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mediated degradation", "degradation of nek2a", "apc cdc20 mediated degradation", "cdc20 mediated degradation of", "mediated degradation of nek2a", "apc cdc20 mediated degradation of", "cdc20 mediated degradation of nek2a", "srp", "cotranslational", "protein", "targeting", "to", "membrane", "srp dependent", "dependent cotranslational", "cotranslational protein", "protein targeting", "targeting to", "to membrane", "srp dependent cotranslational", "dependent cotranslational protein", "cotranslational protein targeting", "protein targeting to", "targeting to membrane", "srp dependent cotranslational protein", "dependent cotranslational protein targeting", "cotranslational protein targeting to", "protein targeting to membrane", "srp dependent cotranslational protein targeting", "dependent cotranslational protein targeting to", "cotranslational protein targeting to membrane", "egfr", "egfr downregulation", "skp2", "p27/p21", "scf skp2", "of p27/p21", "skp2 mediated", "degradation of p27/p21", "scf skp2 mediated", "skp2 mediated degradation", "mediated degradation of p27/p21", "scf skp2 mediated degradation", "skp2 mediated degradation of", "catenin", "the", "destruction", "of beta", "beta catenin", "catenin by", "by the", "the destruction", "destruction complex", "degradation of beta", "of beta catenin", "beta catenin by", "catenin by the", "by the destruction", "the destruction complex", "degradation of beta catenin", "of beta catenin by", "beta catenin by the", "catenin by the destruction", "by the destruction complex", "degradation of beta catenin by", "of beta catenin by the", "beta catenin by the destruction", "catenin by the destruction complex", "p75ntr", "recruits", "signalling", "complexes", "p75ntr recruits", "recruits signalling", "signalling complexes", "p75ntr recruits signalling", "recruits signalling complexes", "p75ntr recruits signalling complexes", "kb", "is", "activated", "signals", "survival", "nf kb", "kb is", "is activated", "activated and", "and signals", "signals survival", "nf kb is", "kb is activated", "is activated and", "activated and signals", "and signals survival", "nf kb is activated", "kb is activated and", "is activated and signals", "activated and signals survival", "nf kb is activated and", "kb is activated and signals", "is activated and signals survival", "notch1", "transmits", "signal", "nucleus", "activated notch1", "notch1 transmits", "transmits signal", "signal to", "to the", "the nucleus", "activated notch1 transmits", "notch1 transmits signal", "transmits signal to", "signal to the", "to the nucleus", "activated notch1 transmits signal", "notch1 transmits signal to", "transmits signal to the", "signal to the nucleus", "activated notch1 transmits signal to", "notch1 transmits signal to the", "transmits signal to the nucleus", "tgf", "receptor", "of tgf", "tgf beta", "beta receptor", "receptor signaling", "downregulation of tgf", "of tgf beta", "tgf beta receptor", "beta receptor signaling", "downregulation of tgf beta", "of tgf beta receptor", "tgf beta receptor signaling", "downregulation of tgf beta receptor", "of tgf beta receptor signaling", "emt", "epithelial", "mesenchymal", "transition", "signaling in", "in emt", "epithelial to", "to mesenchymal", "mesenchymal transition", "receptor signaling in", "signaling in emt", "emt epithelial", "epithelial to mesenchymal", "to mesenchymal transition", "beta receptor signaling in", "receptor signaling in emt", "in emt epithelial", "emt epithelial to", "epithelial to mesenchymal transition", "tgf beta receptor signaling in", "beta receptor signaling in emt", "signaling in emt epithelial", "in emt epithelial to", "emt epithelial to mesenchymal", "smad2/3:smad4", "transcriptional", "activity", "of smad2/3:smad4", "smad2/3:smad4 