPH) activity", "go_cellular_component": "GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0005997 xylulose metabolic process;GO:0006006 glucose metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q29529-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q29555-1", "uniprot_id": "GNMT_PIG", "mass": 32893.0, "length": 295, "protein_name": "Glycine N-methyltransferase", "gene_name": "GNMT", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "GNMT", "gene_names_refseq": "", "protein_names_uniprotkb": "Glycine N-methyltransferase; 2.1.1.20", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (ssc:397444)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "8281755", "class_list": "", "function": "Catalyzes the methylation of glycine by using S-adenosylmethionine (AdoMet) to form N-methylglycine (sarcosine) with the concomitant production of S-adenosylhomocysteine (AdoHcy), a reaction regulated by the binding of 5-methyltetrahydrofolate (PubMed:8281755). Plays an important role in the regulation of methyl group metabolism by regulating the ratio between S-adenosyl-L-methionine and S-adenosyl-L-homocysteine (By similarity)., [UniProtKB, UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A5GFQ6", "ec_number_list": "", "go_molecular_function": "GO:0017174 glycine N-methyltransferase activity;GO:0042802 identical protein binding;GO:0005542 folic acid binding;GO:1904047 S-adenosyl-L-methionine binding;GO:0016594 glycine binding", "go_cellular_component": "GO:0005829 cytosol", "go_biological_process": "GO:0051289 protein homotetramerization;GO:0006730 one-carbon metabolic process;GO:0032259 methylation;GO:0046498 S-adenosylhomocysteine metabolic process;GO:0006111 regulation of gluconeogenesis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q29555-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q29558-1", "uniprot_id": "MAOX_PIG", "mass": 62006.0, "length": 557, "protein_name": "NADP-dependent malic enzyme", "gene_name": "ME1", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "ME1", "gene_names_refseq": "", "protein_names_uniprotkb": "NADP-dependent malic enzyme; 1.1.1.40; Malic enzyme 1; NADP-ME", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "8875889", "class_list": "", "function": "Catalyzes the oxidative decarboxylation of (S)-malate in the presence of NADP(+) and divalent metal ions, and decarboxylation of oxaloacetate., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008948 oxaloacetate decarboxylase activity;GO:0000287 magnesium ion binding;GO:0030145 manganese ion binding;GO:0051287 NAD binding;GO:0004470 malic enzyme activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005829 cytosol", "go_biological_process": "GO:0051289 protein homotetramerization;GO:0009725 response to hormone;GO:0006108 malate metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q29558-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q29594-1", "uniprot_id": "KCRB_PIG", "mass": 42657.0, "length": 381, "protein_name": "Creatine kinase B-type", "gene_name": "CKB", "organism": "Pig", "refseq_name": "creatine kinase B-type", "refseq_ac": "NP_001230504", "gene_names_uniprotkb": "CKB", "gene_names_refseq": "B-CK; CKB; CPK-B", "protein_names_uniprotkb": "Creatine kinase B-type; 2.7.3.2; B-CK; CPK-B; Creatine kinase B chain; Creatine phosphokinase M-type", "protein_names_refseq": "Creatine kinase B chain; creatine kinase B-type; creatine kinase, brain; creatine phosphokinase M-type", "tax_id": 9823, "disease": "", "pathway": " (ssc:100627332)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "8672129", "class_list": "", "function": "Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa. Acts as a key regulator of adaptive thermogenesis as part of the futile creatine cycle: localizes to the mitochondria of thermogenic fat cells and acts by mediating phosphorylation of creatine to initiate a futile cycle of creatine phosphorylation and dephosphorylation. During the futile creatine cycle, creatine and N-phosphocreatine are in a futile cycle, which dissipates the high energy charge of N-phosphocreatine as heat without performing any mechanical or chemical work., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004111 creatine kinase activity;GO:0005524 ATP binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005739 mitochondrion;GO:0005829 cytosol;GO:0005886 plasma membrane", "go_biological_process": "GO:0046314 phosphocreatine biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q29594-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q29624-1", "uniprot_id": "CP19A_PIG", "mass": 58227.0, "length": 503, "protein_name": "Aromatase 1", "gene_name": "CYP19A1", "organism": "Pig", "refseq_name": "aromatase 1", "refseq_ac": "NP_999594", "gene_names_uniprotkb": "CYP19A1; CYP19", "gene_names_refseq": "CYP19A1; CYP19", "protein_names_uniprotkb": "Aromatase 1; 1.14.14.14; CYPXIXA1; Cytochrome P-450AROM; Cytochrome P450 19 type I; Estrogen synthase", "protein_names_refseq": "CYPXIXA1; aromatase 1; aromatase cytochrome P450 19A1; cytochrome P-450AROM; cytochrome P450 19 type I; cytochrome P450 aromatase; cytochrome P450, family19, subfamily A, polypeptide 1; estrogen synthase; type III cytochrome p450 aromatase", "tax_id": 9823, "disease": "", "pathway": " (ssc:403331); (R-SSC-193144); (R-SSC-211976)", "pathway_count": 3, "publication_count": 8, "publication_id_list": "17553131;25621494;25628423;29378329;29723543;34933195;8129925;8625924", "class_list": "", "function": "CYP19A1 is an inhibitor of follicular atresia and is regulated by both SMAD4 and miR-10b., [RefSeq, PubMed]; CYP19A1 is involved in sperm fertility and its expression in sperm plays an important role in fertilization., [RefSeq, PubMed]; Catalyzes the formation of aromatic C18 estrogens from C19 androgens., [UniProtKB]; Decreased estradiol production via suppression of aromatase may be one of the mechanisms by which miR-378 regulates the maturation of cumulus-oocyte complexes., [RefSeq, PubMed]; Liver receptor homolog (LRH)-1, not CYP19A1, is a direct functional target of miR-1275., [RefSeq, PubMed]; NR1D1 targeting CYP19A1 inhibits estrogen synthesis in ovarian granulosa cells., [RefSeq, PubMed]; Pig ejaculated spermatozoa express aromatase. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0070330 aromatase activity;GO:0005506 iron ion binding;GO:0020037 heme binding", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0016020 membrane", "go_biological_process": "GO:0032355 response to estradiol;GO:0006694 steroid biosynthetic process;GO:0008209 androgen metabolic process;GO:0008585 female gonad development", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q29624-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2EN75-1", "uniprot_id": "S10A6_PIG", "mass": 10060.0, "length": 90, "protein_name": "Protein S100-A6", "gene_name": "S100A6", "organism": "Pig", "refseq_name": "protein S100-A6", "refseq_ac": "NP_001038022", "gene_names_uniprotkb": "S100A6", "gene_names_refseq": "S100A6", "protein_names_uniprotkb": "Protein S100-A6; Calcyclin; S100 calcium-binding protein A6", "protein_names_refseq": "calcyclin; protein S100-A6", "tax_id": 9823, "disease": "", "pathway": " (ssc:733608)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "25480733", "class_list": "", "function": "May function as calcium sensor and modulator, contributing to cellular calcium signaling. May function by interacting with other proteins, such as TPR-containing proteins, and indirectly play a role in many physiological processes such as the reorganization of the actin cytoskeleton and in cell motility. Binds 2 calcium ions. Calcium binding is cooperative (By similarity)., [UniProtKB]; S100A6 is upregulated during PRRSV infection; there is a putative NF-kappaB binding site in the core promoter region, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0048306 calcium-dependent protein binding;GO:0005509 calcium ion binding;GO:0044548 S100 protein binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005635 nuclear envelope;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "GO:0098586 cellular response to virus", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q2EN75-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2HXW4-1", "uniprot_id": "NET1_PIG", "mass": 67372.0, "length": 600, "protein_name": "Netrin-1", "gene_name": "NTN1", "organism": "Pig", "refseq_name": "netrin-1 precursor", "refseq_ac": "NP_001038013", "gene_names_uniprotkb": "NTN1", "gene_names_refseq": "NTN1; UNC-6", "protein_names_uniprotkb": "Netrin-1", "protein_names_refseq": "netrin-1 precursor", "tax_id": 9823, "disease": "", "pathway": " (ssc:733599)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "18497489;20696210;20969752", "class_list": "", "function": "Findings show that the netrin-1 and p53RDL1 system may regulate the induction of apoptosis in porcine granulosa cells, [RefSeq, PubMed]; Netrin-1 could be important for follicular function in the swine., [RefSeq, PubMed]; Netrins control guidance of CNS commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively. Binding to UNC5C might cause dissociation of UNC5C from polymerized TUBB3 in microtubules and thereby lead to increased microtubule dynamics and axon repulsion (By similarity). Involved in dorsal root ganglion axon projection towards the spinal cord (By similarity). It also serves as a survival factor via its association with its receptors which prevent the initiation of apoptosis. Involved in colorectal tumorigenesis by regulating apoptosis (By similarity)., [UniProtKB, UniProtKB, UniProtKB]; Treatment with endogenous anti-inflammatory protein netrin-1 reduces pulmonary inflammation during the initial stages of acute lung injury., [RefSeq, PubMed]", "predicted_glycosites": 4, "predicted_n_glycosites": 4, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005576 extracellular region;GO:0005737 cytoplasm;GO:0005604 basement membrane", "go_biological_process": "GO:0016358 dendrite development;GO:0006915 apoptotic process;GO:0007265 Ras protein signal transduction;GO:0009887 animal organ morphogenesis;GO:0045773 positive regulation of axon extension", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q2HXW4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2IA00-1", "uniprot_id": "SPEF2_PIG", "mass": 208804.0, "length": 1812, "protein_name": "Sperm flagella and cilia-associated protein 2", "gene_name": "SPEF2", "organism": "Pig", "refseq_name": "sperm flagellar protein 2", "refseq_ac": "NP_001038026", "gene_names_uniprotkb": "SPEF2; KPL2", "gene_names_refseq": "KPL2; SPEF2", "protein_names_uniprotkb": "Sperm flagella and cilia-associated protein 2; Protein KPL2; Sperm flagellar protein 2", "protein_names_refseq": "KPL2-like protein; sperm flagellar 2; sperm flagellar protein 2", "tax_id": 9823, "disease": "", "pathway": " (ssc:733620)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "16549801;17610085;19889948;24712415", "class_list": "", "function": "Integration of a transposition-competent L1 element into KPL2 is responsible for the defective spermatozoa and infertility., [RefSeq, PubMed]; KPL2 gene is important for correct axoneme development and provide insight into abnormal sperm development and infertility disorders, [RefSeq, PubMed]; PRLR was identified as down-regulated in the oviduct of immotile short tail sperm (ISTS) homozygous sows. The methylation pattern of the PRLR gene region appeared unaffected., [RefSeq, PubMed]; Required for correct axoneme development in spermatozoa (PubMed:16549801, PubMed:19889948). Important for normal development of the manchette and sperm head morphology. Essential for male fertility. Plays a role in localization of the intraflagellar transport protein IFT20 to the manchette, suggesting function as an adapter for dynein-mediated protein transport during spermatogenesis. Plays a role in bone growth where it seems to be required for normal osteoblast differentiation (By similarity). Required for normal beat frequency of tracheal epithelial cilia and oviduct cilia., [UniProtKB, UniProtKB, PubMed, PubMed, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "Q288C5", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0036126 sperm flagellum;GO:0002177 manchette;GO:0097225 sperm midpiece", "go_biological_process": "GO:0007288 sperm axoneme assembly", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q2IA00-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2MJK3-1", "uniprot_id": "RASN_PIG", "mass": 21229.0, "length": 189, "protein_name": "GTPase NRas", "gene_name": "NRAS", "organism": "Pig", "refseq_name": "GTPase NRas", "refseq_ac": "NP_001038002", "gene_names_uniprotkb": "NRAS", "gene_names_refseq": "H-RAS; HRAS; NRAS", "protein_names_uniprotkb": "GTPase NRas; 3.6.5.2; Transforming protein N-Ras", "protein_names_refseq": "GTPase NRas; neuroblastoma RAS viral (v-ras) oncogene homolog; neuroblastoma RAS viral oncogene homolog; neuroblastoma ras oncogene; transforming protein N-Ras; v-Ha-ras Harvey rat sarcoma viral oncogene homolog", "tax_id": 9823, "disease": "", "pathway": " (ssc:100739349); (R-SSC-1169092); (R-SSC-1250347); (R-SSC-1433557); (R-SSC-171007); (R-SSC-179812); (R-SSC-180336); (R-SSC-186763); (R-SSC-1963640); (R-SSC-210993); (R-SSC-2179392); (R-SSC-2424491); (R-SSC-2871796); (R-SSC-375165); (R-SSC-5218921); (R-SSC-5654688); (R-SSC-5654693); (R-SSC-5654699); (R-SSC-5654700); (R-SSC-5654704); (R-SSC-5654706); (R-SSC-5654712); (R-SSC-5654719); (R-SSC-5658442); (R-SSC-5673000); (R-SSC-5673001); (R-SSC-5674135); (R-SSC-5675221); (R-SSC-6798695); (R-SSC-8849471); (R-SSC-8851805); (R-SSC-9607240); (R-SSC-9634635); (R-SSC-9648002)", "pathway_count": 34, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Signal transducer in the Ras-MAPK signaling pathway that regulates cell proliferation and survival (By similarity). Ras proteins bind GDP/GTP and possess intrinsic GTPase activity (By similarity). Recognized by LZTR1 that mediates its ubiquitination by a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0044877 protein-containing complex binding;GO:0003925 G protein activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005886 plasma membrane", "go_biological_process": "GO:0008284 positive regulation of cell population proliferation;GO:0007265 Ras protein signal transduction;GO:0001938 positive regulation of endothelial cell proliferation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2MJK3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2MJV8-1", "uniprot_id": "PALM_PIG", "mass": 42380.0, "length": 387, "protein_name": "Paralemmin-1", "gene_name": "PALM", "organism": "Pig", "refseq_name": "paralemmin-1", "refseq_ac": "NP_001033725", "gene_names_uniprotkb": "PALM", "gene_names_refseq": "PALM", "protein_names_uniprotkb": "Paralemmin-1; Paralemmin", "protein_names_refseq": "paralemmin-1", "tax_id": 9823, "disease": "", "pathway": " (ssc:654410)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Involved in plasma membrane dynamics and cell process formation. Necessary for axonal and dendritic filopodia induction, for dendritic spine maturation and synapse formation in a palmitoylation-dependent manner (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 8, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0016323 basolateral plasma membrane;GO:0030424 axon;GO:0043197 dendritic spine;GO:0098794 postsynapse;GO:0030175 filopodium", "go_biological_process": "GO:0007193 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway;GO:0008360 regulation of cell shape;GO:0051491 positive regulation of filopodium assembly;GO:0060074 synapse maturation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q2MJV8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2TNK5-1", "uniprot_id": "ANGL4_PIG", "mass": 45534.0, "length": 412, "protein_name": "Angiopoietin-related protein 4", "gene_name": "ANGPTL4", "organism": "Pig", "refseq_name": "angiopoietin-related protein 4 precursor", "refseq_ac": "NP_001033733", "gene_names_uniprotkb": "ANGPTL4; PGAR", "gene_names_refseq": "ANGPTL4; PGAR", "protein_names_uniprotkb": "Angiopoietin-related protein 4; Angiopoietin-like protein 4", "protein_names_refseq": "Angiopoietin-related protein 4; PPARG angiopoietin-related protein; angiopoietin-like protein 4; angiopoietin-related protein 4 precursor", "tax_id": 9823, "disease": "", "pathway": " (ssc:397628); (R-SSC-8963889); (R-SSC-9762292)", "pathway_count": 3, "publication_count": 2, "publication_id_list": "24782129;38424378", "class_list": "", "function": "Knockdown of ANGPTL4 inhibits adipogenesis of preadipocyte via autophagy., [RefSeq, PubMed]; Mediates inactivation of the lipoprotein lipase LPL, and thereby plays a role in the regulation of triglyceride clearance from the blood serum and in lipid metabolism. May also play a role in regulating glucose homeostasis and insulin sensitivity. Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage (By similarity). Upon heterologous expression, inhibits the adhesion of endothelial cell to the extracellular matrix (ECM), and inhibits the reorganization of the actin cytoskeleton, formation of actin stress fibers and focal adhesions in endothelial cells that have adhered to ANGPTL4-containing ECM (in vitro) (By similarity). Depending on context, may modulate tumor-related angiogenesis (By similarity)., [UniProtKB, UniProtKB, UniProtKB]; Mediates inactivation of the lipoprotein lipase LPL, and thereby plays an important role in the regulation of triglyceride clearance from the blood serum and in lipid metabolism. Has higher activity in LPL inactivation than the uncleaved protein., [UniProtKB, UniProtKB]; The ANGPTL4 G/A polymerase chain reaction-single strand conformation polymorphism (PCR-SSCP) showed a significant effect on intramuscular fat Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 1, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "Q1H5H6;Q7YS01", "ec_number_list": "", "go_molecular_function": "GO:0004857 enzyme inhibitor activity;GO:0042802 identical protein binding;GO:0055102 lipase inhibitor activity;GO:0035473 lipase binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0031012 extracellular matrix", "go_biological_process": "GO:0043335 protein unfolding;GO:0001525 angiogenesis;GO:0006629 lipid metabolic process;GO:0043066 negative regulation of apoptotic process;GO:0045717 negative regulation of fatty acid biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q2TNK5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q2XSV9-1", "uniprot_id": "GNA11_PIG", "mass": 42064.0, "length": 359, "protein_name": "Guanine nucleotide-binding protein subunit alpha-11", "gene_name": "GNA11", "organism": "Pig", "refseq_name": "guanine nucleotide-binding protein subunit alpha-11", "refseq_ac": "NP_001038003", "gene_names_uniprotkb": "GNA11", "gene_names_refseq": "GNA11", "protein_names_uniprotkb": "Guanine nucleotide-binding protein subunit alpha-11; G alpha-11; G protein subunit alpha-11", "protein_names_refseq": "g alpha-11; guanine nucleotide binding protein (G protein), alpha 11 (Gq class); guanine nucleotide binding protein alpha 11; guanine nucleotide-binding protein subunit alpha-11", "tax_id": 9823, "disease": "", "pathway": " (ssc:733588)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "18330691", "class_list": "", "function": "Guanine nucleotide-binding proteins (G proteins) function as transducers downstream of G protein-coupled receptors (GPCRs) in numerous signaling cascades. The alpha chain contains the guanine nucleotide binding site and alternates between an active, GTP-bound state and an inactive, GDP-bound state. Signaling by an activated GPCR promotes GDP release and GTP binding. The alpha subunit has a low GTPase activity that converts bound GTP to GDP, thereby terminating the signal. Both GDP release and GTP hydrolysis are modulated by numerous regulatory proteins. Signaling is mediated via phospholipase C-beta-dependent inositol lipid hydrolysis for signal propagation: activates phospholipase C-beta: following GPCR activation, GNA11 activates PLC-beta (PLCB1, PLCB2, PLCB3 or PLCB4), leading to production of diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Transduces FFAR4 signaling in response to long-chain fatty acids (LCFAs) (By similarity). Together with GNAQ, required for heart development (By similarity). In the respiratory epithelium, transmits OXGR1-dependent signals that lead to downstream intracellular Ca(2+) release and mucocilliary clearance of airborne pathogens., [UniProtKB, UniProtKB, UniProtKB]; The phylogenetic trees reveal that porcine Gna11, is evolutionarily close to the human homolog., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0046872 metal ion binding;GO:0001664 G protein-coupled receptor binding;GO:0031683 G-protein beta/gamma-subunit complex binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0016020 membrane;GO:0045202 synapse;GO:0001750 photoreceptor outer segment;GO:0005834 heterotrimeric G-protein complex", "go_biological_process": "GO:0060158 phospholipase C-activating dopamine receptor signaling pathway;GO:0007213 G protein-coupled acetylcholine receptor signaling pathway;GO:0001508 action potential;GO:0007188 adenylate cyclase-modulating G protein-coupled receptor signaling pathway;GO:0007603 phototransduction, visible light", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q2XSV9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3BDI7-1", "uniprot_id": "DSG1_PIG", "mass": 113318.0, "length": 1045, "protein_name": "Desmoglein-1", "gene_name": "DSG1", "organism": "Pig", "refseq_name": "desmoglein-1 precursor", "refseq_ac": "NP_001030612", "gene_names_uniprotkb": "DSG1", "gene_names_refseq": "DSG1", "protein_names_uniprotkb": "Desmoglein-1; DG1; DGI; Desmosomal glycoprotein 1", "protein_names_refseq": "DG1; DGI; desmoglein-1 precursor; desmosomal glycoprotein 1", "tax_id": 9823, "disease": "", "pathway": " (ssc:641355); (R-SSC-351906); (R-SSC-6798695); (R-SSC-6805567); (R-SSC-6809371); (R-SSC-9696264); (R-SSC-9696270)", "pathway_count": 7, "publication_count": 2, "publication_id_list": "16238811;17397555", "class_list": "", "function": "A component of desmosome cell-cell junctions which are required for positive regulation of cellular adhesion (By similarity). Promotes differentiation of keratinocytes via interaction with ERBIN (By similarity). Reduces activation of RAS/ERK signaling pathways in keratinocytes via promoting ERBIN localization to the cell membrane and its interaction with SHOC2, this competitively reduces the formation of RAS-SHOC2 ERK-activating complexes (By similarity). Mediates the interaction between the desmosome and COP9 signalosome complex (CSN) protein complex (By similarity). As a result of this interaction, promotes keratinocyte differentiation via deneddylation of EGFR resulting in a reduction in EGFR protein stabilization and translocation away from the cell membrane (By similarity). Critical for epidermal integrity and barrier function of the skin (By similarity). Required for esophageal epithelial barrier integrity and correct intercellular spacing in differentiated esophageal epithelium (By similarity). Required for recovery of epidermal architecture and correct expression of differentiation markers following UVB exposure (By similarity). May also be required for OCLN involvement in tight junctions (By similarity)., [UniProtKB, UniProtKB, UniProtKB]; The study indicated a possible correlation between the genotypes of two out of seven SNPs found in the porcine desmoglein 1 gene and the susceptibility to exudative epidermitis. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 5, "predicted_n_glycosites": 3, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005509 calcium ion binding;GO:0045295 gamma-catenin binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0030057 desmosome", "go_biological_process": "GO:0098609 cell-cell adhesion;GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q3BDI7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3I5G7-1", "uniprot_id": "SYUA_PIG", "mass": 14520.0, "length": 140, "protein_name": "Alpha-synuclein", "gene_name": "SNCA", "organism": "Pig", "refseq_name": "alpha-synuclein", "refseq_ac": "NP_001032222", "gene_names_uniprotkb": "SNCA", "gene_names_refseq": "SNCA", "protein_names_uniprotkb": "Alpha-synuclein", "protein_names_refseq": "alpha-synuclein", "tax_id": 9823, "disease": "", "pathway": " (ssc:641350); (R-SSC-9833482)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "30067901;33152422", "class_list": "", "function": "Animal alpha-synucleins (aSNs) share three substitutions compared to human aSN: A53T, G68E, and V95G, [RefSeq, PubMed]; Molecular characteristics of porcine alpha-synuclein splicing variants., [RefSeq, PubMed]; Neuronal protein that plays several roles in synaptic activity such as regulation of synaptic vesicle trafficking and subsequent neurotransmitter release (By similarity). Participates as a monomer in synaptic vesicle exocytosis by enhancing vesicle priming, fusion and dilation of exocytotic fusion pores (By similarity). Mechanistically, acts by increasing local Ca(2+) release from microdomains which is essential for the enhancement of ATP-induced exocytosis (By similarity). Also acts as a molecular chaperone in its multimeric membrane-bound state, assisting in the folding of synaptic fusion components called SNAREs (Soluble NSF Attachment Protein REceptors) at presynaptic plasma membrane in conjunction with cysteine string protein-alpha/DNAJC5 (By similarity). This chaperone activity is important to sustain normal SNARE-complex assembly during aging (By similarity). Also plays a role in the regulation of the dopamine neurotransmission by associating with the dopamine transporter (DAT1) and thereby modulating its activity (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0042802 identical protein binding;GO:0005507 copper ion binding;GO:1903136 cuprous ion binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0016020 membrane", "go_biological_process": "GO:0050808 synapse organization;GO:0001963 synaptic transmission, dopaminergic;GO:0014059 regulation of dopamine secretion;GO:0016082 synaptic vesicle priming;GO:0048488 synaptic vesicle endocytosis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q3I5G7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q3S853-1", "uniprot_id": "RGS2_PIG", "mass": 24390.0, "length": 212, "protein_name": "Regulator of G protein signaling 2", "gene_name": "RGS2", "organism": "Pig", "refseq_name": "regulator of G-protein signaling 2", "refseq_ac": "NP_001038065", "gene_names_uniprotkb": "RGS2", "gene_names_refseq": "RGS2", "protein_names_uniprotkb": "Regulator of G protein signaling 2; RGS2", "protein_names_refseq": "regulator of G-protein signaling 2, 24kDa; regulator of G-protein signaling 2; regulator of G-protein signalling 2, 24kDa", "tax_id": 9823, "disease": "", "pathway": " (ssc:733670); (R-SSC-416476)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form (By similarity). It is involved in the negative regulation of the angiotensin-activated signaling pathway (By similarity). Plays a role in the regulation of blood pressure in response to signaling via G protein-coupled receptors and GNAQ. Plays a role in regulating the constriction and relaxation of vascular smooth muscle (By similarity). Binds EIF2B5 and blocks its activity, thereby inhibiting the translation of mRNA into protein (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q2V8V0", "ec_number_list": "", "go_molecular_function": "GO:0005096 GTPase activator activity;GO:0001965 G-protein alpha-subunit binding;GO:0010855 adenylate cyclase inhibitor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005886 plasma membrane", "go_biological_process": "GO:0071877 regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway;GO:0006417 regulation of translation;GO:0007283 spermatogenesis;GO:0045744 negative regulation of G protein-coupled receptor signaling pathway;GO:0060087 relaxation of vascular associated smooth muscle", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q3S853-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q4A3R3-1", "uniprot_id": "DMBT1_PIG", "mass": 132225.0, "length": 1204, "protein_name": "Scavenger receptor cysteine-rich domain-containing protein DMBT1", "gene_name": "DMBT1", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "DMBT1", "gene_names_refseq": "", "protein_names_uniprotkb": "Scavenger receptor cysteine-rich domain-containing protein DMBT1; Deleted in malignant brain tumors 1 protein; Hensin", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (ssc:751862)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "15922517;16624504", "class_list": "", "function": "May play roles in mucosal defense system and cellular immune defense. May play a role in liver regeneration. May be an important factor in fate decision and differentiation of transit-amplifying ductular (oval) cells within the hepatic lineage. May function as a binding protein in saliva for the regulation of taste sensation. May play a role as an opsonin receptor for SFTPD and SPAR in macrophage tissues throughout the body, including epithelial cells lining the gastrointestinal tract. Required for terminal differentiation of columnar epithelial cells during early embryogenesis. Displays a broad calcium-dependent binding spectrum against both Gram-positive and Gram-negative bacteria, suggesting a role in defense against bacterial pathogens. Binds to a range of poly-sulfated and poly-phosphorylated ligands which may explain its broad bacterial-binding specificity. Inhibits cytoinvasion of S.enterica. Associates with the actin cytoskeleton and is involved in its remodeling during regulated exocytosis. Interacts with pancreatic zymogens in a pH-dependent manner and may act as a Golgi cargo receptor in the regulated secretory pathway of the pancreatic acinar cell (By similarity)., [UniProtKB]", "predicted_glycosites": 8, "predicted_n_glycosites": 8, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 8, "binding_glycan_count": 0, "secondary_ac_list": "Q0W9P8;Q95316", "ec_number_list": "", "go_molecular_function": "GO:0035375 zymogen binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0005886 plasma membrane;GO:0031012 extracellular matrix;GO:0030658 transport vesicle membrane;GO:0042589 zymogen granule membrane", "go_biological_process": "GO:0015031 protein transport;GO:0030154 cell differentiation;GO:0050829 defense response to Gram-negative bacterium;GO:0050830 defense response to Gram-positive bacterium", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q4A3R3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q4G1G8-1", "uniprot_id": "CH25H_PIG", "mass": 31482.0, "length": 270, "protein_name": "Cholesterol 25-hydroxylase", "gene_name": "CH25H", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "CH25H", "gene_names_refseq": "", "protein_names_uniprotkb": "Cholesterol 25-hydroxylase; 1.14.99.38; Cholesterol 25-monooxygenase", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalyzes the formation of 25-hydroxycholesterol from cholesterol, leading to repress cholesterol biosynthetic enzymes (By similarity). Plays a key role in cell positioning and movement in lymphoid tissues: 25-hydroxycholesterol is an intermediate in biosynthesis of 7-alpha,25-dihydroxycholesterol (7-alpha,25-OHC), an oxysterol that acts as a ligand for the G protein-coupled receptor GPR183/EBI2, a chemotactic receptor for a number of lymphoid cells (By similarity). May play an important role in regulating lipid metabolism by synthesizing a corepressor that blocks sterol regulatory element binding protein (SREBP) processing. As an interferon-stimulated gene, has broad antiviral activities against a wide range of enveloped viruses. Its product, 25-hydroxycholesterol, activates the ER-localized enzyme ACAT to induce internalization of accessible cholesterol on the plasma membrane and restricts virus-host membranes fusion which inhibits virus replication (By similarity). In testis, production of 25-hydroxycholesterol by macrophages plays a role in Leydig cell differentiation (By similarity). Required to restrain inflammation in macrophages: production of 25-hydroxycholesterol protects macrophages from cholesterol overload, thereby preventing mitochondrial DNA release and subsequent activation of the AIM2 inflammasome (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0000254 C-4 methylsterol oxidase activity;GO:0005506 iron ion binding;GO:0008395 steroid hydroxylase activity;GO:0001567 cholesterol 25-hydroxylase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0008203 cholesterol metabolic process;GO:0016126 sterol biosynthetic process;GO:0035754 B cell chemotaxis;GO:0034340 response to type I interferon;GO:1903914 negative regulation of fusion of virus membrane with host plasma membrane", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q4G1G8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q4LE88-1", "uniprot_id": "S45A2_PIG", "mass": 58461.0, "length": 532, "protein_name": "Membrane-associated transporter protein", "gene_name": "SLC45A2", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "SLC45A2; MATP", "gene_names_refseq": "", "protein_names_uniprotkb": "Membrane-associated transporter protein; Solute carrier family 45 member 2", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "16441305", "class_list": "", "function": "Proton-associated glucose and sucrose transporter. May be able to transport also fructose. Expressed at a late melanosome maturation stage where functions as a proton/glucose exporter which increase lumenal pH by decreasing glycolysis. Regulates melanogenesis by maintaining melanosome neutralization that is initially initiated by transient OCA2 and required for a proper function of the tyrosinase TYR., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 1, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008506 sucrose:proton symporter activity;GO:0005356 D-glucose:proton symporter activity", "go_cellular_component": "GO:0033162 melanosome membrane", "go_biological_process": "GO:0007601 visual perception;GO:0048066 developmental pigmentation;GO:0035752 lysosomal lumen pH elevation;GO:0015770 sucrose transport;GO:0006583 melanin biosynthetic process from tyrosine", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q4LE88-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q4PJW2-1", "uniprot_id": "NCOA1_PIG", "mass": 156925.0, "length": 1440, "protein_name": "Nuclear receptor coactivator 1", "gene_name": "NCOA1", "organism": "Pig", "refseq_name": "nuclear receptor coactivator 1", "refseq_ac": "NP_001020399", "gene_names_uniprotkb": "NCOA1; SRC1", "gene_names_refseq": "NCOA1; SRC1", "protein_names_uniprotkb": "Nuclear receptor coactivator 1; 2.3.1.48; NCoA-1; SRC-1; Steroid receptor coactivator 1", "protein_names_refseq": "NCoA-1; SRC-1; nuclear receptor coactivator 1; steroid receptor coactivator 1", "tax_id": 9823, "disease": "", "pathway": " (ssc:574068)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "16753821", "class_list": "", "function": "Nuclear receptor coactivator that directly binds nuclear receptors and stimulates the transcriptional activities in a hormone-dependent fashion. Involved in the coactivation of different nuclear receptors, such as for steroids (PGR, GR and ER), retinoids (RXRs), thyroid hormone (TRs) and prostanoids (PPARs). Also involved in coactivation mediated by STAT3, STAT5A, STAT5B and STAT6 transcription factors. Displays histone acetyltransferase activity toward H3 and H4; the relevance of such activity remains however unclear. Plays a central role in creating multisubunit coactivator complexes that act via remodeling of chromatin, and possibly acts by participating in both chromatin remodeling and recruitment of general transcription factors. Required with NCOA2 to control energy balance between white and brown adipose tissues. Required for mediating steroid hormone response (By similarity)., [UniProtKB]; We cloned and sequenced full length cDNA of NCOA-1 gene in pig. The putative protein includes 1440 amino acids. Sequences alignment showed that pig NCOA-1 gene cDNA sequence has identity of 93.73% with human and mouse., [RefSeq, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 11, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0061733 protein-lysine-acetyltransferase activity;GO:0003713 transcription coactivator activity;GO:0046983 protein dimerization activity;GO:0016922 nuclear receptor binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005667 transcription regulator complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0032870 cellular response to hormone stimulus;GO:0045893 positive regulation of DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q4PJW2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q4PR21-1", "uniprot_id": "CCL25_PIG", "mass": 16878.0, "length": 151, "protein_name": "C-C motif chemokine 25", "gene_name": "CCL25", "organism": "Pig", "refseq_name": "C-C motif chemokine 25 precursor", "refseq_ac": "NP_001020385", "gene_names_uniprotkb": "CCL25", "gene_names_refseq": "CCL25", "protein_names_uniprotkb": "C-C motif chemokine 25; Chemokine ligand 25; Small-inducible cytokine A25", "protein_names_refseq": "C-C motif chemokine 25 precursor; C-C motif chemokine 25; chemokine (C-C motif) ligand 25; chemokine ligand 25; small-inducible cytokine A25", "tax_id": 9823, "disease": "", "pathway": " (ssc:448799); (R-SSC-380108); (R-SSC-418594)", "pathway_count": 3, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Potentially involved in T-cell development. Recombinant protein shows chemotactic activity on thymocytes, macrophages, THP-1 cells, and dendritics cells but is inactive on peripheral blood lymphocytes and neutrophils. Binds to CCR9. