{
    "disease_id": "DOID:0110782",
    "recommended_name": {
        "id": "DOID:0110782",
        "resource": "Disease Ontology",
        "url": "https://disease-ontology.org/term/DOID:0110782",
        "name": "hereditary spastic paraplegia 31",
        "description": "A hereditary spastic paraplegia that has_material_basis_in mutation in the REEP1 gene on chromosome 2p11."
    },
    "synonyms": [
        {
            "id": "DOID:0110782",
            "resource": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0110782",
            "name": "SPG31",
            "description": ""
        },
        {
            "id": "DOID:0110782",
            "resource": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0110782",
            "name": "autosomal dominant spastic paraplegia 31",
            "description": ""
        },
        {
            "id": "DOID:0110782",
            "resource": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:0110782",
            "name": "autosomal dominant spastic paraplegia type 31",
            "description": ""
        },
        {
            "id": "MONDO:0012453",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0012453",
            "name": "hereditary spastic paraplegia 31",
            "description": "A rare type of hereditary spastic paraplegia usually characterized by a pure phenotype of proximal weakness of the lower extremities with spastic gait and brisk reflexes, with a bimodal age of onset of either childhood or adulthood (>30 years). In some cases, it can present as a complex phenotype with additional associated manifestations including peripheral neuropathy, bulbar palsy (with dysarthria and dysphagia), distal amyotrophy, and impaired distal vibration sense."
        },
        {
            "id": "MONDO:0012453",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0012453",
            "name": "REEP1 hereditary spastic paraplegia",
            "description": ""
        },
        {
            "id": "MONDO:0012453",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0012453",
            "name": "SPG31",
            "description": ""
        },
        {
            "id": "MONDO:0012453",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0012453",
            "name": "autosomal dominant spastic paraplegia type 31",
            "description": ""
        },
        {
            "id": "MONDO:0012453",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0012453",
            "name": "hereditary spastic paraplegia caused by mutation in REEP1",
            "description": ""
        },
        {
            "id": "MONDO:0012453",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0012453",
            "name": "hereditary spastic paraplegia type 31",
            "description": ""
        },
        {
            "id": "MONDO:0012453",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0012453",
            "name": "spastic paraplegia 31",
            "description": ""
        },
        {
            "id": "MONDO:0012453",
            "resource": "MONDO",
            "url": "https://monarchinitiative.org/disease/MONDO:0012453",
            "name": "spastic paraplegia 31, autosomal dominant",
            "description": ""
        },
        {
            "id": "MIM:610250",
            "resource": "MIM",
            "url": "https://www.omim.org/entry/610250",
            "name": "Spastic paraplegia 31, autosomal dominant",
            "description": "Spastic paraplegia 31, autosomal dominant"
        }
    ],
    "children": [],
    "id_list": [
        "DOID:0110782"
    ],
    "unlinked_id_list": []
}