transcriptional", "transcriptional activity", "downregulation of smad2/3:smad4", "of smad2/3:smad4 transcriptional", "smad2/3:smad4 transcriptional activity", "downregulation of smad2/3:smad4 transcriptional", "of smad2/3:smad4 transcriptional activity", "downregulation of smad2/3:smad4 transcriptional activity", "smad2/smad3:smad4", "heterotrimer", "regulates", "transcription", "smad2/smad3:smad4 heterotrimer", "heterotrimer regulates", "regulates transcription", "smad2/smad3:smad4 heterotrimer regulates", "heterotrimer regulates transcription", "smad2/smad3:smad4 heterotrimer regulates transcription", "separation", "sister", "chromatids", "separation of", "of sister", "sister chromatids", "separation of sister", "of sister chromatids", "separation of sister chromatids", "oxidative", "stress", "induced", "senescence", "oxidative stress", "stress induced", "induced senescence", "oxidative stress induced", "stress induced senescence", "oxidative stress induced senescence", "associated", "secretory", "phenotype", "sasp", "senescence associated", "associated secretory", "secretory phenotype", "senescence associated secretory", "associated secretory phenotype", "phenotype sasp", "senescence associated secretory phenotype", "secretory phenotype sasp", "associated secretory phenotype sasp", "oncogene", "oncogene induced", "oncogene induced senescence", "plk1", "at", "g2/m", "of plk1", "plk1 activity", "activity at", "at g2/m", "g2/m transition", "regulation of plk1", "of plk1 activity", "plk1 activity at", "activity at g2/m", "at g2/m transition", "regulation of plk1 activity", "of plk1 activity at", "plk1 activity at g2/m", "activity at g2/m transition", "regulation of plk1 activity at", "of plk1 activity at g2/m", "plk1 activity at g2/m transition", "innate", "immune", "responses", "cytosolic", "of innate", "innate immune", "immune responses", "responses to", "to cytosolic", "cytosolic dna", "regulation of innate", "of innate immune", "innate immune responses", "immune responses to", "responses to cytosolic", "to cytosolic dna", "regulation of innate immune", "of innate immune responses", "innate immune responses to", "immune responses to cytosolic", "responses to cytosolic dna", "regulation of innate immune responses", "of innate immune responses to", "innate immune responses to cytosolic", "immune responses to cytosolic dna", "e3", "ubiquitin", "ligase", "cop1", "of the", "the e3", "e3 ubiquitin", "ubiquitin ligase", "ligase cop1", "autodegradation of the", "of the e3", "the e3 ubiquitin", "e3 ubiquitin ligase", "ubiquitin ligase cop1", "autodegradation of the e3", "of the e3 ubiquitin", "the e3 ubiquitin ligase", "e3 ubiquitin ligase cop1", "autodegradation of the e3 ubiquitin", "of the e3 ubiquitin ligase", "the e3 ubiquitin ligase cop1", "deactivation", "transactivating", "deactivation of", "the beta", "catenin transactivating", "transactivating complex", "deactivation of the", "of the beta", "the beta catenin", "beta catenin transactivating", "catenin transactivating complex", "deactivation of the beta", "of the beta catenin", "the beta catenin transactivating", "beta catenin transactivating complex", "deactivation of the beta catenin", "of the beta catenin transactivating", "the beta catenin transactivating complex", "abc", "family", "transport", "abc family", "family protein", "protein mediated", "mediated transport", "abc family protein", "family protein mediated", "protein mediated transport", "abc family protein mediated", "family protein mediated transport", "abc family protein mediated transport", "tak1", "ikk", "kappa", "tak1 dependent", "dependent ikk", "ikk and", "and nf", "nf kappa", "kappa b", "b activation", "tak1 dependent ikk", "dependent ikk and", "ikk and nf", "and nf kappa", "nf kappa b", "kappa b activation", "tak1 dependent ikk and", "dependent ikk