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4 (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008009 chemokine activity;GO:0031735 CCR10 chemokine receptor binding;GO:0042379 chemokine receptor binding;GO:0048020 CCR chemokine receptor binding", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0006954 inflammatory response;GO:0030335 positive regulation of cell migration;GO:0061844 antimicrobial humoral immune response mediated by antimicrobial peptide;GO:0070098 chemokine-mediated signaling pathway;GO:0001954 positive regulation of cell-matrix adhesion", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q4PR21-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q52N47-1", "uniprot_id": "ITM2B_PIG", "mass": 30284.0, "length": 266, "protein_name": "Integral membrane protein 2B", "gene_name": "ITM2B", "organism": "Pig", "refseq_name": "integral membrane protein 2B", "refseq_ac": "NP_001035834", "gene_names_uniprotkb": "ITM2B", "gene_names_refseq": "Bri; ITM2B; imBRI2", "protein_names_uniprotkb": "Integral membrane protein 2B; ABri23; Bri; C-terminal peptide; Immature BRI2; Mature BRI2; P23 peptide; Transmembrane protein BRI; imBRI2; mBRI2", "protein_names_refseq": "BRICHOS-like protein; immature BRI2; integral membrane protein 2B; transmembrane protein BRI", "tax_id": 9823, "disease": "", "pathway": " (ssc:595120)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Bri23 peptide prevents aggregation of APP amyloid-beta protein 42 into toxic oligomers., [UniProtKB]; Mature BRI2 (mBRI2) functions as a modulator of the amyloid-beta A4 precursor protein (APP) processing leading to a strong reduction in the secretion of secretase-processed amyloid-beta protein 40 and amyloid-beta protein 42., [UniProtKB]; Plays a regulatory role in the processing of the amyloid-beta A4 precursor protein (APP) and acts as an inhibitor of the amyloid-beta peptide aggregation and fibrils deposition. Plays a role in the induction of neurite outgrowth. Functions as a protease inhibitor by blocking access of secretases to APP cleavage sites (By similarity)., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0001540 amyloid-beta binding", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005615 extracellular space;GO:0005794 Golgi apparatus;GO:0005886 plasma membrane;GO:0010008 endosome membrane", "go_biological_process": "GO:0042985 negative regulation of amyloid precursor protein biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q52N47-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q52NJ6-1", "uniprot_id": "RAB14_PIG", "mass": 23927.0, "length": 215, "protein_name": "Ras-related protein Rab-14", "gene_name": "RAB14", "organism": "Pig", "refseq_name": "ras-related protein Rab-14", "refseq_ac": "NP_001026953", "gene_names_uniprotkb": "RAB14", "gene_names_refseq": "RAB14", "protein_names_uniprotkb": "Ras-related protein Rab-14; 3.6.5.2", "protein_names_refseq": "ras-related protein Rab-14", "tax_id": 9823, "disease": "", "pathway": " (ssc:595112)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "17380425", "class_list": "", "function": "The complete coding sequences of three porcine genes--RAB14, S35A3 and ITM2A were amplified and nucleotide sequence and tissue expression were analysed., [RefSeq, PubMed]; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion (By similarity). RAB14 is involved in membrane trafficking between the Golgi complex and endosomes during early embryonic development (By similarity). Regulates the Golgi to endosome transport of FGFR-containing vesicles during early development, a key process for developing basement membrane and epiblast and primitive endoderm lineages during early postimplantation development. May act by modulating the kinesin KIF16B-cargo association to endosomes (By similarity). Regulates, together with its guanine nucleotide exchange factor DENND6A, the specific endocytic transport of ADAM10, N-cadherin/CDH2 shedding and cell-cell adhesion. Mediates endosomal tethering and fusion through the interaction with RUFY1 and RAB4B (By similarity). Interaction with RAB11FIP1 may function in the process of neurite formation (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0046872 metal ion binding;GO:0019003 GDP binding;GO:0003925 G protein activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0005769 early endosome;GO:0005829 cytosol;GO:0055037 recycling endosome;GO:0012505 endomembrane system", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0032880 regulation of protein localization;GO:0042742 defense response to bacterium;GO:0006895 Golgi to endosome transport;GO:0032456 endocytic recycling", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q52NJ6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q5BLZ2-1", "uniprot_id": "PLIN3_PIG", "mass": 47900.0, "length": 439, "protein_name": "Perilipin-3", "gene_name": "PLIN3", "organism": "Pig", "refseq_name": "perilipin-3", "refseq_ac": "NP_001026948", "gene_names_uniprotkb": "PLIN3; M6PRBP1; TIP47", "gene_names_refseq": "M6PRBP1; PLIN3", "protein_names_uniprotkb": "Perilipin-3; Cargo selection protein TIP47; Mannose-6-phosphate receptor-binding protein 1", "protein_names_refseq": "47 kDa tail interaction protein; TIP47; cargo selection protein TIP47; mannose-6-phosphate receptor binding protein 1; perilipin-3", "tax_id": 9823, "disease": "", "pathway": " (ssc:595103)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "18298936;29233207", "class_list": "", "function": "PLIN3 expression in cumulus cells and oocytes during in vitro maturation., [RefSeq, PubMed]; Structural component of lipid droplets, which is required for the formation and maintenance of lipid storage droplets. Required for the transport of mannose 6-phosphate receptors (MPR) from endosomes to the trans-Golgi network., [UniProtKB, UniProtKB]; This work describes the cloning and sequencing of porcine PLIN and M6PRBP1 cDNAs, the chromosome mapping of these two genes, as well as the expression pattern of porcine PAT genes., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 9, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005811 lipid droplet;GO:0005829 cytosol;GO:0010008 endosome membrane", "go_biological_process": "GO:0042149 cellular response to glucose starvation;GO:0010890 positive regulation of triglyceride storage;GO:0019915 lipid storage;GO:1905691 lipid droplet disassembly", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q5BLZ2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q5FZP5-1", "uniprot_id": "SCG2_PIG", "mass": 70999.0, "length": 616, "protein_name": "Secretogranin-2", "gene_name": "SCG2", "organism": "Pig", "refseq_name": "secretogranin-2 precursor", "refseq_ac": "NP_001012299", "gene_names_uniprotkb": "SCG2", "gene_names_refseq": "SCG2; SCGG2; SgII", "protein_names_uniprotkb": "Secretogranin-2; Secretogranin II; SgII", "protein_names_refseq": "Secretogranin-2; chromogranin C; secretogranin-2 precursor", "tax_id": 9823, "disease": "", "pathway": " (ssc:497237)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "18278550", "class_list": "", "function": "Comparative sequencing and EST analysis revealed nine SNPs in porcine SCG2 cDNA, including seven SNPs in the coding region and two SNPs in the 3' UTR., [RefSeq, PubMed]; Neuroendocrine protein of the granin family that regulates the biogenesis of secretory granules., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 6, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0042056 chemoattractant activity;GO:0005125 cytokine activity", "go_cellular_component": "GO:0005615 extracellular space;GO:0030141 secretory granule", "go_biological_process": "GO:0001525 angiogenesis;GO:0048245 eosinophil chemotaxis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q5FZP5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q5PXD3-1", "uniprot_id": "CD3G_PIG", "mass": 20461.0, "length": 182, "protein_name": "T-cell surface glycoprotein CD3 gamma chain", "gene_name": "CD3G", "organism": "Pig", "refseq_name": "T-cell surface glycoprotein CD3 gamma chain precursor", "refseq_ac": "NP_001008686", "gene_names_uniprotkb": "CD3G", "gene_names_refseq": "CD3G", "protein_names_uniprotkb": "T-cell surface glycoprotein CD3 gamma chain; T-cell receptor T3 gamma chain", "protein_names_refseq": "CD3 antigen gamma chain; CD3g molecule; T-cell receptor T3 gamma chain; T-cell surface glycoprotein CD3 gamma chain precursor; T-cell surface glycoprotein CD3 gamma chain", "tax_id": 9823, "disease": "", "pathway": " (ssc:494013); (R-SSC-198933); (R-SSC-202424); (R-SSC-202427); (R-SSC-202430); (R-SSC-202433); (R-SSC-2029481); (R-SSC-2029482); (R-SSC-2029485); (R-SSC-389948); (R-SSC-8856825); (R-SSC-8856828)", "pathway_count": 12, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD247/CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of downstream signaling pathways. In addition to this role of signal transduction in T-cell activation, CD3G plays an essential role in the dynamic regulation of TCR expression at the cell surface. Indeed, constitutive TCR cycling is dependent on the di-leucine-based (diL) receptor-sorting motif present in CD3G., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004888 transmembrane signaling receptor activity", "go_cellular_component": "GO:0009897 external side of plasma membrane;GO:0042105 alpha-beta T cell receptor complex", "go_biological_process": "GO:0007166 cell surface receptor signaling pathway;GO:0002250 adaptive immune response;GO:0045059 positive thymic T cell selection", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q5PXD3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q5S1U1-1", "uniprot_id": "HSPB1_PIG", "mass": 22942.0, "length": 207, "protein_name": "Heat shock protein beta-1", "gene_name": "HSPB1", "organism": "Pig", "refseq_name": "heat shock protein beta-1", "refseq_ac": "NP_001007519", "gene_names_uniprotkb": "HSPB1; HSP27", "gene_names_refseq": "HSP27; HSPB1", "protein_names_uniprotkb": "Heat shock protein beta-1; HSP 27; Heat shock 27 kDa protein; HspB1", "protein_names_refseq": "27 kDa heat shock protein 1; HSP 27; heat shock 27 kDa protein; heat shock 27kDa protein 1; heat shock protein beta-1", "tax_id": 9823, "disease": "", "pathway": " (ssc:493184)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "15908467;16930837;17080460;23365273;24763551;24907481;29525670;33444678", "class_list": "", "function": "Effects of HSP27 gene expression on the resistance to Escherichia coli infection in piglets., [RefSeq, PubMed]; Extremely low frequency magnetic field exposure affected the cellular distribution of Hsp27; in particular a partial relocalization in the nucleus was observed., [RefSeq, PubMed]; HSP-27 and HSP-70 contribute to modulation of K(+) channel-induced pial artery dilation, [RefSeq, PubMed]; HSP27 expression is gut region- and cell type-specific in response to dietary components, microbes, and microbial metabolites to which the mucosa surface is exposed., [RefSeq, PubMed]; HSP27 in the retinas of 1-day-old piglets and showed that it was enhanced in the retinas of 6-month-old adult. And was seen mainly in ganglion cell bodies in the ganglion cell layer, and in some processes of astrocytes in the innermost nerve fiber layer., [RefSeq, PubMed]; Here, heat shock protein 27 (Hsp27) has been identified as a novel binding partner of NS5A, a protein functioning in classical swine fever virus genome replication. Further findings clearly demonstrate that the inhibition of viral replication by Hsp27 is mediated via the NF-kappaB signaling pathway., [RefSeq, PubMed]; It indicated that Hsp27 was required for porcine circovirus type 2 replication in PK-15 cells culture., [RefSeq, PubMed]; Small heat shock protein which functions as a molecular chaperone probably maintaining denatured proteins in a folding-competent state. Plays a role in stress resistance and actin organization. Through its molecular chaperone activity may regulate numerous biological processes including the phosphorylation and the axonal transport of neurofilament proteins., [UniProtKB, UniProtKB]; These results indicate that Hsp27 expression in the porcine gut could be associated with specific dietary fiber components but not the overall microbiota diversity., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 11, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0042802 identical protein binding;GO:0042803 protein homodimerization activity;GO:0051082 unfolded protein binding;GO:0044183 protein folding chaperone", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005819 spindle;GO:1904115 axon cytoplasm", "go_biological_process": "GO:0099641 anterograde axonal protein transport;GO:0043066 negative regulation of apoptotic process;GO:0006457 protein folding;GO:0001932 regulation of protein phosphorylation;GO:0009408 response to heat", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q5S1U1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q5XW65-1", "uniprot_id": "BPIA1_PIG", "mass": 25829.0, "length": 249, "protein_name": "BPI fold-containing family A member 1", "gene_name": "BPIFA1", "organism": "Pig", "refseq_name": "BPI fold-containing family A member 1 precursor", "refseq_ac": "NP_001005727", "gene_names_uniprotkb": "BPIFA1; PLUNC; SPLUNC1", "gene_names_refseq": "BPIFA1; PLUNC; SPLUNC1", "protein_names_uniprotkb": "BPI fold-containing family A member 1; Lung and nasal epithelium carcinoma-associated protein; Palate lung and nasal epithelium clone protein", "protein_names_refseq": "BPI fold-containing family A member 1 precursor; lung and nasal epithelium carcinoma-associated protein; palate lung and nasal epithelium clone protein; palate, lung and nasal epithelium associated; palate, lung and nasal epithelium carcinoma associated protein; protein Plunc", "tax_id": 9823, "disease": "", "pathway": " (ssc:449524)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15777615", "class_list": "", "function": "High expression level in trachea and lung tissue only, [RefSeq, PubMed]; Lipid-binding protein which shows high specificity for the surfactant phospholipid dipalmitoylphosphatidylcholine (DPPC). Plays a role in the innate immune responses of the upper airways. Reduces the surface tension in secretions from airway epithelia and inhibits the formation of biofilm by pathogenic Gram-negative bacteria, such as P.aeruginosa and K.pneumoniae. Negatively regulates proteolytic cleavage of SCNN1G, an event that is required for activation of the epithelial sodium channel (ENaC), and thereby contributes to airway surface liquid homeostasis and proper clearance of mucus. Plays a role in the airway inflammatory response after exposure to irritants. May attract macrophages and neutrophils., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q5XW64", "ec_number_list": "", "go_molecular_function": "GO:0008289 lipid binding", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0019731 antibacterial humoral response;GO:0043129 surfactant homeostasis;GO:0045087 innate immune response;GO:0061844 antimicrobial humoral immune response mediated by antimicrobial peptide;GO:0050891 multicellular organismal-level water homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q5XW65-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q66UW5-1", "uniprot_id": "ISG20_PIG", "mass": 20462.0, "length": 181, "protein_name": "Interferon-stimulated gene 20 kDa protein", "gene_name": "Isg20", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "Isg20", "gene_names_refseq": "", "protein_names_uniprotkb": "Interferon-stimulated gene 20 kDa protein; 3.1.13.1", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Interferon-induced antiviral exoribonuclease that acts mainly on single-stranded RNA. Inhibition of several viruses does not involve the degradation of viral RNAs, but rather the inhibition of translation of viral proteins. Exerts a translational control over a large panel of non-self RNA substrates while sparing endogenous transcripts. This activity correlates with the protein's ability to localize in cytoplasmic processing bodies. May also act as master regulator of over hundred interferon stimulated genes leading to viral genome translation inhibition (By similarity). May play additional roles in the maturation of snRNAs and rRNAs, and in ribosome biogenesis (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008859 exoribonuclease II activity;GO:0030620 U2 snRNA binding;GO:0046872 metal ion binding;GO:0004527 exonuclease activity;GO:0034511 U3 snoRNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005730 nucleolus;GO:0005737 cytoplasm;GO:0015030 Cajal body", "go_biological_process": "GO:0006396 RNA processing;GO:0045087 innate immune response;GO:0051607 defense response to virus;GO:0045071 negative regulation of viral genome replication;GO:0006364 rRNA processing", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q66UW5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q684M2-1", "uniprot_id": "ATG4D_PIG", "mass": 52429.0, "length": 469, "protein_name": "Cysteine protease ATG4D", "gene_name": "ATG4D", "organism": "Pig", "refseq_name": "cysteine protease ATG4D", "refseq_ac": "NP_001116551", "gene_names_uniprotkb": "ATG4D; APG4D", "gene_names_refseq": "APG4D; ATG4D", "protein_names_uniprotkb": "Cysteine protease ATG4D; 3.4.22.-; Autophagin-4; Autophagy-related protein 4 homolog D", "protein_names_refseq": "ATG4 autophagy related 4 homolog D; AUT-like 4, cysteine endopeptidase; autophagin-4; autophagy-related protein 4 homolog D; cysteine protease ATG4D", "tax_id": 9823, "disease": "", "pathway": " (ssc:100141400); (R-SSC-1632852)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins. The protease activity is required for proteolytic activation of ATG8 family proteins: cleaves the C-terminal amino acid of ATG8 proteins MAP1LC3 and GABARAPL2, to reveal a C-terminal glycine (By similarity). Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy (By similarity). In addition to the protease activity, also mediates delipidation of ATG8 family proteins. Catalyzes delipidation of PE-conjugated forms of ATG8 proteins during macroautophagy. Also involved in non-canonical autophagy, a parallel pathway involving conjugation of ATG8 proteins to single membranes at endolysosomal compartments, by catalyzing delipidation of ATG8 proteins conjugated to phosphatidylserine (PS) (By similarity). ATG4D plays a role in the autophagy-mediated neuronal homeostasis in the central nervous system. Compared to other members of the family (ATG4A, ATG4B or ATG4C), constitutes the major protein for the delipidation activity, while it promotes weak proteolytic activation of ATG8 proteins (By similarity). Involved in phagophore growth during mitophagy independently of its protease activity and of ATG8 proteins: acts by regulating ATG9A trafficking to mitochondria and promoting phagophore-endoplasmic reticulum contacts during the lipid transfer phase of mitophagy (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Plays a role as an autophagy regulator that links mitochondrial dysfunction with apoptosis. The mitochondrial import of ATG4D during cellular stress and differentiation may play important roles in the regulation of mitochondrial physiology, ROS, mitophagy and cell viability., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004197 cysteine-type endopeptidase activity;GO:0008234 cysteine-type peptidase activity;GO:0019786 protein-phosphatidylethanolamide deconjugating activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0000045 autophagosome assembly;GO:0015031 protein transport;GO:0016485 protein processing;GO:0006915 apoptotic process;GO:0006914 autophagy", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q684M2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1S5J8-1", "uniprot_id": "F1S5J8_PIG", "mass": 76700.0, "length": 683, "protein_name": "Long-chain-fatty-acid--CoA ligase", "gene_name": "ACSL5", "organism": "Pig", "refseq_name": "long-chain-fatty-acid--CoA ligase 5 isoform X1", "refseq_ac": "XP_013845942", "gene_names_uniprotkb": "ACSL5", "gene_names_refseq": "ACSL5", "protein_names_uniprotkb": "Long-chain-fatty-acid--CoA ligase; 6.2.1.15; 6.2.1.3; Acyl-CoA synthetase; Long-chain acyl-CoA synthetase", "protein_names_refseq": "long-chain-fatty-acid--CoA ligase 5 isoform X1", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-75876)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "I3LCL6", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0047676 arachidonate-CoA ligase activity;GO:0090434 oleoyl-CoA ligase activity", "go_cellular_component": "GO:0005741 mitochondrial outer membrane;GO:0005789 endoplasmic reticulum membrane;GO:0005739 mitochondrion;GO:0005783 endoplasmic reticulum;GO:0016020 membrane", "go_biological_process": "GO:0035338 long-chain fatty-acyl-CoA biosynthetic process;GO:0010747 positive regulation of long-chain fatty acid import across plasma membrane", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1S5J8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SIK9-1", "uniprot_id": "F1SIK9_PIG", "mass": 53874.0, "length": 464, "protein_name": "Septin", "gene_name": "SEPTIN7", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "SEPTIN7", "gene_names_refseq": "", "protein_names_uniprotkb": "Septin", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-5687128)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Required for normal progress through mitosis. Involved in cytokinesis. Required for normal association of CENPE with the kinetochore. Plays a role in ciliogenesis and collective cell movements. Forms a filamentous structure with SEPTIN12, SEPTIN6, SEPTIN2 and probably SEPTIN4 at the sperm annulus which is required for the structural integrity and motility of the sperm tail during postmeiotic differentiation., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005525 GTP binding;GO:0060090 molecular adaptor activity;GO:0003924 GTPase activity;GO:0042802 identical protein binding", "go_cellular_component": "GO:0005819 spindle;GO:0032154 cleavage furrow;GO:0005930 axoneme;GO:0000776 kinetochore;GO:0030496 midbody", "go_biological_process": "GO:0051301 cell division;GO:0007010 cytoskeleton organization;GO:0008104 intracellular protein localization;GO:0061640 cytoskeleton-dependent cytokinesis;GO:1902857 positive regulation of non-motile cilium assembly", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SIK9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SBF5-1", "uniprot_id": "F1SBF5_PIG", "mass": 58882.0, "length": 538, "protein_name": "Eyes absent homolog", "gene_name": "EYA2", "organism": "Pig", "refseq_name": "eyes absent homolog 2 isoform X3", "refseq_ac": "XP_020933054", "gene_names_uniprotkb": "EYA2", "gene_names_refseq": "EYA2", "protein_names_uniprotkb": "Eyes absent homolog; 3.1.3.48", "protein_names_refseq": "eyes absent homolog 2 isoform X3", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-5693565)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0046872 metal ion binding;GO:0004725 protein tyrosine phosphatase activity;GO:0000287 magnesium ion binding;GO:0140793 histone H2AXY142 phosphatase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol", "go_biological_process": "GO:0006281 DNA repair;GO:0006351 DNA-templated transcription;GO:0030154 cell differentiation;GO:0045739 positive regulation of DNA repair;GO:2001240 negative regulation of extrinsic apoptotic signaling pathway in absence of ligand", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SBF5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9TSW7-1", "uniprot_id": "Q9TSW7_PIG", "mass": 51675.0, "length": 466, "protein_name": "Alpha-1A adrenergic receptor", "gene_name": "ADRA1A", "organism": "Pig", "refseq_name": "alpha-1A adrenergic receptor", "refseq_ac": "NP_001116544", "gene_names_uniprotkb": "ADRA1A", "gene_names_refseq": "ADRA1A; alpha-1A", "protein_names_uniprotkb": "Alpha-1A adrenergic receptor; Alpha-1A adrenoreceptor; Alpha-1C adrenergic receptor", "protein_names_refseq": "adrenergic, alpha-1A-, receptor; alpha-1A adrenergic receptor", "tax_id": 9823, "disease": "", "pathway": " (ssc:100144471); (R-SSC-390696); (R-SSC-416476); (R-SSC-416482)", "pathway_count": 4, "publication_count": 2, "publication_id_list": "18516067;32543654", "class_list": "", "function": "Alpha-1 adrenergic receptors are G protein-coupled receptors for catecholamines that signal through the G(q) family of G proteins, including G(q) and G(11). Upon activation, they stimulate the phosphatidylinositol-calcium second messenger pathway, leading to calcium release from intracellular stores and activation of protein kinase C. ADRA1A binds the catecholamine ligands norepinephrine and epinephrine. Can also couple to G(14) protein. Nuclear ADRA1A forms heterooligomers with ADRA1B to regulate phenylephrine(PE)-stimulated ERK signaling in cardiac myocytes. At the plasma membrane, ADRA1A interacts with CAVIN4/MURC to regulates ERK activation in cardiomyocytes, contributing to the regulation of cardiac hypertrophy. Additionally, functions as a vasopressor in resistance arteries and plays a role in maintaining normal arterial blood pressure., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Results suggest that contraction of circular smooth muscle from the pig internal anal sphincter is mediated via alpha1A/L-adrenoceptors., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004937 alpha1-adrenergic receptor activity;GO:0046982 protein heterodimerization activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0031965 nuclear membrane;GO:0005901 caveola;GO:0005829 cytosol;GO:0005886 plasma membrane", "go_biological_process": "GO:0019229 regulation of vasoconstriction;GO:0055117 regulation of cardiac muscle contraction;GO:0007204 positive regulation of cytosolic calcium ion concentration;GO:0007267 cell-cell signaling;GO:0043410 positive regulation of MAPK cascade", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q9TSW7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q95M75-1", "uniprot_id": "RHBG_PIG", "mass": 49583.0, "length": 458, "protein_name": "Ammonium transporter Rh type B", "gene_name": "RHBG", "organism": "Pig", "refseq_name": "ammonium transporter Rh type B", "refseq_ac": "NP_999161", "gene_names_uniprotkb": "RHBG", "gene_names_refseq": "RHBG", "protein_names_uniprotkb": "Ammonium transporter Rh type B; Rh family type B glycoprotein; Rh type B glycoprotein; Rhesus blood group family type B glycoprotein", "protein_names_refseq": "Rh type B glycoprotein; ammonium transporter Rh type B; rh family type B glycoprotein; rhesus blood group family type B glycoprotein", "tax_id": 9823, "disease": "", "pathway": " (ssc:397056)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "11358367;32543654", "class_list": "", "function": "Ammonium transporter involved in the maintenance of acid-base homeostasis. Transports ammonium and its related derivative methylammonium across the basolateral plasma membrane of epithelial cells likely contributing to renal transepithelial ammonia transport and ammonia metabolism. May transport either NH4(+) or NH3 ammonia species predominantly mediating an electrogenic NH4(+) transport (By similarity). May act as a CO2 channel providing for renal acid secretion (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008519 ammonium channel activity;GO:0035379 carbon dioxide transmembrane transporter activity;GO:0030506 ankyrin binding", "go_cellular_component": "GO:0016323 basolateral plasma membrane;GO:0014731 spectrin-associated cytoskeleton", "go_biological_process": "GO:0070634 transepithelial ammonium transport;GO:0072488 ammonium transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q95M75-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q764N2-1", "uniprot_id": "CD3D_PIG", "mass": 19475.0, "length": 171, "protein_name": "T-cell surface glycoprotein CD3 delta chain", "gene_name": "CD3D", "organism": "Pig", "refseq_name": "T-cell surface glycoprotein CD3 delta chain precursor", "refseq_ac": "NP_998940", "gene_names_uniprotkb": "CD3D", "gene_names_refseq": "CD3D", "protein_names_uniprotkb": "T-cell surface glycoprotein CD3 delta chain; T-cell receptor T3 delta chain", "protein_names_refseq": "CD3 antigen delta chain; CD3 antigen, delta polypeptide; CD3d molecule; T-cell receptor T3 delta chain; T-cell surface glycoprotein CD3 delta chain precursor; T-cell surface glycoprotein CD3 delta chain; TcR CD3 delta-chain", "tax_id": 9823, "disease": "", "pathway": " (ssc:396661); (R-SSC-198933); (R-SSC-202424); (R-SSC-202427); (R-SSC-202430); (R-SSC-202433); (R-SSC-389948); (R-SSC-8856825); (R-SSC-8856828)", "pathway_count": 9, "publication_count": 3, "publication_id_list": "14681463;17652534;32543654", "class_list": "", "function": "In cystic teratomas of the ovary, CD1-positive Langerhans cells appeared to cross the basal membrane and penetrate the subepidermal tissue, and they were associated there with T-cell line lymphocytes (CD3 positive)., [RefSeq, PubMed]; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD247/CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of downstream signaling pathways. In addition of this role of signal transduction in T-cell activation, CD3D plays an essential role in thymocyte differentiation. Indeed, participates in correct intracellular TCR-CD3 complex assembly and surface expression. In absence of a functional TCR-CD3 complex, thymocytes are unable to differentiate properly. Interacts with CD4 and CD8 and thus serves to establish a functional link between the TCR and coreceptors CD4 and CD8, which is needed for activation and positive selection of CD4 or CD8 T-cells., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004888 transmembrane signaling receptor activity;GO:0042802 identical protein binding;GO:0032395 MHC class II receptor activity", "go_cellular_component": "GO:0009897 external side of plasma membrane;GO:0042105 alpha-beta T cell receptor complex;GO:0005886 plasma membrane", "go_biological_process": "GO:0007166 cell surface receptor signaling pathway;GO:0050852 T cell receptor signaling pathway;GO:0002250 adaptive immune response;GO:0045059 positive thymic T cell selection", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q764N2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q711P4-1", "uniprot_id": "CCL4_PIG", "mass": 10207.0, "length": 92, "protein_name": "C-C motif chemokine 4", "gene_name": "CCL4", "organism": "Pig", "refseq_name": "C-C motif chemokine 4 precursor", "refseq_ac": "NP_998944", "gene_names_uniprotkb": "CCL4; MIP1B; SCY4A", "gene_names_refseq": "CCL4; MIP-1BETA; MIP1b; SCY4A", "protein_names_uniprotkb": "C-C motif chemokine 4; MIP-1-beta; Macrophage inflammatory protein 1-beta; Small-inducible cytokine A4", "protein_names_refseq": "C-C motif chemokine 4 precursor; C-C motif chemokine 4; MIP-1-beta; chemokine (C-C motif) ligand 4; macrophage inflammatory protein 1-beta; small-inducible cytokine A4", "tax_id": 9823, "disease": "", "pathway": " (ssc:396668); (R-SSC-380108); (R-SSC-418594)", "pathway_count": 3, "publication_count": 2, "publication_id_list": "23102097;32543654", "class_list": "", "function": "In swine, IL-8, TNF-ALPHA, INOS AND MIP-1BETA were increased during mechanical ventilation in a time-related fashion., [RefSeq, PubMed]; Monokine with inflammatory and chemokinetic properties., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008009 chemokine activity;GO:0048020 CCR chemokine receptor binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005576 extracellular region", "go_biological_process": "GO:0006954 inflammatory response;GO:0030335 positive regulation of cell migration;GO:0061844 antimicrobial humoral immune response mediated by antimicrobial peptide;GO:0070098 chemokine-mediated signaling pathway;GO:0048245 eosinophil chemotaxis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q711P4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9N2G6-1", "uniprot_id": "IL7_PIG", "mass": 20161.0, "length": 176, "protein_name": "Interleukin-7", "gene_name": "IL7", "organism": "Pig", "refseq_name": "interleukin-7 precursor", "refseq_ac": "NP_999300", "gene_names_uniprotkb": "IL7", "gene_names_refseq": "IL-7; IL7", "protein_names_uniprotkb": "Interleukin-7; IL-7", "protein_names_refseq": "Interleukin-7; interleukin-7 precursor", "tax_id": 9823, "disease": "", "pathway": " (ssc:397253); (R-SSC-1266695)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "11342229;11474182;32543654", "class_list": "", "function": "Hematopoietic cytokine that plays an essential role in the development, expansion, and survival of naive and memory T-cells and B-cells thereby regulating the number of mature lymphocytes and maintaining lymphoid homeostasis., [UniProtKB, UniProtKB, UniProtKB]; Hematopoietic growth factor capable of stimulating the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation., [UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005139 interleukin-7 receptor binding;GO:0005125 cytokine activity;GO:0008083 growth factor activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0001961 positive regulation of cytokine-mediated signaling pathway;GO:0006955 immune response;GO:0032722 positive regulation of chemokine production;GO:0038111 interleukin-7-mediated signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9N2G6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q8SPR7-1", "uniprot_id": "PLCD4_PIG", "mass": 88075.0, "length": 772, "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4", "gene_name": "PLCD4", "organism": "Pig", "refseq_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4", "refseq_ac": "NP_999217", "gene_names_uniprotkb": "PLCD4", "gene_names_refseq": "PLCD4", "protein_names_uniprotkb": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4; 3.1.4.11; PLC-delta-4; Phosphoinositide phospholipase C-delta-4; Phospholipase C-delta-4", "protein_names_refseq": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4; PLC-delta-4; phosphoinositide phospholipase C-delta-4", "tax_id": 9823, "disease": "", "pathway": " (ssc:397119); (R-SSC-1855204)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Hydrolyzes the phosphatidylinositol 4,5-bisphosphate (PIP2) to generate 2 second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). DAG mediates the activation of protein kinase C (PKC), while IP3 releases Ca(2+) from intracellular stores. Required for acrosome reaction in sperm during fertilization, probably by acting as an important enzyme for intracellular Ca(2+) mobilization in the zona pellucida-induced acrosome reaction. May play a role in cell growth. Modulates the liver regeneration in cooperation with nuclear PKC. Overexpression up-regulates the Erk signaling pathway and proliferation (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004435 phosphatidylinositol-4,5-bisphosphate phospholipase C activity;GO:0005509 calcium ion binding;GO:0001965 G-protein alpha-subunit binding;GO:0120548 phosphatidylinositol phospholipase C activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005783 endoplasmic reticulum;GO:0005886 plasma membrane;GO:0005829 cytosol;GO:0016020 membrane", "go_biological_process": "GO:0035556 intracellular signal transduction;GO:0016042 lipid catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q8SPR7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9BDK6-1", "uniprot_id": "AT1B4_PIG", "mass": 41311.0, "length": 355, "protein_name": "Protein ATP1B4", "gene_name": "ATP1B4", "organism": "Pig", "refseq_name": "protein ATP1B4", "refseq_ac": "NP_999297", "gene_names_uniprotkb": "ATP1B4", "gene_names_refseq": "ATP1B4", "protein_names_uniprotkb": "Protein ATP1B4; X,K-ATPase subunit beta-m; X/potassium-transporting ATPase subunit beta-m", "protein_names_refseq": "ATPase, (Na+)/K+ transporting, beta 4 polypeptide; X,K-ATPase beta-m subunit; X/potassium-transporting ATPase subunit beta-m; glycoprotein; protein ATP1B4; x,K-ATPase subunit beta-m", "tax_id": 9823, "disease": "", "pathway": " (ssc:397245); (R-SSC-2173795)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "14656723;21855530;32543654", "class_list": "", "function": "May act as a transcriptional coregulator during muscle development through its interaction with SNW1. Has lost its ancestral function as a Na,K-ATPase beta-subunit (By similarity)., [UniProtKB, UniProtKB, UniProtKB]; The results of direct analysis of the purified native eutherian BetaM protein provide first insights into structural properties underlying its entirely new evolutionarily acquired functions., [RefSeq, PubMed]; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9BDK5", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005635 nuclear envelope;GO:0005637 nuclear inner membrane;GO:0005890 sodium:potassium-exchanging ATPase complex", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006355 regulation of DNA-templated transcription;GO:0006813 potassium ion transport;GO:0006814 sodium ion transport", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9BDK6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q867C0-1", "uniprot_id": "RAMP1_PIG", "mass": 16760.0, "length": 148, "protein_name": "Receptor activity-modifying protein 1", "gene_name": "RAMP1", "organism": "Pig", "refseq_name": "receptor activity-modifying protein 1 precursor", "refseq_ac": "NP_999364", "gene_names_uniprotkb": "RAMP1", "gene_names_refseq": "RAMP1", "protein_names_uniprotkb": "Receptor activity-modifying protein 1", "protein_names_refseq": "receptor activity-modifying protein 1 precursor", "tax_id": 9823, "disease": "", "pathway": " (ssc:397401)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Accessory protein that interacts with and modulates the function of G protein-coupled receptors including calcitonin gene-related peptide type 1 receptor (CALCRL) and calcitonin receptor (CALCR). Required for the transport of CALCRL to the plasma membrane. Together with CALCRL, form the receptor complex for the calcitonin gene-related peptides CGRP1/CALCA and CGRP2/CALCB. Together with CALCR, form the AMYR1 receptor complex for amylin/IAPP and CGRP1/CALCA., [UniProtKB, UniProtKB]; Accessory protein that interacts with and modulates the function of G-protein coupled receptors including calcitonin gene-related peptide type 1 receptor (CALCRL) and calcitonin receptor (CALCR). Required for the transport of CALCRL to the plasma membrane. Together with CALCRL, form the receptor complex for the calcitonin gene-related peptides CGRP1/CALCA and CGRP2/CALCB. Together with CALCR, form the AMYR1 receptor complex for amylin/IAPP and CGRP1/CALCA., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0015026 coreceptor activity;GO:0001635 calcitonin gene-related peptide receptor activity;GO:0097643 amylin receptor activity;GO:1990407 calcitonin gene-related peptide binding", "go_cellular_component": "GO:0009986 cell surface;GO:1990406 CGRP receptor complex;GO:0005886 plasma membrane", "go_biological_process": "GO:0001525 angiogenesis;GO:0006886 intracellular protein transport;GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0031623 receptor internalization;GO:0072659 protein localization to plasma membrane", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q867C0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9GJT2-1", "uniprot_id": "ESTD_PIG", "mass": 31482.0, "length": 282, "protein_name": "S-formylglutathione hydrolase", "gene_name": "ESD", "organism": "Pig", "refseq_name": "S-formylglutathione hydrolase", "refseq_ac": "NP_999225", "gene_names_uniprotkb": "ESD", "gene_names_refseq": "ESD; Es10", "protein_names_uniprotkb": "S-formylglutathione hydrolase; 3.1.2.12; Esterase D; FGH", "protein_names_refseq": "FGH; S-formylglutathione hydrolase", "tax_id": 9823, "disease": "", "pathway": " (ssc:397127); (R-SSC-156590)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "11167536;27267271;32543654", "class_list": "", "function": "Our findings demonstrate a new mechanism evolved by ESD to enhance type I IFN signal transduction and suppress viral replication during Foot-and-mouth disease virus infection., [RefSeq, PubMed]; Serine hydrolase involved in the detoxification of formaldehyde., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q9GM98", "ec_number_list": "", "go_molecular_function": "GO:0042802 identical protein binding;GO:0052689 carboxylic ester hydrolase activity;GO:0018738 S-formylglutathione hydrolase activity", "go_cellular_component": "GO:0005829 cytosol;GO:0031410 cytoplasmic vesicle;GO:0005737 cytoplasm", "go_biological_process": "GO:0046294 formaldehyde catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9GJT2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q95J68-1", "uniprot_id": "IL13_PIG", "mass": 14452.0, "length": 131, "protein_name": "Interleukin-13", "gene_name": "IL13", "organism": "Pig", "refseq_name": "interleukin-13 precursor", "refseq_ac": "NP_998968", "gene_names_uniprotkb": "IL13", "gene_names_refseq": "IL-13; IL13; L13", "protein_names_uniprotkb": "Interleukin-13; IL-13", "protein_names_refseq": "interleukin-13 precursor", "tax_id": 9823, "disease": "", "pathway": " (ssc:396721); (R-SSC-6785807)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Cytokine that plays important roles in allergic inflammation and immune response to parasite infection. Synergizes with IL2 in regulating interferon-gamma synthesis. Stimulates B-cell proliferation, and activation of eosinophils, basophils, and mast cells (By similarity). Plays an important role in controlling IL33 activity by modulating the production of transmembrane and soluble forms of interleukin-1 receptor-like 1/IL1RL1 (By similarity). Displays the capacity to antagonize Th1-driven proinflammatory immune response and downregulates synthesis of many proinflammatory cytokines including IL1, IL6, IL10, IL12 and TNF through a mechanism that partially involves suppression of NF-kappa-B (By similarity). Also functions on nonhematopoietic cells, including endothelial cells where it induces vascular cell adhesion protein 1/VCAM1, which is important in the recruitment of eosinophils. Exerts its biological effects through its receptors which comprises the IL4R chain and the IL13RA1 chain, to activate JAK1 and TYK2, leading to the activation of STAT6. Aside from IL13RA1, another receptor IL13RA2 acts as a high affinity decoy for IL13 and mediates internalization and depletion of extracellular IL13 (By similarity). Induces inflammatory response in esophageal epithelium which results in a dysregulation of desmosome intercellular adhesion junctions, via down-regulation of DSG1 (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 4, "predicted_n_glycosites": 4, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005144 interleukin-13 receptor binding;GO:0005125 cytokine activity;GO:0005126 cytokine receptor binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005737 cytoplasm;GO:0009897 external side of plasma membrane;GO:0005576 extracellular region", "go_biological_process": "GO:0043032 positive regulation of macrophage activation;GO:0006954 inflammatory response;GO:0006955 immune response;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0050728 negative regulation of inflammatory response", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q95J68-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q75QW1-1", "uniprot_id": "EPCAM_PIG", "mass": 34833.0, "length": 314, "protein_name": "Epithelial cell adhesion molecule", "gene_name": "EPCAM; TACSTD1", "organism": "Pig", "refseq_name": "epithelial cell adhesion molecule precursor", "refseq_ac": "NP_999584", "gene_names_uniprotkb": "EPCAM; TACSTD1; EPCAM", "gene_names_refseq": "EGP; EPCAM; Ep-CAM; TACSTD1", "protein_names_uniprotkb": "Epithelial cell adhesion molecule; Ep-CAM; Tumor-associated calcium signal transducer 1", "protein_names_refseq": "epithelial cell adhesion molecule precursor; epithelial glycoprotein; tumor-associated calcium signal transducer 1", "tax_id": 9823, "disease": "", "pathway": " (ssc:403163); (R-SSC-202733)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "15507398;32543654", "class_list": "", "function": "Ep-CAM may act as a physical homophilic interaction molecule between IELs and IECs at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection [Ep-CAM], [RefSeq, PubMed]; May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E (By similarity)., [UniProtKB, PubMed, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; May function as a growth factor receptor., [UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0098641 cadherin binding involved in cell-cell adhesion;GO:0044877 protein-containing complex binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005923 bicellular tight junction;GO:0016328 lateral plasma membrane;GO:0009986 cell surface;GO:0016323 basolateral plasma membrane", "go_biological_process": "GO:0008284 positive regulation of cell population proliferation;GO:2000648 positive regulation of stem cell proliferation;GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0048863 stem cell differentiation;GO:0001657 ureteric bud development", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q75QW1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q767K6-1", "uniprot_id": "DHX16_PIG", "mass": 119648.0, "length": 1045, "protein_name": "Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16", "gene_name": "DHX16", "organism": "Pig", "refseq_name": "pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16", "refseq_ac": "NP_001116578", "gene_names_uniprotkb": "DHX16; DDX16", "gene_names_refseq": "DDX16; DHX16", "protein_names_uniprotkb": "Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16; 3.6.4.13; DEAH-box protein 16", "protein_names_refseq": "DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 16; DEAH-box protein 16; Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16; pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16", "tax_id": 9823, "disease": "", "pathway": " (ssc:100144456)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "14673549;32543654", "class_list": "", "function": "Required for pre-mRNA splicing as a component of the spliceosome. Contributes to pre-mRNA splicing after spliceosome formation and prior to the first transesterification reaction. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs. Also plays a role in innate antiviral response by acting as a pattern recognition receptor sensing splicing signals in viral RNA. Mechanistically, TRIM6 promotes the interaction between unanchored 'Lys-48'-polyubiquitin chains and DHX16, leading to DHX16 interaction with RIGI and ssRNA to amplify RIGI-dependent innate antiviral immune responses., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0060090 molecular adaptor activity;GO:0003723 RNA binding;GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0043130 ubiquitin binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005737 cytoplasm;GO:0071005 U2-type precatalytic spliceosome;GO:0005681 spliceosomal complex", "go_biological_process": "GO:0000398 mRNA splicing, via spliceosome;GO:0140374 antiviral innate immune response;GO:0045087 innate immune response", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q767K6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q7M2W6-1", "uniprot_id": "CRYAB_PIG", "mass": 20129.0, "length": 175, "protein_name": "Alpha-crystallin B chain", "gene_name": "CRYAB", "organism": "Pig", "refseq_name": "alpha-crystallin B chain", "refseq_ac": "XP_005667376", "gene_names_uniprotkb": "CRYAB", "gene_names_refseq": "CRYAB", "protein_names_uniprotkb": "Alpha-crystallin B chain; Alpha(B)-crystallin", "protein_names_refseq": "alpha-crystallin B chain", "tax_id": 9823, "disease": "", "pathway": " (ssc:100519789); (R-SSC-3371571)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "32543654;9514893", "class_list": "", "function": "May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions. In lens epithelial cells, stabilizes the ATP6V1A protein, preventing its degradation by the proteasome (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0042803 protein homodimerization activity;GO:0046872 metal ion binding;GO:0051082 unfolded protein binding;GO:0005212 structural constituent of eye lens;GO:0001540 amyloid-beta binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005764 lysosome;GO:0032991 protein-containing complex", "go_biological_process": "GO:0043066 negative regulation of apoptotic process;GO:0045892 negative regulation of DNA-templated transcription;GO:0009408 response to heat;GO:0042026 protein refolding;GO:0009892 negative regulation of metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q7M2W6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q6QN13-1", "uniprot_id": "IOD1_PIG", "mass": 28888.0, "length": 249, "protein_name": "Type I iodothyronine deiodinase", "gene_name": "DIO1", "organism": "Pig", "refseq_name": "type I iodothyronine deiodinase", "refseq_ac": "NP_001001627", "gene_names_uniprotkb": "DIO1", "gene_names_refseq": "D1; DIO1", "protein_names_uniprotkb": "Type I iodothyronine deiodinase; 1.21.99.3; 1.21.99.4; 5DI; DIOI; Type 1 DI; Type-I 5'-deiodinase", "protein_names_refseq": "5DI; DIOI; deiodinase, iodothyronine type I; type 1 DI; type I iodothyronine deiodinase; type-I 5'-deiodinase", "tax_id": 9823, "disease": "", "pathway": " (ssc:414380); (R-SSC-350864)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "15192045;32543654", "class_list": "", "function": "D1 activity in liver and kidney was increased in T4-treated pigs., [RefSeq, PubMed]; Plays a crucial role in the metabolism of thyroid hormones (TH) and has specific roles in TH activation and inactivation by deiodination (PubMed:15192045). Catalyzes the deiodination of L-thyroxine (T4) to 3,5,3'-triiodothyronine (T3) and 3,3',5'-triiodothyronine (rT3) to 3,3'-diiodothyronine (3,3'-T2) via outer-ring deiodination (ORD) (PubMed:15192045). Catalyzes the deiodination of T4 to rT3, T3 to 3,3'-T2, 3,5-diiodothyronine (3,5-T2) to 3-monoiodothyronine (3-T1) and 3,3'-T2 to 3-T1 via inner-ring deiodination (IRD) (By similarity). Catalyzes the deiodination of 3',5'-diiodothyronine (3',5'-T2) to 3'-monoiodothyronine (3'-T1) via ORD (By similarity). Catalyzes the phenolic ring deiodinations of 3,3',5'-triiodothyronamine, 3',5'-diiodothyronamine and 3,3'-diiodothyronamine as well as tyrosyl ring deiodinations of 3,5,3'-triiodothyronamine and 3,5-diiodothyronamine (By similarity). Catalyzes the deiodination of L-thyroxine sulfate and 3,3',5-triiodo-L-thyronine sulfate via IRD and of 3,3',5'-triiodo-L-thyronine sulfate via ORD (By similarity)., [UniProtKB, PubMed, UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0033798 thyroxine 5-deiodinase activity;GO:0004800 thyroxine 5'-deiodinase activity", "go_cellular_component": "GO:0016323 basolateral plasma membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0042404 thyroid hormone catabolic process;GO:0042446 hormone biosynthetic process;GO:0006520 amino acid metabolic process;GO:0042403 thyroid hormone metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q6QN13-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SA11-1", "uniprot_id": "F1SA11_PIG", "mass": 62148.0, "length": 547, "protein_name": "TNF receptor-associated factor", "gene_name": "TRAF3", "organism": "Pig", "refseq_name": "TNF receptor-associated factor 3 isoform X2", "refseq_ac": "XP_020937289", "gene_names_uniprotkb": "TRAF3", "gene_names_refseq": "TRAF3", "protein_names_uniprotkb": "TNF receptor-associated factor; 2.3.2.27", "protein_names_refseq": "TNF receptor-associated factor 3 isoform X2", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-5668541); (R-SSC-5676594); (R-SSC-5689896); (R-SSC-936964); (R-SSC-9824878)", "pathway_count": 5, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "K9IW74", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0019901 protein kinase binding;GO:0042802 identical protein binding;GO:0031625 ubiquitin protein ligase binding;GO:0031996 thioesterase binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0010008 endosome membrane;GO:0009898 cytoplasmic side of plasma membrane;GO:0035631 CD40 receptor complex", "go_biological_process": "GO:0032648 regulation of interferon-beta production;GO:0007166 cell surface receptor signaling pathway;GO:0045087 innate immune response;GO:0006915 apoptotic process;GO:0030162 regulation of proteolysis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SA11-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q69DK8-1", "uniprot_id": "C1S_PIG", "mass": 76101.0, "length": 687, "protein_name": "Complement C1s subcomponent", "gene_name": "", "organism": "Pig", "refseq_name": "complement C1s subcomponent precursor", "refseq_ac": "NP_001005349", "gene_names_uniprotkb": "", "gene_names_refseq": "C1S", "protein_names_uniprotkb": "Complement C1s subcomponent; 3.4.21.42; C1 esterase; Complement component 1 subcomponent s", "protein_names_refseq": "C1 esterase; complement C1s subcomponent precursor; complement C1s subcomponent; complement component 1 subcomponent s; complement component 1, s subcomponent; complement component C1s", "tax_id": 9823, "disease": "", "pathway": " (ssc:397274)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "C1s B chain is a serine protease that combines with C1q and C1r to form C1, the first component of the classical pathway of the complement system. C1r activates C1s so that it can, in turn, activate C2 and C4 (By similarity). Also cleaves IGFBP5 and thereby inhibits the trophic effects of IGF1., [UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 2, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004252 serine-type endopeptidase activity;GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0006508 proteolysis;GO:0045087 innate immune response;GO:0006958 complement activation, classical pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q69DK8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q6J1I8-1", "uniprot_id": "RN114_PIG", "mass": 25629.0, "length": 228, "protein_name": "E3 ubiquitin-protein ligase RNF114", "gene_name": "RNF114", "organism": "Pig", "refseq_name": "E3 ubiquitin-protein ligase RNF114", "refseq_ac": "NP_001001869", "gene_names_uniprotkb": "RNF114; ZNF313", "gene_names_refseq": "RNF114; ZFP313; ZNF313", "protein_names_uniprotkb": "E3 ubiquitin-protein ligase RNF114; 2.3.2.27; RING finger protein 114; RING-type E3 ubiquitin transferase RNF114; Zinc finger protein 313", "protein_names_refseq": "E3 ubiquitin-protein ligase RNF114; RING-type E3 ubiquitin transferase RNF114; zinc finger protein 313", "tax_id": 9823, "disease": "", "pathway": " (ssc:414917); (R-SSC-983168)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "31413123;32605740;37855431", "class_list": "", "function": "DCAF13 and RNF114 participate in the regulation of early porcine embryo development. Publication Status: Online-Only, [RefSeq, PubMed]; E3 ubiquitin-protein ligase that promotes the ubiquitination of various substrates. In turn, participates in the regulation of many biological processes including cell cycle, apoptosis, osteoclastogenesis as well as innate or adaptive immunity. Acts as negative regulator of NF-kappa-B-dependent transcription by promoting the ubiquitination and stabilization of the NF-kappa-B inhibitor TNFAIP3. May promote the ubiquitination of TRAF6 as well. Also acts as a negative regulator of T-cell activation. Inhibits cellular dsRNA responses and interferon production by targeting MAVS component for proteasomal degradation. Ubiquitinates the CDK inhibitor CDKN1A leading to its degradationand probably also CDKN1B and CDKN1C. This activity stimulates cell cycle G1-to-S phase transition and suppresses cellular senescence. May play a role in spermatogenesis (By similarity). Inhibits classical swine fever virus replication by mediating 'K27'-linked ubiquitination of viral NS4B and inducing its degradation via the proteasome (PubMed:31413123)., [UniProtKB, UniProtKB, PubMed]; Proteasomal degradation of nonstructural protein 12 by RNF114 suppresses porcine reproductive and respiratory syndrome virus replication., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 2, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0061630 ubiquitin protein ligase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005829 cytosol", "go_biological_process": "GO:0007283 spermatogenesis;GO:0030154 cell differentiation;GO:0000209 protein polyubiquitination;GO:0006511 ubiquitin-dependent protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q6J1I8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q6JTA8-1", "uniprot_id": "PRLR_PIG", "mass": 69573.0, "length": 625, "protein_name": "Prolactin receptor", "gene_name": "PRLR", "organism": "Pig", "refseq_name": "prolactin receptor precursor", "refseq_ac": "NP_001001868", "gene_names_uniprotkb": "PRLR", "gene_names_refseq": "PRLR; pPRLR-SF", "protein_names_uniprotkb": "Prolactin receptor; PRL-R", "protein_names_refseq": "PRL-R; prolactin receptor precursor", "tax_id": 9823, "disease": "", "pathway": " (ssc:414916); (R-SSC-1170546); (R-SSC-982772)", "pathway_count": 3, "publication_count": 9, "publication_id_list": "16682755;16864857;17284423;24712415;25318178;25358647;26255464;34248262;9321486", "class_list": "", "function": "A report of greater than expected levels of amino acid variability within the intracellular domain of the porcine PRLR, which have been associated with differences in ovulation in sows and the preweaning survivability of piglets is presented., [RefSeq, PubMed]; Alternative splicing of transcripts from nine first exons of the porcine PRLR (pPRLR) gene are differentially expressed in various tissues., [RefSeq, PubMed]; Associations between genotypes of the prolactin receptor (PRLR) gene and swine reproductive, growth and meat traits were determined., [RefSeq, PubMed]; Data showed that sows with genotype AB in PRLR gene had a significantly higher frequency of lateral-lying-to- other-posture trait and percentage of sow-terminated nursing trait than sows with the AA and BB genotypes., [RefSeq, PubMed]; Evaluation of reproductive traits and ovarian and uterine morphology of sows with different genotypes for the estrogen receptor, prolactin receptor, and follicle-stimulating hormone subunit beta genes., [RefSeq, PubMed]; Found associations between PRLR genotype and ejaculate volume, sperm concentration, percentage of live sperm, and number of live sperm in the ejaculate, [RefSeq, PubMed]; PRLR was identified as down-regulated in the oviduct of immotile short tail sperm (ISTS) homozygous sows. The methylation pattern of the PRLR gene region appeared unaffected., [RefSeq, PubMed]; The effects of prolactin receptor and beta-casein genotype on the nutritive value of sow milk are reported., [RefSeq, PubMed]; This is a receptor for the anterior pituitary hormone prolactin., [UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "O46679;Q6JTA9;Q6JTB0", "ec_number_list": "", "go_molecular_function": "GO:0046872 metal ion binding;GO:0017046 peptide hormone binding;GO:0019955 cytokine binding;GO:0004925 prolactin receptor activity", "go_cellular_component": "GO:0043235 receptor complex;GO:0009897 external side of plasma membrane", "go_biological_process": "GO:0008284 positive regulation of cell population proliferation;GO:0019221 cytokine-mediated signaling pathway", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "Q6JTA8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q6PQZ3-1", "uniprot_id": "INSI2_PIG", "mass": 24791.0, "length": 225, "protein_name": "Insulin-induced gene 2 protein", "gene_name": "INSIG2", "organism": "Pig", "refseq_name": "insulin-induced gene 2 protein", "refseq_ac": "NP_001123440", "gene_names_uniprotkb": "INSIG2", "gene_names_refseq": "INSIG-2; INSIG2", "protein_names_uniprotkb": "Insulin-induced gene 2 protein; INSIG-2", "protein_names_refseq": "insulin-induced gene 2 protein; insulin-induced membrane protein 2", "tax_id": 9823, "disease": "", "pathway": " (ssc:100170127)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "15771747;26965892", "class_list": "", "function": "FASN gene is a promising marker for subcutaneous fat tissue accumulation, while INSIG2 is a promising marker for FA composition, [RefSeq, PubMed]; Oxysterol-binding protein that mediates feedback control of cholesterol synthesis by controlling both endoplasmic reticulum to Golgi transport of SCAP and degradation of HMGCR. Acts as a negative regulator of cholesterol biosynthesis by mediating the retention of the SCAP-SREBP complex in the endoplasmic reticulum, thereby blocking the processing of sterol regulatory element-binding proteins (SREBPs) SREBF1/SREBP1 and SREBF2/SREBP2. Binds oxysterol, including 22-hydroxycholesterol, 24-hydroxycholesterol, 25-hydroxycholesterol and 27-hydroxycholesterol, regulating interaction with SCAP and retention of the SCAP-SREBP complex in the endoplasmic reticulum. In presence of oxysterol, interacts with SCAP, retaining the SCAP-SREBP complex in the endoplasmic reticulum, thereby preventing SCAP from escorting SREBF1/SREBP1 and SREBF2/SREBP2 to the Golgi. Sterol deprivation or phosphorylation by PCK1 reduce oxysterol-binding, disrupting the interaction between INSIG2 and SCAP, thereby promoting Golgi transport of the SCAP-SREBP complex, followed by processing and nuclear translocation of SREBF1/SREBP1 and SREBF2/SREBP2. Also regulates cholesterol synthesis by regulating degradation of HMGCR: initiates the sterol-mediated ubiquitin-mediated endoplasmic reticulum-associated degradation (ERAD) of HMGCR via recruitment of the reductase to the ubiquitin ligase RNF139., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q5Y8D7", "ec_number_list": "", "go_molecular_function": "GO:0008142 oxysterol binding;GO:0140311 protein sequestering activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0032937 SREBP-SCAP-Insig complex", "go_biological_process": "GO:0032869 cellular response to insulin stimulus;GO:0006695 cholesterol biosynthetic process;GO:0032933 SREBP signaling pathway;GO:0036316 SREBP-SCAP complex retention in endoplasmic reticulum", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q6PQZ3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q6PWT7-1", "uniprot_id": "CCS_PIG", "mass": 29397.0, "length": 274, "protein_name": "Copper chaperone for superoxide dismutase", "gene_name": "CCS", "organism": "Pig", "refseq_name": "copper chaperone for superoxide dismutase", "refseq_ac": "NP_001001866", "gene_names_uniprotkb": "CCS", "gene_names_refseq": "CCS", "protein_names_uniprotkb": "Copper chaperone for superoxide dismutase; Superoxide dismutase copper chaperone", "protein_names_refseq": "copper chaperone for superoxide dismutase; superoxide dismutase copper chaperone", "tax_id": 9823, "disease": "", "pathway": " (ssc:414913)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15265083", "class_list": "", "function": "Delivers copper to copper zinc superoxide dismutase (SOD1)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005507 copper ion binding;GO:0016532 superoxide dismutase copper chaperone activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0019430 removal of superoxide radicals", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q6PWT7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q6QN11-1", "uniprot_id": "IOD3_PIG", "mass": 34042.0, "length": 305, "protein_name": "Thyroxine 5-deiodinase", "gene_name": "DIO3", "organism": "Pig", "refseq_name": "thyroxine 5-deiodinase", "refseq_ac": "NP_001001625", "gene_names_uniprotkb": "DIO3", "gene_names_refseq": "5DIII; DIO3; DIOIII", "protein_names_uniprotkb": "Thyroxine 5-deiodinase; 1.21.99.3; 5DIII; DIOIII; Type 3 DI; Type III iodothyronine deiodinase", "protein_names_refseq": "Type 3 DI; Type-III 5'-deiodinase; deiodinase, iodothyronine type III; iodothyronine deiodinase type III; thyroxine 5-deiodinase; type III iodothyronine deiodinase", "tax_id": 9823, "disease": "", "pathway": " (ssc:414378); (R-SSC-350864)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "15192045;21660470;22393372", "class_list": "", "function": "DIO3 gene polymorphism was significantly associated with almost all fat deposition and carcass traits., [RefSeq, PubMed]; Expression of D3 was observed in cerebrum and was positively regulated by thyroid state., [RefSeq, PubMed]; Plays a crucial role in the metabolism of thyroid hormones (TH) and has specific roles in TH activation and inactivation by deiodination, particularly in different tissues. Catalyzes the deiodination of L-thyroxine (T4) to 3,3',5'-triiodothyronine (rT3), 3,5-diiodothyronine (3,5-T2) to 3-monoiodothyronine (3-T1), rT3 to 3',5'-diiodothyronine (3',5'-T2) and 3,3'-diiodothyronine (3,3'-T2) to 3'-monoiodothyronine (3'-T1) via inner-ring deiodination (IRD) (By similarity). Catalyzes the deiodination of 3,5,3'-triiodothyronine (T3) to 3,3'-diiodothyronine (3,3'-T2) via IRD (PubMed:15192045). Catalyzes the deiodination of 3-T1 to L-thyronine (T0) via outer-ring deiodination (ORD) (By similarity). Catalyzes the tyrosyl ring deiodinations of 3,3',5,5'-tetraiodothyronamine, 3,3',5'-triiodothyronamine, 3,5,3'-triiodothyronamine, 3,5-diiodothyronamine, 3,3'-diiodothyronamine and 3-iodothyronamine (By similarity)., [UniProtKB, PubMed, UniProtKB]; The imprinted gene DIO3 is a candidate gene for litter size in pigs, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0033798 thyroxine 5-deiodinase activity;GO:0004800 thyroxine 5'-deiodinase activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0010008 endosome membrane", "go_biological_process": "GO:0042404 thyroid hormone catabolic process;GO:0042446 hormone biosynthetic process;GO:0042403 thyroid hormone metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q6QN11-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q6QN12-1", "uniprot_id": "IOD2_PIG", "mass": 30376.0, "length": 269, "protein_name": "Type II iodothyronine deiodinase", "gene_name": "DIO2", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "DIO2", "gene_names_refseq": "", "protein_names_uniprotkb": "Type II iodothyronine deiodinase; 1.21.99.4; 5DII; DIOII; Type 2 DI; Type-II 5'-deiodinase", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "15192045", "class_list": "", "function": "Plays a crucial role in the metabolism of thyroid hormones (TH) and has specific roles in TH activation and inactivation by deiodination (PubMed:15192045).Catalyzes the deiodination of L-thyroxine (T4) to 3,5,3'-triiodothyronine (T3) and 3,3',5'-triiodothyronine (rT3) to 3,3'-diiodothyronine (3,3'-T2) via outer-ring deiodination (ORD) (PubMed:15192045). Catalyzes the deiodination of 3',5'-diiodothyronine (3',5'-T2) to 3'-monoiodothyronine (3'-T1) via ORD (By similarity). Catalyzes the phenolic ring deiodinations of 3,3',5'-triiodothyronamine and 3',5'- diiodothyronamine (By similarity)., [UniProtKB, PubMed, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004800 thyroxine 5'-deiodinase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0042404 thyroid hormone catabolic process;GO:0042446 hormone biosynthetic process;GO:0042403 thyroid hormone metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q6QN12-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q6QRN9-1", "uniprot_id": "ADT3_PIG", "mass": 32920.0, "length": 298, "protein_name": "ADP/ATP translocase 3", "gene_name": "SLC25A6", "organism": "Pig", "refseq_name": "ADP/ATP translocase 3", "refseq_ac": "NP_999583", "gene_names_uniprotkb": "SLC25A6; AAC3; ANT3", "gene_names_refseq": "SLC25A6", "protein_names_uniprotkb": "ADP/ATP translocase 3; ADP,ATP carrier protein 3; ANT 3; Adenine nucleotide translocator 3; Solute carrier family 25 member 6", "protein_names_refseq": "ADP,ATP carrier protein 3; ADP/ATP translocase 3; ANT 3; adenine nucleotide translocator 3; adenine nucleotide translocator), member 6; mitochondrial solute carrier family 25 member 6; solute carrier family 25 (mitochondrial carrier", "tax_id": 9823, "disease": "", "pathway": " (ssc:403155)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "ADP:ATP antiporter that mediates import of ADP into the mitochondrial matrix for ATP synthesis, and export of ATP out to fuel the cell (By similarity). Cycles between the cytoplasmic-open state (c-state) and the matrix-open state (m-state): operates by the alternating access mechanism with a single substrate-binding site intermittently exposed to either the cytosolic (c-state) or matrix (m-state) side of the inner mitochondrial membrane (By similarity). In addition to its ADP:ATP antiporter activity, also involved in mitochondrial uncoupling and mitochondrial permeability transition pore (mPTP) activity (By similarity). Plays a role in mitochondrial uncoupling by acting as a proton transporter: proton transport uncouples the proton flows via the electron transport chain and ATP synthase to reduce the efficiency of ATP production and cause mitochondrial thermogenesis. Proton transporter activity is inhibited by ADP:ATP antiporter activity, suggesting that SLC25A6/ANT3 acts as a master regulator of mitochondrial energy output by maintaining a delicate balance between ATP production (ADP:ATP antiporter activity) and thermogenesis (proton transporter activity). Proton transporter activity requires free fatty acids as cofactor, but does not transport it (By similarity). Also plays a key role in mPTP opening, a non-specific pore that enables free passage of the mitochondrial membranes to solutes of up to 1.5 kDa, and which contributes to cell death (By similarity). It is however unclear if SLC25A6/ANT3 constitutes a pore-forming component of mPTP or regulates it (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A5G2RDZ2", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0005471 ATP:ADP antiporter activity", "go_cellular_component": "GO:0005743 mitochondrial inner membrane;GO:0016020 membrane;GO:0005757 mitochondrial permeability transition pore complex", "go_biological_process": "GO:0006915 apoptotic process;GO:0046902 regulation of mitochondrial membrane permeability;GO:0140021 mitochondrial ADP transmembrane transport;GO:1990544 mitochondrial ATP transmembrane transport;GO:0055085 transmembrane transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q6QRN9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q6RHW2-1", "uniprot_id": "HYAL3_PIG", "mass": 46393.0, "length": 419, "protein_name": "Hyaluronidase-3", "gene_name": "HYAL3", "organism": "Pig", "refseq_name": "hyaluronidase-3 precursor", "refseq_ac": "NP_999604", "gene_names_uniprotkb": "HYAL3", "gene_names_refseq": "HYAL3", "protein_names_uniprotkb": "Hyaluronidase-3; 3.2.1.35; Hyal-3; Hyaluronoglucosaminidase-3", "protein_names_refseq": "hyal-3; hyaluronidase-3 precursor; hyaluronoglucosaminidase 3", "tax_id": 9823, "disease": "", "pathway": " (ssc:404696)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "14619892;15218248", "class_list": "", "function": "Facilitates sperm penetration into the layer of cumulus cells surrounding the egg by digesting hyaluronic acid. Involved in induction of the acrosome reaction in the sperm. Involved in follicular atresia, the breakdown of immature ovarian follicles that are not selected to ovulate. Induces ovarian granulosa cell apoptosis, possibly via apoptotic signaling pathway involving CASP8 and CASP3 activation, and poly(ADP-ribose) polymerase (PARP) cleavage. Has no hyaluronidase activity in embryonic fibroblasts in vitro. Has no hyaluronidase activity in granulosa cells in vitro., [UniProtKB, UniProtKB]; The porcine hyaluronidase cluster consisting of genes HYAL1, HYAL2 and HYAL3 was characterized Erratum:[Cytogenet Genome Res. 2005;109(4):535], [RefSeq, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "Q6S3P5", "ec_number_list": "", "go_molecular_function": "GO:0004415 hyalurononglucosaminidase activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0005769 early endosome;GO:0005783 endoplasmic reticulum;GO:0005886 plasma membrane;GO:0031410 cytoplasmic vesicle", "go_biological_process": "GO:2000355 negative regulation of ovarian follicle development;GO:0005975 carbohydrate metabolic process;GO:0007341 penetration of zona pellucida;GO:2000368 positive regulation of acrosomal vesicle exocytosis;GO:0030214 hyaluronan catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q6RHW2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q6RI85-1", "uniprot_id": "PGK2_PIG", "mass": 44895.0, "length": 417, "protein_name": "Phosphoglycerate kinase 2", "gene_name": "PGK2", "organism": "Pig", "refseq_name": "phosphoglycerate kinase 2", "refseq_ac": "NP_998947", "gene_names_uniprotkb": "PGK2", "gene_names_refseq": "PGK2", "protein_names_uniprotkb": "Phosphoglycerate kinase 2; 2.7.2.3; Phosphoglycerate kinase, testis specific", "protein_names_refseq": "phosphoglycerate kinase 2; phosphoglycerate kinase, testis specific; testis-specific phosphoglycerate kinase 2", "tax_id": 9823, "disease": "", "pathway": " (ssc:396673); (R-SSC-70171); (R-SSC-70263)", "pathway_count": 3, "publication_count": 2, "publication_id_list": "15599558;29407897", "class_list": "", "function": "Catalyzes the reversible conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate and plays a role in glycolysis and gluconeogenesis. Essential for sperm motility and male fertility but not required for the completion of spermatogenesis., [UniProtKB, UniProtKB]; PGK2 is expressed differently in the testes of mouse and pigs according to developmental