and nf", "ikk and nf kappa", "and nf kappa b", "nf kappa b activation", "tak1 dependent ikk and nf", "dependent ikk and nf kappa", "ikk and nf kappa b", "and nf kappa b activation", "mediates", "p38", "mapk", "activated tak1", "tak1 mediates", "mediates p38", "p38 mapk", "mapk activation", "activated tak1 mediates", "tak1 mediates p38", "mediates p38 mapk", "p38 mapk activation", "activated tak1 mediates p38", "tak1 mediates p38 mapk", "mediates p38 mapk activation", "activated tak1 mediates p38 mapk", "tak1 mediates p38 mapk activation", "jnk", "jun", "kinases", "phosphorylation", "human", "c jun", "jun kinases", "phosphorylation and", "activation mediated", "mediated by", "by activated", "activated human", "human tak1", "jnk c", "c jun kinases", "kinases phosphorylation", "and activation", "activation mediated by", "mediated by activated", "by activated human", "activated human tak1", "jnk c jun", "jun kinases phosphorylation", "kinases phosphorylation and", "phosphorylation and activation", "and activation mediated", "activation mediated by activated", "mediated by activated human", "by activated human tak1", "jnk c jun kinases", "c jun kinases phosphorylation", "jun kinases phosphorylation and", "phosphorylation and activation mediated", "and activation mediated by", "activation mediated by activated human", "mediated by activated human tak1", "auf1", "hnrnp", "d0", "binds", "destabilizes", "mrna", "hnrnp d0", "binds and", "and destabilizes", "destabilizes mrna", "auf1 hnrnp", "d0 binds", "binds and destabilizes", "and destabilizes mrna", "auf1 hnrnp d0", "hnrnp d0 binds", "d0 binds and", "binds and destabilizes mrna", "hnrnp d0 binds and", "d0 binds and destabilizes", "asymmetric", "localization", "pcp", "asymmetric localization", "localization of", "of pcp", "pcp proteins", "asymmetric localization of", "localization of pcp", "of pcp proteins", "asymmetric localization of pcp", "localization of pcp proteins", "asymmetric localization of pcp proteins", "axin", "of axin", "degradation of axin", "dvl", "of dvl", "degradation of dvl", "fzd", "ubiquitination", "of fzd", "fzd by", "by ubiquitination", "regulation of fzd", "of fzd by", "fzd by ubiquitination", "regulation of fzd by", "of fzd by ubiquitination", "regulation of fzd by ubiquitination", "pink1", "prkn", "mitophagy", "pink1 prkn", "prkn mediated", "mediated mitophagy", "pink1 prkn mediated", "prkn mediated mitophagy", "pink1 prkn mediated mitophagy", "glycan", "trimming", "er", "calnexin/calreticulin", "cycle", "n glycan", "glycan trimming", "trimming in", "in the", "the er", "er and", "and calnexin/calreticulin", "calnexin/calreticulin cycle", "n glycan trimming", "glycan trimming in", "trimming in the", "in the er", "the er and", "er and calnexin/calreticulin", "and calnexin/calreticulin cycle", "n glycan trimming in", "glycan trimming in the", "trimming in the er", "in the er and", "the er and calnexin/calreticulin", "er and calnexin/calreticulin cycle", "n glycan trimming in the", "glycan trimming in the er", "trimming in the er and", "in the er and calnexin/calreticulin", "the er and calnexin/calreticulin cycle", "tnfr1", "of tnfr1", "tnfr1 signaling", "regulation of tnfr1", "of tnfr1 signaling", "regulation of tnfr1 signaling", "tnfr1 induced", "induced nf", "b signaling", "tnfr1 induced nf", "induced nf kappa", "kappa b signaling", "b signaling pathway", "tnfr1 induced nf kappa", "induced nf kappa b", "nf kappa b signaling", "kappa b signaling pathway", "tnfr1 induced nf kappa b", "induced nf kappa b signaling", "nf kappa b signaling pathway", "hedgehog", "ligand", "biogenesis", "hedgehog ligand", "ligand biogenesis", "hedgehog ligand biogenesis", "gli1", "proteasome", "of gli1", "gli1 by", "the proteasome", "degradation of gli1", "of gli1 by", "gli1 by the", "by the proteasome", "degradation of gli1 