stage., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q6RFZ5", "ec_number_list": "", "go_molecular_function": "GO:0004618 phosphoglycerate kinase activity;GO:0005524 ATP binding;GO:0046872 metal ion binding;GO:0043531 ADP binding", "go_cellular_component": "GO:0005829 cytosol;GO:0035686 sperm fibrous sheath", "go_biological_process": "GO:0006094 gluconeogenesis;GO:0006096 glycolytic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q6RI85-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q6S4N2-1", "uniprot_id": "HS71B_PIG", "mass": 70098.0, "length": 641, "protein_name": "Heat shock 70 kDa protein 1B", "gene_name": "HSP70.2; HSPA1B", "organism": "Pig", "refseq_name": "heat shock 70 kDa protein 1B", "refseq_ac": "NP_998931", "gene_names_uniprotkb": "HSP70.2; HSPA1B", "gene_names_refseq": "HSP70.2; HSPA1A; HSPA1B", "protein_names_uniprotkb": "Heat shock 70 kDa protein 1B; HSP70.2; Heat shock 70 kDa protein 2", "protein_names_refseq": "heat shock 70 kDa protein 1B; heat shock 70 kDa protein 2; heat shock 70kDa protein 1A; heat shock 70kDa protein 1B", "tax_id": 9823, "disease": "", "pathway": " (ssc:396648); (R-SSC-3371453); (R-SSC-3371497); (R-SSC-3371568); (R-SSC-3371571); (R-SSC-450408); (R-SSC-6798695); (R-SSC-9833482); (R-SSC-9841251)", "pathway_count": 9, "publication_count": 2, "publication_id_list": "16627676;32543654", "class_list": "", "function": "Molecular chaperone implicated in a wide variety of cellular processes, including protection of the proteome from stress, folding and transport of newly synthesized polypeptides, activation of proteolysis of misfolded proteins and the formation and dissociation of protein complexes. Plays a pivotal role in the protein quality control system, ensuring the correct folding of proteins, the re-folding of misfolded proteins and controlling the targeting of proteins for subsequent degradation. This is achieved through cycles of ATP binding, ATP hydrolysis and ADP release, mediated by co-chaperones. The co-chaperones have been shown to not only regulate different steps of the ATPase cycle, but they also have an individual specificity such that one co-chaperone may promote folding of a substrate while another may promote degradation. The affinity for polypeptides is regulated by its nucleotide bound state. In the ATP-bound form, it has a low affinity for substrate proteins. However, upon hydrolysis of the ATP to ADP, it undergoes a conformational change that increases its affinity for substrate proteins. It goes through repeated cycles of ATP hydrolysis and nucleotide exchange, which permits cycles of substrate binding and release. The co-chaperones are of three types: J-domain co-chaperones such as HSP40s (stimulate ATPase hydrolysis by HSP70), the nucleotide exchange factors (NEF) such as BAG1/2/3 (facilitate conversion of HSP70 from the ADP-bound to the ATP-bound state thereby promoting substrate release), and the TPR domain chaperones such as HOPX and STUB1. Maintains protein homeostasis during cellular stress through two opposing mechanisms: protein refolding and degradation. Its acetylation/deacetylation state determines whether it functions in protein refolding or protein degradation by controlling the competitive binding of co-chaperones HOPX and STUB1. During the early stress response, the acetylated form binds to HOPX which assists in chaperone-mediated protein refolding, thereafter, it is deacetylated and binds to ubiquitin ligase STUB1 that promotes ubiquitin-mediated protein degradation. Regulates centrosome integrity during mitosis, and is required for the maintenance of a functional mitotic centrosome that supports the assembly of a bipolar mitotic spindle. Enhances STUB1-mediated SMAD3 ubiquitination and degradation and facilitates STUB1-mediated inhibition of TGF-beta signaling. Essential for STUB1-mediated ubiquitination and degradation of FOXP3 in regulatory T-cells (Treg) during inflammation., [UniProtKB, UniProtKB]; Overexpression of the HSP70.2 gene in multiple organs of transgenic mice improves survival during heatstroke by reducing hyperthermia, circulatory shock, and cerebral ischemia and damage, [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0016887 ATP hydrolysis activity;GO:0031072 heat shock protein binding;GO:0044183 protein folding chaperone", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005813 centrosome;GO:0005829 cytosol;GO:0005886 plasma membrane", "go_biological_process": "GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process;GO:0042026 protein refolding;GO:1901673 regulation of mitotic spindle assembly;GO:0090063 positive regulation of microtubule nucleation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q6S4N2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q6UGB2-1", "uniprot_id": "MSMO1_PIG", "mass": 35102.0, "length": 293, "protein_name": "Methylsterol monooxygenase 1", "gene_name": "MSMO1", "organism": "Pig", "refseq_name": "methylsterol monooxygenase 1", "refseq_ac": "NP_998917", "gene_names_uniprotkb": "MSMO1; SC4MOL", "gene_names_refseq": "MSMO1; SC4MOL", "protein_names_uniprotkb": "Methylsterol monooxygenase 1; 1.14.18.9; C-4 methylsterol oxidase; Sterol-C4-methyl oxidase", "protein_names_refseq": "C-4 methylsterol oxidase; methylsterol monooxygenase 1; sterol-C4-methyl oxidase-like protein", "tax_id": 9823, "disease": "", "pathway": " (ssc:396590)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Catalyzes the three-step monooxygenation required for the demethylation of 4,4-dimethyl and 4alpha-methylsterols, which can be subsequently metabolized to cholesterol., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0000254 C-4 methylsterol oxidase activity;GO:0005506 iron ion binding", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0016126 sterol biosynthetic process;GO:0006695 cholesterol biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q6UGB2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q6VFT6-1", "uniprot_id": "FOXL2_PIG", "mass": 38918.0, "length": 377, "protein_name": "Forkhead box protein L2", "gene_name": "FOXL2", "organism": "Pig", "refseq_name": "forkhead box protein L2", "refseq_ac": "NP_001231594", "gene_names_uniprotkb": "FOXL2", "gene_names_refseq": "FOXL2", "protein_names_uniprotkb": "Forkhead box protein L2", "protein_names_refseq": "forkhead box protein L2; forkhead transcription factor L2", "tax_id": 9823, "disease": "", "pathway": " (ssc:100622956); (R-SSC-3232118)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "14684984", "class_list": "", "function": "Transcriptional regulator. Critical factor essential for ovary differentiation and maintenance, and repression of the genetic program for somatic testis determination (By similarity). Prevents trans-differentiation of ovary to testis through transcriptional repression of the Sertoli cell-promoting gene SOX9 (By similarity). Has apoptotic activity in ovarian cells (By similarity). Suppresses ESR1-mediated transcription of PTGS2/COX2 stimulated by tamoxifen (By similarity). Activates SIRT1 transcription under cellular stress conditions (By similarity). Activates transcription of OSR2 (By similarity). Is a regulator of CYP19 expression (By similarity). Is a transcriptional repressor of STAR (By similarity). Participates in SMAD3-dependent transcription of FST via the intronic SMAD-binding element (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0003700 DNA-binding transcription factor activity;GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding;GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific;GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process", "go_cellular_component": "GO:0005634 nucleus", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0030154 cell differentiation;GO:0043065 positive regulation of apoptotic process;GO:0045944 positive regulation of transcription by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q6VFT6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q6ZYM3-1", "uniprot_id": "ASIP_PIG", "mass": 14498.0, "length": 131, "protein_name": "Agouti-signaling protein", "gene_name": "ASIP", "organism": "Pig", "refseq_name": "agouti-signaling protein isoform 1A precursor", "refseq_ac": "NP_001001648", "gene_names_uniprotkb": "ASIP", "gene_names_refseq": "ASIP; agouti", "protein_names_uniprotkb": "Agouti-signaling protein; ASP; Agouti switch protein", "protein_names_refseq": "ASP; agouti signaling protein, nonagouti homolog; agouti signalling protein; agouti singaling protein; agouti switch protein; agouti-signaling protein isoform 1A precursor", "tax_id": 9823, "disease": "", "pathway": " (ssc:414439)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "11105218;16416091;16734703", "class_list": "", "function": "Involved in the regulation of melanogenesis. The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment) (By similarity)., [UniProtKB, UniProtKB]; Mutational analysis of the ASIP loci in relation to coat color., [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q4R1H8;Q5QJU6", "ec_number_list": "", "go_molecular_function": "GO:0048019 receptor antagonist activity;GO:0005184 neuropeptide hormone activity;GO:0070996 type 1 melanocortin receptor binding;GO:0031779 melanocortin receptor binding", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0048022 negative regulation of melanin biosynthetic process;GO:0009755 hormone-mediated signaling pathway;GO:0032438 melanosome organization;GO:0042438 melanin biosynthetic process;GO:0048023 positive regulation of melanin biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q6ZYM3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q710C4-1", "uniprot_id": "SAHH_PIG", "mass": 47694.0, "length": 432, "protein_name": "Adenosylhomocysteinase", "gene_name": "AHCY", "organism": "Pig", "refseq_name": "adenosylhomocysteinase", "refseq_ac": "NP_001011727", "gene_names_uniprotkb": "AHCY", "gene_names_refseq": "AHCY", "protein_names_uniprotkb": "Adenosylhomocysteinase; 3.13.2.1; AdoHcyase; S-adenosyl-L-homocysteine hydrolase", "protein_names_refseq": "S-adenosyl-L-homocysteine hydrolase; S-adenosylhomocysteine hydrolase; adenosylhomocysteinase; adoHcyase", "tax_id": 9823, "disease": "", "pathway": " (ssc:497050)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "12438749", "class_list": "", "function": "Catalyzes the hydrolysis of S-adenosyl-L-homocysteine to form adenosine and homocysteine (By similarity). Binds copper ions (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q4R1H7", "ec_number_list": "", "go_molecular_function": "GO:0051287 NAD binding;GO:0004013 adenosylhomocysteinase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005783 endoplasmic reticulum;GO:0005829 cytosol;GO:0042470 melanosome", "go_biological_process": "GO:0006730 one-carbon metabolic process;GO:0033353 S-adenosylmethionine cycle", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q710C4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q712U6-1", "uniprot_id": "ARP19_PIG", "mass": 12323.0, "length": 112, "protein_name": "cAMP-regulated phosphoprotein 19", "gene_name": "ARPP19", "organism": "Pig", "refseq_name": "cAMP-regulated phosphoprotein 19", "refseq_ac": "NP_999340", "gene_names_uniprotkb": "ARPP19", "gene_names_refseq": "ARPP-19; ARPP19", "protein_names_uniprotkb": "cAMP-regulated phosphoprotein 19; ARPP-19", "protein_names_refseq": "cAMP-regulated phosphoprotein 19", "tax_id": 9823, "disease": "", "pathway": " (ssc:397362); (R-SSC-2465910)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "10875629;16484796", "class_list": "", "function": "Chromosome mapping in pigs, [RefSeq, PubMed]; Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis (By similarity). Inhibition of PP2A is enhanced when ARPP19 is phosphorylated (By similarity). When phosphorylated at Ser-62 during mitosis, specifically interacts with PPP2R2D (PR55-delta) and inhibits its activity, leading to inactivation of PP2A, an essential condition to keep cyclin-B1-CDK1 activity high during M phase (By similarity). May indirectly enhance GAP-43 expression by binding to the NGF-regulatory region of its mRNA (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005102 signaling receptor binding;GO:0015459 potassium channel regulator activity;GO:0019888 protein phosphatase regulator activity;GO:0051721 protein phosphatase 2A binding;GO:0019212 phosphatase inhibitor activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0000278 mitotic cell cycle;GO:0051301 cell division;GO:0000086 G2/M transition of mitotic cell cycle;GO:0045722 positive regulation of gluconeogenesis", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q712U6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q764M8-1", "uniprot_id": "INAR1_PIG", "mass": 63221.0, "length": 560, "protein_name": "Interferon alpha/beta receptor 1", "gene_name": "IFNAR1", "organism": "Pig", "refseq_name": "interferon alpha/beta receptor 1 isoform 1 precursor", "refseq_ac": "NP_998937", "gene_names_uniprotkb": "IFNAR1", "gene_names_refseq": "IFN-R-1; IFNAR1", "protein_names_uniprotkb": "Interferon alpha/beta receptor 1; IFN-R-1; IFN-alpha/beta receptor 1; Type I interferon receptor 1", "protein_names_refseq": "IFN-alpha/beta receptor 1; interferon (alpha, beta and omega) receptor 1; interferon alpha/beta receptor 1 isoform 1 precursor; interferon alpha/beta receptor 1; type I interferon receptor 1", "tax_id": 9823, "disease": "", "pathway": " (ssc:396658)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "14681463;17065794;27769575", "class_list": "", "function": "The complete 168,835 bp insert sequence of a porcine BAC clone harboring the IFNAR1 gene was determined., [RefSeq, PubMed]; These results suggest that endometrial and conceptus IFNAR1 and IFNAR2 may mediate the action of type I IFNs during the implantation period for the establishment and maintenance of pregnancy in pigs., [RefSeq, PubMed]; Together with IFNAR2, forms the heterodimeric receptor for type I interferons (including interferons alpha, beta, epsilon, omega and kappa). Type I interferon binding activates the JAK-STAT signaling cascade, resulting in transcriptional activation or repression of interferon-regulated genes that encode the effectors of the interferon response. Mechanistically, type I interferon-binding brings the IFNAR1 and IFNAR2 subunits into close proximity with one another, driving their associated Janus kinases (JAKs) (TYK2 bound to IFNAR1 and JAK1 bound to IFNAR2) to cross-phosphorylate one another. The activated kinases phosphorylate specific tyrosine residues on the intracellular domains of IFNAR1 and IFNAR2, forming docking sites for the STAT transcription factors. STAT proteins are then phosphorylated by the JAKs, promoting their translocation into the nucleus to regulate expression of interferon-regulated genes (By similarity). Can also act independently of IFNAR2: form an active IFNB1 receptor by itself and activate a signaling cascade that does not involve activation of the JAK-STAT pathway (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 10, "predicted_n_glycosites": 10, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 10, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004905 type I interferon receptor activity;GO:0019962 type I interferon binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005764 lysosome;GO:0005770 late endosome", "go_biological_process": "GO:0035457 cellular response to interferon-alpha;GO:0009893 positive regulation of metabolic process;GO:0032496 response to lipopolysaccharide;GO:0060337 type I interferon-mediated signaling pathway;GO:0009615 response to virus", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q764M8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q767K7-1", "uniprot_id": "ATAT_PIG", "mass": 34073.0, "length": 300, "protein_name": "Alpha-tubulin N-acetyltransferase 1", "gene_name": "ATAT1", "organism": "Pig", "refseq_name": "alpha-tubulin N-acetyltransferase 1", "refseq_ac": "NP_001116595", "gene_names_uniprotkb": "ATAT1; MEC17", "gene_names_refseq": "ATAT1; C7H6ORF134; MEC17; TAT", "protein_names_uniprotkb": "Alpha-tubulin N-acetyltransferase 1; 2.3.1.108; Acetyltransferase mec-17 homolog; Alpha-TAT1; Alpha-TAT; TAT", "protein_names_refseq": "acetyltransferase mec-17 homolog; alpha-TAT1; alpha-TAT; alpha-tubulin N-acetyltransferase 1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100144480)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "14673549", "class_list": "", "function": "Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dynamically unstable microtubules before the enzyme is released. Required for normal sperm flagellar function. Promotes directional cell locomotion and chemotaxis, through AP2A2-dependent acetylation of alpha-tubulin at clathrin-coated pits that are concentrated at the leading edge of migrating cells. May facilitate primary cilium assembly., [UniProtKB, HAMAP]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004468 L-lysine N-acetyltransferase activity, acting on acetyl phosphate as donor;GO:0019799 tubulin N-acetyltransferase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005819 spindle;GO:0005874 microtubule;GO:0005905 clathrin-coated pit;GO:0005925 focal adhesion", "go_biological_process": "GO:0000226 microtubule cytoskeleton organization;GO:0048666 neuron development;GO:0070507 regulation of microtubule cytoskeleton organization;GO:0071929 alpha-tubulin acetylation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q767K7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q767K9-1", "uniprot_id": "PP1RA_PIG", "mass": 97596.0, "length": 925, "protein_name": "Serine/threonine-protein phosphatase 1 regulatory subunit 10", "gene_name": "PPP1R10", "organism": "Pig", "refseq_name": "serine/threonine-protein phosphatase 1 regulatory subunit 10", "refseq_ac": "NP_001116637", "gene_names_uniprotkb": "PPP1R10; CAT53; FB19", "gene_names_refseq": "CAT53; FB19; PPP1R10", "protein_names_uniprotkb": "Serine/threonine-protein phosphatase 1 regulatory subunit 10; MHC class I region proline-rich protein CAT53; Protein FB19", "protein_names_refseq": "MHC class I region proline-rich protein CAT53; protein phosphatase 1, regulatory (inhibitor) subunit 10; serine/threonine-protein phosphatase 1 regulatory subunit 10", "tax_id": 9823, "disease": "", "pathway": " (ssc:100144450)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "14673549;32543654", "class_list": "", "function": "Substrate-recognition component of the PNUTS-PP1 protein phosphatase complex, a protein phosphatase 1 (PP1) complex that promotes RNA polymerase II transcription pause-release, allowing transcription elongation. Promoter-proximal pausing by RNA polymerase II is a transcription halt following transcription initiation but prior to elongation, which acts as a checkpoint to control that transcripts are favorably configured for transcriptional elongation. The PNUTS-PP1 complex mediates the release of RNA polymerase II from promoter-proximal region of genes by catalyzing dephosphorylation of proteins involved in transcription, such as AFF4, CDK9, MEPCE, INTS12, NCBP1, POLR2M/GDOWN1 and SUPT6H. The PNUTS-PP1 complex also regulates RNA polymerase II transcription termination by mediating dephosphorylation of SUPT5H in termination zones downstream of poly(A) sites, thereby promoting deceleration of RNA polymerase II transcription. PNUTS-PP1 complex is also involved in the response to replication stress by mediating dephosphorylation of POLR2A at 'Ser-5' of the CTD, promoting RNA polymerase II degradation (By similarity). The PNUTS-PP1 complex also plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase (By similarity). PNUTS-PP1 complex mediates dephosphorylation of MYC, promoting MYC stability by preventing MYC ubiquitination by the SCF(FBXW7) complex. In addition to acts as a substrate-recognition component, PPP1R10/PNUTS also acts as a nuclear targeting subunit for the PNUTS-PP1 complex. In some context, PPP1R10/PNUTS also acts as an inhibitor of protein phosphatase 1 (PP1) activity by preventing access to substrates, such as RB (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0003723 RNA binding;GO:0008270 zinc ion binding;GO:0019888 protein phosphatase regulator activity;GO:0008157 protein phosphatase 1 binding", "go_cellular_component": "GO:0005634 nucleus;GO:0000785 chromatin;GO:0072357 PTW/PP1 phosphatase complex", "go_biological_process": "GO:2000806 positive regulation of termination of RNA polymerase II transcription, poly(A)-coupled;GO:0001111 RNA polymerase II promoter clearance;GO:0032968 positive regulation of transcription elongation by RNA polymerase II;GO:0034244 negative regulation of transcription elongation by RNA polymerase II", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q767K9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q7M329-1", "uniprot_id": "RNT2_PIG", "mass": 23136.0, "length": 200, "protein_name": "Ribonuclease T2", "gene_name": "RNASET2", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "RNASET2", "gene_names_refseq": "", "protein_names_uniprotkb": "Ribonuclease T2; 4.6.1.19", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "9657053", "class_list": "", "function": "Ribonuclease that plays an essential role in innate immune response by recognizing and degrading RNAs from microbial pathogens that are subsequently sensed by TLR8. Cleaves preferentially single-stranded RNA molecules between purine and uridine residues, which critically contributes to the supply of catabolic uridine and the generation of purine-2',3'-cyclophosphate-terminated oligoribonucleotides. In turn, RNase T2 degradation products promote the RNA-dependent activation of TLR8. In plasmacytoid dendritic cells, it cooperates with PLD3 or PLD4 5'->3' exonucleases to process RNA fragments and release 2',3'-cyclic guanosine monophosphate (2',3'-cGMP), a potent stimulatory ligand for TLR7. Also plays a key role in degradation of mitochondrial RNA and processing of non-coding RNA imported from the cytosol into mitochondria. Participates as well in degradation of mitochondrion-associated cytosolic rRNAs., [UniProtKB, UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding;GO:0016787 hydrolase activity;GO:0004540 RNA nuclease activity;GO:0004521 RNA endonuclease activity;GO:0033897 ribonuclease T2 activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0005615 extracellular space;GO:0005758 mitochondrial intermembrane space;GO:0005788 endoplasmic reticulum lumen;GO:0005764 lysosome", "go_biological_process": "GO:0045087 innate immune response;GO:0006401 RNA catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q7M329-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q7YR83-1", "uniprot_id": "ESPB1_PIG", "mass": 26200.0, "length": 223, "protein_name": "Epididymal sperm-binding protein 1", "gene_name": "ELSPBP1", "organism": "Pig", "refseq_name": "epididymal sperm-binding protein 1 precursor", "refseq_ac": "NP_999569", "gene_names_uniprotkb": "ELSPBP1; E12", "gene_names_refseq": "E12; ELSPBP1", "protein_names_uniprotkb": "Epididymal sperm-binding protein 1; Epididymal secretory protein 12", "protein_names_refseq": "epididymal secretory protein 12; epididymal sperm-binding protein 1 precursor", "tax_id": 9823, "disease": "", "pathway": " (ssc:399529)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "17307309", "class_list": "", "function": "Binds to spermatozoa upon ejaculation and may play a role in sperm capacitation. Has phosphorylcholine-binding activity., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q7YR82", "ec_number_list": "", "go_molecular_function": "GO:0008201 heparin binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0009986 cell surface", "go_biological_process": "GO:0033700 phospholipid efflux;GO:0007338 single fertilization;GO:0048240 sperm capacitation;GO:1902492 positive regulation of sperm capacitation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q7YR83-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q7YRB2-1", "uniprot_id": "CP8B1_PIG", "mass": 57772.0, "length": 501, "protein_name": "5-beta-cholestane-3-alpha,7-alpha-diol 12-alpha-hydroxylase", "gene_name": "CYP8B1", "organism": "Pig", "refseq_name": "5-beta-cholestane-3-alpha,7-alpha-diol 12-alpha-hydroxylase", "refseq_ac": "NP_999591", "gene_names_uniprotkb": "CYP8B1", "gene_names_refseq": "CYP8B1", "protein_names_uniprotkb": "5-beta-cholestane-3-alpha,7-alpha-diol 12-alpha-hydroxylase; 1.14.14.139; CYPVIIIB1; Cytochrome P450 8B1; Sterol 12-alpha-hydroxylase", "protein_names_refseq": "5-beta-cholestane-3-alpha,7-alpha-diol 12-alpha-hydroxylase; CYPVIIIB1; cytochrome P-450 8B1; cytochrome P450 8B1; sterol 12-alpha-hydroxylase; sterol 12alpha-hydroxylase", "tax_id": 9823, "disease": "", "pathway": " (ssc:403328)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "14643796", "class_list": "", "function": "Sterol 12-alpha-hydroxylase involved in primary bile acid biosynthesis by catalyzing the 12alpha-hydroxylation of key intermediates including 7alpha-hydroxycholest-4-en-3-one, 3alpha,7alpha-dihydroxy-5beta-cholestan-26-oate and chenodeoxycholate along the classic pathway (PubMed:14643796). May also hydroxylate 5beta-cholestane-3alpha,7alpha-diol. Functions as a monooxygenase, inserting one atom of molecular oxygen into substrates while reducing the second to water, using electrons supplied by NADPH via cytochrome P450 reductase (CPR) (By similarity). Controls biliary balance of cholic acid and chenodeoxycholic acid, thereby regulating intestinal absorption of dietary lipids (By similarity)., [UniProtKB, UniProtKB, PubMed, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008397 sterol 12-alpha-hydroxylase activity;GO:0005506 iron ion binding;GO:0020037 heme binding", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006699 bile acid biosynthetic process;GO:0006694 steroid biosynthetic process;GO:0045797 positive regulation of intestinal cholesterol absorption", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q7YRB2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q7YRU3-1", "uniprot_id": "PLCZ1_PIG", "mass": 73702.0, "length": 636, "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1", "gene_name": "PLCZ", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "PLCZ", "gene_names_refseq": "", "protein_names_uniprotkb": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1; 3.1.4.11; PLC-zeta-1; Phosphoinositide phospholipase C-zeta-1; Phospholipase C-zeta-1", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (ssc:397632)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "16098961;16940280", "class_list": "", "function": "The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. In vitro, hydrolyzes PtdIns(4,5)P2 in a Ca(2+)-dependent manner. Triggers intracellular Ca(2+) oscillations in oocytes solely during M phase and is involved in inducing oocyte activation and initiating embryonic development up to the blastocyst stage. Is therefore a strong candidate for the egg-activating soluble sperm factor that is transferred from the sperm into the egg cytoplasm following gamete membrane fusion. May exert an inhibitory effect on phospholipase-C-coupled processes that depend on calcium ions and protein kinase C, including CFTR trafficking and function., [UniProtKB, UniProtKB, PubMed, UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004435 phosphatidylinositol-4,5-bisphosphate phospholipase C activity", "go_cellular_component": "GO:0005634 nucleus;GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "GO:0035556 intracellular signal transduction;GO:0016042 lipid catabolic process;GO:0007343 egg activation;GO:0060470 positive regulation of cytosolic calcium ion concentration involved in egg activation", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q7YRU3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q7YRV6-1", "uniprot_id": "SOCS2_PIG", "mass": 22254.0, "length": 198, "protein_name": "Suppressor of cytokine signaling 2", "gene_name": "SOCS2", "organism": "Pig", "refseq_name": "suppressor of cytokine signaling 2", "refseq_ac": "NP_001090930", "gene_names_uniprotkb": "SOCS2", "gene_names_refseq": "SOCS2", "protein_names_uniprotkb": "Suppressor of cytokine signaling 2; SOCS-2", "protein_names_refseq": "SOCS-2; suppressor of cytokine signaling 2; suppressor of cytokine signalling 2", "tax_id": 9823, "disease": "", "pathway": " (ssc:100037966); (R-SSC-8951664); (R-SSC-9706369)", "pathway_count": 3, "publication_count": 2, "publication_id_list": "16097082;20045027", "class_list": "", "function": "Mapping of this negative regulator of cytokine-induced signal transduction, [RefSeq, PubMed]; Substrate-recognition component of a cullin-5-RING E3 ubiquitin-protein ligase complex (ECS complex, also named CRL5 complex), which mediates the ubiquitination and subsequent proteasomal degradation of target proteins, such as EPOR and GHR. Specifically recognizes and binds phosphorylated proteins via its SH2 domain, promoting their ubiquitination. The ECS(SOCS2) complex acts as a key regulator of growth hormone receptor (GHR) levels by mediating ubiquitination and degradation of GHR, following GHR phosphorylation by JAK2. The ECS(SOCS2) also catalyzes ubiquitination and degradation of JAK2-phosphorylated EPOR., [UniProtKB, UniProtKB]; Upregulated in intestinal epithelium in response to parasitic infections, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005159 insulin-like growth factor receptor binding;GO:1990756 ubiquitin-like ligase-substrate adaptor activity;GO:0005131 growth hormone receptor binding;GO:0140031 phosphorylation-dependent protein binding;GO:0005126 cytokine receptor binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0031466 Cul5-RING ubiquitin ligase complex", "go_biological_process": "GO:0060400 negative regulation of growth hormone receptor signaling pathway;GO:0035556 intracellular signal transduction;GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process;GO:0032355 response to estradiol;GO:0016567 protein ubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q7YRV6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q7YS88-1", "uniprot_id": "RAMP3_PIG", "mass": 17368.0, "length": 151, "protein_name": "Receptor activity-modifying protein 3", "gene_name": "RAMP3", "organism": "Pig", "refseq_name": "receptor activity-modifying protein 3 precursor", "refseq_ac": "NP_999254", "gene_names_uniprotkb": "RAMP3", "gene_names_refseq": "RAMP3", "protein_names_uniprotkb": "Receptor activity-modifying protein 3", "protein_names_refseq": "receptor activity-modifying protein 3 precursor", "tax_id": 9823, "disease": "", "pathway": " (ssc:397163)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "12759187", "class_list": "", "function": "Accessory protein that interacts with and modulates the function of G protein-coupled receptors including calcitonin gene-related peptide type 1 receptor (CALCRL), calcitonin receptor (CALCR) and G protein-coupled estrogen receptor 1 (GPER1). Required for the transport of CALCRL and GPER1 receptors to the plasma membrane. Plays a role in cardioprotection by reducing cardiac hypertrophy and perivascular fibrosis in a GPER1-dependent manner. Together with CALCRL, form a receptor complex for adrenomedullin/ADM and intermedin/ADM2. Together with CALCR, act as a receptor complex for amylin/IAPP., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "Q7YS89;Q867B8", "ec_number_list": "", "go_molecular_function": "GO:0015026 coreceptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0009986 cell surface;GO:0043235 receptor complex", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0007186 G protein-coupled receptor signaling pathway;GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0015031 protein transport;GO:0031623 receptor internalization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q7YS88-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q863I2-1", "uniprot_id": "OXSR1_PIG", "mass": 58233.0, "length": 529, "protein_name": "Serine/threonine-protein kinase OSR1", "gene_name": "OXSR1", "organism": "Pig", "refseq_name": "serine/threonine-protein kinase OSR1", "refseq_ac": "NP_999507", "gene_names_uniprotkb": "OXSR1; OSR1", "gene_names_refseq": "OXSR1", "protein_names_uniprotkb": "Serine/threonine-protein kinase OSR1; 2.7.11.1; Oxidative stress-responsive 1 protein", "protein_names_refseq": "oxidative stress responsive 1; oxidative stress-responsive 1 protein; serine/threonine-protein kinase OSR1", "tax_id": 9823, "disease": "", "pathway": " (ssc:397618)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15561286", "class_list": "", "function": "Effector serine/threonine-protein kinase component of the WNK-SPAK/OSR1 kinase cascade, which is involved in various processes, such as ion transport, response to hypertonic stress and blood pressure (By similarity). Specifically recognizes and binds proteins with a RFXV motif (By similarity). Acts downstream of WNK kinases (WNK1, WNK2, WNK3 or WNK4): following activation by WNK kinases, catalyzes phosphorylation of ion cotransporters, such as SLC12A1/NKCC2, SLC12A2/NKCC1, SLC12A3/NCC, SLC12A5/KCC2 or SLC12A6/KCC3, regulating their activity (By similarity). Mediates regulatory volume increase in response to hyperosmotic stress by catalyzing phosphorylation of ion cotransporters SLC12A1/NKCC2, SLC12A2/NKCC1 and SLC12A6/KCC3 downstream of WNK1 and WNK3 kinases (By similarity). Phosphorylation of Na-K-Cl cotransporters SLC12A2/NKCC1 and SLC12A2/NKCC1 promote their activation and ion influx; simultaneously, phosphorylation of K-Cl cotransporters SLC12A5/KCC2 and SLC12A6/KCC3 inhibit their activity, blocking ion efflux (By similarity). Acts as a regulator of NaCl reabsorption in the distal nephron by mediating phosphorylation and activation of the thiazide-sensitive Na-Cl cotransporter SLC12A3/NCC in distal convoluted tubule cells of kidney downstream of WNK4 (By similarity). Also acts as a regulator of angiogenesis in endothelial cells downstream of WNK1 (By similarity). Acts as an activator of inward rectifier potassium channels KCNJ2/Kir2.1 and KCNJ4/Kir2.3 downstream of WNK1: recognizes and binds the RXFXV/I variant motif on KCNJ2/Kir2.1 and KCNJ4/Kir2.3 and regulates their localization to the cell membrane without mediating their phosphorylation (By similarity). Phosphorylates RELL1, RELL2, RELT and PAK1. Phosphorylates PLSCR1 in the presence of RELT (By similarity)., [UniProtKB, UniProtKB, UniProtKB]; The gene shows 92.8% nucleotide identity and 95.5% amino acid identity with human OSR1., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 8, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol", "go_biological_process": "GO:0006468 protein phosphorylation;GO:0010820 positive regulation of T cell chemotaxis;GO:0035556 intracellular signal transduction;GO:0046777 protein autophosphorylation;GO:0071474 cellular hyperosmotic response", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q863I2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q863Z5-1", "uniprot_id": "IL4RA_PIG", "mass": 89441.0, "length": 830, "protein_name": "Interleukin-4 receptor subunit alpha", "gene_name": "IL4R", "organism": "Pig", "refseq_name": "interleukin-4 receptor subunit alpha precursor", "refseq_ac": "NP_999505", "gene_names_uniprotkb": "IL4R", "gene_names_refseq": "IL4R; IL4", "protein_names_uniprotkb": "Interleukin-4 receptor subunit alpha; IL-4 receptor subunit alpha; IL-4R subunit alpha; IL-4R-alpha; IL-4RA", "protein_names_refseq": "IL-4 receptor subunit alpha; IL-4R subunit alpha; IL-4R-alpha; IL-4RA; interleukin 4 receptor alpha; interleukin 4 tv3; interleukin 4 tv5; interleukin-4 receptor subunit alpha precursor; interleukin-4 receptor subunit alpha", "tax_id": 9823, "disease": "", "pathway": " (ssc:397614)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammation. In certain cell types, can signal through activation of insulin receptor substrates, IRS1/IRS2 (By similarity)., [UniProtKB]", "predicted_glycosites": 8, "predicted_n_glycosites": 7, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 8, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004913 interleukin-4 receptor activity", "go_cellular_component": "GO:0009897 external side of plasma membrane", "go_biological_process": "GO:0035771 interleukin-4-mediated signaling pathway;GO:0002532 production of molecular mediator involved in inflammatory response", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q863Z5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q864R5-1", "uniprot_id": "MIRO2_PIG", "mass": 67619.0, "length": 620, "protein_name": "Mitochondrial Rho GTPase 2", "gene_name": "RHOT2", "organism": "Pig", "refseq_name": "mitochondrial Rho GTPase 2", "refseq_ac": "NP_999490", "gene_names_uniprotkb": "RHOT2; ARHT2", "gene_names_refseq": "ARHT2; RHOT2", "protein_names_uniprotkb": "Mitochondrial Rho GTPase 2; 3.6.5.