by", "of gli1 by the", "gli1 by the proteasome", "degradation of gli1 by the", "of gli1 by the proteasome", "gli3", "processed", "gli3r", "gli3 is", "is processed", "processed to", "to gli3r", "gli3r by", "gli3 is processed", "is processed to", "processed to gli3r", "to gli3r by", "gli3r by the", "gli3 is processed to", "is processed to gli3r", "processed to gli3r by", "to gli3r by the", "gli3r by the proteasome", "gli3 is processed to gli3r", "is processed to gli3r by", "processed to gli3r by the", "to gli3r by the proteasome", "'on'", "state", "hedgehog 'on'", "'on' state", "hedgehog 'on' state", "negative", "fgfr1", "negative regulation", "of fgfr1", "fgfr1 signaling", "negative regulation of", "regulation of fgfr1", "of fgfr1 signaling", "negative regulation of fgfr1", "regulation of fgfr1 signaling", "negative regulation of fgfr1 signaling", "fgfr2", "of fgfr2", "fgfr2 signaling", "regulation of fgfr2", "of fgfr2 signaling", "negative regulation of fgfr2", "regulation of fgfr2 signaling", "negative regulation of fgfr2 signaling", "fgfr3", "of fgfr3", "fgfr3 signaling", "regulation of fgfr3", "of fgfr3 signaling", "negative regulation of fgfr3", "regulation of fgfr3 signaling", "negative regulation of fgfr3 signaling", "fgfr4", "of fgfr4", "fgfr4 signaling", "regulation of fgfr4", "of fgfr4 signaling", "negative regulation of fgfr4", "regulation of fgfr4 signaling", "negative regulation of fgfr4 signaling", "polk", "by polk", "synthesis by polk", "translesion synthesis by polk", "poli", "by poli", "synthesis by poli", "translesion synthesis by poli", "termination", "termination of", "of translesion", "translesion dna", "dna synthesis", "termination of translesion", "of translesion dna", "translesion dna synthesis", "termination of translesion dna", "of translesion dna synthesis", "termination of translesion dna synthesis", "ras", "gaps", "of ras", "ras by", "by gaps", "regulation of ras", "of ras by", "ras by gaps", "regulation of ras by", "of ras by gaps", "regulation of ras by gaps", "tnfr2", "non", "canonical", "tnfr2 non", "non canonical", "canonical nf", "kb pathway", "tnfr2 non canonical", "non canonical nf", "canonical nf kb", "nf kb pathway", "tnfr2 non canonical nf", "non canonical nf kb", "canonical nf kb pathway", "tnfr2 non canonical nf kb", "non canonical nf kb pathway", "of mapk", "mapk pathway", "regulation of mapk", "of mapk pathway", "negative regulation of mapk", "regulation of mapk pathway", "negative regulation of mapk pathway", "necroptotic", "cell", "death", "of necroptotic", "necroptotic cell", "cell death", "regulation of necroptotic", "of necroptotic cell", "necroptotic cell death", "regulation of necroptotic cell", "of necroptotic cell death", "regulation of necroptotic cell death", "map3k8", "tpl2", "mapk1/3", "dependent mapk1/3", "mapk1/3 activation", "map3k8 tpl2", "tpl2 dependent", "dependent mapk1/3 activation", "tpl2 dependent mapk1/3", "map3k8 tpl2 dependent", "tpl2 dependent mapk1/3 activation", "hdr", "through", "homologous", "recombination", "hrr", "hdr through", "through homologous", "homologous recombination", "hdr through homologous", "through homologous recombination", "recombination hrr", "hdr through homologous recombination", "homologous recombination hrr", "through homologous recombination hrr", "mapk6/mapk4", "mapk6/mapk4 signaling", "uch", "proteinases", "uch proteinases", "josephin", "domain", "dubs", "josephin domain", "domain dubs", "josephin domain dubs", "ub", "specific", "processing", "proteases", "ub specific", "specific processing", "processing proteases", "ub specific processing", "specific processing proteases", "ub specific processing proteases", "ovarian", "tumor", "ovarian tumor", "tumor domain", "domain proteases", "ovarian tumor domain", "tumor domain proteases", "ovarian tumor domain proteases", "metalloprotease", "metalloprotease dubs", "resolution", "loop", "structures", "resolution of", "of d", "d loop", "loop structures", "resolution of d", "of d loop", "d loop structures", "resolution of d loop", "of d loop structures", "resolution of d loop structures", "recruitment", "atm", "repair", "double", "strand", "breaks", "recruitment and", "and atm", "atm mediated", "mediated phosphorylation", "phosphorylation of", "of repair", "repair and", "and signaling", "signaling proteins", "proteins at", "at dna", "dna double", "double strand", "strand breaks", "recruitment and atm", "and atm mediated", "atm mediated phosphorylation", "mediated phosphorylation of", "phosphorylation of repair", "of repair and", "repair and signaling", "and signaling proteins", "signaling proteins at", "proteins at dna", "at dna double", "dna double strand", "double strand breaks", "recruitment and atm mediated", "and atm mediated phosphorylation", "atm mediated phosphorylation of", "mediated phosphorylation of repair", "phosphorylation of repair and", "of repair and signaling", "repair and signaling proteins", "and signaling proteins at", "signaling proteins at dna", "proteins at dna double", "at dna double strand", "dna double strand breaks", "recruitment and atm mediated phosphorylation", "and atm mediated phosphorylation of", "atm mediated phosphorylation of repair", "mediated phosphorylation of repair and", "phosphorylation of repair and signaling", "of repair and signaling proteins", "repair and signaling proteins at", "and signaling proteins at dna", "signaling proteins at dna double", "proteins at dna double strand", "at dna double strand breaks", "gg", "ner", "damage recognition", "recognition in", "in gg", "gg ner", "dna damage recognition", "damage recognition in", "recognition in gg", "in gg ner", "dna damage recognition in", "damage recognition in gg", "recognition in gg ner", "dna damage recognition in gg", "damage recognition in gg ner", "formation", "incision", "formation of", "of incision", "incision complex", "complex in", "formation of incision", "of incision complex", "incision complex in", "complex in gg", "formation of incision complex", "of incision complex in", "incision complex in gg", "complex in gg ner", "formation of incision complex in", "of incision complex in gg", "incision complex in gg ner", "gap", "filling", "ligation", "gap filling", "filling dna", "dna repair", "repair synthesis", "synthesis and", "and ligation", "ligation in", "gap filling dna", "filling dna repair", "dna repair synthesis", "repair synthesis and", "synthesis and ligation", "and ligation in", "ligation in gg", "gap filling dna repair", "filling dna repair synthesis", "dna repair synthesis and", "repair synthesis and ligation", "synthesis and ligation in", "and ligation in gg", "ligation in gg ner", "gap filling dna repair synthesis", "filling dna repair synthesis and", "dna repair synthesis and ligation", "repair synthesis and ligation in", "synthesis and ligation in gg", "and ligation in gg ner", "dual", "dual incision", "incision in", "dual incision in", "incision in gg", "dual incision in gg", "incision in gg ner", "dual incision in gg ner", "tc", "pre", "of tc", "tc ner", "ner pre", "pre incision", "formation of tc", "of tc ner", "tc ner pre", "ner pre incision", "pre incision complex", "formation of tc ner", "of tc ner pre", "tc ner pre incision", "ner pre incision complex", "formation of tc ner pre", "of tc ner pre incision", "tc ner pre incision complex", "in tc", "incision in tc", "in tc ner", "dual incision in tc", "incision in tc ner", "dual incision in tc ner", "ligation in tc", "and ligation in tc", "ligation in tc ner", "synthesis and ligation in tc", "and ligation in tc ner", "fanconi", "anemia", "fanconi anemia", "anemia pathway", "fanconi anemia