-; MIRO-2; Ras homolog gene family member T2", "protein_names_refseq": "MIRO-2; mitochondrial Rho GTPase 2; ras homolog gene family, member T2; rho GTPase", "tax_id": 9823, "disease": "", "pathway": " (ssc:397596)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "15218247", "class_list": "", "function": "Atypical mitochondrial nucleoside-triphosphatase (NTPase) involved in mitochondrial trafficking. Probably involved in control of anterograde transport of mitochondria and their subcellular distribution. Can hydrolyze GTP, ATP and UTP (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0003924 GTPase activity;GO:0005525 GTP binding;GO:0016887 ATP hydrolysis activity;GO:0005509 calcium ion binding", "go_cellular_component": "GO:0005741 mitochondrial outer membrane", "go_biological_process": "GO:0047497 mitochondrion transport along microtubule;GO:0019725 cellular homeostasis;GO:0007005 mitochondrion organization;GO:0097345 mitochondrial outer membrane permeabilization", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q864R5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q864U6-1", "uniprot_id": "B3GL1_PIG", "mass": 39437.0, "length": 331, "protein_name": "UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1", "gene_name": "B3GALNT1", "organism": "Pig", "refseq_name": "UDP-GalNAc:beta-1, 3-N-acetylgalactosaminyltransferase 1", "refseq_ac": "NP_999516", "gene_names_uniprotkb": "B3GALNT1; B3GALT3", "gene_names_refseq": "B3GALNT1; B3GALT3", "protein_names_uniprotkb": "UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1; 2.4.1.79; Beta-1,3-GalNAc-T1; Beta-1,3-GalTase 3; Beta-1,3-galactosyltransferase 3; Beta-3-Gx-T3; Beta3Gal-T3; Beta3GalT3; Galactosylgalactosylglucosylceramide beta-D-acetyl-galactosaminyltransferase; Globoside synthase; UDP-N-acetylgalactosamine:globotriaosylceramide beta-1,3-N-acetylgalactosaminyltransferase; b3Gal-T3", "protein_names_refseq": "UDP-Gal:beta-GlcNAc beta-1,3-galactosyltransferase 3; UDP-GalNAc:beta-1, 3-N-acetylgalactosaminyltransferase 1; UDP-N-acetylgalactosamine:globotriaosylceramide beta-1,3-N-acetylgalactosaminyltransferase; b3Gal-T3; beta-1,3-GalNAc-T1; beta-1,3-GalTase 3; beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group); beta-3-Gx-T3; beta3Gal-T3; beta3GalT3; galactosylgalactosylglucosylceramide beta-D-acetyl-galactosaminyltransferase; globoside synthase", "tax_id": 9823, "disease": "", "pathway": " (ssc:397634); (R-SSC-9840309)", "pathway_count": 2, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Transfers N-acetylgalactosamine onto globotriaosylceramide. Plays a critical role in preimplantation stage embryonic development., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 5, "predicted_n_glycosites": 5, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 5, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008499 N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity;GO:0047273 galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity", "go_cellular_component": "GO:0000139 Golgi membrane", "go_biological_process": "GO:0006629 lipid metabolic process;GO:0009101 glycoprotein biosynthetic process;GO:0009312 oligosaccharide biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q864U6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q865F1-1", "uniprot_id": "MTP_PIG", "mass": 99771.0, "length": 894, "protein_name": "Microsomal triglyceride transfer protein large subunit", "gene_name": "MTTP", "organism": "Pig", "refseq_name": "microsomal triglyceride transfer protein large subunit precursor", "refseq_ac": "NP_999350", "gene_names_uniprotkb": "MTTP; MTP", "gene_names_refseq": "MTP; MTTP", "protein_names_uniprotkb": "Microsomal triglyceride transfer protein large subunit", "protein_names_refseq": "microsomal triglyceride transfer protein large subunit precursor; microsomal triglyceride transfer protein large subunit", "tax_id": 9823, "disease": "", "pathway": " (ssc:397381); (R-SSC-8866423); (R-SSC-8963888); (R-SSC-8964041)", "pathway_count": 4, "publication_count": 3, "publication_id_list": "12177174;19496770;21127258", "class_list": "", "function": "Catalyzes the transport of triglyceride, cholesteryl ester, and phospholipid between phospholipid surfaces (By similarity). Required for the assembly and secretion of plasma lipoproteins that contain apolipoprotein B (By similarity). May be involved in regulating cholesteryl ester biosynthesis in cells that produce lipoproteins (By similarity)., [UniProtKB, UniProtKB, UniProtKB]; MTTP is regulated by apo A-IV in manner to promote increased packaging of triglyceride into chylomicron core, which may be important in neonatal fat absorption., [RefSeq, PubMed]; There appears to be an interaction between the porcine MTTP genotype and the type of fat source in the pig diet, which would agree with the previous results on the biology of MTTP biology., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0046982 protein heterodimerization activity;GO:0005548 phospholipid transporter activity;GO:0008289 lipid binding;GO:1902388 ceramide 1-phosphate transfer activity;GO:1904121 phosphatidylethanolamine transfer activity", "go_cellular_component": "GO:0005783 endoplasmic reticulum;GO:0005794 Golgi apparatus;GO:0016323 basolateral plasma membrane", "go_biological_process": "GO:0042157 lipoprotein metabolic process;GO:0015914 phospholipid transport;GO:0042632 cholesterol homeostasis;GO:0009306 protein secretion;GO:0034197 triglyceride transport", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q865F1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q867B6-1", "uniprot_id": "Q867B6_PIG", "mass": 59238.0, "length": 527, "protein_name": "V(D)J recombination-activating protein 2", "gene_name": "RAG2", "organism": "Pig", "refseq_name": "V(D)J recombination-activating protein 2", "refseq_ac": "NP_001121953", "gene_names_uniprotkb": "RAG2", "gene_names_refseq": "RAG-2; RAG2", "protein_names_uniprotkb": "V(D)J recombination-activating protein 2", "protein_names_refseq": "V(D)J recombination-activating protein 2; recombination activating protein 2", "tax_id": 9823, "disease": "", "pathway": " (ssc:100151744)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "24973446;27496741;32543654", "class_list": "", "function": "Homozygous RAG1/2 knockout pigs lack mature B and T lymphocytes; recombination does not occur in the Ig heavy chain (IgH) locus of RAG1- and RAG2-deficient pigs., [RefSeq, PubMed]; Produced RAG2-knockouts via somatic cell nuclear transfer and analyzed their phenotype. The V(D)J recombination processes were confirmed as being inactivated. They consistently lacked mature T and B cells but had substantial numbers of cells considered to be T- or B-cell progenitors as well as NK cells. They also lacked thymic medulla and lymphoid aggregations in the spleen, mesenteric lymph nodes, and Peyer's patches., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A4X1SJH9", "ec_number_list": "", "go_molecular_function": "GO:0003682 chromatin binding;GO:0005546 phosphatidylinositol-4,5-bisphosphate binding;GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding;GO:0008270 zinc ion binding;GO:0043325 phosphatidylinositol-3,4-bisphosphate binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0097519 DNA recombinase complex", "go_biological_process": "GO:0002331 pre-B cell allelic exclusion;GO:0033151 V(D)J recombination", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q867B6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q8HY17-1", "uniprot_id": "REL3_PIG", "mass": 15360.0, "length": 140, "protein_name": "Relaxin-3", "gene_name": "RLN3", "organism": "Pig", "refseq_name": "relaxin-3 precursor", "refseq_ac": "NP_001039144", "gene_names_uniprotkb": "RLN3; INSL7", "gene_names_refseq": "RLN3; insl7", "protein_names_uniprotkb": "Relaxin-3; Insulin-like peptide 7; Insulin-like peptide INSL7", "protein_names_refseq": "insulin-like 7; insulin-like peptide 7; insulin-like peptide INSL7; relaxin-3 precursor", "tax_id": 9823, "disease": "", "pathway": " (ssc:503836); (R-SSC-418594); (R-SSC-444821)", "pathway_count": 3, "publication_count": 3, "publication_id_list": "12506116;12686464;14522968", "class_list": "", "function": "May play a role in neuropeptide signaling processes. Ligand for LGR7, RXFP3 and RXFP4 (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A7YKU2", "ec_number_list": "", "go_molecular_function": "GO:0001664 G protein-coupled receptor binding;GO:0005179 hormone activity", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q8HY17-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q8HYN8-1", "uniprot_id": "ACTHR_PIG", "mass": 33283.0, "length": 297, "protein_name": "Adrenocorticotropic hormone receptor", "gene_name": "MC2R", "organism": "Pig", "refseq_name": "adrenocorticotropic hormone receptor", "refseq_ac": "XP_003482080", "gene_names_uniprotkb": "MC2R", "gene_names_refseq": "ACTH-R; MC2-R; MC2R", "protein_names_uniprotkb": "Adrenocorticotropic hormone receptor; ACTH receptor; ACTH-R; Adrenocorticotropin receptor; MC2-R; Melanocortin receptor 2", "protein_names_refseq": "ACTH receptor; Adrenocorticotropin receptor; Melanocortin receptor 2; adrenocorticotropic hormone receptor; melanocortin 2 receptor (adrenocorticotropic hormone)", "tax_id": 9823, "disease": "", "pathway": " (ssc:100739231); (R-SSC-375276)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "12464015", "class_list": "", "function": "G protein-coupled receptor for corticotropin/ACTH, primarily expressed in adrenal cortex where it plays a key role in the regulation of adrenocortical function. Upon activation, couples to G(s) protein, stimulating adenylate cyclase and activating the cAMP-dependent signaling pathway, the MAPK cascade as well as the PKA pathway, leading to steroidogenic factor 1/NR5A1-mediated transcriptional activation. Activation by ACTH facilitates the release of adrenal glucocorticoids, including cortisol and corticosterone (By similarity). In addition, MC2R is required for fetal and neonatal adrenal gland development (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004930 G protein-coupled receptor activity;GO:0046872 metal ion binding;GO:0004978 corticotropin receptor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane", "go_biological_process": "GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0031948 positive regulation of glucocorticoid biosynthetic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q8HYN8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q8HZV3-1", "uniprot_id": "TFR1_PIG", "mass": 86122.0, "length": 768, "protein_name": "Transferrin receptor protein 1", "gene_name": "TFRC", "organism": "Pig", "refseq_name": "transferrin receptor protein 1", "refseq_ac": "NP_999166", "gene_names_uniprotkb": "TFRC", "gene_names_refseq": "TFRC; trfr", "protein_names_uniprotkb": "Transferrin receptor protein 1; TR; TfR1; TfR; Trfr", "protein_names_refseq": "TR; tfR1; tfR; transferrin receptor (p90, CD71); transferrin receptor protein 1", "tax_id": 9823, "disease": "", "pathway": " (ssc:397062); (R-SSC-432722); (R-SSC-8856825); (R-SSC-8856828); (R-SSC-8980692); (R-SSC-9013026); (R-SSC-9013106); (R-SSC-9013148); (R-SSC-9013149); (R-SSC-9013404); (R-SSC-9013406); (R-SSC-9013407); (R-SSC-9013408); (R-SSC-9013423); (R-SSC-917977); (R-SSC-9696270); (R-SSC-9696273)", "pathway_count": 17, "publication_count": 2, "publication_id_list": "16130451;17651325", "class_list": "", "function": "Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes (By similarity). Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). Positively regulates T and B cell proliferation through iron uptake (By similarity). Acts as a lipid sensor that regulates mitochondrial fusion by regulating activation of the JNK pathway (By similarity). When dietary levels of stearate (C18:0) are low, promotes activation of the JNK pathway, resulting in HUWE1-mediated ubiquitination and subsequent degradation of the mitofusin MFN2 and inhibition of mitochondrial fusion (By similarity). When dietary levels of stearate (C18:0) are high, TFRC stearoylation inhibits activation of the JNK pathway and thus degradation of the mitofusin MFN2 (By similarity). Mediates uptake of NICOL1 into fibroblasts where it may regulate extracellular matrix production (By similarity)., [UniProtKB, UniProtKB, UniProtKB]; Two polymorphisms are identified in a single exon aafter comparaative sequencing analysis., [RefSeq, PubMed]", "predicted_glycosites": 4, "predicted_n_glycosites": 4, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004998 transferrin receptor activity", "go_cellular_component": "GO:0055037 recycling endosome;GO:0009897 external side of plasma membrane;GO:0042470 melanosome", "go_biological_process": "GO:0031623 receptor internalization;GO:0006879 intracellular iron ion homeostasis;GO:0030890 positive regulation of B cell proliferation;GO:0042102 positive regulation of T cell proliferation;GO:0006826 iron ion transport", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q8HZV3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q8MI68-1", "uniprot_id": "MUTA_PIG", "mass": 83337.0, "length": 750, "protein_name": "Methylmalonyl-CoA mutase, mitochondrial", "gene_name": "MMUT", "organism": "Pig", "refseq_name": "methylmalonyl-CoA mutase, mitochondrial precursor", "refseq_ac": "NP_999570", "gene_names_uniprotkb": "MMUT; MUT", "gene_names_refseq": "MMUT; MUT", "protein_names_uniprotkb": "Methylmalonyl-CoA mutase, mitochondrial; 5.4.99.2; MCM; Methylmalonyl-CoA isomerase", "protein_names_refseq": "MCM; methylmalonyl Coenzyme A mutase; methylmalonyl-CoA isomerase; methylmalonyl-CoA mutase, mitochondrial precursor; methylmalonyl-CoA mutase, mitochondrial", "tax_id": 9823, "disease": "", "pathway": " (ssc:399535)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "18454807", "class_list": "", "function": "Catalyzes the reversible isomerization of methylmalonyl-CoA (MMCoA) (generated from branched-chain amino acid metabolism and degradation of dietary odd chain fatty acids and cholesterol) to succinyl-CoA (3-carboxypropionyl-CoA), a key intermediate of the tricarboxylic acid cycle., [UniProtKB, UniProtKB]; MUTm-B allele was associated with disease in a dominant pattern, while the MUTm AA genotype appeared to have a protective effect against bTB infection, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q8MI71", "ec_number_list": "", "go_molecular_function": "GO:0003924 GTPase activity;GO:0042802 identical protein binding;GO:0042803 protein homodimerization activity;GO:0046872 metal ion binding;GO:0031419 cobalamin binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005759 mitochondrial matrix", "go_biological_process": "GO:0006790 sulfur compound metabolic process;GO:0019678 propionate metabolic process, methylmalonyl pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q8MI68-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q8MJS1-1", "uniprot_id": "I12R2_PIG", "mass": 96056.0, "length": 861, "protein_name": "Interleukin-12 receptor subunit beta-2", "gene_name": "IL12RB2", "organism": "Pig", "refseq_name": "interleukin-12 receptor subunit beta-2 precursor", "refseq_ac": "NP_999262", "gene_names_uniprotkb": "IL12RB2", "gene_names_refseq": "IL12RB2", "protein_names_uniprotkb": "Interleukin-12 receptor subunit beta-2; IL-12 receptor subunit beta-2; IL-12R subunit beta-2; IL-12R-beta-2; IL-12RB2", "protein_names_refseq": "IL-12 receptor subunit beta-2; IL-12R subunit beta-2; IL-12R-beta-2; IL-12RB2; interleukin-12 receptor beta 2; interleukin-12 receptor subunit beta-2 precursor", "tax_id": 9823, "disease": "", "pathway": " (ssc:397178)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "12383645;12543551", "class_list": "", "function": "Receptor for interleukin-12. This subunit is the signaling component coupling to the JAK2/STAT4 pathway., [UniProtKB]", "predicted_glycosites": 8, "predicted_n_glycosites": 7, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 8, "binding_glycan_count": 0, "secondary_ac_list": "Q8WN24", "ec_number_list": "", "go_molecular_function": "GO:0019955 cytokine binding;GO:0004896 cytokine receptor activity", "go_cellular_component": "GO:0043235 receptor complex;GO:0009897 external side of plasma membrane", "go_biological_process": "GO:0008284 positive regulation of cell population proliferation;GO:0019221 cytokine-mediated signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q8MJS1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q8SPJ0-1", "uniprot_id": "RNS10_PIG", "mass": 23740.0, "length": 213, "protein_name": "Inactive ribonuclease-like protein 10", "gene_name": "RNASE10", "organism": "Pig", "refseq_name": "inactive ribonuclease-like protein 10 precursor", "refseq_ac": "NP_001007112", "gene_names_uniprotkb": "RNASE10", "gene_names_refseq": "RNASE10; TRAIN A", "protein_names_uniprotkb": "Inactive ribonuclease-like protein 10; Protein Train A", "protein_names_refseq": "inactive ribonuclease-like protein 10 precursor; inactive ribonuclease-like protein 10; protein Train A; putative pancreatic ribonuclease", "tax_id": 9823, "disease": "", "pathway": " (ssc:396701)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "14561640;15253924", "class_list": "", "function": "Might participate in an unknown function in the epithelial cells of this first part of the epididymis by an autocrine pathway., [RefSeq, PubMed]; Secreted proximal epididymal protein required for post-testicular sperm maturation and male fertility. May be involved in sperm adhesion to the egg zona pellucida (By similarity). Does not have ribonuclease activity., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 1, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 1, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 1, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003676 nucleic acid binding", "go_cellular_component": "GO:0005576 extracellular region", "go_biological_process": "GO:0022409 positive regulation of cell-cell adhesion;GO:0050830 defense response to Gram-positive bacterium;GO:0007338 single fertilization;GO:0034113 heterotypic cell-cell adhesion;GO:1902093 positive regulation of flagellated sperm motility", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q8SPJ0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q8SQ23-1", "uniprot_id": "TPA_PIG", "mass": 63668.0, "length": 562, "protein_name": "Tissue-type plasminogen activator", "gene_name": "PLAT", "organism": "Pig", "refseq_name": "tissue-type plasminogen activator precursor", "refseq_ac": "NP_999219", "gene_names_uniprotkb": "PLAT", "gene_names_refseq": "PLAT", "protein_names_uniprotkb": "Tissue-type plasminogen activator; 3.4.21.68; t-PA; t-plasminogen activator; tPA", "protein_names_refseq": "T-plasminogen activator; t-PA; tPA; tissue-type plasminogen activator precursor; tissue-type plasminogen activator", "tax_id": 9823, "disease": "", "pathway": " (ssc:397121); (R-SSC-186797); (R-SSC-75205)", "pathway_count": 3, "publication_count": 4, "publication_id_list": "14597973;17294140;19499190;22177313", "class_list": "", "function": "A fast beta2 agonist-mediated local release of t-PA into the coronary vasculature was demonstrated. For total t-PA, this response was characterised by a biphasic release profile, [RefSeq, PubMed]; ADP acting on the endothelial P2Y(1) M receptor may mediate release of t-PA during ischemia and post-ischemic hyperemia, an effect that may counteract some of the platelet activating effects of ADP, [RefSeq, PubMed]; Converts the abundant, but inactive, zymogen plasminogen to plasmin by hydrolyzing a single Arg-Val bond in plasminogen. By controlling plasmin-mediated proteolysis, it plays an important role in tissue remodeling and degradation, in cell migration and many other physiopathological events. During oocyte activation, plays a role in cortical granule reaction in the zona reaction, which contributes to the block to polyspermy., [UniProtKB, UniProtKB]; Mild experimental hypothermia markedly reduces ischemia-related coronary tissue plasminogen activator release, which may contribute to the cardioprotective effect of hypothermia., [RefSeq, PubMed]; The plasminogen/plasminogen activator/plasmin system is activated during gamete interaction and regulates the sperm entry into the oocyte., [RefSeq, PubMed]", "predicted_glycosites": 3, "predicted_n_glycosites": 2, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004252 serine-type endopeptidase activity", "go_cellular_component": "GO:0005615 extracellular space", "go_biological_process": "GO:0014909 smooth muscle cell migration;GO:0031639 plasminogen activation;GO:0048008 platelet-derived growth factor receptor signaling pathway;GO:0060468 prevention of polyspermy", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q8SQ23-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q8WMQ3-1", "uniprot_id": "CD9_PIG", "mass": 25201.0, "length": 226, "protein_name": "CD9 antigen", "gene_name": "CD9", "organism": "Pig", "refseq_name": "CD9 antigen", "refseq_ac": "NP_999171", "gene_names_uniprotkb": "CD9", "gene_names_refseq": "CD9", "protein_names_uniprotkb": "CD9 antigen", "protein_names_refseq": "CD9 antigen", "tax_id": 9823, "disease": "", "pathway": " (ssc:397067)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "14610355;20585885;30452988", "class_list": "", "function": "Analysis of tetraspanin CD9 distribution in normal porcine tissues, [RefSeq, PubMed]; Integral membrane protein associated with integrins, which regulates different processes, such as sperm-egg fusion, platelet activation and aggregation, and cell adhesion (By similarity). Present at the cell surface of oocytes and plays a key role in sperm-egg fusion, possibly by organizing multiprotein complexes and the morphology of the membrane required for the fusion (By similarity). In myoblasts, associates with CD81 and PTGFRN and inhibits myotube fusion during muscle regeneration (By similarity). In macrophages, associates with CD81 and beta-1 and beta-2 integrins, and prevents macrophage fusion into multinucleated giant cells specialized in ingesting complement-opsonized large particles (By similarity). Also prevents the fusion between mononuclear cell progenitors into osteoclasts in charge of bone resorption (By similarity). Acts as a receptor for PSG17 (By similarity). Involved in platelet activation and aggregation (By similarity). Regulates paranodal junction formation (By similarity). Involved in cell adhesion, cell motility and tumor metastasis (By similarity)., [UniProtKB, UniProtKB, UniProtKB]; The aim of this study was to compare the localization of CD9 and CD81 tetraspanins during oocyte maturation and early development of the embryos in bovine and porcine model., [RefSeq, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005178 integrin binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0016020 membrane;GO:0070062 extracellular exosome", "go_biological_process": "GO:0035036 sperm-egg recognition;GO:0007155 cell adhesion;GO:0007342 fusion of sperm to egg plasma membrane involved in single fertilization;GO:0031623 receptor internalization;GO:0007338 single fertilization", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q8WMQ3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q8WN98-1", "uniprot_id": "MIOX_PIG", "mass": 32653.0, "length": 282, "protein_name": "Inositol oxygenase", "gene_name": "MIOX", "organism": "Pig", "refseq_name": "inositol oxygenase", "refseq_ac": "NP_999267", "gene_names_uniprotkb": "MIOX; ALDRL6", "gene_names_refseq": "MIOX", "protein_names_uniprotkb": "Inositol oxygenase; 1.13.99.1; Aldehyde reductase-like 6; MI oxygenase; Myo-inositol oxygenase", "protein_names_refseq": "MI oxygenase; aldehyde reductase-like 6; inositol oxygenase", "tax_id": 9823, "disease": "", "pathway": " (ssc:397189)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "11716759;20335317", "class_list": "", "function": "RSOR/MIOX modulates various downstream pathways affected by high-glucose ambience, and conceivably it plays a role in the pathobiology of tubulointerstitium in diabetic nephropathy., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008199 ferric iron binding;GO:0050113 inositol oxygenase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0016234 inclusion body", "go_biological_process": "GO:0003014 renal system process;GO:0019310 inositol catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q8WN98-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q8WNQ7-1", "uniprot_id": "GALNS_PIG", "mass": 57711.0, "length": 522, "protein_name": "N-acetylgalactosamine-6-sulfatase", "gene_name": "GALNS", "organism": "Pig", "refseq_name": "N-acetylgalactosamine-6-sulfatase precursor", "refseq_ac": "NP_999120", "gene_names_uniprotkb": "GALNS", "gene_names_refseq": "GALNS", "protein_names_uniprotkb": "N-acetylgalactosamine-6-sulfatase; 3.1.6.4; Chondroitinase; Chondroitinsulfatase; GalNAc6S sulfatase; Galactose-6-sulfate sulfatase; N-acetylgalactosamine-6-sulfate sulfatase", "protein_names_refseq": "N-acetylgalactosamine-6-sulfatase precursor; N-acetylgalactosamine-6-sulfatase; N-acetylgalactosamine-6-sulfate sulfatase; chondroitinase; chondroitinsulfatase; galNAc6S sulfatase; galactosamine (N-acetyl)-6-sulfate sulfatase (Morquio syndrome, mucopolysaccharidosis type IVA); galactose-6-sulfate sulfatase", "tax_id": 9823, "disease": "", "pathway": " (ssc:397000)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "12489154", "class_list": "", "function": "Lysosomal enzyme that hydrolyzes sulfate groups from glycosaminoglycans (GAGs), keratan sulfate (KS) and chondroitin-6-sulfate (C6S)., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0043890 N-acetylgalactosamine-6-sulfatase activity;GO:0046872 metal ion binding;GO:0004065 arylsulfatase activity", "go_cellular_component": "GO:0005764 lysosome", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q8WNQ7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q8WNW3-1", "uniprot_id": "PLAK_PIG", "mass": 81850.0, "length": 745, "protein_name": "Junction plakoglobin", "gene_name": "Jup", "organism": "Pig", "refseq_name": "junction plakoglobin", "refseq_ac": "NP_999488", "gene_names_uniprotkb": "Jup", "gene_names_refseq": "JUP", "protein_names_uniprotkb": "Junction plakoglobin", "protein_names_refseq": "junction plakoglobin; plakoglobin", "tax_id": 9823, "disease": "", "pathway": " (ssc:397592); (R-SSC-418990); (R-SSC-5218920); (R-SSC-6798695); (R-SSC-6805567); (R-SSC-6809371); (R-SSC-8980692); (R-SSC-9013026); (R-SSC-9013106); (R-SSC-9013148); (R-SSC-9013406); (R-SSC-9013407); (R-SSC-9762292); (R-SSC-9764561); (R-SSC-9766229); (R-SSC-9768727); (R-SSC-9958810); (R-SSC-9958825)", "pathway_count": 18, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Common junctional plaque protein. The membrane-associated plaques are architectural elements in an important strategic position to influence the arrangement and function of both the cytoskeleton and the cells within the tissue. The presence of plakoglobin in both the desmosomes and in the intermediate junctions suggests that it plays a central role in the structure and function of submembranous plaques. Acts as a substrate for VE-PTP and is required by it to stimulate VE-cadherin function in endothelial cells. Can replace beta-catenin in E-cadherin/catenin adhesion complexes which are proposed to couple cadherins to the actin cytoskeleton (By similarity). May promote axon outgrowth and motor fiber repair via DSP-mediated recruitment to outgrowth tips (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 5, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003713 transcription coactivator activity;GO:0045296 cadherin binding;GO:0019903 protein phosphatase binding;GO:0045294 alpha-catenin binding;GO:0016922 nuclear receptor binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005856 cytoskeleton;GO:0005912 adherens junction;GO:0030424 axon", "go_biological_process": "GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0098609 cell-cell adhesion;GO:0060070 canonical Wnt signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q8WNW3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q95242-1", "uniprot_id": "PECA1_PIG", "mass": 82379.0, "length": 740, "protein_name": "Platelet endothelial cell adhesion molecule", "gene_name": "PECAM1", "organism": "Pig", "refseq_name": "platelet endothelial cell adhesion molecule precursor", "refseq_ac": "NP_999072", "gene_names_uniprotkb": "PECAM1", "gene_names_refseq": "CD31; PECAM-1; PECAM1", "protein_names_uniprotkb": "Platelet endothelial cell adhesion molecule; PECAM-1", "protein_names_refseq": "platelet endothelial cell adhesion molecule precursor; platelet endothelial cell adhesion molecule; platelet/endothelial cell adhesion molecule (CD31 antigen); type I transmembrane endothelial adhesion molecule", "tax_id": 9823, "disease": "", "pathway": " (ssc:396941); (R-SSC-114608); (R-SSC-202733); (R-SSC-210990); (R-SSC-216083); (R-SSC-432142); (R-SSC-6798695)", "pathway_count": 7, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Cell adhesion molecule which is required for leukocyte transendothelial migration (TEM) under most inflammatory conditions. Tyr-692 plays a critical role in TEM and is required for efficient trafficking of PECAM1 to and from the lateral border recycling compartment (LBRC) and is also essential for the LBRC membrane to be targeted around migrating leukocytes. Trans-homophilic interaction may play a role in endothelial cell-cell adhesion via cell junctions. Heterophilic interaction with CD177 plays a role in transendothelial migration of neutrophils. Homophilic ligation of PECAM1 prevents macrophage-mediated phagocytosis of neighboring viable leukocytes by transmitting a detachment signal. Promotes macrophage-mediated phagocytosis of apoptotic leukocytes by tethering them to the phagocytic cells; PECAM1-mediated detachment signal appears to be disabled in apoptotic leukocytes. Modulates bradykinin receptor BDKRB2 activation. Regulates bradykinin- and hyperosmotic shock-induced ERK1/2 activation in endothelial cells. Induces susceptibility to atherosclerosis., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 11, "predicted_n_glycosites": 10, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 11, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004888 transmembrane signaling receptor activity", "go_cellular_component": "GO:0045121 membrane raft;GO:0009897 external side of plasma membrane;GO:0070161 anchoring junction", "go_biological_process": "GO:0006955 immune response;GO:0007155 cell adhesion;GO:0007166 cell surface receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q95242-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q95252-1", "uniprot_id": "ADRB3_PIG", "mass": 43611.0, "length": 407, "protein_name": "Beta-3 adrenergic receptor", "gene_name": "ADRB3", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "ADRB3; BAR3", "gene_names_refseq": "", "protein_names_uniprotkb": "Beta-3 adrenergic receptor; Beta-3 adrenoceptor; Beta-3 adrenoreceptor", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-390696)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "7592080", "class_list": "", "function": "G protein-coupled receptor for catecholamines that couples to both G(s) and G(i) proteins, leading to either activation or inhibition of adenylate cyclase and cAMP-dependent pathway, respectively. The rank order of potency for physiological agonists is norepinephrine > epinephrine (By similarity). Involved in the regulation of thermogenesis and lipolysis in brown and white adipose tissue, after coupling to G(s) proteins and stimulation of the cAMP-PKA axis (By similarity). Also activates lipolytic process by coupling to G(i) proteins and consequent initiation of the ERK1/2 MAP kinase cascade. Participates in relaxation of the blood vessels and the urinary bladder. Also mediates negative inotropic effects in cardiomyocytes through activation of an NO synthase pathway and subsequent increase in cGMP levels, possibly involving G(i/o) protein-mediated coupling (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "Q9MZ00", "ec_number_list": "", "go_molecular_function": "GO:0051379 epinephrine binding;GO:0004939 beta-adrenergic receptor activity;GO:0015052 beta3-adrenergic receptor activity;GO:0003925 G protein activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0043235 receptor complex", "go_biological_process": "GO:0007193 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway;GO:0043410 positive regulation of MAPK cascade;GO:0070374 positive regulation of ERK1 and ERK2 cascade;GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway;GO:0002025 norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q95252-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q95266-1", "uniprot_id": "KCC2D_PIG", "mass": 56389.0, "length": 499, "protein_name": "Calcium/calmodulin-dependent protein kinase type II subunit delta", "gene_name": "CAMK2D", "organism": "Pig", "refseq_name": "calcium/calmodulin-dependent protein kinase type II subunit delta", "refseq_ac": "NP_999546", "gene_names_uniprotkb": "CAMK2D", "gene_names_refseq": "CAMK2D", "protein_names_uniprotkb": "Calcium/calmodulin-dependent protein kinase type II subunit delta; 2.7.11.17; CaM kinase II subunit delta; CaMK-II subunit delta", "protein_names_refseq": "caM kinase II subunit delta; caMK-II subunit delta; calcium/calmodulin-dependent protein kinase (CaM kinase) II delta; calcium/calmodulin-dependent protein kinase II delta 2-subunit; calcium/calmodulin-dependent protein kinase type II subunit delta", "tax_id": 9823, "disease": "", "pathway": " (ssc:397674); (R-SSC-3371571); (R-SSC-399719); (R-SSC-438066); (R-SSC-5673001); (R-SSC-877300)", "pathway_count": 6, "publication_count": 1, "publication_id_list": "9083077", "class_list": "", "function": "Calcium/calmodulin-dependent protein kinase involved in the regulation of Ca(2+) homeostatis and excitation-contraction coupling (ECC) in heart by targeting ion channels, transporters and accessory proteins involved in Ca(2+) influx into the myocyte, Ca(2+) release from the sarcoplasmic reticulum (SR), SR Ca(2+) uptake and Na(+) and K(+) channel transport. Targets also transcription factors and signaling molecules to regulate heart function. In its activated form, is involved in the pathogenesis of dilated cardiomyopathy and heart failure. Contributes to cardiac decompensation and heart failure by regulating SR Ca(2+) release via direct phosphorylation of RYR2 Ca(2+) channel on 'Ser-2808'. In the nucleus, phosphorylates the MEF2 repressor HDAC4, promoting its nuclear export and binding to 14-3-3 protein, and expression of MEF2 and genes involved in the hypertrophic program. Is essential for left ventricular remodeling responses to myocardial infarction. In pathological myocardial remodeling acts downstream of the beta adrenergic receptor signaling cascade to regulate key proteins involved in ECC. Regulates Ca(2+) influx to myocytes by binding and phosphorylating the L-type Ca(2+) channel subunit beta-2 CACNB2. In addition to Ca(2+) channels, can target and regulate the cardiac sarcolemmal Na(+) channel Nav1.5/SCN5A and the K+ channel Kv4.3/KCND3, which contribute to arrhythmogenesis in heart failure. Phosphorylates phospholamban (PLN/PLB), an endogenous inhibitor of SERCA2A/ATP2A2, contributing to the enhancement of SR Ca(2+) uptake that may be important in frequency-dependent acceleration of relaxation (FDAR) and maintenance of contractile function during acidosis. May participate in the modulation of skeletal muscle function in response to exercise, by regulating SR Ca(2+) transport through phosphorylation of PLN/PLB and triadin, a ryanodine receptor-coupling factor. In response to interferon-gamma (IFN-gamma) stimulation, catalyzes phosphorylation of STAT1, stimulating the JAK-STAT signaling pathway (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 13, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005516 calmodulin binding;GO:0005524 ATP binding;GO:0004683 calcium/calmodulin-dependent protein kinase activity;GO:0106310 protein serine kinase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0014069 postsynaptic density;GO:0043005 neuron projection;GO:0042383 sarcolemma;GO:0033017 sarcoplasmic reticulum membrane", "go_biological_process": "GO:0060341 regulation of cellular localization;GO:0006468 protein phosphorylation;GO:1903076 regulation of protein localization to plasma membrane;GO:0048168 regulation of neuronal synaptic plasticity;GO:0010613 positive regulation of cardiac muscle hypertrophy", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q95266-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q95274-1", "uniprot_id": "TYB4_PIG", "mass": 5053.0, "length": 44, "protein_name": "Thymosin beta-4", "gene_name": "TMSB4", "organism": "Pig", "refseq_name": "thymosin beta-4", "refseq_ac": "NP_001135463", "gene_names_uniprotkb": "TMSB4", "gene_names_refseq": "TMSB4X; TMSB4", "protein_names_uniprotkb": "Thymosin beta-4; AcSDKP; N-acetyl-SDKP; Seraspenide; T beta-4", "protein_names_refseq": "t beta-4; thymosin beta-4", "tax_id": 9823, "disease": "", "pathway": " (ssc:733606); (R-SSC-114608)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "16971568", "class_list": "", "function": "Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization., [UniProtKB, UniProtKB]; Potent inhibitor of bone marrow derived stem cell differentiation (By similarity). Acts by inhibits the entry of hematopoietic pluripotent stem cells into the S-phase (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 4, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q2EN78", "ec_number_list": "", "go_molecular_function": "GO:0003785 actin monomer binding;GO:0140311 protein sequestering activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0005856 cytoskeleton", "go_biological_process": "GO:0007015 actin filament organization;GO:0030334 regulation of cell migration", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q95274-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q95ND5-1", "uniprot_id": "CASP3_PIG", "mass": 31379.0, "length": 277, "protein_name": "Caspase-3", "gene_name": "CASP3", "organism": "Pig", "refseq_name": "caspase-3", "refseq_ac": "NP_999296", "gene_names_uniprotkb": "CASP3", "gene_names_refseq": "CASP3", "protein_names_uniprotkb": "Caspase-3; 3.4.22.56; CASP-3", "protein_names_refseq": "CASP-3; caspase-3", "tax_id": 9823, "disease": "", "pathway": " (ssc:397244)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "11222676;11440638;15609044;17268855;17437340;19283610;21887717;26436384", "class_list": "", "function": "Both caspase-3-dependent and -independent pathways of programmed cell death increased upon Salmonella typhimurium infection., [RefSeq, PubMed]; Caspase-3 (CC3) was shown to be more abundant in early-cleaving and more developmentally competent embryos compared to late-cleaving and less developmentally competent embryos., [RefSeq, PubMed]; Clonidine administration prior to hypoxia prevents the hypoxia-induced increase in the activity of caspase-3 in the cerebral cortex., [RefSeq, PubMed]; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis, it proteolytically cleaves poly(ADP-ribose) polymerase PARP1 at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9 (CASP6, CASP7 and CASP9, respectively). Cleaves and inactivates interleukin-18 (IL18) (By similarity). Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity). Also involved in axon pruning during brain development (By similarity). Cleaves DSG2 in response to apoptosis resulting in a loss of full length DSG2 at desmosome cell junctions and subsequent loss of cell-cell adhesion (By similarity). Also cleaves JUP in response to apoptosis (By similarity). Cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes (By similarity). Cleaves and inhibits serine/threonine-protein kinase AKT1 in response to oxidative stress. Acts as an inhibitor of type I interferon production during virus-induced apoptosis by mediating cleavage of antiviral proteins CGAS, IRF3 and MAVS, thereby preventing cytokine overproduction. Also involved in pyroptosis by mediating cleavage and activation of gasdermin-E (GSDME) (By similarity). Cleaves XRCC4 and phospholipid scramblase proteins XKR4, XKR8 and XKR9, leading to promote phosphatidylserine exposure on apoptotic cell surface (By similarity). Cleaves BIRC6 following inhibition of BIRC6-caspase binding by DIABLO/SMAC (By similarity)., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]; Ischemic preconditioning exerts a powerful protective effect against hepatic ischemia-reperfusion injury in the early phase of reperfusion, which may be mediated by preservation of mitochondrial structure and inhibition of caspase-3 activity., [RefSeq, PubMed]; Suppressive effect of FSH and LH on p53 expression and caspase-3 activity with parallel increase in bcl-2 expression and increased P production was observed, [RefSeq, PubMed]; This study demonstrated that LAMPs from M. hyopneumoniae can induce apoptosis in St. Jude porcine lung epithelial cell line through the activation of caspase 3, caspase 8, cyt c, Bax, and p38 MAPK. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004175 endopeptidase activity;GO:0008047 enzyme activator activity;GO:0004197 cysteine-type endopeptidase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0031264 death-inducing signaling complex", "go_biological_process": "GO:0006508 proteolysis;GO:1902004 positive regulation of amyloid-beta formation;GO:0006915 apoptotic process;GO:0030216 keratinocyte differentiation;GO:0030218 erythrocyte differentiation", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q95ND5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q99028-1", "uniprot_id": "COMT_PIG", "mass": 20587.0, "length": 186, "protein_name": "Catechol O-methyltransferase", "gene_name": "COMT", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "COMT", "gene_names_refseq": "", "protein_names_uniprotkb": "Catechol O-methyltransferase; 2.1.1.6", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 2, "publication_id_list": "1847521;1932084", "class_list": "", "function": "Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. Also shortens the biological half-lives of certain neuroactive drugs, like L-DOPA, alpha-methyl DOPA and isoproterenol., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0000287 magnesium ion binding;GO:0016206 catechol O-methyltransferase activity", "go_cellular_component": "GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0016020 membrane;GO:0030424 axon;GO:0030425 dendrite", "go_biological_process": "GO:0006629 lipid metabolic process;GO:0032502 developmental process;GO:0042417 dopamine metabolic process;GO:0032259 methylation;GO:0042424 catecholamine catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q99028-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9BDJ5-1", "uniprot_id": "VNN1_PIG", "mass": 57156.0, "length": 513, "protein_name": "Pantetheinase", "gene_name": "VNN1", "organism": "Pig", "refseq_name": "pantetheinase precursor", "refseq_ac": "NP_999298", "gene_names_uniprotkb": "VNN1", "gene_names_refseq": "VNN1", "protein_names_uniprotkb": "Pantetheinase; 3.5.1.92; Pantetheine hydrolase; Vanin-1; Vascular non-inflammatory molecule 1", "protein_names_refseq": "pantetheinase precursor; pantetheinase; pantetheine hydrolase; vascular non-inflammatory molecule 1", "tax_id": 9823, "disease": "", "pathway": " (ssc:397246)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "10567687", "class_list": "", "function": "Amidohydrolase that hydrolyzes specifically one of the carboamide linkages in D-pantetheine thus recycling pantothenic acid (vitamin B5) and releasing cysteamine., [UniProtKB, PubMed]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0017159 pantetheine hydrolase activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0098552 side of membrane", "go_biological_process": "GO:0015939 pantothenate metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q9BDJ5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9BEC7-1", "uniprot_id": "NPL_PIG", "mass": 35062.0, "length": 319, "protein_name": "N-acetylneuraminate lyase", "gene_name": "NPL", "organism": "Pig", "refseq_name": "N-acetylneuraminate lyase", "refseq_ac": "NP_999236", "gene_names_uniprotkb": "NPL", "gene_names_refseq": "NPL", "protein_names_uniprotkb": "N-acetylneuraminate lyase; 4.1.3.3; N-acetylneuraminate pyruvate-lyase; N-acetylneuraminic acid aldolase; NALase; Sialate lyase; Sialate-pyruvate lyase; Sialic acid aldolase; Sialic acid lyase", "protein_names_refseq": "N-acetylneuraminate lyase; N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase); N-acetylneuraminic acid aldolase; NALase; acylneuraminate lyase; sialate lyase; sialate-pyruvate lyase; sialic acid aldolase; sialic acid lyase", "tax_id": 9823, "disease": "", "pathway": " (ssc:397141); (R-SSC-4085001)", "pathway_count": 2, "publication_count": 2, "publication_id_list": "10737328;11737202", "class_list": "", "function": "Catalyzes the cleavage of N-acetylneuraminic acid (sialic acid) to form pyruvate and N-acetylmannosamine via a Schiff base intermediate. It prevents sialic acids from being recycled and returning to the cell surface. Involved in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway., [UniProtKB, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008747 N-acetylneuraminate lyase activity", "go_cellular_component": "GO:0005737 cytoplasm", "go_biological_process": "GO:0005975 carbohydrate metabolic process;GO:0019262 N-acetylneuraminate catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q9BEC7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9GJR5-1", "uniprot_id": "HCST_PIG", "mass": 7930.0, "length": 79, "protein_name": "Hematopoietic cell signal transducer", "gene_name": "HCST", "organism": "Pig", "refseq_name": "hematopoietic cell signal transducer precursor", "refseq_ac": "NP_999307", "gene_names_uniprotkb": "HCST; DAP10", "gene_names_refseq": "DAP10; HCST", "protein_names_uniprotkb": "Hematopoietic cell signal transducer; DNAX-activation protein 10; Membrane protein DAP10", "protein_names_refseq": "DNAX-activation protein 10; hematopoietic cell signal transducer precursor; immunoreceptor DAP10; membrane protein DAP10", "tax_id": 9823, "disease": "", "pathway": " (ssc:397267); (R-SSC-198933)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "11398969", "class_list": "", "function": "Transmembrane adapter protein which associates with KLRK1 to form an activation receptor KLRK1-HCST in lymphoid and myeloid cells; this receptor plays a major role in triggering cytotoxicity against target cells expressing cell surface ligands such as MHC class I chain-related MICA and MICB, and UL16-binding proteins (ULBPs); these ligands are up-regulated by stress conditions and pathological state such as viral infection and tumor transformation. Functions as a docking site for PI3-kinase PIK3R1 and GRB2. Interaction of ULBPs with KLRK1-HCST triggers calcium mobilization and activation of the PIK3R1, MAP2K/ERK, and JAK2/STAT5 signaling pathways. Both PIK3R1 and GRB2 are required for full KLRK1-HCST-mediated activation and ultimate killing of target cells. In NK cells, KLRK1-HCST signaling directly induces cytotoxicity and enhances cytokine production initiated via DAP12/TYROBP-associated receptors. In T-cells, it provides primarily costimulation for TCR-induced signals. KLRK1-HCST receptor plays a role in immune surveillance against tumors and is required for cytolysis of tumors cells; indeed, melanoma cells that do not express KLRK1 ligands escape from immune surveillance mediated by NK cells (By similarity)., [UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005102 signaling receptor binding;GO:0043548 phosphatidylinositol 3-kinase binding", "go_cellular_component": "GO:0009986 cell surface;GO:0016020 membrane", "go_biological_process": "GO:0051897 positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction;GO:0050776 regulation of immune response", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q9GJR5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9GJX5-1", "uniprot_id": "CP4AL_PIG", "mass": 57216.0, "length": 504, "protein_name": "Taurochenodeoxycholic 6 alpha-hydroxylase", "gene_name": "CYP4A21", "organism": "Pig", "refseq_name": "taurochenodeoxycholic 6 alpha-hydroxylase", "refseq_ac": "NP_999590", "gene_names_uniprotkb": "CYP4A21", "gene_names_refseq": "CYP4A21", "protein_names_uniprotkb": "Taurochenodeoxycholic 6 alpha-hydroxylase; 1.14.14.57; CYPIVA21; Cytochrome P450 4A21", "protein_names_refseq": "CYPIVA21; cytochrome P450 4A21; cytochrome P450, family 4, subfamily A, polypeptide 21; taurochenodeoxycholic 6 alpha-hydroxylase; taurochenodeoxycholic acid 6 alpha-hydroxylase", "tax_id": 9823, "disease": "", "pathway": " (ssc:403327)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "11113117;14641109;3095476;7649186", "class_list": "", "function": "Catalyzes the 6 alpha hydroxylation oxidation of taurodeoxycholate to produce the pig specific bile acid taurohyocholic acid., [UniProtKB, PubMed, PubMed, PubMed]; Evolution of the CYP4A21 gene by gene duplication and gene conversion., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 1, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "Q70BW2;Q70BZ7", "ec_number_list": "", "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0033780 taurochenodeoxycholate 6alpha-hydroxylase activity", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006629 lipid metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q9GJX5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9GKE8-1", "uniprot_id": "CD47_PIG", "mass": 33253.0, "length": 303, "protein_name": "Leukocyte surface antigen CD47", "gene_name": "CD47", "organism": "Pig", "refseq_name": "leukocyte surface antigen CD47 precursor", "refseq_ac": "NP_999147", "gene_names_uniprotkb": "CD47", "gene_names_refseq": "CD47/IAP; CD47", "protein_names_uniprotkb": "Leukocyte surface antigen CD47; IAP; Integrin-associated protein", "protein_names_refseq": "IAP; integrin-associated protein; leukocyte surface antigen CD47 precursor; leukocyte surface antigen CD47", "tax_id": 9823, "disease": "", "pathway": " (ssc:397042); (R-SSC-202733); (R-SSC-216083); (R-SSC-391160); (R-SSC-6798695)", "pathway_count": 5, "publication_count": 3, "publication_id_list": "12153520;17360380;21203512", "class_list": "", "function": "Adhesive protein that mediates cell-to-cell interactions (PubMed:12153520). Acts as a receptor for thrombospondin THBS1 and as modulator of integrin signaling through the activation of heterotrimeric G proteins (PubMed:12153520). Involved in signal transduction, cardiovascular homeostasis, inflammation, apoptosis, angiogenesis, cellular self-renewal, and immunoregulation (By similarity). Plays a role in modulating pulmonary endothelin EDN1 signaling (By similarity). Modulates nitrous oxide (NO) signaling, in response to THBS1, hence playing a role as a pressor agent, supporting blood pressure (By similarity). Plays an important role in memory formation and synaptic plasticity in the hippocampus (By similarity). Receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation (By similarity). Positively modulates FAS-dependent apoptosis in T-cells, perhaps by enhancing FAS clustering (By similarity). Plays a role in suppressing angiogenesis and may be involved in metabolic dysregulation during normal aging (By similarity). In response to THBS1, negatively modulates wound healing. Inhibits stem cell self-renewal, in response to THBS1, probably by regulation of the stem cell transcription factors POU5F1/OCT4, SOX2, MYC/c-Myc and KLF4 (By similarity). May play a role in membrane transport and/or integrin dependent signal transduction (By similarity). May prevent premature elimination of red blood cells (By similarity)., [UniProtKB, UniProtKB, PubMed, UniProtKB, UniProtKB]; Amyloid-beta inhibits No-cGMP signaling in a CD36- and CD47-dependent manner Publication Status: Online-Only, [RefSeq, PubMed]; Genetic induction of human CD47 on porcine cells could provide inhibitory signaling to SIRPalpha on human macrophages, providing a novel approach to preventing macrophage-mediated xenograft rejection., [RefSeq, PubMed]", "predicted_glycosites": 4, "predicted_n_glycosites": 4, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0070053 thrombospondin receptor activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0070062 extracellular exosome", "go_biological_process": "GO:0022409 positive regulation of cell-cell adhesion;GO:0098609 cell-cell adhesion;GO:0050729 positive regulation of inflammatory response;GO:0050766 positive regulation of phagocytosis;GO:0002684 positive regulation of immune system process", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9GKE8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9GLF5-1", "uniprot_id": "NKG2D_PIG", "mass": 24773.0, "length": 214, "protein_name": "NKG2-D type II integral membrane protein", "gene_name": "KLRK1", "organism": "Pig", "refseq_name": "NKG2-D type II integral membrane protein", "refseq_ac": "NP_998978", "gene_names_uniprotkb": "KLRK1; NKG2D", "gene_names_refseq": "KLRK1; NKG2D", "protein_names_uniprotkb": "NKG2-D type II integral membrane protein; Killer cell lectin-like receptor subfamily K member 1; NK cell receptor D; NKG2-D-activating NK receptor", "protein_names_refseq": "NK cell receptor D; NKG2-D type II integral membrane protein; NKG2-D-activating NK receptor; killer cell lectin-like receptor subfamily K, member 1", "tax_id": 9823, "disease": "", "pathway": " (ssc:396737)", "pathway_count": 1, "publication_count": 3, "publication_id_list": "11398969;25063224;28494934", "class_list": "", "function": "Expression on intraepithelial lymphocytes and relation to adaptive intestinal immune system, [RefSeq, PubMed]; Functions as an activating and costimulatory receptor involved in immunosurveillance upon binding to various cellular stress-inducible ligands displayed at the surface of autologous tumor cells and virus-infected cells. Provides both stimulatory and costimulatory innate immune responses on activated killer (NK) cells, leading to cytotoxic activity. Acts as a costimulatory receptor for T-cell receptor (TCR) in CD8(+) T-cell-mediated adaptive immune responses by amplifying T-cell activation. Stimulates perforin-mediated elimination of ligand-expressing tumor cells. Signaling involves calcium influx, culminating in the expression of TNF. Participates in NK cell-mediated bone marrow graft rejection. May play a regulatory role in differentiation and survival of NK cells. Binds to ligands belonging to various subfamilies of MHC class I-related glycoproteins (By similarity)., [UniProtKB]; The effect of Bacillus cereus on the stress response of enterocytes, including the expression of NKG2D, is reported., [RefSeq, PubMed]", "predicted_glycosites": 4, "predicted_n_glycosites": 4, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "Q9GL58", "ec_number_list": "", "go_molecular_function": "GO:0030246 carbohydrate binding;GO:0038023 signaling receptor activity", "go_cellular_component": "GO:0009986 cell surface;GO:0009897 external side of plasma membrane", "go_biological_process": "GO:0007165 signal transduction;GO:0030154 cell differentiation;GO:0045087 innate immune response;GO:0002250 adaptive immune response;GO:0045954 positive regulation of natural killer cell mediated cytotoxicity", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9GLF5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9MYN5-1", "uniprot_id": "CDKN3_PIG", "mass": 23906.0, "length": 212, "protein_name": "Cyclin-dependent kinase inhibitor 3", "gene_name": "CDKN3", "organism": "Pig", "refseq_name": "cyclin-dependent kinase inhibitor 3", "refseq_ac": "NP_999485", "gene_names_uniprotkb": "CDKN3; KAP", "gene_names_refseq": "CDKN3; KAP", "protein_names_uniprotkb": "Cyclin-dependent kinase inhibitor 3; 3.1.3.16; 3.1.3.48; CDK2-associated dual-specificity phosphatase; Kinase-associated phosphatase", "protein_names_refseq": "CDK2-associated dual-specificity phosphatase; cyclin-dependent kinase inhibitor 3; kinase-associated phosphatase", "tax_id": 9823, "disease": "", "pathway": " (ssc:397589)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "12078753;12927088", "class_list": "", "function": "May play a role in cell cycle regulation. Dual specificity phosphatase active toward substrates containing either phosphotyrosine or phosphoserine residues. Dephosphorylates CDK2 at 'Thr-160' in a cyclin-dependent manner (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004722 protein serine/threonine phosphatase activity;GO:0004725 protein tyrosine phosphatase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0048471 perinuclear region of cytoplasm", "go_biological_process": "", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q9MYN5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9MYP4-1", "uniprot_id": "AAKG3_PIG", "mass": 56790.0, "length": 514, "protein_name": "5'-AMP-activated protein kinase subunit gamma-3", "gene_name": "PRKAG3", "organism": "Pig", "refseq_name": "5'-AMP-activated protein kinase subunit gamma-3", "refseq_ac": "NP_999242", "gene_names_uniprotkb": "PRKAG3", "gene_names_refseq": "PRKAG3", "protein_names_uniprotkb": "5'-AMP-activated protein kinase subunit gamma-3; AMPK gamma3; AMPK subunit gamma-3", "protein_names_refseq": "5'-AMP-activated protein kinase subunit gamma-3; AMP-activated protein kinase gamma subunit; AMPK gamma3; AMPK subunit gamma-3; protein kinase, AMP-activated, gamma 3 non-catalytic subunit", "tax_id": 9823, "disease": "", "pathway": " (ssc:397149)", "pathway_count": 1, "publication_count": 10, "publication_id_list": "10818001;14970697;15231235;15247217;15274139;22831392;24074175;26241465;27302990;31443641", "class_list": "", "function": "AMP/ATP-binding subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. AMPK also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. The AMPK gamma3 subunit is a non-catalytic subunit with a regulatory role in muscle energy metabolism. It mediates binding to AMP, ADP and ATP, leading to AMPK activation or inhibition: AMP-binding results in allosteric activation of alpha catalytic subunit (PRKAA1 or PRKAA2) both by inducing phosphorylation and preventing dephosphorylation of catalytic subunits. ADP also stimulates phosphorylation, without stimulating already phosphorylated catalytic subunit. ATP promotes dephosphorylation of catalytic subunit, rendering the AMPK enzyme inactive., [UniProtKB, UniProtKB]; Activity of glycogen synthase without the allosteric activator glucose 6-phosphate was decreased in gain of function AMPKgamma3(R200Q) relative to all other genotypes, [RefSeq, PubMed]; Allelic frequencies of PRKAG3 in several pig breeds, [RefSeq, PubMed]; Findings indicate that the genetic basis of muscle residual glycogen in swine can be mainly attributed to two major genes PRKAG3 and PHKG1 Publication Status: Online-Only, [RefSeq, PubMed]; Findings suggest that the R200Q mutation results in a constitutively active enzyme, leading to hyperaccumulation of glycogen due to the increased influx of glucose, [RefSeq, PubMed]; Genetic variation of PRKAG3 was studied in indigenous breeds of China., [RefSeq, PubMed]; Greater net lactate accumulation postmortem (i.e., glycolytic flux) coupled with a lower buffering capacity explains the lower ultimate pH of meat from AMPKgamma3(R200Q) mutant pigs., [RefSeq, PubMed]; The R225Q mutation of PRKAG3 is associated with higher basal AMPK activity and diminished AMP dependence, [RefSeq, PubMed]; The variation in the promoter region of the porcine PRKAG3 gene has associations with meat quality phenotypes, including traits which are influenced by glycolytic potential and muscle metabolism in a breed-dependent manner. Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q53ZT5;Q6WZ89", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0019901 protein kinase binding;GO:0016208 AMP binding;GO:0019887 protein kinase regulator activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0031588 nucleotide-activated protein kinase complex", "go_biological_process": "GO:0006110 regulation of glycolytic process;GO:0006633 fatty acid biosynthetic process;GO:0042149 cellular response to glucose starvation;GO:0045722 positive regulation of gluconeogenesis", "synthesized_glycan_count": 0, "hit_score": 1.1, "record_id": "Q9MYP4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9MYX7-1", "uniprot_id": "CTLA4_PIG", "mass": 24430.0, "length": 223, "protein_name": "Cytotoxic T-lymphocyte protein 4", "gene_name": "CTLA4", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "CTLA4", "gene_names_refseq": "", "protein_names_uniprotkb": "Cytotoxic T-lymphocyte protein 4; CTLA-4; Cytotoxic T-lymphocyte-associated antigen 4", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Inhibitory receptor acting as a major negative regulator of T-cell responses. Acts as a decoy receptor: the affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0140319 receptor decoy activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0009897 external side of plasma membrane", "go_biological_process": "GO:0050852 T cell receptor signaling pathway;GO:0002250 adaptive immune response;GO:0050853 B cell receptor signaling pathway;GO:0050868 negative regulation of T cell activation;GO:0045590 negative regulation of regulatory T cell differentiation", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q9MYX7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9MYY8-1", "uniprot_id": "TRXR1_PIG", "mass": 54904.0, "length": 499, "protein_name": "Thioredoxin reductase 1, cytoplasmic", "gene_name": "TXNRD1", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "TXNRD1", "gene_names_refseq": "", "protein_names_uniprotkb": "Thioredoxin reductase 1, cytoplasmic; 1.11.1.2; 1.8.1.9; Peroxidase TXNRD1; TR; Thioredoxin reductase TR1", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Reduces disulfide protein thioredoxin (Trx) to its dithiol-containing form. Homodimeric flavoprotein involved in the regulation of cellular redox reactions, growth and differentiation. A selenocysteine residue at the C-terminal active site is essential for catalysis. Also has reductase activity on hydrogen peroxide (H2O2)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004791 thioredoxin-disulfide reductase (NADPH) activity;GO:0042802 identical protein binding;GO:0071949 FAD binding;GO:0050137 NADPH peroxidase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005739 mitochondrion;GO:0005829 cytosol", "go_biological_process": "GO:0006979 response to oxidative stress;GO:0045454 cell redox homeostasis", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q9MYY8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9MZ15-1", "uniprot_id": "VDAC2_PIG", "mass": 31605.0, "length": 294, "protein_name": "Non-selective voltage-gated ion channel VDAC2", "gene_name": "VDAC2", "organism": "Pig", "refseq_name": "non-selective voltage-gated ion channel VDAC2", "refseq_ac": "NP_999534", "gene_names_uniprotkb": "VDAC2", "gene_names_refseq": "VDAC2", "protein_names_uniprotkb": "Non-selective voltage-gated ion channel VDAC2; VDAC-2", "protein_names_refseq": "VDAC-2; non-selective voltage-gated ion channel VDAC2; voltage-dependent anion-selective channel protein 2", "tax_id": 9823, "disease": "", "pathway": " (ssc:397659)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "19630752;26060891;30723633;37797697", "class_list": "", "function": "An important MYBL2-VDAC2-BECN1-BCL2L1 pathway linking autophagy suppression in the developing ovary, is reported., [RefSeq, PubMed]; Catalyzes the scrambling of phospholipids across the outer mitochondrial membrane; the mechanism is unrelated to channel activity and is capable of translocating both anionic and zwitterionic phospholipids., [UniProtKB, UniProtKB]; Data confirm the synthesis of VDAC1 and 2 subtypes in GV (germinal vesicle) and MII (meiosis II) stage porcine oocytes as well as their protein expression. Publication Status: Online-Only, [RefSeq, PubMed]; Deubiquitinase UCHL1 regulates estradiol synthesis by stabilizing voltage-dependent anion channel 2., [RefSeq, PubMed]; Non-selective voltage-gated ion channel that mediates the transport of anions and cations through the mitochondrion outer membrane and plasma membrane (By similarity). The channel adopts an open conformation at zero mV and a closed conformation at both positive and negative potentials (By similarity). There are two populations of channels; the main that functions in a lower open-state conductance with lower ion selectivity, that switch, in a voltage-dependent manner, from the open to a low-conducting 'closed' state and the other that has a normal ion selectivity in the typical high conductance, 'open' state (By similarity). Binds various lipids, including the sphingolipid ceramide, the phospholipid phosphatidylcholine, and the sterols cholesterol and oxysterol (By similarity). Binding of ceramide promotes the mitochondrial outer membrane permeabilization (MOMP) apoptotic pathway (By similarity). Associates with the translocase of the outer mitochondrial membrane (TOM) complex and PINK1 kinase at depolarized mitochondria, this interaction stabilizes PINK1 at the outer mitochondrial membrane and triggers downstream mitophagy by the recruitment of the E3 ubiquitin ligase PRKN (By similarity)., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 3, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A4X1SP14;F1S2F6", "ec_number_list": "", "go_molecular_function": "GO:0008142 oxysterol binding;GO:0005524 ATP binding;GO:0015485 cholesterol binding;GO:0031210 phosphatidylcholine binding;GO:0005244 voltage-gated monoatomic ion channel activity", "go_cellular_component": "GO:0005739 mitochondrion;GO:0005741 mitochondrial outer membrane;GO:0016020 membrane;GO:0046930 pore complex;GO:0097225 sperm midpiece", "go_biological_process": "GO:0006869 lipid transport;GO:0006820 monoatomic anion transport;GO:0097345 mitochondrial outer membrane permeabilization", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q9MZ15-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9MZS9-1", "uniprot_id": "KMO_PIG", "mass": 53998.0, "length": 471, "protein_name": "Kynurenine 3-monooxygenase", "gene_name": "KMO", "organism": "Pig", "refseq_name": "kynurenine 3-monooxygenase", "refseq_ac": "NP_999241", "gene_names_uniprotkb": "KMO", "gene_names_refseq": "KMO", "protein_names_uniprotkb": "Kynurenine 3-monooxygenase; 1.14.13.9; Fpk; Kynurenine 3-hydroxylase", "protein_names_refseq": "L-kynurenine 3-monooxygenase Fpk; fpk; kynurenine 3-monooxygenase", "tax_id": 9823, "disease": "", "pathway": " (ssc:397148); (R-SSC-71240)", "pathway_count": 2, "publication_count": 3, "publication_id_list": "10721109;20802227;32543654", "class_list": "", "function": "Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract., [UniProtKB, HAMAP, UniProtKB, UniProtKB, UniProtKB]; The carboxyl-terminal region of pig liver L-kynurenine 3-monooxygenase plays a dual role as a mitochondrial-targeting signal and an enzyme., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0071949 FAD binding;GO:0016174 NAD(P)H oxidase H2O2-forming activity;GO:0004502 kynurenine 3-monooxygenase activity", "go_cellular_component": "GO:0005741 mitochondrial outer membrane", "go_biological_process": "GO:0006569 L-tryptophan catabolic process;GO:0070189 kynurenine metabolic process;GO:0019674 NAD+ metabolic process;GO:0019805 quinolinate biosynthetic process;GO:0009651 response to salt stress", "synthesized_glycan_count": 0, "hit_score": 0.4, "record_id": "Q9MZS9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9N119-1", "uniprot_id": "3BHS_PIG", "mass": 41882.0, "length": 373, "protein_name": "3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase", "gene_name": "HSD3B", "organism": "Pig", "refseq_name": "3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase", "refseq_ac": "NP_001004049", "gene_names_uniprotkb": "HSD3B; 3b-HSD", "gene_names_refseq": "3B-HSD; HSD3B1; HSD3B", "protein_names_uniprotkb": "3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase; 3-beta-HSD; 3-beta-hydroxy-5-ene steroid dehydrogenase; Delta-5-3-ketosteroid isomerase; Progesterone reductase", "protein_names_refseq": "3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase; 3-beta-HSD; 3-beta-hydroxysteroid dehydrogenase/delta-5-delta-4 isomerase", "tax_id": 9823, "disease": "", "pathway": " (ssc:445539); (R-SSC-193048); (R-SSC-193993); (R-SSC-194002)", "pathway_count": 4, "publication_count": 8, "publication_id_list": "11683717;17060418;17647136;23581486;25130044;27512005;28877400;29576467", "class_list": "", "function": "3-beta-HSD is a bifunctional enzyme, that catalyzes the oxidative conversion of Delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids., [UniProtKB]; Glucocorticoid receptor binding to 3beta-HSD promoter is involved in the differential hepatic 3beta-HSD expression between boars and barrows., [RefSeq, PubMed]; It was concluded that the presence of apelin/APLNR in the CL of pigs and stimulatory effects of apelin on progesterone secretion and 3beta-HSD levels suggest potential auto/paracrine regulation by apelin in the luteal phase of the estrous cycle., [RefSeq, PubMed]; Significant sequence variations were found in the 5'flanking region of the 3beta-HSD gene, where differences in the number of TTAT repeats and 3 SNP were observed in the different breeds, [RefSeq, PubMed]; Study found that uncastrated Duroc pigs with the GG SNP5 genotype had significantly higher 3beta-HSD mRNA levels than did uncastrated Duroc pigs with other SNP5 genotypes., [RefSeq, PubMed]; The effects of androgen blockade on the expression of 3beta-hydroxysteroid dehydrogenase (3beta-HSD), CYP17, and 17beta-hydroxysteroid dehydrogenase type 1 (17beta-HSD1) in the porcine fetus are reported., [RefSeq, PubMed]; The expression of 3betaHSD mRNA was detected by the use of RT-PCR technique in all investigated samples isolated at different stages of pregnancy., [RefSeq, PubMed]; We found that adiponectin and insulin alone regulates the expression of StAR, CYP11A1 and HSD3B1 genes and secretion of P4 and A4 by the porcine endometrial and myometrial tissue explants during early pregnancy and the oestrous cycle., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003854 3-beta-hydroxy-Delta5-steroid dehydrogenase (NAD+) activity;GO:0004769 steroid Delta-isomerase activity;GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor", "go_cellular_component": "GO:0005737 cytoplasm;GO:0031966 mitochondrial membrane;GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0006694 steroid biosynthetic process;GO:0008207 C21-steroid hormone metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q9N119-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9N198-1", "uniprot_id": "FGF7_PIG", "mass": 22463.0, "length": 194, "protein_name": "Fibroblast growth factor 7", "gene_name": "FGF7", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "FGF7", "gene_names_refseq": "", "protein_names_uniprotkb": "Fibroblast growth factor 7; FGF-7; HBGF-7; Heparin-binding growth factor 7; KGF; Keratinocyte growth factor", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "10819782", "class_list": "", "function": "Plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation. Required for normal branching morphogenesis. Growth factor active on keratinocytes. Possible major paracrine effector of normal epithelial cell proliferation (By similarity)., [UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008201 heparin binding;GO:0008083 growth factor activity;GO:0005111 type 2 fibroblast growth factor receptor binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005737 cytoplasm", "go_biological_process": "GO:0043410 positive regulation of MAPK cascade;GO:0030324 lung development;GO:0051781 positive regulation of cell division;GO:0030334 regulation of cell migration;GO:0050679 positive regulation of epithelial cell proliferation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q9N198-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9N1X4-1", "uniprot_id": "SFTPD_PIG", "mass": 37986.0, "length": 378, "protein_name": "Pulmonary surfactant-associated protein D", "gene_name": "SFTPD", "organism": "Pig", "refseq_name": "pulmonary surfactant-associated protein D precursor", "refseq_ac": "NP_999275", "gene_names_uniprotkb": "SFTPD", "gene_names_refseq": "PSP-D; SFTPD; SP-D", "protein_names_uniprotkb": "Pulmonary surfactant-associated protein D; Lung surfactant protein D; PSP-D; SP-D", "protein_names_refseq": "lung surfactant protein D; pulmonary surfactant-associated protein D precursor; pulmonary surfactant-associated protein D; surfactant, pulmonary-associated protein D", "tax_id": 9823, "disease": "", "pathway": " (ssc:397198); (R-SSC-166016); (R-SSC-391160); (R-SSC-5683826); (R-SSC-5686938)", "pathway_count": 5, "publication_count": 6, "publication_id_list": "10640760;14672916;17420052;19010548;22921759;29769321", "class_list": "", "function": "Contributes to the lung's defense against inhaled microorganisms, organic antigens and toxins. Interacts with compounds such as bacterial lipopolysaccharides, oligosaccharides and fatty acids and modulates leukocyte action in immune response. May participate in the extracellular reorganization or turnover of pulmonary surfactant. Binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties (By similarity)., [UniProtKB]; Data show that interactions of surfactant protein D (pSP-D) with influenza A virus mediated by the N-linked carbohydrate moiety in pSP-D depend on the terminal sialic acids present on this moiety., [RefSeq, PubMed]; The authors demonstrated that the number and position of glycosylation sites determine viral susceptibility to the neutralizing activity of porcine SP-D., [RefSeq, PubMed]; The importance of SP-D in innate immunity is underlined by its expression at the potential ports of entry of pathogens: lung, tongue, intestinal tract, thymus, skin, gall bladder, lacrimal gland, esophagus, stomach, kidney, liver, prostate and spleen., [RefSeq, PubMed]; The presence of SP-D in endothelial cells which is NO-, PI(3)K/Akt- and Erk-dependent is demonstrated. It suggests a protective role of SP-D in these cells., [RefSeq, PubMed]", "predicted_glycosites": 2, "predicted_n_glycosites": 1, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 1, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 1, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 1, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 1, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 2, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 0, "biomarker_type": "", "glycan_count": 2, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0030246 carbohydrate binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0005771 multivesicular body", "go_biological_process": "GO:0043129 surfactant homeostasis;GO:0045087 innate immune response;GO:0048286 lung alveolus development;GO:0007585 respiratory gaseous exchange by respiratory system;GO:0050766 positive regulation of phagocytosis", "synthesized_glycan_count": 0, "hit_score": 1.0, "record_id": "Q9N1X4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9TTM9-1", "uniprot_id": "ADA1D_PIG", "mass": 60699.0, "length": 571, "protein_name": "Alpha-1D adrenergic receptor", "gene_name": "ADRA1D", "organism": "Pig", "refseq_name": "alpha-1D adrenergic receptor", "refseq_ac": "NP_001116545", "gene_names_uniprotkb": "ADRA1D", "gene_names_refseq": "ADRA1D", "protein_names_uniprotkb": "Alpha-1D adrenergic receptor; Alpha-1D adrenoceptor; Alpha-1D adrenoreceptor", "protein_names_refseq": "adrenergic, alpha-1D-, receptor; alpha-1D adrenergic receptor; alpha-1D adrenoceptor; alpha-1D adrenoreceptor", "tax_id": 9823, "disease": "", "pathway": " (ssc:552898); (R-SSC-390696); (R-SSC-416476); (R-SSC-416482)", "pathway_count": 4, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Alpha-1 adrenergic receptors are G protein-coupled receptors for catecholamines that signal through the G(q) family of G proteins, including G(q) and G(11). Upon activation, they stimulate the phosphatidylinositol-calcium second messenger pathway, leading to calcium release from intracellular stores and activation of protein kinase C (By similarity). ADRA1D binds the catecholamine ligands norepinephrine and epinephrine (By similarity)., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004937 alpha1-adrenergic receptor activity", "go_cellular_component": "GO:0005886 plasma membrane", "go_biological_process": "GO:0007204 positive regulation of cytosolic calcium ion concentration;GO:0007267 cell-cell signaling;GO:0043410 positive regulation of MAPK cascade;GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway;GO:0045907 positive regulation of vasoconstriction", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q9TTM9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9TU05-1", "uniprot_id": "MSHR_PIG", "mass": 34592.0, "length": 320, "protein_name": "Melanocyte-stimulating hormone receptor", "gene_name": "MC1R", "organism": "Pig", "refseq_name": "melanocyte-stimulating hormone receptor", "refseq_ac": "NP_001008690", "gene_names_uniprotkb": "MC1R", "gene_names_refseq": "MC1-R; MC1R; MSH-R", "protein_names_uniprotkb": "Melanocyte-stimulating hormone receptor; MC1-R; MSH-R; Melanocortin receptor 1", "protein_names_refseq": "MC1R melanocortin 1 receptor; melanocortin 1 receptor alpha melanocyte stimulating hormone receptor; melanocortin receptor 1; melanocyte-stimulating hormone receptor", "tax_id": 9823, "disease": "", "pathway": " (ssc:494018)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "15524286;16734703;16978185;25134014;28411032;30741434;38353621;9799269", "class_list": "", "function": "A 2-bp insertion (c.67_68insCC) in MC1R causes recessive white coat color in Bama miniature pigs, [RefSeq, PubMed]; Domestic and wild-type alleles at the MC1R and the NR6A1 genes were present in both domestic and wild populations. Findings of the distribution of MC1R alleles might be useful for tracing back the complex genetic history of autochthonous breeds., [RefSeq, PubMed]; G protein-coupled receptor that binds melanocyte-stimulating hormones (alpha, beta, and gamma-MSH) and adrenocorticotropic hormone/ACTH, which are peptide products of the POMC precursor protein. Upon activation, MC1R couples with the G(s) protein, stimulating adenylate cyclase and activating the cAMP-dependent signaling pathway (PubMed:9799269). This activation promotes melanogenesis, resulting in the production of eumelanin (black/brown) and pheomelanin (red/yellow) in melanocytes (PubMed:9799269). MC1R interacts with G protein-coupled receptor opsin 3/OPN3, which couples to G(i) proteins and inhibits the alpha-MSH-induced cAMP response, thereby reducing melanin synthesis (By similarity). Binding to Agouti/ASP precludes alpha-MSH-induced signaling, thereby downregulating melanogenesis (By similarity). Additionally, interaction with MGRN1 displaces the G(s) protein, further suppressing MC1R signaling (By similarity)., [UniProtKB, UniProtKB, PubMed, UniProtKB]; Melanocortin receptor 1 gene was not the principal factor affecting the coat color differences of Chinese native pig breeds, but could be used to trace the molecular evolution of pig breeds, [RefSeq, PubMed]; Mutational analysis of the MC1R loci in relation to coat color., [RefSeq, PubMed]; The MC1R gene, located on porcine chromosome 6, is responsible for the Extension coat color locus in Sus scrofa., [RefSeq, PubMed]; Variations in the MC1R gene are associated with coat color., [RefSeq, PubMed]; Whole-Genome Sequencing Reveals Rare Off-Target Mutations in MC1R-Edited Pigs Generated by Using CRISPR-Cas9 and Somatic Cell Nuclear Transfer., [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q2M499;Q2M4A0;Q2M4A3;Q6QZW6;Q9TV86;Q9TV87;Q9TV88;Q9XS81", "ec_number_list": "", "go_molecular_function": "GO:0046872 metal ion binding;GO:0004980 melanocyte-stimulating hormone receptor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane", "go_biological_process": "GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway;GO:0010468 regulation of gene expression;GO:0042438 melanin biosynthetic process;GO:0141163 positive regulation of cAMP/PKA signal transduction", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q9TU05-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9TUB5-1", "uniprot_id": "CLCA1_PIG", "mass": 100736.0, "length": 917, "protein_name": "Calcium-activated chloride channel regulator 1", "gene_name": "CLCA1", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "CLCA1; AECC", "gene_names_refseq": "", "protein_names_uniprotkb": "Calcium-activated chloride channel regulator 1; 3.4.-.-; Calcium-activated chloride channel family member 1; pCLCA1", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (ssc:397284)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "11015605;12107050;12408984;14988065", "class_list": "", "function": "May be involved in mediating calcium-activated chloride conductance. May play critical roles in goblet cell metaplasia, mucus hypersecretion, cystic fibrosis and AHR. May be involved in the regulation of mucus production and/or secretion by goblet cells. Involved in the regulation of tissue inflammation in the innate immune response. May play a role as a tumor suppressor. Induces MUC5AC. Induces a cAMP-dependent chloride conductance possibly through effects on CFTR in colon carcinoma cells., [UniProtKB, PubMed, PubMed, PubMed, PubMed]", "predicted_glycosites": 6, "predicted_n_glycosites": 6, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 6, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008237 metallopeptidase activity;GO:0046872 metal ion binding;GO:0005229 intracellularly calcium-gated chloride channel activity", "go_cellular_component": "GO:0005576 extracellular region;GO:0005886 plasma membrane", "go_biological_process": "GO:0006508 proteolysis;GO:0006816 calcium ion transport", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q9TUB5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9TUH9-1", "uniprot_id": "KCNE1_PIG", "mass": 14671.0, "length": 130, "protein_name": "Potassium voltage-gated channel subfamily E member 1", "gene_name": "KCNE1", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "KCNE1", "gene_names_refseq": "", "protein_names_uniprotkb": "Potassium voltage-gated channel subfamily E member 1; Delayed rectifier potassium channel subunit IsK; IKs producing slow voltage-gated potassium channel subunit beta Mink; Minimal potassium channel", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Ancillary protein that functions as a regulatory subunit of the voltage-gated potassium (Kv) channel complex composed of pore-forming and potassium-conducting alpha subunits and of regulatory beta subunits. KCNE1 beta subunit modulates the gating kinetics and enhances stability of the channel complex. Alters the gating of the delayed rectifier Kv channel containing KCNB1 alpha subunit. Associates with KCNQ1/KVLQT1 alpha subunit to form the slowly activating delayed rectifier cardiac potassium (IKs) channel responsible for ventricular muscle action potential repolarization. The outward current reaches its steady state only after 50 seconds. Assembly with KCNH2/HERG alpha subunit Kv channel may regulate the rapidly activating component of the delayed rectifying potassium current (IKr) in heart., [UniProtKB, UniProtKB]", "predicted_glycosites": 2, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005251 delayed rectifier potassium channel activity;GO:0015459 potassium channel regulator activity;GO:0044325 transmembrane transporter binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0045121 membrane raft;GO:0016324 apical plasma membrane;GO:0008076 voltage-gated potassium channel complex", "go_biological_process": "GO:0086011 membrane repolarization during action potential;GO:0086091 regulation of heart rate by cardiac conduction;GO:0060307 regulation of ventricular cardiac muscle cell membrane repolarization;GO:0086005 ventricular cardiac muscle cell action potential;GO:1902260 negative regulation of delayed rectifier potassium channel activity", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q9TUH9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9TUQ3-1", "uniprot_id": "CO7_PIG", "mass": 93062.0, "length": 843, "protein_name": "Complement component C7", "gene_name": "C7", "organism": "Pig", "refseq_name": "complement component C7 precursor", "refseq_ac": "NP_999447", "gene_names_uniprotkb": "C7", "gene_names_refseq": "C7", "protein_names_uniprotkb": "Complement component C7", "protein_names_refseq": "complement component C7 precursor; complement component C7", "tax_id": 9823, "disease": "", "pathway": " (ssc:397526)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "10878384", "class_list": "", "function": "Component of the membrane attack complex (MAC), a multiprotein complex activated by the complement cascade, which inserts into a target cell membrane and forms a pore, leading to target cell membrane rupture and cell lysis (PubMed:10878384). The MAC is initiated by proteolytic cleavage of C5 into complement C5b in response to the classical, alternative, lectin and GZMK complement pathways. The complement pathways consist in a cascade of proteins that leads to phagocytosis and breakdown of pathogens and signaling that strengthens the adaptive immune system. C7 serves as a membrane anchor. During MAC assembly, associates with C5b and C6 to form the C5b-7 complex, a key lipophilic precursor of the MAC complex, which associates with the outer leaflet and reduces the energy for membrane bending (By similarity)., [UniProtKB, UniProtKB, PubMed]", "predicted_glycosites": 6, "predicted_n_glycosites": 2, "predicted_o_glycosites": 0, "predicted_c_glycosites": 4, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 6, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "", "go_cellular_component": "GO:0005615 extracellular space;GO:0005579 membrane attack complex;GO:0044218 other organism cell membrane", "go_biological_process": "GO:0031640 killing of cells of another organism;GO:0006958 complement activation, classical pathway;GO:0006956 complement activation;GO:0006957 complement activation, alternative pathway;GO:0160257 complement activation, GZMK pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q9TUQ3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9TV36-1", "uniprot_id": "FBN1_PIG", "mass": 312699.0, "length": 2871, "protein_name": "Fibrillin-1", "gene_name": "FBN1", "organism": "Pig", "refseq_name": "fibrillin-1 precursor", "refseq_ac": "NP_001001771", "gene_names_uniprotkb": "FBN1", "gene_names_refseq": "FBN1", "protein_names_uniprotkb": "Fibrillin-1", "protein_names_refseq": "fibrillin-1 precursor", "tax_id": 9823, "disease": "", "pathway": " (ssc:414836)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "10036187;28111381", "class_list": "", "function": "Hormone that targets the liver to increase plasma glucose levels. Secreted by white adipose tissue and circulates in the plasma. Acts in response to fasting and promotes blood glucose elevation by binding to the surface of hepatocytes. Promotes hepatocyte glucose release by activating the protein kinase A activity in the liver, resulting in rapid glucose release into the circulation., [UniProtKB, UniProtKB]; Structural component of the 10-12 nm diameter microfibrils of the extracellular matrix, which conveys both structural and regulatory properties to load-bearing connective tissues. Fibrillin-1-containing microfibrils provide long-term force bearing structural support. In tissues such as the lung, blood vessels and skin, microfibrils form the periphery of the elastic fiber, acting as a scaffold for the deposition of elastin. In addition, microfibrils can occur as elastin-independent networks in tissues such as the ciliary zonule, tendon, cornea and glomerulus where they provide tensile strength and have anchoring roles. Fibrillin-1 also plays a key role in tissue homeostasis through specific interactions with growth factors, such as the bone morphogenetic proteins (BMPs), growth and differentiation factors (GDFs) and latent transforming growth factor-beta-binding proteins (LTBPs), cell-surface integrins and other extracellular matrix protein and proteoglycan components. Regulates osteoblast maturation by controlling TGF-beta bioavailability and calibrating TGF-beta and BMP levels, respectively. Negatively regulates osteoclastogenesis by binding and sequestering an osteoclast differentiation and activation factor TNFSF11. This leads to disruption of TNFSF11-induced Ca(2+) signaling and impairment of TNFSF11-mediated nuclear translocation and activation of transcription factor NFATC1 which regulates genes important for osteoclast differentiation and function. Mediates cell adhesion via its binding to cell surface receptors integrins ITGAV:ITGB3 and ITGA5:ITGB1. Binds heparin and this interaction plays an important role in the assembly of microfibrils., [UniProtKB, UniProtKB, UniProtKB]; These results suggest that the establishment of the DNA methylation pattern within the FBN1 CpG island shore occurs after the blastocyst stage, likely during organogenesis. In conclusion, Hypo-allele ratios of the FBN1 CpG island shore correlated with FBN1 expression levels in porcine tissues., [RefSeq, PubMed]", "predicted_glycosites": 36, "predicted_n_glycosites": 15, "predicted_o_glycosites": 21, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 36, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008201 heparin binding;GO:0005509 calcium ion binding;GO:0005179 hormone activity;GO:0005201 extracellular matrix structural constituent", "go_cellular_component": "GO:0005576 extracellular region;GO:0031012 extracellular matrix;GO:0001527 microfibril", "go_biological_process": "GO:0042593 glucose homeostasis;GO:0006006 glucose metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q9TV36-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9TV61-1", "uniprot_id": "MYH1_PIG", "mass": 223173.0, "length": 1939, "protein_name": "Myosin-1", "gene_name": "MYH1", "organism": "Pig", "refseq_name": "myosin-1", "refseq_ac": "NP_001098421", "gene_names_uniprotkb": "MYH1", "gene_names_refseq": "MYH1", "protein_names_uniprotkb": "Myosin-1; MyHC-2x; Myosin heavy chain 1; Myosin heavy chain 2x; Myosin heavy chain, skeletal muscle, adult 1", "protein_names_refseq": "myHC-2x; myosin heavy chain 1; myosin heavy chain 2x; myosin heavy chain, skeletal muscle, adult 1; myosin-1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100125538)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "26847462", "class_list": "", "function": "Required for normal hearing. It plays a role in cochlear amplification of auditory stimuli, likely through the positive regulation of prestin (SLC26A5) activity and outer hair cell (OHC) electromotility., [UniProtKB, UniProtKB]; The variants at L884T, K972C, N981G, and Q1285C in MYH1 in Jeju Native Pig might represent a cause for the poor growth performance for this breed Publication Status: Online-Only, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 37, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005516 calmodulin binding;GO:0005524 ATP binding;GO:0051015 actin filament binding;GO:0000146 microfilament motor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0032982 myosin filament;GO:0030016 myofibril;GO:0016460 myosin II complex", "go_biological_process": "GO:0006936 muscle contraction;GO:0007605 sensory perception of sound", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q9TV61-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9TV62-1", "uniprot_id": "MYH4_PIG", "mass": 223236.0, "length": 1937, "protein_name": "Myosin-4", "gene_name": "MYH4", "organism": "Pig", "refseq_name": "myosin-4", "refseq_ac": "NP_001116613", "gene_names_uniprotkb": "MYH4", "gene_names_refseq": "MYH4", "protein_names_uniprotkb": "Myosin-4; MyHC-2b; Myosin heavy chain 2b; Myosin heavy chain 4; Myosin heavy chain, skeletal muscle, fetal", "protein_names_refseq": "myHC-2b; myosin heavy chain 2b; myosin heavy chain 4; myosin heavy chain, skeletal muscle, fetal; myosin-4", "tax_id": 9823, "disease": "", "pathway": " (ssc:100144306)", "pathway_count": 1, "publication_count": 2, "publication_id_list": "25469802;26271027", "class_list": "", "function": "MYH4 is differentially expressed during myogenesis and is likely regulated by the CArG-Box promoter response element in domestic pigs. Publication Status: Online-Only, [RefSeq, PubMed]; Muscle contraction., [UniProtKB]; T allele may enhance expression level of MYH4 gene and then the portion of IIb type fiber in the muscle be increased by the T allelle, [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 39, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005516 calmodulin binding;GO:0005524 ATP binding;GO:0051015 actin filament binding;GO:0003725 double-stranded RNA binding;GO:0000146 microfilament motor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0032982 myosin filament;GO:0030016 myofibril;GO:0016460 myosin II complex", "go_biological_process": "GO:0006936 muscle contraction", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "Q9TV62-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9TV63-1", "uniprot_id": "MYH2_PIG", "mass": 223150.0, "length": 1939, "protein_name": "Myosin-2", "gene_name": "MYH2", "organism": "Pig", "refseq_name": "myosin-2", "refseq_ac": "NP_999301", "gene_names_uniprotkb": "MYH2", "gene_names_refseq": "MYH2", "protein_names_uniprotkb": "Myosin-2; MyHC-2a; Myosin heavy chain 2a; Myosin heavy chain 2; Myosin heavy chain, skeletal muscle, adult 2", "protein_names_refseq": "fast myosin heavy chain; myHC-2a; myosin heavy chain 2a; myosin heavy chain, skeletal muscle, adult 2; myosin-2", "tax_id": 9823, "disease": "", "pathway": " (ssc:397256)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Myosins are actin-based motor molecules with ATPase activity essential for muscle contraction., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 37, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005516 calmodulin binding;GO:0005524 ATP binding;GO:0051015 actin filament binding;GO:0000146 microfilament motor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0032982 myosin filament;GO:0030016 myofibril;GO:0016460 myosin II complex", "go_biological_process": "GO:0006936 muscle contraction", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q9TV63-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9XS72-1", "uniprot_id": "CD1A_PIG", "mass": 38631.0, "length": 339, "protein_name": "T-cell surface glycoprotein CD1a", "gene_name": "CD1A", "organism": "Pig", "refseq_name": "T-cell surface glycoprotein CD1a precursor", "refseq_ac": "NP_998996", "gene_names_uniprotkb": "CD1A; CD1.1", "gene_names_refseq": "CD1.1; CD1A; cd1a1", "protein_names_uniprotkb": "T-cell surface glycoprotein CD1a", "protein_names_refseq": "CD1A1 antigen; T-cell surface glycoprotein CD1a precursor; T-cell surface glycoprotein CD1a", "tax_id": 9823, "disease": "", "pathway": " (ssc:396785)", "pathway_count": 1, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells., [UniProtKB]", "predicted_glycosites": 3, "predicted_n_glycosites": 3, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 3, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0030883 endogenous lipid antigen binding;GO:0030884 exogenous lipid antigen binding;GO:0071723 lipopeptide binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0045121 membrane raft;GO:0009897 external side of plasma membrane;GO:0010008 endosome membrane", "go_biological_process": "GO:0006955 immune response;GO:0002250 adaptive immune response;GO:0001916 positive regulation of T cell mediated cytotoxicity;GO:0048007 antigen processing and presentation, exogenous lipid antigen via MHC class Ib;GO:0048006 antigen processing and presentation, endogenous lipid antigen via MHC class Ib", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q9XS72-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9XSJ9-1", "uniprot_id": "CD3Z_PIG", "mass": 18568.0, "length": 163, "protein_name": "T-cell surface glycoprotein CD3 zeta chain", "gene_name": "CD247", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "CD247; CD3Z", "gene_names_refseq": "", "protein_names_uniprotkb": "T-cell surface glycoprotein CD3 zeta chain; T-cell receptor T3 zeta chain", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 0, "publication_id_list": "", "class_list": "", "function": "Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD247/CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of downstream signaling pathways. CD247/CD3Z ITAMs phosphorylation creates multiple docking sites for the protein kinase ZAP70 leading to ZAP70 phosphorylation and its conversion into a catalytically active enzyme. Plays an important role in intrathymic T-cell differentiation. Additionally, participates in the activity-dependent synapse formation of retinal ganglion cells (RGCs) in both the retina and dorsal lateral geniculate nucleus (dLGN)., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 8, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004888 transmembrane signaling receptor activity;GO:0030674 protein-macromolecule adaptor activity;GO:0042803 protein homodimerization activity", "go_cellular_component": "GO:0042105 alpha-beta T cell receptor complex;GO:0033001 Fc-gamma receptor III complex", "go_biological_process": "GO:0050852 T cell receptor signaling pathway;GO:0002250 adaptive immune response", "synthesized_glycan_count": 0, "hit_score": 0.1, "record_id": "Q9XSJ9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9XSW2-1", "uniprot_id": "ESR2_PIG", "mass": 58850.0, "length": 526, "protein_name": "Estrogen receptor beta", "gene_name": "ESR2", "organism": "Pig", "refseq_name": "estrogen receptor beta", "refseq_ac": "NP_001001533", "gene_names_uniprotkb": "ESR2; NR3A2", "gene_names_refseq": "ER-beta; ER2; ESR2", "protein_names_uniprotkb": "Estrogen receptor beta; ER-beta; Nuclear receptor subfamily 3 group A member 2", "protein_names_refseq": "estrogen receptor 2 (ER beta); estrogen receptor beta; nuclear receptor subfamily 3 group A member 2", "tax_id": 9823, "disease": "", "pathway": " (ssc:396697)", "pathway_count": 1, "publication_count": 8, "publication_id_list": "14522825;15046395;15943697;19645857;22212297;26244666;26568065;27824510", "class_list": "", "function": "Downregulation of the ERs, particularly ERalpha in the myometrium and endometrial stroma, might be a relevant mechanism in the antagonism of estrogenic effects by dihydrotestosterone in the pig uterus., [RefSeq, PubMed]; Findings suggest that testicular oestrogen receptors alpha and beta may be important factors contributing to onset and maintenance of spermatogenesis in the boar, [RefSeq, PubMed]; Nuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1/ER-alpha, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner., [UniProtKB, UniProtKB]; Results might shed new light on the roles of estrogen receptor 2(ESR2) in spermatogenesis as candidate for boar fertility, [RefSeq, PubMed]; Results suggest that expression levels of protease activated receptors 1 and 2 (PAR-1 and PAR-2) associate with breast cancer outcome in an estrogen receptor (ER)-dependent manner. Publication Status: Online-Only, [RefSeq, PubMed]; Steroid hormones, AhR and estrogen receptor beta are affected by TCDD and genistein in granulosa cells of medium porcine follicles, [RefSeq, PubMed]; Study is the first one to demonstrate the presence of estrogen receptors alpha and beta in the porcine uterus not only at the beginning but also at mid- and late pregnancy, [RefSeq, PubMed]; The results of the present study suggest the involvement of estrogen receptor beta in estrogen modulation of pig epididymal function, [RefSeq, PubMed]; There were no statistical differences between the BB genotype and the AB genotype of ESR2 locus in regard to the examined traits. However, a noticeable superiority (P < 0.01) of the BB genotype compared to the homozygous AA genotype, adding almost 2 piglets/litter in TNB and NBA trait, was found., [RefSeq, PubMed]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 2, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "Q9BDW5", "ec_number_list": "", "go_molecular_function": "GO:0034056 estrogen response element binding;GO:0008270 zinc ion binding;GO:0005496 steroid binding;GO:0004879 nuclear receptor activity;GO:0030284 nuclear estrogen receptor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0000785 chromatin", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006357 regulation of transcription by RNA polymerase II;GO:0045893 positive regulation of DNA-templated transcription;GO:0071392 cellular response to estradiol stimulus;GO:0030520 estrogen receptor signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.9, "record_id": "Q9XSW2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9XSW3-1", "uniprot_id": "MBL2_PIG", "mass": 25523.0, "length": 240, "protein_name": "Mannose-binding protein C", "gene_name": "MBL2", "organism": "Pig", "refseq_name": "mannose-binding protein C precursor", "refseq_ac": "NP_999290", "gene_names_uniprotkb": "MBL2", "gene_names_refseq": "MBL2; MBL; MBP-C; pMBP-27", "protein_names_uniprotkb": "Mannose-binding protein C; 27 kDa mannan-binding protein monomeric subunit; MBL; MBP-C; Mannose-binding lectin; pMBP-27", "protein_names_refseq": "27 kDa mannan-binding protein monomeric subunit; mannan-binding lectin C; mannose-binding lectin (protein C) 2, soluble (opsonic defect); mannose-binding lectin C; mannose-binding protein C precursor; mannose-binding protein C", "tax_id": 9823, "disease": "", "pathway": " (ssc:397230)", "pathway_count": 1, "publication_count": 4, "publication_id_list": "11298833;17194476;17284229;8602463", "class_list": "", "function": "Calcium-dependent lectin, which acts as a pattern recognition receptor that initiates the lectin pathway of the complement system, a cascade of proteins that leads to phagocytosis and breakdown of pathogens and signaling that strengthens the adaptive immune system (PubMed:11298833, PubMed:17284229, PubMed:8602463). Specifically recognizes and binds the mannose moiety of carbohydrates on the pathogen surface, activating the MASP1 serine protease and initiating the proteolytic cascade of the lectin complement pathway (PubMed:11298833, PubMed:17284229, PubMed:8602463)., [UniProtKB, PubMed, PubMed, PubMed]; MBL1 was also found to be expressed in the lung, testis and brain, whereas low expression of MBL2 was detected in the testis and kidney., [RefSeq, PubMed]; MBL2 polymorphisms were associated with some disease groups and with the presence of some etiologic agents, [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0SVI8;Q9TR20", "ec_number_list": "", "go_molecular_function": "GO:0046872 metal ion binding;GO:0005537 D-mannose binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0009986 cell surface;GO:0005771 multivesicular body;GO:0106139 symbiont cell surface", "go_biological_process": "GO:0043129 surfactant homeostasis;GO:0050766 positive regulation of phagocytosis;GO:0001867 complement activation, lectin pathway;GO:0006958 complement activation, classical pathway", "synthesized_glycan_count": 0, "hit_score": 0.5, "record_id": "Q9XSW3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "Q9XT10-1", "uniprot_id": "GLUT4_PIG", "mass": 18208.0, "length": 174, "protein_name": "Solute carrier family 2, facilitated glucose transporter member 4", "gene_name": "SLC2A4", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "SLC2A4; GLUT4", "gene_names_refseq": "", "protein_names_uniprotkb": "Solute carrier family 2, facilitated glucose transporter member 4; GLUT-4; Glucose transporter type 4, insulin-responsive", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "10784183", "class_list": "", "function": "Insulin-regulated facilitative glucose transporter, which plays a key role in removal of glucose from circulation. Response to insulin is regulated by its intracellular localization: in the absence of insulin, it is efficiently retained intracellularly within storage compartments in muscle and fat cells. Upon insulin stimulation, translocates from these compartments to the cell surface where it transports glucose from the extracellular milieu into the cell., [UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 1, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 1, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0055056 D-glucose transmembrane transporter activity;GO:0015304 D-glucose uniporter activity", "go_cellular_component": "GO:0005886 plasma membrane;GO:0048471 perinuclear region of cytoplasm;GO:0012505 endomembrane system;GO:0030659 cytoplasmic vesicle membrane;GO:0032593 insulin-responsive compartment", "go_biological_process": "GO:1904659 D-glucose transmembrane transport;GO:0044381 glucose import in response to insulin stimulus", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "Q9XT10-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SI77-1", "uniprot_id": "F1SI77_PIG", "mass": 46935.0, "length": 416, "protein_name": "Creatine kinase U-type, mitochondrial", "gene_name": "CKMT1A", "organism": "Pig", "refseq_name": "creatine kinase U-type, mitochondrial isoform X1", "refseq_ac": "XP_003121596", "gene_names_uniprotkb": "CKMT1A", "gene_names_refseq": "CKMT1A; CKMT1B; CKMT1; Mia-CK; U-MtCK", "protein_names_uniprotkb": "Creatine kinase U-type, mitochondrial; 2.7.3.2; Acidic-type mitochondrial creatine kinase; Ubiquitous mitochondrial creatine kinase", "protein_names_refseq": "creatine kinase U-type, mitochondrial isoform X1", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-71288)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004111 creatine kinase activity;GO:0005524 ATP binding", "go_cellular_component": "GO:0005743 mitochondrial inner membrane;GO:0005739 mitochondrion", "go_biological_process": "GO:0046314 phosphocreatine biosynthetic process;GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SI77-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1S414-1", "uniprot_id": "F1S414_PIG", "mass": 128602.0, "length": 1133, "protein_name": "Inositol polyphosphate-5-phosphatase F", "gene_name": "INPP5F", "organism": "Pig", "refseq_name": "phosphatidylinositide phosphatase SAC2 isoform X1", "refseq_ac": "XP_005671564", "gene_names_uniprotkb": "INPP5F", "gene_names_refseq": "INPP5F", "protein_names_uniprotkb": "Inositol polyphosphate-5-phosphatase F", "protein_names_refseq": "phosphatidylinositide phosphatase SAC2 isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100144587); (R-SSC-1660516)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0016791 phosphatase activity;GO:0042803 protein homodimerization activity;GO:0034595 phosphatidylinositol phosphate 5-phosphatase activity;GO:0052833 inositol monophosphate 4-phosphatase activity;GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity", "go_cellular_component": "GO:0005769 early endosome;GO:0005905 clathrin-coated pit;GO:0030424 axon;GO:0030425 dendrite;GO:0043025 neuronal cell body", "go_biological_process": "GO:0008344 adult locomotory behavior;GO:2000145 regulation of cell motility;GO:0001921 positive regulation of receptor recycling;GO:0072583 clathrin-dependent endocytosis;GO:0046856 phosphatidylinositol dephosphorylation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1S414-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1S3U0-1", "uniprot_id": "F1S3U0_PIG", "mass": 37782.0, "length": 331, "protein_name": "Galactose-1-phosphate uridylyltransferase", "gene_name": "GALT", "organism": "Pig", "refseq_name": "galactose-1-phosphate uridylyltransferase isoform X2", "refseq_ac": "XP_005668100", "gene_names_uniprotkb": "GALT", "gene_names_refseq": "GALT", "protein_names_uniprotkb": "Galactose-1-phosphate uridylyltransferase; 2.7.7.12", "protein_names_refseq": "galactose-1-phosphate uridylyltransferase isoform X2", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-70370)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Plays an important role in galactose metabolism., [UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0008108 UDP-glucose:hexose-1-phosphate uridylyltransferase activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005794 Golgi apparatus", "go_biological_process": "GO:0006012 galactose metabolic process;GO:0033499 galactose catabolic process via UDP-galactose, Leloir pathway;GO:0006011 UDP-alpha-D-glucose metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1S3U0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1RSI6-1", "uniprot_id": "F1RSI6_PIG", "mass": 48241.0, "length": 431, "protein_name": "STE20-related kinase adapter protein alpha", "gene_name": "STRADA", "organism": "Pig", "refseq_name": "STE20-related kinase adapter protein alpha isoform X1", "refseq_ac": "XP_020922432", "gene_names_uniprotkb": "STRADA", "gene_names_refseq": "STRADA", "protein_names_uniprotkb": "STE20-related kinase adapter protein alpha; STE20-related adapter protein", "protein_names_refseq": "STE20-related kinase adapter protein alpha isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100513305); (R-SSC-380972)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A4X1T392", "ec_number_list": "", "go_molecular_function": "GO:0004672 protein kinase activity;GO:0005524 ATP binding;GO:0043539 protein serine/threonine kinase activator activity;GO:0019900 kinase binding", "go_cellular_component": "GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0032991 protein-containing complex;GO:1902554 serine/threonine protein kinase complex;GO:0005654 nucleoplasm", "go_biological_process": "GO:0006611 protein export from nucleus", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1RSI6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1RS44-1", "uniprot_id": "F1RS44_PIG", "mass": 78204.0, "length": 688, "protein_name": "Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase", "gene_name": "NGLY1", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "NGLY1", "gene_names_refseq": "", "protein_names_uniprotkb": "Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase; 3.5.1.52; N-glycanase 1; Peptide:N-glycanase", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-532668)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Specifically deglycosylates the denatured form of N-linked glycoproteins in the cytoplasm and assists their proteasome-mediated degradation. Cleaves the beta-aspartyl-glucosamine (GlcNAc) of the glycan and the amide side chain of Asn, converting Asn to Asp. Prefers proteins containing high-mannose over those bearing complex type oligosaccharides. Can recognize misfolded proteins in the endoplasmic reticulum that are exported to the cytosol to be destroyed and deglycosylate them, while it has no activity toward native proteins. Deglycosylation is a prerequisite for subsequent proteasome-mediated degradation of some, but not all, misfolded glycoproteins., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0000224 peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity;GO:0046872 metal ion binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005634 