pathway", "major", "rrna", "nucleolus", "cytosol", "major pathway", "pathway of", "of rrna", "rrna processing", "processing in", "the nucleolus", "nucleolus and", "and cytosol", "major pathway of", "pathway of rrna", "of rrna processing", "rrna processing in", "processing in the", "in the nucleolus", "the nucleolus and", "nucleolus and cytosol", "major pathway of rrna", "pathway of rrna processing", "of rrna processing in", "rrna processing in the", "processing in the nucleolus", "in the nucleolus and", "the nucleolus and cytosol", "major pathway of rrna processing", "pathway of rrna processing in", "of rrna processing in the", "rrna processing in the nucleolus", "processing in the nucleolus and", "in the nucleolus and cytosol", "tp53", "of tp53", "tp53 activity", "activity through", "through phosphorylation", "regulation of tp53", "of tp53 activity", "tp53 activity through", "activity through phosphorylation", "regulation of tp53 activity", "of tp53 activity through", "tp53 activity through phosphorylation", "regulation of tp53 activity through", "of tp53 activity through phosphorylation", "tp53 degradation", "of tp53 degradation", "regulation of tp53 degradation", "met", "of met", "met activity", "regulation of met", "of met activity", "negative regulation of met", "regulation of met activity", "negative regulation of met activity", "assembly", "replicative", "assembly of", "the pre", "pre replicative", "replicative complex", "assembly of the", "of the pre", "the pre replicative", "pre replicative complex", "assembly of the pre", "of the pre replicative", "the pre replicative complex", "assembly of the pre replicative", "of the pre replicative complex", "orc1", "removal", "from", "chromatin", "orc1 removal", "removal from", "from chromatin", "orc1 removal from", "removal from chromatin", "orc1 removal from chromatin", "cdk", "cdc6", "cdk mediated", "and removal", "removal of", "of cdc6", "cdk mediated phosphorylation", "mediated phosphorylation and", "phosphorylation and removal", "and removal of", "removal of cdc6", "cdk mediated phosphorylation and", "mediated phosphorylation and removal", "phosphorylation and removal of", "and removal of cdc6", "cdk mediated phosphorylation and removal", "mediated phosphorylation and removal of", "phosphorylation and removal of cdc6", "events", "cyclin d", "d associated", "associated events", "events in", "in g1", "cyclin d associated", "d associated events", "associated events in", "events in g1", "cyclin d associated events", "d associated events in", "associated events in g1", "cyclin d associated events in", "d associated events in g1", "checkpoints", "g2/m checkpoints", "stabilization", "p53", "stabilization of", "of p53", "stabilization of p53", "phosphorylated", "cdc25a", "ubiquitin mediated", "of phosphorylated", "phosphorylated cdc25a", "ubiquitin mediated degradation", "degradation of phosphorylated", "of phosphorylated cdc25a", "ubiquitin mediated degradation of", "mediated degradation of phosphorylated", "degradation of phosphorylated cdc25a", "ubiquitin mediated degradation of phosphorylated", "mediated degradation of phosphorylated cdc25a", "pool", "free", "40s", "subunits", "of a", "a pool", "pool of", "of free", "free 40s", "40s subunits", "formation of a", "of a pool", "a pool of", "pool of free", "of free 40s", "free 40s subunits", "formation of a pool", "of a pool of", "a pool of free", "pool of free 40s", "of free 40s subunits", "formation of a pool of", "of a pool of free", "a pool of free 40s", "pool of free 40s subunits", "ubiquitin dependent", "dependent degradation", "ubiquitin dependent degradation", "dependent degradation of", "of cyclin d", "ubiquitin dependent degradation of", "dependent degradation of cyclin", "degradation of cyclin d", "ubiquitin dependent degradation of 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