nucleus;GO:0005829 cytosol", "go_biological_process": "GO:0006516 glycoprotein catabolic process;GO:0030513 positive regulation of BMP signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1RS44-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1S9W8-1", "uniprot_id": "F1S9W8_PIG", "mass": 76164.0, "length": 677, "protein_name": "Kinesin light chain", "gene_name": "KLC1", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "KLC1", "gene_names_refseq": "", "protein_names_uniprotkb": "Kinesin light chain", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-2132295); (R-SSC-5625970); (R-SSC-6811434); (R-SSC-983189)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Kinesin is a microtubule-associated force-producing protein that play a role in organelle transport., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0019894 kinesin binding", "go_cellular_component": "GO:0005874 microtubule;GO:0005871 kinesin complex;GO:0005737 cytoplasm", "go_biological_process": "GO:0007018 microtubule-based movement", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1S9W8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1RSH5-1", "uniprot_id": "F1RSH5_PIG", "mass": 70591.0, "length": 629, "protein_name": "Mbt domain containing 1", "gene_name": "MBTD1", "organism": "Pig", "refseq_name": "MBT domain-containing protein 1 isoform X7", "refseq_ac": "XP_020922885", "gene_names_uniprotkb": "MBTD1", "gene_names_refseq": "MBTD1", "protein_names_uniprotkb": "Mbt domain containing 1", "protein_names_refseq": "MBT domain-containing protein 1 isoform X7", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008270 zinc ion binding;GO:0003682 chromatin binding;GO:0042393 histone binding;GO:0062060 NuA4 histone acetyltransferase complex binding;GO:0140005 histone H4K20me2 reader activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0035267 NuA4 histone acetyltransferase complex;GO:0035861 site of double-strand break", "go_biological_process": "GO:0006351 DNA-templated transcription;GO:0006355 regulation of DNA-templated transcription;GO:0006325 chromatin organization;GO:0045892 negative regulation of DNA-templated transcription;GO:0000724 double-strand break repair via homologous recombination", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1RSH5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SEV7-1", "uniprot_id": "F1SEV7_PIG", "mass": 53092.0, "length": 488, "protein_name": "Gasdermin D", "gene_name": "GSDMD", "organism": "Pig", "refseq_name": "gasdermin-D", "refseq_ac": "XP_020946163", "gene_names_uniprotkb": "GSDMD", "gene_names_refseq": "GSDMD", "protein_names_uniprotkb": "Gasdermin D", "protein_names_refseq": "gasdermin-D", "tax_id": 9823, "disease": "", "pathway": " (ssc:100515607); (R-SSC-111457); (R-SSC-111458); (R-SSC-111461); (R-SSC-448706); (R-SSC-5620971); (R-SSC-5686938); (R-SSC-6798695); (R-SSC-9960519); (R-SSC-9960525)", "pathway_count": 10, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005546 phosphatidylinositol-4,5-bisphosphate binding;GO:0070273 phosphatidylinositol-4-phosphate binding;GO:0001786 phosphatidylserine binding;GO:0070300 phosphatidic acid binding;GO:0022829 wide pore channel activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005886 plasma membrane;GO:0005615 extracellular space;GO:0005654 nucleoplasm;GO:0031966 mitochondrial membrane", "go_biological_process": "GO:0012501 programmed cell death;GO:0050829 defense response to Gram-negative bacterium;GO:0050830 defense response to Gram-positive bacterium;GO:0051260 protein homooligomerization;GO:0050729 positive regulation of inflammatory response", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SEV7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SGS6-1", "uniprot_id": "F1SGS6_PIG", "mass": 78256.0, "length": 709, "protein_name": "Cell cycle associated protein 1", "gene_name": "CAPRIN1", "organism": "Pig", "refseq_name": "caprin-1", "refseq_ac": "XP_005661078", "gene_names_uniprotkb": "CAPRIN1", "gene_names_refseq": "CAPRIN1", "protein_names_uniprotkb": "Cell cycle associated protein 1", "protein_names_refseq": "caprin-1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100512646)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A287BHR0", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding;GO:0003729 mRNA binding;GO:0005524 ATP binding;GO:0035591 signaling adaptor activity;GO:0140693 molecular condensate scaffold activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005829 cytosol;GO:0030425 dendrite;GO:0031252 cell leading edge;GO:0045202 synapse", "go_biological_process": "GO:0030154 cell differentiation;GO:0017148 negative regulation of translation;GO:0061003 positive regulation of dendritic spine morphogenesis;GO:0062029 positive regulation of stress granule assembly;GO:0140694 membraneless organelle assembly", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SGS6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1S8D4-1", "uniprot_id": "F1S8D4_PIG", "mass": 36975.0, "length": 342, "protein_name": "Methylosome protein WDR77", "gene_name": "WDR77", "organism": "Pig", "refseq_name": "methylosome protein 50 isoform X1", "refseq_ac": "XP_003355293", "gene_names_uniprotkb": "WDR77", "gene_names_refseq": "WDR77", "protein_names_uniprotkb": "Methylosome protein WDR77; Methylosome protein 50; WD repeat-containing protein 77", "protein_names_refseq": "methylosome protein 50 isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100156038); (R-SSC-191859); (R-SSC-3214858)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Non-catalytic component of the methylosome complex, composed of PRMT5, WDR77 and CLNS1A, which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins and histones. This modification targets Sm proteins to the survival of motor neurons (SMN) complex for assembly into small nuclear ribonucleoprotein core particles. Might play a role in transcription regulation. The methylosome complex also methylates the Piwi proteins (PIWIL1, PIWIL2 and PIWIL4), methylation of Piwi proteins being required for the interaction with Tudor domain-containing proteins and subsequent localization to the meiotic nuage., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003713 transcription coactivator activity;GO:0008327 methyl-CpG binding;GO:1990756 ubiquitin-like ligase-substrate adaptor activity", "go_cellular_component": "GO:1990234 transferase complex;GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0005654 nucleoplasm;GO:0005794 Golgi apparatus", "go_biological_process": "GO:0000209 protein polyubiquitination;GO:0006511 ubiquitin-dependent protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1S8D4-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1RUC1-1", "uniprot_id": "F1RUC1_PIG", "mass": 120215.0, "length": 1060, "protein_name": "Cullin-4B", "gene_name": "CUL4B", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "CUL4B", "gene_names_refseq": "", "protein_names_uniprotkb": "Cullin-4B", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-110314); (R-SSC-5696394); (R-SSC-5696395); (R-SSC-5696400); (R-SSC-6781823); (R-SSC-6782135); (R-SSC-6782210); (R-SSC-8951664)", "pathway_count": 8, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 2, "predicted_n_glycosites": 0, "predicted_o_glycosites": 2, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 2, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0031625 ubiquitin protein ligase binding;GO:0003684 damaged DNA binding;GO:0160072 ubiquitin ligase complex scaffold activity", "go_cellular_component": "GO:0031464 Cul4A-RING E3 ubiquitin ligase complex;GO:0005634 nucleus;GO:0005737 cytoplasm;GO:0031465 Cul4B-RING E3 ubiquitin ligase complex;GO:0031461 cullin-RING ubiquitin ligase complex", "go_biological_process": "GO:0006281 DNA repair;GO:0042254 ribosome biogenesis;GO:0016567 protein ubiquitination;GO:0006511 ubiquitin-dependent protein catabolic process;GO:0048708 astrocyte differentiation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1RUC1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1S939-1", "uniprot_id": "F1S939_PIG", "mass": 112598.0, "length": 1065, "protein_name": "Microtubule associated protein 1S", "gene_name": "MAP1S", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "MAP1S", "gene_names_refseq": "", "protein_names_uniprotkb": "Microtubule associated protein 1S", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008017 microtubule binding;GO:0003677 DNA binding;GO:0003779 actin binding;GO:0051015 actin filament binding;GO:0048487 beta-tubulin binding", "go_cellular_component": "GO:0005874 microtubule;GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0005813 centrosome;GO:0005829 cytosol", "go_biological_process": "GO:0007399 nervous system development;GO:0000226 microtubule cytoskeleton organization;GO:0051310 metaphase chromosome alignment;GO:0007409 axonogenesis;GO:0016358 dendrite development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1S939-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1RTA9-1", "uniprot_id": "F1RTA9_PIG", "mass": 58769.0, "length": 510, "protein_name": "25/26-hydroxycholesterol 7alpha-hydroxylase", "gene_name": "CYP7B1", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "CYP7B1", "gene_names_refseq": "", "protein_names_uniprotkb": "25/26-hydroxycholesterol 7alpha-hydroxylase; 1.14.14.29; Oxysterol 7-alpha-hydroxylase", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (ssc:100738003); (R-SSC-192105); (R-SSC-193368); (R-SSC-193807); (R-SSC-211976)", "pathway_count": 5, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005506 iron ion binding;GO:0020037 heme binding;GO:0033783 25-hydroxycholesterol 7-alpha-hydroxylase activity;GO:0004497 monooxygenase activity;GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen", "go_cellular_component": "GO:0005789 endoplasmic reticulum membrane", "go_biological_process": "GO:0008203 cholesterol metabolic process;GO:0008202 steroid metabolic process;GO:0006699 bile acid biosynthetic process;GO:0042632 cholesterol homeostasis;GO:0035754 B cell chemotaxis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1RTA9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1RY68-1", "uniprot_id": "F1RY68_PIG", "mass": 88094.0, "length": 771, "protein_name": "carnitine O-palmitoyltransferase", "gene_name": "CPT1A", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "CPT1A", "gene_names_refseq": "", "protein_names_uniprotkb": "carnitine O-palmitoyltransferase; 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BRG1-associated factor 53A", "protein_names_refseq": "actin-like protein 6A isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100523570); (R-SSC-3214858); (R-SSC-5689603); (R-SSC-8939243); (R-SSC-9933937); (R-SSC-9933939); (R-SSC-9933946); (R-SSC-9933947)", "pathway_count": 8, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003682 chromatin binding", "go_cellular_component": "GO:0005654 nucleoplasm;GO:0016514 SWI/SNF complex;GO:0071564 npBAF complex;GO:0005886 plasma membrane;GO:0031011 Ino80 complex", "go_biological_process": "GO:0033044 regulation of chromosome organization;GO:0006281 DNA repair;GO:0006310 DNA recombination;GO:0006338 chromatin remodeling;GO:0006351 DNA-templated transcription", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SGC8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1RYM5-1", "uniprot_id": "F1RYM5_PIG", "mass": 77132.0, "length": 694, "protein_name": "Signal peptide peptidase-like 2A", "gene_name": "SPPL2A", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "SPPL2A", "gene_names_refseq": "", "protein_names_uniprotkb": "Signal peptide peptidase-like 2A; Intramembrane protease 3; Presenilin-like protein 2", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (ssc:100522175); (R-SSC-5357905)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0042500 aspartic endopeptidase activity, intramembrane cleaving;GO:0042803 protein homodimerization activity", "go_cellular_component": "GO:0012505 endomembrane system;GO:0031090 organelle membrane;GO:0005765 lysosomal membrane;GO:0031902 late endosome membrane;GO:0098554 cytoplasmic side of endoplasmic reticulum membrane", "go_biological_process": "GO:0050776 regulation of immune response;GO:0033619 membrane protein proteolysis;GO:0006509 membrane protein ectodomain proteolysis;GO:0031293 membrane protein intracellular domain proteolysis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1RYM5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SBM1-1", "uniprot_id": "F1SBM1_PIG", "mass": 92761.0, "length": 831, "protein_name": "DNA helicase MCM8", "gene_name": "MCM8", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "MCM8", "gene_names_refseq": "", "protein_names_uniprotkb": "DNA helicase MCM8; 5.6.2.4; DNA 3'-5' helicase MCM8; Minichromosome maintenance 8", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-176187); (R-SSC-68689); (R-SSC-68949); (R-SSC-68962)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0005524 ATP binding;GO:0016787 hydrolase activity;GO:0003678 DNA helicase activity;GO:0043138 3'-5' DNA helicase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005694 chromosome;GO:0097362 MCM8-MCM9 complex;GO:0005654 nucleoplasm;GO:0042555 MCM complex", "go_biological_process": "GO:0006260 DNA replication;GO:0000724 double-strand break repair via homologous recombination;GO:0050821 protein stabilization;GO:0007292 female gamete generation;GO:0071168 protein localization to chromatin", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SBM1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SGE7-1", "uniprot_id": "F1SGE7_PIG", "mass": 87477.0, "length": 800, "protein_name": "Integrin beta", "gene_name": "ITGB7", "organism": "Pig", "refseq_name": "integrin beta-7 isoform X1", "refseq_ac": "XP_003355464", "gene_names_uniprotkb": "ITGB7", "gene_names_refseq": "ITGB7", "protein_names_uniprotkb": "Integrin beta", "protein_names_refseq": "integrin beta-7 isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:397221); (R-SSC-198933); (R-SSC-216083)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Integrin ITGA4/ITGB7 (alpha-4/beta-7) (Peyer patches-specific homing receptor LPAM-1) is an adhesion molecule that mediates lymphocyte migration and homing to gut-associated lymphoid tissue (GALT). Integrin ITGA4/ITGB7 interacts with the cell surface adhesion molecules MADCAM1 which is normally expressed by the vascular endothelium of the gastrointestinal tract. Also interacts with VCAM1 and fibronectin, an extracellular matrix component. It recognizes one or more domains within the alternatively spliced CS-1 region of fibronectin. Interactions involve the tripeptide L-D-T in MADCAM1, and L-D-V in fibronectin. Integrin ITGAE/ITGB7 (alpha-E/beta-7, HML-1) is a receptor for E-cadherin., [UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0046872 metal ion binding;GO:0005178 integrin binding;GO:0050839 cell adhesion molecule binding", "go_cellular_component": "GO:0005886 plasma membrane;GO:0005925 focal adhesion;GO:0009986 cell surface;GO:0008305 integrin complex;GO:0034669 integrin alpha4-beta7 complex", "go_biological_process": "GO:0007155 cell adhesion;GO:0007229 integrin-mediated signaling pathway;GO:0007160 cell-matrix adhesion;GO:0033627 cell adhesion mediated by integrin;GO:0098609 cell-cell adhesion", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SGE7-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1S8S0-1", "uniprot_id": "F1S8S0_PIG", "mass": 116450.0, "length": 1069, "protein_name": "Histone-lysine N-methyltransferase NSD2", "gene_name": "NSD2", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "NSD2", "gene_names_refseq": "", "protein_names_uniprotkb": "Histone-lysine N-methyltransferase NSD2; 2.1.1.357; Multiple myeloma SET domain-containing protein; Nuclear SET domain-containing protein 2", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-3214841); (R-SSC-5693565); (R-SSC-5693571); (R-SSC-5693607); (R-SSC-69473)", "pathway_count": 5, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003677 DNA binding;GO:0003682 chromatin binding;GO:0008270 zinc ion binding;GO:0043565 sequence-specific DNA binding;GO:0046975 histone H3K36 methyltransferase activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005654 nucleoplasm;GO:0005730 nucleolus;GO:0000785 chromatin", "go_biological_process": "GO:0006355 regulation of DNA-templated transcription;GO:0032259 methylation", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1S8S0-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1S8A3-1", "uniprot_id": "F1S8A3_PIG", "mass": 92075.0, "length": 815, "protein_name": "Vacuolar protein sorting-associated protein 16 homolog", "gene_name": "VPS16", "organism": "Pig", "refseq_name": "vacuolar protein sorting-associated protein 16 homolog isoform X2", "refseq_ac": "XP_013840614", "gene_names_uniprotkb": "VPS16", "gene_names_refseq": "VPS16", "protein_names_uniprotkb": "Vacuolar protein sorting-associated protein 16 homolog", "protein_names_refseq": "vacuolar protein sorting-associated protein 16 homolog isoform X2", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0060090 molecular adaptor activity;GO:0003779 actin binding", "go_cellular_component": "GO:0030897 HOPS complex;GO:0005769 early endosome;GO:0005765 lysosomal membrane;GO:0031902 late endosome membrane;GO:0033263 CORVET complex", "go_biological_process": "GO:0006886 intracellular protein transport;GO:0007033 vacuole organization;GO:0097352 autophagosome maturation;GO:0042144 vacuole fusion, non-autophagic;GO:0008333 endosome to lysosome transport", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1S8A3-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1RW83-1", "uniprot_id": "F1RW83_PIG", "mass": 86231.0, "length": 762, "protein_name": "Protein artemis", "gene_name": "DCLRE1C", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "DCLRE1C", "gene_names_refseq": "", "protein_names_uniprotkb": "Protein artemis; DNA cross-link repair 1C protein", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-5693571)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004519 endonuclease activity;GO:0004527 exonuclease activity;GO:0003684 damaged DNA binding;GO:0000014 single-stranded DNA endodeoxyribonuclease activity;GO:0035312 5'-3' DNA exonuclease activity", "go_cellular_component": "GO:0005634 nucleus;GO:0070419 nonhomologous end joining complex;GO:0005654 nucleoplasm", "go_biological_process": "GO:0006281 DNA repair;GO:0006310 DNA recombination;GO:0000723 telomere maintenance;GO:0006303 double-strand break repair via nonhomologous end joining;GO:0036297 interstrand cross-link repair", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1RW83-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SGH9-1", "uniprot_id": "F1SGH9_PIG", "mass": 76791.0, "length": 681, "protein_name": "Acyl-coenzyme A oxidase", "gene_name": "ACOX2", "organism": "Pig", "refseq_name": "peroxisomal acyl-coenzyme A oxidase 2 isoform X1", "refseq_ac": "XP_003132329", "gene_names_uniprotkb": "ACOX2", "gene_names_refseq": "ACOX2", "protein_names_uniprotkb": "Acyl-coenzyme A oxidase", "protein_names_refseq": "peroxisomal acyl-coenzyme A oxidase 2 isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100516877); (R-SSC-193368); (R-SSC-389887); (R-SSC-9033241)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0071949 FAD binding;GO:0003997 acyl-CoA oxidase activity;GO:0005504 fatty acid binding;GO:0050660 flavin adenine dinucleotide binding;GO:0033791 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase activity", "go_cellular_component": "GO:0005777 peroxisome", "go_biological_process": "GO:0006635 fatty acid beta-oxidation;GO:0000038 very long-chain fatty acid metabolic process;GO:0006699 bile acid biosynthetic process;GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SGH9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1RZ92-1", "uniprot_id": "F1RZ92_PIG", "mass": 106523.0, "length": 965, "protein_name": "Proprotein convertase subtilisin/kexin type 6", "gene_name": "PCSK6", "organism": "Pig", "refseq_name": "proprotein convertase subtilisin/kexin type 6 isoform X2", "refseq_ac": "XP_020954598", "gene_names_uniprotkb": "PCSK6", "gene_names_refseq": "PCSK6", "protein_names_uniprotkb": "Proprotein convertase subtilisin/kexin type 6; Paired basic amino acid cleaving enzyme 4; Subtilisin-like proprotein convertase 4; Subtilisin/kexin-like protease PACE4", "protein_names_refseq": "proprotein convertase subtilisin/kexin type 6 isoform X2", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-167060); (R-SSC-6809371); (R-SSC-8963889); (R-SSC-9768727)", "pathway_count": 4, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Serine endoprotease that processes various proproteins by cleavage at paired basic amino acids, recognizing the RXXX[KR]R consensus motif. Likely functions in the constitutive secretory pathway, with unique restricted distribution in both neuroendocrine and non-neuroendocrine tissues., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0004252 serine-type endopeptidase activity;GO:0048406 nerve growth factor binding;GO:0008201 heparin binding", "go_cellular_component": "GO:0005615 extracellular space;GO:0009986 cell surface;GO:0016020 membrane;GO:0031012 extracellular matrix", "go_biological_process": "GO:0016486 peptide hormone processing;GO:0006508 proteolysis;GO:0032902 nerve growth factor production;GO:0032940 secretion by cell;GO:0009100 glycoprotein metabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1RZ92-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SIC1-1", "uniprot_id": "F1SIC1_PIG", "mass": 47982.0, "length": 427, "protein_name": "DNA damage-binding protein 2", "gene_name": "DDB2", "organism": "Pig", "refseq_name": "DNA damage-binding protein 2 isoform X2", "refseq_ac": "XP_003122861", "gene_names_uniprotkb": "DDB2", "gene_names_refseq": "DDB2", "protein_names_uniprotkb": "DNA damage-binding protein 2; Damage-specific DNA-binding protein 2", "protein_names_refseq": "DNA damage-binding protein 2 isoform X2", "tax_id": 9823, "disease": "", "pathway": " (ssc:100513197); (R-SSC-5689880); (R-SSC-5696394); (R-SSC-5696395); (R-SSC-5696400); (R-SSC-8951664)", "pathway_count": 6, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003684 damaged DNA binding;GO:0044877 protein-containing complex binding;GO:0004842 ubiquitin-protein transferase activity", "go_cellular_component": "GO:0031464 Cul4A-RING E3 ubiquitin ligase complex;GO:0005634 nucleus;GO:0005694 chromosome;GO:0080008 Cul4-RING E3 ubiquitin ligase complex;GO:0005654 nucleoplasm", "go_biological_process": "GO:0006281 DNA repair;GO:0034644 cellular response to UV;GO:0009411 response to UV;GO:0000209 protein polyubiquitination;GO:0051865 protein autoubiquitination", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SIC1-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1RZ24-1", "uniprot_id": "F1RZ24_PIG", "mass": 58171.0, "length": 521, "protein_name": "H/ACA ribonucleoprotein complex subunit DKC1", "gene_name": "DKC1", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "DKC1", "gene_names_refseq": "", "protein_names_uniprotkb": "H/ACA ribonucleoprotein complex subunit DKC1; Dyskerin; Nopp140-associated protein of 57 kDa; Nucleolar protein NAP57; Nucleolar protein family A member 4; snoRNP protein DKC1", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-171319); (R-SSC-174430)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Catalytic subunit of H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to 100 pseudouridine ('psi') residues, which may serve to stabilize the conformation of rRNAs. Required for ribosome biogenesis and telomere maintenance. Also required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse transcriptase (TERT) holoenzyme., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003723 RNA binding;GO:0009982 pseudouridine synthase activity;GO:0003720 telomerase activity;GO:0034513 box H/ACA snoRNA binding;GO:0070034 telomerase RNA binding", "go_cellular_component": "GO:0015030 Cajal body;GO:0001650 fibrillar center;GO:0031429 box H/ACA snoRNP complex;GO:0090661 box H/ACA telomerase RNP complex", "go_biological_process": "GO:0031118 rRNA pseudouridine synthesis;GO:0000455 enzyme-directed rRNA pseudouridine synthesis;GO:0000495 box H/ACA sno(s)RNA 3'-end processing;GO:0031120 snRNA pseudouridine synthesis;GO:1904874 positive regulation of telomerase RNA localization to Cajal body", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1RZ24-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SD91-1", "uniprot_id": "F1SD91_PIG", "mass": 222743.0, "length": 1987, "protein_name": "Coiled-coil domain containing 88C", "gene_name": "CCDC88C", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "CCDC88C", "gene_names_refseq": "", "protein_names_uniprotkb": "Coiled-coil domain containing 88C", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 4, "predicted_n_glycosites": 0, "predicted_o_glycosites": 4, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 4, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005109 frizzled binding;GO:0008017 microtubule binding;GO:0046983 protein dimerization activity;GO:0001965 G-protein alpha-subunit binding;GO:0005085 guanyl-nucleotide exchange factor activity", "go_cellular_component": "GO:0005737 cytoplasm;GO:0005813 centrosome;GO:0043296 apical junction complex", "go_biological_process": "GO:0030705 cytoskeleton-dependent intracellular transport;GO:0090090 negative regulation of canonical Wnt signaling pathway;GO:0007264 small GTPase-mediated signal transduction;GO:0031648 protein destabilization;GO:0035567 non-canonical Wnt signaling pathway", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SD91-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1S880-1", "uniprot_id": "F1S880_PIG", "mass": 40571.0, "length": 370, "protein_name": "NSFL1 cofactor p47", "gene_name": "NSFL1C", "organism": "Pig", "refseq_name": "NSFL1 cofactor p47", "refseq_ac": "NP_001231372", "gene_names_uniprotkb": "NSFL1C", "gene_names_refseq": "NSFL1C", "protein_names_uniprotkb": "NSFL1 cofactor p47; p97 cofactor p47", "protein_names_refseq": "NSFL1 (p97) cofactor (p47); NSFL1 cofactor p47", "tax_id": 9823, "disease": "", "pathway": " (ssc:100513186); (R-SSC-9013407)", "pathway_count": 2, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0008289 lipid binding;GO:0043130 ubiquitin binding", "go_cellular_component": "GO:1990730 VCP-NSFL1C complex;GO:0005634 nucleus;GO:0005813 centrosome;GO:0005795 Golgi stack;GO:0005829 cytosol", "go_biological_process": "GO:0000132 establishment of mitotic spindle orientation;GO:0046604 positive regulation of mitotic centrosome separation;GO:1904780 negative regulation of protein localization to centrosome;GO:0031468 nuclear membrane reassembly;GO:0000045 autophagosome assembly", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1S880-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SDW9-1", "uniprot_id": "F1SDW9_PIG", "mass": 63733.0, "length": 568, "protein_name": "Protein phosphatase 1 regulatory inhibitor subunit 16B", "gene_name": "PPP1R16B", "organism": "Pig", "refseq_name": "protein phosphatase 1 regulatory inhibitor subunit 16B isoform X1", "refseq_ac": "XP_003134487", "gene_names_uniprotkb": "PPP1R16B", "gene_names_refseq": "PPP1R16B", "protein_names_uniprotkb": "Protein phosphatase 1 regulatory inhibitor subunit 16B; CAAX box protein TIMAP; TGF-beta-inhibited membrane-associated protein", "protein_names_refseq": "protein phosphatase 1 regulatory inhibitor subunit 16B isoform X1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100517865)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 1, "predicted_n_glycosites": 0, "predicted_o_glycosites": 1, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 1, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0019888 protein phosphatase regulator activity;GO:0017020 myosin phosphatase regulator activity;GO:0004857 enzyme inhibitor activity", "go_cellular_component": "GO:0005634 nucleus;GO:0005886 plasma membrane;GO:0042995 cell projection;GO:0005737 cytoplasm;GO:0016607 nuclear speck", "go_biological_process": "GO:0051896 regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction;GO:0061028 establishment of endothelial barrier;GO:1903670 regulation of sprouting angiogenesis;GO:1903589 positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SDW9-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SID5-1", "uniprot_id": "F1SID5_PIG", "mass": 39095.0, "length": 372, "protein_name": "Zinc transporter ZIP13", "gene_name": "SLC39A13", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "SLC39A13", "gene_names_refseq": "", "protein_names_uniprotkb": "Zinc transporter ZIP13; Solute carrier family 39 member 13; Zrt- and Irt-like protein 13", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Functions as a zinc transporter transporting Zn(2+) from the Golgi apparatus to the cytosol and thus influences the zinc level at least in areas of the cytosol. May regulate beige adipocyte differentiation., [UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0046873 metal ion transmembrane transporter activity;GO:0005385 zinc ion transmembrane transporter activity;GO:0042803 protein homodimerization activity", "go_cellular_component": "GO:0000139 Golgi membrane;GO:0048471 perinuclear region of cytoplasm;GO:0005789 endoplasmic reticulum membrane;GO:0030659 cytoplasmic vesicle membrane", "go_biological_process": "GO:0006829 zinc ion transport;GO:0071577 zinc ion transmembrane transport;GO:0050873 brown fat cell differentiation;GO:0006882 intracellular zinc ion homeostasis;GO:0061448 connective tissue development", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SID5-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1SFP6-1", "uniprot_id": "F1SFP6_PIG", "mass": 123199.0, "length": 1096, "protein_name": "TATA element modulatory factor 1", "gene_name": "TMF1", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "TMF1", "gene_names_refseq": "", "protein_names_uniprotkb": "TATA element modulatory factor 1", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-6811440)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0003713 transcription coactivator activity;GO:0050681 nuclear androgen receptor binding", "go_cellular_component": "GO:0005794 Golgi apparatus;GO:0005783 endoplasmic reticulum", "go_biological_process": "GO:0045944 positive regulation of transcription by RNA polymerase II;GO:0030521 androgen receptor signaling pathway;GO:0061136 regulation of proteasomal protein catabolic process", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1SFP6-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1S2H2-1", "uniprot_id": "F1S2H2_PIG", "mass": 36351.0, "length": 322, "protein_name": "Corticotropin-releasing factor-binding protein", "gene_name": "CRHBP", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "CRHBP", "gene_names_refseq": "", "protein_names_uniprotkb": "Corticotropin-releasing factor-binding protein; CRF-BP; CRF-binding protein; Corticotropin-releasing hormone-binding protein", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-373080)", "pathway_count": 1, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy., [UniProtKB, UniProtKB, UniProtKB, UniProtKB]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0051424 corticotropin-releasing hormone binding", "go_cellular_component": "GO:0005576 extracellular region;GO:0005615 extracellular space;GO:0005634 nucleus;GO:0030141 secretory granule;GO:0045202 synapse", "go_biological_process": "GO:0002125 maternal aggressive behavior;GO:0006954 inflammatory response;GO:0045055 regulated exocytosis;GO:0071320 cellular response to cAMP;GO:0001963 synaptic transmission, dopaminergic", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1S2H2-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1S5A8-1", "uniprot_id": "F1S5A8_PIG", "mass": 90933.0, "length": 795, "protein_name": "ATP-dependent RNA helicase DHX15", "gene_name": "DHX15", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "DHX15", "gene_names_refseq": "", "protein_names_uniprotkb": "ATP-dependent RNA helicase DHX15; 3.6.4.13; DEAH box protein 15", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": " (R-SSC-72163); (R-SSC-9770562); (R-SSC-9943411)", "pathway_count": 3, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A4X1VCA4", "ec_number_list": "", "go_molecular_function": "GO:0005524 ATP binding;GO:0016787 hydrolase activity;GO:0003676 nucleic acid binding;GO:0003724 RNA helicase activity;GO:0003723 RNA binding", "go_cellular_component": "GO:0005634 nucleus;GO:0016607 nuclear speck;GO:0005681 spliceosomal complex;GO:0071008 U2-type post-mRNA release spliceosomal complex;GO:0005689 U12-type spliceosomal complex", "go_biological_process": "GO:0006397 mRNA processing;GO:0008380 RNA splicing;GO:0140374 antiviral innate immune response;GO:0043123 positive regulation of canonical NF-kappaB signal transduction;GO:0042742 defense response to bacterium", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1S5A8-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1S340-1", "uniprot_id": "F1S340_PIG", "mass": 21733.0, "length": 199, "protein_name": "Sorcin", "gene_name": "SRI", "organism": "Pig", "refseq_name": "sorcin isoform 1", "refseq_ac": "NP_001231071", "gene_names_uniprotkb": "SRI", "gene_names_refseq": "SRI", "protein_names_uniprotkb": "Sorcin", "protein_names_refseq": "sorcin isoform 1", "tax_id": 9823, "disease": "", "pathway": " (ssc:100514123); (R-SSC-2672351); (R-SSC-418359); (R-SSC-425561); (R-SSC-5578775); (R-SSC-936837)", "pathway_count": 6, "publication_count": 2, "publication_id_list": "23764275;32543654", "class_list": "", "function": "Foot-and-mouth disease virus VP1 as an interferon-suppressor by interacting with sorcin., [RefSeq, PubMed]", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "", "ec_number_list": "", "go_molecular_function": "GO:0005509 calcium ion binding;GO:0002020 protease binding;GO:0046982 protein heterodimerization activity;GO:0140416 transcription regulator inhibitor activity;GO:0140297 DNA-binding transcription factor binding", "go_cellular_component": "GO:0005737 cytoplasm;GO:0012505 endomembrane system;GO:0005829 cytosol;GO:0005886 plasma membrane;GO:0070062 extracellular exosome", "go_biological_process": "GO:0055118 negative regulation of cardiac muscle contraction;GO:0010459 negative regulation of heart rate;GO:0051281 positive regulation of release of sequestered calcium ion into cytosol;GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus;GO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum", "synthesized_glycan_count": 0, "hit_score": 0.3, "record_id": "F1S340-1", "record_type": "protein" }, { "uniprot_canonical_ac": "F1RWZ2-1", "uniprot_id": "F1RWZ2_PIG", "mass": 120422.0, "length": 1040, "protein_name": "Serine/threonine-protein kinase PRP4 homolog", "gene_name": "PRP4K", "organism": "Pig", "refseq_name": "", "refseq_ac": "", "gene_names_uniprotkb": "PRP4K", "gene_names_refseq": "", "protein_names_uniprotkb": "Serine/threonine-protein kinase PRP4 homolog; 2.7.11.1; PRP4 pre-mRNA-processing factor 4 homolog", "protein_names_refseq": "", "tax_id": 9823, "disease": "", "pathway": "", "pathway_count": 0, "publication_count": 1, "publication_id_list": "32543654", "class_list": "", "function": "", "predicted_glycosites": 0, "predicted_n_glycosites": 0, "predicted_o_glycosites": 0, "predicted_c_glycosites": 0, "predicted_s_glycosites": 0, "mined_glycosites": 0, "mined_n_glycosites": 0, "mined_o_glycosites": 0, "mined_c_glycosites": 0, "mined_s_glycosites": 0, "reported_n_glycosites": 0, "reported_o_glycosites": 0, "reported_c_glycosites": 0, "reported_s_glycosites": 0, "reported_n_glycosites_with_glycan": 0, "reported_o_glycosites_with_glycan": 0, "reported_c_glycosites_with_glycan": 0, "reported_s_glycosites_with_glycan": 0, "total_reported_n_glycosites": 0, "total_reported_o_glycosites": 0, "total_reported_c_glycosites": 0, "total_reported_s_glycosites": 0, "total_n_glycosites": 0, "total_o_glycosites": 0, "total_c_glycosites": 0, "total_s_glycosites": 0, "reported_fully_resolved_glycans": 0, "reported_phosphosites": 0, "reported_mutagensis": 0, "reported_glycation": 0, "reported_snv": 0, "reported_interactions": 0, "missing_score": 10000, "biomarker_type": "", "glycan_count": 0, "disease_count": 0, "glyco_site_count": 0, "binding_glycan_count": 0, "secondary_ac_list": "A0A287A6U9", "ec_number_list": "", "go_molecular_function": "GO:0004674 protein serine/threonine kinase activity;GO:0005524 ATP binding", "go_cellular_component": "GO:0005681 spliceosomal complex;GO:0000776 kinetochore;GO:0005634 nucleus;GO:0016607 nuclear speck;GO:0071013 catalytic step 2 spliceosome", "go_biological_process": "GO:0045292 mRNA cis splicing, via spliceosome;GO:0000244 spliceosomal tri-snRNP complex assembly;GO:0046827 positive regulation of protein export from nucleus;GO:0090266 regulation of mitotic cell cycle spindle assembly checkpoint;GO:0035332 positive regulation of hippo signaling", "synthesized_glycan_count": 0, "hit_score": 0.2, "record_id": "F1RWZ2-1", "record_type": "protein" } ]